Joseph Mizgerd | Profiles RNS

Joseph P. Mizgerd, ScD Hear my name

Professor

Boston University Chobanian & Avedisian School of Medicine

Medicine

Pulmonary, Allergy, Sleep & Critical Care Medicine

ScD, Harvard School of Public Health
BA, Amherst College

Pronouns: he/him/his

Websites

	Pneumonia Biology
	Pulmonary Center
	Pulmonary, Allergy, Sleep & Critical Care Medicine Faculty
	2020 University Lecture

ORCID : 0000-0002-4042-3169

Our work focuses on immunology in the lung and its influence on acute lower respiratory tract infections. Our research is illuminating the regulation and function of innate and adaptive immune cells and signals in the lung, and how variations in these parameters determine pneumonia susceptibility and outcome. Lung defense consists of immune resistance (the ability to eliminate microbes) and tissue resilience (the ability to prevent or withstand injurious stimuli from infection and inflammation). Both activities are accomplished by the coordinated activities of diverse cell types within the lung, involving some that are constitutively present (including diverse types of epithelial cells, macrophages, lymphocytes, and more) as well as others newly recruited to the infected tissue (including neutrophils plus additional myeloid or lymphoid cells). Effective and productive communication amongst these cells can efficiently destroy microbes without damaging the lung, maintaining respiratory health. Dysregulation of these pathways instead promotes infection (e.g., pneumonia), injury (e.g., the acute respiratory distress syndrome), and other pulmonary diseases. Elucidating factors that differentiate lung infection resistance and susceptibility will enable new approaches to preventing and treating pneumonia.

Director
Boston University Chobanian & Avedisian School of Medicine
Pulmonary Center

Professor
Boston University Chobanian & Avedisian School of Medicine
Biochemistry & Cell Biology

Professor
Boston University Chobanian & Avedisian School of Medicine
Virology, Immunology & Microbiology

Member
Boston University
Evans Center for Interdisciplinary Biomedical Research

Member
Boston University
Genome Science Institute

Graduate Medical Sciences Educator and Mentor (Primary Mentor of Graduate Students)
Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences

BU Research
NIH RePORTER Research

Fibrin in the Infected Lung
02/15/2024 - 01/31/2028 (PI)
NIH/National Heart, Lung, and Blood Institute
5R01HL171499-02

Lung interstitial macrophage remodeling during and after recovery from pneumococcal respiratory infection
09/01/2025 - 08/31/2027 (Key Person / Mentor)
NIH/National Heart, Lung, and Blood Institute
1F31HL178234-01A1

LOX-1 as a protective countermeasure in response to lung infection
06/15/2023 - 05/31/2027 (Subcontract PI)
University of Massachusetts, Medical School NIH NHLBI
5R01HL165718-02

Pulmonary pathophysiology sub-phenotypes of pneumonia
02/01/2022 - 01/31/2027 (PI)
NIH/National Institute of Allergy & Infectious Diseases
5R01AI162850-04

Biology of the Lung: A Multidisciplinary Program
07/01/2021 - 06/30/2026 (Multi-PI)
PI: Joseph P. Mizgerd, ScD
NIH/National Heart, Lung, and Blood Institute
5T32HL007035-48

Sub-phenotyping pneumonia by lung pathobiology
09/01/2023 - 06/30/2025 (Key Person / Mentor)
PI: Bradley E. Hiller, Ph.D.
NIH/National Heart, Lung, and Blood Institute
5F32HL170650-02

Lung-resident antibacterial heterotypic immunity
07/01/2019 - 06/30/2025 (PI)
NIH/National Institute of Allergy & Infectious Diseases
5R01AI115053-09

Protective lung memory B cell functions and dynamics during respiratory infection
06/01/2021 - 05/31/2025 (Key Person / Mentor)
PI: Neelou Etesami
NIH/National Heart, Lung, and Blood Institute
5F30HL158109-04

Pneumonia Biology
01/11/2017 - 12/31/2024 (PI)
NIH/National Heart, Lung, and Blood Institute
5R35HL135756-07

PASC Pathobiology: long-term remodeling after acute infection
03/01/2022 - 02/29/2024 (Subcontract PI)
President & Fellows of Harvard College on behalf of Harvard Medical School China Evergrande Gr

Showing 10 of 27 results. Show All Results

Title

Yr	Title	Project-Sub Proj
2025	The anatomy of T-cell mediated neutrophil recruitment during lung infection	1R21AI191650-01
2025	Fibrin in the Infected Lung	5R01HL171499-02
2025	Pulmonary pathophysiology sub-phenotypes of pneumonia	5R01AI162850-04
2025	Biology of the Lung: A Multidisciplinary Program	5T32HL007035-50
2024	Fibrin in the Infected Lung	1R01HL171499-01
2024	Pulmonary pathophysiology sub-phenotypes of pneumonia	5R01AI162850-03
2024	Biology of the Lung: A Multidisciplinary Program	5T32HL007035-49
2023	Pulmonary pathophysiology sub-phenotypes of pneumonia	5R01AI162850-02
2023	Pneumonia Biology	5R35HL135756-07
2023	Lung-resident antibacterial heterotypic immunity	5R01AI115053-09

Showing 10 of 69 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Website Copy PMIDs To Clipboard

Samarasinghe AE, Randell SH, Kulkarni HS, Weiser JN, Quinton LJ, Dickson RP, Mizgerd JP, Orihuela CJ, Parker D, Robinson KM, Prince AS, Evans SE, Kolls JK, Lee JS, Jeyaseelan S, Torres A, Miller LA, Hamilton DJ, Gómez MI, Moore BB, Walker RL, Barkal LJ, Hook JL, Lau GW, Sharma J, Witzenrath M, Dela Cruz CS. Best Practices in the Development and Use of Experimental Models of Bacterial Pneumonia: An Official American Thoracic Society Workshop Report. Am J Respir Cell Mol Biol. 2025 Aug; 73(2):178-199.View Related Profiles.

Mizgerd, Joseph
Quinton, Lee

PMID: 40748059; PMCID: PMC12334885; DOI: 10.1165/rcmb.2025-0322ST;

Caobi A, Su CM, Beusch CM, Kenney D, Darling TL, Feng S, Semaan M, Wacquiez A, Sanders NL, Tully ES, Chen DY, Evdokimova M, Ding Z, Jones D, Alysandratos KD, Mizgerd JP, Kirchdoerfer RN, Kotton DN, Douam F, Crossland NA, Boon ACM, Gordon DE, Baker SC, Saeed M. SARS-CoV-2 nsp15 enhances viral virulence by subverting host antiviral defenses. Proc Natl Acad Sci U S A. 2025 Jun 17; 122(24):e2426528122.View Related Profiles.

Wacquiez, Alan Cyril Jacques
Caobi, Allen
Kotton, Darrell
Kenney, Devin James
Douam, Florian
Mizgerd, Joseph
Alysandratos, Kostas
Saeed, Mohsan
Crossland, Nicholas

PMID: 40504150; PMCID: PMC12184426; DOI: 10.1073/pnas.2426528122;

Fredberg JJ, Mizgerd JP. Combining innovative methodologies with deep personal connections to further physiology research: lessons from Joseph D. Brain, ScD. Am J Physiol Lung Cell Mol Physiol. 2025 Aug 01; 329(2):L197-L199. PMID: 40454782

Shastry A, Hiller BE, Sanders NL, Tseng AE, Kothari J, O'Connell AK, Gertje HP, Ha CT, Murzin E, Traber KE, Lederer JA, Jones MR, Douam F, Beach TG, Remick DG, Crossland NA, Monti S, Campbell JD, Mizgerd JP. Sub-phenotypes of pneumonia defined by pulmonary histopathological features. bioRxiv. 2025 May 20.View Related Profiles.

Hiller, Bradley
Douam, Florian
Mizgerd, Joseph
Traber, Katrina
Crossland, Nicholas
Monti, Stefano

PMID: 40475544; PMCID: PMC12139937; DOI: 10.1101/2025.05.18.654716;

Vasquez JH, Yuan J, Leow CJ, Crossey E, Shao F, Carty S, Dominguez VA, Lo M, Mizgerd JP, Fetterman JL, Lau NC, Fine A, Jones MR. Somatic Miwi2 modulates mitochondrial function in airway multiciliated cells and exacerbates influenza pathogenesis. iScience. 2025 Apr 18; 28(4):112291.View Related Profiles.

Fine, Alan
Crossey, Erin
Fetterman, Jessica
Mizgerd, Joseph
Jones, Matthew
Lo, Ming
Lau, Nelson

PMID: 40241756; PMCID: PMC12002665; DOI: 10.1016/j.isci.2025.112291;

Traber KE, Mizgerd JP. The Integrated Pulmonary Immune Response to Pneumonia. Annu Rev Immunol. 2025 Apr; 43(1):545-569.View Related Profiles.

Mizgerd, Joseph
Traber, Katrina

PMID: 40036700; DOI: 10.1146/annurev-immunol-082323-031642;

Soucy AM, Brune JE, Jayaraman A, Shenoy AT, Korkmaz FT, Etesami NS, Hiller BE, Martin IM, Goltry WN, Ha CT, Crossland NA, Campbell JD, Beach TG, Traber KE, Jones MR, Quinton LJ, Bosmann M, Frevert CW, Mizgerd JP. Transcriptomic responses of lung mesenchymal cells during pneumonia. JCI Insight. 2025 Feb 25; 10(7).View Related Profiles.

Soucy, Alicia
Jayaraman, Archana
Hiller, Bradley
Korkmaz, Filiz
Mizgerd, Joseph
Campbell, Joshua
Traber, Katrina
Quinton, Lee
Bosmann, Markus
Jones, Matthew
Etesami, Neelou
Crossland, Nicholas

PMID: 39998887; PMCID: PMC11981624; DOI: 10.1172/jci.insight.177084;

Ravi VR, Korkmaz FT, De Ana CL, Lu L, Shao FZ, Odom CV, Barker KA, Ramanujan A, Niszczak EN, Goltry WN, Martin IMC, Ha CT, Quinton LJ, Jones MR, Fine A, Welch JD, Chen F, Belkina AC, Mizgerd JP, Shenoy AT. Lung CD4+ resident memory T cells use airway secretory cells to stimulate and regulate onset of allergic airway neutrophilic disease. Cell Rep. 2025 Mar 25; 44(3):115294.View Related Profiles.

Fine, Alan
Belkina, Anna
Korkmaz, Filiz
Mizgerd, Joseph
Quinton, Lee
Jones, Matthew

PMID: 39965565; PMCID: PMC12011213; DOI: 10.1016/j.celrep.2025.115294;

Harlow OS, Ravi VR, Ke F, Sanders NL, Armstrong E, Mizgerd JP, Shenoy AT. The mysterious case of missing lymphocytes: a cautionary tale of interinstitutional variability in outcomes of lung dissociation protocols. Am J Physiol Lung Cell Mol Physiol. 2025 Feb 01; 328(2):L260-L266. PMID: 39786964; PMCID: PMC12178127; DOI: 10.1152/ajplung.00323.2024;

Yin J, Hayes KM, Ong MS, Mizgerd JP, Cunningham-Rundles C, Dominguez I, Barmettler S, Farmer JR, Maglione PJ. Common Variable Immunodeficiency Clinical Manifestations Are Shaped by Presence and Type of Heterozygous NFKB1 Variants. J Allergy Clin Immunol Pract. 2025 Mar; 13(3):639-646.View Related Profiles.

Mizgerd, Joseph
Dominguez, Maria
Maglione, Paul

PMID: 39672378; PMCID: PMC11885011; DOI: 10.1016/j.jaip.2024.12.002;

Showing 10 of 157 results. Show More

Deshmukh H, Whitsett J, Zacharias W, Way SS, Martinez FD, Mizgerd J, Pryhuber G, Ambalavanan N, Bacharier L, Natarajan A, Tamburro R, Lin S, Randolph A, Nino G, Mejias A, Ramilo O. Impact of Viral Lower Respiratory Tract Infection (LRTI) in Early Childhood (0-2 Years) on Lung Growth and Development and Lifelong Trajectories of Pulmonary Health: A National Institutes of Health (NIH) Workshop Summary. Pediatr Pulmonol. 2025 Jan; 60(1):e27357. PMID: 39565217; PMCID: PMC11740654; DOI: 10.1002/ppul.27357;

Hiller BE, Mizgerd JP. IFN-? and YAP lead epithelial cells astray after severe respiratory infection. J Clin Invest. 2024 Oct 01; 134(19).View Related Profiles.

Hiller, Bradley
Mizgerd, Joseph

PMID: 39352386; PMCID: PMC11444161; DOI: 10.1172/JCI185072;

Auld SC, Sheshadri A, Alexander-Brett J, Aschner Y, Barczak AK, Basil MC, Cohen KA, Dela Cruz C, McGroder C, Restrepo MI, Ridge KM, Schnapp LM, Traber K, Wunderink RG, Zhang D, Ziady A, Attia EF, Carter J, Chalmers JD, Crothers K, Feldman C, Jones BE, Kaminski N, Keane J, Lewinsohn D, Metersky M, Mizgerd JP, Morris A, Ramirez J, Samarasinghe AE, Staitieh BS, Stek C, Sun J, Evans SE. Postinfectious Pulmonary Complications: Establishing Research Priorities to Advance the Field: An Official American Thoracic Society Workshop Report. Ann Am Thorac Soc. 2024 Sep; 21(9):1219-1237.View Related Profiles.

Mizgerd, Joseph
Traber, Katrina

PMID: 39051991; PMCID: PMC12392397; DOI: 10.1513/AnnalsATS.202406-651ST;

Lee MM, Zuo Y, Steiling K, Mizgerd JP, Kalesan B, Walkey AJ. Clinical risk factors and blood protein biomarkers of 10-year pneumonia risk. PLoS One. 2024; 19(7):e0296139.View Related Profiles.

Walkey, Allan
Kalesan, Bindu
Mizgerd, Joseph
Steiling, Katrina

PMID: 38968193; PMCID: PMC11226120; DOI: 10.1371/journal.pone.0296139;

Ysasi AB, Engler AE, Bawa PS, Wang F, Conrad RD, Yeung AK, Rock JR, Beane-Ebel J, Mazzilli SA, Franklin RA, Mizgerd JP, Murphy GJ. A specialized population of monocyte-derived tracheal macrophages promote airway epithelial regeneration through a CCR2-dependent mechanism. iScience. 2024 Jul 19; 27(7):110169.View Related Profiles.

Engler, Anna
Murphy, George
Beane-Ebel, Jennifer
Mizgerd, Joseph
Mazzilli, Sarah

PMID: 38993668; PMCID: PMC11238131; DOI: 10.1016/j.isci.2024.110169;

Etesami NS, Barker KA, Shenoy AT, De Ana CL, Arafa EI, Grifno GN, Matschulat AM, Vannini ME, Pihl RMF, Breen MP, Soucy AM, Goltry WN, Ha CT, Betsuyaku H, Browning JL, Varelas X, Traber KE, Jones MR, Quinton LJ, Maglione PJ, Nia HT, Belkina AC, Mizgerd JP. B cells in the pneumococcus-infected lung are heterogeneous and require CD4+ T cell help including CD40L to become resident memory B cells. Front Immunol. 2024; 15:1382638.View Related Profiles.

Soucy, Alicia
Belkina, Anna
Nia, Hadi
Browning, Jeffrey
Mizgerd, Joseph
Traber, Katrina
Quinton, Lee
Jones, Matthew
Breen, Michael
Etesami, Neelou
Maglione, Paul
Pihl, Riley
Varelas, Xaralabos

PMID: 38715601; PMCID: PMC11074383; DOI: 10.3389/fimmu.2024.1382638;

Lee MM, Zuo Y, Steiling K, Mizgerd JP, Kalesan B, Walkey AJ. Clinical risk factors and blood protein biomarkers of 10-year pneumonia risk. medRxiv. 2023 Dec 09.View Related Profiles.

Walkey, Allan
Kalesan, Bindu
Mizgerd, Joseph
Steiling, Katrina

PMID: 38105941; PMCID: PMC10723561; DOI: 10.1101/2023.12.07.23299678;

Lyon De Ana C, Shenoy AT, Barker KA, Arafa EI, Etesami NS, Korkmaz FT, Soucy AM, Breen MP, Martin IMC, Tilton BR, Devarajan P, Crossland NA, Pihl RMF, Goltry WN, Belkina AC, Jones MR, Quinton LJ, Mizgerd JP. GL7 ligand expression defines a novel subset of CD4+ TRM cells in lungs recovered from pneumococcus. Mucosal Immunol. 2023 Oct; 16(5):699-710.View Related Profiles.

Soucy, Alicia
Belkina, Anna
Korkmaz, Filiz
Mizgerd, Joseph
Quinton, Lee
Jones, Matthew
Breen, Michael
Etesami, Neelou
Crossland, Nicholas
Pihl, Riley

PMID: 37604254; PMCID: PMC10591822; DOI: 10.1016/j.mucimm.2023.07.004;

Banerji R, Grifno GN, Shi L, Smolen D, LeBourdais R, Muhvich J, Eberman C, Hiller BE, Lee J, Regan K, Zheng S, Zhang S, Jiang J, Raslan AA, Breda JC, Pihl R, Traber K, Mazzilli S, Ligresti G, Mizgerd JP, Suki B, Nia HT. Crystal ribcage: a platform for probing real-time lung function at cellular resolution. Nat Methods. 2023 Nov; 20(11):1790-1801.View Related Profiles.

Raslan, Ahmed
Hiller, Bradley
Ligresti, Giovanni
Nia, Hadi
Mizgerd, Joseph
Traber, Katrina
Mazzilli, Sarah

PMID: 37710017; PMCID: PMC10860663; DOI: 10.1038/s41592-023-02004-9;

Aihara F, Wang Y, Belkina AC, Fearns R, Mizgerd JP, Feng F, Kepler TB. Diversity of B Cell Populations and Ig Repertoire in Human Lungs. J Immunol. 2023 Aug 01; 211(3):486-496.View Related Profiles.

Belkina, Anna
Aihara, Fumiaki
Mizgerd, Joseph
Fearns, Rachel
Kepler, Thomas

PMID: 37314411; PMCID: PMC10352589; DOI: 10.4049/jimmunol.2200340;

Center DM, Mizgerd JP. In Memoriam: Jerome S. Brody, M.D., A Red Journal Founder. Am J Respir Cell Mol Biol. 2023 May; 68(5):465-466.View Related Profiles.

Center, David
Mizgerd, Joseph

PMID: 36780672; PMCID: PMC10174165; DOI: 10.1165/rcmb.2023-0044ED;

Korkmaz FT, Shenoy AT, Symer EM, Baird LA, Odom CV, Arafa EI, Dimbo EL, Na E, Molina-Arocho W, Brudner M, Standiford TJ, Mehta JL, Sawamura T, Jones MR, Mizgerd JP, Traber KE, Quinton LJ. Lectin-like oxidized low-density lipoprotein receptor 1 attenuates pneumonia-induced lung injury. JCI Insight. 2022 Dec 08; 7(23).View Related Profiles.

Shenoy, Anukul
Korkmaz, Filiz
Mizgerd, Joseph
Traber, Katrina
Quinton, Lee
Jones, Matthew

PMID: 36264633; PMCID: PMC9746901; DOI: 10.1172/jci.insight.149955;

Serrano GE, Walker JE, Tremblay C, Piras IS, Huentelman MJ, Belden CM, Goldfarb D, Shprecher D, Atri A, Adler CH, Shill HA, Driver-Dunckley E, Mehta SH, Caselli R, Woodruff BK, Haarer CF, Ruhlen T, Torres M, Nguyen S, Schmitt D, Rapscak SZ, Bime C, Peters JL, Alevritis E, Arce RA, Glass MJ, Vargas D, Sue LI, Intorcia AJ, Nelson CM, Oliver J, Russell A, Suszczewicz KE, Borja CI, Cline MP, Hemmingsen SJ, Qiji S, Hobgood HM, Mizgerd JP, Sahoo MK, Zhang H, Solis D, Montine TJ, Berry GJ, Reiman EM, Röltgen K, Boyd SD, Pinsky BA, Zehnder JL, Talbot P, Desforges M, DeTure M, Dickson DW, Beach TG. SARS-CoV-2 Brain Regional Detection, Histopathology, Gene Expression, and Immunomodulatory Changes in Decedents with COVID-19. J Neuropathol Exp Neurol. 2022 Aug 16; 81(9):666-695. PMID: 35818336; PMCID: PMC9278252; DOI: 10.1093/jnen/nlac056;

Arafa EI, Shenoy AT, Barker KA, Etesami NS, Martin IM, Lyon De Ana C, Na E, Odom CV, Goltry WN, Korkmaz FT, Wooten AK, Belkina AC, Guillon A, Forsberg EC, Jones MR, Quinton LJ, Mizgerd JP. Recruitment and training of alveolar macrophages after pneumococcal pneumonia. JCI Insight. 2022 Mar 08; 7(5).View Related Profiles.

Wooten, Alicia
Belkina, Anna
Shenoy, Anukul
Korkmaz, Filiz
Mizgerd, Joseph
Quinton, Lee
Jones, Matthew
Etesami, Neelou

PMID: 35133985; PMCID: PMC8983128; DOI: 10.1172/jci.insight.150239;

Na E, Allen E, Baird LA, Odom CV, Korkmaz FT, Shenoy AT, Matschulat AM, Jones MR, Kotton DN, Mizgerd JP, Varelas X, Traber KE, Quinton LJ. Epithelial LIF signaling limits apoptosis and lung injury during bacterial pneumonia. Am J Physiol Lung Cell Mol Physiol. 2022 Apr 01; 322(4):L550-L563.View Related Profiles.

Shenoy, Anukul
Kotton, Darrell
Korkmaz, Filiz
Mizgerd, Joseph
Traber, Katrina
Quinton, Lee
Jones, Matthew
Varelas, Xaralabos

PMID: 35137631; PMCID: PMC8957336; DOI: 10.1152/ajplung.00325.2021;

Sanders NL, Martin IMC, Sharma A, Jones MR, Quinton LJ, Bosmann M, Mizgerd JP. Neutrophil Extracellular Traps as an Exacerbating Factor in Bacterial Pneumonia. Infect Immun. 2022 03 17; 90(3):e0049121.View Related Profiles.

Mizgerd, Joseph
Quinton, Lee
Bosmann, Markus
Jones, Matthew

PMID: 35130455; PMCID: PMC8929384; DOI: 10.1128/iai.00491-21;

Kulkarni HS, Lee JS, Bastarache JA, Kuebler WM, Downey GP, Albaiceta GM, Altemeier WA, Artigas A, Bates JHT, Calfee CS, Dela Cruz CS, Dickson RP, Englert JA, Everitt JI, Fessler MB, Gelman AE, Gowdy KM, Groshong SD, Herold S, Homer RJ, Horowitz JC, Hsia CCW, Kurahashi K, Laubach VE, Looney MR, Lucas R, Mangalmurti NS, Manicone AM, Martin TR, Matalon S, Matthay MA, McAuley DF, McGrath-Morrow SA, Mizgerd JP, Montgomery SA, Moore BB, Noël A, Perlman CE, Reilly JP, Schmidt EP, Skerrett SJ, Suber TL, Summers C, Suratt BT, Takata M, Tuder R, Uhlig S, Witzenrath M, Zemans RL, Matute-Bello G. Update on the Features and Measurements of Experimental Acute Lung Injury in Animals: An Official American Thoracic Society Workshop Report. Am J Respir Cell Mol Biol. 2022 02; 66(2):e1-e14. PMID: 35103557; PMCID: PMC8845128; DOI: 10.1165/rcmb.2021-0531ST;

Murray MP, Crosby CM, Marcovecchio P, Hartmann N, Chandra S, Zhao M, Khurana A, Zahner SP, Clausen BE, Coleman FT, Mizgerd JP, Mikulski Z, Kronenberg M. Stimulation of a subset of natural killer T cells by CD103+ DC is required for GM-CSF and protection from pneumococcal infection. Cell Rep. 2022 01 11; 38(2):110209.View Related Profiles.

Coleman, Fadie
Mizgerd, Joseph

PMID: 35021099; PMCID: PMC8934033; DOI: 10.1016/j.celrep.2021.110209;

Shenoy AT, Lyon De Ana C, Barker KA, Arafa EI, Martin IMC, Mizgerd JP, Belkina AC. CPHEN-011: Comprehensive phenotyping of murine lung resident lymphocytes after recovery from pneumococcal pneumonia. Cytometry A. 2022 Nov; 101(11):892-902.View Related Profiles.

Belkina, Anna
Shenoy, Anukul
Mizgerd, Joseph

PMID: 34854229; PMCID: PMC9160214; DOI: 10.1002/cyto.a.24522;

Shenoy AT, Lyon De Ana C, Arafa EI, Salwig I, Barker KA, Korkmaz FT, Ramanujan A, Etesami NS, Soucy AM, Martin IMC, Tilton BR, Hinds A, Goltry WN, Kathuria H, Braun T, Jones MR, Quinton LJ, Belkina AC, Mizgerd JP. Antigen presentation by lung epithelial cells directs CD4+ TRM cell function and regulates barrier immunity. Nat Commun. 2021 10 05; 12(1):5834.View Related Profiles.

Soucy, Alicia
Belkina, Anna
Shenoy, Anukul
Korkmaz, Filiz
Kathuria, Hasmeena
Mizgerd, Joseph
Quinton, Lee
Jones, Matthew
Etesami, Neelou

PMID: 34611166; PMCID: PMC8492657; DOI: 10.1038/s41467-021-26045-w;

Odom CV, Kim Y, Burgess CL, Baird LA, Korkmaz FT, Na E, Shenoy AT, Arafa EI, Lam TT, Jones MR, Mizgerd JP, Traber KE, Quinton LJ. Liver-Dependent Lung Remodeling during Systemic Inflammation Shapes Responses to Secondary Infection. J Immunol. 2021 10 01; 207(7):1891-1902.View Related Profiles.

Shenoy, Anukul
Korkmaz, Filiz
Mizgerd, Joseph
Traber, Katrina
Quinton, Lee
Jones, Matthew

PMID: 34470857; PMCID: PMC8631467; DOI: 10.4049/jimmunol.2100254;

Keefe J, Yao C, Hwang SJ, Courchesne P, Lee GY, Dupuis J, Mizgerd JP, O'Connor G, Washko GR, Cho MH, Silverman EK, Levy D. An Integrative Genomic Strategy Identifies sRAGE as a Causal and Protective Biomarker of Lung Function. Chest. 2022 01; 161(1):76-84.View Related Profiles.

Levy, Daniel
O'Connor, George
Dupuis, Josee
Mizgerd, Joseph
Hwang, Shih-Jen

PMID: 34237330; PMCID: PMC8783029; DOI: 10.1016/j.chest.2021.06.053;

Dela Cruz CS, Evans SE, Restrepo MI, Dean N, Torres A, Amara-Elori I, Awasthi S, Caler E, Cao B, Chalmers JD, Chastre J, Cohen TS, Cohen AH, Crothers K, Di YP, Egan ME, Feldman C, Gautam S, Halstead ES, Herold S, Jones BE, Luna C, Niederman MS, Mendez R, Menendez R, Mizgerd JP, Nusrat R, Ramirez J, Shindo Y, Waterer G, Yeligar SM, Wunderink RG. Understanding the Host in the Management of Pneumonia. An Official American Thoracic Society Workshop Report. Ann Am Thorac Soc. 2021 07; 18(7):1087-1097. PMID: 34242148; PMCID: PMC8328365; DOI: 10.1513/AnnalsATS.202102-209ST;

Barker KA, Etesami NS, Shenoy AT, Arafa EI, Lyon de Ana C, Smith NM, Martin IM, Goltry WN, Barron AM, Browning JL, Kathuria H, Belkina AC, Guillon A, Zhong X, Crossland NA, Jones MR, Quinton LJ, Mizgerd JP. Lung-resident memory B cells protect against bacterial pneumonia. J Clin Invest. 2021 06 01; 131(11).View Related Profiles.

Belkina, Anna
Shenoy, Anukul
Kathuria, Hasmeena
Browning, Jeffrey
Mizgerd, Joseph
Quinton, Lee
Jones, Matthew
Etesami, Neelou
Crossland, Nicholas

PMID: 34060477; PMCID: PMC8159694; DOI: 10.1172/JCI141810;

Traber KE, Dimbo EL, Shenoy AT, Symer EM, Allen E, Mizgerd JP, Quinton LJ. Neutrophil-Derived Oncostatin M Triggers Diverse Signaling Pathways during Pneumonia. Infect Immun. 2021 03 17; 89(4).View Related Profiles.

Shenoy, Anukul
Mizgerd, Joseph
Traber, Katrina
Quinton, Lee

PMID: 33526570; PMCID: PMC8090961; DOI: 10.1128/IAI.00655-20;

Serrano GE, Walker JE, Arce R, Glass MJ, Vargas D, Sue LI, Intorcia AJ, Nelson CM, Oliver J, Papa J, Russell A, Suszczewicz KE, Borja CI, Belden C, Goldfarb D, Shprecher D, Atri A, Adler CH, Shill HA, Driver-Dunckley E, Mehta SH, Readhead B, Huentelman MJ, Peters JL, Alevritis E, Bimi C, Mizgerd JP, Reiman EM, Montine TJ, Desforges M, Zehnder JL, Sahoo MK, Zhang H, Solis D, Pinsky BA, Deture M, Dickson DW, Beach TG. Mapping of SARS-CoV-2 Brain Invasion and Histopathology in COVID-19 Disease. medRxiv. 2021 Feb 18. PMID: 33619496; PMCID: PMC7899461; DOI: 10.1101/2021.02.15.21251511;

Beach TG, Russell A, Sue LI, Intorcia AJ, Glass MJ, Walker JE, Arce R, Nelson CM, Hidalgo T, Chiarolanza G, Mariner M, Scroggins A, Pullen J, Souders L, Sivananthan K, Carter N, Saxon-LaBelle M, Hoffman B, Garcia A, Callan M, Fornwalt BE, Carew J, Filon J, Cutler B, Papa J, Curry JR, Oliver J, Shprecher D, Atri A, Belden C, Shill HA, Driver-Dunckley E, Mehta SH, Adler CH, Haarer CF, Ruhlen T, Torres M, Nguyen S, Schmitt D, Fietz M, Lue LF, Walker DG, Mizgerd JP, Serrano GE. Increased Risk of Autopsy-Proven Pneumonia with Sex, Season and Neurodegenerative Disease. medRxiv. 2021 Jan 08. PMID: 33442709; PMCID: PMC7805471; DOI: 10.1101/2021.01.07.21249410;

Shenoy AT, Mizgerd JP. Seedy CD8+ TRM cells in aging lungs drive susceptibility to pneumonia and sequelae. Cell Mol Immunol. 2021 04; 18(4):787-789.View Related Profiles.

Shenoy, Anukul
Mizgerd, Joseph

PMID: 33420355; PMCID: PMC7791330; DOI: 10.1038/s41423-020-00629-w;

Sagar M, Reifler K, Rossi M, Miller NS, Sinha P, White LF, Mizgerd JP. Recent endemic coronavirus infection is associated with less-severe COVID-19. J Clin Invest. 2021 01 04; 131(1).View Related Profiles.

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Reifler, Katherine
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Sinha, Pranay

PMID: 32997649; PMCID: PMC7773342; DOI: 10.1172/JCI143380;

Guillon A, Mizgerd JP, Grammatico-Guillon L. 2-year survival among elderly hospitalised for acute respiratory infection versus hip fracture: a useful comparison to raise awareness. Eur Respir Rev. 2020 Dec 31; 29(158). PMID: 33268438; PMCID: PMC9488726; DOI: 10.1183/16000617.0156-2020;

Semler MW, Bernard GR, Aaron SD, Angus DC, Biros MH, Brower RG, Calfee CS, Colantuoni EA, Ferguson ND, Gong MN, Hopkins RO, Hough CL, Iwashyna TJ, Levy BD, Martin TR, Matthay MA, Mizgerd JP, Moss M, Needham DM, Self WH, Seymour CW, Stapleton RD, Thompson BT, Wunderink RG, Aggarwal NR, Reineck LA. Identifying Clinical Research Priorities in Adult Pulmonary and Critical Care. NHLBI Working Group Report. Am J Respir Crit Care Med. 2020 Aug 15; 202(4):511-523. PMID: 32150460; PMCID: PMC7427373; DOI: 10.1164/rccm.201908-1595WS;

Wooten AK, Shenoy AT, Arafa EI, Akiyama H, Martin IMC, Jones MR, Quinton LJ, Gummuluru S, Bai G, Mizgerd JP. Unique Roles for Streptococcus pneumoniae Phosphodiesterase 2 in Cyclic di-AMP Catabolism and Macrophage Responses. Front Immunol. 2020; 11:554.View Related Profiles.

Wooten, Alicia
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PMID: 32300347; PMCID: PMC7145409; DOI: 10.3389/fimmu.2020.00554;

Guillon A, Arafa EI, Barker KA, Belkina AC, Martin I, Shenoy AT, Wooten AK, Lyon De Ana C, Dai A, Labadorf A, Hernandez Escalante J, Dooms H, Blasco H, Traber KE, Jones MR, Quinton LJ, Mizgerd JP. Pneumonia recovery reprograms the alveolar macrophage pool. JCI Insight. 2020 02 27; 5(4).View Related Profiles.

Labadorf, Adam
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Mizgerd, Joseph
Traber, Katrina
Quinton, Lee
Jones, Matthew

PMID: 31990682; PMCID: PMC7101156; DOI: 10.1172/jci.insight.133042;

Lin WC, Gowdy KM, Madenspacher JH, Zemans RL, Yamamoto K, Lyons-Cohen M, Nakano H, Janardhan K, Williams CJ, Cook DN, Mizgerd JP, Fessler MB. Epithelial membrane protein 2 governs transepithelial migration of neutrophils into the airspace. J Clin Invest. 2020 01 02; 130(1):157-170.View Related Profiles.

Mizgerd, Joseph
Yamamoto, Kazuko

PMID: 31550239; PMCID: PMC6934223; DOI: 10.1172/JCI127144;

Shenoy AT, Wasserman GA, Arafa EI, Wooten AK, Smith NMS, Martin IMC, Jones MR, Quinton LJ, Mizgerd JP. Lung CD4+ resident memory T cells remodel epithelial responses to accelerate neutrophil recruitment during pneumonia. Mucosal Immunol. 2020 03; 13(2):334-343.View Related Profiles.

Wooten, Alicia
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PMID: 31748706; PMCID: PMC7044037; DOI: 10.1038/s41385-019-0229-2;

Traber KE, Dimbo EL, Symer EM, Korkmaz FT, Jones MR, Mizgerd JP, Quinton LJ. Roles of interleukin-11 during acute bacterial pneumonia. PLoS One. 2019; 14(8):e0221029.View Related Profiles.

Korkmaz, Filiz
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PMID: 31415618; PMCID: PMC6695241; DOI: 10.1371/journal.pone.0221029;

Kim Y, Allen E, Baird LA, Symer EM, Korkmaz FT, Na E, Odom CV, Jones MR, Mizgerd JP, Traber KE, Quinton LJ. NF-?B RelA Is Required for Hepatoprotection during Pneumonia and Sepsis. Infect Immun. 2019 08; 87(8).View Related Profiles.

Korkmaz, Filiz
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PMID: 31160364; PMCID: PMC6652780; DOI: 10.1128/IAI.00132-19;

Mizgerd JP. Inflammation and Pneumonia: Why Are Some More Susceptible than Others? Clin Chest Med. 2018 12; 39(4):669-676. PMID: 30390740; PMCID: PMC6221464; DOI: 10.1016/j.ccm.2018.07.002;

Dela Cruz CS, Wunderink RG, Christiani DC, Cormier SA, Crothers K, Doerschuk CM, Evans SE, Goldstein DR, Khatri P, Kobzik L, Kolls JK, Levy BD, Metersky ML, Niederman MS, Nusrat R, Orihuela CJ, Peyrani P, Prince AS, Ramírez JA, Ridge KM, Sethi S, Suratt BT, Sznajder JI, Tsalik EL, Walkey AJ, Yende S, Aggarwal NR, Caler EV, Mizgerd JP. Future Research Directions in Pneumonia. NHLBI Working Group Report. Am J Respir Crit Care Med. 2018 07 15; 198(2):256-263.View Related Profiles.

Walkey, Allan
Mizgerd, Joseph

PMID: 29546996; PMCID: PMC6058989; DOI: 10.1164/rccm.201801-0139WS;

Quinton LJ, Walkey AJ, Mizgerd JP. Integrative Physiology of Pneumonia. Physiol Rev. 2018 07 01; 98(3):1417-1464.View Related Profiles.

Walkey, Allan
Mizgerd, Joseph
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PMID: 29767563; PMCID: PMC6088146; DOI: 10.1152/physrev.00032.2017;

Hartmann N, McMurtrey C, Sorensen ML, Huber ME, Kurapova R, Coleman FT, Mizgerd JP, Hildebrand W, Kronenberg M, Lewinsohn DM, Harriff MJ. Riboflavin Metabolism Variation among Clinical Isolates of Streptococcus pneumoniae Results in Differential Activation of Mucosal-associated Invariant T Cells. Am J Respir Cell Mol Biol. 2018 06; 58(6):767-776.View Related Profiles.

Coleman, Fadie
Mizgerd, Joseph

PMID: 29356555; PMCID: PMC6002660; DOI: 10.1165/rcmb.2017-0290OC;

Willinger CM, Rong J, Tanriverdi K, Courchesne PL, Huan T, Wasserman GA, Lin H, Dupuis J, Joehanes R, Jones MR, Chen G, Benjamin EJ, O'Connor GT, Mizgerd JP, Freedman JE, Larson MG, Levy D. MicroRNA Signature of Cigarette Smoking and Evidence for a Putative Causal Role of MicroRNAs in Smoking-Related Inflammation and Target Organ Damage. Circ Cardiovasc Genet. 2017 Oct; 10(5).View Related Profiles.

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Mizgerd, Joseph
Larson, Martin
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PMID: 29030400; PMCID: PMC5683429; DOI: 10.1161/CIRCGENETICS.116.001678;

Wasserman GA, Szymaniak AD, Hinds AC, Yamamoto K, Kamata H, Smith NM, Hilliard KL, Carrieri C, Labadorf AT, Quinton LJ, Ai X, Varelas X, Chen F, Mizgerd JP, Fine A, O'Carroll D, Jones MR. Expression of Piwi protein MIWI2 defines a distinct population of multiciliated cells. J Clin Invest. 2017 Oct 02; 127(10):3866-3876.View Related Profiles.

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Yamamoto, Kazuko
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Quinton, Lee
Jones, Matthew
Varelas, Xaralabos
Ai, Xingbin

PMID: 28920925; PMCID: PMC5617666; DOI: 10.1172/JCI94639;

Coleman FT, Blahna MT, Kamata H, Yamamoto K, Zabinski MC, Kramnik I, Wilson AA, Kotton DN, Quinton LJ, Jones MR, Pelton SI, Mizgerd JP. Capacity of Pneumococci to Activate Macrophage Nuclear Factor ?B: Influence on Necroptosis and Pneumonia Severity. J Infect Dis. 2017 Aug 15; 216(4):425-435.View Related Profiles.

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Yamamoto, Kazuko
Quinton, Lee
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Pelton, Stephen

PMID: 28368460; PMCID: PMC6279164; DOI: 10.1093/infdis/jix159;

Kasotakis G, Galvan MD, Osathanugrah P, Dharia N, Bufe L, Breed Z, Mizgerd JP, Remick DG. Timing of valproic acid in acute lung injury: prevention is the best therapy? J Surg Res. 2017 Dec; 220:206-212.View Related Profiles.

Remick, Daniel
Kasotakis, George
Mizgerd, Joseph

PMID: 29180183; PMCID: PMC5726455; DOI: 10.1016/j.jss.2017.06.088;

Kozlowski E, Wasserman GA, Morgan M, O'Carroll D, Ramirez NP, Gummuluru S, Rah JY, Gower AC, Ieong M, Quinton LJ, Mizgerd JP, Jones MR. The RNA uridyltransferase Zcchc6 is expressed in macrophages and impacts innate immune responses. PLoS One. 2017; 12(6):e0179797.View Related Profiles.

Gower, Adam
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Wasserman, Gregory
Mizgerd, Joseph
Quinton, Lee
Jones, Matthew
Ieong, Michael
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PMID: 28665939; PMCID: PMC5493306; DOI: 10.1371/journal.pone.0179797;

Traber KE, Symer EM, Allen E, Kim Y, Hilliard KL, Wasserman GA, Stewart CL, Jones MR, Mizgerd JP, Quinton LJ. Myeloid-epithelial cross talk coordinates synthesis of the tissue-protective cytokine leukemia inhibitory factor during pneumonia. Am J Physiol Lung Cell Mol Physiol. 2017 Sep 01; 313(3):L548-L558.View Related Profiles.

Wasserman, Gregory
Mizgerd, Joseph
Traber, Katrina
Hilliard, Kristie
Quinton, Lee
Jones, Matthew
Kim, Yuri

PMID: 28522567; PMCID: PMC5625259; DOI: 10.1152/ajplung.00482.2016;

Smith NM, Wasserman GA, Coleman FT, Hilliard KL, Yamamoto K, Lipsitz E, Malley R, Dooms H, Jones MR, Quinton LJ, Mizgerd JP. Regionally compartmentalized resident memory T cells mediate naturally acquired protection against pneumococcal pneumonia. Mucosal Immunol. 2018 Jan; 11(1):220-235.View Related Profiles.

Coleman, Fadie
Wasserman, Gregory
Dooms, Hans
Mizgerd, Joseph
Yamamoto, Kazuko
Hilliard, Kristie
Quinton, Lee
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PMID: 28513594; PMCID: PMC5693795; DOI: 10.1038/mi.2017.43;

Mizgerd JP. Pathogenesis of severe pneumonia: advances and knowledge gaps. Curr Opin Pulm Med. 2017 05; 23(3):193-197. PMID: 28221171; PMCID: PMC5492380; DOI: 10.1097/MCP.0000000000000365;

Kasotakis G, Galvan M, King E, Sarkar B, Stucchi A, Mizgerd JP, Burke PA, Remick D. Valproic acid mitigates the inflammatory response and prevents acute respiratory distress syndrome in a murine model of Escherichia coli pneumonia at the expense of bacterial clearance. J Trauma Acute Care Surg. 2017 Apr; 82(4):758-765.View Related Profiles.

Sarkar, Bedabrata
Remick, Daniel
King, Elizabeth
Kasotakis, George
Mizgerd, Joseph
Burke, Peter

PMID: 28099388; PMCID: PMC5360476; DOI: 10.1097/TA.0000000000001389;

Gutiérrez-Vázquez C, Enright AJ, Rodríguez-Galán A, Pérez-García A, Collier P, Jones MR, Benes V, Mizgerd JP, Mittelbrunn M, Ramiro AR, Sánchez-Madrid F. 3' Uridylation controls mature microRNA turnover during CD4 T-cell activation. RNA. 2017 Jun; 23(6):882-891.View Related Profiles.

Mizgerd, Joseph
Jones, Matthew

PMID: 28351886; PMCID: PMC5435861; DOI: 10.1261/rna.060095.116;

Coleman FT, Blahna MT, Kamata H, Yamamoto K, Zabinski MC, Kramnik I, Wilson AA, Kotton DN, Quinton LJ, Jones MR, Pelton SI, Mizgerd JP. The capacity of pneumococci to activate macrophage NF-kB determines necroptosis and pneumonia severity. The Journal of Infectious Diseases. 2017; 216(4). View Publication

Kamata H, Yamamoto K, Wasserman GA, Zabinski MC, Yuen CK, Lung WY, Gower AC, Belkina AC, Ramirez MI, Deng JC, Quinton LJ, Jones MR, Mizgerd JP. Epithelial Cell-Derived Secreted and Transmembrane 1a Signals to Activated Neutrophils during Pneumococcal Pneumonia. Am J Respir Cell Mol Biol. 2016 Sep; 55(3):407-18.View Related Profiles.

Gower, Adam
Belkina, Anna
Wasserman, Gregory
Mizgerd, Joseph
Yamamoto, Kazuko
Quinton, Lee
Ramirez, Maria
Jones, Matthew

PMID: 27064756; PMCID: PMC5023025; DOI: 10.1165/rcmb.2015-0261OC;

Stanford EA, Ramirez-Cardenas A, Wang Z, Novikov O, Alamoud K, Koutrakis P, Mizgerd JP, Genco CA, Kukuruzinska M, Monti S, Bais MV, Sherr DH. Role for the Aryl Hydrocarbon Receptor and Diverse Ligands in Oral Squamous Cell Carcinoma Migration and Tumorigenesis. Mol Cancer Res. 2016 Aug; 14(8):696-706.View Related Profiles.

Sherr, David
Stanford, Elizabeth
Mizgerd, Joseph
Bais, Manish
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Novikov, Olga
Monti, Stefano
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PMID: 27130942; PMCID: PMC4987205; DOI: 10.1158/1541-7786.MCR-16-0069;

Mizgerd JP. Community-Acquired Pneumonia Requiring Hospitalization. N Engl J Med. 2015 Dec 10; 373(24):2380. PMID: 26650160; DOI: 10.1056/NEJMc1511751#SA1;

Traber KE, Hilliard KL, Allen E, Wasserman GA, Yamamoto K, Jones MR, Mizgerd JP, Quinton LJ. Induction of STAT3-Dependent CXCL5 Expression and Neutrophil Recruitment by Oncostatin-M during Pneumonia. Am J Respir Cell Mol Biol. 2015 Oct; 53(4):479-88.View Related Profiles.

Wasserman, Gregory
Mizgerd, Joseph
Traber, Katrina
Yamamoto, Kazuko
Hilliard, Kristie
Quinton, Lee
Jones, Matthew

PMID: 25692402; PMCID: PMC4742898; DOI: 10.1165/rcmb.2014-0342OC;

Hilliard KL, Allen E, Traber KE, Yamamoto K, Stauffer NM, Wasserman GA, Jones MR, Mizgerd JP, Quinton LJ. The Lung-Liver Axis: A Requirement for Maximal Innate Immunity and Hepatoprotection during Pneumonia. Am J Respir Cell Mol Biol. 2015 Sep; 53(3):378-90.View Related Profiles.

Wasserman, Gregory
Mizgerd, Joseph
Traber, Katrina
Yamamoto, Kazuko
Hilliard, Kristie
Quinton, Lee
Jones, Matthew
Stauffer, Nicole

PMID: 25607543; PMCID: PMC4566062; DOI: 10.1165/rcmb.2014-0195OC;

Hilliard KL, Allen E, Traber KE, Kim Y, Wasserman GA, Jones MR, Mizgerd JP, Quinton LJ. Activation of Hepatic STAT3 Maintains Pulmonary Defense during Endotoxemia. Infect Immun. 2015 Oct; 83(10):4015-27.View Related Profiles.

Wasserman, Gregory
Mizgerd, Joseph
Traber, Katrina
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Quinton, Lee
Jones, Matthew
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PMID: 26216424; PMCID: PMC4567648; DOI: 10.1128/IAI.00464-15;

Mizgerd JP. The infant nose. Introducing the respiratory tract to the world. Am J Respir Crit Care Med. 2014 Dec 1; 190(11):1206-7. PMID: 25436779; PMCID: PMC4315821; DOI: 10.1164/rccm.201410-1919ED;

Hyatt LD, Wasserman GA, Rah YJ, Matsuura KY, Coleman FT, Hilliard KL, Pepper-Cunningham ZA, Ieong M, Stumpo DJ, Blackshear PJ, Quinton LJ, Mizgerd JP, Jones MR. Myeloid ZFP36L1 does not regulate inflammation or host defense in mouse models of acute bacterial infection. PLoS One. 2014; 9(10):e109072.View Related Profiles.

Coleman, Fadie
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Hilliard, Kristie
Quinton, Lee
Jones, Matthew
Ieong, Michael

PMID: 25299049; PMCID: PMC4192124; DOI: 10.1371/journal.pone.0109072;

Quinton LJ, Mizgerd JP. Dynamics of lung defense in pneumonia: resistance, resilience, and remodeling. Annu Rev Physiol. 2015; 77:407-30.View Related Profiles.

Mizgerd, Joseph
Quinton, Lee

PMID: 25148693; PMCID: PMC4366440; DOI: 10.1146/annurev-physiol-021014-071937;

Yamamoto K, Ahyi AN, Pepper-Cunningham ZA, Ferrari JD, Wilson AA, Jones MR, Quinton LJ, Mizgerd JP. Roles of lung epithelium in neutrophil recruitment during pneumococcal pneumonia. Am J Respir Cell Mol Biol. 2014 Feb; 50(2):253-62.View Related Profiles.

Wilson, Andrew
Ahyi, Ayele-Nati
Mizgerd, Joseph
Yamamoto, Kazuko
Quinton, Lee
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PMID: 24010952; PMCID: PMC3930948; DOI: 10.1165/rcmb.2013-0114OC;

Ubags ND, Vernooy JH, Burg E, Hayes C, Bement J, Dilli E, Zabeau L, Abraham E, Poch KR, Nick JA, Dienz O, Zuñiga J, Wargo MJ, Mizgerd JP, Tavernier J, Rincón M, Poynter ME, Wouters EF, Suratt BT. The role of leptin in the development of pulmonary neutrophilia in infection and acute lung injury. Crit Care Med. 2014 Feb; 42(2):e143-51.View Related Profiles.

Hayes, Catherine
Mizgerd, Joseph

PMID: 24231757; PMCID: PMC3947045; DOI: 10.1097/CCM.0000000000000048;

Ahyi AN, Quinton LJ, Jones MR, Ferrari JD, Pepper-Cunningham ZA, Mella JR, Remick DG, Mizgerd JP. Roles of STAT3 in protein secretion pathways during the acute-phase response. Infect Immun. 2013 May; 81(5):1644-53.View Related Profiles.

Ahyi, Ayele-Nati
Remick, Daniel
Mizgerd, Joseph
Mella, Juan
Quinton, Lee
Jones, Matthew

PMID: 23460517; PMCID: PMC3647986; DOI: 10.1128/IAI.01332-12;

Zhang H, Neuhöfer P, Song L, Rabe B, Lesina M, Kurkowski MU, Treiber M, Wartmann T, Regnér S, Thorlacius H, Saur D, Weirich G, Yoshimura A, Halangk W, Mizgerd JP, Schmid RM, Rose-John S, Algül H. IL-6 trans-signaling promotes pancreatitis-associated lung injury and lethality. J Clin Invest. 2013 Mar 1; 123(3):1019-31. PMID: 23426178; PMCID: PMC3582130; DOI: 10.1172/JCI64931;

Wilson AA, Kwok LW, Porter EL, Payne JG, McElroy GS, Ohle SJ, Greenhill SR, Blahna MT, Yamamoto K, Jean JC, Mizgerd JP, Kotton DN. Lentiviral delivery of RNAi for in vivo lineage-specific modulation of gene expression in mouse lung macrophages. Mol Ther. 2013 Apr; 21(4):825-33.View Related Profiles.

Wilson, Andrew
Kotton, Darrell
Mizgerd, Joseph
Jean, Jyh-Chang
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PMID: 23403494; PMCID: PMC3616534; DOI: 10.1038/mt.2013.19;

Quinton LJ, Mizgerd JP. Mucosal Immunology of Acute Bacterial Pneumonia. Transcriptional Signaling Hubs in Epithelial Cells During Pneumonia. 2013; 159-183. View Publication

Stanya KJ, Jacobi D, Liu S, Bhargava P, Dai L, Gangl MR, Inouye K, Barlow JL, Ji Y, Mizgerd JP, Qi L, Shi H, McKenzie AN, Lee CH. Direct control of hepatic glucose production by interleukin-13 in mice. J Clin Invest. 2013 Jan 2; 123(1):261-71. PMID: 23257358; PMCID: PMC3533296; DOI: 10.1172/JCI64941;

Jones MR, Blahna MT, Kozlowski E, Matsuura KY, Ferrari JD, Morris SA, Powers JT, Daley GQ, Quinton LJ, Mizgerd JP. Zcchc11 uridylates mature miRNAs to enhance neonatal IGF-1 expression, growth, and survival. PLoS Genet. 2012; 8(11):e1003105.View Related Profiles.

Kozlowski, Elyse
Mizgerd, Joseph
Quinton, Lee
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PMID: 23209448; PMCID: PMC3510031; DOI: 10.1371/journal.pgen.1003105;

Bartlett NW, Slater L, Glanville N, Haas JJ, Caramori G, Casolari P, Clarke DL, Message SD, Aniscenko J, Kebadze T, Zhu J, Mallia P, Mizgerd JP, Belvisi M, Papi A, Kotenko SV, Johnston SL, Edwards MR. Defining critical roles for NF-?B p65 and type I interferon in innate immunity to rhinovirus. EMBO Mol Med. 2012 Dec; 4(12):1244-60. PMID: 23165884; PMCID: PMC3531601; DOI: 10.1002/emmm.201201650;

Yamamoto K, Ferrari JD, Cao Y, Ramirez MI, Jones MR, Quinton LJ, Mizgerd JP. Type I alveolar epithelial cells mount innate immune responses during pneumococcal pneumonia. J Immunol. 2012 Sep 1; 189(5):2450-9.View Related Profiles.

Mizgerd, Joseph
Yamamoto, Kazuko
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Ramirez, Maria
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Cao, Yu-Xia

PMID: 22844121; PMCID: PMC3424336; DOI: 10.4049/jimmunol.1200634;

Mizgerd JP. Respiratory infection and the impact of pulmonary immunity on lung health and disease. Am J Respir Crit Care Med. 2012 Nov 1; 186(9):824-9. PMID: 22798317; PMCID: PMC3530220; DOI: 10.1164/rccm.201206-1063PP;

Quinton LJ, Mizgerd JP, Hilliard KL, Jones MR, Kwon CY, Allen E. Leukemia inhibitory factor signaling is required for lung protection during pneumonia. J Immunol. 2012 Jun 15; 188(12):6300-8.View Related Profiles.

Mizgerd, Joseph
Hilliard, Kristie
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PMID: 22581855; PMCID: PMC3370070; DOI: 10.4049/jimmunol.1200256;

Quinton LJ, Blahna MT, Jones MR, Allen E, Ferrari JD, Hilliard KL, Zhang X, Sabharwal V, Algül H, Akira S, Schmid RM, Pelton SI, Spira A, Mizgerd JP. Hepatocyte-specific mutation of both NF-?B RelA and STAT3 abrogates the acute phase response in mice. J Clin Invest. 2012 May 1; 122(5):1758-63.View Related Profiles.

Spira, Avrum
Mizgerd, Joseph
Hilliard, Kristie
Quinton, Lee
Jones, Matthew
Pelton, Stephen
Sabharwal, Vishakha
Zhang, Xiaoling

PMID: 22466650; PMCID: PMC3336975; DOI: 10.1172/JCI59408;

Hyatt LD, Matsuura KM, Joo Rah Y, Pepper-Cunningham ZA, Ferrari JD, Quinton LJ, Mizgerd JP, Jones MR. American Thoracic Society 2012 International Conference. Myeloid Deficiency Of Brf1 Limits Inflammatory Cytokine MRNA Expression During Pneumonia. 2012. View Publication
Coleman FT, Blahna MT, Ferrari JD, Pepper-Cunningham ZA, Yamamoto K, Wilson AA, Quinton LJ, Jones MR, Kotton DN, Pelton SI, Mizgerd JP. American Thoracic Society 2012 International Conference. Heterogeneity In Activation Of Macrophage NF-?B By Patient Isolates Of Pneumococci. 2012. View Publication
Ahyi ANN, Quinton LJ, Jones MR, Ferrari JD, Shen S, Spira A, Mizgerd JP. American Thoracic Society 2012 International Conference. Stat3 Mediates Secretory Protein Expression In The Liver During Pneumonia And ER Stress. 2012. View Publication
Chinthrajah RS, Govender P, Ferrari JP, Yamamoto K, Ahyi ANN, White MR, Pepper-Cunningham Z, Hartshorn K, Quinton LJ, Mizgerd JP. The Acute Phase Response Limits Inflammatory Cytokine Expression During Influenza Infection. American Thoracic Society 2012 International Conference. 2012. View Publication
Govender P, Yamamoto K, Ferrari JD, Chinthrajah RS, Pepper-Cunningham ZA, Ahyi ANN, Jones MR, Quinton LJ, Mizgerd JP. American Thoracic Society 2012 International Conference. An Essential Role For Myeloid RelA In Basal Lung Homeostasis. 2012. View Publication
Hilliard K, Mizgerd JP, Allen E, Jones MR, Quinton LJ. American Thoracic Society 2012 International Conference. The Hepatic Acute Phase Response Regulates Pulmonary Inflammation During Pneumonia. 2012. View Publication
Hong Z, Neuhofer P, Liang S, Rabe B, Lesina M, Kurkowski MU, Treiber M, Wartmann T, Regner S, Thorlacius H, Saur D, Yoshimura A, Halangk W, Mizgerd JP, Rose-John S, Schmid RM, Algul H. IL-6 Trans-signaling vermittelt über die Aktivierung von Stat3 das letale Lungenversagen der schweren akuten Pankreatitis. Zeitschrift für Gastroenterologie. 2012; 50(8). View Publication

Blahna MT, Jones MR, Quinton LJ, Matsuura KY, Mizgerd JP. Terminal uridyltransferase enzyme Zcchc11 promotes cell proliferation independent of its uridyltransferase activity. J Biol Chem. 2011 Dec 9; 286(49):42381-9.View Related Profiles.

Mizgerd, Joseph
Quinton, Lee
Jones, Matthew

PMID: 22006926; PMCID: PMC3234974; DOI: 10.1074/jbc.M111.259689;

Pittet LA, Quinton LJ, Yamamoto K, Robson BE, Ferrari JD, Algül H, Schmid RM, Mizgerd JP. Earliest innate immune responses require macrophage RelA during pneumococcal pneumonia. Am J Respir Cell Mol Biol. 2011 Sep; 45(3):573-81.View Related Profiles.

Mizgerd, Joseph
Yamamoto, Kazuko
Quinton, Lee

PMID: 21216972; PMCID: PMC3175578; DOI: 10.1165/rcmb.2010-0210OC;

Blahna MT, Jones MR, Quinton LJ, Mizgerd JP. American Thoracic Society 2011 International Conference. Zcchc11 Enhances Cellular Proliferation Independent Of Its Uridyltransferase Activity. 2011. View Publication
Ferrari JD, Yamamoto K, Blahna MT, Quinton LJ, Jones MR, Mizgerd JP. American Thoracic Society 2011 International Conference. Distinct Roles Of NF-?B RelA In Mediating Cytokine Expression From Type I And Type II Cells In The Lung. 2011. View Publication
Yamamoto K, Blahna MT, Ferrari JD, Jones MR, Quinton LJ, Mizgerd JP. American Thoracic Society 2011 International Conference. Neutrophils Are Sources Of Lung Cytokines With Distinct Transcription Factor Regulation During Pneumonia. 2011. View Publication
Coleman FT, Blahna MT, Ferrari JD, Yamamoto K, Wilson AA, Quinton LJ, Jones MR, Kotton DN, Pelton SI, Mizgerd JP. American Thoracic Society 2011 International Conference. Avoiding Or Subverting Macrophage NF-?B Activation As A Virulence Mechanism Of Invasive Pneumococci. 2011. View Publication
Chinthrajah RS, Govender P, Allen E, Ferrarri JD, Matsuura K, Jones MR, Hartshorn K, Quinton LJ, Mizgerd JP. American Thoracic Society 2011 International Conference. Influenza Pneumonia And The Hepatic Acute Phase Response. 2011. View Publication
Govender P, Chinthrajah RS, White MR, Blahna MT, Ferrari JD, Quinton LJ, Hartshorn K, Mizgerd JP. American Thoracic Society 2011 International Conference. Roles Of NF-kappaB RelA In Myeloid Cells During Influenza Infection. 2011. View Publication
Quinton LJ, Mizgerd JP, Jones MR, Allen E. American Journal of Respiratory and Critical Care Medicine. Endogenous Leukemia Inhibitory Factor Limits Acute Lung Injury During Pneumonia. 2011; 183. View Publication
Ahyi ANN, Quinton LJ, Ferrari JD, Shen S, Jones MR, Spira A, Mizgerd JP. American Thoracic Society 2011 International Conference. Stat3 Is A Key Regulator Of Secretory Protein Expression During Pneumonia-Induced Acute Phase Response And Er Stress. 2011. View Publication

Perrone LA, Szretter KJ, Katz JM, Mizgerd JP, Tumpey TM. Mice lacking both TNF and IL-1 receptors exhibit reduced lung inflammation and delay in onset of death following infection with a highly virulent H5N1 virus. J Infect Dis. 2010 Oct 15; 202(8):1161-70. PMID: 20815704; PMCID: PMC2941567; DOI: 10.1086/656365;

Quinton LJ, Mizgerd JP. NF-?B and STAT3 signaling hubs for lung innate immunity. Cell Tissue Res. 2011 Jan; 343(1):153-65.View Related Profiles.

Mizgerd, Joseph
Quinton, Lee

PMID: 20872151; DOI: 10.1007/s00441-010-1044-y;

Blahna MT, Jones MR, Quinton LJ, Mizgerd JP. The Uridyl-Transferase Enzyme Zcchc11 Prevents Senescence And Promotes Cellular Proliferation. American Thoracic Society 2010 International Conference. 2010. View Publication
Quinton LJ, Blahna MT, Jones MR, Allen E, Ferrari JD, Zhang X, Spira A, Mizgerd JP. A Novel Acute Phase-null Mouse Reveals A Critical Role For Liver Products During Pneumonia. American Thoracic Society 2010 International Conference. 2010. View Publication
Ahyi ANN, Quinton LJ, Ferrari D, Shen S, Spira A, Mizgerd JP. American Thoracic Society 2010 International Conference. Protein Secretory Pathway Induction Is Part Of The Acute Phase Response During Pneumonia. 2010. View Publication

Jones MR, Quinton LJ, Blahna MT, Neilson JR, Fu S, Ivanov AR, Wolf DA, Mizgerd JP. Zcchc11-dependent uridylation of microRNA directs cytokine expression. Nat Cell Biol. 2009 Sep; 11(9):1157-63.View Related Profiles.

Mizgerd, Joseph
Quinton, Lee
Jones, Matthew

PMID: 19701194; PMCID: PMC2759306; DOI: 10.1038/ncb1931;

Quinton LJ, Jones MR, Robson BE, Mizgerd JP. Mechanisms of the hepatic acute-phase response during bacterial pneumonia. Infect Immun. 2009 Jun; 77(6):2417-26.View Related Profiles.

Mizgerd, Joseph
Quinton, Lee
Jones, Matthew

PMID: 19289507; PMCID: PMC2687329; DOI: 10.1128/IAI.01300-08;

Li Y, Jia Y, Pichavant M, Loison F, Sarraj B, Kasorn A, You J, Robson BE, Umetsu DT, Mizgerd JP, Ye K, Luo HR. Targeted deletion of tumor suppressor PTEN augments neutrophil function and enhances host defense in neutropenia-associated pneumonia. Blood. 2009 May 14; 113(20):4930-41.View Related Profiles.

Mizgerd, Joseph
Jia, Yonghui

PMID: 19286998; PMCID: PMC2686143; DOI: 10.1182/blood-2008-06-161414;

Gamble L, Bagby GJ, Quinton LJ, Happel KI, Mizgerd JP, Zhang P, Nelson S. The systemic and pulmonary LPS binding protein response to intratracheal lipopolysaccharide. Shock. 2009 Feb; 31(2):212-7.View Related Profiles.

Mizgerd, Joseph
Quinton, Lee

PMID: 18520704; DOI: 10.1097/SHK.0b013e31817c0d7d;

Pittet LA, Quinton LJ, Robson BE, Ferrari JD, Algul H, Schmid RM, Mizgerd JP. American Thoracic Society 2009 International Conference. NF-?B RelA Deficiency in Macrophages Delays Response to Pneumococcal Pneumonia. 2009. View Publication
Quinton LJ, Jones MR, Robson BE, Mizgerd JP. American Thoracic Society 2009 International Conference. Signaling Networks Mediating the Hepatic Acute Phase Response during Bacterial Pneumonia. 2009. View Publication
Jones MR, Quinton LJ, Blahna MT, Mizgerd JP. American Thoracic Society 2009 International Conference. Uridylation of mir-26b Enhances IL-6 Expression. 2009. View Publication
Blahna MT, Jones MR, Quinton LJ, Mizgerd JP. American Thoracic Society 2009 International Conference. Prevention of Cellular Senescence by the Uridyl Transferase Enzyme Zcchc11. 2009. View Publication

Huang Y, Zhang J, McHenry KT, Kim MM, Zeng W, Lopez-Pajares V, Dibble CC, Mizgerd JP, Yuan ZM. Induction of cytoplasmic accumulation of p53: a mechanism for low levels of arsenic exposure to predispose cells for malignant transformation. Cancer Res. 2008 Nov 15; 68(22):9131-6. PMID: 19010883; PMCID: PMC2717853; DOI: 10.1158/0008-5472.CAN-08-3025;

Lang JE, Williams ES, Mizgerd JP, Shore SA. Effect of obesity on pulmonary inflammation induced by acute ozone exposure: role of interleukin-6. Am J Physiol Lung Cell Mol Physiol. 2008 May; 294(5):L1013-20. PMID: 18359888; DOI: 10.1152/ajplung.00122.2007;

Mizgerd JP. Acute lower respiratory tract infection. N Engl J Med. 2008 Feb 14; 358(7):716-27. PMID: 18272895; PMCID: PMC2711392; DOI: 10.1056/NEJMra074111;

Quinton LJ, Jones MR, Robson BE, Simms BT, Whitsett JA, Mizgerd JP. Alveolar epithelial STAT3, IL-6 family cytokines, and host defense during Escherichia coli pneumonia. Am J Respir Cell Mol Biol. 2008 Jun; 38(6):699-706.View Related Profiles.

Mizgerd, Joseph
Quinton, Lee
Jones, Matthew

PMID: 18192501; PMCID: PMC2396249; DOI: 10.1165/rcmb.2007-0365OC;

Mizgerd JP, Skerrett SJ. Animal models of human pneumonia. Am J Physiol Lung Cell Mol Physiol. 2008 Mar; 294(3):L387-98. PMID: 18162603

Johnston RA, Mizgerd JP, Flynt L, Quinton LJ, Williams ES, Shore SA. Type I interleukin-1 receptor is required for pulmonary responses to subacute ozone exposure in mice. Am J Respir Cell Mol Biol. 2007 Oct; 37(4):477-84.View Related Profiles.

Mizgerd, Joseph
Quinton, Lee

PMID: 17575079; PMCID: PMC2176124; DOI: 10.1165/rcmb.2006-0315OC;

Quinton LJ, Jones MR, Simms BT, Kogan MS, Robson BE, Skerrett SJ, Mizgerd JP. Functions and regulation of NF-kappaB RelA during pneumococcal pneumonia. J Immunol. 2007 Feb 1; 178(3):1896-903.View Related Profiles.

Mizgerd, Joseph
Quinton, Lee
Jones, Matthew

PMID: 17237440; PMCID: PMC2674289; DOI: 10.4049/jimmunol.178.3.1896;

Nakahira M, Tanaka T, Robson BE, Mizgerd JP, Grusby MJ. Regulation of signal transducer and activator of transcription signaling by the tyrosine phosphatase PTP-BL. Immunity. 2007 Feb; 26(2):163-76. PMID: 17306571

Subramanian KK, Jia Y, Zhu D, Simms BT, Jo H, Hattori H, You J, Mizgerd JP, Luo HR. Tumor suppressor PTEN is a physiologic suppressor of chemoattractant-mediated neutrophil functions. Blood. 2007 May 1; 109(9):4028-37.View Related Profiles.

Mizgerd, Joseph
Jia, Yonghui

PMID: 17202315; PMCID: PMC1874585; DOI: 10.1182/blood-2006-10-055319;

Yano K, Liaw PC, Mullington JM, Shih SC, Okada H, Bodyak N, Kang PM, Toltl L, Belikoff B, Buras J, Simms BT, Mizgerd JP, Carmeliet P, Karumanchi SA, Aird WC. Vascular endothelial growth factor is an important determinant of sepsis morbidity and mortality. J Exp Med. 2006 Jun 12; 203(6):1447-58. PMID: 16702604; PMCID: PMC2118329; DOI: 10.1084/jem.20060375;

Prince AS, Mizgerd JP, Wiener-Kronish J, Bhattacharya J. Cell signaling underlying the pathophysiology of pneumonia. Am J Physiol Lung Cell Mol Physiol. 2006 Sep; 291(3):L297-300. PMID: 16648241

Krishnamurthy VM, Quinton LJ, Estroff LA, Metallo SJ, Isaacs JM, Mizgerd JP, Whitesides GM. Promotion of opsonization by antibodies and phagocytosis of Gram-positive bacteria by a bifunctional polyacrylamide. Biomaterials. 2006 Jul; 27(19):3663-74.View Related Profiles.

Mizgerd, Joseph
Quinton, Lee

PMID: 16527349

Mizgerd JP. Lung infection--a public health priority. PLoS Med. 2006 Feb; 3(2):e76. PMID: 16401173; PMCID: PMC1326257; DOI: 10.1371/journal.pmed.0030076;

Jones MR, Quinton LJ, Simms BT, Lupa MM, Kogan MS, Mizgerd JP. Roles of interleukin-6 in activation of STAT proteins and recruitment of neutrophils during Escherichia coli pneumonia. J Infect Dis. 2006 Feb 1; 193(3):360-9.View Related Profiles.

Mizgerd, Joseph
Quinton, Lee
Jones, Matthew

PMID: 16388483; PMCID: PMC2674298; DOI: 10.1086/499312;

Jones MR, Simms BT, Lupa MM, Kogan MS, Mizgerd JP. Lung NF-kappaB activation and neutrophil recruitment require IL-1 and TNF receptor signaling during pneumococcal pneumonia. J Immunol. 2005 Dec 1; 175(11):7530-5.View Related Profiles.

Mizgerd, Joseph
Jones, Matthew

PMID: 16301661; PMCID: PMC2723739; DOI: 10.4049/jimmunol.175.11.7530;

Faffe DS, Flynt L, Mellema M, Moore PE, Silverman ES, Subramaniam V, Jones MR, Mizgerd JP, Whitehead T, Imrich A, Panettieri RA, Shore SA. Oncostatin M causes eotaxin-1 release from airway smooth muscle: synergy with IL-4 and IL-13. J Allergy Clin Immunol. 2005 Mar; 115(3):514-20.View Related Profiles.

Mizgerd, Joseph
Jones, Matthew

PMID: 15753898

Johnston RA, Mizgerd JP, Shore SA. CXCR2 is essential for maximal neutrophil recruitment and methacholine responsiveness after ozone exposure. Am J Physiol Lung Cell Mol Physiol. 2005 Jan; 288(1):L61-7. PMID: 15361358

Mizgerd JP, Lupa MM, Spieker MS. NF-kappaB p50 facilitates neutrophil accumulation during LPS-induced pulmonary inflammation. BMC Immunol. 2004 Jun 9; 5:10. PMID: 15189567; PMCID: PMC449706

Mizgerd JP, Lupa MM, Hjoberg J, Vallone JC, Warren HB, Butler JP, Silverman ES. Roles for early response cytokines during Escherichia coli pneumonia revealed by mice with combined deficiencies of all signaling receptors for TNF and IL-1. Am J Physiol Lung Cell Mol Physiol. 2004 Jun; 286(6):L1302-10. PMID: 14966082

Wang Q, Doerschuk CM, Mizgerd JP. Neutrophils in innate immunity. Semin Respir Crit Care Med. 2004 Feb; 25(1):33-41. PMID: 16088447

Mizgerd JP. Competing benefits of tumor necrosis factor-alpha for bacteria and for host defense. Am J Respir Crit Care Med. 2003 Dec 15; 168(12):1410-1. PMID: 14668252

Mizgerd JP, Lupa MM, Kogan MS, Warren HB, Kobzik L, Topulos GP. Nuclear factor-kappaB p50 limits inflammation and prevents lung injury during Escherichia coli pneumonia. Am J Respir Crit Care Med. 2003 Oct 1; 168(7):810-7. PMID: 12857723

Mizgerd JP, Spieker MR, Lupa MM. Exon truncation by alternative splicing of murine ICAM-1. Physiol Genomics. 2002 Dec 26; 12(1):47-51. PMID: 12407184

Mizgerd JP, Scott ML, Spieker MR, Doerschuk CM. Functions of IkappaB proteins in inflammatory responses to Escherichia coli LPS in mouse lungs. Am J Respir Cell Mol Biol. 2002 Nov; 27(5):575-82. PMID: 12397017

Tasaka S, Richer SE, Mizgerd JP, Doerschuk CM. Very late antigen-4 in CD18-independent neutrophil emigration during acute bacterial pneumonia in mice. Am J Respir Crit Care Med. 2002 Jul 1; 166(1):53-60. PMID: 12091171

Mizgerd JP. Molecular mechanisms of neutrophil recruitment elicited by bacteria in the lungs. Semin Immunol. 2002 Apr; 14(2):123-32. PMID: 11978084

Alcamo E, Mizgerd JP, Horwitz BH, Bronson R, Beg AA, Scott M, Doerschuk CM, Hynes RO, Baltimore D. Targeted mutation of TNF receptor I rescues the RelA-deficient mouse and reveals a critical role for NF-kappa B in leukocyte recruitment. J Immunol. 2001 Aug 1; 167(3):1592-600. PMID: 11466381

Huang C, De Sanctis GT, O'Brien PJ, Mizgerd JP, Friend DS, Drazen JM, Brass LF, Stevens RL. Evaluation of the substrate specificity of human mast cell tryptase beta I and demonstration of its importance in bacterial infections of the lung. J Biol Chem. 2001 Jul 13; 276(28):26276-84.View Related Profiles.

Drazen, Jeffrey
Mizgerd, Joseph

PMID: 11335723

Mizgerd JP, Spieker MR, Doerschuk CM. Early response cytokines and innate immunity: essential roles for TNF receptor 1 and type I IL-1 receptor during Escherichia coli pneumonia in mice. J Immunol. 2001 Mar 15; 166(6):4042-8. PMID: 11238652

Horwitz BH, Mizgerd JP, Scott ML, Doerschuk CM. Mechanisms of granulocytosis in the absence of CD18. Blood. 2001 Mar 15; 97(6):1578-83. PMID: 11238094

Mizgerd JP, Peschon JJ, Doerschuk CM. Roles of tumor necrosis factor receptor signaling during murine Escherichia coli pneumonia. Am J Respir Cell Mol Biol. 2000 Jan; 22(1):85-91. PMID: 10615069

Palombo JD, DeMichele SJ, Boyce PJ, Lydon EE, Liu JW, Huang YS, Forse RA, Mizgerd JP, Bistrian BR. Effect of short-term enteral feeding with eicosapentaenoic and gamma-linolenic acids on alveolar macrophage eicosanoid synthesis and bactericidal function in rats. Crit Care Med. 1999 Sep; 27(9):1908-15. PMID: 10507617

Mizgerd JP, Horwitz BH, Quillen HC, Scott ML, Doerschuk CM. Effects of CD18 deficiency on the emigration of murine neutrophils during pneumonia. J Immunol. 1999 Jul 15; 163(2):995-9. PMID: 10395697

Doerschuk CM, Mizgerd JP, Kubo H, Qin L, Kumasaka T. Adhesion molecules and cellular biomechanical changes in acute lung injury: Giles F. Filley Lecture. Chest. 1999 Jul; 116(1 Suppl):37S-43S. PMID: 10424587

Mizgerd JP, Bullard DC, Hicks MJ, Beaudet AL, Doerschuk CM. Chronic inflammatory disease alters adhesion molecule requirements for acute neutrophil emigration in mouse skin. J Immunol. 1999 May 1; 162(9):5444-8. PMID: 10228023

Mizgerd JP, Quinlan WM, LeBlanc BW, Kutkoski GJ, Bullard DC, Beaudet AL, Doerschuk CM. Combinatorial requirements for adhesion molecules in mediating neutrophil emigration during bacterial peritonitis in mice. J Leukoc Biol. 1998 Sep; 64(3):291-7. PMID: 9738654

Bran JD, Molina RM, Mizgerd JP, Warner AE. Mechanism of gadolinium-induced macrophage inactivation. 1998.
Mizgerd JP, Horwitz BH, Bhagwan SD, Scott ML, Beaudet AL, Doerschuk CM. Compromised emigration of CD18-deficient neutrophils during LPS pneumonia in bone marrow chimera mice. 1998.

Mizgerd JP, Kubo H, Kutkoski GJ, Bhagwan SD, Scharffetter-Kochanek K, Beaudet AL, Doerschuk CM. Neutrophil emigration in the skin, lungs, and peritoneum: different requirements for CD11/CD18 revealed by CD18-deficient mice. J Exp Med. 1997 Oct 20; 186(8):1357-64. PMID: 9334375; PMCID: PMC2199087

Mizgerd JP, Meek BB, Kutkoski GJ, Bullard DC, Beaudet AL, Doerschuk CM. Selectins and neutrophil traffic: margination and Streptococcus pneumoniae-induced emigration in murine lungs. J Exp Med. 1996 Aug 1; 184(2):639-45. PMID: 8760817; PMCID: PMC2192708

Mizgerd JP, Molina RM, Stearns RC, Brain JD, Warner AE. Gadolinium induces macrophage apoptosis. J Leukoc Biol. 1996 Feb; 59(2):189-95. PMID: 8603991

Mizgerd JP, Kobzik L, Warner AE, Brain JD. Effects of sodium concentration on human neutrophil bactericidal functions. Am J Physiol. 1995 Sep; 269(3 Pt 1):L388-93. PMID: 7573473

Mizgerd JP, Brain JD. Reactive oxygen species in the killing of Pseudomonas aeruginosa by human leukocytes. Curr Microbiol. 1995 Aug; 31(2):124-8. PMID: 7606187

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 157 publications over 31 distinct years, with a maximum of 14 publications in 2012

Bar chart showing 157 publications over 31 distinct years, with a maximum of 14 publications in 2012

Year	Publications
1995	2
1996	2
1997	1
1998	3
1999	4
2000	1
2001	4
2002	4
2003	2
2004	4
2005	3
2006	4
2007	5
2008	4
2009	8
2010	5
2011	10
2012	14
2013	4
2014	5
2015	4
2016	2
2017	11
2018	4
2019	3
2020	5
2021	11
2022	7
2023	5
2024	7
2025	9

Media Mentions

Viral Sepsis Debate: Real Threat or a Clinical Misdiagnosis?

Medscape 9/29/2025

Kilachand Fund Awards Go to Crystal Rib Cage and Brain Connection Projects

BU Today 10/3/2023

Epithelial Cells Use MHC-II Molecule to Orchestrate Lung Immunity

Genetic & Engineering News 10/6/2021

Scientists tease out role of epithelial cells in lung immunity

Science Board 10/6/2021

How Does Lung Immunity Work? Study Identifies Each Cell That Build Respiratory Immune Response

Science Times 10/6/2021

MED’s Biology of the Lung Funded through Its 50th—Yes, 50th—Year

BU Today 9/23/2021

BU awarded T32 grant to mentor research trainees in lung biology and pulmonary sciences

News Medical 7/1/2021

Coronavirus family now a prime suspect in previous pandemics

Irish Times 2/4/2021

Tonight’s University Lecture: On the Front Lines against COVID in the Lab, Science Will Win

BU Today 11/17/2020

Common Cold Coronaviruses Tied to Less Severe COVID-19 Cases

The Scientist 11/11/2020

Do Colds Offer COVID-19 Protection?

The Doctor Will See You Now 10/22/2020

Research Roundup: COVID-19 Pain Relief and More

BioSpace 10/9/2020

After Infection, Lung Immune Cells Remember For Next Time

Futurity 1/29/2020

2023 American Thoracic Society: Recognition Award for Scientific Accomplishment

2021 BU: Jerome S. Brody, MD, Professor of Pulmonary Medicine

2021 American Thoracic Society: Scientific Accomplishment Award for Allergy, Immunology & Inflammation

2020 BU: University Lecture

2018 American Thoracic Society: ATS Fellow

2017 NIH: NHLBI Outstanding Investigator

2017 BUSM Department of Medicine: Robert Dawson Evans Research Mentoring Award

1999 Francis Families Foundation: Parker B. Francis Fellow in Pulmonary Research

1998 American Lung Association: Edward Livingston Trudeau Scholar

In addition to these self-described keywords below, a list of MeSH based concepts is available here.

acute lower respiratory tract infection
ARDS
cell biology
cytokines
gene expression
immunological memory
innate immunity
lung epithelial cells
lung infection
lung lymphocytes
macrophages
neutrophils
pneumonia
pulmonary immunology

Available to Mentor as: (Review Mentor Role Definitions):

Co-Mentor or Peer Mentor
Diversity Mentor
Research / Scholarly Mentor

Contact for Mentoring:

Email (see 'Contact Info')

72 E. Concord St Housman (R)
Boston MA 02118
Google Map

617.358.1186

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