Hemant K. Roy, MD
Boston University School of Medicine
Dept of Medicine

MD, Northwestern University School of Medicine

Dr. Roy joined the faculty in 2013. He completed his medical degree from Northwestern University with distinction and completed internal medicine residency at Beth Isreal followed by GI Fellowship at University of Chicago.

Dr. Roy’s research interests center on GI cancer risk stratification using intermediate biomarkers of field carcinogenesis. He has been involved in the development and clinical implementation of a variety of biophotonic techniques for risk stratification encompassing both fiberoptic probes and cytological based techniques and these are complemented by a variety of molecular markers including microRNAs.

This has served as a platform for assessing risk modification via chemoprevention and applied to a number of non-GI malignancies including lung and ovarian cancer. Dr. Roy is a fellow of the American Gastroenterological Association and member of the Early Detection Research Network and the Cancer Biomarkers Study Section of the NCI,

More clinically, his interests are in high risk colon cancer syndromes and role of gender in colorectal cancer screening. Throughout his career he has also been involved in teaching receiving numerous awards in this regard.

Section Chief of Medicine in Gastroenterology
Boston University School of Medicine

Area B: Minimally Intrusive Colorectal Cancer Risk Stratification with Nanocytology: Targeting Un…
09/30/2017 - 08/31/2020 (PI)

Biophotonics to Couple Pancreatic with Upper GI Screening via Ultrathin Endoscopy
01/01/2015 - 12/31/2018 (PI)
Northwestern University NIH-NCI

Buccal Nanocytological Risk Stratification to Personalize Lung Cancer Screening
09/01/2016 - 08/31/2018 (PI)
Nanocytomics, LLC. NIH-DHHS

Colon cancer risk-stratification via optical analysis of rectal ultrastructure
09/01/2016 - 08/31/2018 (PI)
American BioOptics, LLC NIH-NCI

Risk-stratification of Prostate Cancers via Field Carcinogenesis Nanocytology
08/14/2015 - 07/31/2018 (PI)
Northwestern University NIH-NCI

Nanoscale/Molecular Analysis of Fecal Colonocytes for Colorectal Cancer Screening
01/01/2013 - 06/30/2018 (PI)
Northwestern University NIH-NCI

Towards Development of an in vitro Assay to Personalize Colonic Chemoprevention
04/01/2015 - 03/31/2018 (PI)

Transforming Colorectal Cancer Screening through Multimodal Spectral Markers
09/13/2013 - 11/30/2017 (PI)

High-throughput molecular-specific cell nanocytology for cancer screening
09/01/2016 - 08/31/2017 (PI)
Northwestern University NIH-NIBIB

Optical Nanoscale Analysis of Buccal Cells: Transforming Lung Cancer Screening
01/01/2013 - 07/31/2017 (PI)
Northwestern University NIH-NCI

Showing 10 of 21 results. Show All Results

Yr Title Project-Sub Proj Pubs
2018 Translating buccal nanocytology for lung cancer screening into clinical practice 1R01CA225002-01A1
2018 Reducing Cancer Transcriptional Heterogeneity through Regulation of Chromatin Structure 1R01CA228272-01
2018 Microvasculature in Colon Field Carcinogenesis: Clinical-Biological Implications 1R01CA224911-01A1
2018 Biophotonics to Couple Pancreatic with Upper GI Screening via Ultrathin Endoscopy 5R01CA183101-04 3
2017 Area B: Minimally Intrusive Colorectal Cancer Risk Stratification with Nanocytology: Targeting Underscreened Populations 1R33CA225323-01
2017 Risk-stratification of Prostate Cancers via Field Carcinogenesis Nanocytology 5R01CA200064-03 5
2017 Biophotonics to Couple Pancreatic with Upper GI Screening via Ultrathin Endoscopy 5R01CA183101-03 3
2016 Risk-stratification of Prostate Cancers via Field Carcinogenesis Nanocytology 5R01CA200064-02 5
2016 Towards Development of an in vitro Assay to Personalize Colonic Chemoprevention 5R03CA195143-02 1
2016 Biophotonics to Couple Pancreatic with Upper GI Screening via Ultrathin Endoscopy 5R01CA183101-02 3
Showing 10 of 56 results. Show All Results
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Eshein A, Radosevich A, Gould B, Wu W, Konda V, Yang L, Koons A, Feder S, Valuckaite V, Roy H, Backman V, Nguyen TQ. Fully automated fiber-based optical spectroscopy system for use in a clinical setting. J Biomed Opt. 2018 Jul; 23(7):1-10. PMID: 29981224.
  2. Kalman R, Stawarz A, Nunes D, Zhang D, Dela Cruz MA, Mohanty A, Subramanian H, Backman V, Roy HK. Biophotonic detection of high order chromatin alterations in field carcinogenesis predicts risk of future hepatocellular carcinoma: A pilot study. PLoS One. 2018; 13(5):e0197427. PMID: 29771950.
  3. Wali RK, Bianchi L, Kupfer S, De La Cruz M, Jovanovic B, Weber C, Goldberg MJ, Rodriguez LM, Bergan R, Rubin D, Tull MB, Richmond E, Parker B, Khan S, Roy HK. Prevention of colonic neoplasia with polyethylene glycol: A short term randomized placebo-controlled double-blinded trial. PLoS One. 2018; 13(4):e0193544. PMID: 29617381.
  4. Mohapatra SS, Batra SK, Bharadwaj S, Bouvet M, Cosman B, Goel A, Jogunoori W, Kelley MJ, Mishra L, Mishra B, Mohapatra S, Patel B, Pisegna JR, Raufman JP, Rao S, Roy H, Scheuner M, Singh S, Vidyarthi G, White J. Precision Medicine for CRC Patients in the Veteran Population: State-of-the-Art, Challenges and Research Directions. Dig Dis Sci. 2018 05; 63(5):1123-1138. PMID: 29572615.
  5. Gladstein S, Damania D, Almassalha LM, Smith LT, Gupta V, Subramanian H, Rex DK, Roy HK, Backman V. Correlating colorectal cancer risk with field carcinogenesis progression using partial wave spectroscopic microscopy. Cancer Med. 2018 May; 7(5):2109-2120. PMID: 29573208.
  6. Datta S, Sherva RM, De La Cruz M, Long MT, Roy P, Backman V, Chowdhury S, Roy HK. Single Nucleotide Polymorphism Facilitated Down-Regulation of the Cohesin Stromal Antigen-1: Implications for Colorectal Cancer Racial Disparities. Neoplasia. 2018 Mar; 20(3):289-294.View Related Profiles. PMID: 29471289; DOI: 10.1016/j.neo.2018.01.003;.
  7. Roy P, Chowdhury S, Roy HK. Exercise-induced myokines as emerging therapeutic agents in colorectal cancer prevention and treatment. Future Oncol. 2018 02; 14(4):309-312.View Related Profiles. PMID: 29318900.
  8. Almassalha LM, Bauer GM, Wu W, Cherkezyan L, Zhang D, Kendra A, Gladstein S, Chandler JE, VanDerway D, Seagle BL, Ugolkov A, Billadeau DD, O'Halloran TV, Mazar AP, Roy HK, Szleifer I, Shahabi S, Backman V. Macrogenomic engineering via modulation of the scaling of chromatin packing density. Nat Biomed Eng. 2017 Nov; 1(11):902-913. PMID: 29450107.
  9. Bauer GM, Stypula-Cyrus Y, Subramanian H, Cherkezyan L, Viswanathan P, Zhang D, Iyengar R, Bagalkar S, Derbas J, Graff T, Gladstein S, Almassalha LM, Chandler JE, Roy HK, Backman V. The transformation of the nuclear nanoarchitecture in human field carcinogenesis. Future Sci OA. 2017 Aug; 3(3):FSO206. PMID: 28884003.
  10. Datta S, Chowdhury S, Roy HK. Metabolism, microbiome and colorectal cancer. Aging (Albany NY). 2017 Apr; 9(4):1086-1087.View Related Profiles. PMID: 28455972; DOI: 10.18632/aging.101234;.
Showing 10 of 147 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 147 publications over 24 distinct years, with a maximum of 14 publications in 2008

Contact for Mentoring:

650 Albany St Evans Biomed Research Ctr
Boston MA 02118
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