Kenneth H. Albrecht, PhD
Adjunct Assistant Professor
Boston University Chobanian & Avedisian School of Medicine
Medicine
Biomedical Genetics

PhD, University of Connecticut
BS, Stony Brook University



Research in my laboratory is aimed at understanding the molecular mechanisms of cell fate specification during mammalian sex determination and fetal gonad organogenesis. I am broadly trained in classical genetics, molecular genetics, genomics and developmental biology, and have published widely in the field of mouse genetics and specifically in the developmental genetics of gonad organogenesis and sex determination.

Member
Boston University
Evans Center for Interdisciplinary Biomedical Research




Cyclin G-associated kinase as a novel target for Parkinson's disease
01/01/2017 - 12/31/2019 (Co-Investigator)
PI: Richard H. Myers, PhD
Ellison Foundation


Genetic and Genomic Analysis of Ovarian Granulosa Cell Differentiation
01/01/2006 - 12/31/2009 (PI)
American Cancer Society



Title


Yr Title Project-Sub Proj Pubs
2007 Genetic Mechanisms of Mammalian Sex Determination 5R01HD042779-05 7
2006 Genetic Mechanisms of Mammalian Sex Determination 5R01HD042779-04 7
2005 Genetic Mechanisms of Mammalian Sex Determination 5R01HD042779-03 7
2004 Genetic Mechanisms of Mammalian Sex Determination 5R01HD042779-02 7
2003 Genetic Mechanisms of Mammalian Sex Determination 1R01HD042779-01A1 7
1995 POSITIONAL CLONING OF A PRIMARY SEX DETERMINATION GENE 5F32GM016726-02
1994 POSITIONAL CLONING OF A PRIMARY SEX DETERMINATION GENE 1F32GM016726-01

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Wake C, Labadorf A, Dumitriu A, Hoss AG, Bregu J, Albrecht KH, DeStefano AL, Myers RH. Novel microRNA discovery using small RNA sequencing in post-mortem human brain. BMC Genomics. 2016 Oct 04; 17(1):776.View Related Profiles. PMID: 27716130; PMCID: PMC5050850; DOI: 10.1186/s12864-016-3114-3;
     
  2. Correa SM, Washburn LL, Kahlon RS, Musson MC, Bouma GJ, Eicher EM, Albrecht KH. Sex reversal in C57BL/6J XY mice caused by increased expression of ovarian genes and insufficient activation of the testis determining pathway. PLoS Genet. 2012; 8(4):e1002569. PMID: 22496664; PMCID: PMC3320579; DOI: 10.1371/journal.pgen.1002569;
     
  3. Pazin DE, Albrecht KH. Developmental expression of Smoc1 and Smoc2 suggests potential roles in fetal gonad and reproductive tract differentiation. Dev Dyn. 2009 Nov; 238(11):2877-90. PMID: 19842175; PMCID: PMC3070464; DOI: 10.1002/dvdy.22124;
     
  4. Lee HJ, Pazin DE, Kahlon RS, Correa SM, Albrecht KH. Novel markers of early ovarian pre-granulosa cells are expressed in an Sry-like pattern. Dev Dyn. 2009 Apr; 238(4):812-25.View Related Profiles. PMID: 19301398; PMCID: PMC3100217; DOI: 10.1002/dvdy.21902;
     
  5. Liu P, Pazin DE, Merson RR, Albrecht KH, Vaziri C. The developmentally-regulated Smoc2 gene is repressed by Aryl-hydrocarbon receptor (Ahr) signaling. Gene. 2009 Mar 15; 433(1-2):72-80.View Related Profiles. PMID: 19146932; PMCID: PMC2652666; DOI: 10.1016/j.gene.2008.12.010;
     
  6. Liu L, Brown D, McKee M, Lebrasseur NK, Yang D, Albrecht KH, Ravid K, Pilch PF. Deletion of Cavin/PTRF causes global loss of caveolae, dyslipidemia, and glucose intolerance. Cell Metab. 2008 Oct; 8(4):310-7.View Related Profiles. PMID: 18840361; PMCID: PMC2581738; DOI: 10.1016/j.cmet.2008.07.008;
     
  7. Izvolsky KI, Lu J, Martin G, Albrecht KH, Cardoso WV. Systemic inactivation of Hs6st1 in mice is associated with late postnatal mortality without major defects in organogenesis. Genesis. 2008 Jan; 46(1):8-18.View Related Profiles. PMID: 18196599; DOI: 10.1002/dvg.20355;
     
  8. Bouma GJ, Washburn LL, Albrecht KH, Eicher EM. Correct dosage of Fog2 and Gata4 transcription factors is critical for fetal testis development in mice. Proc Natl Acad Sci U S A. 2007 Sep 18; 104(38):14994-9. PMID: 17848526; PMCID: PMC1986601; DOI: 10.1073/pnas.0701677104;
     
  9. Thevenet L, Albrecht KH, Malki S, Berta P, Boizet-Bonhoure B, Poulat F. NHERF2/SIP-1 interacts with mouse SRY via a different mechanism than human SRY. J Biol Chem. 2005 Nov 18; 280(46):38625-30. PMID: 16166090
     
  10. Bouma GJ, Albrecht KH, Washburn LL, Recknagel AK, Churchill GA, Eicher EM. Gonadal sex reversal in mutant Dax1 XY mice: a failure to upregulate Sox9 in pre-Sertoli cells. Development. 2005 Jul; 132(13):3045-54. PMID: 15944188
     
Showing 10 of 18 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 18 publications over 12 distinct years, with a maximum of 3 publications in 2008

YearPublications
19971
19991
20002
20012
20021
20031
20052
20071
20083
20092
20121
20161

In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Developmental Biology
Genetics
Mice
Stem Cells
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Boston MA 02118
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