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Cupples LA, Arruda HT, Benjamin EJ, D'Agostino RB, Demissie S, DeStefano AL, Dupuis J, Falls KM, Fox CS, Gottlieb DJ, Govindaraju DR, Guo CY, Heard-Costa NL, Hwang SJ, Kathiresan S, Kiel DP, Laramie JM, Larson MG, Levy D, Liu CY, Lunetta KL, Mailman MD, Manning AK, Meigs JB, Murabito JM, Newton-Cheh C, O'Connor GT, O'Donnell CJ, Pandey M, Seshadri S, Vasan RS, Wang ZY, Wilk JB, Wolf PA, Yang Q, Atwood LD. The Framingham Heart Study 100K SNP genome-wide association study resource: overview of 17 phenotype working group reports. BMC Med Genet. 2007; 8 Suppl 1:S1.View Related Profiles. PMID: 17903291; PMCID: PMC1995613; DOI: 10.1186/1471-2350-8-S1-S1;
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Cordell HJ, de Andrade M, Babron MC, Bartlett CW, Beyene J, Bickeböller H, Culverhouse R, Cupples LA, Daw EW, Dupuis J, Falk CT, Ghosh S, Goddard KA, Goode EL, Hauser ER, Martin LJ, Martinez M, North KE, Saccone NL, Schmidt S, Tapper W, Thomas D, Tritchler D, Vieland VJ, Wijsman EM, Wilcox MA, Witte JS, Yang Q, Ziegler A, Almasy L, Maccluer JW. Genetic Analysis Workshop 15: gene expression analysis and approaches to detecting multiple functional loci. BMC Proc. 2007; 1(Supp 1):S1.
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Wu H, Yang Q. American Society of Human Genetics Annual meeting. Comparing Methods for Association Test of Longitudinal or Multivariate Phenotypes. San Diego. 2007.
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Wang, Y, Yang, Q, Rabinowitz, D. 16th Annual Meeting of the International-Genetic-Epidemiology-Society. Unbiased and efficient estimation of the effect of candidate genes on quantitative traits in the presence of population admixture. York. 2007.
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Li G, Yang Q, Krishnan S, Alexander EA, Borkan SC, Schwartz JH. A novel cellular survival factor--the B2 subunit of vacuolar H+-ATPase inhibits apoptosis. Cell Death Differ. 2006 Dec; 13(12):2109-17.View Related Profiles. PMID: 16710359
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Kathiresan S, Yang Q, Larson MG, Lochner A, Tofler GH, Hirschhorn JN, Gabriel SB, O’Donnell CJ. Common Genetic Variation in Five Thrombosis Genes and Relations to Plasma Hemostatic Protein Level and Cardiovascular Disease Risk. Arteriosclerosis, Thrombosis, and Vascular Biology. 2006; 26(6):1405-1412.
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Liu, C; Cupples, LA; Yang, Q, Dupuis J. 15th Annual Meeting of the International-Genetic-Epidemiology-Society. Selection of cases in case-control studies using identity by descent sharing from families with multiple affected siblings. St Petersburg. 2006.
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Kathiresan S, Yang Q, Larson MG, Tofler GH, O'Donnell CJ. 79th Annual Scientific Session of the American-Heart-Association. A genome-wide association study to identify common sequence variants related to five circulating hemostatic factor proteins: The framingham heart study. Chicago. 2006.
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Mosher MJ, Martin LJ, Cupples LA, Yang Q, Dyer TD, Williams JT, North KE. Genotype-by-sex interaction in the regulation of high-density lipoprotein: the Framingham Heart Study. Hum Biol. 2005 Dec; 77(6):773-93. PMID: 16715837
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Yang Q, Guo CY, Cupples LA, Levy D, Wilson PW, Fox CS. Genome-wide search for genes affecting serum uric acid levels: the Framingham Heart Study. Metabolism. 2005 Nov; 54(11):1435-41.View Related Profiles. PMID: 16253630
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Hofmann MA, Yang Q, Harja E, Kedia P, Gregersen PK, Cupples LA, Schmidt AM, Hudson BI. The RAGE Gly82Ser polymorphism is not associated with cardiovascular disease in the Framingham offspring study. Atherosclerosis. 2005 Oct; 182(2):301-5.View Related Profiles. PMID: 16159602
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Kathiresan S, Gabriel SB, Yang Q, Lochner AL, Larson MG, Levy D, Tofler GH, Hirschhorn JN, O'Donnell CJ. Comprehensive survey of common genetic variation at the plasminogen activator inhibitor-1 locus and relations to circulating plasminogen activator inhibitor-1 levels. Circulation. 2005 Sep 20; 112(12):1728-35.View Related Profiles. PMID: 16172282
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Fox CS, Yang Q, Cupples LA, Guo CY, Atwood LD, Murabito JM, Levy D, Mendelsohn ME, Housman DE, Shearman AM. Sex-specific association between estrogen receptor-alpha gene variation and measures of adiposity: the Framingham Heart Study. J Clin Endocrinol Metab. 2005 Nov; 90(11):6257-62.View Related Profiles. PMID: 16144952
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McDermott DH, Yang Q, Kathiresan S, Cupples LA, Massaro JM, Keaney JF, Larson MG, Vasan RS, Hirschhorn JN, O'Donnell CJ, Murphy PM, Benjamin EJ. CCL2 polymorphisms are associated with serum monocyte chemoattractant protein-1 levels and myocardial infarction in the Framingham Heart Study. Circulation. 2005 Aug 23; 112(8):1113-20.View Related Profiles. PMID: 16116069
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Herbert A, Liu C, Karamohamed S, Schiller J, Liu J, Yang Q, Wilson PW, Cupples LA, Meigs JB. The -174 IL-6 GG genotype is associated with a reduced risk of type 2 diabetes mellitus in a family sample from the National Heart, Lung and Blood Institute's Framingham Heart Study. Diabetologia. 2005 Aug; 48(8):1492-5.View Related Profiles. PMID: 15965659
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Li G, Yang Q, Alexander EA, Schwartz JH. Syntaxin 1A has a specific binding site in the H3 domain that is critical for targeting of H+-ATPase to apical membrane of renal epithelial cells. Am J Physiol Cell Physiol. 2005 Sep; 289(3):C665-72.View Related Profiles. PMID: 15872013
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Yang Q, Lai CQ, Parnell L, Cupples LA, Adiconis X, Zhu Y, Wilson PW, Housman DE, Shearman AM, D'Agostino RB, Ordovas JM. Genome-wide linkage analyses and candidate gene fine mapping for HDL3 cholesterol: the Framingham Study. J Lipid Res. 2005 Jul; 46(7):1416-25.View Related Profiles. PMID: 15805549
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Murabito JM, Yang Q, Fox C, Wilson PW, Cupples LA. Heritability of age at natural menopause in the Framingham Heart Study. J Clin Endocrinol Metab. 2005 Jun; 90(6):3427-30.View Related Profiles. PMID: 15769979
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Hudson BI, Hofmann MA, Yang Q, et al. American Heart Association Annual Meeting. The RAGE Gly82Ser polymorphism and cardiovascular disease in the Framingham Offspring Study. Orlando. 2005.
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Zhang F, Yang Q, Cupples LA. International Genetic Epidemiology Society Annual Meeting. Age dependent QTL analysis using Gibbs sampling for random effects models. Park City. 2005.
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Wilk JB, Manning AK, Dupuis J, Cupples LA, Larson MG, Newton-Cheh C, Demissie S, DeStefano AL, Hwang SJ, Liu C, Yang Q, Lunetta KL. International Genetic Epidemiology Society Annual Meeting. No evidence of major population substructure in the Framingham Heart Study. Park City. 2005.
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Guo CY, Cupples LA, Yang Q. International Genetic Epidemiology Society Annual Meeting. Testing informative missingness in family-based linkage and/or association study. Park City. 2005.
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Murabito JM, Yang Q, Fox CS, Cupples LA. Genomewide Linkage Analysis to Age at Natural Menopause in a Community-based Population: The Framingham Heart Study. Fertility and Sterility. 2005; 84:1674-1679.
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Fox CS, Yang Q, Guo CY, Cupples LA, Wilson PW, Levy D, Meigs JB. Genome-wide linkage analysis to urinary microalbuminuria in a community-based sample: the Framingham Heart Study. Kidney Int. 2005 Jan; 67(1):70-4.View Related Profiles. PMID: 15610229
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Fox CS, Yang Q, Cupples LA, Guo CY, Larson MG, Leip EP, Wilson PW, Levy D. Genomewide linkage analysis to serum creatinine, GFR, and creatinine clearance in a community-based population: the Framingham Heart Study. J Am Soc Nephrol. 2004 Sep; 15(9):2457-61.View Related Profiles. PMID: 15339995
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Schlechter BL, Yang Q, Larson PS, Golubeva A, Blanchard RA, de las Morenas A, Rosenberg CL. Quantitative DNA fingerprinting may distinguish new primary breast cancer from disease recurrence. J Clin Oncol. 2004 May 15; 22(10):1830-8.View Related Profiles. PMID: 15143075
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Djoussé L, Knowlton B, Hayden MR, Almqvist EW, Brinkman RR, Ross CA, Margolis RL, Rosenblatt A, Durr A, Dode C, Morrison PJ, Novelletto A, Frontali M, Trent RJ, McCusker E, Gómez-Tortosa E, Mayo Cabrero D, Jones R, Zanko A, Nance M, Abramson RK, Suchowersky O, Paulsen JS, Harrison MB, Yang Q, Cupples LA, Mysore J, Gusella JF, MacDonald ME, Myers RH. Evidence for a modifier of onset age in Huntington disease linked to the HD gene in 4p16. Neurogenetics. 2004 Jun; 5(2):109-14.View Related Profiles. PMID: 15029481; PMCID: PMC1866166
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Fox CS, Yang Q, Guo CY, et al. American Heart Association Annual Meeting. Association between the estrogen receptor alpha gene variation and measures of adiposity: The framingham heart study. Orlando. 2004.
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Kathiresan S, Yang Q, Lochner A, et al. American Heart Association Annual Meeting. Gene-based Haplotypes at the plasminogen activator inhibitor-1 locus are associated with circulating plasminogen activator inhibitor-1 levels. Orlando. 2004.
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Yang Q, Chazaro I, Cui J, Guo CY, Demissie S, Larson M, Atwood LD, Cupples LA, DeStefano AL. Genetic analyses of longitudinal phenotype data: a comparison of univariate methods and a multivariate approach. BMC Genet. 2003; 4 Suppl 1:S29.View Related Profiles. PMID: 14975097; PMCID: PMC1866464
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Cupples LA, Yang Q, Demissie S, Copenhafer D, Levy D. Description of the Framingham Heart Study data for Genetic Analysis Workshop 13. BMC Genet. 2003; 4 Suppl 1:S2.View Related Profiles. PMID: 14975070; PMCID: PMC1866454
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Djoussé L, Knowlton B, Hayden M, Almqvist EW, Brinkman R, Ross C, Margolis R, Rosenblatt A, Durr A, Dode C, Morrison PJ, Novelletto A, Frontali M, Trent RJ, McCusker E, Gómez-Tortosa E, Mayo D, Jones R, Zanko A, Nance M, Abramson R, Suchowersky O, Paulsen J, Harrison M, Yang Q, Cupples LA, Gusella JF, MacDonald ME, Myers RH. Interaction of normal and expanded CAG repeat sizes influences age at onset of Huntington disease. Am J Med Genet A. 2003 Jun 15; 119A(3):279-82.View Related Profiles. PMID: 12784292
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Yang Q, Xu X, Laird N. Power evaluations for family-based tests of association with incomplete parental genotypes. Genetics. 2003 May; 164(1):399-406.View Related Profiles. PMID: 12750350; PMCID: PMC1462535
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Yang Q, Tofler GH, Cupples LA, Larson MG, Feng D, Lindpaintner K, Levy D, D'Agostino RB, O'Donnell CJ. A genome-wide search for genes affecting circulating fibrinogen levels in the Framingham Heart Study. Thromb Res. 2003 Apr 15; 110(1):57-64.View Related Profiles. PMID: 12877910
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McDermott DH, Fong AM, Yang Q, Sechler JM, Cupples LA, Merrell MN, Wilson PW, D'Agostino RB, O'Donnell CJ, Patel DD, Murphy PM. Chemokine receptor mutant CX3CR1-M280 has impaired adhesive function and correlates with protection from cardiovascular disease in humans. J Clin Invest. 2003 Apr; 111(8):1241-50.View Related Profiles. PMID: 12697743; PMCID: PMC152935
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O'Donnell CJ, Yang Q, Lochner A, et al. American Heart Association Annual Meeting. Associations of haplotypes of fibrinogen beta, alpha and gamma chain genes on chromosome 4 with circulating fibrinogen levels in men and women. Orlando. 2003.
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Xu G, Yang Q, Demissie S, et al. American Society of Human Genetics Annual meeting. Haplotype frequency and effect estimations for family-based association analyses. Los Angeles. 2003.
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Yang Q, Atwood LD, Cupples LA. Annual Meeting of International Genetic Epidemiology Society. Multivariate Variance Components Linkage Models for Longitudinal Phenotype Data using Gibbs Sampling Approaches. Redondo Beach. 2003.
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Yang Q, Rabinowitz D, Isasi C, Shea S. Adjusting for confounding due to population admixture when estimating the effect of candidate genes on quantitative traits. Hum Hered. 2000 Jul-Aug; 50(4):227-33. PMID: 10782014; DOI: 10.1159/000022920;
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Rabinowitz D, Yang Q. Testing for age-at-onset anticipation with affected parent-child pairs. Biometrics. 1999 Sep; 55(3):834-8. PMID: 11315014
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Yang Q, Rout MP, Akey CW. Three-dimensional architecture of the isolated yeast nuclear pore complex: functional and evolutionary implications. Mol Cell. 1998 Jan; 1(2):223-34.View Related Profiles. PMID: 9659919