Keywords
Last Name

David P. Nunes, MD

TitleAssociate Professor
InstitutionBoston University School of Medicine
DepartmentMedicine
DivisionGastroenterology
Address85 E. Concord St
Boston MA 02118
Phone(617) 638-6525
ORCID ORCID Icon0000-0002-6808-2247
Other Positions
TitleActive Staff Privileges
InstitutionBoston Medical Center
DepartmentMedicine

 Research Expertise & Professional Interests
Expertise includes: Clinical liver disease - interest in viral hepatitis; Evaluation and management of liver lesions.

 Self-Described Keywords
  • Hepatitis B
  • Hepatitis C
  • Liver fibrosis
 Publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Baranoski AS, Cotton D, Heeren T, Nunes D, Kubiak RW, Horsburgh CR. Clinical Liver Disease Progression Among Hepatitis C-Infected Drug Users With CD4 Cell Count Less Than 200 Cells/mm(3) Is More Pronounced Among Women Than Men. Open Forum Infect Dis. 2016 Jan; 3(1):ofv214. PMID: 26955643.
    View in: PubMed
  2. Anderson JP, Horsburgh CR, Williams PL, Tchetgen Tchetgen EJ, Nunes D, Cotton D, Seage GR. CD4 recovery on antiretroviral therapy is associated with decreased progression to liver disease among hepatitis C virus-infected injecting drug users. Open Forum Infect Dis. 2015 Jan; 2(1):ofv019. PMID: 26034769.
    View in: PubMed
  3. Fuster D, Cheng DM, Quinn EK, Nunes D, Saitz R, Samet JH, Tsui JI. Chronic hepatitis C virus infection is associated with all-cause and liver-related mortality in a cohort of HIV-infected patients with alcohol problems. Addiction. 2014 Jan; 109(1):62-70. PMID: 24112091.
    View in: PubMed
  4. Okafor PN, Nunes DP, Farraye FA. Pneumocystis jiroveci pneumonia in inflammatory bowel disease: when should prophylaxis be considered? Inflamm Bowel Dis. 2013 Jul; 19(8):1764-71. PMID: 23615530.
    View in: PubMed
  5. Fuster D, Tsui JI, Cheng DM, Quinn EK, Armah KA, Nunes D, Freiberg MS, Samet JH. Interleukin-6 is associated with noninvasive markers of liver fibrosis in HIV-infected patients with alcohol problems. AIDS Res Hum Retroviruses. 2013 Aug; 29(8):1110-6. PMID: 23601055.
    View in: PubMed
  6. Fuster D, Tsui JI, Cheng DM, Quinn EK, Bridden C, Nunes D, Libman H, Saitz R, Samet JH. Impact of lifetime alcohol use on liver fibrosis in a population of HIV-infected patients with and without hepatitis C coinfection. Alcohol Clin Exp Res. 2013 Sep; 37(9):1527-35. PMID: 23647488.
    View in: PubMed
  7. Pereira C, Yalçin A, Cretich M, Chiari M, Unlü MS, Nunes D, Bergstein DA. Synergetic chemiluminescence and label-free dual detection for developing a hepatitis protein array. J Immunol Methods. 2011 Aug 31; 371(1-2):159-64. PMID: 21718699.
    View in: PubMed
  8. Nunes D, Fleming C, Offner G, Craven D, Fix O, Heeren T, Koziel MJ, Graham C, Tumilty S, Skolnik P, Stuver S, Horsburgh CR, Cotton D. Noninvasive markers of liver fibrosis are highly predictive of liver-related death in a cohort of HCV-infected individuals with and without HIV infection. Am J Gastroenterol. 2010 Jun; 105(6):1346-53. PMID: 20179698.
    View in: PubMed
  9. Pungpapong S, Nunes DP, Krishna M, Nakhleh R, Chambers K, Ghabril M, Dickson RC, Hughes CB, Steers J, Nguyen JH, Keaveny AP. Serum fibrosis markers can predict rapid fibrosis progression after liver transplantation for hepatitis C. Liver Transpl. 2008 Sep; 14(9):1294-302. PMID: 18756457.
    View in: PubMed
  10. Sullivan LE, Saitz R, Cheng DM, Libman H, Nunes D, Samet JH. The impact of alcohol use on depressive symptoms in human immunodeficiency virus-infected patients. Addiction. 2008 Sep; 103(9):1461-7. PMID: 18637000.
    View in: PubMed
  11. Walley AY, Cheng DM, Libman H, Nunes D, Horsburgh CR, Saitz R, Samet JH. Recent drug use, homelessness and increased short-term mortality in HIV-infected persons with alcohol problems. AIDS. 2008 Jan 30; 22(3):415-20. PMID: 18195568.
    View in: PubMed
  12. Reed C, Stuver SO, Tumilty S, Nunes D, Murray JE, Graham CS, James Koziel M, Craven DE, Skolnik PR, Horsburgh CR. Predictors of treatment for hepatitis C virus (HCV) infection in drug users. Subst Abus. 2008; 29(1):5-15. PMID: 19042314.
    View in: PubMed
  13. Samet JH, Cheng DM, Libman H, Nunes DP, Alperen JK, Saitz R. Alcohol consumption and HIV disease progression. J Acquir Immune Defic Syndr. 2007 Oct 1; 46(2):194-9. PMID: 17667330.
    View in: PubMed
  14. Cheng DM, Nunes D, Libman H, Vidaver J, Alperen JK, Saitz R, Samet JH. Impact of hepatitis C on HIV progression in adults with alcohol problems. Alcohol Clin Exp Res. 2007 May; 31(5):829-36. PMID: 17403066.
    View in: PubMed
  15. Campos NG, Salomon JA, Servoss JC, Nunes DP, Samet JH, Freedberg KA, Goldie SJ. Cost-effectiveness of treatment for hepatitis C in an urban cohort co-infected with HIV. Am J Med. 2007 Mar; 120(3):272-9. PMID: 17349451.
    View in: PubMed
  16. Tsui JI, Saitz R, Cheng DM, Nunes D, Libman H, Alperen JK, Samet JH. Awareness of hepatitis C diagnosis is associated with less alcohol use among persons co-infected with HIV. J Gen Intern Med. 2007 Jun; 22(6):822-5. PMID: 17503108.
    View in: PubMed
  17. Graham CS, Wells A, Edwards EM, Herren T, Tumilty S, Stuver SO, Samet JH, Nunes D, Horsburgh CR, Koziel MJ. Effect of exposure to injection drugs or alcohol on antigen-specific immune responses in HIV and hepatitis C virus coinfection. J Infect Dis. 2007 Mar 15; 195(6):847-56. PMID: 17299715.
    View in: PubMed
  18. Nunes D, Saitz R, Libman H, Cheng DM, Vidaver J, Samet JH. Barriers to treatment of hepatitis C in HIV/HCV-coinfected adults with alcohol problems. Alcohol Clin Exp Res. 2006 Sep; 30(9):1520-6. PMID: 16930214.
    View in: PubMed
  19. Palepu A, Cheng DM, Kim T, Nunes D, Vidaver J, Alperen J, Saitz R, Samet JH. Substance abuse treatment and receipt of liver specialty care among persons coinfected with HIV/HCV who have alcohol problems. J Subst Abuse Treat. 2006 Dec; 31(4):411-7. PMID: 17084795.
    View in: PubMed
  20. Libman H, Saitz R, Nunes D, Cheng DM, Richardson JM, Vidaver J, Alperen JK, Samet JH. Hepatitis C infection is associated with depressive symptoms in HIV-infected adults with alcohol problems. Am J Gastroenterol. 2006 Aug; 101(8):1804-10. PMID: 16780562.
    View in: PubMed
  21. Nunes D, Fleming C, Offner G, O'Brien M, Tumilty S, Fix O, Heeren T, Koziel M, Graham C, Craven DE, Stuver S, Horsburgh CR. HIV infection does not affect the performance of noninvasive markers of fibrosis for the diagnosis of hepatitis C virus-related liver disease. J Acquir Immune Defic Syndr. 2005 Dec 15; 40(5):538-44. PMID: 16284529.
    View in: PubMed
  22. Li X, Wang L, Nunes DP, Troxler RF, Offner GD. Suppression of MUC1 synthesis downregulates expression of the epidermal growth factor receptor. Cancer Biol Ther. 2005 Sep; 4(9):968-73. PMID: 16082192.
    View in: PubMed
  23. Fleming CA, Tumilty S, Murray JE, Nunes D. Challenges in the treatment of patients coinfected with HIV and hepatitis C virus: need for team care. Clin Infect Dis. 2005 Apr 15; 40 Suppl 5:S349-54. PMID: 15768347.
    View in: PubMed
  24. Nunes D, Schroy PC. Another step forward: treating HCV infection in HIV coinfected patients. Gastroenterology. 2005 Feb; 128(2):513-5. PMID: 15685568.
    View in: PubMed
  25. Graham CS, Curry M, He Q, Afdhal N, Nunes D, Fleming C, Horsburgh R, Craven D, Sherman KE, Koziel MJ. Comparison of HCV-specific intrahepatic CD4+ T cells in HIV/HCV versus HCV. Hepatology. 2004 Jul; 40(1):125-32. PMID: 15239095.
    View in: PubMed
  26. Afdhal NH, Nunes D. Evaluation of liver fibrosis: a concise review. Am J Gastroenterol. 2004 Jun; 99(6):1160-74. PMID: 15180741.
    View in: PubMed
  27. Fleming CA, Christiansen D, Nunes D, Heeren T, Thornton D, Horsburgh CR, Koziel MJ, Graham C, Craven DE. Health-related quality of life of patients with HIV disease: impact of hepatitis C coinfection. Clin Infect Dis. 2004 Feb 15; 38(4):572-8. PMID: 14765352.
    View in: PubMed
  28. Li X, Wang L, Nunes DP, Troxler RF, Offner GD. Pro-inflammatory cytokines up-regulate MUC1 gene expression in oral epithelial cells. J Dent Res. 2003 Nov; 82(11):883-7. PMID: 14578499.
    View in: PubMed
  29. Fleming CA, Craven DE, Thornton D, Tumilty S, Nunes D. Hepatitis C virus and human immunodeficiency virus coinfection in an urban population: low eligibility for interferon treatment. Clin Infect Dis. 2003 Jan 1; 36(1):97-100. PMID: 12491208.
    View in: PubMed
  30. Liu B, Lague JR, Nunes DP, Toselli P, Oppenheim FG, Soares RV, Troxler RF, Offner GD. Expression of membrane-associated mucins MUC1 and MUC4 in major human salivary glands. J Histochem Cytochem. 2002 Jun; 50(6):811-20. PMID: 12019297.
    View in: PubMed
  31. O'Brien MJ, Keating NM, Elderiny S, Cerda S, Keaveny AP, Afdhal NH, Nunes DP. An assessment of digital image analysis to measure fibrosis in liver biopsy specimens of patients with chronic hepatitis C. Am J Clin Pathol. 2000 Nov; 114(5):712-8. PMID: 11068544.
    View in: PubMed
  32. Craven DE, Nunes DP. Managing hepatitis C infection in HIV-positive patients. AIDS Clin Care. 2000 Sep; 12(9):71-5, 78. PMID: 12170952.
    View in: PubMed
  33. Nunes D, Piliero PJ. Antiretroviral rounds. A co-infection treatment dilemma. AIDS Clin Care. 2000 Jul; 12(7):58-9. PMID: 12170957.
    View in: PubMed
  34. Keaveny AP, Offner GD, Bootle E, Nunes DP. No significant difference in antigenicity or tissue transglutaminase substrate specificity of Irish and US wheat gliadins. Dig Dis Sci. 2000 Apr; 45(4):755-62. PMID: 10759247.
    View in: PubMed
  35. Fenlon HM, Nunes DP, Schroy PC, Barish MA, Clarke PD, Ferrucci JT. A comparison of virtual and conventional colonoscopy for the detection of colorectal polyps. N Engl J Med. 1999 Nov 11; 341(20):1496-503. PMID: 10559450.
    View in: PubMed
  36. Nunes DP, Afdhal NH, Offner GD. A recombinant bovine gallbladder mucin polypeptide binds biliary lipids and accelerates cholesterol crystal appearance time. Gastroenterology. 1999 Apr; 116(4):936-42. PMID: 10092316.
    View in: PubMed
  37. Fenlon HM, McAneny DB, Nunes DP, Clarke PD, Ferrucci JT. Occlusive colon carcinoma: virtual colonoscopy in the preoperative evaluation of the proximal colon. Radiology. 1999 Feb; 210(2):423-8. PMID: 10207425.
    View in: PubMed
  38. Fenlon HM, Nunes DP, Clarke PD, Ferrucci JT. Colorectal neoplasm detection using virtual colonoscopy: a feasibility study. Gut. 1998 Dec; 43(6):806-11. PMID: 9824608.
    View in: PubMed
  39. Offner GD, Nunes DP, Keates AC, Afdhal NH, Troxler RF. The amino-terminal sequence of MUC5B contains conserved multifunctional D domains: implications for tissue-specific mucin functions. Biochem Biophys Res Commun. 1998 Oct 9; 251(1):350-5. PMID: 9790959.
    View in: PubMed
  40. Liu B, Offner GD, Nunes DP, Oppenheim FG, Troxler RF. MUC4 is a major component of salivary mucin MG1 secreted by the human submandibular gland. Biochem Biophys Res Commun. 1998 Sep 29; 250(3):757-61. PMID: 9784419.
    View in: PubMed
  41. Raj V, Nunes D. Image of the month. Fascioliasis. Gastroenterology. 1998 May; 114(5):872, 1116. PMID: 10465626.
    View in: PubMed
  42. Afdhal NH, Keaveny AP, Cohen SB, Nunes DP, Maldonado N, O'Brien M, Stone PJ. Urinary assays for desmosine and hydroxylysylpyridinoline in the detection of cirrhosis. J Hepatol. 1997 Dec; 27(6):993-1002. PMID: 9453424.
    View in: PubMed
  43. Royster AP, Fenlon HM, Clarke PD, Nunes DP, Ferrucci JT. CT colonoscopy of colorectal neoplasms: two-dimensional and three-dimensional virtual-reality techniques with colonoscopic correlation. AJR Am J Roentgenol. 1997 Nov; 169(5):1237-42. PMID: 9353434.
    View in: PubMed
  44. Troxler RF, Iontcheva I, Oppenheim FG, Nunes DP, Offner GD. Molecular characterization of a major high molecular weight mucin from human sublingual gland. Glycobiology. 1997 Oct; 7(7):965-73. PMID: 9363439.
    View in: PubMed
  45. Keates AC, Nunes DP, Afdhal NH, Troxler RF, Offner GD. Molecular cloning of a major human gall bladder mucin: complete C-terminal sequence and genomic organization of MUC5B. Biochem J. 1997 May 15; 324 ( Pt 1):295-303. PMID: 9164870.
    View in: PubMed
  46. Dunzendorfer T, Nunes DP, Kasznica J. More intestinal worms on colonoscopy. Am J Gastroenterol. 1996 Aug; 91(8):1677-8. PMID: 8759705.
    View in: PubMed
  47. Afdhal NH, Ostrow JD, Koehler R, Niu N, Groen AK, Veis A, Nunes DP, Offner GD. Interaction of bovine gallbladder mucin and calcium-binding protein: effects on calcium phosphate precipitation. Gastroenterology. 1995 Nov; 109(5):1661-72. PMID: 7557151.
    View in: PubMed
  48. Afdhal NH, Niu N, Nunes DP, Bansil R, Cao XX, Gantz D, Small DM, Offner GD. Mucin-vesicle interactions in model bile: evidence for vesicle aggregation and fusion before cholesterol crystal formation. Hepatology. 1995 Sep; 22(3):856-65. PMID: 7657293.
    View in: PubMed
  49. Nunes DP, Keates AC, Afdhal NH, Offner GD. Bovine gall-bladder mucin contains two distinct tandem repeating sequences: evidence for scavenger receptor cysteine-rich repeats. Biochem J. 1995 Aug 15; 310 ( Pt 1):41-8. PMID: 7646470.
    View in: PubMed
  50. Courtney MG, Nunes DP, Bergin CF, O'Driscoll M, Trimble V, Keeling PW, Weir DG. Randomised comparison of olsalazine and mesalazine in prevention of relapses in ulcerative colitis. Lancet. 1992 May 23; 339(8804):1279-81. PMID: 1349676.
    View in: PubMed
  51. Nunes D, Kennedy NP, Weir DG. Treatment of peptic ulcer disease in the arthritic patient. Drugs. 1989 Sep; 38(3):451-61. PMID: 2680437.
    View in: PubMed
  52. Bourke S, Nunes D, Stafford F, Hurley G, Graham I. Percussion of the chest re-visited: a comparison of the diagnostic value of ausculatory and conventional chest percussion. Ir J Med Sci. 1989 Apr; 158(4):82-4. PMID: 2753659.
    View in: PubMed
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