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PhD, Universität Konstanz
MS, Universität Konstanz
BS, Universität Konstanz

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	Whitaker Cardiovascular Institute Training Program
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ORCID : 0000-0002-0748-5528

BU Research
NIH RePORTER Research

Redox Control of Hepatic Lipid Metabolism
07/01/2015 - 04/30/2020 (PI)
NIH/National Diabetes & Digestive & Kidney Diseases
5R01DK103750-05

Impaired cysteine-thiol redox signaling in metabolic cardiovascular disease
01/01/2016 - 12/31/2018 (PI)
American Heart Association

Regulation of the Cardiac Sodium Channel by SIRTUIN1
06/01/2016 - 05/31/2017 (Subcontract PI)
The University of Iowa NIH NHLBI
4R01HL115955-04

Regulation of the Cardiac Sodium Channel by SIRTUIN1
08/15/2013 - 05/31/2017 (Subcontract PI)
The University of Iowa NIH NHLBI
5R01HL115955-03

Title

Yr	Title	Project-Sub Proj	Pubs
2019	Redox Control of Hepatic Lipid Metabolism	5R01DK103750-05	23
2018	Redox control of hepatic lipid metabolism	5R01DK103750-04	23
2017	Redox control of hepatic lipid metabolism	5R01DK103750-03	23
2016	Redox control of hepatic lipid metabolism	5R01DK103750-02	23
2015	Redox control of hepatic lipid metabolism	1R01DK103750-01A1	23

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis Copy PMIDs To Clipboard

Watanabe Y, Watanabe K, Fujioka D, Nakamura K, Nakamura T, Uematsu M, Bachschmid MM, Matsui R, Kugiyama K. Protein S-glutathionylation stimulate adipogenesis by stabilizing C/EBPß in 3T3L1 cells. FASEB J. 2020 04; 34(4):5827-5837.View Related Profiles.

Bachschmid, Markus
Matsui, Reiko

PMID: 32141127; PMCID: PMC8491561; DOI: 10.1096/fj.201902575R;

Panagia M, He H, Baka T, Pimentel DR, Croteau D, Bachschmid MM, Balschi JA, Colucci WS, Luptak I. Increasing mitochondrial ATP synthesis with butyrate normalizes ADP and contractile function in metabolic heart disease. NMR Biomed. 2020 05; 33(5):e4258.View Related Profiles.

Pimentel, David
Luptak, Ivan
Panagia, Marcello
Bachschmid, Markus
Colucci, Wilson

PMID: 32066202; PMCID: PMC7165026; DOI: 10.1002/nbm.4258;

Matsui R, Ferran B, Oh A, Croteau D, Shao D, Han J, Pimentel DR, Bachschmid MM. Redox Regulation via Glutaredoxin-1 and Protein S-Glutathionylation. Antioxid Redox Signal. 2020 04 01; 32(10):677-700.View Related Profiles.

Oh, Albin
Pimentel, David
Shao, Di
Han, Jingyan
Bachschmid, Markus
Matsui, Reiko

PMID: 31813265; PMCID: PMC7047114; DOI: 10.1089/ars.2019.7963;

Yura Y, Chong BSH, Johnson RD, Watanabe Y, Tsukahara Y, Ferran B, Murdoch CE, Behring JB, McComb ME, Costello CE, Janssen-Heininger YMW, Cohen RA, Bachschmid MM, Matsui R. Endothelial cell-specific redox gene modulation inhibits angiogenesis but promotes B16F0 tumor growth in mice. FASEB J. 2019 12; 33(12):14147-14158.View Related Profiles.

Chong, Brian
Costello, Catherine
Murdoch, Colin
Behring, Jessica
McComb, Mark
Bachschmid, Markus
Matsui, Reiko
Cohen, Richard
Tsukahara, Yuko

PMID: 31647879; PMCID: PMC6894059; DOI: 10.1096/fj.201900786R;

Tian R, Colucci WS, Arany Z, Bachschmid MM, Ballinger SW, Boudina S, Bruce JE, Busija DW, Dikalov S, Dorn GW, Galis ZS, Gottlieb RA, Kelly DP, Kitsis RN, Kohr MJ, Levy D, Lewandowski ED, McClung JM, Mochly-Rosen D, O'Brien KD, O'Rourke B, Park JY, Ping P, Sack MN, Sheu SS, Shi Y, Shiva S, Wallace DC, Weiss RG, Vernon HJ, Wong R, Schwartz Longacre L. Unlocking the Secrets of Mitochondria in the Cardiovascular System: Path to a Cure in Heart Failure—A Report from the 2018 National Heart, Lung, and Blood Institute Workshop Circulation. 2019 10 01; 140(14):1205-1216.View Related Profiles.

Bachschmid, Markus
Colucci, Wilson

PMID: 31769940; PMCID: PMC6880654; DOI: 10.1161/CIRCULATIONAHA.119.040551;

Kimura T, Ferran B, Tsukahara Y, Shang Q, Desai S, Fedoce A, Pimentel DR, Luptak I, Adachi T, Ido Y, Matsui R, Bachschmid MM. Production of adeno-associated virus vectors for in vitro and in vivo applications. Sci Rep. 2019 09 19; 9(1):13601.View Related Profiles.

Pimentel, David
Luptak, Ivan
Bachschmid, Markus
Matsui, Reiko
Tsukahara, Yuko

PMID: 31537820; PMCID: PMC6753157; DOI: 10.1038/s41598-019-49624-w;

Luptak I, Morgan R, Baka T, Croteau D, Moverman D, Sarnak H, Kirber M, Bachschmid MM, Colucci WS, Pimentel DR. Genetically targeted fluorescent probes reveal dynamic calcium responses to adrenergic signaling in multiple cardiomyocyte compartments. Int J Biochem Cell Biol. 2019 09; 114:105569.View Related Profiles.

Pimentel, David
Luptak, Ivan
Bachschmid, Markus
Kirber, Michael
Morgan, Robert
Colucci, Wilson

PMID: 31299273; PMCID: PMC6832870; DOI: 10.1016/j.biocel.2019.105569;

Luptak I, Qin F, Sverdlov AL, Pimentel DR, Panagia M, Croteau D, Siwik DA, Bachschmid MM, He H, Balschi JA, Colucci WS. Energetic Dysfunction Is Mediated by Mitochondrial Reactive Oxygen Species and Precedes Structural Remodeling in Metabolic Heart Disease. Antioxid Redox Signal. 2019 09 01; 31(7):539-549.View Related Profiles.

Sverdlov, Aaron
Pimentel, David
Siwik, Deborah
Qin, Fuzhong
Luptak, Ivan
Panagia, Marcello
Bachschmid, Markus
Colucci, Wilson

PMID: 31088291; PMCID: PMC6648235; DOI: 10.1089/ars.2018.7707;

Shao D, Yao C, Kim MH, Fry J, Cohen RA, Costello CE, Matsui R, Seta F, McComb ME, Bachschmid MM. Improved mass spectrometry-based activity assay reveals oxidative and metabolic stress as sirtuin-1 regulators. Redox Biol. 2019 04; 22:101150.View Related Profiles.

Costello, Catherine
Yao, Chunxiang
Shao, Di
Seta, Francesca
Fry, Jessica
McComb, Mark
Bachschmid, Markus
Matsui, Reiko
Cohen, Richard

PMID: 30877853; PMCID: PMC6423473; DOI: 10.1016/j.redox.2019.101150;

Taylor E, Huang N, Bodde J, Ellison A, Killiany R, Bachschmid MM, Hamilton J. MRI of atherosclerosis and fatty liver disease in cholesterol fed rabbits. J Transl Med. 2018 08 01; 16(1):215.View Related Profiles.

Taylor, Erik
Hamilton, James
Bachschmid, Markus
Huang, Nasi
Killiany, Ronald

PMID: 30068362; PMCID: PMC6071403; DOI: 10.1186/s12967-018-1587-3;

Showing 10 of 92 results. Show More

Anathy V, Lahue KG, Chapman DG, Chia SB, Casey DT, Aboushousha R, van der Velden JLJ, Elko E, Hoffman SM, McMillan DH, Jones JT, Nolin JD, Abdalla S, Schneider R, Seward DJ, Roberson EC, Liptak MD, Cousins ME, Butnor KJ, Taatjes DJ, Budd RC, Irvin CG, Ho YS, Hakem R, Brown KK, Matsui R, Bachschmid MM, Gomez JL, Kaminski N, van der Vliet A, Janssen-Heininger YMW. Reducing protein oxidation reverses lung fibrosis. Nat Med. 2018 08; 24(8):1128-1135.View Related Profiles.

Bachschmid, Markus
Matsui, Reiko

PMID: 29988126; PMCID: PMC6204256; DOI: 10.1038/s41591-018-0090-y;

Luptak I, Sverdlov AL, Panagia M, Qin F, Pimentel DR, Croteau D, Siwik DA, Ingwall JS, Bachschmid MM, Balschi JA, Colucci WS. Decreased ATP production and myocardial contractile reserve in metabolic heart disease. J Mol Cell Cardiol. 2018 03; 116:106-114.View Related Profiles.

Sverdlov, Aaron
Pimentel, David
Siwik, Deborah
Qin, Fuzhong
Luptak, Ivan
Panagia, Marcello
Bachschmid, Markus
Colucci, Wilson

PMID: 29409987; PMCID: PMC5871926; DOI: 10.1016/j.yjmcc.2018.01.017;

Yoon S, Beermann ML, Yu B, Shao D, Bachschmid M, Miller JB. Aberrant Caspase Activation in Laminin-a2-Deficient Human Myogenic Cells is Mediated by p53 and Sirtuin Activity. J Neuromuscul Dis. 2018; 5(1):59-73.View Related Profiles.

Shao, Di
Miller, Jeffrey
Bachschmid, Markus

PMID: 29278895; PMCID: PMC5836413; DOI: 10.3233/JND-170262;

Egea J, Fabregat I, Frapart YM, Ghezzi P, Görlach A, Kietzmann T, Kubaichuk K, Knaus UG, Lopez MG, Olaso-Gonzalez G, Petry A, Schulz R, Vina J, Winyard P, Abbas K, Ademowo OS, Afonso CB, Andreadou I, Antelmann H, Antunes F, Aslan M, Bachschmid MM, Barbosa RM, Belousov V, Berndt C, Bernlohr D, Bertrán E, Bindoli A, Bottari SP, Brito PM, Carrara G, Casas AI, Chatzi A, Chondrogianni N, Conrad M, Cooke MS, Costa JG, Cuadrado A, My-Chan Dang P, De Smet B, Debelec-Butuner B, Dias IHK, Dunn JD, Edson AJ, El Assar M, El-Benna J, Ferdinandy P, Fernandes AS, Fladmark KE, Förstermann U, Giniatullin R, Giricz Z, Görbe A, Griffiths H, Hampl V, Hanf A, Herget J, Hernansanz-Agustín P, Hillion M, Huang J, Ilikay S, Jansen-Dürr P, Jaquet V, Joles JA, Kalyanaraman B, Kaminskyy D, Karbaschi M, Kleanthous M, Klotz LO, Korac B, Korkmaz KS, Koziel R, Kracun D, Krause KH, Kren V, Krieg T, Laranjinha J, Lazou A, Li H, Martínez-Ruiz A, Matsui R, McBean GJ, Meredith SP, Messens J, Miguel V, Mikhed Y, Milisav I, Milkovic L, Miranda-Vizuete A, Mojovic M, Monsalve M, Mouthuy PA, Mulvey J, Münzel T, Muzykantov V, Nguyen ITN, Oelze M, Oliveira NG, Palmeira CM, Papaevgeniou N, Pavicevic A, Pedre B, Peyrot F, Phylactides M, Pircalabioru GG, Pitt AR, Poulsen HE, Prieto I, Rigobello MP, Robledinos-Antón N, Rodríguez-Mañas L, Rolo AP, Rousset F, Ruskovska T, Saraiva N, Sasson S, Schröder K, Semen K, Seredenina T, Shakirzyanova A, Smith GL, Soldati T, Sousa BC, Spickett CM, Stancic A, Stasia MJ, Steinbrenner H, Stepanic V, Steven S, Tokatlidis K, Tuncay E, Turan B, Ursini F, Vacek J, Vajnerova O, Valentová K, Van Breusegem F, Varisli L, Veal EA, Yalçin AS, Yelisyeyeva O, Žarkovic N, Zatloukalová M, Zielonka J, Touyz RM, Papapetropoulos A, Grune T, Lamas S, Schmidt HHHW, Di Lisa F, Daiber A. Corrigendum to "European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)" [Redox Biol. 13 (2017) 94-162]. Redox Biol. 2018 04; 14:694-696. PMID: 29107648

Egea J, Fabregat I, Frapart YM, Ghezzi P, Görlach A, Kietzmann T, Kubaichuk K, Knaus UG, Lopez MG, Olaso-Gonzalez G, Petry A, Schulz R, Vina J, Winyard P, Abbas K, Ademowo OS, Afonso CB, Andreadou I, Antelmann H, Antunes F, Aslan M, Bachschmid MM, Barbosa RM, Belousov V, Berndt C, Bernlohr D, Bertrán E, Bindoli A, Bottari SP, Brito PM, Carrara G, Casas AI, Chatzi A, Chondrogianni N, Conrad M, Cooke MS, Costa JG, Cuadrado A, My-Chan Dang P, De Smet B, Debelec-Butuner B, Dias IHK, Dunn JD, Edson AJ, El Assar M, El-Benna J, Ferdinandy P, Fernandes AS, Fladmark KE, Förstermann U, Giniatullin R, Giricz Z, Görbe A, Griffiths H, Hampl V, Hanf A, Herget J, Hernansanz-Agustín P, Hillion M, Huang J, Ilikay S, Jansen-Dürr P, Jaquet V, Joles JA, Kalyanaraman B, Kaminskyy D, Karbaschi M, Kleanthous M, Klotz LO, Korac B, Korkmaz KS, Koziel R, Kracun D, Krause KH, Kren V, Krieg T, Laranjinha J, Lazou A, Li H, Martínez-Ruiz A, Matsui R, McBean GJ, Meredith SP, Messens J, Miguel V, Mikhed Y, Milisav I, Milkovic L, Miranda-Vizuete A, Mojovic M, Monsalve M, Mouthuy PA, Mulvey J, Münzel T, Muzykantov V, Nguyen ITN, Oelze M, Oliveira NG, Palmeira CM, Papaevgeniou N, Pavicevic A, Pedre B, Peyrot F, Phylactides M, Pircalabioru GG, Pitt AR, Poulsen HE, Prieto I, Rigobello MP, Robledinos-Antón N, Rodríguez-Mañas L, Rolo AP, Rousset F, Ruskovska T, Saraiva N, Sasson S, Schröder K, Semen K, Seredenina T, Shakirzyanova A, Smith GL, Soldati T, Sousa BC, Spickett CM, Stancic A, Stasia MJ, Steinbrenner H, Stepanic V, Steven S, Tokatlidis K, Tuncay E, Turan B, Ursini F, Vacek J, Vajnerova O, Valentová K, Van Breusegem F, Varisli L, Veal EA, Yalçin AS, Yelisyeyeva O, Žarkovic N, Zatloukalová M, Zielonka J, Touyz RM, Papapetropoulos A, Grune T, Lamas S, Schmidt HHHW, Di Lisa F, Daiber A. European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS). Redox Biol. 2017 10; 13:94-162.View Related Profiles.

Bachschmid, Markus
Matsui, Reiko

PMID: 28577489; PMCID: PMC5458069; DOI: 10.1016/j.redox.2017.05.007;

Shao D, Han J, Hou X, Fry J, Behring JB, Seta F, Long MT, Roy HK, Cohen RA, Matsui R, Bachschmid MM. Glutaredoxin-1 Deficiency Causes Fatty Liver and Dyslipidemia by Inhibiting Sirtuin-1. Antioxid Redox Signal. 2017 Aug 20; 27(6):313-327.View Related Profiles.

Shao, Di
Seta, Francesca
Roy, Hemant
Behring, Jessica
Fry, Jessica
Han, Jingyan
Bachschmid, Markus
Long, Michelle
Matsui, Reiko
Cohen, Richard

PMID: 27958883; PMCID: PMC5563925; DOI: 10.1089/ars.2016.6716;

Vikram A, Lewarchik CM, Yoon JY, Naqvi A, Kumar S, Morgan GM, Jacobs JS, Li Q, Kim YR, Kassan M, Liu J, Gabani M, Kumar A, Mehdi H, Zhu X, Guan X, Kutschke W, Zhang X, Boudreau RL, Dai S, Matasic DS, Jung SB, Margulies KB, Kumar V, Bachschmid MM, London B, Irani K. Sirtuin 1 regulates cardiac electrical activity by deacetylating the cardiac sodium channel. Nat Med. 2017 Mar; 23(3):361-367. PMID: 28191886; DOI: 10.1038/nm.4284;

Kumar S, Kim YR, Vikram A, Naqvi A, Li Q, Kassan M, Kumar V, Bachschmid MM, Jacobs JS, Kumar A, Irani K. Sirtuin1-regulated lysine acetylation of p66Shc governs diabetes-induced vascular oxidative stress and endothelial dysfunction. Proc Natl Acad Sci U S A. 2017 02 14; 114(7):1714-1719. PMID: 28137876; DOI: 10.1073/pnas.1614112114;

Han J, Weisbrod RM, Shao D, Watanabe Y, Yin X, Bachschmid MM, Seta F, Janssen-Heininger YMW, Matsui R, Zang M, Hamburg NM, Cohen RA. The redox mechanism for vascular barrier dysfunction associated with metabolic disorders: Glutathionylation of Rac1 in endothelial cells. Redox Biol. 2016 Oct; 9:306-319.View Related Profiles.

Shao, Di
Seta, Francesca
Han, Jingyan
Bachschmid, Markus
Hamburg, Naomi
Matsui, Reiko
Cohen, Richard

PMID: 27693992; PMCID: PMC5045950; DOI: 10.1016/j.redox.2016.09.003;

Fry JL, Al Sayah L, Weisbrod RM, Van Roy I, Weng X, Cohen RA, Bachschmid MM, Seta F. Vascular Smooth Muscle Sirtuin-1 Protects Against Diet-Induced Aortic Stiffness. Hypertension. 2016 Sep; 68(3):775-84.View Related Profiles.

Seta, Francesca
Fry, Jessica
Bachschmid, Markus
Cohen, Richard

PMID: 27432859; PMCID: PMC4982825; DOI: 10.1161/HYPERTENSIONAHA.116.07622;

Gorelenkova Miller O, Behring JB, Siedlak SL, Jiang S, Matsui R, Bachschmid MM, Zhu X, Mieyal JJ. Upregulation of Glutaredoxin-1 Activates Microglia and Promotes Neurodegeneration: Implications for Parkinson's Disease. Antioxid Redox Signal. 2016 Dec 20; 25(18):967-982.View Related Profiles.

Behring, Jessica
Bachschmid, Markus
Matsui, Reiko

PMID: 27224303; PMCID: PMC5175443; DOI: 10.1089/ars.2015.6598;

Cohen RA, Murdoch CE, Watanabe Y, Bolotina VM, Evangelista AM, Haeussler DJ, Smith MD, Mei Y, Tong X, Han J, Behring JB, Bachschmid MM, Matsui R. Endothelial Cell Redox Regulation of Ischemic Angiogenesis. J Cardiovasc Pharmacol. 2016 Jun; 67(6):458-64.View Related Profiles.

Murdoch, Colin
Haeussler, Dagmar
Behring, Jessica
Han, Jingyan
Bachschmid, Markus
Matsui, Reiko
Cohen, Richard
Bolotina, Victoria
Tong, XiaoYong

PMID: 26927696; PMCID: PMC4899292; DOI: 10.1097/FJC.0000000000000381;

Watanabe Y, Murdoch CE, Sano S, Ido Y, Bachschmid MM, Cohen RA, Matsui R. Glutathione adducts induced by ischemia and deletion of glutaredoxin-1 stabilize HIF-1a and improve limb revascularization. Proc Natl Acad Sci U S A. 2016 May 24; 113(21):6011-6.View Related Profiles.

Murdoch, Colin
Bachschmid, Markus
Matsui, Reiko
Cohen, Richard
Ido, Yasuo

PMID: 27162359; PMCID: PMC4889374; DOI: 10.1073/pnas.1524198113;

Sverdlov AL, Elezaby A, Qin F, Behring JB, Luptak I, Calamaras TD, Siwik DA, Miller EJ, Liesa M, Shirihai OS, Pimentel DR, Cohen RA, Bachschmid MM, Colucci WS. Mitochondrial Reactive Oxygen Species Mediate Cardiac Structural, Functional, and Mitochondrial Consequences of Diet-Induced Metabolic Heart Disease. J Am Heart Assoc. 2016 Jan 11; 5(1).View Related Profiles.

Sverdlov, Aaron
Elezaby, Aly
Pimentel, David
Siwik, Deborah
Qin, Fuzhong
Luptak, Ivan
Behring, Jessica
Bachschmid, Markus
Shirihai, Orian
Cohen, Richard
Colucci, Wilson

PMID: 26755553; PMCID: PMC4859372; DOI: 10.1161/JAHA.115.002555;

Ji Y, Bachschmid MM, Costello CE, Lin C. S- to N-Palmitoyl Transfer During Proteomic Sample Preparation. J Am Soc Mass Spectrom. 2016 Apr; 27(4):677-85.View Related Profiles.

Costello, Catherine
Lin, Cheng
Bachschmid, Markus
Ji, Yuhuan

PMID: 26729453; PMCID: PMC4794353; DOI: 10.1007/s13361-015-1319-3;

Miller EJ, Calamaras T, Elezaby A, Sverdlov A, Qin F, Luptak I, Wang K, Sun X, Vijay A, Croteau D, Bachschmid M, Cohen RA, Walsh K, Colucci WS. Partial Liver Kinase B1 (LKB1) Deficiency Promotes Diastolic Dysfunction, De Novo Systolic Dysfunction, Apoptosis, and Mitochondrial Dysfunction With Dietary Metabolic Challenge. J Am Heart Assoc. 2015 Dec 31; 5(1).View Related Profiles.

Sverdlov, Aaron
Elezaby, Aly
Qin, Fuzhong
Luptak, Ivan
Walsh, Kenneth
Bachschmid, Markus
Cohen, Richard
Colucci, Wilson

PMID: 26722122; PMCID: PMC4859355; DOI: 10.1161/JAHA.115.002277;

Yao C, Behring JB, Shao D, Sverdlov AL, Whelan SA, Elezaby A, Yin X, Siwik DA, Seta F, Costello CE, Cohen RA, Matsui R, Colucci WS, McComb ME, Bachschmid MM. Overexpression of Catalase Diminishes Oxidative Cysteine Modifications of Cardiac Proteins. PLoS One. 2015; 10(12):e0144025.View Related Profiles.

Sverdlov, Aaron
Elezaby, Aly
Costello, Catherine
Yao, Chunxiang
Siwik, Deborah
Shao, Di
Seta, Francesca
Behring, Jessica
McComb, Mark
Bachschmid, Markus
Matsui, Reiko
Cohen, Richard
Whelan, Stephen
Colucci, Wilson
Yin, Xiaoyan

PMID: 26642319; PMCID: PMC4671598; DOI: 10.1371/journal.pone.0144025;

Peskin AV, Pace PE, Behring JB, Paton LN, Soethoudt M, Bachschmid MM, Winterbourn CC. Glutathionylation of the Active Site Cysteines of Peroxiredoxin 2 and Recycling by Glutaredoxin. J Biol Chem. 2016 Feb 5; 291(6):3053-62.View Related Profiles.

Behring, Jessica
Bachschmid, Markus

PMID: 26601956; PMCID: PMC4742766; DOI: 10.1074/jbc.M115.692798;

Fry JL, Shiraishi Y, Turcotte R, Yu X, Gao YZ, Akiki R, Bachschmid M, Zhang Y, Morgan KG, Cohen RA, Seta F. Vascular Smooth Muscle Sirtuin-1 Protects Against Aortic Dissection During Angiotensin II-Induced Hypertension. J Am Heart Assoc. 2015 Sep; 4(9):e002384.View Related Profiles.

Seta, Francesca
Fry, Jessica
Morgan, Kathleen
Bachschmid, Markus
Cohen, Richard

PMID: 26376991; PMCID: PMC4599512; DOI: 10.1161/JAHA.115.002384;

Ji Y, Liu M, Bachschmid MM, Costello CE, Lin C. Surfactant-Induced Artifacts during Proteomic Sample Preparation. Anal Chem. 2015 Jun 2; 87(11):5500-4.View Related Profiles.

Costello, Catherine
Lin, Cheng
Bachschmid, Markus

PMID: 25945600; PMCID: PMC4574305; DOI: 10.1021/acs.analchem.5b00249;

Murdoch CE, Bachschmid MM, Matsui R. Regulation of neovascularization by S-glutathionylation via the Wnt5a/sFlt-1 pathway. Biochem Soc Trans. 2014 Dec; 42(6):1665-70.View Related Profiles.

Murdoch, Colin
Bachschmid, Markus
Matsui, Reiko

PMID: 25399587; PMCID: PMC4934611; DOI: 10.1042/BST20140213;

Sverdlov AL, Elezaby A, Behring JB, Bachschmid MM, Luptak I, Tu VH, Siwik DA, Miller EJ, Liesa M, Shirihai OS, Pimentel DR, Cohen RA, Colucci WS. High fat, high sucrose diet causes cardiac mitochondrial dysfunction due in part to oxidative post-translational modification of mitochondrial complex II. J Mol Cell Cardiol. 2015 Jan; 78:165-73.View Related Profiles.

Sverdlov, Aaron
Elezaby, Aly
Pimentel, David
Siwik, Deborah
Miller, Edward
Luptak, Ivan
Behring, Jessica
Liesa Roig, Marc
Bachschmid, Markus
Shirihai, Orian
Cohen, Richard
Tu, Vivian
Colucci, Wilson

PMID: 25109264; PMCID: PMC4268348; DOI: 10.1016/j.yjmcc.2014.07.018;

Murdoch CE, Shuler M, Haeussler DJ, Kikuchi R, Bearelly P, Han J, Watanabe Y, Fuster JJ, Walsh K, Ho YS, Bachschmid MM, Cohen RA, Matsui R. Glutaredoxin-1 up-regulation induces soluble vascular endothelial growth factor receptor 1, attenuating post-ischemia limb revascularization. J Biol Chem. 2014 Mar 21; 289(12):8633-44.View Related Profiles.

Murdoch, Colin
Haeussler, Dagmar
Han, Jingyan
Fuster Ortuno, Jose
Walsh, Kenneth
Bachschmid, Markus
Matsui, Reiko
Cohen, Richard
Kikuchi, Ryosuke

PMID: 24482236; PMCID: PMC3961686; DOI: 10.1074/jbc.M113.517219;

Behring JB, Kumar V, Whelan SA, Chauhan P, Siwik DA, Costello CE, Colucci WS, Cohen RA, McComb ME, Bachschmid MM. Does reversible cysteine oxidation link the Western diet to cardiac dysfunction? FASEB J. 2014 May; 28(5):1975-87.View Related Profiles.

Costello, Catherine
Siwik, Deborah
Behring, Jessica
McComb, Mark
Bachschmid, Markus
Cohen, Richard
Whelan, Stephen
Kumar, Vikas
Colucci, Wilson

PMID: 24469991; PMCID: PMC4046179; DOI: 10.1096/fj.13-233445;

Shao D, Fry JL, Han J, Hou X, Pimentel DR, Matsui R, Cohen RA, Bachschmid MM. A redox-resistant sirtuin-1 mutant protects against hepatic metabolic and oxidant stress. J Biol Chem. 2014 Mar 14; 289(11):7293-306.View Related Profiles.

Pimentel, David
Shao, Di
Fry, Jessica
Han, Jingyan
Bachschmid, Markus
Matsui, Reiko
Cohen, Richard

PMID: 24451382; PMCID: PMC3953247; DOI: 10.1074/jbc.M113.520403;

Ji Y, Leymarie N, Haeussler DJ, Bachschmid MM, Costello CE, Lin C. Direct detection of S-palmitoylation by mass spectrometry. Anal Chem. 2013 Dec 17; 85(24):11952-9.View Related Profiles.

Costello, Catherine
Lin, Cheng
Haeussler, Dagmar
Bachschmid, Markus
Leymarie, Nancy
Ji, Yuhuan

PMID: 24279456; PMCID: PMC3912867; DOI: 10.1021/ac402850s;

Oelze M, Kröller-Schön S, Steven S, Lubos E, Doppler C, Hausding M, Tobias S, Brochhausen C, Li H, Torzewski M, Wenzel P, Bachschmid M, Lackner KJ, Schulz E, Münzel T, Daiber A. Glutathione peroxidase-1 deficiency potentiates dysregulatory modifications of endothelial nitric oxide synthase and vascular dysfunction in aging. Hypertension. 2014 Feb; 63(2):390-6. PMID: 24296279; DOI: 10.1161/HYPERTENSIONAHA.113.01602;

Daiber A, Daub S, Bachschmid M, Schildknecht S, Oelze M, Steven S, Schmidt P, Megner A, Wada M, Tanabe T, Münzel T, Bottari S, Ullrich V. Protein tyrosine nitration and thiol oxidation by peroxynitrite-strategies to prevent these oxidative modifications. Int J Mol Sci. 2013; 14(4):7542-70. PMID: 23567270; PMCID: PMC3645702; DOI: 10.3390/ijms14047542;

Haeussler DJ, Pimentel DR, Hou X, Burgoyne JR, Cohen RA, Bachschmid MM. Endomembrane H-Ras controls vascular endothelial growth factor-induced nitric-oxide synthase-mediated endothelial cell migration. J Biol Chem. 2013 May 24; 288(21):15380-9.View Related Profiles.

Haeussler, Dagmar
Pimentel, David
Burgoyne, Joseph
Bachschmid, Markus
Cohen, Richard

PMID: 23548900; PMCID: PMC3663556; DOI: 10.1074/jbc.M112.427765;

Kumar V, Calamaras TD, Haeussler D, Colucci WS, Cohen RA, McComb ME, Pimentel D, Bachschmid MM. Cardiovascular redox and ox stress proteomics. Antioxid Redox Signal. 2012 Dec 1; 17(11):1528-59.View Related Profiles.

Haeussler, Dagmar
Pimentel, David
McComb, Mark
Bachschmid, Markus
Cohen, Richard
Kumar, Vikas
Colucci, Wilson

PMID: 22607061; PMCID: PMC3448941; DOI: 10.1089/ars.2012.4706;

Schildknecht S, Karreman C, Daiber A, Zhao C, Hamacher J, Perlman D, Jung B, van der Loo B, O'Connor P, Leist M, Ullrich V, Bachschmid MM. Autocatalytic nitration of prostaglandin endoperoxide synthase-2 by nitrite inhibits prostanoid formation in rat alveolar macrophages. Antioxid Redox Signal. 2012 Nov 15; 17(10):1393-406. PMID: 22578329; PMCID: PMC3437048; DOI: 10.1089/ars.2011.4485;

Pimentel D, Haeussler DJ, Matsui R, Burgoyne JR, Cohen RA, Bachschmid MM. Regulation of cell physiology and pathology by protein S-glutathionylation: lessons learned from the cardiovascular system. Antioxid Redox Signal. 2012 Mar 15; 16(6):524-42.View Related Profiles.

Haeussler, Dagmar
Pimentel, David
Burgoyne, Joseph
Bachschmid, Markus
Matsui, Reiko
Cohen, Richard

PMID: 22010840; PMCID: PMC3270052; DOI: 10.1089/ars.2011.4336;

Bachschmid MM, Schildknecht S, Matsui R, Zee R, Haeussler D, Cohen RA, Pimental D, Loo Bv. Vascular aging: chronic oxidative stress and impairment of redox signaling-consequences for vascular homeostasis and disease. Ann Med. 2013 Feb; 45(1):17-36.View Related Profiles.

Haeussler, Dagmar
Bachschmid, Markus
Matsui, Reiko
Cohen, Richard

PMID: 22380696; PMCID: PMC3717565; DOI: 10.3109/07853890.2011.645498;

Burgoyne JR, Haeussler DJ, Kumar V, Ji Y, Pimental DR, Zee RS, Costello CE, Lin C, McComb ME, Cohen RA, Bachschmid MM. Oxidation of HRas cysteine thiols by metabolic stress prevents palmitoylation in vivo and contributes to endothelial cell apoptosis. FASEB J. 2012 Feb; 26(2):832-41.View Related Profiles.

Costello, Catherine
Lin, Cheng
Haeussler, Dagmar
Burgoyne, Joseph
McComb, Mark
Bachschmid, Markus
Cohen, Richard
Kumar, Vikas

PMID: 22085642; PMCID: PMC3290434; DOI: 10.1096/fj.11-189415;

Xu S, Jiang B, Hou X, Shi C, Bachschmid MM, Zang M, Verbeuren TJ, Cohen RA. High-fat diet increases and the polyphenol, S17834, decreases acetylation of the sirtuin-1-dependent lysine-382 on p53 and apoptotic signaling in atherosclerotic lesion-prone aortic endothelium of normal mice. J Cardiovasc Pharmacol. 2011 Sep; 58(3):263-71.View Related Profiles.

Bachschmid, Markus
Zang, Mengwei
Cohen, Richard

PMID: 21654327; PMCID: PMC3168693; DOI: 10.1097/FJC.0b013e3182239eb7;

Haeussler DJ, Evangelista AM, Burgoyne JR, Cohen RA, Bachschmid MM, Pimental DR. Checkpoints in adenoviral production: cross-contamination and E1A. PLoS One. 2011; 6(8):e23160.View Related Profiles.

Haeussler, Dagmar
Pimentel, David
Burgoyne, Joseph
Bachschmid, Markus
Cohen, Richard

PMID: 21826235; PMCID: PMC3149638; DOI: 10.1371/journal.pone.0023160;

Lugus JJ, Ngoh GA, Bachschmid MM, Walsh K. Mitofusins are required for angiogenic function and modulate different signaling pathways in cultured endothelial cells. J Mol Cell Cardiol. 2011 Dec; 51(6):885-93.View Related Profiles.

Ngoh, Gladys
Lugus, Jesse
Bachschmid, Markus

PMID: 21839087; PMCID: PMC3208756; DOI: 10.1016/j.yjmcc.2011.07.023;

Zee RS, Yoo CB, Pimentel DR, Perlman DH, Burgoyne JR, Hou X, McComb ME, Costello CE, Cohen RA, Bachschmid MM. Redox regulation of sirtuin-1 by S-glutathiolation. Antioxid Redox Signal. 2010 Oct 1; 13(7):1023-32.View Related Profiles.

Costello, Catherine
Pimentel, David
Burgoyne, Joseph
McComb, Mark
Bachschmid, Markus
Cohen, Richard

PMID: 20392170; PMCID: PMC2959181; DOI: 10.1089/ars.2010.3251;

Bachschmid MM, Xu S, Maitland-Toolan KA, Ho YS, Cohen RA, Matsui R. Attenuated cardiovascular hypertrophy and oxidant generation in response to angiotensin II infusion in glutaredoxin-1 knockout mice. Free Radic Biol Med. 2010 Oct 15; 49(7):1221-9.View Related Profiles.

Bachschmid, Markus
Matsui, Reiko
Cohen, Richard

PMID: 20638471; PMCID: PMC2930025; DOI: 10.1016/j.freeradbiomed.2010.07.005;

Daiber A, Schildknecht S, Müller J, Kamuf J, Bachschmid MM, Ullrich V. Chemical model systems for cellular nitros(yl)ation reactions. Free Radic Biol Med. 2009 Aug 15; 47(4):458-67. PMID: 19477267; DOI: 10.1016/j.freeradbiomed.2009.05.019;

Kienhöfer J, Häussler DJ, Ruckelshausen F, Muessig E, Weber K, Pimentel D, Ullrich V, Bürkle A, Bachschmid MM. Association of mitochondrial antioxidant enzymes with mitochondrial DNA as integral nucleoid constituents. FASEB J. 2009 Jul; 23(7):2034-44.View Related Profiles.

Pimentel, David
Bachschmid, Markus

PMID: 19228881; PMCID: PMC2704585; DOI: 10.1096/fj.08-113571;

van der Loo B, Schildknecht S, Zee R, Bachschmid MM. Signalling processes in endothelial ageing in relation to chronic oxidative stress and their potential therapeutic implications in humans. Exp Physiol. 2009 Mar; 94(3):305-10. PMID: 18996949; DOI: 10.1113/expphysiol.2008.043315;

Osto E, Matter CM, Kouroedov A, Malinski T, Bachschmid M, Camici GG, Kilic U, Stallmach T, Boren J, Iliceto S, Lüscher TF, Cosentino F. c-Jun N-terminal kinase 2 deficiency protects against hypercholesterolemia-induced endothelial dysfunction and oxidative stress. Circulation. 2008 Nov 11; 118(20):2073-80. PMID: 18955669; DOI: 10.1161/CIRCULATIONAHA.108.765032;

Chitalia VC, Foy RL, Bachschmid MM, Zeng L, Panchenko MV, Zhou MI, Bharti A, Seldin DC, Lecker SH, Dominguez I, Cohen HT. Jade-1 inhibits Wnt signalling by ubiquitylating beta-catenin and mediates Wnt pathway inhibition by pVHL. Nat Cell Biol. 2008 Oct; 10(10):1208-16.View Related Profiles.

Bharti, Ajit
Seldin, David
Cohen, Herbert
Dominguez, Maria
Panchenko, Maria
Bachschmid, Markus
Zhou, Mina
Chitalia, Vipul

PMID: 18806787; PMCID: PMC2830866; DOI: 10.1038/ncb1781;

Wenzel P, Schuhmacher S, Kienhöfer J, Müller J, Hortmann M, Oelze M, Schulz E, Treiber N, Kawamoto T, Scharffetter-Kochanek K, Münzel T, Bürkle A, Bachschmid MM, Daiber A. Manganese superoxide dismutase and aldehyde dehydrogenase deficiency increase mitochondrial oxidative stress and aggravate age-dependent vascular dysfunction. Cardiovasc Res. 2008 Nov 1; 80(2):280-9. PMID: 18596060; DOI: 10.1093/cvr/cvn182;

Schildknecht S, van der Loo B, Weber K, Tiefenthaler K, Daiber A, Bachschmid MM. Endogenous peroxynitrite modulates PGHS-1-dependent thromboxane A2 formation and aggregation in human platelets. Free Radic Biol Med. 2008 Aug 15; 45(4):512-20. PMID: 18514074; DOI: 10.1016/j.freeradbiomed.2008.04.042;

Schildknecht S, Daiber A, Ghisla S, Cohen RA, Bachschmid MM. Acetaminophen inhibits prostanoid synthesis by scavenging the PGHS-activator peroxynitrite. FASEB J. 2008 Jan; 22(1):215-24.View Related Profiles.

Bachschmid, Markus
Cohen, Richard

PMID: 17724253

Tanner FC, van der Loo B, Shaw S, Greutert H, Bachschmid MM, Berrozpe M, Rozenberg I, Blau N, Siebenmann R, Schmidli J, Meyer P, Lüscher TF. Inactivity of nitric oxide synthase gene in the atherosclerotic human carotid artery. Basic Res Cardiol. 2007 Jul; 102(4):308-17. PMID: 17356797

Camici GG, Schiavoni M, Francia P, Bachschmid M, Martin-Padura I, Hersberger M, Tanner FC, Pelicci P, Volpe M, Anversa P, Lüscher TF, Cosentino F. Genetic deletion of p66(Shc) adaptor protein prevents hyperglycemia-induced endothelial dysfunction and oxidative stress. Proc Natl Acad Sci U S A. 2007 Mar 20; 104(12):5217-22. PMID: 17360381; PMCID: PMC1829289

Griffoni C, Spisni E, Strillacci A, Toni M, Bachschmid MM, Tomasi V. Selective inhibition of prostacyclin synthase activity by rofecoxib. J Cell Mol Med. 2007 Mar-Apr; 11(2):327-38. PMID: 17488481

Wenzel P, Hink U, Oelze M, Schuppan S, Schaeuble K, Schildknecht S, Ho KK, Weiner H, Bachschmid M, Münzel T, Daiber A. Role of reduced lipoic acid in the redox regulation of mitochondrial aldehyde dehydrogenase (ALDH-2) activity. Implications for mitochondrial oxidative stress and nitrate tolerance. J Biol Chem. 2007 Jan 5; 282(1):792-9. PMID: 17102135

Clavreul N, Bachschmid MM, Hou X, Shi C, Idrizovic A, Ido Y, Pimentel D, Cohen RA. S-glutathiolation of p21ras by peroxynitrite mediates endothelial insulin resistance caused by oxidized low-density lipoprotein. Arterioscler Thromb Vasc Biol. 2006 Nov; 26(11):2454-61.View Related Profiles.

Pimentel, David
Bachschmid, Markus
Cohen, Richard
Ido, Yasuo

PMID: 16931794

van der Loo B, Bachschmid M, Skepper JN, Labugger R, Schildknecht S, Hahn R, Müssig E, Gygi D, Lüscher TF. Age-associated cellular relocation of Sod 1 as a self-defense is a futile mechanism to prevent vascular aging. Biochem Biophys Res Commun. 2006 Jun 9; 344(3):972-80. PMID: 16631605

Schildknecht S, Heinz K, Daiber A, Hamacher J, Kavaklí C, Ullrich V, Bachschmid M. Autocatalytic tyrosine nitration of prostaglandin endoperoxide synthase-2 in LPS-stimulated RAW 264.7 macrophages. Biochem Biophys Res Commun. 2006 Feb 3; 340(1):318-25. PMID: 16375865

Aleksandrov DA, Zagryagskaya AN, Pushkareva MA, Bachschmid M, Peters-Golden M, Werz O, Steinhilber D, Sud'ina GF. Cholesterol and its anionic derivatives inhibit 5-lipoxygenase activation in polymorphonuclear leukocytes and MonoMac6 cells. FEBS J. 2006 Feb; 273(3):548-57. PMID: 16420478

Daiber A, Oelze M, Coldewey M, Kaiser K, Huth C, Schildknecht S, Bachschmid M, Nazirisadeh Y, Ullrich V, Mülsch A, Münzel T, Tsilimingas N. Hydralazine is a powerful inhibitor of peroxynitrite formation as a possible explanation for its beneficial effects on prognosis in patients with congestive heart failure. Biochem Biophys Res Commun. 2005 Dec 30; 338(4):1865-74. PMID: 16289107

Frein D, Schildknecht S, Bachschmid M, Ullrich V. Redox regulation: a new challenge for pharmacology. Biochem Pharmacol. 2005 Sep 15; 70(6):811-23. PMID: 15899473

Bachschmid M, Schildknecht S, Ullrich V. Redox regulation of vascular prostanoid synthesis by the nitric oxide-superoxide system. Biochem Biophys Res Commun. 2005 Dec 9; 338(1):536-42. PMID: 16153593

Schildknecht S, Bachschmid M, Ullrich V. Peroxynitrite provides the peroxide tone for PGHS-2-dependent prostacyclin synthesis in vascular smooth muscle cells. FASEB J. 2005 Jul; 19(9):1169-71. PMID: 15878931

Bachschmid MM, van der Loo B. A new "sunshine" in the vasculature? Circulation. 2005 Apr 5; 111(13):1571-3. PMID: 15811866

Schildknecht S, Bachschmid M, Weber K, Maass D, Ullrich V. Endotoxin elicits nitric oxide release in rat but prostacyclin synthesis in human and bovine vascular smooth muscle cells. Biochem Biophys Res Commun. 2005 Feb 4; 327(1):43-8. PMID: 15629427

Klumpp G, Schildknecht S, Nastainczyk W, Ullrich V, Bachschmid M. Prostacyclin in the cardiovascular system: new aspects and open questions. Pharmacol Rep. 2005; 57 Suppl:120-6. PMID: 16415492

van der Loo B, Bachschmid M, Labugger R, Schildknecht S, Kilo J, Hahn R, Palacios-Callender M, Lüscher TF. Expression and activity patterns of nitric oxide synthases and antioxidant enzymes reveal a substantial heterogeneity between cardiac and vascular aging in the rat. Biogerontology. 2005; 6(5):325-34. PMID: 16463109

Francia P, delli Gatti C, Bachschmid M, Martin-Padura I, Savoia C, Migliaccio E, Pelicci PG, Schiavoni M, Lüscher TF, Volpe M, Cosentino F. Deletion of p66shc gene protects against age-related endothelial dysfunction. Circulation. 2004 Nov 2; 110(18):2889-95. PMID: 15505103

Daiber A, Oelze M, Coldewey M, Bachschmid M, Wenzel P, Sydow K, Wendt M, Kleschyov AL, Stalleicken D, Ullrich V, Mülsch A, Münzel T. Oxidative stress and mitochondrial aldehyde dehydrogenase activity: a comparison of pentaerythritol tetranitrate with other organic nitrates. Mol Pharmacol. 2004 Dec; 66(6):1372-82. PMID: 15331769

Galkina SI, Dormeneva EV, Bachschmid M, Pushkareva MA, Sud'ina GF, Ullrich V. Endothelium-leukocyte interactions under the influence of the superoxide-nitrogen monoxide system. Med Sci Monit. 2004 Sep; 10(9):BR307-16. PMID: 15328475

Daiber A, Bachschmid M, Beckman JS, Munzel T, Ullrich V. The impact of metal catalysis on protein tyrosine nitration by peroxynitrite. Biochem Biophys Res Commun. 2004 May 7; 317(3):873-81. PMID: 15081421

Bachschmid M, van der Loo B, Schüler K, Labugger R, Thurau S, Eto M, Kilo J, Hölz R, Lüscher TF, Ullrich V. Oxidative stress-associated vascular aging is independent of the protein kinase C/NAD(P)H oxidase pathway. Arch Gerontol Geriatr. 2004 Mar-Apr; 38(2):181-90. PMID: 14698497

Schildknecht S, Bachschmid M, Baumann A, Ullrich V. COX-2 inhibitors selectively block prostacyclin synthesis in endotoxin-exposed vascular smooth muscle cells. FASEB J. 2004 Apr; 18(6):757-9. PMID: 14977876

van der Loo B, Labugger R, Aebischer CP, Bachschmid M, Spitzer V, Kilo J, Altwegg L, Ullrich V, Lüscher TF. Age-related changes of vitamin A status. J Cardiovasc Pharmacol. 2004 Jan; 43(1):26-30. PMID: 14668564

Hink U, Oelze M, Kolb P, Bachschmid M, Zou MH, Daiber A, Mollnau H, August M, Baldus S, Tsilimingas N, Walter U, Ullrich V, Münzel T. Role for peroxynitrite in the inhibition of prostacyclin synthase in nitrate tolerance. J Am Coll Cardiol. 2003 Nov 19; 42(10):1826-34. PMID: 14642695

Daiber A, Bachschmid M, Kavaklí C, Frein D, Wendt M, Ullrich V, Munzel T. A new pitfall in detecting biological end products of nitric oxide-nitration, nitros(yl)ation and nitrite/nitrate artefacts during freezing. Nitric Oxide. 2003 Aug; 9(1):44-52. PMID: 14559431

van der Loo B, Bachschmid M, Spitzer V, Brey L, Ullrich V, Lüscher TF. Decreased plasma and tissue levels of vitamin C in a rat model of aging: implications for antioxidative defense. Biochem Biophys Res Commun. 2003 Apr 4; 303(2):483-7. PMID: 12659843

Bachschmid M, Thurau S, Zou MH, Ullrich V. Endothelial cell activation by endotoxin involves superoxide/NO-mediated nitration of prostacyclin synthase and thromboxane receptor stimulation. FASEB J. 2003 May; 17(8):914-6. PMID: 12670882

Cosentino F, Eto M, De Paolis P, van der Loo B, Bachschmid M, Ullrich V, Kouroedov A, Delli Gatti C, Joch H, Volpe M, Lüscher TF. High glucose causes upregulation of cyclooxygenase-2 and alters prostanoid profile in human endothelial cells: role of protein kinase C and reactive oxygen species. Circulation. 2003 Feb 25; 107(7):1017-23. PMID: 12600916

Schmidt P, Youhnovski N, Daiber A, Balan A, Arsic M, Bachschmid M, Przybylski M, Ullrich V. Specific nitration at tyrosine 430 revealed by high resolution mass spectrometry as basis for redox regulation of bovine prostacyclin synthase. J Biol Chem. 2003 Apr 11; 278(15):12813-9. PMID: 12562775

van der Loo B, Labugger R, Aebischer CP, Skepper JN, Bachschmid M, Spitzer V, Kilo J, Altwegg L, Ullrich V, Lüscher TF. Cardiovascular aging is associated with vitamin E increase. Circulation. 2002 Apr 9; 105(14):1635-8. PMID: 11940539

Ullrich V, Zou MH, Bachschmid M. New physiological and pathophysiological aspects on the thromboxane A(2)-prostacyclin regulatory system. Biochim Biophys Acta. 2001 May 31; 1532(1-2):1-14. PMID: 11420169

van der Loo B, Labugger R, Skepper JN, Bachschmid M, Kilo J, Powell JM, Palacios-Callender M, Erusalimsky JD, Quaschning T, Malinski T, Gygi D, Ullrich V, Lüscher TF. Enhanced peroxynitrite formation is associated with vascular aging. J Exp Med. 2000 Dec 18; 192(12):1731-44. PMID: 11120770; PMCID: PMC2213492

Ullrich V, Bachschmid M. Superoxide as a messenger of endothelial function. Biochem Biophys Res Commun. 2000 Nov 11; 278(1):1-8. PMID: 11071846

Daiber A, Zou MH, Bachschmid M, Ullrich V. Ebselen as a peroxynitrite scavenger in vitro and ex vivo. Biochem Pharmacol. 2000 Jan 15; 59(2):153-60. PMID: 10810449

Zou MH, Bachschmid M. Hypoxia-reoxygenation triggers coronary vasospasm in isolated bovine coronary arteries via tyrosine nitration of prostacyclin synthase. J Exp Med. 1999 Jul 5; 190(1):135-9. PMID: 10429677; PMCID: PMC2195551

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Dr. Bachschmid has trained multiple graduate and post graduate students in the past. He has vast experience in training students, serving on graduate education programs as faculty including Graduate Medical Sciences and the Molecular and Translational Medicine. Through these programs he has served on several thesis committees. His training style is fostering an open environment and reserve as much time as possible for his trainees. His office door is always open and trainees are welcome to consult him on research or interpersonal problems. He regularly enters the lab to discuss research with his mentees, and will train them in specialized techniques at the bench as needed. He organizes weekly section meeting for the basic research operation of the Vascular Biology Section in which the group discusses laboratory and organizational matters. Every two weeks the section has a journal club, in which trainees present their data or discuss latest publications. For his lab, we have weekly lab meetings (usually 2h duration) to discuss as a group the research progress. He also has weekly individual face-to-face meetings with every trainees to evaluate progress and discuss the next steps and novel ideas.

Available to Mentor as: (Review Mentor Role Definitions):

Advisor
Career Mentor
Project Mentor
Research / Scholarly Mentor

Contact for Mentoring:

Email (see 'Contact Info')