Adam Labadorf, PhD
Assistant Professor
Boston University School of Medicine
Dept of Medicine
Neurology

PhD, Boston University
MS, Colorado State University

Pronouns: he/him/his



Adam received his PhD in Bioinformatics from Boston University. His primary research interest is to better understand the genomics characteristics of neurodegeneration in human tissue using bioinformatics and machine learning approaches. His neurodegenerative disease research involves identifying commonalities and differences between different neurodegenerative diseases, with the goal of finding common pathological mechanisms that may lead to novel treatment modalities. He has particular expertise in the analysis of post mortem human brain tissue and cerebrospinal fluid transcriptomes, and has made significant contributions to our understanding of Huntington's, Parkinson's, and Chronic Traumatic Encephalopathy (CTE). He also has methodological interests in metatranscriptomics in contexts ranging from Caribbean coral ecologies to connections between the central nervous system and the human microbiome. In addition to his independent research, he serves as Director of Graduate Studies for the BU Bioinformatics Masters program, as Director of Bioinformatics for the VA PTSD Brain Bank, and is a member of the BU Alzheimer's Disease Research Center and BU CTE Center.


Bioinformatics Services for the VA Brain Bank
09/21/2020 - 09/20/2021 (PI)
Department of Veterans Administration




Title


Yr Title Project-Sub Proj Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. Floro J, Dai A, Metzger A, Mora-Martin A, Ganem NJ, Cifuentes D, Wu CS, Dalal J, Lyons SM, Labadorf A, Flynn RL. SDE2 is an essential gene required for ribosome biogenesis and the regulation of alternative splicing. Nucleic Acids Res. 2021 Sep 20; 49(16):9424-9443.View Related Profiles. PMID: 34365507; PMCID: PMC8450105; DOI: 10.1093/nar/gkab647;
     
  2. Logue MW, Zhou Z, Morrison FG, Wolf EJ, Daskalakis NP, Chatzinakos C, Georgiadis F, Labadorf AT, Girgenti MJ, Young KA, Williamson DE, Zhao X, Grenier JG, Huber BR, Miller MW. Gene expression in the dorsolateral and ventromedial prefrontal cortices implicates immune-related gene networks in PTSD. Neurobiol Stress. 2021 Nov; 15:100398.View Related Profiles. PMID: 34646915; PMCID: PMC8498459; DOI: 10.1016/j.ynstr.2021.100398;
     
  3. Cherry JD, Agus F, Dixon E, Huber B, Alvarez VE, Mez J, McKee AC, Labadorf A, Stein TD. Differential gene expression in the cortical sulcus compared to the gyral crest within the early stages of chronic traumatic encephalopathy. Free Neuropathol. 2021; 2.View Related Profiles. PMID: 34485990; PMCID: PMC8415801; DOI: 10.17879/freeneuropathology-2021-3453;
     
  4. Carrasco Pro S, Bulekova K, Gregor B, Labadorf A, Fuxman Bass JI. Publisher Correction: Prediction of genome-wide effects of single nucleotide variants on transcription factor binding. Sci Rep. 2021 Feb 03; 11(1):3395.View Related Profiles. PMID: 33536541; PMCID: PMC7859389; DOI: 10.1038/s41598-021-83094-3;
     
  5. Carrasco Pro S, Bulekova K, Gregor B, Labadorf A, Fuxman Bass JI. Prediction of genome-wide effects of single nucleotide variants on transcription factor binding. Sci Rep. 2020 10 19; 10(1):17632.View Related Profiles. PMID: 33077858; PMCID: PMC7572467; DOI: 10.1038/s41598-020-74793-4;
     
  6. Raghunathan R, Hogan JD, Labadorf A, Myers RH, Zaia J. A glycomics and proteomics study of aging and Parkinson's disease in human brain. Sci Rep. 2020 07 30; 10(1):12804.View Related Profiles. PMID: 32733076; PMCID: PMC7393382; DOI: 10.1038/s41598-020-69480-3;
     
  7. Guillon A, Arafa EI, Barker KA, Belkina AC, Martin I, Shenoy AT, Wooten AK, Lyon De Ana C, Dai A, Labadorf A, Hernandez Escalante J, Dooms H, Blasco H, Traber KE, Jones MR, Quinton LJ, Mizgerd JP. Pneumonia recovery reprograms the alveolar macrophage pool. JCI Insight. 2020 02 27; 5(4).View Related Profiles. PMID: 31990682; PMCID: PMC7101156; DOI: 10.1172/jci.insight.133042;
     
  8. Agus F, Crespo D, Myers RH, Labadorf A. The caudate nucleus undergoes dramatic and unique transcriptional changes in human prodromal Huntington's disease brain. BMC Med Genomics. 2019 10 16; 12(1):137.View Related Profiles. PMID: 31619230; PMCID: PMC6796419; DOI: 10.1186/s12920-019-0581-9;
     
  9. Panier S, Maric M, Hewitt G, Mason-Osann E, Gali H, Dai A, Labadorf A, Guervilly JH, Ruis P, Segura-Bayona S, Belan O, Marzec P, Gaillard PHL, Flynn RL, Boulton SJ. SLX4IP Antagonizes Promiscuous BLM Activity during ALT Maintenance. Mol Cell. 2019 10 03; 76(1):27-43.e11.View Related Profiles. PMID: 31447390; PMCID: PMC6863466; DOI: 10.1016/j.molcel.2019.07.010;
     
  10. Cardamone MD, Orofino J, Labadorf A, Perissi V. Chromatin Immunoprecipitation of Murine Brown Adipose Tissue. J Vis Exp. 2018 11 21; (141).View Related Profiles. PMID: 30531713; PMCID: PMC6684207; DOI: 10.3791/58682;
     
Showing 10 of 31 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 31 publications over 11 distinct years, with a maximum of 5 publications in 2016

YearPublications
20101
20112
20121
20134
20154
20165
20172
20183
20192
20203
20214
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75 E. Concord Street
Boston MA 02118
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