Richard H. Myers, PhD
Professor Emeritus
Boston University Chobanian & Avedisian School of Medicine
Neurology

PhD, Georgia State University
MA, Georgia State University
MEd, Georgia State University
BA, University of Kansas



Dr. Richard H. Myers retired in 2020 and is now Emeritus Professor of Neurology at Chobanian and Avedisian School of Medicine. He is no longer accepting students or post-doctoral fellows.

Dr. Myers' professional interests focused upon the application of genetic research methods for the investigation of adult onset diseases with complex etiology (Parkinson’s disease, coronary heart disease, Alzheimer’s disease, obesity, pulmonary function, osteoarthritis, osteoporosis etc.). Dr. Myers has had a long-standing interest in Huntington’s disease and has participated in a wide range of research investigations for this disease. He was a member of the New England Huntington’s disease "Center Without Walls" since its inception in 1980. His HD studies are best characterized as ‘Neurobiological Studies’ in that they include studies into the mechanisms of disease expression, including complex genetic modifier studies and a series of neuropathological studies of effects of disease expression in the brain. Additional interests include ethical issues influencing utilization of genetic test procedures.

Dr. Myers has been involved in a number of studies in positional cloning. He also participated in the cloning of the gene for Huntington’s disease in 1993. He initiated the genome scan project in the Framingham Study, and a genome scan in Parkinson’s disease. Dr. Myers' Parkinson’s disease genetic linkage study, known as the "GenePD" study, involved an international collaboration of twenty clinical centers in Parkinson’s disease. The study sought genetic loci involved in risk for PD. From 1993 he has participated in genetic linkage studies for hypertension (the HyperGEN study, one of the NHLBI Family Blood Pressure Program Project studies), and the genome scan in the NHLBI Family Heart Study.

Dr. Myers has published more than 300 peer reviewed articles, 38 individual NIH funded grants, and mentored many extraordinarily talented students and post-docs.

Boston Medical Center




Cyclin G-associated kinase as a novel target for Parkinson's disease
01/01/2017 - 12/31/2019 (PI)
Ellison Foundation


Functional analysis of Disease associated risk alleles in sporadic Parkinson's disease
09/23/2014 - 06/30/2019 (Multi-PI)
PI: Richard H. Myers, PhD
Whitehead Institute for Biomedical Research NIH NINDS
5R01NS088538-05

Probing the Dark Matter of the Genome in the NHLBI Family Heart Study
07/01/2016 - 06/30/2018 (Subcontract PI)
The Washington University NIH NHLBI
4R01HL117078-04

Epigenetic Markers in Huntington's Disease Brain
07/01/2011 - 04/30/2017 (PI)
NIH/National Institute of Neurological Disorders & Stroke
3R01NS073947-05S1

Probing the Dark Matter of the Genome in the NHLBI Family Heart Study
07/22/2013 - 06/30/2016 (Subcontract PI)
The Washington University NIH NHLBI
5R01HL117078-03

Epigenetic Markers of Huntington Disease Brain
07/01/2011 - 04/30/2016 (PI)
NIH/National Institute of Neurological Disorders & Stroke
1 R01 NS073947 01

Characterization of the role of cyclin G-associated kinase in Parkinson disease
09/01/2011 - 04/30/2015 (PI)
NIH/National Institute of Neurological Disorders & Stroke
5R01NS076843-03

Genomic Scan for Atherosclerosis Pathway Genes in African Americans from FHS Scan
05/15/2008 - 04/30/2013 (Subcontract PI)
The Washington University NIH NHLBI
5R01HL088215-04

Identifying Susceptibility Genes for Metabolic Syndrome
01/29/2007 - 12/31/2011 (Subcontract PI)
Regents of the University of Minnesota NIH NIDDK
5R01DK068320-03

Mapping Adiposity QTLs in the NHLBI Family Heart Study
09/20/2004 - 06/30/2009 (PI)
Washington University, St Louis NIH NIDDK

Showing 10 of 12 results. Show All Results


Title


Yr Title Project-Sub Proj Pubs
2018 An iPSC based platform for functionally assessing genetic and environmental risk 5R01NS088538-05 32
2017 An iPSC based platform for functionally assessing genetic and environmental risk 5R01NS088538-04 32
2016 An iPSC based platform for functionally assessing genetic and environmental risk 5R01NS088538-03 32
2015 An iPSC based platform for functionally assessing genetic and environmental risk 5R01NS088538-02 32
2015 Epigenetic Markers in Huntington's disease Brain 3R01NS073947-05S1 33
2015 Epigenetic Markers in Huntington's disease Brain 5R01NS073947-05 33
2014 An iPSC based platform for functionally assessing genetic and environmental risk 1R01NS088538-01 32
2014 Epigenetic Markers in Huntington's disease Brain 5R01NS073947-04 33
2013 Characterization of the role of cyclin G-associated kinase in Parkinson disease 5R01NS076843-03 14
2013 Epigenetic Markers in Huntington's disease Brain 5R01NS073947-03 33
Showing 10 of 34 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Website       Copy PMIDs To Clipboard

  1. Rehman Z, Edington K, Jamal Z, Kritz-Wilson A, Dudas G, Sims S, Myers R, Afrough B, Inamdar L, Haider SA, Ikram A, Salman M, Umair M. The introduction of the SARS-CoV-2 BA.4 lineage into Pakistan. Arch Virol. 2025 Jan 06; 170(2):26. PMID: 39762542
     
  2. Dayama G, Gupta S, Connizzo BK, Labadorf AT, Myers RH, Lau NC. Transposable element small and long RNAs in aging brains and implications in Huntington's and Parkinson's disease. bioRxiv. 2024 Oct 25.View Related Profiles. PMID: 39484439; PMCID: PMC11526979; DOI: 10.1101/2024.10.22.619758;
     
  3. Lee JM, McLean ZL, Correia K, Shin JW, Lee S, Jang JH, Lee Y, Kim KH, Choi DE, Long JD, Lucente D, Seong IS, Pinto RM, Giordano JV, Mysore JS, Siciliano J, Elezi E, Ruliera J, Gillis T, Wheeler VC, MacDonald ME, Gusella JF, Gatseva A, Ciosi M, Lomeikaite V, Loay H, Monckton DG, Wills C, Massey TH, Jones L, Holmans P, Kwak S, Sampaio C, Orth M, Bernhard Landwehrmeyer G, Paulsen JS, Ray Dorsey E, Myers RH. Genetic modifiers of somatic expansion and clinical phenotypes in Huntington's disease reveal shared and tissue-specific effects. bioRxiv. 2024 Jun 18. PMID: 38948755; PMCID: PMC11212857; DOI: 10.1101/2024.06.10.597797;
     
  4. Nazeen S, Wang X, Zielinski D, Lam I, Hallacli E, Xu P, Ethier E, Strom R, Zanella CA, Nithianandam V, Ritter D, Henderson A, Saurat N, Afroz J, Nutter-Upham A, Benyamini H, Copty J, Ravishankar S, Morrow A, Mitchel J, Neavin D, Gupta R, Farbehi N, Grundman J, Myers RH, Scherzer CR, Trojanowski JQ, Van Deerlin VM, Cooper AA, Lee EB, Erlich Y, Lindquist S, Peng J, Geschwind DH, Powell J, Studer L, Feany MB, Sunyaev SR, Khurana V. Deep sequencing of proteotoxicity modifier genes uncovers a Presenilin-2/beta-amyloid-actin genetic risk module shared among alpha-synucleinopathies. bioRxiv. 2024 Mar 07. PMID: 38496508; PMCID: PMC10942362; DOI: 10.1101/2024.03.03.583145;
     
  5. Cogdale J, Kele B, Myers R, Harvey R, Lofts A, Mikaiel T, Hoschler K, Banyard AC, James J, Mollett BC, Byrne AM, Lopez-Bernal J, Watson CH, Chand M, Welfare W, Williamson DA, Oliver I, Padfield S, Lee A, Calvert S, Bewley MA, Wallace L, deLusignan S, Lewis NS, Brown IH, Zambon M. A case of swine influenza A(H1N2)v in England, November 2023. Euro Surveill. 2024 Jan; 29(3). PMID: 38240057; PMCID: PMC10797662; DOI: 10.2807/1560-7917.ES.2024.29.3.2400002;
     
  6. Twohig KA, Harman K, Zaidi A, Aliabadi S, Nash SG, Sinnathamby M, Harrison I, Gallagher E, Groves N, Schwach F, Pearson C, Thornton A, Myers R, Chand M, Thelwall S, Dabrera G. Representativeness of whole-genome sequencing approaches in England: the importance for understanding inequalities associated with SARS-CoV-2 infection. Epidemiol Infect. 2023 Sep 20; 151:e169. PMID: 37726109; PMCID: PMC10600896; DOI: 10.1017/S0950268823001541;
     
  7. Hotta R, Pan W, Bhave S, Nagy N, Stavely R, Ohkura T, Krishnan K, de Couto G, Myers R, Rodriguez-Borlado L, Burns AJ, Goldstein AM. Isolation, Expansion, and Endoscopic Delivery of Autologous Enteric Neuronal Stem Cells in Swine. Cell Transplant. 2023; 32:9636897231215233. PMID: 38049927; PMCID: PMC10697035; DOI: 10.1177/09636897231215233;
     
  8. Virginio C, Aldegheri L, Nola S, Brodbeck D, Brault L, Raveglia LF, Barilli A, Sabat M, Myers R. Identification of positive modulators of TRPM5 channel from a high-throughput screen using a fluorescent membrane potential assay. SLAS Discov. 2022 Jan; 27(1):55-64. PMID: 35058176
     
  9. Ruan Z, Haley E, Orozco IJ, Sabat M, Myers R, Roth R, Du J, Lü W. Author Correction: Structures of the TRPM5 channel elucidate mechanisms of activation and inhibition. Nat Struct Mol Biol. 2021 Aug; 28(8):702. PMID: 34285419
     
  10. Hyeon SJ, Park J, Yoo J, Kim SH, Hwang YJ, Kim SC, Liu T, Shim HS, Kim Y, Cho Y, Woo J, Kim KS, Myers RH, Ryu HL, Kowall NW, Song EJ, Hwang EM, Seo H, Lee J, Ryu H. Dysfunction of X-linked inhibitor of apoptosis protein (XIAP) triggers neuropathological processes via altered p53 activity in Huntington's disease. Prog Neurobiol. 2021 09; 204:102110.View Related Profiles. PMID: 34166773; PMCID: PMC8364511; DOI: 10.1016/j.pneurobio.2021.102110;
     
Showing 10 of 357 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 352 publications over 44 distinct years, with a maximum of 17 publications in 2002

YearPublications
19801
19824
19832
19844
19855
19862
19879
19884
198913
19905
19917
199212
199312
19947
19958
19966
199711
199812
199911
200016
200113
200217
200313
200410
200510
200616
200713
200815
20099
20106
20117
201213
20134
20146
201511
201611
20176
20184
20192
20202
20216
20232
20244
20251

In addition to these self-described keywords below, a list of MeSH based concepts is available here.

coronary heart disease
genetic testing
Huntington's disease
Neurogenetics
Parkinson's disease
risk factors
Contact for Mentoring:

75 E. Newton St Evans Building
Boston MA 02118
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