Katya Ravid | Profiles RNS

Katya Ravid, DSc

Professor

Boston University School of Medicine

Dept of Medicine

Cardiovascular Medicine

PhD, Technion - Israel Institute of Technology
DSc, Technion - Israel Institute of Technology

Websites

	BU Interdisciplinary Biomedical Research Office
	Department of Medicine Faculty
	Evans Center for Interdisciplinary Biomedical Research
	Ravid Lab
	Master of Science Program in Biomedical Research Technology

ORCID : 0000-0002-9918-3024

Platelet aggregation plays a central role in thrombosis and hemostasis, which are central to vascular disease. In the platelet lineage, the early committed cells undergo a unique cell cycle leading to the formation of polyploid megakaryocytes prior to their fragmentation into platelets. Our research focuses on mechanisms that regulate lineage commitment and the subsequent steps of cellular maturation of bone marrow cells into polyploid megakaryocytes. We reported that polyploidy also develops in aging vascular cells, and in other cell types under stress, and mechanisms of control of polyploidy and its relevance to disease states are investigated. An ongoing related project involves the molecular characterization of platelet and vascular adenosine receptors, and exploration of their role in cellular function and lineage development. The systems used include primary bone marrow cultures, as well as transgenic and knock out mouse models.

Professor
Boston University School of Medicine
Biochemistry

Director
Boston University School of Medicine
Medicine
Evans Center for Interdisciplinary Biomedical Research

Director
Boston University
BU Interdisciplinary Biomedical Research Office

Director, Master of Science Program in Biomedical Research
Boston University School of Medicine
Medicine

Mentor for Graduate Medical Students
Boston University School of Medicine, Division of Graduate Medical Sciences

Center Faculty Member
Boston University School of Medicine
Cardiovascular Institute (Whitaker)

2016 Fulbright : Fulbright Research Scholar Award

2016-2017 Aarhus University, Denmark : International Advisory Board

2014 Weizmann Institute: Weizmann Institute Professorship Award

2014 American Association for the Advancement of Science: Elected Fellow

2013 Boston University School of Medicine: Robert Dawson Evans Special Recognition Teaching Award

2013-2016 American Society of Hematology: Chair, Thrombosis and Vascular Biology Scientific Committee

2011-2013 Gordon Research Conference-Cell Biology of Megakaryocytes and Platelets: Vice Chair & Chair

2009 University of Sydney : International Visiting Professor Fellowship Award

2006 Boston University School of Medicine : Educator of the Year Award, Graduate Medical Sciences

2000-2005 American Heart Association: Established Investigator Award

1997 American Heart Association: Grant-In-Aid Award for Young Investigators

1987 Weizmann Institute: Weizmann Postdoctoral Fellowship Award

1982 Technion: Gutwirth Prize for Outstanding Graduate Students

BU Sponsored Research
NIH RePORTER Sponsored Research

A path to thrombosis in primary myelofibrosis
12/24/2017 - 11/30/2021 (PI)
NIH/National Heart, Lung, and Blood Institute
1R01HL136363-01A1

Training Program in Cardiovascular Biology: Pre-Doctoral
12/01/2014 - 11/30/2019 (PI)
NIH/National Heart, Lung, and Blood Institute
5T32HL007969-13

Lysyl Oxidase Pharmacological Inhibition of Bone Marow Fibrosis
03/01/2016 - 10/31/2018 (PI)
Pharmaxis

Mechanisms Regulating Megakaryocyte Development
04/01/2012 - 09/30/2017 (PI)
NIH/National Heart, Lung, and Blood Institute
5R01HL080442-09

Nanoplatforms for Imaging Bone Marrow Fibrosis
10/01/2014 - 09/30/2016 (PI)
MPN Research Foundation

Mechanisms Regulating Megakaryocte Development
04/01/2012 - 03/31/2016 (PI)
NIH/National Heart, Lung, and Blood Institute
2R01HL080442-06A1

Training in Cardiovascular Biology: Predoctoral
07/01/2011 - 06/30/2014 (PI)
NIH/National Heart, Lung, and Blood Institute
5T32HL007969-09

Adenosine Receptors and Atherogenesis
04/01/2009 - 03/31/2014 (PI)
NIH/National Heart, Lung, and Blood Institute
5R01HL093149-04

The A2b Adenosine Receptor as Regulator of Type II Diabetes
09/30/1997 - 03/31/2013 (PI)
Boston Medical Center Corporation NIH NIDDK
5P30DK046200-20

Properties of Polypoloid Cells in a Model of Aging
06/01/2003 - 05/31/2005 (PI)
NIH/National Institute on Aging
1 R03 AG22623 01

Showing 10 of 12 results. Show All Results

Yr	Title	Project-Sub Proj	Pubs
2018	Mechanism of Bone Marrow Neoplasm-Induced Osteosclerosis	1R21AR072748-01
2018	A path to thrombosis in primary myelofibrosis	1R01HL136363-01A1
2018	Training Program in Cardiovascular Biology: Pre-Doctoral	5T32HL007969-14	45
2017	Training Program in Cardiovascular Biology: Pre-Doctoral	5T32HL007969-13	45
2016	Training Program in Cardiovascular Biology: Pre-Doctoral	5T32HL007969-12	45
2015	Mechanisms Regulating Megakaryocyte Development	5R01HL080442-09	14
2015	Training Program in Cardiovascular Biology: Pre-Doctoral	2T32HL007969-11	45
2014	Mechanisms Regulating Megakaryocyte Development	5R01HL080442-08	14
2013	2013 Cell Biology of Megakaryocytes and Platelets GRC &GRS	1R13HL117369-01
2013	Mechanisms Regulating Megakaryocyte Development	5R01HL080442-07	14

Showing 10 of 54 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

Koupenova M, Ravid K. Biology of Platelet Purinergic Receptors and Implications for Platelet Heterogeneity. Front Pharmacol. 2018; 9:37. PMID: 29441021.

Kolachalama VB, Shashar M, Alousi F, Shivanna S, Rijal K, Belghasem ME, Walker J, Matsuura S, Chang GH, Gibson CM, Dember LM, Francis JM, Ravid K, Chitalia VC. Uremic Solute-Aryl Hydrocarbon Receptor-Tissue Factor Axis Associates with Thrombosis after Vascular Injury in Humans. J Am Soc Nephrol. 2018 Mar; 29(3):1063-1072.View Related Profiles.

Francis, Jean
Ravid, Katya
Belghasem, Mostafa
Matsuura, Shinobu
Kolachalama, Vijaya
Chitalia, Vipul

PMID: 29343519; DOI: 10.1681/ASN.2017080929;.

Leiva O, Leon C, Kah Ng S, Mangin P, Gachet C, Ravid K. The role of extracellular matrix stiffness in megakaryocyte and platelet development and function. Am J Hematol. 2018 Mar; 93(3):430-441. PMID: 29247535.

Shashar M, Belghasem ME, Matsuura S, Walker J, Richards S, Alousi F, Rijal K, Kolachalama VB, Balcells M, Odagi M, Nagasawa K, Henderson JM, Gautam A, Rushmore R, Francis J, Kirchhofer D, Kolandaivelu K, Sherr DH, Edelman ER, Ravid K, Chitalia VC. Targeting STUB1-tissue factor axis normalizes hyperthrombotic uremic phenotype without increasing bleeding risk. Sci Transl Med. 2017 Nov 22; 9(417).View Related Profiles.

Gautam, Amitabh
Sherr, David
Francis, Jean
Henderson, Joel
Ravid, Katya
Belghasem, Mostafa
Matsuura, Shinobu
Kolachalama, Vijaya
Chitalia, Vipul

PMID: 29167396; DOI: 10.1126/scitranslmed.aam8475;.

Ravid K, Seta F, Center D, Waters G, Coleman D. Catalyzing Interdisciplinary Research and Training: Initial Outcomes and Evolution of the Affinity Research Collaboratives Model. Acad Med. 2017 Oct; 92(10):1399-1405.View Related Profiles.

Coleman, David
Center, David
Seta, Francesca
Ravid, Katya

PMID: 28445220.

Zhang A, Rijal K, Ng SK, Ravid K, Chitalia V. A mass spectrometric method for quantification of tryptophan-derived uremic solutes in human serum. J Biol Methods. 2017; 4(3).View Related Profiles.

Ravid, Katya
Chitalia, Vipul

PMID: 29707597.

Gordon CE, Chitalia VC, Sloan JM, Salant DJ, Coleman DL, Quillen K, Ravid K, Francis JM. Thrombotic Microangiopathy: A Multidisciplinary Team Approach. Am J Kidney Dis. 2017 Nov; 70(5):715-721.View Related Profiles.

Gordon, Craig
Coleman, David
Salant, David
Sloan, J.
Francis, Jean
Quillen, Karen
Ravid, Katya
Chitalia, Vipul

PMID: 28720207.

Abbonante V, Chitalia V, Rosti V, Leiva O, Matsuura S, Balduini A, Ravid K. Upregulation of lysyl oxidase and adhesion to collagen of human megakaryocytes and platelets in primary myelofibrosis. Blood. 2017 08 10; 130(6):829-831.View Related Profiles.

Ravid, Katya
Matsuura, Shinobu
Chitalia, Vipul

PMID: 28592432.

Grenz A, Bauerle JD, Dalton JH, Ridyard D, Badulak A, Tak E, McNamee EN, Clambey E, Moldovan R, Reyes G, Klawitter J, Ambler K, Magee K, Christians U, Brodsky KS, Ravid K, Choi DS, Wen J, Lukashev D, Blackburn MR, Osswald H, Coe IR, Nürnberg B, Haase VH, Xia Y, Sitkovsky M, Eltzschig HK. Equilibrative nucleoside transporter 1 (ENT1) regulates postischemic blood flow during acute kidney injury in mice. J Clin Invest. 2017 06 01; 127(6):2438. PMID: 28569735.

Abbonante V, Di Buduo CA, Gruppi C, De Maria C, Spedden E, De Acutis A, Staii C, Raspanti M, Vozzi G, Kaplan DL, Moccia F, Ravid K, Balduini A. A new path to platelet production through matrix sensing. Haematologica. 2017 Jul; 102(7):1150-1160. PMID: 28411253; DOI: 10.3324/haematol.2016.161562;.

Showing 10 of 146 results. Show More

Leiva O, Ng SK, Chitalia S, Balduini A, Matsuura S, Ravid K. The role of the extracellular matrix in primary myelofibrosis. Blood Cancer J. 2017 Feb 03; 7(2):e525.View Related Profiles.

Ravid, Katya
Matsuura, Shinobu

PMID: 28157219; DOI: 10.1038/bcj.2017.6;.

Lucero HA, Patterson S, Matsuura S, Ravid K. Quantitative histological image analyses of reticulin fibers in a myelofibrotic mouse. J Biol Methods. 2016; 3(4).View Related Profiles.

Ravid, Katya
Patterson, Shenia
Matsuura, Shinobu

PMID: 28008415; DOI: 10.14440/jbm.2016.152;.

Matsuura S, Patterson S, Lucero H, Leiva O, Grant AK, Herrera VL, Ravid K. In vivo magnetic resonance imaging of a mouse model of myelofibrosis. Blood Cancer J. 2016 11 11; 6(11):e497.View Related Profiles.

Ravid, Katya
Patterson, Shenia
Matsuura, Shinobu
Herrera, Victoria

PMID: 27834941; DOI: 10.1038/bcj.2016.97;.

Sun Y, Hu W, Yu X, Liu Z, Tarran R, Ravid K, Huang P. Actinin-1 binds to the C-terminus of A2B adenosine receptor (A2BAR) and enhances A2BAR cell-surface expression. Biochem J. 2016 Jul 15; 473(14):2179-86. PMID: 27208173; DOI: 10.1042/BCJ20160272;.

Matsuura S, Mi R, Koupenova M, Eliades A, Patterson S, Toselli P, Thon J, Italiano JE, Trackman PC, Papadantonakis N, Ravid K. Lysyl oxidase is associated with increased thrombosis and platelet reactivity. Blood. 2016 Mar 17; 127(11):1493-501.View Related Profiles.

Ravid, Katya
Toselli, Paul
Trackman, Philip
Mi, Rongjuan
Matsuura, Shinobu

PMID: 26755713; PMCID: PMC4797025; DOI: 10.1182/blood-2015-02-629667;.

Eisenstein A, Patterson S, Ravid K. The Many Faces of the A2b Adenosine Receptor in Cardiovascular and Metabolic Diseases. J Cell Physiol. 2015 Dec; 230(12):2891-7.View Related Profiles.

Eisenstein, Anna
Ravid, Katya
Patterson, Shenia

PMID: 25975415; DOI: 10.1002/jcp.25043;.

Cohen HB, Ward A, Hamidzadeh K, Ravid K, Mosser DM. IFN-? Prevents Adenosine Receptor (A2bR) Upregulation To Sustain the Macrophage Activation Response. J Immunol. 2015 Oct 15; 195(8):3828-37. PMID: 26355158; PMCID: PMC4686143; DOI: 10.4049/jimmunol.1501139;.

Seo SW, Koeppen M, Bonney S, Gobel M, Thayer M, Harter PN, Ravid K, Eltzschig HK, Mittelbronn M, Walker L, Eckle T. Differential Tissue-Specific Function of Adora2b in Cardioprotection. J Immunol. 2015 Aug 15; 195(4):1732-43. PMID: 26136425; PMCID: PMC4576932; DOI: 10.4049/jimmunol.1402288;.

Jing L, Tamplin OJ, Chen MJ, Deng Q, Patterson S, Kim PG, Durand EM, McNeil A, Green JM, Matsuura S, Ablain J, Brandt MK, Schlaeger TM, Huttenlocher A, Daley GQ, Ravid K, Zon LI. Adenosine signaling promotes hematopoietic stem and progenitor cell emergence. J Exp Med. 2015 May 4; 212(5):649-63.View Related Profiles.

Ravid, Katya
Patterson, Shenia
Matsuura, Shinobu

PMID: 25870200; PMCID: PMC4419349; DOI: 10.1084/jem.20141528;.

Xu YX, Ashline D, Liu L, Tassa C, Shaw SY, Ravid K, Layne MD, Reinhold V, Robbins PW. The glycosylation-dependent interaction of perlecan core protein with LDL: implications for atherosclerosis. J Lipid Res. 2015 Feb; 56(2):266-76.View Related Profiles.

Ravid, Katya
Layne, Matthew
Robbins, Phillips

PMID: 25528754; PMCID: PMC4306681; DOI: 10.1194/jlr.M053017;.

Eisenstein A, Carroll SH, Johnston-Cox H, Farb M, Gokce N, Ravid K. An adenosine receptor-Krüppel-like factor 4 protein axis inhibits adipogenesis. J Biol Chem. 2014 Jul 25; 289(30):21071-81.View Related Profiles.

Johnston-Cox, Hillary
Ravid, Katya
Farb, Melissa
Gokce, Noyan

PMID: 24928509; PMCID: PMC4110311.

Johnston-Cox H, Eisenstein AS, Koupenova M, Carroll S, Ravid K. The macrophage A2B adenosine receptor regulates tissue insulin sensitivity. PLoS One. 2014; 9(6):e98775.View Related Profiles.

Eisenstein, Anna
Johnston-Cox, Hillary
Ravid, Katya

PMID: 24892847; PMCID: PMC4043770; DOI: 10.1371/journal.pone.0098775;.

Grenz A, Bauerle JD, Dalton JH, Ridyard D, Badulak A, Tak E, McNamee EN, Clambey E, Moldovan R, Reyes G, Klawitter J, Ambler K, Magee K, Christians U, Brodsky KS, Ravid K, Choi DS, Wen J, Lukashev D, Blackburn MR, Osswald H, Coe IR, Nürnberg B, Haase VH, Xia Y, Sitkovsky M, Eltzschig HK. Expression of concern. Equilibrative nucleoside transporter 1 (ENT1) regulates postischemic blood flow during acute kidney injury in mice. J Clin Invest. 2014 Jun 2; 124(6):2807. PMID: 24812671; PMCID: PMC4089445; DOI: 10.1172/JCI76888;.

Koupenova M, Vitseva O, MacKay CR, Beaulieu LM, Benjamin EJ, Mick E, Kurt-Jones EA, Ravid K, Freedman JE. Platelet-TLR7 mediates host survival and platelet count during viral infection in the absence of platelet-dependent thrombosis. Blood. 2014 Jul 31; 124(5):791-802.View Related Profiles.

Benjamin, Emelia
Ravid, Katya
Beaulieu, Lea
Koupenova-Zamor, Milka
Vitseva, Olga

PMID: 24755410; PMCID: PMC4118487; DOI: 10.1182/blood-2013-11-536003;.

Eisenstein A, Ravid K. G protein-coupled receptors and adipogenesis: a focus on adenosine receptors. J Cell Physiol. 2014 Apr; 229(4):414-21.View Related Profiles.

Eisenstein, Anna
Ravid, Katya

PMID: 24114647; DOI: 10.1002/jcp.24473;.

Ravid K. New roads to a megakaryocyte inner territory. Blood. 2014 Feb 6; 123(6):803-4. PMID: 24505065; DOI: 10.1182/blood-2013-11-535591;.

Tak E, Ridyard D, Kim JH, Zimmerman M, Werner T, Wang XX, Shabeka U, Seo SW, Christians U, Klawitter J, Moldovan R, Garcia G, Levi M, Haase V, Ravid K, Eltzschig HK, Grenz A. CD73-dependent generation of adenosine and endothelial Adora2b signaling attenuate diabetic nephropathy. J Am Soc Nephrol. 2014 Mar; 25(3):547-63. PMID: 24262796; PMCID: PMC3935577; DOI: 10.1681/ASN.2012101014;.

Cohen HB, Briggs KT, Marino JP, Ravid K, Robson SC, Mosser DM. TLR stimulation initiates a CD39-based autoregulatory mechanism that limits macrophage inflammatory responses. Blood. 2013 Sep 12; 122(11):1935-45. PMID: 23908469; PMCID: PMC3772500; DOI: 10.1182/blood-2013-04-496216;.

Ravid K, Wolozin B. The Scientist's Pledge. Acad Med. 2013 Jun; 88(6):743.View Related Profiles.

Wolozin, Benjamin
Ravid, Katya

PMID: 23708595; DOI: 10.1097/ACM.0b013e31828f9f96;.

Sher N, Von Stetina JR, Bell GW, Matsuura S, Ravid K, Orr-Weaver TL. Fundamental differences in endoreplication in mammals and Drosophila revealed by analysis of endocycling and endomitotic cells. Proc Natl Acad Sci U S A. 2013 Jun 4; 110(23):9368-73.View Related Profiles.

Ravid, Katya
Matsuura, Shinobu

PMID: 23613587; PMCID: PMC3677442; DOI: 10.1073/pnas.1304889110;.

Eckle T, Hughes K, Ehrentraut H, Brodsky KS, Rosenberger P, Choi DS, Ravid K, Weng T, Xia Y, Blackburn MR, Eltzschig HK. Crosstalk between the equilibrative nucleoside transporter ENT2 and alveolar Adora2b adenosine receptors dampens acute lung injury. FASEB J. 2013 Aug; 27(8):3078-89. PMID: 23603835; PMCID: PMC3714574; DOI: 10.1096/fj.13-228551;.

Eliades A, Papadantonakis N, Matsuura S, Mi R, Bais MV, Trackman P, Ravid K. Megakaryocyte polyploidy is inhibited by lysyl oxidase propeptide. Cell Cycle. 2013 Apr 15; 12(8):1242-50.View Related Profiles.

Ravid, Katya
Bais, Manish
Trackman, Philip
Mi, Rongjuan
Matsuura, Shinobu

PMID: 23518500; PMCID: PMC3674089; DOI: 10.4161/cc.24312;.

Koupenova M, Ravid K. Adenosine, adenosine receptors and their role in glucose homeostasis and lipid metabolism. J Cell Physiol. 2013 Mar 04.View Related Profiles.

Ravid, Katya
Koupenova-Zamor, Milka

PMID: 23460239; DOI: 10.1002/jcp.24352;.

Carroll SH, Ravid K. Differentiation of mesenchymal stem cells to osteoblasts and chondrocytes: a focus on adenosine receptors. Expert Rev Mol Med. 2013; 15:e1. PMID: 23406574; DOI: 10.1017/erm.2013.2;.

Ravid K, Faux R, Corkey B, Coleman D. Building interdisciplinary biomedical research using novel collaboratives. Acad Med. 2013 Feb; 88(2):179-84.View Related Profiles.

Coleman, David
Ravid, Katya

PMID: 23269301; DOI: 10.1097/ACM.0b013e31827c0f79;.

Coleman DL, Spira A, Ravid K. Promoting interdisciplinary research in departments of medicine: results from two models at Boston University School of Medicine. Trans Am Clin Climatol Assoc. 2013; 124:275-82.View Related Profiles.

Spira, Avrum
Coleman, David
Ravid, Katya

PMID: 23874035; PMCID: PMC3715902.

Koupenova M, Johnston-Cox H, Ravid K. Regulation of atherosclerosis and associated risk factors by adenosine and adenosine receptors. Curr Atheroscler Rep. 2012 Oct; 14(5):460-8.View Related Profiles.

Johnston-Cox, Hillary
Ravid, Katya
Koupenova-Zamor, Milka

PMID: 22850979; PMCID: PMC3759396; DOI: 10.1007/s11883-012-0263-y;.

Eliades A, Matsuura S, Ravid K. Oxidases and reactive oxygen species during hematopoiesis: a focus on megakaryocytes. J Cell Physiol. 2012 Oct; 227(10):3355-62.View Related Profiles.

Ravid, Katya
Matsuura, Shinobu

PMID: 22331622; PMCID: PMC3357446; DOI: 10.1002/jcp.24071;.

Johnston-Cox H, Koupenova M, Yang D, Corkey B, Gokce N, Farb MG, LeBrasseur N, Ravid K. The A2b adenosine receptor modulates glucose homeostasis and obesity. PLoS One. 2012; 7(7):e40584.View Related Profiles.

Johnston-Cox, Hillary
Ravid, Katya
Farb, Melissa
Koupenova-Zamor, Milka
Gokce, Noyan

PMID: 22848385; PMCID: PMC3405065; DOI: 10.1371/journal.pone.0040584;.

Papadantonakis N, Matsuura S, Ravid K. Megakaryocyte pathology and bone marrow fibrosis: the lysyl oxidase connection. Blood. 2012 Aug 30; 120(9):1774-81.View Related Profiles.

Ravid, Katya
Matsuura, Shinobu

PMID: 22767499; PMCID: PMC3433087; DOI: 10.1182/blood-2012-02-402594;.

Sun Y, Duan Y, Eisenstein AS, Hu W, Quintana A, Lam WK, Wang Y, Wu Z, Ravid K, Huang P. A novel mechanism of control of NF?B activation and inflammation involving A2B adenosine receptors. J Cell Sci. 2012 Oct 1; 125(Pt 19):4507-17.View Related Profiles.

Eisenstein, Anna
Ravid, Katya

PMID: 22767505; PMCID: PMC3500865; DOI: 10.1242/jcs.105023;.

Rudich N, Ravid K, Sagi-Eisenberg R. Mast cell adenosine receptors function: a focus on the a3 adenosine receptor and inflammation. Front Immunol. 2012; 3:134. PMID: 22675325; PMCID: PMC3366457; DOI: 10.3389/fimmu.2012.00134;.

Johnston-Cox HA, Koupenova M, Ravid K. A2 adenosine receptors and vascular pathologies. Arterioscler Thromb Vasc Biol. 2012 Apr; 32(4):870-8.View Related Profiles.

Johnston-Cox, Hillary
Ravid, Katya
Koupenova-Zamor, Milka

PMID: 22423039; DOI: 10.1161/ATVBAHA.112.246181;.

Carroll SH, Wigner NA, Kulkarni N, Johnston-Cox H, Gerstenfeld LC, Ravid K. A2B adenosine receptor promotes mesenchymal stem cell differentiation to osteoblasts and bone formation in vivo. J Biol Chem. 2012 May 4; 287(19):15718-27.View Related Profiles.

Johnston-Cox, Hillary
Ravid, Katya
Gerstenfeld, Louis

PMID: 22403399; PMCID: PMC3346096; DOI: 10.1074/jbc.M112.344994;.

Kataoka S, Baquero A, Yang D, Shultz N, Vandenbeuch A, Ravid K, Kinnamon SC, Finger TE. A2BR adenosine receptor modulates sweet taste in circumvallate taste buds. PLoS One. 2012; 7(1):e30032. PMID: 22253866; PMCID: PMC3254652; DOI: 10.1371/journal.pone.0030032;.

Koupenova M, Johnston-Cox H, Vezeridis A, Gavras H, Yang D, Zannis V, Ravid K. A2b adenosine receptor regulates hyperlipidemia and atherosclerosis. Circulation. 2012 Jan 17; 125(2):354-63.View Related Profiles.

Gavras, Haralambos
Johnston-Cox, Hillary
Ravid, Katya
Koupenova-Zamor, Milka
Zannis, Vassilis

PMID: 22144568; PMCID: PMC3265935; DOI: 10.1161/CIRCULATIONAHA.111.057596;.

van der Hoeven D, Wan TC, Gizewski ET, Kreckler LM, Maas JE, Van Orman J, Ravid K, Auchampach JA. A role for the low-affinity A2B adenosine receptor in regulating superoxide generation by murine neutrophils. J Pharmacol Exp Ther. 2011 Sep; 338(3):1004-12. PMID: 21693629; PMCID: PMC3164346; DOI: 10.1124/jpet.111.181792;.

Eliades A, Papadantonakis N, Bhupatiraju A, Burridge KA, Johnston-Cox HA, Migliaccio AR, Crispino JD, Lucero HA, Trackman PC, Ravid K. Control of megakaryocyte expansion and bone marrow fibrosis by lysyl oxidase. J Biol Chem. 2011 Aug 5; 286(31):27630-8.View Related Profiles.

Bhupatiraju, Ajoy
Johnston-Cox, Hillary
Ravid, Katya
Trackman, Philip

PMID: 21665949; PMCID: PMC3149354; DOI: 10.1074/jbc.M111.243113;.

Chen H, Koupenova M, Yang D, Sume SS, Trackman PC, Ravid K. Regulation of MMP-9 expression by the A2b adenosine receptor and its dependency on TNF-a signaling. Exp Hematol. 2011 May; 39(5):525-30.View Related Profiles.

Ravid, Katya
Koupenova-Zamor, Milka
Trackman, Philip
Sume, Siddika

PMID: 21320567; DOI: 10.1016/j.exphem.2011.02.004;.

Johnston-Cox HA, Ravid K. Adenosine and blood platelets. Purinergic Signal. 2011 Sep; 7(3):357-65.View Related Profiles.

Johnston-Cox, Hillary
Ravid, Katya

PMID: 21484090; PMCID: PMC3166992; DOI: 10.1007/s11302-011-9220-4;.

Figler RA, Wang G, Srinivasan S, Jung DY, Zhang Z, Pankow JS, Ravid K, Fredholm B, Hedrick CC, Rich SS, Kim JK, LaNoue KF, Linden J. Links between insulin resistance, adenosine A2B receptors, and inflammatory markers in mice and humans. Diabetes. 2011 Feb; 60(2):669-79. PMID: 21270276; PMCID: PMC3028369; DOI: 10.2337/db10-1070;.

Johnston-Cox HA, Yang D, Ravid K. Physiological implications of adenosine receptor-mediated platelet aggregation. J Cell Physiol. 2011 Jan; 226(1):46-51.View Related Profiles.

Johnston-Cox, Hillary
Ravid, Katya

PMID: 20717958; DOI: 10.1002/jcp.22379;.

Grimsby JL, Lucero HA, Trackman PC, Ravid K, Kagan HM. Role of lysyl oxidase propeptide in secretion and enzyme activity. J Cell Biochem. 2010 Dec 1; 111(5):1231-43.View Related Profiles.

Kagan, Herbert
Ravid, Katya
Trackman, Philip

PMID: 20717923; DOI: 10.1002/jcb.22845;.

Ravid K. The value of a native milieu: mutated non-muscle myosin IIA does lead to thrombocytopenia. J Thromb Haemost. 2010 Oct; 8(10):2241-2. PMID: 20723023; DOI: 10.1111/j.1538-7836.2010.04027.x;.

McCrann DJ, Ravid K. Survivin localization during endomitosis of high ploidy mouse megakaryocytes. Blood. 2010 Sep 23; 116(12):2192-3. PMID: 20864587; PMCID: PMC2951860; DOI: 10.1182/blood-2010-04-280420;.

Anvari F, Sharma AK, Fernandez LG, Hranjec T, Ravid K, Kron IL, Laubach VE. Tissue-derived proinflammatory effect of adenosine A2B receptor in lung ischemia-reperfusion injury. J Thorac Cardiovasc Surg. 2010 Oct; 140(4):871-7. PMID: 20659747; PMCID: PMC2943004; DOI: 10.1016/j.jtcvs.2010.06.051;.

Eliades A, Papadantonakis N, Ravid K. New roles for cyclin E in megakaryocytic polyploidization. J Biol Chem. 2010 Jun 11; 285(24):18909-17. PMID: 20392692; PMCID: PMC2881813; DOI: 10.1074/jbc.M110.102145;.

Yang D, Chen H, Koupenova M, Carroll SH, Eliades A, Freedman JE, Toselli P, Ravid K. A new role for the A2b adenosine receptor in regulating platelet function. J Thromb Haemost. 2010 Apr; 8(4):817-27.View Related Profiles.

Freedman, Jane
Ravid, Katya
Koupenova-Zamor, Milka
Toselli, Paul

PMID: 20102488; DOI: 10.1111/j.1538-7836.2010.03769.x;.

Nguyen HG, Ravid K. Polyploidy: mechanisms and cancer promotion in hematopoietic and other cells. Adv Exp Med Biol. 2010; 676:105-22.View Related Profiles.

Nguyen, Hao
Ravid, Katya

PMID: 20687472.

Genzen JR, Yang D, Ravid K, Bordey A. Activation of adenosine A2B receptors enhances ciliary beat frequency in mouse lateral ventricle ependymal cells. Cerebrospinal Fluid Res. 2009; 6:15. PMID: 19922651; PMCID: PMC2791093; DOI: 10.1186/1743-8454-6-15;.

Ravid K. MAL: not just a leukemia inducer. Blood. 2009 Nov 5; 114(19):3977-8. PMID: 19892723; DOI: 10.1182/blood-2009-09-242818;.

Ravid K. Megakaryocytes survive without survivin. Blood. 2009 Jul 2; 114(1):4. PMID: 19574480; DOI: 10.1182/blood-2009-04-216713;.

McCrann DJ, Eliades A, Makitalo M, Matsuno K, Ravid K. Differential expression of NADPH oxidases in megakaryocytes and their role in polyploidy. Blood. 2009 Aug 6; 114(6):1243-9. PMID: 19471020; PMCID: PMC2723018; DOI: 10.1182/blood-2008-12-195883;.

Chen H, Yang D, Carroll SH, Eltzschig HK, Ravid K. Activation of the macrophage A2b adenosine receptor regulates tumor necrosis factor-alpha levels following vascular injury. Exp Hematol. 2009 May; 37(5):533-8. PMID: 19375644; DOI: 10.1016/j.exphem.2009.02.001;.

Chandrasekharan BP, Kolachala VL, Dalmasso G, Merlin D, Ravid K, Sitaraman SV, Srinivasan S. Adenosine 2B receptors (A(2B)AR) on enteric neurons regulate murine distal colonic motility. FASEB J. 2009 Aug; 23(8):2727-34. PMID: 19357134; PMCID: PMC2717778; DOI: 10.1096/fj.09-129544;.

Nguyen HG, Makitalo M, Yang D, Chinnappan D, St Hilaire C, Ravid K. Deregulated Aurora-B induced tetraploidy promotes tumorigenesis. FASEB J. 2009 Aug; 23(8):2741-8.View Related Profiles.

Nguyen, Hao
Ravid, Katya

PMID: 19332642; PMCID: PMC2717782; DOI: 10.1096/fj.09-130963;.

McCrann DJ, Yang D, Chen H, Carroll S, Ravid K. Upregulation of Nox4 in the aging vasculature and its association with smooth muscle cell polyploidy. Cell Cycle. 2009 Mar 15; 8(6):902-8. PMID: 19221493; PMCID: PMC2744814.

St Hilaire C, Carroll SH, Chen H, Ravid K. Mechanisms of induction of adenosine receptor genes and its functional significance. J Cell Physiol. 2009 Jan; 218(1):35-44. PMID: 18767039; PMCID: PMC3265330; DOI: 10.1002/jcp.21579;.

Kintsurashvili E, Shenouda S, Ona D, Ona L, Ahmad S, Ravid K, Gavras I, Gavras H. Hypertension in transgenic mice with brain-selective overexpression of the alpha(2B)-adrenoceptor. Am J Hypertens. 2009 Jan; 22(1):41-5.View Related Profiles.

Gavras, Haralambos
Gavras, Irene
Ravid, Katya

PMID: 18989257; DOI: 10.1038/ajh.2008.314;.

Liu L, Brown D, McKee M, Lebrasseur NK, Yang D, Albrecht KH, Ravid K, Pilch PF. Deletion of Cavin/PTRF causes global loss of caveolae, dyslipidemia, and glucose intolerance. Cell Metab. 2008 Oct; 8(4):310-7.View Related Profiles.

Ravid, Katya
Albrecht, Kenneth
Liu, Libin
Pilch, Paul

PMID: 18840361; PMCID: PMC2581738; DOI: 10.1016/j.cmet.2008.07.008;.

St Hilaire C, Koupenova M, Carroll SH, Smith BD, Ravid K. TNF-alpha upregulates the A2B adenosine receptor gene: The role of NAD(P)H oxidase 4. Biochem Biophys Res Commun. 2008 Oct 24; 375(3):292-6.View Related Profiles.

Smith, Barbara
Ravid, Katya
Koupenova-Zamor, Milka

PMID: 18647598; PMCID: PMC2583397; DOI: 10.1016/j.bbrc.2008.07.059;.

Lucero HA, Ravid K, Grimsby JL, Rich CB, DiCamillo SJ, Mäki JM, Myllyharju J, Kagan HM. Lysyl oxidase oxidizes cell membrane proteins and enhances the chemotactic response of vascular smooth muscle cells. J Biol Chem. 2008 Aug 29; 283(35):24103-17.View Related Profiles.

Kagan, Herbert
Ravid, Katya

PMID: 18586678; PMCID: PMC2527118; DOI: 10.1074/jbc.M709897200;.

Grenz A, Osswald H, Eckle T, Yang D, Zhang H, Tran ZV, Klingel K, Ravid K, Eltzschig HK. The reno-vascular A2B adenosine receptor protects the kidney from ischemia. PLoS Med. 2008 Jun 24; 5(6):e137. PMID: 18578565; PMCID: PMC2504049; DOI: 10.1371/journal.pmed.0050137;.

McCrann DJ, Nguyen HG, Jones MR, Ravid K. Vascular smooth muscle cell polyploidy: an adaptive or maladaptive response? J Cell Physiol. 2008 Jun; 215(3):588-92.View Related Profiles.

Nguyen, Hao
Ravid, Katya
Jones, Matthew

PMID: 18181174; DOI: 10.1002/jcp.21363;.

Kolachala VL, Vijay-Kumar M, Dalmasso G, Yang D, Linden J, Wang L, Gewirtz A, Ravid K, Merlin D, Sitaraman SV. A2B adenosine receptor gene deletion attenuates murine colitis. Gastroenterology. 2008 Sep; 135(3):861-70. PMID: 18601927; PMCID: PMC2632861; DOI: 10.1053/j.gastro.2008.05.049;.

Papadantonakis N, Makitalo M, McCrann DJ, Liu K, Nguyen HG, Martin G, Patel-Hett S, Italiano JE, Ravid K. Direct visualization of the endomitotic cell cycle in living megakaryocytes: differential patterns in low and high ploidy cells. Cell Cycle. 2008 Aug; 7(15):2352-6.View Related Profiles.

Nguyen, Hao
Ravid, Katya

PMID: 18677109; PMCID: PMC2861775.

Ravid K. Platelet marginal bands: not so marginal. Blood. 2008 May 1; 111(9):4423. PMID: 18441237; DOI: 10.1182/blood-2008-02-137786;.

St Hilaire C, Yang D, Schreiber BM, Ravid K. B-Myb regulates the A(2B) adenosine receptor in vascular smooth muscle cells. J Cell Biochem. 2008 Apr 15; 103(6):1962-74.View Related Profiles.

Schreiber, Barbara
Ravid, Katya

PMID: 17979185; PMCID: PMC3303598.

Xu Y, Ravid K, Smith BD. Major histocompatibility class II transactivator expression in smooth muscle cells from A2b adenosine receptor knock-out mice: cross-talk between the adenosine and interferon-gamma signaling. J Biol Chem. 2008 May 23; 283(21):14213-20.View Related Profiles.

Smith, Barbara
Ravid, Katya

PMID: 18359773; PMCID: PMC2386913; DOI: 10.1074/jbc.M708657200;.

McCrann DJ, Yezefski T, Nguyen HG, Papadantonakis N, Liu H, Wen Q, Crispino JD, Ravid K. Survivin overexpression alone does not alter megakaryocyte ploidy nor interfere with erythroid/megakaryocytic lineage development in transgenic mice. Blood. 2008 Apr 15; 111(8):4092-5.View Related Profiles.

Nguyen, Hao
Ravid, Katya

PMID: 18245663; PMCID: PMC2288720; DOI: 10.1182/blood-2007-11-122150;.

Yang D, Koupenova M, McCrann DJ, Kopeikina KJ, Kagan HM, Schreiber BM, Ravid K. The A2b adenosine receptor protects against vascular injury. Proc Natl Acad Sci U S A. 2008 Jan 15; 105(2):792-6.View Related Profiles.

Schreiber, Barbara
Kagan, Herbert
Ravid, Katya
Koupenova-Zamor, Milka

PMID: 18184815; PMCID: PMC2206615; DOI: 10.1073/pnas.0705563105;.

Hurtado PA, Vora S, Sume SS, Yang D, St Hilaire C, Guo Y, Palamakumbura AH, Schreiber BM, Ravid K, Trackman PC. Lysyl oxidase propeptide inhibits smooth muscle cell signaling and proliferation. Biochem Biophys Res Commun. 2008 Feb 1; 366(1):156-61.View Related Profiles.

Schreiber, Barbara
Ravid, Katya
Trackman, Philip
Sume, Siddika

PMID: 18060869; PMCID: PMC2211633.

Yang D, McCrann DJ, Nguyen H, St Hilaire C, DePinho RA, Jones MR, Ravid K. Increased polyploidy in aortic vascular smooth muscle cells during aging is marked by cellular senescence. Aging Cell. 2007 Apr; 6(2):257-60.View Related Profiles.

Nguyen, Hao
Ravid, Katya
Jones, Matthew

PMID: 17291294; PMCID: PMC3303600.

Faenza I, Ramazzotti G, Bavelloni A, Fiume R, Gaboardi GC, Follo MY, Gilmour RS, Martelli AM, Ravid K, Cocco L. Inositide-dependent phospholipase C signaling mimics insulin in skeletal muscle differentiation by affecting specific regions of the cyclin D3 promoter. Endocrinology. 2007 Mar; 148(3):1108-17. PMID: 17122077.

Hazony Y, Lu J, St Hilaire C, Ravid K. Hematopoietic gene promoters subjected to a group-combinatorial study of DNA samples: identification of a megakaryocytic selective DNA signature. Nucleic Acids Res. 2006; 34(16):4416-28. PMID: 16936310; PMCID: PMC1636359.

Nguyen HG, Ravid K. Tetraploidy/aneuploidy and stem cells in cancer promotion: The role of chromosome passenger proteins. J Cell Physiol. 2006 Jul; 208(1):12-22.View Related Profiles.

Nguyen, Hao
Ravid, Katya

PMID: 16331679.

Yang D, Zhang Y, Nguyen HG, Koupenova M, Chauhan AK, Makitalo M, Jones MR, St Hilaire C, Seldin DC, Toselli P, Lamperti E, Schreiber BM, Gavras H, Wagner DD, Ravid K. The A2B adenosine receptor protects against inflammation and excessive vascular adhesion. J Clin Invest. 2006 Jul; 116(7):1913-23.View Related Profiles.

Schreiber, Barbara
Seldin, David
Nguyen, Hao
Gavras, Haralambos
Ravid, Katya
Jones, Matthew
Koupenova-Zamor, Milka
Toselli, Paul

PMID: 16823489; PMCID: PMC1483170.

Nguyen HG, Chinnappan D, Urano T, Ravid K. Mechanism of Aurora-B degradation and its dependency on intact KEN and A-boxes: identification of an aneuploidy-promoting property. Mol Cell Biol. 2005 Jun; 25(12):4977-92.View Related Profiles.

Nguyen, Hao
Ravid, Katya

PMID: 15923616; PMCID: PMC1140599.

Nguyen HG, Yu G, Makitalo M, Yang D, Xie HX, Jones MR, Ravid K. Conditional overexpression of transgenes in megakaryocytes and platelets in vivo. Blood. 2005 Sep 1; 106(5):1559-64.View Related Profiles.

Nguyen, Hao
Ravid, Katya
Jones, Matthew

PMID: 15890684; PMCID: PMC1895218.

Nagata Y, Jones MR, Nguyen HG, McCrann DJ, St Hilaire C, Schreiber BM, Hashimoto A, Inagaki M, Earnshaw WC, Todokoro K, Ravid K. Vascular smooth muscle cell polyploidization involves changes in chromosome passenger proteins and an endomitotic cell cycle. Exp Cell Res. 2005 May 1; 305(2):277-91.View Related Profiles.

Schreiber, Barbara
Nguyen, Hao
Ravid, Katya
Jones, Matthew

PMID: 15817153.

Yaar R, Jones MR, Chen JF, Ravid K. Animal models for the study of adenosine receptor function. J Cell Physiol. 2005 Jan; 202(1):9-20.View Related Profiles.

Ravid, Katya
Jones, Matthew

PMID: 15389588.

Jones MR, Zhao Z, Sullivan CP, Schreiber BM, Stone PJ, Toselli PA, Kagan HM, Cohen RA, Ravid K. A(3) adenosine receptor deficiency does not influence atherogenesis. J Cell Biochem. 2004 Aug 1; 92(5):1034-43.View Related Profiles.

Schreiber, Barbara
Kagan, Herbert
Ravid, Katya
Jones, Matthew
Toselli, Paul
Stone, Phillip
Cohen, Richard

PMID: 15258925.

Zhang Y, Nagata Y, Yu G, Nguyen HG, Jones MR, Toselli P, Jackson CW, Tatsuka M, Todokoro K, Ravid K. Aberrant quantity and localization of Aurora-B/AIM-1 and survivin during megakaryocyte polyploidization and the consequences of Aurora-B/AIM-1-deregulated expression. Blood. 2004 May 15; 103(10):3717-26.View Related Profiles.

Nguyen, Hao
Ravid, Katya
Jones, Matthew
Toselli, Paul

PMID: 14751927.

Bernardin-Fried F, Kummalue T, Leijen S, Collector MI, Ravid K, Friedman AD. AML1/RUNX1 increases during G1 to S cell cycle progression independent of cytokine-dependent phosphorylation and induces cyclin D3 gene expression. J Biol Chem. 2004 Apr 9; 279(15):15678-87. PMID: 14747476.

Kaluzhny Y, Ravid K. Role of apoptotic processes in platelet biogenesis. Acta Haematol. 2004; 111(1-2):67-77. PMID: 14646346.

Lu J, Pazin MJ, Ravid K. Properties of ets-1 binding to chromatin and its effect on platelet factor 4 gene expression. Mol Cell Biol. 2004 Jan; 24(1):428-41. PMID: 14673175; PMCID: PMC303331.

Jones MR, Ravid K. Vascular smooth muscle polyploidization as a biomarker for aging and its impact on differential gene expression. J Biol Chem. 2004 Feb 13; 279(7):5306-13.View Related Profiles.

Ravid, Katya
Jones, Matthew

PMID: 14634004.

Lu J, Pierron A, Ravid K. An adenosine analogue, IB-MECA, down-regulates estrogen receptor alpha and suppresses human breast cancer cell proliferation. Cancer Res. 2003 Oct 1; 63(19):6413-23. PMID: 14559831.

Hechler B, Zhang Y, Eckly A, Cazenave JP, Gachet C, Ravid K. Lineage-specific overexpression of the P2Y1 receptor induces platelet hyper-reactivity in transgenic mice. J Thromb Haemost. 2003 Jan; 1(1):155-63. PMID: 12871553.

Yaar R, Lamperti ED, Toselli PA, Ravid K. Activity of the A3 adenosine receptor gene promoter in transgenic mice: characterization of previously unidentified sites of expression. FEBS Lett. 2002 Dec 18; 532(3):267-72.View Related Profiles.

Ravid, Katya
Toselli, Paul

PMID: 12482577.

Yaar R, Cataldo LM, Tzatsos A, Francis CE, Zhao Z, Ravid K. Regulation of the A3 adenosine receptor gene in vascular smooth muscle cells: role of a cAMP and GATA element. Mol Pharmacol. 2002 Nov; 62(5):1167-76. PMID: 12391281.

Kaluzhny Y, Hechler B, Lu J, Nguyen HG, Cataldo LM, Ravid K. A selective effect of Mpl ligand on mRNA stabilization during megakaryocyte differentiation. FEBS Lett. 2002 Sep 11; 527(1-3):279-83.View Related Profiles.

Nguyen, Hao
Ravid, Katya

PMID: 12220674.

Kaluzhny Y, Yu G, Sun S, Toselli PA, Nieswandt B, Jackson CW, Ravid K. BclxL overexpression in megakaryocytes leads to impaired platelet fragmentation. Blood. 2002 Sep 1; 100(5):1670-8.View Related Profiles.

Ravid, Katya
Toselli, Paul

PMID: 12176887.

Chinnappan D, Zhang Y, Ravid K. AIM-1 transgenic mice with a curly tail phenotype and its chromosome location. Cytogenet Genome Res. 2002; 98(2-3):231A. PMID: 12698010.

Zhang Y, Sun S, Wang Z, Thompson A, Kaluzhny Y, Zimmet J, Ravid K. Signaling by the Mpl receptor involves IKK and NF-kappaB. J Cell Biochem. 2002; 85(3):523-35. PMID: 11967992.

Zhao Z, Yaar R, Ladd D, Cataldo LM, Ravid K. Overexpression of A3 adenosine receptors in smooth, cardiac, and skeletal muscle is lethal to embryos. Microvasc Res. 2002 Jan; 63(1):61-9. PMID: 11749073.

Ravid K, Lu J, Zimmet JM, Jones MR. Roads to polyploidy: the megakaryocyte example. J Cell Physiol. 2002 Jan; 190(1):7-20.View Related Profiles.

Ravid, Katya
Jones, Matthew

PMID: 11807806.

Hechler B, Toselli P, Ravanat C, Gachet C, Ravid K. Mpl ligand increases P2Y1 receptor gene expression in megakaryocytes with no concomitant change in platelet response to ADP. Mol Pharmacol. 2001 Nov; 60(5):1112-20.View Related Profiles.

Ravid, Katya
Toselli, Paul

PMID: 11641440.

Zhang Y, Sun S, Chen WC, Kaluzhny Y, Chinnappan D, Yu G, Ravid K. Repression of AIM-1 kinase mRNA as part of a program of genes regulated by Mpl ligand. Biochem Biophys Res Commun. 2001 Apr 6; 282(3):844-9. PMID: 11401541.

Sun S, Zimmet JM, Toselli P, Thompson A, Jackson CW, Ravid K. Overexpression of cyclin D1 moderately increases ploidy in megakaryocytes. Haematologica. 2001 Jan; 86(1):17-23.View Related Profiles.

Ravid, Katya
Toselli, Paul

PMID: 11146565.

Zhao Z, Makaritsis K, Francis CE, Gavras H, Ravid K. A role for the A3 adenosine receptor in determining tissue levels of cAMP and blood pressure: studies in knock-out mice. Biochim Biophys Acta. 2000 Mar 17; 1500(3):280-90.View Related Profiles.

Gavras, Haralambos
Ravid, Katya

PMID: 10699369.

Sun S, Jackson CW, Ravid K. MAP kinase localizes to the platelet-yielding demarcation membrane system in megakaryocytes. Blood. 2000 Feb 15; 95(4):1511. PMID: 10722281.

Zimmet J, Ravid K. Polyploidy: occurrence in nature, mechanisms, and significance for the megakaryocyte-platelet system. Exp Hematol. 2000 Jan; 28(1):3-16. PMID: 10658672.

Sun S, Ravid K. Role of a serine/threonine kinase, Mst1, in megakaryocyte differentiation. J Cell Biochem. 1999 Nov; 76(1):44-60. PMID: 10581000.

Ravid K, Smith-Mungo LI, Zhao Z, Thomas KM, Kagan HM. Upregulation of lysyl oxidase in vascular smooth muscle cells by cAMP: role for adenosine receptor activation. J Cell Biochem. 1999 Oct 1; 75(1):177-85.View Related Profiles.

Kagan, Herbert
Ravid, Katya

PMID: 10462716.

Thompson A, Ravid K. Repression of A TAF(II)32 isoform as part of a program of genes regulated during mpl ligand-induced megakaryocyte differentiation. Biochem Biophys Res Commun. 1999 Aug 19; 262(1):55-9. PMID: 10448067.

Wang Z, Zhang Y, Lu J, Sun S, Ravid K. Mpl ligand enhances the transcription of the cyclin D3 gene: a potential role for Sp1 transcription factor. Blood. 1999 Jun 15; 93(12):4208-21. PMID: 10361118.

Zhao Z, Francis C, Ravid K. Characterization of the mouse A3 adenosine receptor gene: exon/intron organization and promoter activity. Genomics. 1999 Apr 1; 57(1):152-5. PMID: 10191095.

Sun S, Kaluzhny Y, Ravid K. Ectopic expression of the Aspergillus nidulans mitotic inducer, nimA kinase, in megakaryocytes: effect on polyploidization. Exp Hematol. 1999 Apr; 27(4):594-604. PMID: 10210317.

Cataldo LM, Zhang Y, Lu J, Ravid K. Rat NAP1: cDNA cloning and upregulation by Mpl ligand. Gene. 1999 Jan 21; 226(2):355-64. PMID: 9931510.

Zhang Y, Wang Z, Liu DX, Pagano M, Ravid K. Ubiquitin-dependent degradation of cyclin B is accelerated in polyploid megakaryocytes. J Biol Chem. 1998 Jan 16; 273(3):1387-92. PMID: 9430673.

Zimmet JM, Toselli P, Ravid K. Cyclin D3 and megakaryocyte development: exploration of a transgenic phenotype. Stem Cells. 1998; 16 Suppl 2:97-106.View Related Profiles.

Ravid, Katya
Toselli, Paul

PMID: 11012182.

Zimmet JM, Ladd D, Jackson CW, Stenberg PE, Ravid K. A role for cyclin D3 in the endomitotic cell cycle. Mol Cell Biol. 1997 Dec; 17(12):7248-59. PMID: 9372957; PMCID: PMC232582.

Zhao Z, Francis CE, Welch G, Loscalzo J, Ravid K. Reduced glutathione prevents nitric oxide-induced apoptosis in vascular smooth muscle cells. Biochim Biophys Acta. 1997 Nov 27; 1359(2):143-52. PMID: 9409811.

Zhao Z, Francis CE, Ravid K. An A3-subtype adenosine receptor is highly expressed in rat vascular smooth muscle cells: its role in attenuating adenosine-induced increase in cAMP. Microvasc Res. 1997 Nov; 54(3):243-52. PMID: 9441895.

Thompson A, Zhang Y, Kamen D, Jackson CW, Cardiff RD, Ravid K. Deregulated expression of c-myc in megakaryocytes of transgenic mice increases megakaryopoiesis and decreases polyploidization. J Biol Chem. 1996 Sep 20; 271(38):22976-82. PMID: 8798484.

Wang Z, Sicinski P, Weinberg RA, Zhang Y, Ravid K. Characterization of the mouse cyclin D3 gene: exon/intron organization and promoter activity. Genomics. 1996 Jul 1; 35(1):156-63. PMID: 8661116.

Zhang Y, Wang Z, Ravid K. The cell cycle in polyploid megakaryocytes is associated with reduced activity of cyclin B1-dependent cdc2 kinase. J Biol Chem. 1996 Feb 23; 271(8):4266-72. PMID: 8626773.

Thompson A, Zhao Z, Ladd D, Zimmet J, Ravid K. A new transgenic mouse model for the study of cell cycle control in megakaryocytes. Stem Cells. 1996; 14 Suppl 1:181-7. PMID: 11012219.

Wang Z, Zhang Y, Kamen D, Lees E, Ravid K. Cyclin D3 is essential for megakaryocytopoiesis. Blood. 1995 Nov 15; 86(10):3783-8. PMID: 7579345.

Zhao Z, Ravid S, Ravid K. Chromosomal mapping of the mouse A3 adenosine receptor gene, Adora3. Genomics. 1995 Nov 1; 30(1):118-9. PMID: 8595892.

Ravid K, Kuter DJ, Rosenberg RD. rmIL-6 stimulates the transcriptional activity of the rat PF4 gene. Exp Hematol. 1995 May; 23(5):397-401. PMID: 7720812.

Block KL, Ravid K, Phung QH, Poncz M. Characterization of regulatory elements in the 5'-flanking region of the rat GPIIb gene by studies in a primary rat marrow culture system. Blood. 1994 Nov 15; 84(10):3385-93. PMID: 7949093.

Ravid K, Li YC, Rayburn HB, Rosenberg RD. Targeted expression of a conditional oncogene in hematopoietic cells of transgenic mice. J Cell Biol. 1993 Dec; 123(6 Pt 1):1545-53. PMID: 8253849; PMCID: PMC2290873.

Ravid K, Kuter DJ, Beeler DL, Doi T, Rosenberg RD. Selection of an HEL-derived cell line expressing high levels of platelet factor 4. Blood. 1993 Jun 1; 81(11):2885-90. PMID: 8499627.

Grabarek J, Raychowdhury M, Ravid K, Kent KC, Newman PJ, Ware JA. Identification and functional characterization of protein kinase C isozymes in platelets and HEL cells. J Biol Chem. 1992 May 15; 267(14):10011-7. PMID: 1374394.

Ravid K, Doi T, Beeler DL, Kuter DJ, Rosenberg RD. Transcriptional regulation of the rat platelet factor 4 gene: interaction between an enhancer/silencer domain and the GATA site. Mol Cell Biol. 1991 Dec; 11(12):6116-27. PMID: 1944279; PMCID: PMC361789.

Ravid K, Beeler DL, Rabin MS, Ruley HE, Rosenberg RD. Selective targeting of gene products with the megakaryocyte platelet factor 4 promoter. Proc Natl Acad Sci U S A. 1991 Feb 15; 88(4):1521-5. PMID: 1899930; PMCID: PMC51051.

Ravid K, Rosenthal RA, Doctrow SR, Lowenstein JM. 28 kDa adenosine-binding proteins of brain and other tissues. Biochem J. 1989 Mar 15; 258(3):653-61.View Related Profiles.

Ravid, Katya
Doctrow, Susan

PMID: 2730563; PMCID: PMC1138416.

Ravid K, Lowenstein JM. Changes in adenosine receptors during differentiation of 3T3-F442A cells to adipocytes. Biochem J. 1988 Jan 15; 249(2):377-81. PMID: 2829856; PMCID: PMC1148714.

Ravid K, Diamant P, Avi-Dor Y. Interrelation between salvage of purine nucleotides and protein synthesis in rat heart cells. Arch Biochem Biophys. 1985 Jan; 236(1):159-66. PMID: 3966790.

Ravid K, Diamant P, Avi-Dor Y. Regulation of the salvage pathway of purine nucleotide synthesis by the oxidation state of NAD+ in rat heart cells. Arch Biochem Biophys. 1984 Mar; 229(2):632-9. PMID: 6200076.

Ravid K, Lavie L, Gershon D. The presence of NADPH-glyceraldehyde 3-phosphate oxidoreductase in macrophages. FEBS Lett. 1983 Oct 3; 162(1):107-11. PMID: 6617882.

Ravid K, Avi-Dor Y. Spectrophotometric determination of cyanide based on the formation of NAD+-cyanide addition compound. Anal Biochem. 1980 Nov 1; 108(2):343-5. PMID: 7457878.

Ravid K, Diamant P, Avi-Dor Y. Glucose-dependent stimulation of protein synthesis in cultured heart muscle cells. Possible involvement of the pentose phosphate pathway. FEBS Lett. 1980 Sep 22; 119(1):20-4. PMID: 6775978.

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 146 publications over 34 distinct years, with a maximum of 13 publications in 2008

Bar chart showing 146 publications over 34 distinct years, with a maximum of 13 publications in 2008

Year	Publications
1980	2
1983	1
1984	1
1985	1
1988	1
1989	1
1991	2
1992	1
1993	2
1994	1
1995	3
1996	4
1997	3
1998	2
1999	7
2000	3
2001	3
2002	8
2003	3
2004	5
2005	4
2006	4
2007	2
2008	13
2009	9
2010	7
2011	7
2012	10
2013	10
2014	7
2015	4
2016	4
2017	8
2018	3

In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Adenosine Receptors
Blood Cells
Cell Cycle Control
Hematopoietic Stem Cells
Megakaryocyte
Platelet
Polyploidy
Vascular Biology

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