Esther Bullitt, PhD
Associate Professor
Boston University School of Medicine
Dept of Physiology & Biophysics

PhD, Brandeis University

Pronouns: she/her/hers



Structural studies of biological macromolecular assemblies are providing an understanding of cellular function. In our laboratory, we utilize electron microscopy and image reconstruction to investigate questions about microbial virulence.

Work in the lab currently focuses on bacterial adhesion pili (fimbriae), type III secretion system needles, and virus replication. These projects address basic medical research questions directed at understanding bacterial adhesion to human host tissue and viral replication. Our data support development of novel therapeutics targeting these important health issues including, for example, development of a vaccine against traveler’s diarrhea.

Graduate Faculty (Primary Mentor of Grad Students)
Boston University School of Medicine, Graduate Medical Sciences



2021 Microscopy Society of America: Past-President
2020 Microscopy Society of America: President
2019 Microscopy Society of America: President-elect
2018-pres International Union of Crystallography Journal: Associate Editor


The multiple states of IpaB Shigella type lll secretion
06/02/2014 - 11/30/2018 (Subcontract PI)
University of Kansas NIH NIAID
5R01AI099489-06

Towards the Disruption of Viral RNA Replication
07/01/2012 - 06/30/2017 (PI)
NIH/National Institute of General Medical Sciences
5R01GM102474-04

Measurement of Bacteriophage Lengths using Transmission electron microscopy and image analysis
01/01/2012 - 12/31/2016 (PI)
Neurophage pharmaceuticals, Inc.


Towards the Disruption of Viral RNA Replication
07/01/2012 - 06/30/2016 (PI)
NIH/National Institute of General Medical Sciences
1R01GM102474-01

The multiple states of IpaB Shigella type III secretion
12/04/2012 - 06/01/2014 (Subcontract PI)
University of Oklahoma NIH NIAID
1R01AI099489-01A1



Title


Yr Title Project-Sub Proj Pubs
2019 CryoEM Data Collection Facility Consortium at NCM 5U24GM116787-04 6
2019 Midwest Consortium for High Resolution Cryoelectron Microscopy 5U24GM116789-03 3
2019 The Southeastern Consortium for Microscopy of MacroMolecular Machines 5U24GM116788-04 7
2019 Administrative Supplement: The Southeastern Consortium for Microscopy of MacroMolecular Machines 3U24GM116788-04S1 7
2018 CryoEM Data Collection Facility Consortium at NCM 5U24GM116787-03 6
2018 Midwest Consortium for High Resolution Cryoelectron Microscopy 5U24GM116789-02 3
2018 The Southeastern Consortium for Microscopy of MacroMolecular Machines 5U24GM116788-03 7
2017 CryoEM Data Collection Facility Consortium at NCM 7U24GM116787-02 6
2017 Midwest Consortium for High Resolution Cryoelectron Microscopy 1U24GM116789-01A1 3
2017 The Southeastern Consortium for Microscopy of MacroMolecular Machines 3U24GM116788-02S1 7
Showing 10 of 33 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Huang J, Hume AJ, Abo KM, Werder RB, Villacorta-Martin C, Alysandratos KD, Beermann ML, Simone-Roach C, Olejnik J, Suder EL, Bullitt E, Hinds A, Sharma A, Bosmann M, Wang R, Hawkins F, Burks EJ, Saeed M, Wilson AA, Mühlberger E, Kotton DN. SARS-CoV-2 Infection of Pluripotent Stem Cell-derived Human Lung Alveolar Type 2 Cells Elicits a Rapid Epithelial-Intrinsic Inflammatory Response. bioRxiv. 2020 Jun 30.View Related Profiles. PMID: 32637964
     
  2. Yang JE, Rossignol ED, Chang D, Zaia J, Forrester I, Raja K, Winbigler H, Nicastro D, Jackson WT, Bullitt E. Complexity and ultrastructure of infectious extracellular vesicles from cells infected by non-enveloped virus. Sci Rep. 2020 May 14; 10(1):7939.View Related Profiles. PMID: 32409751
     
  3. Zheng W, Andersson M, Mortezaei N, Bullitt E, Egelman E. Cryo-EM structure of the CFA/I pilus rod. IUCrJ. 2019 Sep 01; 6(Pt 5):815-821. PMID: 31576215
     
  4. Filman DJ, Marino SF, Ward JE, Yang L, Mester Z, Bullitt E, Lovley DR, Strauss M. Cryo-EM reveals the structural basis of long-range electron transport in a cytochrome-based bacterial nanowire. Commun Biol. 2019 Jun 19; 2(1):219. PMID: 31925024
     
  5. Filman DJ, Marino SF, Ward JE, Yang L, Mester Z, Bullitt E, Lovley DR, Strauss M. Cryo-EM reveals the structural basis of long-range electron transport in a cytochrome-based bacterial nanowire. Commun Biol. 2019; 2:219. PMID: 31240257
     
  6. Jie E. Yang, Evan D. Rossignol, Deborah Chang, Joseph Zaia, Isaac Forrester, Holly Saulsbery, Daniela Nicastro, William T. Jackson, Esther Bullitt. Complexity and ultrastructure of infectious extracellular vesicles from cells infected by non-enveloped virus. bioRxiv. 2019. View Publication
  7. Brown JW, Badahdah A, Iticovici M, Vickers TJ, Alvarado DM, Helmerhorst EJ, Oppenheim FG, Mills JC, Ciorba MA, Fleckenstein JM, Bullitt E. A Role for Salivary Peptides in the Innate Defense Against Enterotoxigenic Escherichia coli. J Infect Dis. 2018 04 11; 217(9):1435-1441.View Related Profiles. PMID: 29528423
     
  8. Wiklund K, Zhang H, Stangner T, Singh B, Bullitt E, Andersson M. A drag force interpolation model for capsule-shaped cells in fluid flows near a surface. Microbiology. 2018 04; 164(4):483-494. PMID: 29509130
     
  9. Epler Barbercheck CR, Bullitt E, Andersson M. Bacterial Adhesion Pili. Subcell Biochem. 2018; 87:1-18. PMID: 29464555
     
  10. Rossignol ED, Peters KN, Connor JH, Bullitt E. Zika virus induced cellular remodelling. Cell Microbiol. 2017 Aug; 19(8).View Related Profiles. PMID: 28318141; DOI: 10.1111/cmi.12740;
     
Showing 10 of 51 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 51 publications over 26 distinct years, with a maximum of 4 publications in 2015 and 2019

YearPublications
19851
19861
19881
19921
19951
19962
19971
19982
20001
20022
20042
20062
20073
20082
20092
20102
20113
20123
20133
20141
20154
20161
20171
20183
20194
20202
Contact for Mentoring:

700 Albany St Ctr for Adv Biomed Res
Boston MA 02118
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