Hemant K. Roy, MD
Professor
Boston University School of Medicine
Dept of Medicine
Gastroenterology

MD, Northwestern University School of Medicine



Dr. Roy joined the faculty in 2013. He completed his medical degree from Northwestern University with distinction and completed internal medicine residency at Beth Isreal followed by GI Fellowship at University of Chicago.

Dr. Roy’s research interests center on GI cancer risk stratification using intermediate biomarkers of field carcinogenesis. He has been involved in the development and clinical implementation of a variety of biophotonic techniques for risk stratification encompassing both fiberoptic probes and cytological based techniques and these are complemented by a variety of molecular markers including microRNAs.

This has served as a platform for assessing risk modification via chemoprevention and applied to a number of non-GI malignancies including lung and ovarian cancer. Dr. Roy is a fellow of the American Gastroenterological Association and member of the Early Detection Research Network and the Cancer Biomarkers Study Section of the NCI,

More clinically, his interests are in high risk colon cancer syndromes and role of gender in colorectal cancer screening. Throughout his career he has also been involved in teaching receiving numerous awards in this regard.

Section Chief of Medicine in Gastroenterology
Boston University School of Medicine
Medicine
Gastroenterology




Area B: Minimally Intrusive Colorectal Cancer Risk Stratification with Nanocytology: Targeting Un…
09/30/2017 - 08/31/2020 (PI)
NIH-NCI
1R33CA225323-01

Buccal Nanocytological Risk Stratification to Personalize Lung Cancer Screening
09/01/2016 - 08/31/2018 (PI)
Nanocytomics, LLC. NIH-DHHS
1R44CA206844-01A1

Risk-stratification of Prostate Cancers via Field Carcinogenesis Nanocytology
08/14/2015 - 07/31/2018 (PI)
Northwestern University NIH-NCI

Nanoscale/Molecular Analysis of Fecal Colonocytes for Colorectal Cancer Screening
01/01/2013 - 06/30/2018 (PI)
Northwestern University NIH-NCI

Towards Development of an in vitro Assay to Personalize Colonic Chemoprevention
04/01/2015 - 03/31/2018 (PI)
NIH-NCI

Biophotonics to Couple Pancreatic with Upper GI Screening via Ultrathin Endoscopy
01/01/2015 - 12/31/2017 (PI)
Northwestern University NIH-NCI

Transforming Colorectal Cancer Screening through Multimodal Spectral Markers
09/13/2013 - 11/30/2017 (PI)
NIH-NCI

Colon cancer risk-stratification via optical analysis of rectal ultrastructure
09/01/2016 - 08/31/2017 (PI)
American BioOptics, LLC NIH-NCI

High-throughput molecular-specific cell nanocytology for cancer screening
09/01/2016 - 08/31/2017 (PI)
Northwestern University NIH-NIBIB

Optical Nanoscale Analysis of Buccal Cells: Transforming Lung Cancer Screening
01/01/2013 - 07/31/2017 (PI)
Northwestern University NIH-NCI

Showing 10 of 21 results. Show All Results


Yr Title Project-Sub Proj Pubs
2017 Risk-stratification of Prostate Cancers via Field Carcinogenesis Nanocytology 5R01CA200064-03 5
2017 Biophotonics to Couple Pancreatic with Upper GI Screening via Ultrathin Endoscopy 5R01CA183101-03 3
2016 Risk-stratification of Prostate Cancers via Field Carcinogenesis Nanocytology 5R01CA200064-02 5
2016 Towards Development of an in vitro Assay to Personalize Colonic Chemoprevention 5R03CA195143-02 1
2016 Biophotonics to Couple Pancreatic with Upper GI Screening via Ultrathin Endoscopy 5R01CA183101-02 3
2016 Nanoscale/Molecular analysis of Fecal Colonocytes for Colorectal Cancer Screening 4R01CA165309-05 23
2015 Risk-stratification of Prostate Cancers via Field Carcinogenesis Nanocytology 1R01CA200064-01 5
2015 Towards Development of an in vitro Assay to Personalize Colonic Chemoprevention 1R03CA195143-01 1
2015 Biophotonics to Couple Pancreatic with Upper GI Screening via Ultrathin Endoscopy 1R01CA183101-01A1 3
2015 Transforming Colorectal Cancer Screening through Multimodal Spectral Markers 5R01CA156186-06 21
Showing 10 of 51 results. Show All Results
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Bauer GM, Stypula-Cyrus Y, Subramanian H, Cherkezyan L, Viswanathan P, Zhang D, Iyengar R, Bagalkar S, Derbas J, Graff T, Gladstein S, Almassalha LM, Chandler JE, Roy HK, Backman V. The transformation of the nuclear nanoarchitecture in human field carcinogenesis. Future Sci OA. 2017 Aug; 3(3):FSO206. PMID: 28884003.
  2. Cruz MD, Ledbetter S, Chowdhury S, Tiwari AK, Momi N, Wali RK, Bliss C, Huang C, Lichtenstein D, Bhattacharya S, Varma-Wilson A, Backman V, Roy HK. Metabolic reprogramming of the premalignant colonic mucosa is an early event in carcinogenesis. Oncotarget. 2017 Mar 28; 8(13):20543-20557.View Related Profiles. PMID: 28423551; DOI: 10.18632/oncotarget.16129;.
  3. Shao D, Han J, Hou X, Fry J, Behring JB, Seta F, Long MT, Roy HK, Cohen RA, Matsui R, Bachschmid MM. Glutaredoxin-1 Deficiency Causes Fatty Liver and Dyslipidemia by Inhibiting Sirtuin-1. Antioxid Redox Signal. 2017 Aug 20; 27(6):313-327.View Related Profiles. PMID: 27958883; DOI: 10.1089/ars.2016.6716;.
  4. Drew DA, Chin SM, Gilpin KK, Parziale M, Pond E, Schuck MM, Stewart K, Flagg M, Rawlings CA, Backman V, Carolan PJ, Chung DC, Colizzo FP, Freedman M, Gala M, Garber JJ, Huttenhower C, Kedrin D, Khalili H, Kwon DS, Markowitz SD, Milne GL, Nishioka NS, Richter JM, Roy HK, Staller K, Wang M, Chan AT. ASPirin Intervention for the REDuction of colorectal cancer risk (ASPIRED): a study protocol for a randomized controlled trial. Trials. 2017 Feb 01; 18(1):50. PMID: 28143522; DOI: 10.1186/s13063-016-1744-z;.
  5. Krishn SR, Kaur S, Sheinin YM, Smith LM, Gautam SK, Patel A, Jain M, Juvvigunta V, Pai P, Lazenby AJ, Roy HK, Batra SK. Mucins and associated O-glycans based immunoprofile for stratification of colorectal polyps: clinical implication for improved colon surveillance. Oncotarget. 2017 Jan 24; 8(4):7025-7038. PMID: 27705923; DOI: 10.18632/oncotarget.12347;.
  6. Chowdhury S, Roy HK. The genetics and molecular biology of colonic neoplasia: practical implications for the clinician. Curr Opin Gastroenterol. 2017 Jan; 33(1):47-52.View Related Profiles. PMID: 27798442; DOI: 10.1097/MOG.0000000000000323;.
  7. Calderwood AH, Lasser KE, Roy HK. Colon adenoma features and their impact on risk of future advanced adenomas and colorectal cancer. World J Gastrointest Oncol. 2016 Dec 15; 8(12):826-834.View Related Profiles. PMID: 28035253; DOI: 10.4251/wjgo.v8.i12.826;.
  8. Almassalha LM, Bauer GM, Chandler JE, Gladstein S, Cherkezyan L, Stypula-Cyrus Y, Weinberg S, Zhang D, Thusgaard Ruhoff P, Roy HK, Subramanian H, Chandel NS, Szleifer I, Backman V. Label-free imaging of the native, living cellular nanoarchitecture using partial-wave spectroscopic microscopy. Proc Natl Acad Sci U S A. 2016 Oct 18; 113(42):E6372-E6381. PMID: 27702891.
  9. Subramanian H, Viswanathan P, Cherkezyan L, Iyengar R, Rozhok S, Verleye M, Derbas J, Czarnecki J, Roy HK, Backman V. Procedures for risk-stratification of lung cancer using buccal nanocytology. Biomed Opt Express. 2016 Sep 01; 7(9):3795-3810. PMID: 27699138.
  10. Almassalha LM, Bauer GM, Chandler JE, Gladstein S, Szleifer I, Roy HK, Backman V. The Greater Genomic Landscape: The Heterogeneous Evolution of Cancer. Cancer Res. 2016 Oct 01; 76(19):5605-5609. PMID: 27550448.
Showing 10 of 131 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 131 publications over 22 distinct years, with a maximum of 13 publications in 2008

YearPublications
19931
19942
19954
19971
19991
20014
20022
20033
20045
20058
20069
20075
200813
20098
201010
20119
201212
20138
20148
20158
20164
20176
Contact for Mentoring:


650 Albany St Evans Biomed Research Ctr
Boston MA 02118
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