Suryaram Gummuluru | Profiles RNS

Suryaram Gummuluru, PhD

Professor

Boston University School of Medicine

Dept of Microbiology

PhD, University of Rochester
MS, University of Rochester

Websites

	Microbiology Faculty
	Immunology Training Program Faculty

ORCID : 0000-0002-8606-8481

Our research is broadly focused on the role of dendritic cells (DCs) in the initiation and propagation of HIV-1 replication. Since dendritic cells are believed to be the first immune competent cells to encounter virus in the genital mucosa, a thorough understanding of the HIV-DC interactions is of paramount importance. DCs can capture virus particles independently of CD4 and co-receptor complexes, and retain them in an infectious state for an extended period of time. These virus-bearing DCs may then facilitate a more efficient spread of virus to replication-permissive CD4+ T cells. Our recent work has identified a novel glycosphingolipid dependent mechanism of virus attachment to DCs. The fate of the virus particle post-attachment in DCs remains unclear. Virion trafficking within the DC bypasses conventional endocytic organelles, i.e., endosomes and lysosomes. Virus localization within this novel vesicular compartment not only has the potential to protect the invading HIV from being degraded, but also creates a latent reservoir of virus, which could present a major challenge for eradication by antiretroviral therapy. Furthermore, the mechanism of subsequent return of infectious virus particles to the cell surface and the method of subsequent transmission to T cells remains unclear. Current studies utilizing biochemical and microscopic approaches are underway to monitor HIV-1 trafficking and localization in the DC and its subsequent transfer to T cells.

Faculty
Boston University
National Emerging Infectious Disease Lab

Member
Boston University
Genome Science Institute

Graduate Faculty (Primary Mentor of Grad Students)
Boston University School of Medicine, Graduate Medical Sciences

BU Research
NIH RePORTER Research

Synergistic Mechanisms of chronic Innate Immune Activation in Microglia by opiates and HIV Infection
07/15/2020 - 04/30/2025 (Multi-PI)
PI: Suryaram Gummuluru, PhD
NIH/National Institute on Drug Abuse
1R01DA051889-01

Providence/Boston Center for AIDS Research (CFAR): Core Support (Cores A, B, E, G, K, SWG)
07/01/2018 - 06/30/2023 (PI of Sub-Project / SP)
The Miriam Hospital NIH NIAID
5P30AI042853-22

Persistent HIV expression induced type 1 IFN responses and inflammaging
08/01/2018 - 04/30/2023 (PI)
NIH/National Institute on Aging
5R01AG060890-03

Signals that establish and maintain HIV latency
05/08/2018 - 04/30/2023 (Subcontract PI)
Boston Medical Center Corporation NIH NIAID
R01AI138960-01

GM3 Nanoparticles for Sustained Delivery of Anti-Retrovirals to Lymphatic Tissues
11/08/2017 - 10/31/2022 (Multi-PI)
PI: Suryaram Gummuluru, PhD
NIH/National Institute of Allergy & Infectious Diseases
5R01AI132111-03

Mechanism of Cell-Associated HIV-1 Transmission
12/01/2015 - 11/30/2020 (PI)
NIH/National Institute of Allergy & Infectious Diseases
5R01AI064099-15

Engineering a 3D human neurovascular unit for investigating and countering neuroinflammatory mechanisms of HIV
09/30/2017 - 08/31/2020 (Multi-PI)
PI: Suryaram Gummuluru, PhD
NIH/National Institute of Neurological Disorders & Stroke
5R21NS105837-02

CD1a vaginal dendritic cells and HIV-1 acquisition in the female genital tract
05/15/2015 - 04/30/2020 (Subcontract PI)
Boston Medical Center Corporation NIH NIAID
5R01AI122209-05

Lifespan/Tufts/brown Center for AIDS Research (CFAR): Core K, Core B, and Core G
07/01/2016 - 06/30/2018 (PI of Sub-Project / SP)
The Miriam Hospital NIH NIAID
3P30AI042853-19S1

A novel microfluidic system to investigate mechanism of HIV-induced disruption of BBB function
01/01/2017 - 12/31/2017 (Subcontract Co-PI)
The Miriam Hospital NIH NIAID
4P30AI042853-19

Showing 10 of 13 results. Show All Results

Title

Yr	Title	Project-Sub Proj	Pubs
2021	GM3 Nanoparticles for Sustained Delivery of Anti-Retrovirals to Lymphatic Tissues	5R01AI132111-04	3
2020	Single Cell Transcriptomics of the Opioid Use Disorder and HIV Syndemic in the Human Brain	7UM1DA051411-02
2020	Single cell transcriptomics of the opioid use disorder and HIV syndemic in the human brain	1UM1DA051411-01
2020	Synergistic Mechanisms of chronic Innate Immune Activation in Microglia by Opiates and HIV Infection	1R01DA051889-01
2020	Persistent HIV expression induced type I IFN responses and inflammaging	5R01AG060890-03	2
2020	GM3 Nanoparticles for Sustained Delivery of Anti-Retrovirals to Lymphatic Tissues	5R01AI132111-03	3
2020	Mechanism of cell-associated HIV-1 transmission	5R01AI064099-15	34
2019	Persistent HIV expression induced type I IFN responses and inflammaging	5R01AG060890-02	2
2019	GM3 Nanoparticles for Sustained Delivery of Anti-Retrovirals to Lymphatic Tissues	5R01AI132111-02	3
2019	Mechanism of cell-associated HIV-1 transmission	5R01AI064099-14	34

Showing 10 of 31 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis Copy PMIDs To Clipboard

Akiyama H, Jalloh S, Park S, Lei M, Mostoslavsky G, Gummuluru S. Expression of HIV-1 Intron-Containing RNA in Microglia Induces Inflammatory Responses. J Virol. 2020 Dec 09.View Related Profiles.

Mostoslavsky, Gustavo
Akiyama, Hisashi
Gummuluru, Suryaram

PMID: 33298546

Eshaghi B, Alsharif N, An X, Akiyama H, Brown KA, Gummuluru S, Reinhard BM. Stiffness of HIV-1 Mimicking Polymer Nanoparticles Modulates Ganglioside-Mediated Cellular Uptake and Trafficking. Adv Sci (Weinh). 2020 Sep; 7(18):2000649.View Related Profiles.

Akiyama, Hisashi
Gummuluru, Suryaram

PMID: 32999830

Akiyama H, Gummuluru S. HIV-1 Persistence and Chronic Induction of Innate Immune Responses in Macrophages. Viruses. 2020 06 30; 12(7).View Related Profiles.

Akiyama, Hisashi
Gummuluru, Suryaram

PMID: 32630058

Amraie R, Napoleon MA, Yin W, Berrigan J, Suder E, Zhao G, Olejnik J, Gummuluru S, Muhlberger E, Chitalia V, Rahimi N. CD209L/L-SIGN and CD209/DC-SIGN act as receptors for SARS-CoV-2 and are differentially expressed in lung and kidney epithelial and endothelial cells. bioRxiv. 2020 Jun 23.View Related Profiles.

Muhlberger, Elke
Olejnik, Judith
Rahimi, Nader
Gummuluru, Suryaram
Chitalia, Vipul

PMID: 32607506; DOI: 10.1101/2020.06.22.165803;

Wooten AK, Shenoy AT, Arafa EI, Akiyama H, Martin IMC, Jones MR, Quinton LJ, Gummuluru S, Bai G, Mizgerd JP. Unique Roles for Streptococcus pneumoniae Phosphodiesterase 2 in Cyclic di-AMP Catabolism and Macrophage Responses. Front Immunol. 2020; 11:554.View Related Profiles.

Wooten, Alicia
Shenoy, Anukul
Akiyama, Hisashi
Mizgerd, Joseph
Quinton, Lee
Jones, Matthew
Gummuluru, Suryaram

PMID: 32300347

Nodder SB, Gummuluru S. Illuminating the Role of Vpr in HIV Infection of Myeloid Cells. Front Immunol. 2019; 10:1606. PMID: 31396206

Gagne M, Michaels D, Schiralli Lester GM, Gummuluru S, Wong WW, Henderson AJ. Strength of T cell signaling regulates HIV-1 replication and establishment of latency. PLoS Pathog. 2019 05; 15(5):e1007802.View Related Profiles.

Henderson, Andrew
Schiralli Lester, Gillian
Gagne, Matthew
Gummuluru, Suryaram

PMID: 31116788

Li M, Waheed AA, Yu J, Zeng C, Chen HY, Zheng YM, Feizpour A, Reinhard BM, Gummuluru S, Lin S, Freed EO, Liu SL. TIM-mediated inhibition of HIV-1 release is antagonized by Nef but potentiated by SERINC proteins. Proc Natl Acad Sci U S A. 2019 03 19; 116(12):5705-5714. PMID: 30842281

Xu F, Bandara A, Akiyama H, Eshaghi B, Stelter D, Keyes T, Straub JE, Gummuluru S, Reinhard BM. Membrane-wrapped nanoparticles probe divergent roles of GM3 and phosphatidylserine in lipid-mediated viral entry pathways. Proc Natl Acad Sci U S A. 2018 09 25; 115(39):E9041-E9050.View Related Profiles.

Akiyama, Hisashi
Straub, John
Gummuluru, Suryaram
Keyes, Tom

PMID: 30190430

Akiyama H, Miller CM, Ettinger CR, Belkina AC, Snyder-Cappione JE, Gummuluru S. HIV-1 intron-containing RNA expression induces innate immune activation and T cell dysfunction. Nat Commun. 2018 08 27; 9(1):3450.View Related Profiles.

Belkina, Anna
Miller, Caitlin
Akiyama, Hisashi
Snyder-Cappione , Jennifer
Gummuluru, Suryaram

PMID: 30150664

Showing 10 of 51 results. Show More

Pena-Cruz V, Agosto LM, Akiyama H, Olson A, Moreau Y, Larrieux JR, Henderson A, Gummuluru S, Sagar M. HIV-1 replicates and persists in vaginal epithelial dendritic cells. J Clin Invest. 2018 08 01; 128(8):3439-3444.View Related Profiles.

Henderson, Andrew
Akiyama, Hisashi
Larrieux, Jean-Robert
Agosto Vazquez, Luis
Sagar, Manish
Gummuluru, Suryaram

PMID: 29723162

Akiyama H, Ramirez NP, Gibson G, Kline C, Watkins S, Ambrose Z, Gummuluru S. Interferon-Inducible CD169/Siglec1 Attenuates Anti-HIV-1 Effects of Alpha Interferon. J Virol. 2017 Nov 01; 91(21).View Related Profiles.

Akiyama, Hisashi
Gummuluru, Suryaram

PMID: 28794041

Feizpour A, Stelter D, Wong C, Akiyama H, Gummuluru S, Keyes T, Reinhard BM. Membrane Fluidity Sensing on the Single Virus Particle Level with Plasmonic Nanoparticle Transducers. ACS Sens. 2017 Oct 27; 2(10):1415-1423.View Related Profiles.

Reinhard, Bjorn
Akiyama, Hisashi
Gummuluru, Suryaram
Keyes, Tom

PMID: 28933537

Nazari M, Xi M, Lerch S, Alizadeh MH, Ettinger C, Akiyama H, Gillespie C, Gummuluru S, Erramilli S, Reinhard BM. Plasmonic Enhancement of Selective Photonic Virus Inactivation. Sci Rep. 2017 09 20; 7(1):11951.View Related Profiles.

Reinhard, Bjorn
Akiyama, Hisashi
Gummuluru, Suryaram

PMID: 28931903

Ruedas JB, Ladner JT, Ettinger CR, Gummuluru S, Palacios G, Connor JH. Spontaneous Mutation at Amino Acid 544 of the Ebola Virus Glycoprotein Potentiates Virus Entry and Selection in Tissue Culture. J Virol. 2017 Aug 01; 91(15).View Related Profiles.

Connor, John
Gummuluru, Suryaram

PMID: 28539437

Kozlowski E, Wasserman GA, Morgan M, O'Carroll D, Ramirez NP, Gummuluru S, Rah JY, Gower AC, Ieong M, Quinton LJ, Mizgerd JP, Jones MR. The RNA uridyltransferase Zcchc6 is expressed in macrophages and impacts innate immune responses. PLoS One. 2017; 12(6):e0179797.View Related Profiles.

Gower, Adam
Kozlowski, Elyse
Wasserman, Gregory
Mizgerd, Joseph
Quinton, Lee
Jones, Matthew
Ieong, Michael
Gummuluru, Suryaram

PMID: 28665939

Miller CM, Akiyama H, Agosto LM, Emery A, Ettinger CR, Swanstrom RI, Henderson AJ, Gummuluru S. Virion-Associated Vpr Alleviates a Postintegration Block to HIV-1 Infection of Dendritic Cells. J Virol. 2017 Jul 01; 91(13).View Related Profiles.

Henderson, Andrew
Miller, Caitlin
Akiyama, Hisashi
Agosto Vazquez, Luis
Gummuluru, Suryaram

PMID: 28424288; DOI: 10.1128/JVI.00051-17;

Ahi YS, Zhang S, Thappeta Y, Denman A, Feizpour A, Gummuluru S, Reinhard B, Muriaux D, Fivash MJ, Rein A. Functional Interplay Between Murine Leukemia Virus Glycogag, Serinc5, and Surface Glycoprotein Governs Virus Entry, with Opposite Effects on Gammaretroviral and Ebolavirus Glycoproteins. MBio. 2016 Nov 22; 7(6). PMID: 27879338; DOI: 10.1128/mBio.01985-16;

Kijewski SD, Akiyama H, Feizpour A, Miller CM, Ramirez NG, Reinhard BM, Gummuluru S. Access of HIV-2 to CD169-dependent dendritic cell-mediated trans infection pathway is attenuated. Virology. 2016 Oct; 497:328-36.View Related Profiles.

Reinhard, Bjorn
Miller, Caitlin
Akiyama, Hisashi
Gummuluru, Suryaram
Kijewski, Suzanne

PMID: 27521724; PMCID: PMC5026622; DOI: 10.1016/j.virol.2016.07.029;

Xu F, Reiser M, Yu X, Gummuluru S, Wetzler L, Reinhard BM. Lipid-Mediated Targeting with Membrane-Wrapped Nanoparticles in the Presence of Corona Formation. ACS Nano. 2016 Jan 26; 10(1):1189-200.View Related Profiles.

Reinhard, Bjorn
Wetzler, Lee
Reiser, Michael
Gummuluru, Suryaram

PMID: 26720275; PMCID: PMC4842014; DOI: 10.1021/acsnano.5b06501;

Yu X, Xu F, Ramirez NG, Kijewski SD, Akiyama H, Gummuluru S, Reinhard BM. Dressing up Nanoparticles: A Membrane Wrap to Induce Formation of the Virological Synapse. ACS Nano. 2015; 9(4):4182-92.View Related Profiles.

Reinhard, Bjorn
Akiyama, Hisashi
Gummuluru, Suryaram
Kijewski, Suzanne

PMID: 25853367; PMCID: PMC4423798; DOI: 10.1021/acsnano.5b00415;

Akiyama H, Ramirez NG, Gudheti MV, Gummuluru S. CD169-mediated trafficking of HIV to plasma membrane invaginations in dendritic cells attenuates efficacy of anti-gp120 broadly neutralizing antibodies. PLoS Pathog. 2015 Mar; 11(3):e1004751.View Related Profiles.

Akiyama, Hisashi
Gummuluru, Suryaram

PMID: 25760631; PMCID: PMC4356592; DOI: 10.1371/journal.ppat.1004751;

Kijewski SD, Gummuluru S. A mechanistic overview of dendritic cell-mediated HIV-1 trans infection: the story so far. Future Virol. 2015 Mar; 10(3):257-269.View Related Profiles.

Gummuluru, Suryaram
Kijewski, Suzanne

PMID: 26213560

Gummuluru S, Pina Ramirez NG, Akiyama H. CD169-dependent cell-associated HIV-1 transmission: a driver of virus dissemination. J Infect Dis. 2014 Dec 15; 210 Suppl 3:S641-7.View Related Profiles.

Akiyama, Hisashi
Gummuluru, Suryaram

PMID: 25414418; PMCID: PMC4303078; DOI: 10.1093/infdis/jiu442;

Feizpour A, Yu X, Akiyama H, Miller CM, Edmans E, Gummuluru S, Reinhard BM. Quantifying lipid contents in enveloped virus particles with plasmonic nanoparticles. Small. 2015 Apr; 11(13):1592-602.View Related Profiles.

Reinhard, Bjorn
Miller, Caitlin
Akiyama, Hisashi
Gummuluru, Suryaram

PMID: 25382201; PMCID: PMC4447146; DOI: 10.1002/smll.201402184;

Colvin TA, Gabai VL, Gong J, Calderwood SK, Li H, Gummuluru S, Matchuk ON, Smirnova SG, Orlova NV, Zamulaeva IA, Garcia-Marcos M, Li X, Young ZT, Rauch JN, Gestwicki JE, Takayama S, Sherman MY. Hsp70-Bag3 interactions regulate cancer-related signaling networks. Cancer Res. 2014 Sep 1; 74(17):4731-40.View Related Profiles.

Gong, Jianlin
Sherman, Michael
Garcia-Marcos, Mikel
Gummuluru, Suryaram
Colvin, Teresa
Gabai, Vladimir

PMID: 24994713; PMCID: PMC4174322; DOI: 10.1158/0008-5472.CAN-14-0747;

Yu X, Feizpour A, Ramirez NG, Wu L, Akiyama H, Xu F, Gummuluru S, Reinhard BM. Glycosphingolipid-functionalized nanoparticles recapitulate CD169-dependent HIV-1 uptake and trafficking in dendritic cells. Nat Commun. 2014; 5:4136.View Related Profiles.

Reinhard, Bjorn
Akiyama, Hisashi
Gummuluru, Suryaram

PMID: 24947940; PMCID: PMC4109413; DOI: 10.1038/ncomms5136;

Akiyama H, Miller C, Patel HV, Hatch SC, Archer J, Ramirez NG, Gummuluru S. Virus particle release from glycosphingolipid-enriched microdomains is essential for dendritic cell-mediated capture and transfer of HIV-1 and henipavirus. J Virol. 2014 Aug; 88(16):8813-25.View Related Profiles.

Miller, Caitlin
Akiyama, Hisashi
Gummuluru, Suryaram

PMID: 24872578; PMCID: PMC4136256; DOI: 10.1128/JVI.00992-14;

Puryear WB, Akiyama H, Geer SD, Ramirez NP, Yu X, Reinhard BM, Gummuluru S. Interferon-inducible mechanism of dendritic cell-mediated HIV-1 dissemination is dependent on Siglec-1/CD169. PLoS Pathog. 2013; 9(4):e1003291.View Related Profiles.

Reinhard, Bjorn
Akiyama, Hisashi
Gummuluru, Suryaram
Kijewski, Suzanne
Puryear, Wendy

PMID: 23593001; PMCID: PMC3623718; DOI: 10.1371/journal.ppat.1003291;

Puryear WB, Gummuluru S. Role of glycosphingolipids in dendritic cell-mediated HIV-1 trans-infection. Adv Exp Med Biol. 2013; 762:131-53.View Related Profiles.

Gummuluru, Suryaram
Puryear, Wendy

PMID: 22975874; PMCID: PMC3686569; DOI: 10.1007/978-1-4614-4433-6_5;

Schiralli Lester GM, Akiyama H, Evans E, Singh J, Gummuluru S, Henderson AJ. Interleukin 2-inducible T cell kinase (ITK) facilitates efficient egress of HIV-1 by coordinating Gag distribution and actin organization. Virology. 2013 Feb 5; 436(1):235-43.View Related Profiles.

Henderson, Andrew
Schiralli Lester, Gillian
Akiyama, Hisashi
Gummuluru, Suryaram

PMID: 23260110; PMCID: PMC3598624; DOI: 10.1016/j.virol.2012.11.015;

Waheed AA, Brass AL, Gummuluru S, Tachedjian G. Host-pathogen interactions of retroviruses. Mol Biol Int. 2012; 2012:648512. PMID: 23150826; PMCID: PMC3488407; DOI: 10.1155/2012/648512;

Puryear WB, Yu X, Ramirez NP, Reinhard BM, Gummuluru S. HIV-1 incorporation of host-cell-derived glycosphingolipid GM3 allows for capture by mature dendritic cells. Proc Natl Acad Sci U S A. 2012 May 8; 109(19):7475-80.View Related Profiles.

Reinhard, Bjorn
Gummuluru, Suryaram
Puryear, Wendy

PMID: 22529395; PMCID: PMC3358844; DOI: 10.1073/pnas.1201104109;

Sagar M, Akiyama H, Etemad B, Ramirez N, Freitas I, Gummuluru S. Transmembrane domain membrane proximal external region but not surface unit-directed broadly neutralizing HIV-1 antibodies can restrict dendritic cell-mediated HIV-1 trans-infection. J Infect Dis. 2012 Apr 15; 205(8):1248-57.View Related Profiles.

Etemad, Behzad
Akiyama, Hisashi
Sagar, Manish
Gummuluru, Suryaram

PMID: 22396600; PMCID: PMC3308909; DOI: 10.1093/infdis/jis183;

Hanley TM, Blay Puryear W, Gummuluru S, Viglianti GA. PPARgamma and LXR signaling inhibit dendritic cell-mediated HIV-1 capture and trans-infection. PLoS Pathog. 2010; 6:e1000981.View Related Profiles.

Viglianti, Gregory
Gummuluru, Suryaram

PMID: 20617179; PMCID: PMC2895661; DOI: 10.1371/journal.ppat.1000981;

Hatch SC, Archer J, Gummuluru S. Glycosphingolipid composition of human immunodeficiency virus type 1 (HIV-1) particles is a crucial determinant for dendritic cell-mediated HIV-1 trans-infection. J Virol. 2009 Apr; 83(8):3496-506. PMID: 19193785; PMCID: PMC2663285; DOI: 10.1128/JVI.02249-08;

Izquierdo-Useros N, Naranjo-Gómez M, Archer J, Hatch SC, Erkizia I, Blanco J, Borràs FE, Puertas MC, Connor JH, Fernández-Figueras MT, Moore L, Clotet B, Gummuluru S, Martinez-Picado J. Capture and transfer of HIV-1 particles by mature dendritic cells converges with the exosome-dissemination pathway. Blood. 2009 Mar 19; 113(12):2732-41.View Related Profiles.

Connor, John
Gummuluru, Suryaram

PMID: 18945959; PMCID: PMC2661860; DOI: 10.1182/blood-2008-05-158642;

Nguyen DH, Gummuluru S, Hu J. Deamination-independent inhibition of hepatitis B virus reverse transcription by APOBEC3G. J Virol. 2007 May; 81(9):4465-72. PMID: 17314171; PMCID: PMC1900192

Wiley RD, Gummuluru S. Immature dendritic cell-derived exosomes can mediate HIV-1 trans infection. Proc Natl Acad Sci U S A. 2006 Jan 17; 103(3):738-43. PMID: 16407131; PMCID: PMC1334656

Gummuluru S, Rogel M, Stamatatos L, Emerman M. Binding of human immunodeficiency virus type 1 to immature dendritic cells can occur independently of DC-SIGN and mannose binding C-type lectin receptors via a cholesterol-dependent pathway. J Virol. 2003 Dec; 77(23):12865-74. PMID: 14610207; PMCID: PMC262553

Gummuluru S, KewalRamani VN, Emerman M. Dendritic cell-mediated viral transfer to T cells is required for human immunodeficiency virus type 1 persistence in the face of rapid cell turnover. J Virol. 2002 Nov; 76(21):10692-701. PMID: 12368311; PMCID: PMC136613

Gummuluru S, Emerman M. Advances in HIV molecular biology. AIDS. 2002; 16 Suppl 4:S17-23. PMID: 12698995

Gummuluru S, Kinsey CM, Emerman M. An in vitro rapid-turnover assay for human immunodeficiency virus type 1 replication selects for cell-to-cell spread of virus. J Virol. 2000 Dec; 74(23):10882-91. PMID: 11069982; PMCID: PMC113167

Gummuluru S, Emerman M. Cell cycle- and Vpr-mediated regulation of human immunodeficiency virus type 1 expression in primary and transformed T-cell lines. J Virol. 1999 Jul; 73(7):5422-30. PMID: 10364289; PMCID: PMC112598

Whetter L, Novembre FJ, Saucier M, Gummuluru S, Dewhurst S. Costimulatory pathways in lymphocyte proliferation induced by the simian immunodeficiency virus SIVsmmPBj14. J Virol. 1998 Jul; 72(7):6155-8. PMID: 9621081; PMCID: PMC110423

Krajewski S, James HJ, Ross J, Blumberg BM, Epstein LG, Gendelman HE, Gummuluru S, Dewhurst S, Sharer LR, Reed JC, Gelbard HA. Expression of pro- and anti-apoptosis gene products in brains from paediatric patients with HIV-1 encephalitis. Neuropathol Appl Neurobiol. 1997 Jun; 23(3):242-53. PMID: 9223134

Gummuluru S, Novembre FJ, Lewis M, Gelbard HA, Dewhurst S. Apoptosis correlates with immune activation in intestinal lymphoid tissue from macaques acutely infected by a highly enteropathic simian immunodeficiency virus, SIVsmmPBj14. Virology. 1996 Nov 1; 225(1):21-32. PMID: 8918530

Gummuluru S, Novembre FJ, Seshi B, Dewhurst S. SIVsmmPBj14 induces expression of a mucosal integrin on macaque lymphocytes. Virology. 1996 Jan 1; 215(1):97-100. PMID: 8553590

van Loon NM, Gummuluru S, Sherwood DJ, Marentes R, Hall CB, Dewhurst S. Direct sequence analysis of human herpesvirus 6 (HHV-6) sequences from infants and comparison of HHV-6 sequences from mother/infant pairs. Clin Infect Dis. 1995 Oct; 21(4):1017-9. PMID: 8645791

Talley AK, Dewhurst S, Perry SW, Dollard SC, Gummuluru S, Fine SM, New D, Epstein LG, Gendelman HE, Gelbard HA. Tumor necrosis factor alpha-induced apoptosis in human neuronal cells: protection by the antioxidant N-acetylcysteine and the genes bcl-2 and crmA. Mol Cell Biol. 1995 May; 15(5):2359-66. PMID: 7739519; PMCID: PMC230464

Dollard SC, Gummuluru S, Tsang S, Fultz PN, Dewhurst S. Enhanced responsiveness to nuclear factor kappa B contributes to the unique phenotype of simian immunodeficiency virus variant SIVsmmPBj14. J Virol. 1994 Dec; 68(12):7800-9. PMID: 7966569; PMCID: PMC237241

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 51 publications over 23 distinct years, with a maximum of 6 publications in 2017