Platelet activation plays a central role in thrombosis and hemostasis, while these processes are central to vascular health and disease. In the platelet lineage, bone marrow stem cells develop into early committed megakaryocyte progenitors, which undergo a unique cell cycle leading to polyploid cells prior to fragmenting into platelets. Our research focuses on mechanisms that regulate these processes under normal conditions vs. pathology. We proposed a new paradigm for controlling the transcription of genes uniquely expressed in this lineage, by identifying a cluster of non-tissue specific transcription factors that, together, constitute a signature uniquely driving this lineage development, among other cell lineages in the bone marrow. Studies were extended to identifying mechanisms governing polyploidy in megakaryocytes, leading also to better understanding of regulatory processes that cause polyploidy in other cells, such as aging vascular smooth muscle cells. Past projects involved molecular characterization of platelet and vascular adenosine receptors, and exploration of their roles in such cellular function. Importantly, knowledge gained by studying basic regulatory processes in healthy megakaryocytes and platelets aids our investigation of bone marrow pathologies, such as myeloproliferative neoplasms (MPNs). The systems used include primary bone marrow cultures, as well as transgenic and knock out mouse models.
Diversity, Equity, Inclusion and Accessibility
Commitment to inclusion, justice and excellence has been at the core of my professional and personal life. Diversity has been shown in various forums to contribute to creativity, mutual enrichment and collaborative building. Over the years, I have taken steps to contribute to enhanced diversity in our academic community in several ways, such as: 1. In the context of directly promoting interdisciplinary research related to health equity, I am currently (2022) the Director of a newly funded American Heart Association Center focused on the study of “Cancer-Associated Thromboembolism as Affected by Health Disparities (CAT-HD)”; 2. Affinity Research Collaborative groups within the Evans Center for Interdisciplinary Biomedical Research, which I direct, work on engaging patients and community members from underserved populations; 3. I participate as Subject Matter Expert on "Expanding Interdisciplinary Research" at the Northeast Faculty Leadership Program: Faculty Success through Diversity (NFLP), a leadership program for senior faculty of color funded by the Alfred P. Sloan Foundation, including tenured, underrepresented STEM faculty from ten area universities: Boston University, Harvard University, Northeastern University, Salem State University, Suffolk University, Tufts University, University of Connecticut, University of Massachusetts Boston, Wellesley College, and Wheaton College (Principal Investigator: Debra L. Franko, Ph.D., Northeastern University); 4. In my own laboratory, and through my leadership roles, I have served as a mentor to pre- and post-doctoral fellows and junior faculty of minority populations, who continue to propel the messages of research excellence and inclusion; 5. Within the Cardiovascular Biology NIH-funded training program that I directed for nearly 2 decades at BUSM, I made sure to provide opportunities to students of minority populations, with 20% of our trainees self-identifying as Hispanic or Black, and 50% as females; 6. As past member of admissions committees at BUSM, I participated in granting full attention to evaluating trainees from underserved communities; 7. The problems of inequity and bias can often be gender-based. Through my leadership roles, I have encouraged women researchers (trainees and faculty) to believe and achieve. Most of my past mentees are holding faculty and research leadership positions, nationwide and internationally.
Professor
Boston University Chobanian & Avedisian School of Medicine
Biochemistry
Member
Boston University
BU-BMC Cancer Center
Member
Boston University
Whitaker Cardiovascular Institute
Founding Director
Boston University
Evans Center for Interdisciplinary Biomedical Research
Director, Master of Science Program in Biomedical Research
Boston University Chobanian & Avedisian School of Medicine
Medicine
Member
Boston University
Genome Science Institute
Graduate Faculty (Primary Mentor of Grad Students)
Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences
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- Data is sorted by project end date, and updated monthly.
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- Grant title
- Project period and this person’s role on the grant
- PI name, if this person is not the PI (the name will link if PI has a BU Profile)
- Funding source(s). An arrow indicates the flow of funding if multiple sponsors.
- Some grants will show an agency award/project number, and may be a link.
- Data is sorted by project end date, and updated monthly.
This tab shows grant data from the Boston VA. We are only showing grant title, and only for people in the role of PI.
Lysyl Oxidase Pharmacological Inhibition of Bone Marow Fibrosis03/01/2016 - 12/31/2025 (PI)
Pharmaxis
Allostatic Load and Cardio-Oncology Disparities10/01/2022 - 09/30/2025 (PI)
American Heart Association
Megakaryocyte Mechanosensing Toward Platelet Biogenesis09/01/2021 - 07/31/2025 (PI)
NIH/National Heart, Lung, and Blood Institute5R01HL158670-02
Cancer-Associated Thromboembolism as Affected by Health Disparities (CAT-HD)07/01/2021 - 06/30/2025 (PI)
American Heart Association
A path to thrombosis in primary myelofibrosis12/24/2017 - 11/30/2022 (PI)
NIH/National Heart, Lung, and Blood Institute5R01HL136363-04
Training Program in Cardiovascular Biology: Pre-Doctoral12/01/2014 - 11/30/2020 (PI)
NIH/National Heart, Lung, and Blood Institute5T32HL007969-15
Mechanism of Bone Marrow Neoplasm-Induced Osteosclerosis05/01/2018 - 04/30/2020 (Multi-PI)
PI:
Katya Ravid, DScNIH/National Institute of Arthritis & Musculoskeletal & Skin Diseases5R21AR072748-02
Mechanisms of Control of Lysyl Oxidase Expression in JAK2-Mutated Myelofibrotic Cells07/01/2017 - 06/30/2018 (Key Person / Mentor)
American Society of Hematology
Mechanisms Regulating Megakaryocyte Development04/01/2012 - 09/30/2017 (PI)
NIH/National Heart, Lung, and Blood Institute5R01HL080442-09
The role of lysysl oxidase in facilitating JAK2V617F mutation-induced myelofibrosis07/01/2016 - 06/30/2017 (Key Person / Mentor)
American Society of Hematology
Showing 10 of 19 results.
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Nanoplatforms for Imaging Bone Marrow Fibrosis10/01/2014 - 09/30/2016 (PI)
MPN Research Foundation
Mechanisms Regulating Megakaryocte Development04/01/2012 - 03/31/2016 (PI)
NIH/National Heart, Lung, and Blood Institute2R01HL080442-06A1
Training in Cardiovascular Biology: Predoctoral07/01/2001 - 11/30/2014 (PI)
NIH/National Heart, Lung, and Blood Institute5T32HL007969-10
Training in Cardiovascular Biology: Predoctoral07/01/2011 - 06/30/2014 (PI)
NIH/National Heart, Lung, and Blood Institute5T32HL007969-09
Adenosine Receptors and Atherogenesis04/01/2009 - 03/31/2014 (PI)
NIH/National Heart, Lung, and Blood Institute5R01HL093149-04
The A2b Adenosine Receptor as Regulator of Type II Diabetes09/30/1997 - 03/31/2013 (Subcontract PI)
Boston Medical Center Corporation NIH NIDDK5P30DK046200-20
Properties of Polypoloid Cells in a Model of Aging06/01/2003 - 05/31/2005 (PI)
NIH/National Institute on Aging1 R03 AG22623 01
Mechanisms Regulating Endomitosis in Megakaryocytes08/01/1997 - 07/31/2004 (PI)
NIH/National Heart, Lung, and Blood Institute5 R01 HL58547 05
Targeting Gene Products to Megakaryocytes/Platelets in Transgenic Mice07/01/1995 - 06/30/2000 (PI)
American Heart Association
Showing 10 of 61 results.
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Publications listed below are automatically derived from MEDLINE/PubMed and other
sources, which might result in incorrect or missing publications. Faculty can
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to make corrections and additions.
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Leiva O, Hobbs G, Ravid K, Libby P. Cardiovascular Disease in Myeloproliferative Neoplasms: JACC: CardioOncology State-of-the-Art Review. JACC CardioOncol. 2022 Jun; 4(2):166-182. PMID: 35818539; PMCID: PMC9270630; DOI: 10.1016/j.jaccao.2022.04.002;
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Karagianni A, Ravid K. Myeloproliferative disorders and their effects on bone homeostasis: the role of megakaryocytes. Blood. 2022 May 26; 139(21):3127-3137. PMID: 34428274; PMCID: PMC9136883; DOI: 10.1182/blood.2021011480;
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Gaye MM, Ward CM, Piasecki AJ, Stahl VL, Karagianni A, Costello CE, Ravid K. Characterization of Glycoproteoforms of Integrins a2 and ß1 in Megakaryocytes in the Occurrence of JAK2V617F Mutation-Induced Primary Myelofibrosis. Mol Cell Proteomics. 2022 Apr; 21(4):100213.View Related Profiles. PMID: 35182768; PMCID: PMC8968581; DOI: 10.1016/j.mcpro.2022.100213;
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Walker JA, Richards S, Whelan SA, Yoo SB, Russell TL, Arinze N, Lotfollahzadeh S, Napoleon MA, Belghasem M, Lee N, Dember LM, Ravid K, Chitalia VC. Indoleamine 2,3-dioxygenase-1, a Novel Therapeutic Target for Post-Vascular Injury Thrombosis in CKD. J Am Soc Nephrol. 2021 11; 32(11):2834-2850.View Related Profiles. PMID: 34716244; PMCID: PMC8806102; DOI: 10.1681/ASN.2020091310;
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Piasecki A, Leiva O, Ravid K. Lysyl oxidase inhibition in primary myelofibrosis: A renewed strategy. Arch Stem Cell Ther. 2020 Dec; 1(1):23-27. PMID: 33738462; PMCID: PMC7968867; DOI: 10.46439/stemcell.1.005;
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Eisenstein A, Chitalia SV, Ravid K. Bone Marrow and Adipose Tissue Adenosine Receptors Effect on Osteogenesis and Adipogenesis. Int J Mol Sci. 2020 Oct 10; 21(20). PMID: 33050467; PMCID: PMC7589187; DOI: 10.3390/ijms21207470;
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Matsuura S, Thompson CR, Belghasem ME, Bekendam RH, Piasecki A, Leiva O, Ray A, Italiano J, Yang M, Merill-Skoloff G, Chitalia VC, Flaumenhaft R, Ravid K. Platelet Dysfunction and Thrombosis in JAK2V617F-Mutated Primary Myelofibrotic Mice. Arterioscler Thromb Vasc Biol. 2020 10; 40(10):e262-e272.View Related Profiles. PMID: 32814440; PMCID: PMC7605151; DOI: 10.1161/ATVBAHA.120.314760;
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Matsuura S, Thompson CR, Ng SK, Ward CM, Karagianni A, Mazzeo C, Malara A, Balduini A, Ravid K. Adhesion to fibronectin via a5ß1 integrin supports expansion of the megakaryocyte lineage in primary myelofibrosis. Blood. 2020 06 18; 135(25):2286-2291.View Related Profiles. PMID: 32294178; PMCID: PMC7316217; DOI: 10.1182/blood.2019004230;
Showing 10 of 164 results.
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Belghasem M, Roth D, Richards S, Napolene MA, Walker J, Yin W, Arinze N, Lyle C, Spencer C, Francis JM, Thompson C, Andry C, Whelan SA, Lee N, Ravid K, Chitalia VC. Metabolites in a mouse cancer model enhance venous thrombogenicity through the aryl hydrocarbon receptor-tissue factor axis. Blood. 2019 12 26; 134(26):2399-2413.View Related Profiles. PMID: 31877217; PMCID: PMC6933294; DOI: 10.1182/blood.2019001675;
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Walker JA, Richards S, Belghasem ME, Arinze N, Yoo SB, Tashjian JY, Whelan SA, Lee N, Kolachalama VB, Francis J, Ravid K, Sherr D, Chitalia VC. Temporal and tissue-specific activation of aryl hydrocarbon receptor in discrete mouse models of kidney disease. Kidney Int. 2020 03; 97(3):538-550.View Related Profiles. PMID: 31932072
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Sano S, Wang Y, Yura Y, Sano M, Oshima K, Yang Y, Katanasaka Y, Min KD, Matsuura S, Ravid K, Mohi G, Walsh K. JAK2V617F -Mediated Clonal Hematopoiesis Accelerates Pathological Remodeling in Murine Heart Failure. JACC Basic Transl Sci. 2019 Oct; 4(6):684-697.View Related Profiles. PMID: 31709318; PMCID: PMC6834960; DOI: 10.1016/j.jacbts.2019.05.013;
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Li HM, Jang JH, Jung JS, Shin J, Park CO, Kim YJ, Ahn WG, Nam JS, Hong CW, Lee J, Jung YJ, Chen JF, Ravid K, Lee HT, Huh WK, Kabarowski JH, Song DK. G2A Protects Mice against Sepsis by Modulating Kupffer Cell Activation: Cooperativity with Adenosine Receptor 2b. J Immunol. 2019 01 15; 202(2):527-538. PMID: 30530591; PMCID: PMC6477683; DOI: 10.4049/jimmunol.1700783;
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Artuz CM, Knights AJ, Funnell APW, Gonda TJ, Ravid K, Pearson RCM, Quinlan KGR, Crossley M. Partial reprogramming of heterologous cells by defined factors to generate megakaryocyte lineage-restricted biomolecules. Biotechnol Rep (Amst). 2018 Dec; 20:e00285. PMID: 30364711; PMCID: PMC6197760; DOI: 10.1016/j.btre.2018.e00285;
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Kolachalama VB, Shashar M, Alousi F, Shivanna S, Rijal K, Belghasem ME, Walker J, Matsuura S, Chang GH, Gibson CM, Dember LM, Francis JM, Ravid K, Chitalia VC. Uremic Solute-Aryl Hydrocarbon Receptor-Tissue Factor Axis Associates with Thrombosis after Vascular Injury in Humans. J Am Soc Nephrol. 2018 03; 29(3):1063-1072.View Related Profiles. PMID: 29343519; PMCID: PMC5827608; DOI: 10.1681/ASN.2017080929;
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Leiva O, Leon C, Kah Ng S, Mangin P, Gachet C, Ravid K. The role of extracellular matrix stiffness in megakaryocyte and platelet development and function. Am J Hematol. 2018 03; 93(3):430-441. PMID: 29247535; PMCID: PMC5803306; DOI: 10.1002/ajh.25008;
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Shashar M, Belghasem ME, Matsuura S, Walker J, Richards S, Alousi F, Rijal K, Kolachalama VB, Balcells M, Odagi M, Nagasawa K, Henderson JM, Gautam A, Rushmore R, Francis J, Kirchhofer D, Kolandaivelu K, Sherr DH, Edelman ER, Ravid K, Chitalia VC. Targeting STUB1-tissue factor axis normalizes hyperthrombotic uremic phenotype without increasing bleeding risk. Sci Transl Med. 2017 Nov 22; 9(417).View Related Profiles. PMID: 29167396; PMCID: PMC5854487; DOI: 10.1126/scitranslmed.aam8475;
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Ravid K, Seta F, Center D, Waters G, Coleman D. Catalyzing Interdisciplinary Research and Training: Initial Outcomes and Evolution of the Affinity Research Collaboratives Model. Acad Med. 2017 Oct; 92(10):1399-1405.View Related Profiles. PMID: 28445220
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Gordon CE, Chitalia VC, Sloan JM, Salant DJ, Coleman DL, Quillen K, Ravid K, Francis JM. Thrombotic Microangiopathy: A Multidisciplinary Team Approach. Am J Kidney Dis. 2017 Nov; 70(5):715-721.View Related Profiles. PMID: 28720207
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Grenz A, Bauerle JD, Dalton JH, Ridyard D, Badulak A, Tak E, McNamee EN, Clambey E, Moldovan R, Reyes G, Klawitter J, Ambler K, Magee K, Christians U, Brodsky KS, Ravid K, Choi DS, Wen J, Lukashev D, Blackburn MR, Osswald H, Coe IR, Nürnberg B, Haase VH, Xia Y, Sitkovsky M, Eltzschig HK. Equilibrative nucleoside transporter 1 (ENT1) regulates postischemic blood flow during acute kidney injury in mice. J Clin Invest. 2017 06 01; 127(6):2438. PMID: 28569735; PMCID: PMC5451218; DOI: 10.1172/JCI94890;
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Abbonante V, Di Buduo CA, Gruppi C, De Maria C, Spedden E, De Acutis A, Staii C, Raspanti M, Vozzi G, Kaplan DL, Moccia F, Ravid K, Balduini A. A new path to platelet production through matrix sensing. Haematologica. 2017 Jul; 102(7):1150-1160. PMID: 28411253; PMCID: PMC5566016; DOI: 10.3324/haematol.2016.161562;
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Sun Y, Hu W, Yu X, Liu Z, Tarran R, Ravid K, Huang P. Actinin-1 binds to the C-terminus of A2B adenosine receptor (A2BAR) and enhances A2BAR cell-surface expression. Biochem J. 2016 Jul 15; 473(14):2179-86. PMID: 27208173; DOI: 10.1042/BCJ20160272;
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Matsuura S, Mi R, Koupenova M, Eliades A, Patterson S, Toselli P, Thon J, Italiano JE, Trackman PC, Papadantonakis N, Ravid K. Lysyl oxidase is associated with increased thrombosis and platelet reactivity. Blood. 2016 Mar 17; 127(11):1493-501.View Related Profiles. PMID: 26755713; PMCID: PMC4797025; DOI: 10.1182/blood-2015-02-629667;
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Cohen HB, Ward A, Hamidzadeh K, Ravid K, Mosser DM. IFN-? Prevents Adenosine Receptor (A2bR) Upregulation To Sustain the Macrophage Activation Response. J Immunol. 2015 Oct 15; 195(8):3828-37. PMID: 26355158; PMCID: PMC4686143; DOI: 10.4049/jimmunol.1501139;
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Seo SW, Koeppen M, Bonney S, Gobel M, Thayer M, Harter PN, Ravid K, Eltzschig HK, Mittelbronn M, Walker L, Eckle T. Differential Tissue-Specific Function of Adora2b in Cardioprotection. J Immunol. 2015 Aug 15; 195(4):1732-43. PMID: 26136425; PMCID: PMC4576932; DOI: 10.4049/jimmunol.1402288;
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Jing L, Tamplin OJ, Chen MJ, Deng Q, Patterson S, Kim PG, Durand EM, McNeil A, Green JM, Matsuura S, Ablain J, Brandt MK, Schlaeger TM, Huttenlocher A, Daley GQ, Ravid K, Zon LI. Adenosine signaling promotes hematopoietic stem and progenitor cell emergence. J Exp Med. 2015 May 4; 212(5):649-63.View Related Profiles. PMID: 25870200; PMCID: PMC4419349; DOI: 10.1084/jem.20141528;
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Xu YX, Ashline D, Liu L, Tassa C, Shaw SY, Ravid K, Layne MD, Reinhold V, Robbins PW. The glycosylation-dependent interaction of perlecan core protein with LDL: implications for atherosclerosis. J Lipid Res. 2015 Feb; 56(2):266-76.View Related Profiles. PMID: 25528754; PMCID: PMC4306681; DOI: 10.1194/jlr.M053017;
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Grenz A, Bauerle JD, Dalton JH, Ridyard D, Badulak A, Tak E, McNamee EN, Clambey E, Moldovan R, Reyes G, Klawitter J, Ambler K, Magee K, Christians U, Brodsky KS, Ravid K, Choi DS, Wen J, Lukashev D, Blackburn MR, Osswald H, Coe IR, Nürnberg B, Haase VH, Xia Y, Sitkovsky M, Eltzschig HK. Expression of concern. Equilibrative nucleoside transporter 1 (ENT1) regulates postischemic blood flow during acute kidney injury in mice. J Clin Invest. 2014 Jun 2; 124(6):2807. PMID: 24812671; PMCID: PMC4089445; DOI: 10.1172/JCI76888;
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Koupenova M, Vitseva O, MacKay CR, Beaulieu LM, Benjamin EJ, Mick E, Kurt-Jones EA, Ravid K, Freedman JE. Platelet-TLR7 mediates host survival and platelet count during viral infection in the absence of platelet-dependent thrombosis. Blood. 2014 Jul 31; 124(5):791-802.View Related Profiles. PMID: 24755410; PMCID: PMC4118487; DOI: 10.1182/blood-2013-11-536003;
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Tak E, Ridyard D, Kim JH, Zimmerman M, Werner T, Wang XX, Shabeka U, Seo SW, Christians U, Klawitter J, Moldovan R, Garcia G, Levi M, Haase V, Ravid K, Eltzschig HK, Grenz A. CD73-dependent generation of adenosine and endothelial Adora2b signaling attenuate diabetic nephropathy. J Am Soc Nephrol. 2014 Mar; 25(3):547-63. PMID: 24262796; PMCID: PMC3935577; DOI: 10.1681/ASN.2012101014;
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Cohen HB, Briggs KT, Marino JP, Ravid K, Robson SC, Mosser DM. TLR stimulation initiates a CD39-based autoregulatory mechanism that limits macrophage inflammatory responses. Blood. 2013 Sep 12; 122(11):1935-45. PMID: 23908469; PMCID: PMC3772500; DOI: 10.1182/blood-2013-04-496216;
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Sher N, Von Stetina JR, Bell GW, Matsuura S, Ravid K, Orr-Weaver TL. Fundamental differences in endoreplication in mammals and Drosophila revealed by analysis of endocycling and endomitotic cells. Proc Natl Acad Sci U S A. 2013 Jun 4; 110(23):9368-73.View Related Profiles. PMID: 23613587; PMCID: PMC3677442; DOI: 10.1073/pnas.1304889110;
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Eckle T, Hughes K, Ehrentraut H, Brodsky KS, Rosenberger P, Choi DS, Ravid K, Weng T, Xia Y, Blackburn MR, Eltzschig HK. Crosstalk between the equilibrative nucleoside transporter ENT2 and alveolar Adora2b adenosine receptors dampens acute lung injury. FASEB J. 2013 Aug; 27(8):3078-89. PMID: 23603835; PMCID: PMC3714574; DOI: 10.1096/fj.13-228551;
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Carroll SH, Ravid K. Differentiation of mesenchymal stem cells to osteoblasts and chondrocytes: a focus on adenosine receptors. Expert Rev Mol Med. 2013; 15:e1. PMID: 23406574; DOI: 10.1017/erm.2013.2;
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Coleman DL, Spira A, Ravid K. Promoting interdisciplinary research in departments of medicine: results from two models at Boston University School of Medicine. Trans Am Clin Climatol Assoc. 2013; 124:275-82.View Related Profiles. PMID: 23874035; PMCID: PMC3715902
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Sun Y, Duan Y, Eisenstein AS, Hu W, Quintana A, Lam WK, Wang Y, Wu Z, Ravid K, Huang P. A novel mechanism of control of NF?B activation and inflammation involving A2B adenosine receptors. J Cell Sci. 2012 Oct 1; 125(Pt 19):4507-17.View Related Profiles. PMID: 22767505; PMCID: PMC3500865; DOI: 10.1242/jcs.105023;
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Rudich N, Ravid K, Sagi-Eisenberg R. Mast cell adenosine receptors function: a focus on the a3 adenosine receptor and inflammation. Front Immunol. 2012; 3:134. PMID: 22675325; PMCID: PMC3366457; DOI: 10.3389/fimmu.2012.00134;
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Carroll SH, Wigner NA, Kulkarni N, Johnston-Cox H, Gerstenfeld LC, Ravid K. A2B adenosine receptor promotes mesenchymal stem cell differentiation to osteoblasts and bone formation in vivo. J Biol Chem. 2012 May 4; 287(19):15718-27.View Related Profiles. PMID: 22403399; PMCID: PMC3346096; DOI: 10.1074/jbc.M112.344994;
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Grenz A, Bauerle JD, Dalton JH, Ridyard D, Badulak A, Tak E, McNamee EN, Clambey E, Moldovan R, Reyes G, Klawitter J, Ambler K, Magee K, Christians U, Brodsky KS, Ravid K, Choi DS, Wen J, Lukashev D, Blackburn MR, Osswald H, Coe IR, Nürnberg B, Haase VH, Xia Y, Sitkovsky M, Eltzschig HK. Equilibrative nucleoside transporter 1 (ENT1) regulates postischemic blood flow during acute kidney injury in mice. J Clin Invest. 2012 Feb 1; 122(2):693-710. PMID: 22269324; PMCID: PMC3266792; DOI: 10.1172/JCI60214;
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Kataoka S, Baquero A, Yang D, Shultz N, Vandenbeuch A, Ravid K, Kinnamon SC, Finger TE. A2BR adenosine receptor modulates sweet taste in circumvallate taste buds. PLoS One. 2012; 7(1):e30032. PMID: 22253866; PMCID: PMC3254652; DOI: 10.1371/journal.pone.0030032;
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van der Hoeven D, Wan TC, Gizewski ET, Kreckler LM, Maas JE, Van Orman J, Ravid K, Auchampach JA. A role for the low-affinity A2B adenosine receptor in regulating superoxide generation by murine neutrophils. J Pharmacol Exp Ther. 2011 Sep; 338(3):1004-12. PMID: 21693629; PMCID: PMC3164346; DOI: 10.1124/jpet.111.181792;
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Eliades A, Papadantonakis N, Bhupatiraju A, Burridge KA, Johnston-Cox HA, Migliaccio AR, Crispino JD, Lucero HA, Trackman PC, Ravid K. Control of megakaryocyte expansion and bone marrow fibrosis by lysyl oxidase. J Biol Chem. 2011 Aug 5; 286(31):27630-8.View Related Profiles. PMID: 21665949; PMCID: PMC3149354; DOI: 10.1074/jbc.M111.243113;
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Figler RA, Wang G, Srinivasan S, Jung DY, Zhang Z, Pankow JS, Ravid K, Fredholm B, Hedrick CC, Rich SS, Kim JK, LaNoue KF, Linden J. Links between insulin resistance, adenosine A2B receptors, and inflammatory markers in mice and humans. Diabetes. 2011 Feb; 60(2):669-79. PMID: 21270276; PMCID: PMC3028369; DOI: 10.2337/db10-1070;
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Anvari F, Sharma AK, Fernandez LG, Hranjec T, Ravid K, Kron IL, Laubach VE. Tissue-derived proinflammatory effect of adenosine A2B receptor in lung ischemia-reperfusion injury. J Thorac Cardiovasc Surg. 2010 Oct; 140(4):871-7. PMID: 20659747; PMCID: PMC2943004; DOI: 10.1016/j.jtcvs.2010.06.051;
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Eliades A, Papadantonakis N, Ravid K. New roles for cyclin E in megakaryocytic polyploidization. J Biol Chem. 2010 Jun 11; 285(24):18909-17. PMID: 20392692; PMCID: PMC2881813; DOI: 10.1074/jbc.M110.102145;
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Nguyen HG, Ravid K. Polyploidy: mechanisms and cancer promotion in hematopoietic and other cells. Adv Exp Med Biol. 2010; 676:105-22.View Related Profiles. PMID: 20687472
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Genzen JR, Yang D, Ravid K, Bordey A. Activation of adenosine A2B receptors enhances ciliary beat frequency in mouse lateral ventricle ependymal cells. Cerebrospinal Fluid Res. 2009; 6:15. PMID: 19922651; PMCID: PMC2791093; DOI: 10.1186/1743-8454-6-15;
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McCrann DJ, Eliades A, Makitalo M, Matsuno K, Ravid K. Differential expression of NADPH oxidases in megakaryocytes and their role in polyploidy. Blood. 2009 Aug 6; 114(6):1243-9. PMID: 19471020; PMCID: PMC2723018; DOI: 10.1182/blood-2008-12-195883;
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Chen H, Yang D, Carroll SH, Eltzschig HK, Ravid K. Activation of the macrophage A2b adenosine receptor regulates tumor necrosis factor-alpha levels following vascular injury. Exp Hematol. 2009 May; 37(5):533-8. PMID: 19375644; PMCID: PMC5748295; DOI: 10.1016/j.exphem.2009.02.001;
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Chandrasekharan BP, Kolachala VL, Dalmasso G, Merlin D, Ravid K, Sitaraman SV, Srinivasan S. Adenosine 2B receptors (A(2B)AR) on enteric neurons regulate murine distal colonic motility. FASEB J. 2009 Aug; 23(8):2727-34. PMID: 19357134; PMCID: PMC2717778; DOI: 10.1096/fj.09-129544;
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McCrann DJ, Yang D, Chen H, Carroll S, Ravid K. Upregulation of Nox4 in the aging vasculature and its association with smooth muscle cell polyploidy. Cell Cycle. 2009 Mar 15; 8(6):902-8. PMID: 19221493; PMCID: PMC2744814; DOI: 10.4161/cc.8.6.7900;
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St Hilaire C, Carroll SH, Chen H, Ravid K. Mechanisms of induction of adenosine receptor genes and its functional significance. J Cell Physiol. 2009 Jan; 218(1):35-44. PMID: 18767039; PMCID: PMC3265330; DOI: 10.1002/jcp.21579;
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Kintsurashvili E, Shenouda S, Ona D, Ona L, Ahmad S, Ravid K, Gavras I, Gavras H. Hypertension in transgenic mice with brain-selective overexpression of the alpha(2B)-adrenoceptor. Am J Hypertens. 2009 Jan; 22(1):41-5.View Related Profiles. PMID: 18989257; DOI: 10.1038/ajh.2008.314;
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Lucero HA, Ravid K, Grimsby JL, Rich CB, DiCamillo SJ, Mäki JM, Myllyharju J, Kagan HM. Lysyl oxidase oxidizes cell membrane proteins and enhances the chemotactic response of vascular smooth muscle cells. J Biol Chem. 2008 Aug 29; 283(35):24103-17.View Related Profiles. PMID: 18586678; PMCID: PMC2527118; DOI: 10.1074/jbc.M709897200;
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Grenz A, Osswald H, Eckle T, Yang D, Zhang H, Tran ZV, Klingel K, Ravid K, Eltzschig HK. The reno-vascular A2B adenosine receptor protects the kidney from ischemia. PLoS Med. 2008 Jun 24; 5(6):e137. PMID: 18578565; PMCID: PMC2504049; DOI: 10.1371/journal.pmed.0050137;
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Papadantonakis N, Makitalo M, McCrann DJ, Liu K, Nguyen HG, Martin G, Patel-Hett S, Italiano JE, Ravid K. Direct visualization of the endomitotic cell cycle in living megakaryocytes: differential patterns in low and high ploidy cells. Cell Cycle. 2008 Aug; 7(15):2352-6.View Related Profiles. PMID: 18677109; PMCID: PMC2861775; DOI: 10.4161/cc.6325;
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Kolachala VL, Vijay-Kumar M, Dalmasso G, Yang D, Linden J, Wang L, Gewirtz A, Ravid K, Merlin D, Sitaraman SV. A2B adenosine receptor gene deletion attenuates murine colitis. Gastroenterology. 2008 Sep; 135(3):861-70. PMID: 18601927; PMCID: PMC2632861; DOI: 10.1053/j.gastro.2008.05.049;
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Xu Y, Ravid K, Smith BD. Major histocompatibility class II transactivator expression in smooth muscle cells from A2b adenosine receptor knock-out mice: cross-talk between the adenosine and interferon-gamma signaling. J Biol Chem. 2008 May 23; 283(21):14213-20.View Related Profiles. PMID: 18359773; PMCID: PMC2386913; DOI: 10.1074/jbc.M708657200;
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McCrann DJ, Yezefski T, Nguyen HG, Papadantonakis N, Liu H, Wen Q, Crispino JD, Ravid K. Survivin overexpression alone does not alter megakaryocyte ploidy nor interfere with erythroid/megakaryocytic lineage development in transgenic mice. Blood. 2008 Apr 15; 111(8):4092-5.View Related Profiles. PMID: 18245663; PMCID: PMC2288720; DOI: 10.1182/blood-2007-11-122150;
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Hurtado PA, Vora S, Sume SS, Yang D, St Hilaire C, Guo Y, Palamakumbura AH, Schreiber BM, Ravid K, Trackman PC. Lysyl oxidase propeptide inhibits smooth muscle cell signaling and proliferation. Biochem Biophys Res Commun. 2008 Feb 1; 366(1):156-61.View Related Profiles. PMID: 18060869; PMCID: PMC2211633; DOI: 10.1016/j.bbrc.2007.11.116;
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Faenza I, Ramazzotti G, Bavelloni A, Fiume R, Gaboardi GC, Follo MY, Gilmour RS, Martelli AM, Ravid K, Cocco L. Inositide-dependent phospholipase C signaling mimics insulin in skeletal muscle differentiation by affecting specific regions of the cyclin D3 promoter. Endocrinology. 2007 Mar; 148(3):1108-17. PMID: 17122077
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Hazony Y, Lu J, St Hilaire C, Ravid K. Hematopoietic gene promoters subjected to a group-combinatorial study of DNA samples: identification of a megakaryocytic selective DNA signature. Nucleic Acids Res. 2006; 34(16):4416-28. PMID: 16936310; PMCID: PMC1636359; DOI: 10.1093/nar/gkl578;
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Yang D, Zhang Y, Nguyen HG, Koupenova M, Chauhan AK, Makitalo M, Jones MR, St Hilaire C, Seldin DC, Toselli P, Lamperti E, Schreiber BM, Gavras H, Wagner DD, Ravid K. The A2B adenosine receptor protects against inflammation and excessive vascular adhesion. J Clin Invest. 2006 Jul; 116(7):1913-23.View Related Profiles. PMID: 16823489; PMCID: PMC1483170; DOI: 10.1172/JCI27933;
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Nguyen HG, Ravid K. Tetraploidy/aneuploidy and stem cells in cancer promotion: The role of chromosome passenger proteins. J Cell Physiol. 2006 Jul; 208(1):12-22.View Related Profiles. PMID: 16331679
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Nagata Y, Jones MR, Nguyen HG, McCrann DJ, St Hilaire C, Schreiber BM, Hashimoto A, Inagaki M, Earnshaw WC, Todokoro K, Ravid K. Vascular smooth muscle cell polyploidization involves changes in chromosome passenger proteins and an endomitotic cell cycle. Exp Cell Res. 2005 May 1; 305(2):277-91.View Related Profiles. PMID: 15817153
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Yaar R, Jones MR, Chen JF, Ravid K. Animal models for the study of adenosine receptor function. J Cell Physiol. 2005 Jan; 202(1):9-20.View Related Profiles. PMID: 15389588
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Jones MR, Zhao Z, Sullivan CP, Schreiber BM, Stone PJ, Toselli PA, Kagan HM, Cohen RA, Ravid K. A(3) adenosine receptor deficiency does not influence atherogenesis. J Cell Biochem. 2004 Aug 1; 92(5):1034-43.View Related Profiles. PMID: 15258925
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Zhang Y, Nagata Y, Yu G, Nguyen HG, Jones MR, Toselli P, Jackson CW, Tatsuka M, Todokoro K, Ravid K. Aberrant quantity and localization of Aurora-B/AIM-1 and survivin during megakaryocyte polyploidization and the consequences of Aurora-B/AIM-1-deregulated expression. Blood. 2004 May 15; 103(10):3717-26.View Related Profiles. PMID: 14751927
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Bernardin-Fried F, Kummalue T, Leijen S, Collector MI, Ravid K, Friedman AD. AML1/RUNX1 increases during G1 to S cell cycle progression independent of cytokine-dependent phosphorylation and induces cyclin D3 gene expression. J Biol Chem. 2004 Apr 9; 279(15):15678-87. PMID: 14747476
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Kaluzhny Y, Ravid K. Role of apoptotic processes in platelet biogenesis. Acta Haematol. 2004; 111(1-2):67-77. PMID: 14646346
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Lu J, Pazin MJ, Ravid K. Properties of ets-1 binding to chromatin and its effect on platelet factor 4 gene expression. Mol Cell Biol. 2004 Jan; 24(1):428-41. PMID: 14673175; PMCID: PMC303331
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Jones MR, Ravid K. Vascular smooth muscle polyploidization as a biomarker for aging and its impact on differential gene expression. J Biol Chem. 2004 Feb 13; 279(7):5306-13.View Related Profiles. PMID: 14634004
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Lu J, Pierron A, Ravid K. An adenosine analogue, IB-MECA, down-regulates estrogen receptor alpha and suppresses human breast cancer cell proliferation. Cancer Res. 2003 Oct 1; 63(19):6413-23. PMID: 14559831
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Hechler B, Zhang Y, Eckly A, Cazenave JP, Gachet C, Ravid K. Lineage-specific overexpression of the P2Y1 receptor induces platelet hyper-reactivity in transgenic mice. J Thromb Haemost. 2003 Jan; 1(1):155-63. PMID: 12871553
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Yaar R, Lamperti ED, Toselli PA, Ravid K. Activity of the A3 adenosine receptor gene promoter in transgenic mice: characterization of previously unidentified sites of expression. FEBS Lett. 2002 Dec 18; 532(3):267-72.View Related Profiles. PMID: 12482577
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Yaar R, Cataldo LM, Tzatsos A, Francis CE, Zhao Z, Ravid K. Regulation of the A3 adenosine receptor gene in vascular smooth muscle cells: role of a cAMP and GATA element. Mol Pharmacol. 2002 Nov; 62(5):1167-76. PMID: 12391281
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Kaluzhny Y, Hechler B, Lu J, Nguyen HG, Cataldo LM, Ravid K. A selective effect of Mpl ligand on mRNA stabilization during megakaryocyte differentiation. FEBS Lett. 2002 Sep 11; 527(1-3):279-83.View Related Profiles. PMID: 12220674
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Kaluzhny Y, Yu G, Sun S, Toselli PA, Nieswandt B, Jackson CW, Ravid K. BclxL overexpression in megakaryocytes leads to impaired platelet fragmentation. Blood. 2002 Sep 1; 100(5):1670-8.View Related Profiles. PMID: 12176887
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Ravid K, Lu J, Zimmet JM, Jones MR. Roads to polyploidy: the megakaryocyte example. J Cell Physiol. 2002 Jan; 190(1):7-20.View Related Profiles. PMID: 11807806
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Zhao Z, Yaar R, Ladd D, Cataldo LM, Ravid K. Overexpression of A3 adenosine receptors in smooth, cardiac, and skeletal muscle is lethal to embryos. Microvasc Res. 2002 Jan; 63(1):61-9. PMID: 11749073
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Chinnappan D, Zhang Y, Ravid K. AIM-1 transgenic mice with a curly tail phenotype and its chromosome location. Cytogenet Genome Res. 2002; 98(2-3):231A. PMID: 12698010
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Zhang Y, Sun S, Wang Z, Thompson A, Kaluzhny Y, Zimmet J, Ravid K. Signaling by the Mpl receptor involves IKK and NF-kappaB. J Cell Biochem. 2002; 85(3):523-35. PMID: 11967992
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Hechler B, Toselli P, Ravanat C, Gachet C, Ravid K. Mpl ligand increases P2Y1 receptor gene expression in megakaryocytes with no concomitant change in platelet response to ADP. Mol Pharmacol. 2001 Nov; 60(5):1112-20.View Related Profiles. PMID: 11641440
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Zhang Y, Sun S, Chen WC, Kaluzhny Y, Chinnappan D, Yu G, Ravid K. Repression of AIM-1 kinase mRNA as part of a program of genes regulated by Mpl ligand. Biochem Biophys Res Commun. 2001 Apr 6; 282(3):844-9. PMID: 11401541
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Sun S, Zimmet JM, Toselli P, Thompson A, Jackson CW, Ravid K. Overexpression of cyclin D1 moderately increases ploidy in megakaryocytes. Haematologica. 2001 Jan; 86(1):17-23.View Related Profiles. PMID: 11146565
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Zhao Z, Makaritsis K, Francis CE, Gavras H, Ravid K. A role for the A3 adenosine receptor in determining tissue levels of cAMP and blood pressure: studies in knock-out mice. Biochim Biophys Acta. 2000 Mar 17; 1500(3):280-90.View Related Profiles. PMID: 10699369
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Sun S, Jackson CW, Ravid K. MAP kinase localizes to the platelet-yielding demarcation membrane system in megakaryocytes. Blood. 2000 Feb 15; 95(4):1511. PMID: 10722281
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Zimmet J, Ravid K. Polyploidy: occurrence in nature, mechanisms, and significance for the megakaryocyte-platelet system. Exp Hematol. 2000 Jan; 28(1):3-16. PMID: 10658672
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Sun S, Ravid K. Role of a serine/threonine kinase, Mst1, in megakaryocyte differentiation. J Cell Biochem. 1999 Nov; 76(1):44-60. PMID: 10581000
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Ravid K, Smith-Mungo LI, Zhao Z, Thomas KM, Kagan HM. Upregulation of lysyl oxidase in vascular smooth muscle cells by cAMP: role for adenosine receptor activation. J Cell Biochem. 1999 Oct 1; 75(1):177-85.View Related Profiles. PMID: 10462716
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Thompson A, Ravid K. Repression of A TAF(II)32 isoform as part of a program of genes regulated during mpl ligand-induced megakaryocyte differentiation. Biochem Biophys Res Commun. 1999 Aug 19; 262(1):55-9. PMID: 10448067
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Wang Z, Zhang Y, Lu J, Sun S, Ravid K. Mpl ligand enhances the transcription of the cyclin D3 gene: a potential role for Sp1 transcription factor. Blood. 1999 Jun 15; 93(12):4208-21. PMID: 10361118
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Zhao Z, Francis C, Ravid K. Characterization of the mouse A3 adenosine receptor gene: exon/intron organization and promoter activity. Genomics. 1999 Apr 1; 57(1):152-5. PMID: 10191095
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Sun S, Kaluzhny Y, Ravid K. Ectopic expression of the Aspergillus nidulans mitotic inducer, nimA kinase, in megakaryocytes: effect on polyploidization. Exp Hematol. 1999 Apr; 27(4):594-604. PMID: 10210317
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Cataldo LM, Zhang Y, Lu J, Ravid K. Rat NAP1: cDNA cloning and upregulation by Mpl ligand. Gene. 1999 Jan 21; 226(2):355-64. PMID: 9931510
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Zhang Y, Wang Z, Liu DX, Pagano M, Ravid K. Ubiquitin-dependent degradation of cyclin B is accelerated in polyploid megakaryocytes. J Biol Chem. 1998 Jan 16; 273(3):1387-92. PMID: 9430673
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Zimmet JM, Toselli P, Ravid K. Cyclin D3 and megakaryocyte development: exploration of a transgenic phenotype. Stem Cells. 1998; 16 Suppl 2:97-106.View Related Profiles. PMID: 11012182
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Zimmet JM, Ladd D, Jackson CW, Stenberg PE, Ravid K. A role for cyclin D3 in the endomitotic cell cycle. Mol Cell Biol. 1997 Dec; 17(12):7248-59. PMID: 9372957; PMCID: PMC232582
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Zhao Z, Francis CE, Welch G, Loscalzo J, Ravid K. Reduced glutathione prevents nitric oxide-induced apoptosis in vascular smooth muscle cells. Biochim Biophys Acta. 1997 Nov 27; 1359(2):143-52. PMID: 9409811
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Zhao Z, Francis CE, Ravid K. An A3-subtype adenosine receptor is highly expressed in rat vascular smooth muscle cells: its role in attenuating adenosine-induced increase in cAMP. Microvasc Res. 1997 Nov; 54(3):243-52. PMID: 9441895
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Thompson A, Zhang Y, Kamen D, Jackson CW, Cardiff RD, Ravid K. Deregulated expression of c-myc in megakaryocytes of transgenic mice increases megakaryopoiesis and decreases polyploidization. J Biol Chem. 1996 Sep 20; 271(38):22976-82. PMID: 8798484
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Wang Z, Sicinski P, Weinberg RA, Zhang Y, Ravid K. Characterization of the mouse cyclin D3 gene: exon/intron organization and promoter activity. Genomics. 1996 Jul 1; 35(1):156-63. PMID: 8661116
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Zhang Y, Wang Z, Ravid K. The cell cycle in polyploid megakaryocytes is associated with reduced activity of cyclin B1-dependent cdc2 kinase. J Biol Chem. 1996 Feb 23; 271(8):4266-72. PMID: 8626773
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Thompson A, Zhao Z, Ladd D, Zimmet J, Ravid K. A new transgenic mouse model for the study of cell cycle control in megakaryocytes. Stem Cells. 1996; 14 Suppl 1:181-7. PMID: 11012219
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Wang Z, Zhang Y, Kamen D, Lees E, Ravid K. Cyclin D3 is essential for megakaryocytopoiesis. Blood. 1995 Nov 15; 86(10):3783-8. PMID: 7579345
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Zhao Z, Ravid S, Ravid K. Chromosomal mapping of the mouse A3 adenosine receptor gene, Adora3. Genomics. 1995 Nov 1; 30(1):118-9. PMID: 8595892
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Ravid K, Kuter DJ, Rosenberg RD. rmIL-6 stimulates the transcriptional activity of the rat PF4 gene. Exp Hematol. 1995 May; 23(5):397-401. PMID: 7720812
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Block KL, Ravid K, Phung QH, Poncz M. Characterization of regulatory elements in the 5'-flanking region of the rat GPIIb gene by studies in a primary rat marrow culture system. Blood. 1994 Nov 15; 84(10):3385-93. PMID: 7949093
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Ravid K, Li YC, Rayburn HB, Rosenberg RD. Targeted expression of a conditional oncogene in hematopoietic cells of transgenic mice. J Cell Biol. 1993 Dec; 123(6 Pt 1):1545-53. PMID: 8253849; PMCID: PMC2290873
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Ravid K, Kuter DJ, Beeler DL, Doi T, Rosenberg RD. Selection of an HEL-derived cell line expressing high levels of platelet factor 4. Blood. 1993 Jun 1; 81(11):2885-90. PMID: 8499627
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Grabarek J, Raychowdhury M, Ravid K, Kent KC, Newman PJ, Ware JA. Identification and functional characterization of protein kinase C isozymes in platelets and HEL cells. J Biol Chem. 1992 May 15; 267(14):10011-7. PMID: 1374394
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Ravid K, Doi T, Beeler DL, Kuter DJ, Rosenberg RD. Transcriptional regulation of the rat platelet factor 4 gene: interaction between an enhancer/silencer domain and the GATA site. Mol Cell Biol. 1991 Dec; 11(12):6116-27. PMID: 1944279; PMCID: PMC361789
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Ravid K, Beeler DL, Rabin MS, Ruley HE, Rosenberg RD. Selective targeting of gene products with the megakaryocyte platelet factor 4 promoter. Proc Natl Acad Sci U S A. 1991 Feb 15; 88(4):1521-5. PMID: 1899930; PMCID: PMC51051
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Ravid K, Rosenthal RA, Doctrow SR, Lowenstein JM. 28 kDa adenosine-binding proteins of brain and other tissues. Biochem J. 1989 Mar 15; 258(3):653-61.View Related Profiles. PMID: 2730563; PMCID: PMC1138416
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Ravid K, Lowenstein JM. Changes in adenosine receptors during differentiation of 3T3-F442A cells to adipocytes. Biochem J. 1988 Jan 15; 249(2):377-81. PMID: 2829856; PMCID: PMC1148714
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Ravid K, Diamant P, Avi-Dor Y. Interrelation between salvage of purine nucleotides and protein synthesis in rat heart cells. Arch Biochem Biophys. 1985 Jan; 236(1):159-66. PMID: 3966790
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Ravid K, Diamant P, Avi-Dor Y. Regulation of the salvage pathway of purine nucleotide synthesis by the oxidation state of NAD+ in rat heart cells. Arch Biochem Biophys. 1984 Mar; 229(2):632-9. PMID: 6200076
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Ravid K, Lavie L, Gershon D. The presence of NADPH-glyceraldehyde 3-phosphate oxidoreductase in macrophages. FEBS Lett. 1983 Oct 3; 162(1):107-11. PMID: 6617882
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Ravid K, Avi-Dor Y. Spectrophotometric determination of cyanide based on the formation of NAD+-cyanide addition compound. Anal Biochem. 1980 Nov 1; 108(2):343-5. PMID: 7457878
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Ravid K, Diamant P, Avi-Dor Y. Glucose-dependent stimulation of protein synthesis in cultured heart muscle cells. Possible involvement of the pentose phosphate pathway. FEBS Lett. 1980 Sep 22; 119(1):20-4. PMID: 6775978
This graph shows the total number of publications by year, by first, middle/unknown,
or last author.
| Year | Publications |
|---|
| 1980 | 2 |
| 1983 | 1 |
| 1984 | 1 |
| 1985 | 1 |
| 1988 | 1 |
| 1989 | 1 |
| 1991 | 2 |
| 1992 | 1 |
| 1993 | 2 |
| 1994 | 1 |
| 1995 | 3 |
| 1996 | 4 |
| 1997 | 3 |
| 1998 | 2 |
| 1999 | 7 |
| 2000 | 3 |
| 2001 | 3 |
| 2002 | 8 |
| 2003 | 3 |
| 2004 | 5 |
| 2005 | 4 |
| 2006 | 4 |
| 2007 | 2 |
| 2008 | 13 |
| 2009 | 9 |
| 2010 | 7 |
| 2011 | 7 |
| 2012 | 10 |
| 2013 | 10 |
| 2014 | 7 |
| 2015 | 4 |
| 2016 | 4 |
| 2017 | 8 |
| 2018 | 5 |
| 2019 | 5 |
| 2020 | 5 |
| 2021 | 2 |
| 2022 | 4 |
2021 Boston University School of Medicine:
Barbara E. Corkey Endowed Professorship of Medicine
2020 Boston University School of Medicine:
Robert Dawson Evans Research Mentoring Award
2018-2022 Massachusetts Academy of Sciences :
President
2016 Fulbright :
Fulbright Research Scholar Award
2016-2017 Aarhus University, Denmark :
International Advisory Board
2014 Weizmann Institute:
Weizmann Institute Professorship Award
2014 American Association for the Advancement of Science:
Elected Fellow
2013 Boston University School of Medicine:
Robert Dawson Evans Special Recognition Teaching Award
2013-2016 American Society of Hematology:
Chair, Thrombosis and Vascular Biology Scientific Committee
2011-2013 Gordon Research Conference-Cell Biology of Megakaryocytes and Platelets:
Vice Chair & Chair
2009 University of Sydney :
International Visiting Professor Fellowship Award
2006 Boston University School of Medicine :
Educator of the Year Award, Graduate Medical Sciences
2000-2005 American Heart Association:
Established Investigator Award
1997 American Heart Association:
Grant-In-Aid Award for Young Investigators
1987 Weizmann Institute:
Weizmann Postdoctoral Fellowship Award
1982 Technion:
Gutwirth Prize for Outstanding Graduate Students
Our mission as researchers is not complete, if at all achievable, without enhancing the research experiences of trainees and faculty, and cultivating the next generation of accomplished scientists, regardless of age, gender and race. KR
Available to Mentor as: (Review Mentor Role Definitions):
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Advisor
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Career Mentor
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Co-Mentor or Peer Mentor
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Research / Scholarly Mentor