Keywords
Last Name

Kenneth H. Albrecht, PhD

TitleAssistant Professor
InstitutionBoston University School of Medicine
DepartmentMedicine
DivisionMolecular Medicine (Biomolecular Medicine Unit)
Address75 E. Newton St Evans Building
Boston MA 02118
Phone(617) 638-5821
ORCID ORCID Icon0000-0002-9769-3362
Other Positions
TitleGraduate Faculty (Primary Mentor of Grad Students)
InstitutionBoston University School of Medicine, Division of Graduate Medical Sciences

 Research Expertise & Professional Interests
Research in my laboratory is aimed at understanding the molecular mechanisms of cell fate specification during mammalian sex determination and fetal gonad organogenesis. I am broadly trained in classical genetics, molecular genetics, genomics and developmental biology, and have published widely in the field of mouse genetics and specifically in the developmental genetics of gonad organogenesis and sex determination.

 Self-Described Keywords
  • Developmental Biology
  • Genetics
  • Mice
  • Stem Cells
 Publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
List All   |   Timeline
  1. Wake C, Labadorf A, Dumitriu A, Hoss AG, Bregu J, Albrecht KH, DeStefano AL, Myers RH. Novel microRNA discovery using small RNA sequencing in post-mortem human brain. BMC Genomics. 2016 Oct 04; 17(1):776. PMID: 27716130.
    View in: PubMed
  2. Correa SM, Washburn LL, Kahlon RS, Musson MC, Bouma GJ, Eicher EM, Albrecht KH. Sex reversal in C57BL/6J XY mice caused by increased expression of ovarian genes and insufficient activation of the testis determining pathway. PLoS Genet. 2012; 8(4):e1002569. PMID: 22496664.
    View in: PubMed
  3. Pazin DE, Albrecht KH. Developmental expression of Smoc1 and Smoc2 suggests potential roles in fetal gonad and reproductive tract differentiation. Dev Dyn. 2009 Nov; 238(11):2877-90. PMID: 19842175.
    View in: PubMed
  4. Lee HJ, Pazin DE, Kahlon RS, Correa SM, Albrecht KH. Novel markers of early ovarian pre-granulosa cells are expressed in an Sry-like pattern. Dev Dyn. 2009 Apr; 238(4):812-25. PMID: 19301398.
    View in: PubMed
  5. Liu P, Pazin DE, Merson RR, Albrecht KH, Vaziri C. The developmentally-regulated Smoc2 gene is repressed by Aryl-hydrocarbon receptor (Ahr) signaling. Gene. 2009 Mar 15; 433(1-2):72-80. PMID: 19146932.
    View in: PubMed
  6. Liu L, Brown D, McKee M, Lebrasseur NK, Yang D, Albrecht KH, Ravid K, Pilch PF. Deletion of Cavin/PTRF causes global loss of caveolae, dyslipidemia, and glucose intolerance. Cell Metab. 2008 Oct; 8(4):310-7. PMID: 18840361.
    View in: PubMed
  7. Izvolsky KI, Lu J, Martin G, Albrecht KH, Cardoso WV. Systemic inactivation of Hs6st1 in mice is associated with late postnatal mortality without major defects in organogenesis. Genesis. 2008 Jan; 46(1):8-18. PMID: 18196599.
    View in: PubMed
  8. Bouma GJ, Washburn LL, Albrecht KH, Eicher EM. Correct dosage of Fog2 and Gata4 transcription factors is critical for fetal testis development in mice. Proc Natl Acad Sci U S A. 2007 Sep 18; 104(38):14994-9. PMID: 17848526.
    View in: PubMed
  9. Thevenet L, Albrecht KH, Malki S, Berta P, Boizet-Bonhoure B, Poulat F. NHERF2/SIP-1 interacts with mouse SRY via a different mechanism than human SRY. J Biol Chem. 2005 Nov 18; 280(46):38625-30. PMID: 16166090.
    View in: PubMed
  10. Bouma GJ, Albrecht KH, Washburn LL, Recknagel AK, Churchill GA, Eicher EM. Gonadal sex reversal in mutant Dax1 XY mice: a failure to upregulate Sox9 in pre-Sertoli cells. Development. 2005 Jul; 132(13):3045-54. PMID: 15944188.
    View in: PubMed
  11. Albrecht KH, Young M, Washburn LL, Eicher EM. Sry expression level and protein isoform differences play a role in abnormal testis development in C57BL/6J mice carrying certain Sry alleles. Genetics. 2003 May; 164(1):277-88. PMID: 12750339.
    View in: PubMed
  12. Tevosian SG, Albrecht KH, Crispino JD, Fujiwara Y, Eicher EM, Orkin SH. Gonadal differentiation, sex determination and normal Sry expression in mice require direct interaction between transcription partners GATA4 and FOG2. Development. 2002 Oct; 129(19):4627-34. PMID: 12223418.
    View in: PubMed
  13. Albrecht KH, Eicher EM. Evidence that Sry is expressed in pre-Sertoli cells and Sertoli and granulosa cells have a common precursor. Dev Biol. 2001 Dec 1; 240(1):92-107. PMID: 11784049.
    View in: PubMed
  14. Washburn LL, Albrecht KH, Eicher EM. C57BL/6J-T-associated sex reversal in mice is caused by reduced expression of a Mus domesticus Sry allele. Genetics. 2001 Aug; 158(4):1675-81. PMID: 11514455.
    View in: PubMed
  15. Bergstrom DE, Young M, Albrecht KH, Eicher EM. Related function of mouse SOX3, SOX9, and SRY HMG domains assayed by male sex determination. Genesis. 2000 Nov-Dec; 28(3-4):111-24. PMID: 11105052.
    View in: PubMed
  16. Albrecht KH, Capel B, Washburn LL, Eicher EM. Defective mesonephric cell migration is associated with abnormal testis cord development in C57BL/6J XY(Mus domesticus) mice. Dev Biol. 2000 Sep 1; 225(1):26-36. PMID: 10964462.
    View in: PubMed
  17. Capel B, Albrecht KH, Washburn LL, Eicher EM. Migration of mesonephric cells into the mammalian gonad depends on Sry. Mech Dev. 1999 Jun; 84(1-2):127-31. PMID: 10473126.
    View in: PubMed
  18. Albrecht KH, Eicher EM. DNA sequence analysis of Sry alleles (subgenus Mus) implicates misregulation as the cause of C57BL/6J-Y(POS) sex reversal and defines the SRY functional unit. Genetics. 1997 Nov; 147(3):1267-77. PMID: 9383069.
    View in: PubMed
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