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Lee JM, Chao MJ, Harold D, Abu Elneel K, Gillis T, Holmans P, Jones L, Orth M, Myers RH, Kwak S, Wheeler VC, MacDonald ME, Gusella JF. A modifier of Huntington's disease onset at the MLH1 locus. Hum Mol Genet. 2017 Oct 01; 26(19):3859-3867. PMID: 28934397; PMCID: PMC6455020; DOI: 10.1093/hmg/ddx286;
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Chao MJ, Gillis T, Atwal RS, Mysore JS, Arjomand J, Harold D, Holmans P, Jones L, Orth M, Myers RH, Kwak S, Wheeler VC, MacDonald ME, Gusella JF, Lee JM. Haplotype-based stratification of Huntington's disease. Eur J Hum Genet. 2017 Nov; 25(11):1202-1209. PMID: 28832564; PMCID: PMC5643960; DOI: 10.1038/ejhg.2017.125;
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Neueder A, Landles C, Ghosh R, Howland D, Myers RH, Faull RLM, Tabrizi SJ, Bates GP. The pathogenic exon 1 HTT protein is produced by incomplete splicing in Huntington's disease patients. Sci Rep. 2017 05 02; 7(1):1307. PMID: 28465506; PMCID: PMC5431000; DOI: 10.1038/s41598-017-01510-z;
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Labadorf A, Hoss AG, Myers RH. Neuroimmune Pharmacology. Huntington’s Disease. 2017. View Publication
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Trinh J, Gustavsson EK, Vilariño-Güell C, Bortnick S, Latourelle J, McKenzie MB, Tu CS, Nosova E, Khinda J, Milnerwood A, Lesage S, Brice A, Tazir M, Aasly JO, Parkkinen L, Haytural H, Foroud T, Myers RH, Sassi SB, Hentati E, Nabli F, Farhat E, Amouri R, Hentati F, Farrer MJ. DNM3 and genetic modifiers of age of onset in LRRK2 Gly2019Ser parkinsonism: a genome-wide linkage and association study. Lancet Neurol. 2016 Nov; 15(12):1248-1256.View Related Profiles. PMID: 27692902; DOI: 10.1016/S1474-4422(16)30203-4;
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Nielson CM, Liu CT, Smith AV, Ackert-Bicknell CL, Reppe S, Jakobsdottir J, Wassel C, Register TC, Oei L, Alonso N, Oei EH, Parimi N, Samelson EJ, Nalls MA, Zmuda J, Lang T, Bouxsein M, Latourelle J, Claussnitzer M, Siggeirsdottir K, Srikanth P, Lorentzen E, Vandenput L, Langefeld C, Raffield L, Terry G, Cox AJ, Allison MA, Criqui MH, Bowden D, Ikram MA, Mellström D, Karlsson MK, Carr J, Budoff M, Phillips C, Cupples LA, Chou WC, Myers RH, Ralston SH, Gautvik KM, Cawthon PM, Cummings S, Karasik D, Rivadeneira F, Gudnason V, Orwoll ES, Harris TB, Ohlsson C, Kiel DP, Hsu YH. Novel Genetic Variants Associated With Increased Vertebral Volumetric BMD, Reduced Vertebral Fracture Risk, and Increased Expression of SLC1A3 and EPHB2. J Bone Miner Res. 2016 Dec; 31(12):2085-2097.View Related Profiles. PMID: 27476799; PMCID: PMC5477772; DOI: 10.1002/jbmr.2913;
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Labadorf A, Hoss AG, Lagomarsino V, Latourelle JC, Hadzi TC, Bregu J, MacDonald ME, Gusella JF, Chen JF, Akbarian S, Weng Z, Myers RH. Correction: RNA Sequence Analysis of Human Huntington Disease Brain Reveals an Extensive Increase in Inflammatory and Developmental Gene Expression. PLoS One. 2016; 11(7):e0160295.View Related Profiles. PMID: 27454300; PMCID: PMC4959683; DOI: 10.1371/journal.pone.0160295;
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Soldner F, Stelzer Y, Shivalila CS, Abraham BJ, Latourelle JC, Barrasa MI, Goldmann J, Myers RH, Young RA, Jaenisch R. Parkinson-associated risk variant in distal enhancer of a-synuclein modulates target gene expression. Nature. 2016 May 5; 533(7601):95-9.View Related Profiles. PMID: 27096366; PMCID: PMC5042324; DOI: 10.1038/nature17939;
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Kilpeläinen TO, Carli JF, Skowronski AA, Sun Q, Kriebel J, Feitosa MF, Hedman ÅK, Drong AW, Hayes JE, Zhao J, Pers TH, Schick U, Grarup N, Kutalik Z, Trompet S, Mangino M, Kristiansson K, Beekman M, Lyytikäinen LP, Eriksson J, Henneman P, Lahti J, Tanaka T, Luan J, Del Greco M F, Pasko D, Renström F, Willems SM, Mahajan A, Rose LM, Guo X, Liu Y, Kleber ME, Pérusse L, Gaunt T, Ahluwalia TS, Ju Sung Y, Ramos YF, Amin N, Amuzu A, Barroso I, Bellis C, Blangero J, Buckley BM, Böhringer S, I Chen YD, de Craen AJ, Crosslin DR, Dale CE, Dastani Z, Day FR, Deelen J, Delgado GE, Demirkan A, Finucane FM, Ford I, Garcia ME, Gieger C, Gustafsson S, Hallmans G, Hankinson SE, Havulinna AS, Herder C, Hernandez D, Hicks AA, Hunter DJ, Illig T, Ingelsson E, Ioan-Facsinay A, Jansson JO, Jenny NS, Jørgensen ME, Jørgensen T, Karlsson M, Koenig W, Kraft P, Kwekkeboom J, Laatikainen T, Ladwig KH, LeDuc CA, Lowe G, Lu Y, Marques-Vidal P, Meisinger C, Menni C, Morris AP, Myers RH, Männistö S, Nalls MA, Paternoster L, Peters A, Pradhan AD, Rankinen T, Rasmussen-Torvik LJ, Rathmann W, Rice TK, Brent Richards J, Ridker PM, Sattar N, Savage DB, Söderberg S, Timpson NJ, Vandenput L, van Heemst D, Uh HW, Vohl MC, Walker M, Wichmann HE, Widén E, Wood AR, Yao J, Zeller T, Zhang Y, Meulenbelt I, Kloppenburg M, Astrup A, Sørensen TI, Sarzynski MA, Rao DC, Jousilahti P, Vartiainen E, Hofman A, Rivadeneira F, Uitterlinden AG, Kajantie E, Osmond C, Palotie A, Eriksson JG, Heliövaara M, Knekt PB, Koskinen S, Jula A, Perola M, Huupponen RK, Viikari JS, Kähönen M, Lehtimäki T, Raitakari OT, Mellström D, Lorentzon M, Casas JP, Bandinelli S, März W, Isaacs A, van Dijk KW, van Duijn CM, Harris TB, Bouchard C, Allison MA, Chasman DI, Ohlsson C, Lind L, Scott RA, Langenberg C, Wareham NJ, Ferrucci L, Frayling TM, Pramstaller PP, Borecki IB, Waterworth DM, Bergmann S, Waeber G, Vollenweider P, Vestergaard H, Hansen T, Pedersen O, Hu FB, Eline Slagboom P, Grallert H, Spector TD, Jukema JW, Klein RJ, Schadt EE, Franks PW, Lindgren CM, Leibel RL, Loos RJ. Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels. Nat Commun. 2016; 7:10494.View Related Profiles. PMID: 26833098; PMCID: PMC4740377; DOI: 10.1038/ncomms10494;
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Dumitriu A, Golji J, Labadorf AT, Gao B, Beach TG, Myers RH, Longo KA, Latourelle JC. Integrative analyses of proteomics and RNA transcriptomics implicate mitochondrial processes, protein folding pathways and GWAS loci in Parkinson disease. BMC Med Genomics. 2016; 9:5.View Related Profiles. PMID: 26793951; PMCID: PMC4722694; DOI: 10.1186/s12920-016-0164-y;
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Biglan KM, Shoulson I, Kieburtz K, Oakes D, Kayson E, Shinaman MA, Zhao H, Romer M, Young A, Hersch S, Penney J, Marder K, Paulsen J, Quaid K, Siemers E, Tanner C, Mallonee W, Suter G, Dubinsky R, Gray C, Nance M, Bundlie S, Radtke D, Kostyk S, Baic C, Caress J, Walker F, Hunt V, O'Neill C, Chouinard S, Factor S, Greenamyre T, Wood-Siverio C, Corey-Bloom J, Song D, Peavy G, Moskowitz C, Wesson M, Samii A, Bird T, Lipe H, Blindauer K, Marshall F, Zimmerman C, Goldstein J, Rosas D, Novak P, Caviness J, Adler C, Duffy A, Wheelock V, Tempkin T, Richman D, Seeberger L, Albin R, Chou KL, Racette B, Perlmutter JS, Perlman S, Bordelon Y, Martin W, Wieler M, Leavitt B, Raymond L, Decolongon J, Clarke L, Jankovic J, Hunter C, Hauser RA, Sanchez-Ramos J, Furtado S, Suchowersky O, Klimek ML, Guttman M, Sethna R, Feigin A, Cox M, Shannon B, Percy A, Dure L, Harrison M, Johnson W, Higgins D, Molho E, Nickerson C, Evans S, Hobson D, Singer C, Galvez-Jimenez N, Shannon K, Comella C, Ross C, Saint-Hilaire MH, Testa C, Rosenblatt A, Hogarth P, Weiner W, Como P, Kumar R, Cotto C, Stout J, Brocht A, Watts A, Eberly S, Weaver C, Foroud T, Gusella J, MacDonald M, Myers R, Fahn S, Shults C. Clinical-Genetic Associations in the Prospective Huntington at Risk Observational Study (PHAROS): Implications for Clinical Trials. JAMA Neurol. 2016 Jan; 73(1):102-10.View Related Profiles. PMID: 26569098; DOI: 10.1001/jamaneurol.2015.2736;
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Bates G, Osborne GF, Ali N, Benjamin C, Papadopoulou A, Howland D, Tabrizi SJ, Faull RLM, Myers RH, Landles C, Neueder A. B4 Detection of the aberrantly spliced exon 1 – intron 1 htt mRNA in HD patient post mortem brain tissue and fibroblast lines. Journal of Neurology Neurosurgery & Psychiatry. 2016; 87(Suppl 1):A10.2-A10. View Publication
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Labadorf A, Hoss AG, Lagomarsino V, Latourelle JC, Hadzi TC, Bregu J, MacDonald ME, Gusella JF, Chen JF, Akbarian S, Weng Z, Myers RH. RNA Sequence Analysis of Human Huntington Disease Brain Reveals an Extensive Increase in Inflammatory and Developmental Gene Expression. PLoS One. 2015; 10(12):e0143563.View Related Profiles. PMID: 26636579; PMCID: PMC4670106; DOI: 10.1371/journal.pone.0143563;
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Lee JM, Kim KH, Shin A, Chao MJ, Abu Elneel K, Gillis T, Mysore JS, Kaye JA, Zahed H, Kratter IH, Daub AC, Finkbeiner S, Li H, Roach JC, Goodman N, Hood L, Myers RH, MacDonald ME, Gusella JF. Sequence-Level Analysis of the Major European Huntington Disease Haplotype. Am J Hum Genet. 2015 Sep 3; 97(3):435-44. PMID: 26320893; PMCID: PMC4564985; DOI: 10.1016/j.ajhg.2015.07.017;
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Joshi PK, Esko T, Mattsson H, Eklund N, Gandin I, Nutile T, Jackson AU, Schurmann C, Smith AV, Zhang W, Okada Y, Stancáková A, Faul JD, Zhao W, Bartz TM, Concas MP, Franceschini N, Enroth S, Vitart V, Trompet S, Guo X, Chasman DI, O'Connel JR, Corre T, Nongmaithem SS, Chen Y, Mangino M, Ruggiero D, Traglia M, Farmaki AE, Kacprowski T, Bjonnes A, van der Spek A, Wu Y, Giri AK, Yanek LR, Wang L, Hofer E, Rietveld CA, McLeod O, Cornelis MC, Pattaro C, Verweij N, Baumbach C, Abdellaoui A, Warren HR, Vuckovic D, Mei H, Bouchard C, Perry JR, Cappellani S, Mirza SS, Benton MC, Broeckel U, Medland SE, Lind PA, Malerba G, Drong A, Yengo L, Bielak LF, Zhi D, van der Most PJ, Shriner D, Mägi R, Hemani G, Karaderi T, Wang Z, Liu T, Demuth I, Zhao JH, Meng W, Lataniotis L, van der Laan SW, Bradfield JP, Wood AR, Bonnefond A, Ahluwalia TS, Hall LM, Salvi E, Yazar S, Carstensen L, de Haan HG, Abney M, Afzal U, Allison MA, Amin N, Asselbergs FW, Bakker SJ, Barr RG, Baumeister SE, Benjamin DJ, Bergmann S, Boerwinkle E, Bottinger EP, Campbell A, Chakravarti A, Chan Y, Chanock SJ, Chen C, Chen YD, Collins FS, Connell J, Correa A, Cupples LA, Smith GD, Davies G, Dörr M, Ehret G, Ellis SB, Feenstra B, Feitosa MF, Ford I, Fox CS, Frayling TM, Friedrich N, Geller F, Scotland G, Gillham-Nasenya I, Gottesman O, Graff M, Grodstein F, Gu C, Haley C, Hammond CJ, Harris SE, Harris TB, Hastie ND, Heard-Costa NL, Heikkilä K, Hocking LJ, Homuth G, Hottenga JJ, Huang J, Huffman JE, Hysi PG, Ikram MA, Ingelsson E, Joensuu A, Johansson Å, Jousilahti P, Jukema JW, Kähönen M, Kamatani Y, Kanoni S, Kerr SM, Khan NM, Koellinger P, Koistinen HA, Kooner MK, Kubo M, Kuusisto J, Lahti J, Launer LJ, Lea RA, Lehne B, Lehtimäki T, Liewald DC, Lind L, Loh M, Lokki ML, London SJ, Loomis SJ, Loukola A, Lu Y, Lumley T, Lundqvist A, Männistö S, Marques-Vidal P, Masciullo C, Matchan A, Mathias RA, Matsuda K, Meigs JB, Meisinger C, Meitinger T, Menni C, Mentch FD, Mihailov E, Milani L, Montasser ME, Montgomery GW, Morrison A, Myers RH, Nadukuru R, Navarro P, Nelis M, Nieminen MS, Nolte IM, O'Connor GT, Ogunniyi A, Padmanabhan S, Palmas WR, Pankow JS, Patarcic I, Pavani F, Peyser PA, Pietilainen K, Poulter N, Prokopenko I, Ralhan S, Redmond P, Rich SS, Rissanen H, Robino A, Rose LM, Rose R, Sala C, Salako B, Salomaa V, Sarin AP, Saxena R, Schmidt H, Scott LJ, Scott WR, Sennblad B, Seshadri S, Sever P, Shrestha S, Smith BH, Smith JA, Soranzo N, Sotoodehnia N, Southam L, Stanton AV, Stathopoulou MG, Strauch K, Strawbridge RJ, Suderman MJ, Tandon N, Tang ST, Taylor KD, Tayo BO, Töglhofer AM, Tomaszewski M, Tšernikova N, Tuomilehto J, Uitterlinden AG, Vaidya D, van Hylckama Vlieg A, van Setten J, Vasankari T, Vedantam S, Vlachopoulou E, Vozzi D, Vuoksimaa E, Waldenberger M, Ware EB, Wentworth-Shields W, Whitfield JB, Wild S, Willemsen G, Yajnik CS, Yao J, Zaza G, Zhu X, Salem RM, Melbye M, Bisgaard H, Samani NJ, Cusi D, Mackey DA, Cooper RS, Froguel P, Pasterkamp G, Grant SF, Hakonarson H, Ferrucci L, Scott RA, Morris AD, Palmer CN, Dedoussis G, Deloukas P, Bertram L, Lindenberger U, Berndt SI, Lindgren CM, Timpson NJ, Tönjes A, Munroe PB, Sørensen TI, Rotimi CN, Arnett DK, Oldehinkel AJ, Kardia SL, Balkau B, Gambaro G, Morris AP, Eriksson JG, Wright MJ, Martin NG, Hunt SC, Starr JM, Deary IJ, Griffiths LR, Tiemeier H, Pirastu N, Kaprio J, Wareham NJ, Pérusse L, Wilson JG, Girotto G, Caulfield MJ, Raitakari O, Boomsma DI, Gieger C, van der Harst P, Hicks AA, Kraft P, Sinisalo J, Knekt P, Johannesson M, Magnusson PK, Hamsten A, Schmidt R, Borecki IB, Vartiainen E, Becker DM, Bharadwaj D, Mohlke KL, Boehnke M, van Duijn CM, Sanghera DK, Teumer A, Zeggini E, Metspalu A, Gasparini P, Ulivi S, Ober C, Toniolo D, Rudan I, Porteous DJ, Ciullo M, Spector TD, Hayward C, Dupuis J, Loos RJ, Wright AF, Chandak GR, Vollenweider P, Shuldiner AR, Ridker PM, Rotter JI, Sattar N, Gyllensten U, North KE, Pirastu M, Psaty BM, Weir DR, Laakso M, Gudnason V, Takahashi A, Chambers JC, et al. DirectionalView Related Profiles. PMID: 26131930; PMCID: PMC4516141; DOI: 10.1038/nature14618;
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Hoss AG, Labadorf A, Latourelle JC, Kartha VK, Hadzi TC, Gusella JF, MacDonald ME, Chen JF, Akbarian S, Weng Z, Vonsattel JP, Myers RH. miR-10b-5p expression in Huntington's disease brain relates to age of onset and the extent of striatal involvement. BMC Med Genomics. 2015; 8:10.View Related Profiles. PMID: 25889241; PMCID: PMC4349621; DOI: 10.1186/s12920-015-0083-3;
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Labadorf A, Hoss AG, Hadzi T, Myers RH. Immune Function and Neuro-inflammation are Implicated by mRNA Transcriptomics in Huntington Disease. Neurotherapeutics. 2015; 12(1):273.
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Hoss AG, Kartha VK, Labadorf A, Latourelle JC, Myers RH. microRNAs Expressed in Huntington Disease Brains Relate to Age of Onset and the Extent of Striatal Degeneration. Neurotherapeutics. 2015; 12(1):273.
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Correia K, Harold D, Kim KH, Holmans P, Jones L, Orth M, Myers RH, Kwak S, Wheeler VC, MacDonald ME, Gusella JF, Lee JM. The Genetic Modifiers of Motor OnsetAge (GeM MOA) Website: Genome-wide Association Analysis for Genetic Modifiers of Huntington's Disease. J Huntingtons Dis. 2015; 4(3):279-84. PMID: 26444025; PMCID: PMC4753529; DOI: 10.3233/JHD-150169;
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Bai G, Cheung I, Shulha HP, Coelho JE, Li P, Dong X, Jakovcevski M, Wang Y, Grigorenko A, Jiang Y, Hoss A, Patel K, Zheng M, Rogaev E, Myers RH, Weng Z, Akbarian S, Chen JF. Epigenetic dysregulation of hairy and enhancer of split 4 (HES4) is associated with striatal degeneration in postmortem Huntington brains. Hum Mol Genet. 2015 Mar 1; 24(5):1441-56.View Related Profiles. PMID: 25480889; PMCID: PMC4321450; DOI: 10.1093/hmg/ddu561;
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Bharadwaj R, Peter CJ, Jiang Y, Roussos P, Vogel-Ciernia A, Shen EY, Mitchell AC, Mao W, Whittle C, Dincer A, Jakovcevski M, Pothula V, Rasmussen TP, Giakoumaki SG, Bitsios P, Sherif A, Gardner PD, Ernst P, Ghose S, Sklar P, Haroutunian V, Tamminga C, Myers RH, Futai K, Wood MA, Akbarian S. Conserved higher-order chromatin regulates NMDA receptor gene expression and cognition. Neuron. 2014 Dec 3; 84(5):997-1008. PMID: 25467983; PMCID: PMC4258154; DOI: 10.1016/j.neuron.2014.10.032;
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Nalls MA, Pankratz N, Lill CM, Do CB, Hernandez DG, Saad M, DeStefano AL, Kara E, Bras J, Sharma M, Schulte C, Keller MF, Arepalli S, Letson C, Edsall C, Stefansson H, Liu X, Pliner H, Lee JH, Cheng R, Ikram MA, Ioannidis JP, Hadjigeorgiou GM, Bis JC, Martinez M, Perlmutter JS, Goate A, Marder K, Fiske B, Sutherland M, Xiromerisiou G, Myers RH, Clark LN, Stefansson K, Hardy JA, Heutink P, Chen H, Wood NW, Houlden H, Payami H, Brice A, Scott WK, Gasser T, Bertram L, Eriksson N, Foroud T, Singleton AB. Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease. Nat Genet. 2014 Sep; 46(9):989-93.View Related Profiles. PMID: 25064009; PMCID: PMC4146673; DOI: 10.1038/ng.3043;
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Hoss AG, Kartha VK, Dong X, Latourelle JC, Dumitriu A, Hadzi TC, Macdonald ME, Gusella JF, Akbarian S, Chen JF, Weng Z, Myers RH. MicroRNAs located in the Hox gene clusters are implicated in huntington's disease pathogenesis. PLoS Genet. 2014 Feb; 10(2):e1004188.View Related Profiles. PMID: 24586208; PMCID: PMC3937267; DOI: 10.1371/journal.pgen.1004188;
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Jones L, Gusella JF, MacDonald ME, Wheeler V, Lee JM, Myers RH, Latourelle JC, Harold D, Holmans P, Orth M, Kwak S. A03 Genetic Modifiers Affecting The Age At Motor Onset In Huntington's Disease. Journal of Neurology Neurosurgery & Psychiatry. 2014; 85(Suppl 1):A1-A2. View Publication
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Pichler I, Del Greco M F, Gögele M, Lill CM, Bertram L, Do CB, Eriksson N, Foroud T, Myers RH, Nalls M, Keller MF, Benyamin B, Whitfield JB, Pramstaller PP, Hicks AA, Thompson JR, Minelli C. Serum iron levels and the risk of Parkinson disease: a Mendelian randomization study. PLoS Med. 2013; 10(6):e1001462. PMID: 23750121; PMCID: PMC3672214; DOI: 10.1371/journal.pmed.1001462;
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Ramos EM, Latourelle JC, Gillis T, Mysore JS, Squitieri F, Di Pardo A, Di Donato S, Gellera C, Hayden MR, Morrison PJ, Nance M, Ross CA, Margolis RL, Gomez-Tortosa E, Ayuso C, Suchowersky O, Trent RJ, McCusker E, Novelletto A, Frontali M, Jones R, Ashizawa T, Frank S, Saint-Hilaire MH, Hersch SM, Rosas HD, Lucente D, Harrison MB, Zanko A, Abramson RK, Marder K, Gusella JF, Lee JM, Alonso I, Sequeiros J, Myers RH, Macdonald ME. Candidate glutamatergic and dopaminergic pathway gene variants do not influence Huntington's disease motor onset. Neurogenetics. 2013 Nov; 14(3-4):173-9.View Related Profiles. PMID: 23644918; PMCID: PMC3825533; DOI: 10.1007/s10048-013-0364-y;
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Dumitriu A, Myers RH, Mckee A, Seshadri S, Destefano A. RNA-sequencing evaluation of fresh frozen and formaldehyde-fixed prefrontal cortex brain tissue for the study of Alzheimer's disease. Alzheimer's and Dementia. 2013; 9(4):P177. View Publication
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Shulha HP, Crisci JL, Reshetov D, Tushir JS, Cheung I, Bharadwaj R, Chou HJ, Houston IB, Peter CJ, Mitchell AC, Yao WD, Myers RH, Chen JF, Preuss TM, Rogaev EI, Jensen JD, Weng Z, Akbarian S. Human-specific histone methylation signatures at transcription start sites in prefrontal neurons. PLoS Biol. 2012; 10(11):e1001427.View Related Profiles. PMID: 23185133; PMCID: PMC3502543; DOI: 10.1371/journal.pbio.1001427;
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Hadzi TC, Hendricks AE, Latourelle JC, Lunetta KL, Cupples LA, Gillis T, Mysore JS, Gusella JF, MacDonald ME, Myers RH, Vonsattel JP. Assessment of cortical and striatal involvement in 523 Huntington disease brains. Neurology. 2012 Oct 16; 79(16):1708-15.View Related Profiles. PMID: 23035064; PMCID: PMC3468776; DOI: 10.1212/WNL.0b013e31826e9a5d;
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Wilk JB, Shrine NR, Loehr LR, Zhao JH, Manichaikul A, Lopez LM, Smith AV, Heckbert SR, Smolonska J, Tang W, Loth DW, Curjuric I, Hui J, Cho MH, Latourelle JC, Henry AP, Aldrich M, Bakke P, Beaty TH, Bentley AR, Borecki IB, Brusselle GG, Burkart KM, Chen TH, Couper D, Crapo JD, Davies G, Dupuis J, Franceschini N, Gulsvik A, Hancock DB, Harris TB, Hofman A, Imboden M, James AL, Khaw KT, Lahousse L, Launer LJ, Litonjua A, Liu Y, Lohman KK, Lomas DA, Lumley T, Marciante KD, McArdle WL, Meibohm B, Morrison AC, Musk AW, Myers RH, North KE, Postma DS, Psaty BM, Rich SS, Rivadeneira F, Rochat T, Rotter JI, Artigas MS, Starr JM, Uitterlinden AG, Wareham NJ, Wijmenga C, Zanen P, Province MA, Silverman EK, Deary IJ, Palmer LJ, Cassano PA, Gudnason V, Barr RG, Loos RJ, Strachan DP, London SJ, Boezen HM, Probst-Hensch N, Gharib SA, Hall IP, O'Connor GT, Tobin MD, Stricker BH. Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction. Am J Respir Crit Care Med. 2012 Oct 1; 186(7):622-32.View Related Profiles. PMID: 22837378; PMCID: PMC3480517; DOI: 10.1164/rccm.201202-0366OC;
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Ramos EM, Latourelle JC, Lee JH, Gillis T, Mysore JS, Squitieri F, Di Pardo A, Di Donato S, Hayden MR, Morrison PJ, Nance M, Ross CA, Margolis RL, Gomez-Tortosa E, Ayuso C, Suchowersky O, Trent RJ, McCusker E, Novelletto A, Frontali M, Jones R, Ashizawa T, Frank S, Saint-Hilaire MH, Hersch SM, Rosas HD, Lucente D, Harrison MB, Zanko A, Marder K, Gusella JF, Lee JM, Alonso I, Sequeiros J, Myers RH, Macdonald ME. Population stratification may bias analysis of PGC-1a as a modifier of age at Huntington disease motor onset. Hum Genet. 2012 Dec; 131(12):1833-40.View Related Profiles. PMID: 22825315; PMCID: PMC3492689; DOI: 10.1007/s00439-012-1205-z;
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Lee JH, Lee JM, Ramos EM, Gillis T, Mysore JS, Kishikawa S, Hadzi T, Hendricks AE, Hayden MR, Morrison PJ, Nance M, Ross CA, Margolis RL, Squitieri F, Gellera C, Gomez-Tortosa E, Ayuso C, Suchowersky O, Trent RJ, McCusker E, Novelletto A, Frontali M, Jones R, Ashizawa T, Frank S, Saint-Hilaire MH, Hersch SM, Rosas HD, Lucente D, Harrison MB, Zanko A, Abramson RK, Marder K, Sequeiros J, Landwehrmeyer GB, Shoulson I, Myers RH, MacDonald ME, Gusella JF. TAA repeat variation in the GRIK2 gene does not influence age at onset in Huntington's disease. Biochem Biophys Res Commun. 2012 Aug 3; 424(3):404-8.View Related Profiles. PMID: 22771793; PMCID: PMC3752397; DOI: 10.1016/j.bbrc.2012.06.120;
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Dumitriu A, Latourelle JC, Hadzi TC, Pankratz N, Garza D, Miller JP, Vance JM, Foroud T, Beach TG, Myers RH. Gene expression profiles in Parkinson disease prefrontal cortex implicate FOXO1 and genes under its transcriptional regulation. PLoS Genet. 2012 Jun; 8(6):e1002794.View Related Profiles. PMID: 22761592; PMCID: PMC3386245; DOI: 10.1371/journal.pgen.1002794;
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Lill CM, Roehr JT, McQueen MB, Kavvoura FK, Bagade S, Schjeide BM, Schjeide LM, Meissner E, Zauft U, Allen NC, Liu T, Schilling M, Anderson KJ, Beecham G, Berg D, Biernacka JM, Brice A, DeStefano AL, Do CB, Eriksson N, Factor SA, Farrer MJ, Foroud T, Gasser T, Hamza T, Hardy JA, Heutink P, Hill-Burns EM, Klein C, Latourelle JC, Maraganore DM, Martin ER, Martinez M, Myers RH, Nalls MA, Pankratz N, Payami H, Satake W, Scott WK, Sharma M, Singleton AB, Stefansson K, Toda T, Tung JY, Vance J, Wood NW, Zabetian CP, Young P, Tanzi RE, Khoury MJ, Zipp F, Lehrach H, Ioannidis JP, Bertram L. Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database. PLoS Genet. 2012; 8(3):e1002548.View Related Profiles. PMID: 22438815; PMCID: PMC3305333; DOI: 10.1371/journal.pgen.1002548;
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Dumitriu A, Moser C, Hadzi TC, Williamson SL, Pacheco CD, Hendricks AE, Latourelle JC, Wilk JB, Destefano AL, Myers RH. Postmortem Interval Influences a-Synuclein Expression in Parkinson Disease Brain. Parkinsons Dis. 2012; 2012:614212.View Related Profiles. PMID: 22530163; PMCID: PMC3317023; DOI: 10.1155/2012/614212;
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Lee JM, Gillis T, Mysore JS, Ramos EM, Myers RH, Hayden MR, Morrison PJ, Nance M, Ross CA, Margolis RL, Squitieri F, Griguoli A, Di Donato S, Gomez-Tortosa E, Ayuso C, Suchowersky O, Trent RJ, McCusker E, Novelletto A, Frontali M, Jones R, Ashizawa T, Frank S, Saint-Hilaire MH, Hersch SM, Rosas HD, Lucente D, Harrison MB, Zanko A, Abramson RK, Marder K, Sequeiros J, MacDonald ME, Gusella JF. Common SNP-based haplotype analysis of the 4p16.3 Huntington disease gene region. Am J Hum Genet. 2012 Mar 9; 90(3):434-44.View Related Profiles. PMID: 22387017; PMCID: PMC3309179; DOI: 10.1016/j.ajhg.2012.01.005;
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Pankratz N, Beecham GW, DeStefano AL, Dawson TM, Doheny KF, Factor SA, Hamza TH, Hung AY, Hyman BT, Ivinson AJ, Krainc D, Latourelle JC, Clark LN, Marder K, Martin ER, Mayeux R, Ross OA, Scherzer CR, Simon DK, Tanner C, Vance JM, Wszolek ZK, Zabetian CP, Myers RH, Payami H, Scott WK, Foroud T. Meta-analysis of Parkinson's disease: identification of a novel locus, RIT2. Ann Neurol. 2012 Mar; 71(3):370-84.View Related Profiles. PMID: 22451204; PMCID: PMC3354734; DOI: 10.1002/ana.22687;
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Lee JM, Ramos EM, Lee JH, Gillis T, Mysore JS, Hayden MR, Warby SC, Morrison P, Nance M, Ross CA, Margolis RL, Squitieri F, Orobello S, Di Donato S, Gomez-Tortosa E, Ayuso C, Suchowersky O, Trent RJ, McCusker E, Novelletto A, Frontali M, Jones R, Ashizawa T, Frank S, Saint-Hilaire MH, Hersch SM, Rosas HD, Lucente D, Harrison MB, Zanko A, Abramson RK, Marder K, Sequeiros J, Paulsen JS, Landwehrmeyer GB, Myers RH, MacDonald ME, Gusella JF. CAG repeat expansion in Huntington disease determines age at onset in a fully dominant fashion. Neurology. 2012 Mar 6; 78(10):690-5.View Related Profiles. PMID: 22323755; PMCID: PMC3306163; DOI: 10.1212/WNL.0b013e318249f683;
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Sebastiani P, Solovieff N, Dewan AT, Walsh KM, Puca A, Hartley SW, Melista E, Andersen S, Dworkis DA, Wilk JB, Myers RH, Steinberg MH, Montano M, Baldwin CT, Hoh J, Perls TT. Genetic signatures of exceptional longevity in humans. PLoS One. 2012; 7(1):e29848.View Related Profiles. PMID: 22279548; PMCID: PMC3261167; DOI: 10.1371/journal.pone.0029848;
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Ehret GB, Munroe PB, Rice KM, Bochud M, Johnson AD, Chasman DI, Smith AV, Tobin MD, Verwoert GC, Hwang SJ, Pihur V, Vollenweider P, O'Reilly PF, Amin N, Bragg-Gresham JL, Teumer A, Glazer NL, Launer L, Zhao JH, Aulchenko Y, Heath S, Sõber S, Parsa A, Luan J, Arora P, Dehghan A, Zhang F, Lucas G, Hicks AA, Jackson AU, Peden JF, Tanaka T, Wild SH, Rudan I, Igl W, Milaneschi Y, Parker AN, Fava C, Chambers JC, Fox ER, Kumari M, Go MJ, van der Harst P, Kao WH, Sjögren M, Vinay DG, Alexander M, Tabara Y, Shaw-Hawkins S, Whincup PH, Liu Y, Shi G, Kuusisto J, Tayo B, Seielstad M, Sim X, Nguyen KD, Lehtimäki T, Matullo G, Wu Y, Gaunt TR, Onland-Moret NC, Cooper MN, Platou CG, Org E, Hardy R, Dahgam S, Palmen J, Vitart V, Braund PS, Kuznetsova T, Uiterwaal CS, Adeyemo A, Palmas W, Campbell H, Ludwig B, Tomaszewski M, Tzoulaki I, Palmer ND, Aspelund T, Garcia M, Chang YP, O'Connell JR, Steinle NI, Grobbee DE, Arking DE, Kardia SL, Morrison AC, Hernandez D, Najjar S, McArdle WL, Hadley D, Brown MJ, Connell JM, Hingorani AD, Day IN, Lawlor DA, Beilby JP, Lawrence RW, Clarke R, Hopewell JC, Ongen H, Dreisbach AW, Li Y, Young JH, Bis JC, Kähönen M, Viikari J, Adair LS, Lee NR, Chen MH, Olden M, Pattaro C, Bolton JA, Köttgen A, Bergmann S, Mooser V, Chaturvedi N, Frayling TM, Islam M, Jafar TH, Erdmann J, Kulkarni SR, Bornstein SR, Grässler J, Groop L, Voight BF, Kettunen J, Howard P, Taylor A, Guarrera S, Ricceri F, Emilsson V, Plump A, Barroso I, Khaw KT, Weder AB, Hunt SC, Sun YV, Bergman RN, Collins FS, Bonnycastle LL, Scott LJ, Stringham HM, Peltonen L, Perola M, Vartiainen E, Brand SM, Staessen JA, Wang TJ, Burton PR, Soler Artigas M, Dong Y, Snieder H, Wang X, Zhu H, Lohman KK, Rudock ME, Heckbert SR, Smith NL, Wiggins KL, Doumatey A, Shriner D, Veldre G, Viigimaa M, Kinra S, Prabhakaran D, Tripathy V, Langefeld CD, Rosengren A, Thelle DS, Corsi AM, Singleton A, Forrester T, Hilton G, McKenzie CA, Salako T, Iwai N, Kita Y, Ogihara T, Ohkubo T, Okamura T, Ueshima H, Umemura S, Eyheramendy S, Meitinger T, Wichmann HE, Cho YS, Kim HL, Lee JY, Scott J, Sehmi JS, Zhang W, Hedblad B, Nilsson P, Smith GD, Wong A, Narisu N, Stancáková A, Raffel LJ, Yao J, Kathiresan S, O'Donnell CJ, Schwartz SM, Ikram MA, Longstreth WT, Mosley TH, Seshadri S, Shrine NR, Wain LV, Morken MA, Swift AJ, Laitinen J, Prokopenko I, Zitting P, Cooper JA, Humphries SE, Danesh J, Rasheed A, Goel A, Hamsten A, Watkins H, Bakker SJ, van Gilst WH, Janipalli CS, Mani KR, Yajnik CS, Hofman A, Mattace-Raso FU, Oostra BA, Demirkan A, Isaacs A, Rivadeneira F, Lakatta EG, Orru M, Scuteri A, Ala-Korpela M, Kangas AJ, Lyytikäinen LP, Soininen P, Tukiainen T, Würtz P, Ong RT, Dörr M, Kroemer HK, Völker U, Völzke H, Galan P, Hercberg S, Lathrop M, Zelenika D, Deloukas P, Mangino M, Spector TD, Zhai G, Meschia JF, Nalls MA, Sharma P, Terzic J, Kumar MV, Denniff M, Zukowska-Szczechowska E, Wagenknecht LE, Fowkes FG, Charchar FJ, Schwarz PE, Hayward C, Guo X, Rotimi C, Bots ML, Brand E, Samani NJ, Polasek O, Talmud PJ, Nyberg F, Kuh D, Laan M, Hveem K, Palmer LJ, van der Schouw YT, Casas JP, Mohlke KL, Vineis P, Raitakari O, Ganesh SK, Wong TY, Tai ES, Cooper RS, Laakso M, Rao DC, Harris TB, Morris RW, Dominiczak AF, Kivimaki M, Marmot MG, Miki T, Saleheen D, Chandak GR, Coresh J, Navis G, Salomaa V, Han BG, Zhu X, Kooner JS, Melander O, Ridker PM, Bandinelli S, Gyllensten UB, Wright AF, Wilson JF, Ferrucci L, Farrall M, Tuomilehto J, Pramstaller PP, Elosua R, Soranzo N, Sijbrands EJ, Altshuler D, Loos RJ, Shuldiner AR, Gieger C, Meneton P, Uitterlinden AG, Wareham NJ, Gudnason V, Rotter JI, Rettig R, Uda M, Strachan DP, Witteman JC, Hartikainen AL, Beckmann JS, Boerwinkle E, Vasan RS, Boehnke M, Larson MG, Järvelin MR, Psaty BM, Abecasis GR, Chakravarti A, Elliott P, van Duijn CM, Newton-Cheh C, Levy D, Caulfield MJ, Johnson T. Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature. 2011 Oct 6; 478(7367):103-9.View Related Profiles. PMID: 21909115; PMCID: PMC3340926; DOI: 10.1038/nature10405;
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Pankratz N, Dumitriu A, Hetrick KN, Sun M, Latourelle JC, Wilk JB, Halter C, Doheny KF, Gusella JF, Nichols WC, Myers RH, Foroud T, DeStefano AL. Copy number variation in familial Parkinson disease. PLoS One. 2011; 6(8):e20988.View Related Profiles. PMID: 21829596; PMCID: PMC3149037; DOI: 10.1371/journal.pone.0020988;
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Sebastiani P, Solovieff N, Puca A, Hartley SW, Melista E, Andersen S, Dworkis DA, Wilk JB, Myers RH, Steinberg MH, Montano M, Baldwin CT, Perls TT. Retraction. Science. 2011 Jul 22; 333(6041):404.View Related Profiles. PMID: 21778381; DOI: 10.1126/science.333.6041.404-a;
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Soldner F, Laganière J, Cheng AW, Hockemeyer D, Gao Q, Alagappan R, Khurana V, Golbe LI, Myers RH, Lindquist S, Zhang L, Guschin D, Fong LK, Vu BJ, Meng X, Urnov FD, Rebar EJ, Gregory PD, Zhang HS, Jaenisch R. Generation of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutations. Cell. 2011 Jul 22; 146(2):318-31. PMID: 21757228; PMCID: PMC3155290; DOI: 10.1016/j.cell.2011.06.019;
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Latourelle JC, Hendricks AE, Pankratz N, Wilk JB, Halter C, Nichols WC, Gusella JF, Destefano AL, Myers RH, Foroud T. Genomewide linkage study of modifiers of LRRK2-related Parkinson's disease. Mov Disord. 2011 Sep; 26(11):2039-44.View Related Profiles. PMID: 21661047; PMCID: PMC3346677; DOI: 10.1002/mds.23781;
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Dumitriu A, Pacheco CD, Wilk JB, Strathearn KE, Latourelle JC, Goldwurm S, Pezzoli G, Rochet JC, Lindquist S, Myers RH. Cyclin-G-associated kinase modifies a-synuclein expression levels and toxicity in Parkinson's disease: results from the GenePD Study. Hum Mol Genet. 2011 Apr 15; 20(8):1478-87.View Related Profiles. PMID: 21258085; PMCID: PMC3063983; DOI: 10.1093/hmg/ddr026;
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Sebastiani P, Solovieff N, Puca A, Perls T, Myers RH et. al. Editorial Expression of Concern (Retraction of vol 330, pg 912, 2010). Science. 2011; 333(6041):404.
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Speliotes EK, Willer CJ, Berndt SI, Monda KL, Thorleifsson G, Jackson AU, Lango Allen H, Lindgren CM, Luan J, Mägi R, Randall JC, Vedantam S, Winkler TW, Qi L, Workalemahu T, Heid IM, Steinthorsdottir V, Stringham HM, Weedon MN, Wheeler E, Wood AR, Ferreira T, Weyant RJ, Segrè AV, Estrada K, Liang L, Nemesh J, Park JH, Gustafsson S, Kilpeläinen TO, Yang J, Bouatia-Naji N, Esko T, Feitosa MF, Kutalik Z, Mangino M, Raychaudhuri S, Scherag A, Smith AV, Welch R, Zhao JH, Aben KK, Absher DM, Amin N, Dixon AL, Fisher E, Glazer NL, Goddard ME, Heard-Costa NL, Hoesel V, Hottenga JJ, Johansson A, Johnson T, Ketkar S, Lamina C, Li S, Moffatt MF, Myers RH, Narisu N, Perry JR, Peters MJ, Preuss M, Ripatti S, Rivadeneira F, Sandholt C, Scott LJ, Timpson NJ, Tyrer JP, van Wingerden S, Watanabe RM, White CC, Wiklund F, Barlassina C, Chasman DI, Cooper MN, Jansson JO, Lawrence RW, Pellikka N, Prokopenko I, Shi J, Thiering E, Alavere H, Alibrandi MT, Almgren P, Arnold AM, Aspelund T, Atwood LD, Balkau B, Balmforth AJ, Bennett AJ, Ben-Shlomo Y, Bergman RN, Bergmann S, Biebermann H, Blakemore AI, Boes T, Bonnycastle LL, Bornstein SR, Brown MJ, Buchanan TA, Busonero F, Campbell H, Cappuccio FP, Cavalcanti-Proença C, Chen YD, Chen CM, Chines PS, Clarke R, Coin L, Connell J, Day IN, den Heijer M, Duan J, Ebrahim S, Elliott P, Elosua R, Eiriksdottir G, Erdos MR, Eriksson JG, Facheris MF, Felix SB, Fischer-Posovszky P, Folsom AR, Friedrich N, Freimer NB, Fu M, Gaget S, Gejman PV, Geus EJ, Gieger C, Gjesing AP, Goel A, Goyette P, Grallert H, Grässler J, Greenawalt DM, Groves CJ, Gudnason V, Guiducci C, Hartikainen AL, Hassanali N, Hall AS, Havulinna AS, Hayward C, Heath AC, Hengstenberg C, Hicks AA, Hinney A, Hofman A, Homuth G, Hui J, Igl W, Iribarren C, Isomaa B, Jacobs KB, Jarick I, Jewell E, John U, Jørgensen T, Jousilahti P, Jula A, Kaakinen M, Kajantie E, Kaplan LM, Kathiresan S, Kettunen J, Kinnunen L, Knowles JW, Kolcic I, König IR, Koskinen S, Kovacs P, Kuusisto J, Kraft P, Kvaløy K, Laitinen J, Lantieri O, Lanzani C, Launer LJ, Lecoeur C, Lehtimäki T, Lettre G, Liu J, Lokki ML, Lorentzon M, Luben RN, Ludwig B, Manunta P, Marek D, Marre M, Martin NG, McArdle WL, McCarthy A, McKnight B, Meitinger T, Melander O, Meyre D, Midthjell K, Montgomery GW, Morken MA, Morris AP, Mulic R, Ngwa JS, Nelis M, Neville MJ, Nyholt DR, O'Donnell CJ, O'Rahilly S, Ong KK, Oostra B, Paré G, Parker AN, Perola M, Pichler I, Pietiläinen KH, Platou CG, Polasek O, Pouta A, Rafelt S, Raitakari O, Rayner NW, Ridderstråle M, Rief W, Ruokonen A, Robertson NR, Rzehak P, Salomaa V, Sanders AR, Sandhu MS, Sanna S, Saramies J, Savolainen MJ, Scherag S, Schipf S, Schreiber S, Schunkert H, Silander K, Sinisalo J, Siscovick DS, Smit JH, Soranzo N, Sovio U, Stephens J, Surakka I, Swift AJ, Tammesoo ML, Tardif JC, Teder-Laving M, Teslovich TM, Thompson JR, Thomson B, Tönjes A, Tuomi T, van Meurs JB, van Ommen GJ, Vatin V, Viikari J, Visvikis-Siest S, Vitart V, Vogel CI, Voight BF, Waite LL, Wallaschofski H, Walters GB, Widen E, Wiegand S, Wild SH, Willemsen G, Witte DR, Witteman JC, Xu J, Zhang Q, Zgaga L, Ziegler A, Zitting P, Beilby JP, Farooqi IS, Hebebrand J, Huikuri HV, James AL, Kähönen M, Levinson DF, Macciardi F, Nieminen MS, Ohlsson C, Palmer LJ, Ridker PM, Stumvoll M, Beckmann JS, Boeing H, Boerwinkle E, Boomsma DI, Caulfield MJ, Chanock SJ, Collins FS, Cupples LA, Smith GD, Erdmann J, Froguel P, Grönberg H, Gyllensten U, Hall P, Hansen T, Harris TB, Hattersley AT, Hayes RB, Heinrich J, Hu FB, Hveem K, Illig T, Jarvelin MR, Kaprio J, Karpe F, Khaw KT, Kiemeney LA, Krude H, Laakso M, Lawlor DA, Metspalu A, Munroe PB, Ouwehand WH, Pedersen O, Penninx BW, Peters A, Pramstaller PP, Quertermous T, Reinehr T, Rissanen A, Rudan I, Samani NJ, Schwarz PE, Shuldiner AR, Spector TD, Tuomilehto J, Uda M, Uitterlinden A, Valle TT, Wabitsch M, Waeber G, Wareham NJ, Watkins H, Wilson JF, Wright AF, Zillikens MC, Chatterjee N, McCarroll SA, Purcell S, Schadt EE, Visscher PM, et al. AssocView Related Profiles. PMID: 20935630; PMCID: PMC3014648; DOI: 10.1038/ng.686;
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Sebastiani P, Solovieff N, Puca A, Hartley SW, Melista E, Andersen S, Dworkis DA, Wilk JB, Myers RH, Steinberg MH, Montano M, Baldwin CT, Perls TT. Genetic signatures of exceptional longevity in humans. Science. 2010 Jul 1; 2010.View Related Profiles. PMID: 20595579; DOI: 10.1126/science.1190532;
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Hendricks A, Myers RH, Lunetta K. Retaining Power: Is it Possible to Simply and Effectively Adjust for Multiple Comparisons in a Candidate Gene Region?. 19th Annual Meeting of the International-Genetic-Epidemiology-Society. 2010; 34.
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Latourelle JC, Pankratz N, Dumitriu A, Wilk JB, Goldwurm S, Pezzoli G, Mariani CB, DeStefano AL, Halter C, Gusella JF, Nichols WC, Myers RH, Foroud T. Genomewide association study for onset age in Parkinson disease. BMC Med Genet. 2009; 10:98.View Related Profiles. PMID: 19772629; PMCID: PMC2758866; DOI: 10.1186/1471-2350-10-98;
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Hendricks AE, Latourelle JC, Lunetta KL, Cupples LA, Wheeler V, MacDonald ME, Gusella JF, Myers RH. Estimating the probability of de novo HD cases from transmissions of expanded penetrant CAG alleles in the Huntington disease gene from male carriers of high normal alleles (27-35 CAG). Am J Med Genet A. 2009 Jul; 149A(7):1375-81.View Related Profiles. PMID: 19507258; PMCID: PMC2724761; DOI: 10.1002/ajmg.a.32901;
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Feitosa MF, North KE, Myers RH, Pankow JS, Borecki IB. Evidence for three novel QTLs for adiposity on chromosome 2 with epistatic interactions: the NHLBI Family Heart Study. Obesity (Silver Spring). 2009 Dec; 17(12):2190-5. PMID: 19521348; PMCID: PMC4976636; DOI: 10.1038/oby.2009.181;
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Swami M, Hendricks AE, Gillis T, Massood T, Mysore J, Myers RH, Wheeler VC. Somatic expansion of the Huntington's disease CAG repeat in the brain is associated with an earlier age of disease onset. Hum Mol Genet. 2009 Aug 15; 18(16):3039-47. PMID: 19465745; PMCID: PMC2714728; DOI: 10.1093/hmg/ddp242;
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Laramie JM, Wilk JB, Williamson SL, Nagle MW, Latourelle JC, Tobin JE, Province MA, Borecki IB, Myers RH. Multiple genes influence BMI on chromosome 7q31-34: the NHLBI Family Heart Study. Obesity (Silver Spring). 2009 Dec; 17(12):2182-9.View Related Profiles. PMID: 19461589; DOI: 10.1038/oby.2009.141;
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Wilk JB, Chen TH, Gottlieb DJ, Walter RE, Nagle MW, Brandler BJ, Myers RH, Borecki IB, Silverman EK, Weiss ST, O'Connor GT. A genome-wide association study of pulmonary function measures in the Framingham Heart Study. PLoS Genet. 2009 Mar; 5(3):e1000429.View Related Profiles. PMID: 19300500; PMCID: PMC2652834; DOI: 10.1371/journal.pgen.1000429;
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Franceschini N, North KE, Arnett D, Pankow JS, Chung JH, Baird L, Leppert MF, Eckfeldt JH, Boerwinkle E, Gu CC, Lewis CE, Myers RH, Turner ST, Weder A, Kao WH, Mosley TH, Chakravarti A, Kramer H, Zhang J, Hunt SC. The association of cell cycle checkpoint 2 variants and kidney function: findings of the Family Blood Pressure Program and the Atherosclerosis Risk In Communities study. Am J Hypertens. 2009 May; 22(5):552-8. PMID: 19265784; PMCID: PMC2727134; DOI: 10.1038/ajh.2009.41;
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Ma D, Feitosa MF, Wilk JB, Laramie JM, Yu K, Leiendecker-Foster C, Myers RH, Province MA, Borecki IB. Leptin is associated with blood pressure and hypertension in women from the National Heart, Lung, and Blood Institute Family Heart Study. Hypertension. 2009 Mar; 53(3):473-9. PMID: 19204185; PMCID: PMC2668693; DOI: 10.1161/HYPERTENSIONAHA.108.118133;
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Latourelle JC, Hendricks A, Wilk JB, DeStefano AL, Pankratz N, Foroud T, Myers RH. Rare Variants with Recessive Effects identified in a Genome-wide Association Study of Parkinson's Disease. 18th Annual Meeting of the International-Genetic-Epidemiology-Society. 2009.
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Wu J, Pankow JS, Tracy RP, North KE, Myers RH, Feitosa ME, Province MA, Borecki IB. A QTL on 12q influencing an inflammation marker and obesity in white women: the NHLBI Family Heart Study. Obesity (Silver Spring). 2009 Mar; 17(3):525-31. PMID: 19238141; PMCID: PMC4962615; DOI: 10.1038/oby.2008.556;
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Shi G, Gu CC, Kraja AT, Arnett DK, Myers RH, Pankow JS, Hunt SC, Rao DC. Genetic effect on blood pressure is modulated by age: the Hypertension Genetic Epidemiology Network Study. Hypertension. 2009 Jan; 53(1):35-41. PMID: 19029486; PMCID: PMC2633773; DOI: 10.1161/HYPERTENSIONAHA.108.120071;
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Pankratz N, Wilk JB, Latourelle JC, DeStefano AL, Halter C, Pugh EW, Doheny KF, Gusella JF, Nichols WC, Foroud T, Myers RH. Genomewide association study for susceptibility genes contributing to familial Parkinson disease. Hum Genet. 2009 Jan; 124(6):593-605.View Related Profiles. PMID: 18985386; PMCID: PMC2627511; DOI: 10.1007/s00439-008-0582-9;
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Latourelle JC, Sun M, Lew MF, Suchowersky O, Klein C, Golbe LI, Mark MH, Growdon JH, Wooten GF, Watts RL, Guttman M, Racette BA, Perlmutter JS, Ahmed A, Shill HA, Singer C, Goldwurm S, Pezzoli G, Zini M, Saint-Hilaire MH, Hendricks AE, Williamson S, Nagle MW, Wilk JB, Massood T, Huskey KW, Laramie JM, DeStefano AL, Baker KB, Itin I, Litvan I, Nicholson G, Corbett A, Nance M, Drasby E, Isaacson S, Burn DJ, Chinnery PF, Pramstaller PP, Al-hinti J, Moller AT, Ostergaard K, Sherman SJ, Roxburgh R, Snow B, Slevin JT, Cambi F, Gusella JF, Myers RH. The Gly2019Ser mutation in LRRK2 is not fully penetrant in familial Parkinson's disease: the GenePD study. BMC Med. 2008; 6:32.View Related Profiles. PMID: 18986508; PMCID: PMC2596771; DOI: 10.1186/1741-7015-6-32;
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McNicoll CF, Latourelle JC, MacDonald ME, Lew MF, Suchowersky O, Klein C, Golbe LI, Mark MH, Growdon JH, Wooten GF, Watts RL, Guttman M, Racette BA, Perlmutter JS, Ahmed A, Shill HA, Singer C, Saint-Hilaire MH, Massood T, Huskey KW, DeStefano AL, Gillis T, Mysore J, Goldwurm S, Pezzoli G, Baker KB, Itin I, Litvan I, Nicholson G, Corbett A, Nance M, Drasby E, Isaacson S, Burn DJ, Chinnery PF, Pramstaller PP, Al-Hinti J, Moller AT, Ostergaard K, Sherman SJ, Roxburgh R, Snow B, Slevin JT, Cambi F, Gusella JF, Myers RH. Huntington CAG repeat size does not modify onset age in familial Parkinson's disease: the GenePD study. Mov Disord. 2008 Aug 15; 23(11):1596-601.View Related Profiles. PMID: 18649400; PMCID: PMC2655323; DOI: 10.1002/mds.22186;
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DeStefano AL, Latourelle J, Lew MF, Suchowersky O, Klein C, Golbe LI, Mark MH, Growdon JH, Wooten GF, Watts R, Guttman M, Racette BA, Perlmutter JS, Marlor L, Shill HA, Singer C, Goldwurm S, Pezzoli G, Saint-Hilaire MH, Hendricks AE, Gower A, Williamson S, Nagle MW, Wilk JB, Massood T, Huskey KW, Baker KB, Itin I, Litvan I, Nicholson G, Corbett A, Nance M, Drasby E, Isaacson S, Burn DJ, Chinnery PF, Pramstaller PP, Al-Hinti J, Moller AT, Ostergaard K, Sherman SJ, Roxburgh R, Snow B, Slevin JT, Cambi F, Gusella JF, Myers RH. Replication of association between ELAVL4 and Parkinson disease: the GenePD study. Hum Genet. 2008 Aug; 124(1):95-9.View Related Profiles. PMID: 18587682; PMCID: PMC2716559; DOI: 10.1007/s00439-008-0526-4;
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Tobin JE, Latourelle JC, Lew MF, Klein C, Suchowersky O, Shill HA, Golbe LI, Mark MH, Growdon JH, Wooten GF, Racette BA, Perlmutter JS, Watts R, Guttman M, Baker KB, Goldwurm S, Pezzoli G, Singer C, Saint-Hilaire MH, Hendricks AE, Williamson S, Nagle MW, Wilk JB, Massood T, Laramie JM, DeStefano AL, Litvan I, Nicholson G, Corbett A, Isaacson S, Burn DJ, Chinnery PF, Pramstaller PP, Sherman S, Al-hinti J, Drasby E, Nance M, Moller AT, Ostergaard K, Roxburgh R, Snow B, Slevin JT, Cambi F, Gusella JF, Myers RH. Haplotypes and gene expression implicate the MAPT region for Parkinson disease: the GenePD Study. Neurology. 2008 Jul 1; 71(1):28-34.View Related Profiles. PMID: 18509094; PMCID: PMC2654275; DOI: 10.1212/01.wnl.0000304051.01650.23;
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Laramie JM, Wilk JB, Williamson SL, Nagle MW, Latourelle JC, Tobin JE, Province MA, Borecki IB, Myers RH. Polymorphisms near EXOC4 and LRGUK on chromosome 7q32 are associated with Type 2 Diabetes and fasting glucose; the NHLBI Family Heart Study. BMC Med Genet. 2008; 9:46.View Related Profiles. PMID: 18498660; PMCID: PMC2409301; DOI: 10.1186/1471-2350-9-46;
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Zhang Q, Lewis CE, Wagenknecht LE, Myers RH, Pankow JS, Hunt SC, North KE, Hixson JE, Jeffrey Carr J, Shimmin LC, Borecki I, Province MA. Genome-wide admixture mapping for coronary artery calcification in African Americans: the NHLBI Family Heart Study. Genet Epidemiol. 2008 Apr; 32(3):264-72. PMID: 18200599; DOI: 10.1002/gepi.20301;
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Wilk JB, Laramie JM, Latourelle JC, Williamson S, Nagle MW, Tobin JE, Foster CL, Eckfeldt JH, Province MA, Borecki IB, Myers RH. NYD-SP18 is associated with obesity in the NHLBI Family Heart Study. Int J Obes (Lond). 2008 Jun; 32(6):930-5.View Related Profiles. PMID: 18317470; PMCID: PMC2667232; DOI: 10.1038/ijo.2008.23;
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Massood T, Latourelle JC, Srinidhi Mysore J, Fossale E, Gillis T, Gusella JF, MacDonald ME, Myers RH. HD Repeat Determines the Rate of Neuropathological Change. Neurotherapeutics. 2008; 5(2):367. View Publication
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Moser K, Biglan K, Ross CA, EHDN Working Group 'Symptomatic Treatment'. Inaugural Huntington Disease Clinical Research Symposium Organized by the Huntington Study Group. Neurotherapeutics. 2008; 5(2):363-375. View Publication
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Shi G, Gu CC, Kraja AT, Arnett DK, Myers RH, Pankow JS, Hunt SC, Thirupathi Rao DC. Modeling Age Variation in QTL Effects Leads to Substantially Improved Linkage Evidence for Blood Pressure in the HyperGEN Study. 17th Annual Meeting of the International-Genetic-Epidemiology-Society. 2008.
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Feitosa MF, An P, Ketkar S, Myers RH, Pankow JS, Province M, Borecki I. Association of promoter LIPC variants with fat distribution and HDL level: The NHLBI Family Heart Study (FHS). 17th Annual Meeting of the International-Genetic-Epidemiology-Society. 2008.
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Bielinski SJ, Pankow JS, Foster CL, Miller MB, Hopkins PN, Eckfeldt JH, Hixson J, Liu Y, Register T, Myers RH, Arnett DK. Circulating soluble ICAM-1 levels shows linkage to ICAM gene cluster region on chromosome 19: the NHLBI Family Heart Study follow-up examination. Atherosclerosis. 2008 Jul; 199(1):172-8. PMID: 18045607; PMCID: PMC2517220; DOI: 10.1016/j.atherosclerosis.2007.10.006;
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Bielinski SJ, Pankow JS, Miller MB, Hopkins PN, Eckfeldt JH, Hixson J, Liu Y, Register T, Myers RH, Arnett DK. Circulating MCP-1 levels shows linkage to chemokine receptor gene cluster on chromosome 3: the NHLBI family heart study follow-up examination. Genes Immun. 2007 Dec; 8(8):684-90. PMID: 17917677
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Dupré N, Rivière JB, Myers RH, Provencher P, Pourcher E, Emond F, Rouleau GA. LRRK2 is not a significant cause of Parkinson's disease in French-Canadians. Can J Neurol Sci. 2007 Aug; 34(3):333-5. PMID: 17803032
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Wheeler VC, Persichetti F, McNeil SM, Mysore JS, Mysore SS, MacDonald ME, Myers RH, Gusella JF, Wexler NS. Factors associated with HD CAG repeat instability in Huntington disease. J Med Genet. 2007 Nov; 44(11):695-701. PMID: 17660463; PMCID: PMC2705129; DOI: 10.1136/jmg.2007.050930;
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Litvan I, Chesselet MF, Gasser T, Di Monte DA, Parker D, Hagg T, Hardy J, Jenner P, Myers RH, Price D, Hallett M, Langston WJ, Lang AE, Halliday G, Rocca W, Duyckaerts C, Dickson DW, Ben-Shlomo Y, Goetz CG, Melamed E. The etiopathogenesis of Parkinson disease and suggestions for future research. Part II. J Neuropathol Exp Neurol. 2007 May; 66(5):329-36. PMID: 17483689
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Litvan I, Halliday G, Hallett M, Goetz CG, Rocca W, Duyckaerts C, Ben-Shlomo Y, Dickson DW, Lang AE, Chesselet MF, Langston WJ, Di Monte DA, Gasser T, Hagg T, Hardy J, Jenner P, Melamed E, Myers RH, Parker D, Price DL. The etiopathogenesis of Parkinson disease and suggestions for future research. Part I. J Neuropathol Exp Neurol. 2007 Apr; 66(4):251-7. PMID: 17413315
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Greenwood TA, Libiger O, Kardia S, Hanis C, Morrison AC, Gu CC, Rice T, Miller M, Turner ST, Myers RH, Grove J, Hsiao CF, Weder AB, Schork NJ. Comprehensive linkage and linkage heterogeneity analysis of 4344 sibling pairs affected with hypertension from the Family Blood Pressure Program. Genet Epidemiol. 2007 Apr; 31(3):195-210. PMID: 17266112
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Borecki I, Feitosa MF, Ma D, North KE, Williamson S, Laramie J, Myers RH. The general transcription factor FOXO1A on 13q14 is associated with obesity. 15th Annual Meeting of the International-Genetic-Epidemiology-Society. 2007; 31.
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Feitosa MF, North K, Myers RH, Pankow JS, Borecki I. Lipid and dietary factors confound detection of a QTL on 2p24-p25 for adiposity: the NHLBI-Family Heart Study. 15th Annual Meeting of the International-Genetic-Epidemiology-Society. 2007; 31.
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Feitosa MF, Myers RH, Province M, Borecki I. Genetic variation in the hepatic lipase gene is associated with HDL-cholesterol levels in the NHLB Family Heart Study. 16th Annual Meeting of the International-Genetic-Epidemiology-Society. 2007; 31.
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North KE, Franceschini N, Borecki IB, Gu CC, Heiss G, Province MA, Arnett DK, Lewis CE, Miller MB, Myers RH, Hunt SC, Freedman BI. Genotype-by-sex interaction on fasting insulin concentration: the HyperGEN study. Diabetes. 2007 Jan; 56(1):137-42. PMID: 17192475
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Wilk JB, Tobin JE, Suchowersky O, Shill HA, Klein C, Wooten GF, Lew MF, Mark MH, Guttman M, Watts RL, Singer C, Growdon JH, Latourelle JC, Saint-Hilaire MH, DeStefano AL, Prakash R, Williamson S, Berg CJ, Sun M, Goldwurm S, Pezzoli G, Racette BA, Perlmutter JS, Parsian A, Baker KB, Giroux ML, Litvan I, Pramstaller PP, Nicholson G, Burn DJ, Chinnery PF, Vieregge P, Slevin JT, Cambi F, MacDonald ME, Gusella JF, Myers RH, Golbe LI. Herbicide exposure modifies GSTP1 haplotype association to Parkinson onset age: the GenePD Study. Neurology. 2006 Dec 26; 67(12):2206-10.View Related Profiles. PMID: 17190945
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Andresen JM, Gayán J, Djoussé L, Roberts S, Brocklebank D, Cherny SS, Cardon LR, Gusella JF, MacDonald ME, Myers RH, Housman DE, Wexler NS. The relationship between CAG repeat length and age of onset differs for Huntington's disease patients with juvenile onset or adult onset. Ann Hum Genet. 2007 May; 71(Pt 3):295-301. PMID: 17181545
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Kraja AT, Borecki IB, North K, Tang W, Myers RH, Hopkins PN, Arnett D, Corbett J, Adelman A, Province MA. Longitudinal and age trends of metabolic syndrome and its risk factors: the Family Heart Study. Nutr Metab (Lond). 2006; 3:41. PMID: 17147796; PMCID: PMC1697811; DOI: 10.1186/1743-7075-3-41;
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Kishikawa S, Li JL, Gillis T, Hakky MM, Warby S, Hayden M, MacDonald ME, Myers RH, Gusella JF. Brain-derived neurotrophic factor does not influence age at neurologic onset of Huntington's disease. Neurobiol Dis. 2006 Nov; 24(2):280-5. PMID: 16962786
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Zeng W, Gillis T, Hakky M, Djoussé L, Myers RH, MacDonald ME, Gusella JF. Genetic analysis of the GRIK2 modifier effect in Huntington's disease. BMC Neurosci. 2006; 7:62. PMID: 16959037; PMCID: PMC1618398; DOI: 10.1186/1471-2202-7-62;
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Wilk JB, Myers RH, Pankow JS, Hunt SC, Leppert MF, Freedman BI, Province MA, Ellison RC. Adrenergic receptor polymorphisms associated with resting heart rate: the HyperGEN Study. Ann Hum Genet. 2006 Sep; 70(Pt 5):566-73.View Related Profiles. PMID: 16907703
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Li JL, Hayden MR, Warby SC, Durr A, Morrison PJ, Nance M, Ross CA, Margolis RL, Rosenblatt A, Squitieri F, Frati L, Gómez-Tortosa E, García CA, Suchowersky O, Klimek ML, Trent RJ, McCusker E, Novelletto A, Frontali M, Paulsen JS, Jones R, Ashizawa T, Lazzarini A, Wheeler VC, Prakash R, Xu G, Djoussé L, Mysore JS, Gillis T, Hakky M, Cupples LA, Saint-Hilaire MH, Cha JH, Hersch SM, Penney JB, Harrison MB, Perlman SL, Zanko A, Abramson RK, Lechich AJ, Duckett A, Marder K, Conneally PM, Gusella JF, MacDonald ME, Myers RH. Genome-wide significance for a modifier of age at neurological onset in Huntington's disease at 6q23-24: the HD MAPS study. BMC Med Genet. 2006; 7:71.View Related Profiles. PMID: 16914060; PMCID: PMC1586197; DOI: 10.1186/1471-2350-7-71;
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Avery CL, Freedman BI, Kraja AT, Borecki IB, Miller MB, Pankow JS, Arnett D, Lewis CE, Myers RH, Hunt SC, North KE. Genotype-by-sex interaction in the aetiology of type 2 diabetes mellitus: support for sex-specific quantitative trait loci in Hypertension Genetic Epidemiology Network participants. Diabetologia. 2006 Oct; 49(10):2329-36. PMID: 16906437
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Myers RH. Considerations for genomewide association studies in Parkinson disease. Am J Hum Genet. 2006 Jun; 78(6):1081-2. PMID: 16685659; PMCID: PMC1474090; DOI: 10.1086/504730;
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Sun M, Latourelle JC, Wooten GF, Lew MF, Klein C, Shill HA, Golbe LI, Mark MH, Racette BA, Perlmutter JS, Parsian A, Guttman M, Nicholson G, Xu G, Wilk JB, Saint-Hilaire MH, DeStefano AL, Prakash R, Williamson S, Suchowersky O, Labelle N, Growdon JH, Singer C, Watts RL, Goldwurm S, Pezzoli G, Baker KB, Pramstaller PP, Burn DJ, Chinnery PF, Sherman S, Vieregge P, Litvan I, Gillis T, MacDonald ME, Myers RH, Gusella JF. Influence of heterozygosity for parkin mutation on onset age in familial Parkinson disease: the GenePD study. Arch Neurol. 2006 Jun; 63(6):826-32.View Related Profiles. PMID: 16769863
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Lloret A, Dragileva E, Teed A, Espinola J, Fossale E, Gillis T, Lopez E, Myers RH, MacDonald ME, Wheeler VC. Genetic background modifies nuclear mutant huntingtin accumulation and HD CAG repeat instability in Huntington's disease knock-in mice. Hum Mol Genet. 2006 Jun 15; 15(12):2015-24. PMID: 16687439
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Feitosa MF, Province MA, Heiss G, Arnett DK, Myers RH, Pankow JS, Hopkins PN, Borecki IB. Evidence of QTL on 15q21 for high-density lipoprotein cholesterol: the National Heart, Lung, and Blood Institute Family Heart Study (NHLBI FHS). Atherosclerosis. 2007 Jan; 190(1):232-7. PMID: 16529751
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Laramie JM, Wilk JB, Hunt SC, Ellison RC, Chakravarti A, Boerwinkle E, Myers RH. Evidence for a gene influencing heart rate on chromosome 5p13-14 in a meta-analysis of genome-wide scans from the NHLBI Family Blood Pressure Program. BMC Med Genet. 2006; 7:17.View Related Profiles. PMID: 16509988; PMCID: PMC1413518; DOI: 10.1186/1471-2350-7-17;
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An P, Freedman BI, Rich SS, Mandel SA, Arnett DK, Myers RH, Chen YD, Hunt SC, Rao DC. Quantitative trait loci on chromosome 8q24 for pancreatic beta-cell function and 7q11 for insulin sensitivity in obese nondiabetic white and black families: evidence from genome-wide linkage scans in the NHLBI Hypertension Genetic Epidemiology Network (HyperGEN) study. Diabetes. 2006 Feb; 55(2):551-8. PMID: 16443794
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North KE, Avery CL, Lange LA, Borecki I, Myers RH. Evidence for association between a SNP at 12q24.3 and body fat and BMI under a chromosome 12 linkage peak: The HyperGEN study. 46th Annual Conference on Cardiovascular Disease Epidemiology. 2006; 113.
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Bielinski S, Pankow JS, Hopkins P, Eckfeldt JH, Hixon J, Liu YM, Register TC, Myers RH, Arnett DK. Genome-wide scans for loci affecting MCP-1 and ICAM-1 levels in the NHLBI family heart study follow-up examination. 46th Annual Conference on Cardiovascular Disease Epidemiology. 2006.
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Karamohamed S, Latourelle JC, Racette BA, Perlmutter JS, Wooten GF, Lew M, Klein C, Shill H, Golbe LI, Mark MH, Guttman M, Nicholson G, Wilk JB, Saint-Hilaire M, DeStefano AL, Prakash R, Tobin S, Williamson J, Suchowersky O, Labell N, Growdon BN, Singer C, Watts R, Goldwurm S, Pezzoli G, Baker KB, Giroux ML, Pramstaller PP, Burn DJ, Chinnery P, Sherman S, Vieregge P, Litvan I, Gusella JF, Myers RH, Parsian A. BDNF genetic variants are associated with onset age of familial Parkinson disease: GenePD Study. Neurology. 2005 Dec 13; 65(11):1823-5.View Related Profiles. PMID: 16344533
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Kraja AT, Hunt SC, Pankow JS, Myers RH, Heiss G, Lewis CE, Rao DC, Province MA. Quantitative trait loci for metabolic syndrome in the Hypertension Genetic Epidemiology Network study. Obes Res. 2005 Nov; 13(11):1885-90. PMID: 16339118
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Karamohamed S, Golbe LI, Mark MH, Lazzarini AM, Suchowersky O, Labelle N, Guttman M, Currie LJ, Wooten GF, Stacy M, Saint-Hilaire M, Feldman RG, Liu J, Shoemaker CM, Wilk JB, DeStefano AL, Latourelle JC, Xu G, Watts R, Growdon J, Lew M, Waters C, Vieregge P, Pramstaller PP, Klein C, Racette BA, Perlmutter JS, Parsian A, Singer C, Montgomery E, Baker K, Gusella JF, Herbert A, Myers RH. Absence of previously reported variants in the SCNA (G88C and G209A), NR4A2 (T291D and T245G) and the DJ-1 (T497C) genes in familial Parkinson's disease from the GenePD study. Mov Disord. 2005 Sep; 20(9):1188-91.View Related Profiles. PMID: 15966003
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Seong IS, Ivanova E, Lee JM, Choo YS, Fossale E, Anderson M, Gusella JF, Laramie JM, Myers RH, Lesort M, MacDonald ME. HD CAG repeat implicates a dominant property of huntingtin in mitochondrial energy metabolism. Hum Mol Genet. 2005 Oct 1; 14(19):2871-80. PMID: 16115812
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Yu K, Zhang S, Borecki I, Kraja A, Xiong C, Myers R, Province M. A haplotype similarity based transmission/disequilibrium test under founder heterogeneity. Ann Hum Genet. 2005 Jul; 69(Pt 4):455-67. PMID: 15996173
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Friedman JH, Trieschmann ME, Myers RH, Fernandez HH. Monozygotic twins discordant for Huntington disease after 7 years. Arch Neurol. 2005 Jun; 62(6):995-7. PMID: 15956172
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Lin JP, Myers RH, Almasy L, Coon HH, Arnett DK, Hong Y, Hunt SC. Linkage of the cholesterol 7alpha-hydroxylase gene and low-density lipoprotein cholesterol conditional on apolipoprotein E association: the National Heart, Lung, and Blood Institute Family Heart Study. Chin Med J (Engl). 2005 Mar 5; 118(5):362-9. PMID: 15780204
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Kraja AT, Hunt SC, Pankow JS, Myers RH, Heiss G, Lewis CE, Rao D, Province MA. An evaluation of the metabolic syndrome in the HyperGEN study. Nutr Metab (Lond). 2005 Jan 18; 2(1):2. PMID: 15656912; PMCID: PMC549210; DOI: 10.1186/1743-7075-2-2;
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North KE, Myers RH, Feitosa MF, Tang W, Lewis C, Hopkins P, Hixson J, Wagenknecht L, Kraja A, Borecki I. Genetic architecture of adiposity: Evidence for epistatic interactions on chromosomes 7 and 13 in the NHLBI Family Heart Study (FHS). 14th Annual Meeting of the International-Genetic-Epidemiology-Society. 2005.
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Feitosa MF, Province M, Heiss G, Arnett DK, Myers RH, Pankow JS, Hopkins P, Borecki I. A QTL on 15q21 influences HDL-cholesterol: NHLB-FHS. 14th Annual Meeting of the International-Genetic-Epidemiology-Society. 2005.
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Avery CL, Freedman BI, Heiss G, Kraja A, Rice T, Arnett D, Miller MB, Pankow JS, Lewis CE, Myers RH, Hunt SC, Almasy L, North KE. Linkage analysis of diabetes status among hypertensive families: the Hypertension Genetic Epidemiology Network study. Diabetes. 2004 Dec; 53(12):3307-12. PMID: 15561964
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Djoussé L, Pankow JS, Arnett DK, Eckfeldt JH, Myers RH, Ellison RC. Apolipoprotein E polymorphism modifies the alcohol-HDL association observed in the National Heart, Lung, and Blood Institute Family Heart Study. Am J Clin Nutr. 2004 Dec; 80(6):1639-44.View Related Profiles. PMID: 15585780
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Wilk JB, Djousse L, Arnett DK, Hunt SC, Province MA, Heiss G, Myers RH. Genome-wide linkage analyses for age at diagnosis of hypertension and early-onset hypertension in the HyperGEN study. Am J Hypertens. 2004 Sep; 17(9):839-44. PMID: 15363829
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Jiang Y, Wilk JB, Borecki I, Williamson S, DeStefano AL, Xu G, Liu J, Ellison RC, Province M, Myers RH. Common variants in the 5' region of the leptin gene are associated with body mass index in men from the National Heart, Lung, and Blood Institute Family Heart Study. Am J Hum Genet. 2004 Aug; 75(2):220-30.View Related Profiles. PMID: 15197684; PMCID: PMC1216056
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Myers RH. Huntington's disease genetics. NeuroRx. 2004 Apr; 1(2):255-62. PMID: 15717026; PMCID: PMC534940
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Djoussé L, Knowlton B, Hayden MR, Almqvist EW, Brinkman RR, Ross CA, Margolis RL, Rosenblatt A, Durr A, Dode C, Morrison PJ, Novelletto A, Frontali M, Trent RJ, McCusker E, Gómez-Tortosa E, Mayo Cabrero D, Jones R, Zanko A, Nance M, Abramson RK, Suchowersky O, Paulsen JS, Harrison MB, Yang Q, Cupples LA, Mysore J, Gusella JF, MacDonald ME, Myers RH. Evidence for a modifier of onset age in Huntington disease linked to the HD gene in 4p16. Neurogenetics. 2004 Jun; 5(2):109-14.View Related Profiles. PMID: 15029481; PMCID: PMC1866166
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Herrera VL, Didishvili T, Lopez LV, Myers RH, Ruiz-Opazo N. Genome-wide scan identifies novel QTLs for cholesterol and LDL levels in F2[Dahl RxS]-intercross rats. Circ Res. 2004 Mar 5; 94(4):446-52.View Related Profiles. PMID: 14739155
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Trieschmann MM, Friedman JH, Myers RH, Fernandez H. Monozygotic twins discordant for Huntington's disease after seven years. 8th International Congress of Parkinsons Disease and Movement Disoders. 2004.
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Djousse L, Pankow JS, Arnett DK, Eckfeldt JH, Myers RH, Ellison RC. Apolipoprotein E polymorphism modifies the alcohol-HDL association in the NHLBI Family Heart Study. 44th Annual Conference on Cardiovascular Disease Epidemiology. 2004; 109.
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Avery CL, Freedman BI, Heiss G, North KE, Myers RH et al. Linkage analysis of diabetes susceptibility among hypertensive families: The HyperGEN Study. Conference: 44th Annual Conference on Cardiovascular Disease Epidemiology. 2004; 109.
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Karamohamed S, DeStefano AL, Wilk JB, Shoemaker CM, Golbe LI, Mark MH, Lazzarini AM, Suchowersky O, Labelle N, Guttman M, Currie LJ, Wooten GF, Stacy M, Saint-Hilaire M, Feldman RG, Sullivan KM, Xu G, Watts R, Growdon J, Lew M, Waters C, Vieregge P, Pramstaller PP, Klein C, Racette BA, Perlmutter JS, Parsian A, Singer C, Montgomery E, Baker K, Gusella JF, Fink SJ, Myers RH, Herbert A. A haplotype at the PARK3 locus influences onset age for Parkinson's disease: the GenePD study. Neurology. 2003 Dec 9; 61(11):1557-61.View Related Profiles. PMID: 14663042
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Tang W, Miller MB, Rich SS, North KE, Pankow JS, Borecki IB, Myers RH, Hopkins PN, Leppert M, Arnett DK. Linkage analysis of a composite factor for the multiple metabolic syndrome: the National Heart, Lung, and Blood Institute Family Heart Study. Diabetes. 2003 Nov; 52(11):2840-7. PMID: 14578304
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Gagnon DR, Glickman ME, Myers RH, Cupples LA. The analysis of survival data with a non-susceptible fraction and dual censoring mechanisms. Stat Med. 2003 Oct 30; 22(20):3249-62.View Related Profiles. PMID: 14518026
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Wilk JB, DeStefano AL, Joost O, Myers RH, Cupples LA, Slater K, Atwood LD, Heard-Costa NL, Herbert A, O'Connor GT, Gottlieb DJ. Linkage and association with pulmonary function measures on chromosome 6q27 in the Framingham Heart Study. Hum Mol Genet. 2003 Nov 1; 12(21):2745-51.View Related Profiles. PMID: 12966033
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Li JL, Hayden MR, Almqvist EW, Brinkman RR, Durr A, Dodé C, Morrison PJ, Suchowersky O, Ross CA, Margolis RL, Rosenblatt A, Gómez-Tortosa E, Cabrero DM, Novelletto A, Frontali M, Nance M, Trent RJ, McCusker E, Jones R, Paulsen JS, Harrison M, Zanko A, Abramson RK, Russ AL, Knowlton B, Djoussé L, Mysore JS, Tariot S, Gusella MF, Wheeler VC, Atwood LD, Cupples LA, Saint-Hilaire M, Cha JH, Hersch SM, Koroshetz WJ, Gusella JF, MacDonald ME, Myers RH. A genome scan for modifiers of age at onset in Huntington disease: The HD MAPS study. Am J Hum Genet. 2003 Sep; 73(3):682-7.View Related Profiles. PMID: 12900792; PMCID: PMC1180695
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Djoussé L, Knowlton B, Hayden M, Almqvist EW, Brinkman R, Ross C, Margolis R, Rosenblatt A, Durr A, Dode C, Morrison PJ, Novelletto A, Frontali M, Trent RJ, McCusker E, Gómez-Tortosa E, Mayo D, Jones R, Zanko A, Nance M, Abramson R, Suchowersky O, Paulsen J, Harrison M, Yang Q, Cupples LA, Gusella JF, MacDonald ME, Myers RH. Interaction of normal and expanded CAG repeat sizes influences age at onset of Huntington disease. Am J Med Genet A. 2003 Jun 15; 119A(3):279-82.View Related Profiles. PMID: 12784292
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Wheelock VL, Tempkin T, Marder K, Nance M, Myers RH, Zhao H, Kayson E, Orme C, Shoulson I. Predictors of nursing home placement in Huntington disease. Neurology. 2003 Mar 25; 60(6):998-1001. PMID: 12654967
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Panhuysen CI, Cupples LA, Wilson PW, Herbert AG, Myers RH, Meigs JB. A genome scan for loci linked to quantitative insulin traits in persons without diabetes: the Framingham Offspring Study. Diabetologia. 2003 Apr; 46(4):579-87.View Related Profiles. PMID: 12739029
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Wilk JB, DeStefano AL, Arnett DK, Rich SS, Djousse L, Crapo RO, Leppert MF, Province MA, Cupples LA, Gottlieb DJ, Myers RH. A genome-wide scan of pulmonary function measures in the National Heart, Lung, and Blood Institute Family Heart Study. Am J Respir Crit Care Med. 2003 Jun 1; 167(11):1528-33.View Related Profiles. PMID: 12637344
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DeStefano AL, Gates GA, Heard-Costa N, Myers RH, Baldwin CT. Genomewide linkage analysis to presbycusis in the Framingham Heart Study. Arch Otolaryngol Head Neck Surg. 2003 Mar; 129(3):285-9.View Related Profiles. PMID: 12622536
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Wu X, Cooper RS, Boerwinkle E, Turner ST, Hunt S, Myers R, Olshen RA, Curb D, Zhu X, Kan D, Luke A. Combined analysis of genomewide scans for adult height: results from the NHLBI Family Blood Pressure Program. Eur J Hum Genet. 2003 Mar; 11(3):271-4. PMID: 12673281
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Gasser T, Bressman S, Dürr A, Higgins J, Klockgether T, Myers RH. State of the art review: molecular diagnosis of inherited movement disorders. Movement Disorders Society task force on molecular diagnosis. Mov Disord. 2003 Jan; 18(1):3-18. PMID: 12518296
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Mukhopadhyay N, Finegold DN, Larson MG, Cupples LA, Myers RH, Weeks DE. A genome-wide scan for loci affecting normal adult height in the Framingham Heart Study. Hum Hered. 2003; 55(4):191-201.View Related Profiles. PMID: 14566097
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Van Laer L, DeStefano AL, Myers RH, Flothmann K, Thys S, Fransen E, Gates GA, Van Camp G, Baldwin CT. Is DFNA5 a susceptibility gene for age-related hearing impairment? Eur J Hum Genet. 2002 Dec; 10(12):883-6.View Related Profiles. PMID: 12461698
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Djoussé L, Knowlton B, Cupples LA, Marder K, Shoulson I, Myers RH. Weight loss in early stage of Huntington's disease. Neurology. 2002 Nov 12; 59(9):1325-30.View Related Profiles. PMID: 12427878
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Karasik D, Myers RH, Hannan MT, Gagnon D, McLean RR, Cupples LA, Kiel DP. Mapping of quantitative ultrasound of the calcaneus bone to chromosome 1 by genome-wide linkage analysis. Osteoporos Int. 2002 Oct; 13(10):796-802.View Related Profiles. PMID: 12378368
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Karasik D, Myers RH, Cupples LA, Hannan MT, Gagnon DR, Herbert A, Kiel DP. Genome screen for quantitative trait loci contributing to normal variation in bone mineral density: the Framingham Study. J Bone Miner Res. 2002 Sep; 17(9):1718-27.View Related Profiles. PMID: 12211443
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Coon H, Eckfeldt JH, Leppert MF, Myers RH, Arnett DK, Heiss G, Province MA, Hunt SC. A genome-wide screen reveals evidence for a locus on chromosome 11 influencing variation in LDL cholesterol in the NHLBI Family Heart Study. Hum Genet. 2002 Sep; 111(3):263-9. PMID: 12215839
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Wilk JB, Myers RH, Zhang Y, Lewis CE, Atwood L, Hopkins PN, Ellison RC. Evidence for a gene influencing heart rate on chromosome 4 among hypertensives. Hum Genet. 2002 Aug; 111(2):207-13.View Related Profiles. PMID: 12189495
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Coady SA, Jaquish CE, Fabsitz RR, Larson MG, Cupples LA, Myers RH. Genetic variability of adult body mass index: a longitudinal assessment in framingham families. Obes Res. 2002 Jul; 10(7):675-81.View Related Profiles. PMID: 12105290
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Djoussé L, Myers RH, Province MA, Hunt SC, Eckfeldt JH, Evans G, Peacock JM, Ellison RC. Influence of apolipoprotein E, smoking, and alcohol intake on carotid atherosclerosis: National Heart, Lung, and Blood Institute Family Heart Study. Stroke. 2002 May; 33(5):1357-61.View Related Profiles. PMID: 11988615
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Maher NE, Currie LJ, Lazzarini AM, Wilk JB, Taylor CA, Saint-Hilaire MH, Feldman RG, Golbe LI, Wooten GF, Myers RH. Segregation analysis of Parkinson disease revealing evidence for a major causative gene. Am J Med Genet. 2002 May 1; 109(3):191-7.View Related Profiles. PMID: 11977177
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Demissie S, Cupples LA, Myers R, Aliabadi P, Levy D, Felson DT. Genome scan for quantity of hand osteoarthritis: the Framingham Study. Arthritis Rheum. 2002 Apr; 46(4):946-52.View Related Profiles. PMID: 11953971
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DeStefano AL, Lew MF, Golbe LI, Mark MH, Lazzarini AM, Guttman M, Montgomery E, Waters CH, Singer C, Watts RL, Currie LJ, Wooten GF, Maher NE, Wilk JB, Sullivan KM, Slater KM, Saint-Hilaire MH, Feldman RG, Suchowersky O, Lafontaine AL, Labelle N, Growdon JH, Vieregge P, Pramstaller PP, Klein C, Hubble JP, Reider CR, Stacy M, MacDonald ME, Gusella JF, Myers RH. PARK3 influences age at onset in Parkinson disease: a genome scan in the GenePD study. Am J Hum Genet. 2002 May; 70(5):1089-95.View Related Profiles. PMID: 11920285; PMCID: PMC447587
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Joost O, Wilk JB, Cupples LA, Harmon M, Shearman AM, Baldwin CT, O'Connor GT, Myers RH, Gottlieb DJ. Genetic loci influencing lung function: a genome-wide scan in the Framingham Study. Am J Respir Crit Care Med. 2002 Mar 15; 165(6):795-9.View Related Profiles. PMID: 11897646
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Meigs JB, Panhuysen CI, Myers RH, Wilson PW, Cupples LA. A genome-wide scan for loci linked to plasma levels of glucose and HbA(1c) in a community-based sample of Caucasian pedigrees: The Framingham Offspring Study. Diabetes. 2002 Mar; 51(3):833-40.View Related Profiles. PMID: 11872688
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Maher NE, Golbe LI, Lazzarini AM, Mark MH, Currie LJ, Wooten GF, Saint-Hilaire M, Wilk JB, Volcjak J, Maher JE, Feldman RG, Guttman M, Lew M, Waters CH, Schuman S, Suchowersky O, Lafontaine AL, Labelle N, Vieregge P, Pramstaller PP, Klein C, Hubble J, Reider C, Growdon J, Watts R, Montgomery E, Baker K, Singer C, Stacy M, Myers RH. Epidemiologic study of 203 sibling pairs with Parkinson's disease: the GenePD study. Neurology. 2002 Jan 8; 58(1):79-84.View Related Profiles. PMID: 11781409
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Karasik D, Hannan MT, Cupples LA, Myers RH, Kiel DP. Chromosomal mapping of quantitative trait loci for bone mineral density: The Framingham study. Osteoporosis International. 2002; 12:S11.
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Baldwin CT, Cupples LA, Joost O, Demissie S, Chaisson C, Mcalindon T, Myers RH, Felson D. Absence of linkage or association for osteoarthritis with the vitamin D receptor/type II collagen locus: the Framingham Osteoarthritis Study. J Rheumatol. 2002 Jan; 29(1):161-5.View Related Profiles. PMID: 11824954
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Karasik D, Hannan MT, Myers RH, Kiel DP. Stratified genome screen for quantitative trait loci contributing to normal bone mineral density (BMD) in the Framingham Study. American Journal of Human Biology. 2002; 14(1):117-118.
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Coon H, Leppert MF, Eckfeldt JH, Oberman A, Myers RH, Peacock JM, Province MA, Hopkins PN, Heiss G. Genome-wide linkage analysis of lipids in the Hypertension Genetic Epidemiology Network (HyperGEN) Blood Pressure Study. Arterioscler Thromb Vasc Biol. 2001 Dec; 21(12):1969-76. PMID: 11742872
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Feitosa MF, Borecki IB, Rich SS, Arnett DK, Sholinsky P, Myers RH, Leppert M, Province MA. Quantitative-trait loci influencing body-mass index reside on chromosomes 7 and 13: the National Heart, Lung, and Blood Institute Family Heart Study. Am J Hum Genet. 2002 Jan; 70(1):72-82. PMID: 11713718; PMCID: PMC384905
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Gottlieb DJ, Wilk JB, Harmon M, Evans JC, Joost O, Levy D, O'Connor GT, Myers RH. Heritability of longitudinal change in lung function. The Framingham study. Am J Respir Crit Care Med. 2001 Nov 1; 164(9):1655-9.View Related Profiles. PMID: 11719305
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Peacock JM, Arnett DK, Atwood LD, Myers RH, Coon H, Rich SS, Province MA, Heiss G. Genome scan for quantitative trait loci linked to high-density lipoprotein cholesterol: The NHLBI Family Heart Study. Arterioscler Thromb Vasc Biol. 2001 Nov; 21(11):1823-8. PMID: 11701472
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DeStefano AL, Golbe LI, Mark MH, Lazzarini AM, Maher NE, Saint-Hilaire M, Feldman RG, Guttman M, Watts RL, Suchowersky O, Lafontaine AL, Labelle N, Lew MF, Waters CH, Growdon JH, Singer C, Currie LJ, Wooten GF, Vieregge P, Pramstaller PP, Klein C, Hubble JP, Stacy M, Montgomery E, MacDonald ME, Gusella JF, Myers RH. Genome-wide scan for Parkinson's disease: the GenePD Study. Neurology. 2001 Sep 25; 57(6):1124-6.View Related Profiles. PMID: 11571351
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Glorioso N, Filigheddu F, Troffa C, Soro A, Parpaglia PP, Tsikoudakis A, Myers RH, Herrera VL, Ruiz-Opazo N. Interaction of alpha(1)-Na,K-ATPase and Na,K,2Cl-cotransporter genes in human essential hypertension. Hypertension. 2001 Aug; 38(2):204-9.View Related Profiles. PMID: 11509477
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O'Donnell CJ, Larson MG, Feng D, Sutherland PA, Lindpaintner K, Myers RH, D'Agostino RA, Levy D, Tofler GH. Genetic and environmental contributions to platelet aggregation: the Framingham heart study. Circulation. 2001 Jun 26; 103(25):3051-6.View Related Profiles. PMID: 11425767
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Hunt SC, Kronenberg F, Eckfeldt JH, Hopkins PN, Myers RH, Heiss G. Association of plasma bilirubin with coronary heart disease and segregation of bilirubin as a major gene trait: the NHLBI family heart study. Atherosclerosis. 2001 Feb 15; 154(3):747-54. PMID: 11257278
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Myers RH, Cupples LA, Taylor CA, Saint-Hilaire MH, Auerbach S, Feldman RG, Farrer LA. . The genetic component in Parkinson’s disease is half that of Alzheimer’s disease. Alzheimer’s Reports. 2001; 4:9-15.
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Gómez-Tortosa E, MacDonald ME, Friend JC, Taylor SA, Weiler LJ, Cupples LA, Srinidhi J, Gusella JF, Bird ED, Vonsattel JP, Myers RH. Quantitative neuropathological changes in presymptomatic Huntington's disease. Ann Neurol. 2001 Jan; 49(1):29-34. PMID: 11198293
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Wilk JB, Volcjak JS, Myers RH, Maher NE, Knowlton BA, Heard-Costa NL, Demissie S, Cupples LA, DeStefano AL. Family-based association tests for qualitative and quantitative traits using single-nucleotide polymorphism and microsatellite data. Genet Epidemiol. 2001; 21 Suppl 1:S364-9.View Related Profiles. PMID: 11793700
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Heard-Costa NL, Demissie S, DeStefano AL, Knowlton BA, Maher NE, Myers RH, Volcjak JS, Wilk JB, Cupples LA. Influence of marker heterozygosity and genetic heterogeneity on fine mapping. Genet Epidemiol. 2001; 21 Suppl 1:S467-72.View Related Profiles. PMID: 11793720
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Nance MA, Myers RH. Juvenile onset Huntington's disease--clinical and research perspectives. Ment Retard Dev Disabil Res Rev. 2001; 7(3):153-7. PMID: 11553930
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Zee RY, Myers RH, Hannan MT, Wilson PW, Ordovas JM, Schaefer EJ, Lindpaintner K, Kiel DP. Absence of linkage for bone mineral density to chromosome 12q12-14 in the region of the vitamin D receptor gene. Calcif Tissue Int. 2000 Dec; 67(6):434-9. PMID: 11289690
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Coon H, Myers RH, Borecki IB, Arnett DK, Hunt SC, Province MA, Djousse L, Leppert MF. Replication of linkage of familial combined hyperlipidemia to chromosome 1q with additional heterogeneous effect of apolipoprotein A-I/C-III/A-IV locus. The NHLBI Family Heart Study. Arterioscler Thromb Vasc Biol. 2000 Oct; 20(10):2275-80. PMID: 11031215
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Levy D, DeStefano AL, Larson MG, O'Donnell CJ, Lifton RP, Gavras H, Cupples LA, Myers RH. Evidence for a gene influencing blood pressure on chromosome 17. Genome scan linkage results for longitudinal blood pressure phenotypes in subjects from the framingham heart study. Hypertension. 2000 Oct; 36(4):477-83.View Related Profiles. PMID: 11040222
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Djoussé L, Myers RH, Coon H, Arnett DK, Province MA, Ellison RC. Smoking influences the association between apolipoprotein E and lipids: the National Heart, Lung, and Blood Institute Family Heart Study. Lipids. 2000 Aug; 35(8):827-31.View Related Profiles. PMID: 10984105
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Wilk JB, Djousse L, Arnett DK, Rich SS, Province MA, Hunt SC, Crapo RO, Higgins M, Myers RH. Evidence for major genes influencing pulmonary function in the NHLBI family heart study. Genet Epidemiol. 2000 Jul; 19(1):81-94. PMID: 10861898
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Salomaa V, Pankow J, Heiss G, Cakir B, Eckfeldt JH, Ellison RC, Myers RH, Hiller KM, Brantley KR, Morris TL, Weston BW. Genetic background of Lewis negative blood group phenotype and its association with atherosclerotic disease in the NHLBI family heart study. J Intern Med. 2000 Jun; 247(6):689-98.View Related Profiles. PMID: 10886491
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Shearman AM, Ordovas JM, Cupples LA, Schaefer EJ, Harmon MD, Shao Y, Keen JD, DeStefano AL, Joost O, Wilson PW, Housman DE, Myers RH. Evidence for a gene influencing the TG/HDL-C ratio on chromosome 7q32.3-qter: a genome-wide scan in the Framingham study. Hum Mol Genet. 2000 May 22; 9(9):1315-20.View Related Profiles. PMID: 10814713
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Hong Y, Leppert MF, Lin J, Hunt SC, Rich SS, Arnett DK, Myers RH, Eckfeldt J, Williams RR, Province MA. No evidence of linkage between the very-low-density lipoprotein receptor gene and fasting serum insulin or homeostasis model assessment insulin resistance index: the National Heart, Lung, and Blood Institute Family Heart Study. Metabolism. 2000 Mar; 49(3):293-7. PMID: 10726903
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Wilk JB, Djousse L, Borecki I, Atwood LD, Hunt SC, Rich SS, Eckfeldt JH, Arnett DK, Rao DC, Myers RH. Segregation analysis of serum uric acid in the NHLBI Family Heart Study. Hum Genet. 2000 Mar; 106(3):355-9.View Related Profiles. PMID: 10798367
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Kronenberg F, Rich SS, Sholinsky P, Arnett DK, Province ME, Myers RH, Eckfeldt JH, Williams RR, Hunt SC. Insulin and hypertension in the NHLBI Family Heart Study: a sibpair approach to a controversial issue. Am J Hypertens. 2000 Mar; 13(3):240-50. PMID: 10777027
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Marder K, Zhao H, Myers RH, Cudkowicz M, Kayson E, Kieburtz K, Orme C, Paulsen J, Penney JB, Siemers E, Shoulson I. Rate of functional decline in Huntington's disease. Huntington Study Group. Neurology. 2000 Jan 25; 54(2):452-8. PMID: 10668713
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Peacock JM, Atwood LD, Arnett DK, Borecki I, Hunt SC, Myers RH, Panklow JS, Hong YL, Rich S. Gene-environment interactions in the prediction of HDL cholesterol: Influence of waist-hip ratio. Circulation. 2000; 101(6):732.
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Wheelock V, Tempkin T, Marder K, Nance M, Myers RH, Zhao H. Do motor, behavioral or psychiatric correlates predict the need for institutional care in patients with Huntington's disease?. Annals of Neurology. 2000; 48(3):467.
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Province M, Hunt SC, Shannon W, Myers RH, Arnett DK, Pankow J, Lewis CE, Thirupathil Rao DC. Resolution of linkage heterogeneity in complex traits: regression tree linkage analysis of blood pressure in the NHLBI-HyperGEN study. The American Journal of Human Genetics. 2000; 67(4):52.
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Feitosa MF, Borecki I, Rich S, Arnett DK, Sholinsky P, Myers RH, Province M. Genome scan for body mass index in the National Heart, Lung, and Blood Institute Family Heart Study. The American Journal of Human Genetics. 2000; 67(4):49.
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Myers RH . Genetic modifiers and predictive testing in Huntington’s disease. NeuroScience News. Editor: Patrick McGeer. 2000; 3:23-29.
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Taylor CA, Saint-Hilaire MH, Cupples LA, Thomas CA, Burchard AE, Feldman RG, Myers RH. Environmental, medical, and family history risk factors for Parkinson's disease: a New England-based case control study. Am J Med Genet. 1999 Dec 15; 88(6):742-9.View Related Profiles. PMID: 10581500
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Zhang Y, Kreger BE, Dorgan JF, Cupples LA, Myers RH, Splansky GL, Schatzkin A, Ellison RC. Parental age at child's birth and son's risk of prostate cancer. The Framingham Study. Am J Epidemiol. 1999 Dec 1; 150(11):1208-12.View Related Profiles. PMID: 10588081
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Ellison RC, Myers RH, Zhang Y, Djoussé L, Knox S, Williams RR, Province MA. Effects of similarities in lifestyle habits on familial aggregation of high density lipoprotein and low density lipoprotein cholesterol: the NHLBI Family Heart Study. Am J Epidemiol. 1999 Nov 1; 150(9):910-8.View Related Profiles. PMID: 10547136
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MacDonald ME, Vonsattel JP, Shrinidhi J, Couropmitree NN, Cupples LA, Bird ED, Gusella JF, Myers RH. Evidence for the GluR6 gene associated with younger onset age of Huntington's disease. Neurology. 1999 Oct 12; 53(6):1330-2. PMID: 10522893
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Coon H, Leppert MF, Kronenberg F, Province MA, Myers RH, Arnett DK, Eckfeldt JH, Heiss G, Williams RR, Hunt SC. Evidence for a major gene accounting for mild elevation in LDL cholesterol: the NHLBI Family Heart Study. Ann Hum Genet. 1999 Sep; 63(Pt 5):401-12. PMID: 10735582
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Joost O, Taylor CA, Thomas CA, Cupples LA, Saint-Hilaire MH, Feldman RG, Baldwin CT, Myers RH. Absence of effect of seven functional mutations in the CYP2D6 gene in Parkinson's disease. Mov Disord. 1999 Jul; 14(4):590-5.View Related Profiles. PMID: 10435495
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Gates GA, Couropmitree NN, Myers RH. Genetic associations in age-related hearing thresholds. Arch Otolaryngol Head Neck Surg. 1999 Jun; 125(6):654-9. PMID: 10367922
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Feng D, Lindpaintner K, Larson MG, Rao VS, O'Donnell CJ, Lipinska I, Schmitz C, Sutherland PA, Silbershatz H, D'Agostino RB, Muller JE, Myers RH, Levy D, Tofler GH. Increased platelet aggregability associated with platelet GPIIIa PlA2 polymorphism: the Framingham Offspring Study. Arterioscler Thromb Vasc Biol. 1999 Apr; 19(4):1142-7.View Related Profiles. PMID: 10195947
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Ellison RC, Zhang Y, Myers RH, Swanson JL, Higgins M, Eckfeldt J. Lewis blood group phenotype as an independent risk factor for coronary heart disease (the NHLBI Family Heart Study). Am J Cardiol. 1999 Feb 1; 83(3):345-8.View Related Profiles. PMID: 10072221
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Wilk JB, Premkumar S, Nicolaou M, Myers RH, Maher NE, Harmon MD, Farrer LA, DeStefano AL, Cupples LA, Couropmitree NN. Stratification techniques to explore genotype environment interactions. Genet Epidemiol. 1999; 17 Suppl 1:S761-6.View Related Profiles. PMID: 10597527
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Karluk D, Myers RH, DiFiglia M, Vonsattel JP et al. Nonagenarians with Huntington disease (HD) have low CAG repeats. Journal of Neuropathology and Experimental Neurology. 1999; 58(5). View Publication
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Sieradzan KA, Mann DM. On the pathological progression of Huntington's disease. Ann Neurol. 1998 Jul; 44(1):148-9. PMID: 9667607
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Pocovi M, Cenarro A, Civeira F, Torralba MA, Perez-Calvo JI, Mozas P, Giraldo P, Giralt M, Myers RH, Cupples LA, Ordovas JM. Beta-glucocerebrosidase gene locus as a link for Gaucher's disease and familial hypo-alpha-lipoproteinaemia. Lancet. 1998 Jun 27; 351(9120):1919-23. PMID: 9654259
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Felson DT, Couropmitree NN, Chaisson CE, Hannan MT, Zhang Y, McAlindon TE, LaValley M, Levy D, Myers RH. Evidence for a Mendelian gene in a segregation analysis of generalized radiographic osteoarthritis: the Framingham Study. Arthritis Rheum. 1998 Jun; 41(6):1064-71.View Related Profiles. PMID: 9627016
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O'Donnell CJ, Lindpaintner K, Larson MG, Rao VS, Ordovas JM, Schaefer EJ, Myers RH, Levy D. Evidence for association and genetic linkage of the angiotensin-converting enzyme locus with hypertension and blood pressure in men but not women in the Framingham Heart Study. Circulation. 1998 May 12; 97(18):1766-72.View Related Profiles. PMID: 9603529
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ACMG/ASHG statement. Laboratory guidelines for Huntington disease genetic testing. The American College of Medical Genetics/American Society of Human Genetics Huntington Disease Genetic Testing Working Group. Am J Hum Genet. 1998 May; 62(5):1243-7. PMID: 9545416; PMCID: PMC1377103
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Jenkins BG, Rosas HD, Chen YC, Makabe T, Myers R, MacDonald M, Rosen BR, Beal MF, Koroshetz WJ. 1H NMR spectroscopy studies of Huntington's disease: correlations with CAG repeat numbers. Neurology. 1998 May; 50(5):1357-65. PMID: 9595987
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Givelber RJ, Couropmitree NN, Gottlieb DJ, Evans JC, Levy D, Myers RH, O'Connor GT. Segregation analysis of pulmonary function among families in the Framingham Study. Am J Respir Crit Care Med. 1998 May; 157(5 Pt 1):1445-51.View Related Profiles. PMID: 9603122
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Arnett DK, Borecki IB, Ludwig EH, Pankow JS, Myers R, Evans G, Folsom AR, Heiss G, Higgins M. Angiotensinogen and angiotensin converting enzyme genotypes and carotid atherosclerosis: the atherosclerosis risk in communities and the NHLBI family heart studies. Atherosclerosis. 1998 May; 138(1):111-6. PMID: 9678776
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Ewbank DC. Effects of age and ethnicity on the link between APOE epsilon4 and Alzheimer disease. JAMA. 1998 Feb 25; 279(8):580-1; author reply 581-2. PMID: 9486746
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Myers RH, Marans K, MacDonald ME . Huntington’s Disease. In: Genetic Instabilities and Hereditary Neurological Diseases. Editors: Stephen T. Warren and Robert T. Wells. Academic Press. 1998; 301-323.
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Feng DL, Lindpaintner K, Larson MG, O'Donnell C, Silbershatz H, Lipinska I, Sutherland PA, Muller JE, D'Agostino RB, Myers RH, Tofler GH . Factor VII gene polymorphism and cardiovascular disease: The Framingham Heart Study Circulation. 1998; 98: 2410-.
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O'Donnell CJ, Larson MG, Feng DL, Myers RH, Levy D, Tofler GH. Heritability of platelet aggregation in the Framingham Heart Study. Circulation. 1998; 97(8):830.
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Post WS, Larson MG, Myers RH, Galderisi M, Levy D. Heritability of left ventricular mass: the Framingham Heart Study. Hypertension. 1997 Nov; 30(5):1025-8.View Related Profiles. PMID: 9369250
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Farrer LA, Cupples LA, Haines JL, Hyman B, Kukull WA, Mayeux R, Myers RH, Pericak-Vance MA, Risch N, van Duijn CM. Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium. JAMA. 1997 Oct 22-29; 278(16):1349-56.View Related Profiles. PMID: 9343467
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Liao D, Myers R, Hunt S, Shahar E, Paton C, Burke G, Province M, Heiss G. Familial history of stroke and stroke risk. The Family Heart Study. Stroke. 1997 Oct; 28(10):1908-12. PMID: 9341694
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Kiel DP, Myers RH, Cupples LA, Kong XF, Zhu XH, Ordovas J, Schaefer EJ, Felson DT, Rush D, Wilson PW, Eisman JA, Holick MF. The BsmI vitamin D receptor restriction fragment length polymorphism (bb) influences the effect of calcium intake on bone mineral density. J Bone Miner Res. 1997 Jul; 12(7):1049-57.View Related Profiles. PMID: 9200004
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Taylor CA, Myers RH. Long-term impact of Huntington disease linkage testing. Am J Med Genet. 1997 Jun 27; 70(4):365-70. PMID: 9182776
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McNeil SM, Novelletto A, Srinidhi J, Barnes G, Kornbluth I, Altherr MR, Wasmuth JJ, Gusella JF, MacDonald ME, Myers RH. Reduced penetrance of the Huntington's disease mutation. Hum Mol Genet. 1997 May; 6(5):775-9. PMID: 9158152
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Penney JB, Vonsattel JP, MacDonald ME, Gusella JF, Myers RH. CAG repeat number governs the development rate of pathology in Huntington's disease. Ann Neurol. 1997 May; 41(5):689-92. PMID: 9153534
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DeStefano AL, Cupples LA, Myers RH, Farrer LA. Detecting linkage for a complex disease using simulated extended pedigrees. Genet Epidemiol. 1997; 14(6):981-6.View Related Profiles. PMID: 9433611
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Vasterling J, White RF, Marans K, Myers RH, Sax D. Neuropsychological functioning in juvenile/adolescent onset Huntington's disease: A case series. Archives of Clinical Neuropsychology. 1997; 12(4):421. View Publication
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Liao DP, Myers RH, Burke G, Province M, Shahar E, Paton C, Hunt S, Heiss G. Parental history of stroke and stroke risk - The FHS study. Stroke. 1997; 28(1):70.
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Vonsattel JPG, Zhao Y, Lenzi S, Hedley-Whyte ET, Myers RH et. al. ALZHEIMER DISEASE DOES NOT PROTECT THE NEOSTRIATUM IN COMBINED CASES OF HUNTINGTON (HD) AND ALZHEIMER DISEASE (AD). Journal of Neuropathology and Experimental Neurology. 1997; 56(5).
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Sax DS, Powsner R, Kim A, Tilak S, Bhatia R, Cupples LA, Myers RH. Evidence of cortical metabolic dysfunction in early Huntington's disease by single-photon-emission computed tomography. Mov Disord. 1996 Nov; 11(6):671-7.View Related Profiles. PMID: 8914093
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Pocovi M, Cenarro A, Civeira F, Myers RH, Casao E, Esteban M, Ordovas JM. Incomplete dominance of type III hyperlipoproteinemia is associated with the rare apolipoprotein E2 (Arg136-->Ser) variant in multigenerational pedigree studies. Atherosclerosis. 1996 Apr 26; 122(1):33-46. PMID: 8724110
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Lindpaintner K, Lee M, Larson MG, Rao VS, Pfeffer MA, Ordovas JM, Schaefer EJ, Wilson AF, Wilson PW, Vasan RS, Myers RH, Levy D. Absence of association or genetic linkage between the angiotensin-converting-enzyme gene and left ventricular mass. N Engl J Med. 1996 Apr 18; 334(16):1023-8.View Related Profiles. PMID: 8598840
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Myers RH, Schaefer EJ, Wilson PW, D'Agostino R, Ordovas JM, Espino A, Au R, White RF, Knoefel JE, Cobb JL, McNulty KA, Beiser A, Wolf PA. Apolipoprotein E epsilon4 association with dementia in a population-based study: The Framingham study. Neurology. 1996 Mar; 46(3):673-7.View Related Profiles. PMID: 8618665
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Podgor MJ, Hiller R. Associations of types of lens opacities between and within eyes of individuals: an application of second-order generalized estimating equations. The Framingham Eye Studies Group. Stat Med. 1996 Jan 30; 15(2):145-56. PMID: 8614751
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Gusella JF, McNeil S, Persichetti F, Srinidhi J, Novelletto A, Bird E, Faber P, Vonsattel JP, Myers RH, MacDonald ME. Huntington's disease. Cold Spring Harb Symp Quant Biol. 1996; 61:615-26. PMID: 9246488
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Statement on use of apolipoprotein E testing for Alzheimer disease. American College of Medical Genetics/American Society of Human Genetics Working Group on ApoE and Alzheimer disease. JAMA. 1995 Nov 22-29; 274(20):1627-9.View Related Profiles. PMID: 7474250
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Leeflang EP, Zhang L, Tavaré S, Hubert R, Srinidhi J, MacDonald ME, Myers RH, de Young M, Wexler NS, Gusella JF, et al. Single sperm analysis of the trinucleotide repeats in the Huntington's disease gene: quantification of the mutation frequency spectrum. Hum Mol Genet. 1995 Sep; 4(9):1519-26. PMID: 8541834
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Persichetti F, Ambrose CM, Ge P, McNeil SM, Srinidhi J, Anderson MA, Jenkins B, Barnes GT, Duyao MP, Kanaley L, et al. Normal and expanded Huntington's disease gene alleles produce distinguishable proteins due to translation across the CAG repeat. Mol Med. 1995 May; 1(4):374-83. PMID: 8521295; PMCID: PMC2230005
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Myers RH . Genetic testing for Huntington's disease. Scientific American; Science & Medicine. March/April. 1995; 4.
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Ramachandran VS, Levy D, Larson MG, Ordovas JM, Schaefer EJ, Myers RH, Lindpaintner K, Wilson PWF. 901-81 Association of a Molecular Variant of the Angiotensinogen Gene and Hypertension. Journal of the American College of Cardiology. 1995; 25(2). View Publication
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Levy D, Lindpaintner K, Larson MG, Ramachandran VS, Myers RH, Pfeffer MA, Ordovas JM, Schaefer EJ, Wilson PWF. 729-4 Left Ventricular Hypertrophy and the Deletion-Insertion Polymorphism of the Angiotensin Converting Enzyme Gene. Journal of the American College of Cardiology. 1995; 25(2). View Publication
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Myers RH, Schaefer EJ, Wilson PWF, D'Agostino R, Bachman DL, Ordovas JM, Au R, Cobb JL, Wolf PA . Apolipoprotein E allele 4 is associated with dementia in the Framingham study. In: Research Advances in Alzheimer’s Disease and Related Disorders. Editors: Iqbal K, Mortimer J, Winblad B, Wisniewski H. John Wiley & Sons, Ltd. Chichester England. 1995; 63-70.
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Ellison RC, Myers RH. Genetic and Familial Aspects of Disease. In: Introduction to Clinical Medicine. Mosby Yearbook. 1995; 9-12.
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Wilson PW, Myers RH, Larson MG, Ordovas JM, Wolf PA, Schaefer EJ. Apolipoprotein E alleles, dyslipidemia, and coronary heart disease. The Framingham Offspring Study. JAMA. 1994 Dec 7; 272(21):1666-71.View Related Profiles. PMID: 7966894
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Persichetti F, Srinidhi J, Kanaley L, Ge P, Myers RH, D'Arrigo K, Barnes GT, MacDonald ME, Vonsattel JP, Gusella JF, et al. Huntington's disease CAG trinucleotide repeats in pathologically confirmed post-mortem brains. Neurobiol Dis. 1994 Dec; 1(3):159-66. PMID: 9173995
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Familial aggregation of lens opacities: the Framingham Eye Study and the Framingham Offspring Eye Study. Am J Epidemiol. 1994 Sep 15; 140(6):555-64. PMID: 8067349
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Multani P, Myers RH, Blume HW, Schomer DL, Sotrel A. Neocortical dendritic pathology in human partial epilepsy: a quantitative Golgi study. Epilepsia. 1994 Jul-Aug; 35(4):728-36. PMID: 7521835
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Lazzarini AM, Myers RH, Zimmerman TR, Mark MH, Golbe LI, Sage JI, Johnson WG, Duvoisin RC. A clinical genetic study of Parkinson's disease: evidence for dominant transmission. Neurology. 1994 Mar; 44(3 Pt 1):499-506. PMID: 8145922
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Gaston S, Myers RH, White RF, Tanzi R, Feldman RG. Clinical phenotype of chromosome 14q24 associated FAD in the Italian-American (Feldman FAD Family) pedigree. Neurobiology of Aging. 1994; 15:S9. View Publication
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Myers RH, Friend JC, Cupples LA. Oligodendroglial proliferation in presymptomatic Huntington`s disease. 1994.
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MacDonald ME, Barnes G, Srinidhi J, Duyao MP, Ambrose CM, Myers RH, Gray J, Conneally PM, Young A, Penney J, et al. Gametic but not somatic instability of CAG repeat length in Huntington's disease. J Med Genet. 1993 Dec; 30(12):982-6. PMID: 8133508; PMCID: PMC1016628
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Myers RH, MacDonald ME, Gusella JF. Discrepancy resolved. Nat Genet. 1993 Nov; 5(3):215. PMID: 8110292
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Sotrel A, Williams RS, Kaufmann WE, Myers RH. Evidence for neuronal degeneration and dendritic plasticity in cortical pyramidal neurons of Huntington's disease: a quantitative Golgi study. Neurology. 1993 Oct; 43(10):2088-96. PMID: 8413971
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Myers RH, MacDonald ME, Koroshetz WJ, Duyao MP, Ambrose CM, Taylor SA, Barnes G, Srinidhi J, Lin CS, Whaley WL, et al. De novo expansion of a (CAG)n repeat in sporadic Huntington's disease. Nat Genet. 1993 Oct; 5(2):168-73. PMID: 8252042
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Kiely DK, Wolf PA, Cupples LA, Beiser AS, Myers RH. Familial aggregation of stroke. The Framingham Study. Stroke. 1993 Sep; 24(9):1366-71.View Related Profiles. PMID: 8362432
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Duyao M, Ambrose C, Myers R, Novelletto A, Persichetti F, Frontali M, Folstein S, Ross C, Franz M, Abbott M, et al. Trinucleotide repeat length instability and age of onset in Huntington's disease. Nat Genet. 1993 Aug; 4(4):387-92. PMID: 8401587
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Farrer LA, Cupples LA, Wiater P, Conneally PM, Gusella JF, Myers RH. The normal Huntington disease (HD) allele, or a closely linked gene, influences age at onset of HD. Am J Hum Genet. 1993 Jul; 53(1):125-30.View Related Profiles. PMID: 8317477; PMCID: PMC1682222
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A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. The Huntington's Disease Collaborative Research Group. Cell. 1993 Mar 26; 72(6):971-83. PMID: 8458085
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Koroshetz WJ, Myers RH, Martin JB. Neurology of Huntington's disease. In: The Molecular and Genetic Basis of Neurological Disease. Editors: Rosenberg RN, Prusiner SB, DiMauro S, Barchi RL, Kunkel LM. Butterworth & Heinemann. Boston,MA. 1993; 737-751.
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Sotrel A, Myers RH. CORTICAL PATHOLOGY IN HUNTINGTONS-DISEASE - MORPHOMETRIC AND OBSERVATIONAL STUDY. Journal of Neuropathology and Experimental Neurology. 1993; 52(3):280.
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Sotrel A, Myers RH. CORTICAL PATHOLOGY IN HUNTINGTON'S DISEASE. Journal of Neuropathology and Experimental Neurology. 1993; 52(3). View Publication
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Cupples LA, Myers RH. Segregation analysis for high density lipoprotein in the Berkeley data. Genet Epidemiol. 1993; 10(6):629-34.View Related Profiles. PMID: 8314072
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Diamond R, White RF, Myers RH, Mastromauro C, Koroshetz WJ, Butters N, Rothstein DM, Moss MB, Vasterling J. Evidence of presymptomatic cognitive decline in Huntington's disease. J Clin Exp Neuropsychol. 1992 Nov; 14(6):961-75.View Related Profiles. PMID: 1452640
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Ogawa T, Matson WR, Beal MF, Myers RH, Bird ED, Milbury P, Saso S. Kynurenine pathway abnormalities in Parkinson's disease. Neurology. 1992 Sep; 42(9):1702-6. PMID: 1513457
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Genest JJ, Martin-Munley SS, McNamara JR, Ordovas JM, Jenner J, Myers RH, Silberman SR, Wilson PW, Salem DN, Schaefer EJ. Familial lipoprotein disorders in patients with premature coronary artery disease. Circulation. 1992 Jun; 85(6):2025-33. PMID: 1534286
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MacDonald ME, Novelletto A, Lin C, Tagle D, Barnes G, Bates G, Taylor S, Allitto B, Altherr M, Myers R, et al. The Huntington's disease candidate region exhibits many different haplotypes. Nat Genet. 1992 May; 1(2):99-103. PMID: 1302016
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Farrer LA, Cupples LA, Kiely DK, Conneally PM, Myers RH. Inverse relationship between age at onset of Huntington disease and paternal age suggests involvement of genetic imprinting. Am J Hum Genet. 1992 Mar; 50(3):528-35.View Related Profiles. PMID: 1531729; PMCID: PMC1684271
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Brand FN, Kiely DK, Kannel WB, Myers RH. Family patterns of coronary heart disease mortality: the Framingham Longevity Study. J Clin Epidemiol. 1992 Feb; 45(2):169-74. PMID: 1573433
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Adrienne Cupples L, Risch N, Farrer L, Myers RH. Reply to Krawczak and Bockel. The American Journal of Human Genetics. 1992; 50(3).
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Farrer L, Adrienne Cupples L, Myers RH, Connor L, Growdon JH. Reply to Tzourio et al. The American Journal of Human Genetics. 1992; 50(3).
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Vonsattel JP, Myers RH, Bird ED, Ge P, Richardson EP. [Huntington disease: 7 cases with relatively preserved neostriatal islets]. Rev Neurol (Paris). 1992; 148(2):107-16. PMID: 1534925
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Farrer LA, Myers RH, Cupples LA. Segregation analysis of total nevus density and estimation of lifetime risk and average onset age of melanoma. Cytogenet Cell Genet. 1992; 59(2-3):197-9.View Related Profiles. PMID: 1737499
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White RF, Vasterling J, Koroshetz W, Myers RH . Neuropsychology of Huntington's disease. In: Clinical Syndromes in Adult Neuropsychology: The Practitioner's Handbook. Editor: White RF. Elsevier. Amsterdam. 1992; 213-251.
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Koroshetz WJ, Myers RH, Martin JB. The Neurology of Huntington's disease. In: Movement Disorders in Neurology and Neuropsychiatry. Editors: Joseph AR and Young RR. Blackwell Scientific Publications. Cambridge,MA. 1992; 167-177.
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Vonsattel JP, Myers RH, Hedley-Whyte ET, Ropper AH, Bird ED, Richardson EP. Cerebral amyloid angiopathy without and with cerebral hemorrhages: a comparative histological study. Ann Neurol. 1991 Nov; 30(5):637-49. PMID: 1763890
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Myers RH, Vonsattel JP, Paskevich PA, Kiely DK, Stevens TJ, Cupples LA, Richardson EP, Bird ED. Decreased neuronal and increased oligodendroglial densities in Huntington's disease caudate nucleus. J Neuropathol Exp Neurol. 1991 Nov; 50(6):729-42.View Related Profiles. PMID: 1836225
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Myers RH, Sax DS, Koroshetz WJ, Mastromauro C, Cupples LA, Kiely DK, Pettengill FK, Bird ED. Factors associated with slow progression in Huntington's disease. Arch Neurol. 1991 Aug; 48(8):800-4.View Related Profiles. PMID: 1832854
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Cupples LA, Risch N, Farrer LA, Myers RH. Estimation of morbid risk and age at onset with missing information. Am J Hum Genet. 1991 Jul; 49(1):76-87.View Related Profiles. PMID: 1829582; PMCID: PMC1683228
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Sotrel A, Paskevich PA, Kiely DK, Bird ED, Williams RS, Myers RH. Morphometric analysis of the prefrontal cortex in Huntington's disease. Neurology. 1991 Jul; 41(7):1117-23. PMID: 1829794
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Meissen GJ, Mastromauro CA, Kiely DK, McNamara DS, Myers RH. Understanding the decision to take the predictive test for Huntington disease. Am J Med Genet. 1991 Jun 15; 39(4):404-10. PMID: 1678928
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Farrer LA, Myers RH, Connor L, Cupples LA, Growdon JH. Segregation analysis reveals evidence of a major gene for Alzheimer disease. Am J Hum Genet. 1991 Jun; 48(6):1026-33.View Related Profiles. PMID: 2035523; PMCID: PMC1683119
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Doolittle TH, Myers RH, Lehrich JR, Birnbaum G, Sheremata W, Franklin GM, Nelson LM, Hauser SL. Multiple sclerosis sibling pairs: clustered onset and familial predisposition. Neurology. 1990 Oct; 40(10):1546-52. PMID: 2215946
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Myers RH, Kiely DK, Cupples LA, Kannel WB. Parental history is an independent risk factor for coronary artery disease: the Framingham Study. Am Heart J. 1990 Oct; 120(4):963-9.View Related Profiles. PMID: 2220549
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St George-Hyslop PH, Haines JL, Farrer LA, Polinsky R, Van Broeckhoven C, Goate A, McLachlan DR, Orr H, Bruni AC, Sorbi S, Rainero I, Foncin JF, Pollen D, Cantu JM, Tupler R, Voskresenskaya N, Mayeux R, Growden J, Fried VA, Myers RH, Nee L, Backhovens H, Martin JJ, Rossor M, Owen MJ, Mullan M, Percy ME, Karlinsky H, Rich S, Heston L, Montesi M, Mortilla M, Nacmias N, Gusella JF, Hardy JA, et al. Genetic linkage studies suggest that Alzheimer's disease is not a single homogeneous disorder. Nature. 1990 Sep 13; 347(6289):194-7.View Related Profiles. PMID: 2395471
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Farrer LA, Myers RH, Cupples LA, St George-Hyslop PH, Bird TD, Rossor MN, Mullan MJ, Polinsky R, Nee L, Heston L, et al. Transmission and age-at-onset patterns in familial Alzheimer's disease: evidence for heterogeneity. Neurology. 1990 Mar; 40(3 Pt 1):395-403.View Related Profiles. PMID: 2314579
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Breitner JCS, Farrer L, Myers RH, Adrienne Cupples L, Growdon JH. Estimation of familial risk in Alzheimer's disease. Annals of Neurology. 1990; 27(3). View Publication
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St George-Hyslop PH, Haines JL, Polinsky RJ, Tanzi RE, Farrer L, Myers RH, Gusella JF. Molecular genetics of familial Alzheimer's disease. Can J Neurol Sci. 1989 Nov; 16(4 Suppl):465-7.View Related Profiles. PMID: 2680005
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Sax DS, Bird ED, Gusella JF, Myers RH. Phenotypic variation in 2 Huntington's disease families with linkage to chromosome 4. Neurology. 1989 Oct; 39(10):1332-6. PMID: 2529452
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Myers RH, Leavitt J, Farrer LA, Jagadeesh J, McFarlane H, Mastromauro CA, Mark RJ, Gusella JF. Homozygote for Huntington disease. Am J Hum Genet. 1989 Oct; 45(4):615-8.View Related Profiles. PMID: 2535231; PMCID: PMC1683503
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Schildkraut JM, Myers RH, Cupples LA, Kiely DK, Kannel WB. Coronary risk associated with age and sex of parental heart disease in the Framingham Study. Am J Cardiol. 1989 Sep 15; 64(10):555-9. PMID: 2782245
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MacDonald ME, Cheng SV, Zimmer M, Haines JL, Poustka A, Allitto B, Smith B, Whaley WL, Romano DM, Jagadeesh J, et al. Clustering of multiallele DNA markers near the Huntington's disease gene. J Clin Invest. 1989 Sep; 84(3):1013-6. PMID: 2569477; PMCID: PMC329749
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St George-Hyslop PH, Myers RH, Haines JL, Farrer LA, Tanzi RE, Abe K, James MF, Conneally PM, Polinsky RJ, Gusella JF. Familial Alzheimer's disease: progress and problems. Neurobiol Aging. 1989 Sep-Oct; 10(5):417-25.View Related Profiles. PMID: 2682321
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Conneally PM, Haines JL, Tanzi RE, Wexler NS, Penchaszadeh GK, Harper PS, Folstein SE, Cassiman JJ, Myers RH, Young AB, et al. Huntington disease: no evidence for locus heterogeneity. Genomics. 1989 Aug; 5(2):304-8. PMID: 2571579
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Mastromauro CA, Meissen GJ, Cupples LA, Kiely DK, Berkman B, Myers RH. Estimation of fertility and fitness in Huntington disease in New England. Am J Med Genet. 1989 Jun; 33(2):248-54.View Related Profiles. PMID: 2527461
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Farrer LA, O'Sullivan DM, Cupples LA, Growdon JH, Myers RH. Assessment of genetic risk for Alzheimer's disease among first-degree relatives. Ann Neurol. 1989 May; 25(5):485-93.View Related Profiles. PMID: 2774490
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St George-Hyslop PH, Myers RH, Haines JI, Farrer L, Tanzi R, Conneally PM, Polinsky RJ, Gusella JF. Authors' response to commentaries. Neurobiology of Aging. 1989; 10(5):446-448. View Publication
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Cupples LA, Terrin NC, Myers RH, D'Agostino RB. Using survival methods to estimate age-at-onset distributions for genetic diseases with an application to Huntington disease. Genet Epidemiol. 1989; 6(2):361-71.View Related Profiles. PMID: 2524419
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Haines JL, Farrer LA, Myers RH. Linkage map of anonymous loci near the CF gene. Prog Clin Biol Res. 1989; 329:29-34.View Related Profiles. PMID: 2622958
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St George-Hyslop PH, Tanzi RE, Haines JL, Polinsky RJ, Farrer L, Myers RH, Gusella JF. Molecular genetics of familial Alzheimer's disease. Eur Neurol. 1989; 29 Suppl 3:25-7.View Related Profiles. PMID: 2693103
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Farrer LA, Myers RH, Cupples LA, Conneally PM. Considerations in using linkage analysis as a presymptomatic test for Huntington's disease. J Med Genet. 1988 Sep; 25(9):577-88.View Related Profiles. PMID: 2903248; PMCID: PMC1051534
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Meissen GJ, Myers RH, Mastromauro CA, Koroshetz WJ, Klinger KW, Farrer LA, Watkins PA, Gusella JF, Bird ED, Martin JB. Predictive testing for Huntington's disease with use of a linked DNA marker. N Engl J Med. 1988 Mar 3; 318(9):535-42.View Related Profiles. PMID: 2893260
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Myers RH, Vonsattel JP, Stevens TJ, Cupples LA, Richardson EP, Martin JB, Bird ED. Clinical and neuropathologic assessment of severity in Huntington's disease. Neurology. 1988 Mar; 38(3):341-7. PMID: 2964565
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Farrer L, Haines J, Gusella J, Myers RH et al. Genetics and Alzheimer’s Disease. Molecular Genetic Strategies in Familial Alzheimer’s Disease: Theoretical and Practical Considerations. 1988; 109-115. View Publication
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Gilliam TC, Bucan M, MacDonald ME, Zimmer M, Haines JL, Cheng SV, Pohl TM, Meyers RH, Whaley WL, Allitto BA, et al. A DNA segment encoding two genes very tightly linked to Huntington's disease. Science. 1987 Nov 13; 238(4829):950-2. PMID: 2890209
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St George-Hyslop PH, Tanzi RE, Polinsky RJ, Neve RL, Pollen D, Drachman D, Growdon J, Cupples LA, Nee L, Myers RH, et al. Absence of duplication of chromosome 21 genes in familial and sporadic Alzheimer's disease. Science. 1987 Oct 30; 238(4827):664-6. PMID: 2890206
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St George-Hyslop PH, Tanzi RE, Polinsky RJ, Haines JL, Nee L, Watkins PC, Myers RH, Feldman RG, Pollen D, Drachman D, et al. The genetic defect causing familial Alzheimer's disease maps on chromosome 21. Science. 1987 Feb 20; 235(4791):885-90. PMID: 2880399
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Mastromauro C, Myers RH, Berkman B. Attitudes toward presymptomatic testing in Huntington disease. Am J Med Genet. 1987 Feb; 26(2):271-82. PMID: 2949611
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St George-Hyslop P, Polinsky R, Haines J, Nee L, Tanzi R, Conneally P, Growdon J, Myers R, Pollen D, Drachman D, et al. Search for the familial Alzheimer's disease gene. J Neural Transm Suppl. 1987; 24:13-21. PMID: 2890708
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Vonsattel JP, Myers RH, Stevens TJ, Ferrante RJ, Paskevich PA, Bird ED, Richardson EP. Huntington's disease: Neuropathological grading. In: The Basal Ganglia: Structure and Function. Editors: Carpenter MB, Jayaraman A. Plenum Press. New York,NY. 1987; 515-531.
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Gusella JF, St. George-Hyslop PH, Tanzi RE, Polinsky RJ, Haines JL, Nee L, Watkins PC, Steward GD, Neve R, Bruns GA, Myers RH, Feldman RG, Pollen D, Drachman D, Bruni A, Foncin JF, Frommelt P, Amaducci L, Conneally PM. . Genetic Linkage analysis of familial Alzheimer's disease. In: Molecular Neuropathology of Aging. Davies P, Finch CE (Editors). Banbury Report 27, Cold Spring Harbor Laboratory. 1987; 425-442.
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Myers RH. Genetic linkage test for Huntington's disease. The Genetic Resource. 1987; 4:15-18.
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Vonsattel JP, Myers RH, Stevens TJ, Bird ED et al. The Basal Ganglia II: Structure and Function—Current Concepts. Huntington’s Disease: Neuropathological Grading. 1987; 515-531. View Publication
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Mastromauro C, Myers RH, Berkman B. Change in attitudes toward presymptomatic testing in Huntington disease. Am J Med Genet. 1986 Jun; 24(2):369-71. PMID: 3013007
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Falek A, Myers RH, Craddick R. Prediction in the onset and detection of Huntington's disease. In: Life Span Research on the Prediction of Psychopathology. Editors: Erlenmayer-Kimling L, Miller N, Dohrenwend BS. Erlbaum Publishers. New York,NY. 1986; 275-285.
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Vonsattel JP, Myers RH, Stevens TJ, Ferrante RJ, Bird ED, Richardson EP. Neuropathological classification of Huntington's disease. J Neuropathol Exp Neurol. 1985 Nov; 44(6):559-77. PMID: 2932539
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Myers RH, Sax DS, Schoenfeld M, Bird ED, Wolf PA, Vonsattel JP, White RF, Martin JB. Late onset of Huntington's disease. J Neurol Neurosurg Psychiatry. 1985 Jun; 48(6):530-4.View Related Profiles. PMID: 3159849; PMCID: PMC1028368
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Myers RH, Cupples LA, Schoenfeld M, D'Agostino RB, Terrin NC, Goldmakher N, Wolf PA. Maternal factors in onset of Huntington disease. Am J Hum Genet. 1985 May; 37(3):511-23.View Related Profiles. PMID: 3159258; PMCID: PMC1684593
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Myers RH, Schoenfeld M, Bird ED. Huntington's disease: genetics, chemical pathology, and management. Prog Med Genet. 1985; 6:91-122. PMID: 2873625
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Shafer DA, Myers RH, Saltzman D. Siabon (Siamang-Gibbon) Hybrids. In: The Lesser Apes: Evolutionary and Behavioral Biology. Editors: Preushoft H, Chivers D, Brockelman W, Creel N. Edinburgh University Press. Edinburgh. 1985.
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Schoenfeld M, Myers RH, Cupples LA, Berkman B, Sax DS, Clark E. Increased rate of suicide among patients with Huntington's disease. J Neurol Neurosurg Psychiatry. 1984 Dec; 47(12):1283-7. PMID: 6239910; PMCID: PMC1028135
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Schoenfeld M, Myers RH, Berkman B, Clark E. Potential impact of a predictive test on the gene frequency of Huntington disease. Am J Med Genet. 1984 Jul; 18(3):423-9. PMID: 6236692
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Savage D, Padgett S, Myers R, Anderson S, Levy D, Plehn J, Finizola B, Castelli W. Noninvasive cardiology tools and endpoints in genetic epidemiology: the Framingham Study. Prog Clin Biol Res. 1984; 147:407-17. PMID: 6539918
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Schoenfeld M, Berkman B, Myers RH, Clark E. Attitudes toward marriage and childbearing of individuals at risk for Huntington's disease. Soc Work Health Care. 1984; 9(4):73-81. PMID: 6237443
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Sudarsky L, Myers RH, Walshe TM. Huntington's disease in monozygotic twins reared apart. J Med Genet. 1983 Dec; 20(6):408-11. PMID: 6228662; PMCID: PMC1049168
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Myers RH, Goldman D, Bird ED, Sax DS, Merril CR, Schoenfeld M, Wolf PA. Maternal transmission in Huntington's disease. Lancet. 1983 Jan 29; 1(8318):208-10.View Related Profiles. PMID: 6130245
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Myers RH, Growdon JH, Bird ED, Feldman RG, Martin JB. False-negative results with levodopa for early detection of Huntington's disease. N Engl J Med. 1982 Aug 26; 307(9):561-2. PMID: 6212764
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Myers RH, Madden JJ, Teague JL, Falek A. Factors related to onset age of Huntington disease. Am J Hum Genet. 1982 May; 34(3):481-8. PMID: 6211092; PMCID: PMC1685335
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Myers RH, Martin JB. Huntington's Disease. Seminars in Neurology. 1982; 2:365-372.
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Sinex FM, Myers RH. Alzheimer's disease, Down's syndrome, and aging: the genetic approach. Ann N Y Acad Sci. 1982; 396:3-13. PMID: 6217775
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Wolkin JR, Myers RH . Characteristics of a Gibbon-Siamang hybrid ape. International Journal of Primatology. 1980; 1:203-221.
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Myers RH, Falek A. Quantification of muscle tremor of Huntington's disease patients and their offspring in an early detection study. Biol Psychiatry. 1979 Oct; 14(5):777-89. PMID: 159079
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Myers RH, Shafer DA. Hybrid ape offspring of a mating of gibbon and siamang. Science. 1979 Jul 20; 205(4403):308-10. PMID: 451603
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Myers RH. The chromosome connection: the theory of evolution is evolving. The Sciences. 1979; 20(5):18-20.
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Myers RH, De Castro JM. Learned aversions to intracerebral carbachol. Physiol Behav. 1977 Oct; 19(4):467-72. PMID: 613337
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Myers RH, Hobbs ME, Gross PM. Regularities in the Densities of Dilute Solutions of Some Monochlorobenzotrihalides1. Journal of the American Chemical Society. 1954; 76(18). View Publication