Keywords
Last Name

Jianlin Gong, MD

TitleProfessor
InstitutionBoston University School of Medicine
DepartmentMedicine
DivisionHematology & Medical Oncology
Address650 Albany St Evans Biomed Research Ctr
Boston MA 02118
Phone(617) 414-1715
ORCID ORCID Icon0000-0003-0910-014X
Other Positions
TitleGraduate Faculty (Primary Mentor of Grad Students)
InstitutionBoston University School of Medicine, Division of Graduate Medical Sciences

 Research Expertise & Professional Interests
I have expertise in generation of dendritic cells (DC), development of tumor vaccine including DC-tumor cell fusion and heat shock proteins, animal models for translational research and preclinical research using human cancer samples.

 Self-Described Keywords
  • Cytotoxic T lymphocytes
  • DC-tumor cell fusion
  • Dendritic cells (DC)
  • Heat shock proteins
 Publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
List All   |   Timeline
  1. Calderwood SK, Gong J, Murshid A. Extracellular HSPs: The Complicated Roles of Extracellular HSPs in Immunity. Front Immunol. 2016; 7:159. PMID: 27199984.
    View in: PubMed
  2. Calderwood SK, Gong J. Heat Shock Proteins Promote Cancer: It's a Protection Racket. Trends Biochem Sci. 2016 Apr; 41(4):311-23. PMID: 26874923.
    View in: PubMed
  3. Koido S, Homma S, Kan S, Takakura K, Namiki Y, Kobayashi H, Ito Z, Uchiyama K, Kajihara M, Arihiro S, Arakawa H, Okamoto M, Ohkusa T, Gong J, Tajiri H. Induction of antigen-specific cytotoxic T lymphocytes by fusion cells generated from allogeneic plasmacytoid dendritic and tumor cells. Int J Oncol. 2015 Jun; 46(6):2679. PMID: 25846893.
    View in: PubMed
  4. Murshid A, Gong J, Prince T, Borges TJ, Calderwood SK. Scavenger receptor SREC-I mediated entry of TLR4 into lipid microdomains and triggered inflammatory cytokine release in RAW 264.7 cells upon LPS activation. PLoS One. 2015; 10(4):e0122529. PMID: 25836976.
    View in: PubMed
  5. Takakura K, Kajihara M, Ito Z, Ohkusa T, Gong J, Koido S. Dendritic-tumor fusion cells in cancer immunotherapy. Discov Med. 2015 Mar; 19(104):169-74. PMID: 25828520.
    View in: PubMed
  6. Gong J, Weng D, Eguchi T, Murshid A, Sherman MY, Song B, Calderwood SK. Targeting the hsp70 gene delays mammary tumor initiation and inhibits tumor cell metastasis. Oncogene. 2015 Oct; 34(43):5460-71. PMID: 25659585.
    View in: PubMed
  7. Koido S, Gong J. Cell fusion between dendritic cells and whole tumor cells. Methods Mol Biol. 2015; 1313:185-91. PMID: 25947665.
    View in: PubMed
  8. Murshid A, Gong J, Ahmad R, Borges TJ, Calderwood SK. Scavenger receptor SREC-I promotes double stranded RNA-mediated TLR3 activation in human monocytes. Immunobiology. 2015 Jun; 220(6):823-32. PMID: 25641411.
    View in: PubMed
  9. Koido S, Kan S, Yoshida K, Yoshizaki S, Takakura K, Namiki Y, Tsukinaga S, Odahara S, Kajihara M, Okamoto M, Ito M, Yusa S, Gong J, Sugiyama H, Ohkusa T, Homma S, Tajiri H. Immunogenic modulation of cholangiocarcinoma cells by chemoimmunotherapy. Anticancer Res. 2014 Nov; 34(11):6353-61. PMID: 25368235.
    View in: PubMed
  10. Murshid A, Gong J, Calderwood SK. Hsp90-peptide complexes stimulate antigen presentation through the class II pathway after binding scavenger receptor SREC-I. Immunobiology. 2014 Dec; 219(12):924-31. PMID: 25155057.
    View in: PubMed
  11. Koido S, Enomoto Y, Apostolopoulos V, Gong J. Tumor regression by CD4 T-cells primed with dendritic/tumor fusion cell vaccines. Anticancer Res. 2014 Aug; 34(8):3917-24. PMID: 25075013.
    View in: PubMed
  12. Koido S, Homma S, Okamoto M, Takakura K, Mori M, Yoshizaki S, Tsukinaga S, Odahara S, Koyama S, Imazu H, Uchiyama K, Kajihara M, Arakawa H, Misawa T, Toyama Y, Yanagisawa S, Ikegami M, Kan S, Hayashi K, Komita H, Kamata Y, Ito M, Ishidao T, Yusa S, Shimodaira S, Gong J, Sugiyama H, Ohkusa T, Tajiri H. Treatment with chemotherapy and dendritic cells pulsed with multiple Wilms' tumor 1 (WT1)-specific MHC class I/II-restricted epitopes for pancreatic cancer. Clin Cancer Res. 2014 Aug 15; 20(16):4228-39. PMID: 25056373.
    View in: PubMed
  13. Colvin TA, Gabai VL, Gong J, Calderwood SK, Li H, Gummuluru S, Matchuk ON, Smirnova SG, Orlova NV, Zamulaeva IA, Garcia-Marcos M, Li X, Young ZT, Rauch JN, Gestwicki JE, Takayama S, Sherman MY. Hsp70-Bag3 interactions regulate cancer-related signaling networks. Cancer Res. 2014 Sep 1; 74(17):4731-40. PMID: 24994713.
    View in: PubMed
  14. Chou SD, Murshid A, Eguchi T, Gong J, Calderwood SK. HSF1 regulation of ß-catenin in mammary cancer cells through control of HuR/elavL1 expression. Oncogene. 2015 Apr 23; 34(17):2178-88. PMID: 24954509.
    View in: PubMed
  15. Koido S, Homma S, Kan S, Takakura K, Namiki Y, Kobayashi H, Ito Z, Uchiyama K, Kajihara M, Arihiro S, Arakawa H, Okamoto M, Ohkusa T, Gong J, Tajiri H. Induction of antigen-specific cytotoxic T lymphocytes by fusion cells generated from allogeneic plasmacytoid dendritic and tumor cells. Int J Oncol. 2014 Jul; 45(1):470-8. PMID: 24819411.
    View in: PubMed
  16. Koido S, Ohkusa T, Homma S, Namiki Y, Takakura K, Saito K, Ito Z, Kobayashi H, Kajihara M, Uchiyama K, Arihiro S, Arakawa H, Okamoto M, Gong J, Tajiri H. Immunotherapy for colorectal cancer. World J Gastroenterol. 2013 Dec 14; 19(46):8531-42. PMID: 24379570.
    View in: PubMed
  17. Koido S, Homma S, Okamoto M, Namiki Y, Takakura K, Uchiyama K, Kajihara M, Arihiro S, Imazu H, Arakawa H, Kan S, Komita H, Kamata Y, Ito M, Ohkusa T, Gong J, Tajiri H. Strategies to improve the immunogenicity of anticancer vaccines based on dendritic cell/malignant cell fusions. Oncoimmunology. 2013 Sep 1; 2(9):e25994. PMID: 24228229.
    View in: PubMed
  18. Koido S, Homma S, Okamoto M, Namiki Y, Kan S, Takakura K, Kajihara M, Uchiyama K, Hara E, Ohkusa T, Gong J, Tajiri H. Improved immunogenicity of fusions between ethanol-treated cancer cells and dendritic cells exposed to dual TLR stimulation. Oncoimmunology. 2013 Aug 1; 2(8):e25375. PMID: 24167764.
    View in: PubMed
  19. Weng D, Song B, Koido S, Calderwood SK, Gong J. Immunotherapy of radioresistant mammary tumors with early metastasis using molecular chaperone vaccines combined with ionizing radiation. J Immunol. 2013 Jul 15; 191(2):755-63. PMID: 23772032.
    View in: PubMed
  20. Koido S, Homma S, Okamoto M, Namiki Y, Takakura K, Takahara A, Odahara S, Tsukinaga S, Yukawa T, Mitobe J, Matsudaira H, Nagatsuma K, Kajihara M, Uchiyama K, Arihiro S, Imazu H, Arakawa H, Kan S, Hayashi K, Komita H, Kamata Y, Ito M, Hara E, Ohkusa T, Gong J, Tajiri H. Augmentation of antitumor immunity by fusions of ethanol-treated tumor cells and dendritic cells stimulated via dual TLRs through TGF-ß1 blockade and IL-12p70 production. PLoS One. 2013; 8(5):e63498. PMID: 23717436.
    View in: PubMed
  21. Calderwood SK, Gong J, Stevenson MA, Murshid A. Cellular and molecular chaperone fusion vaccines: targeting resistant cancer cell populations. Int J Hyperthermia. 2013 Aug; 29(5):376-9. PMID: 23682824.
    View in: PubMed
  22. Koido S, Homma S, Okamoto M, Namiki Y, Takakura K, Uchiyama K, Kajihara M, Arihiro S, Imazu H, Arakawa H, Kan S, Komita H, Ito M, Ohkusa T, Gong J, Tajiri H. Fusions between dendritic cells and whole tumor cells as anticancer vaccines. Oncoimmunology. 2013 May 1; 2(5):e24437. PMID: 23762810.
    View in: PubMed
  23. Koido S, Homma S, Okamoto M, Namiki Y, Takakura K, Uchiyama K, Kajihara M, Ohkusa T, Gong J, Tajiri H. The combination of TLR2 and TLR4 agonists promotes the immunogenicity of dendritic cell/cancer cell fusions. Oncoimmunology. 2013 Jul 1; 2(7):e24660. PMID: 24073361.
    View in: PubMed
  24. Koido S, Homma S, Okamoto M, Namiki Y, Takakura K, Takahara A, Odahara S, Tsukinaga S, Yukawa T, Mitobe J, Matsudaira H, Nagatsuma K, Uchiyama K, Kajihara M, Arihiro S, Imazu H, Arakawa H, Kan S, Komita H, Ito M, Ohkusa T, Gong J, Tajiri H. Combined TLR2/4-activated dendritic/tumor cell fusions induce augmented cytotoxic T lymphocytes. PLoS One. 2013; 8(3):e59280. PMID: 23555011.
    View in: PubMed
  25. Koido S, Gong J. Characterization of structure and direct antigen presentation by dendritic/tumor-fused cells as cancer vaccines. Anticancer Res. 2013 Feb; 33(2):347-54. PMID: 23393323.
    View in: PubMed
  26. Murshid A, Gong J, Calderwood SK. Purification, preparation, and use of chaperone-peptide complexes for tumor immunotherapy. Methods Mol Biol. 2013; 960:209-17. PMID: 23329490.
    View in: PubMed
  27. Ghosh SK, Uchida M, Yoo B, Ross AW, Gendler SJ, Gong J, Moore A, Medarova Z. Targeted imaging of breast tumor progression and therapeutic response in a human uMUC-1 expressing transgenic mouse model. Int J Cancer. 2013 Apr 15; 132(8):1860-7. PMID: 23015160.
    View in: PubMed
  28. Chou SD, Prince T, Gong J, Calderwood SK. mTOR is essential for the proteotoxic stress response, HSF1 activation and heat shock protein synthesis. PLoS One. 2012; 7(6):e39679. PMID: 22768106.
    View in: PubMed
  29. Calderwood SK, Murshid A, Gong J. Heat shock proteins: conditional mediators of inflammation in tumor immunity. Front Immunol. 2012; 3:75. PMID: 22566956.
    View in: PubMed
  30. Calderwood SK, Gong J. Molecular chaperones in mammary cancer growth and breast tumor therapy. J Cell Biochem. 2012 Apr; 113(4):1096-103. PMID: 22105880.
    View in: PubMed
  31. Murshid A, Gong J, Calderwood SK. The role of heat shock proteins in antigen cross presentation. Front Immunol. 2012; 3:63. PMID: 22566944.
    View in: PubMed
  32. Weng D, Penzner JH, Song B, Koido S, Calderwood SK, Gong J. Metastasis is an early event in mouse mammary carcinomas and is associated with cells bearing stem cell markers. Breast Cancer Res. 2012; 14(1):R18. PMID: 22277639.
    View in: PubMed
  33. Koido S, Homma S, Takahara A, Namiki Y, Komita H, Uchiyama K, Ito M, Gong J, Ohkusa T, Tajiri H. Immunotherapy synergizes with chemotherapy targeting pancreatic cancer. Immunotherapy. 2012 Jan; 4(1):5-7. PMID: 22149993.
    View in: PubMed
  34. Murshid A, Gong J, Stevenson MA, Calderwood SK. Heat shock proteins and cancer vaccines: developments in the past decade and chaperoning in the decade to come. Expert Rev Vaccines. 2011 Nov; 10(11):1553-68. PMID: 22043955.
    View in: PubMed
  35. Koido S, Homma S, Takahara A, Namiki Y, Tsukinaga S, Mitobe J, Odahara S, Yukawa T, Matsudaira H, Nagatsuma K, Uchiyama K, Satoh K, Ito M, Komita H, Arakawa H, Ohkusa T, Gong J, Tajiri H. Current immunotherapeutic approaches in pancreatic cancer. Clin Dev Immunol. 2011; 2011:267539. PMID: 21922022.
    View in: PubMed
  36. Koido S, Homma S, Takahara A, Namiki Y, Komita H, Nagasaki E, Ito M, Nagatsuma K, Uchiyama K, Satoh K, Ohkusa T, Gong J, Tajiri H. Immunologic monitoring of cellular responses by dendritic/tumor cell fusion vaccines. J Biomed Biotechnol. 2011; 2011:910836. PMID: 21541197.
    View in: PubMed
  37. Weng D, Song B, Durfee J, Sugiyama V, Wu Z, Koido S, Calderwood SK, Gong J. Induction of cytotoxic T lymphocytes against ovarian cancer-initiating cells. Int J Cancer. 2011 Oct 15; 129(8):1990-2001. PMID: 21154809.
    View in: PubMed
  38. Murshid A, Theriault J, Gong J, Calderwood SK. Investigating receptors for extracellular heat shock proteins. Methods Mol Biol. 2011; 787:289-302. PMID: 21898244.
    View in: PubMed
  39. Weng D, Calderwood SK, Gong J. Preparation of a heat-shock protein 70-based vaccine from DC-tumor fusion cells. Methods Mol Biol. 2011; 787:255-65. PMID: 21898241.
    View in: PubMed
  40. Koido S, Homma S, Hara E, Namiki Y, Takahara A, Komita H, Nagasaki E, Ito M, Ohkusa T, Gong J, Tajiri H. Regulation of tumor immunity by tumor/dendritic cell fusions. Clin Dev Immunol. 2010; 2010:516768. PMID: 21048993.
    View in: PubMed
  41. Weng D, Cunin MC, Song B, Price BD, Eller MS, Gilchrest BA, Calderwood SK, Gong J. Radiosensitization of mammary carcinoma cells by telomere homolog oligonucleotide pretreatment. Breast Cancer Res. 2010; 12(5):R71. PMID: 20846433.
    View in: PubMed
  42. Murshid A, Gong J, Calderwood SK. Heat shock protein 90 mediates efficient antigen cross presentation through the scavenger receptor expressed by endothelial cells-I. J Immunol. 2010 Sep 1; 185(5):2903-17. PMID: 20686127.
    View in: PubMed
  43. Koido S, Homma S, Hara E, Namiki Y, Ohkusa T, Gong J, Tajiri H. Antigen-specific polyclonal cytotoxic T lymphocytes induced by fusions of dendritic cells and tumor cells. J Biomed Biotechnol. 2010; 2010:752381. PMID: 20379390.
    View in: PubMed
  44. Koido S, Hara E, Homma S, Namiki Y, Komita H, Takahara A, Nagasaki E, Ito M, Sagawa Y, Mitsunaga M, Uchiyama K, Satoh K, Arihiro S, Ohkusa T, Gong J, Tajiri H. Dendritic/pancreatic carcinoma fusions for clinical use: Comparative functional analysis of healthy- versus patient-derived fusions. Clin Immunol. 2010 Jun; 135(3):384-400. PMID: 20226739.
    View in: PubMed
  45. Koido S, Hara E, Homma S, Namiki Y, Ohkusa T, Gong J, Tajiri H. Cancer vaccine by fusions of dendritic and cancer cells. Clin Dev Immunol. 2009; 2009:657369. PMID: 20182533.
    View in: PubMed
  46. Gong J, Zhang Y, Durfee J, Weng D, Liu C, Koido S, Song B, Apostolopoulos V, Calderwood SK. A heat shock protein 70-based vaccine with enhanced immunogenicity for clinical use. J Immunol. 2010 Jan 1; 184(1):488-96. PMID: 19949080.
    View in: PubMed
  47. Jaskelioff M, Song W, Xia J, Liu C, Kramer J, Koido S, Gendler SJ, Calderwood SK, Gong J. Telomerase deficiency and telomere dysfunction inhibit mammary tumors induced by polyomavirus middle T oncogene. Oncogene. 2009 Dec 3; 28(48):4225-36. PMID: 19734944.
    View in: PubMed
  48. Gong J, Zhu B, Murshid A, Adachi H, Song B, Lee A, Liu C, Calderwood SK. T cell activation by heat shock protein 70 vaccine requires TLR signaling and scavenger receptor expressed by endothelial cells-1. J Immunol. 2009 Sep 1; 183(5):3092-8. PMID: 19641135.
    View in: PubMed
  49. Li ZM, Liu WC, Dong S, Luo XL, Li XL, Tao DD, Gong JP, Hu JB. [Overexpression of hSav1 promotes Mst1-induced apoptosis in HeLa cells]. Zhonghua Zhong Liu Za Zhi. 2009 Jul; 31(7):481-4. PMID: 19950692.
    View in: PubMed
  50. Koido S, Hara E, Homma S, Ohkusa T, Gong J, Tajiri H. Cancer immunotherapy by fusions of dendritic cells and tumor cells. Immunotherapy. 2009 Jan; 1(1):49-62. PMID: 20635973.
    View in: PubMed
  51. Wang GH, Luo XL, Sun L, Deng Y, Li XL, Tao DD, Hu JB, Gong JP. [Inhibitory effect of N-terminal 24 amino acids of the p55 gamma, a regulatory subunit of phosphoinositide 3-kinase, on proliferation of colon carcinoma cell line HT29]. Ai Zheng. 2008 Oct; 27(10):1034-8. PMID: 18851781.
    View in: PubMed
  52. Koido S, Homma S, Hara E, Mitsunaga M, Namiki Y, Takahara A, Nagasaki E, Komita H, Sagawa Y, Ohkusa T, Fujise K, Gong J, Tajiri H. In vitro generation of cytotoxic and regulatory T cells by fusions of human dendritic cells and hepatocellular carcinoma cells. J Transl Med. 2008; 6:51. PMID: 18793383.
    View in: PubMed
  53. Apostolopoulos V, Weiner DB, Gong J. Cancer vaccines: methods for inducing immunity. Expert Rev Vaccines. 2008 Sep; 7(7):861-2. PMID: 18767935.
    View in: PubMed
  54. Murshid A, Gong J, Calderwood SK. Heat-shock proteins in cancer vaccines: agents of antigen cross-presentation. Expert Rev Vaccines. 2008 Sep; 7(7):1019-30. PMID: 18767951.
    View in: PubMed
  55. Gong J, Koido S, Calderwood SK. Cell fusion: from hybridoma to dendritic cell-based vaccine. Expert Rev Vaccines. 2008 Sep; 7(7):1055-68. PMID: 18767954.
    View in: PubMed
  56. Ge JN, Huang D, Xiao T, Wang Z, Li XL, Xiao H, Tao DD, Gong JP. [Effect of starvation-induced autophagy on cell cycle of tumor cells]. Ai Zheng. 2008 Aug; 27(8):788-94. PMID: 18710610.
    View in: PubMed
  57. Cao JP, Hu LJ, Li XL, Xiao H, Tao DD, Hu JB, Gong JP. [Preparation of suspension of gastric mucous membrane single cell and expression of cyclins in cells]. Zhonghua Wei Chang Wai Ke Za Zhi. 2008 May; 11(3):253-5. PMID: 18478471.
    View in: PubMed
  58. Lu ZX, Ma XQ, Yang LF, Wang ZL, Zeng L, Li ZJ, Li XN, Tang M, Yi W, Gong JP, Sun LQ, Cao Y. DNAzymes targeted to EBV-encoded latent membrane protein-1 induce apoptosis and enhance radiosensitivity in nasopharyngeal carcinoma. Cancer Lett. 2008 Jul 8; 265(2):226-38. PMID: 18353539.
    View in: PubMed
  59. Calderwood SK, Gong J, Theriault JR, Mambula SS, Gray PJ. Cell stress proteins: novel immunotherapeutics. Novartis Found Symp. 2008; 291:115-31; discussion 131-40. PMID: 18575270.
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  60. Calderwood SK, Theriault J, Gray PJ, Gong J. Cell surface receptors for molecular chaperones. Methods. 2007 Nov; 43(3):199-206. PMID: 17920516.
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  61. Khaleque MA, Bharti A, Gong J, Gray PJ, Sachdev V, Ciocca DR, Stati A, Fanelli M, Calderwood SK. Heat shock factor 1 represses estrogen-dependent transcription through association with MTA1. Oncogene. 2008 Mar 20; 27(13):1886-93. PMID: 17922035.
    View in: PubMed
  62. Koido S, Hara E, Homma S, Mitsunaga M, Takahara A, Nagasaki E, Kawahara H, Watanabe M, Toyama Y, Yanagisawa S, Kobayashi S, Yanaga K, Fujise K, Gong J, Tajiri H. Synergistic induction of antigen-specific CTL by fusions of TLR-stimulated dendritic cells and heat-stressed tumor cells. J Immunol. 2007 Oct 1; 179(7):4874-83. PMID: 17878387.
    View in: PubMed
  63. Koido S, Hara E, Homma S, Fujise K, Gong J, Tajiri H. Dendritic/tumor fusion cell-based vaccination against cancer. Arch Immunol Ther Exp (Warsz). 2007 Sep-Oct; 55(5):281-7. PMID: 18219758.
    View in: PubMed
  64. Xia Y, Wu YQ, Zhang L, Li XL, Yuan HL, He XJ, Tao DD, Gong JP, Qiu FZ. [Effects of mitofusin-2 gene on proliferation and chemosensitivity of human breast carcinoma cell line MCF-7]. Ai Zheng. 2007 Aug; 26(8):815-9. PMID: 17697539.
    View in: PubMed
  65. Koido S, Tanaka Y, Tajiri H, Gong J. Generation and functional assessment of antigen-specific T cells stimulated by fusions of dendritic cells and allogeneic breast cancer cells. Vaccine. 2007 Mar 30; 25(14):2610-9. PMID: 17239504.
    View in: PubMed
  66. Enomoto Y, Bharti A, Khaleque AA, Song B, Liu C, Apostolopoulos V, Xing PX, Calderwood SK, Gong J. Enhanced immunogenicity of heat shock protein 70 peptide complexes from dendritic cell-tumor fusion cells. J Immunol. 2006 Nov 1; 177(9):5946-55. PMID: 17056519.
    View in: PubMed
  67. Fu Q, Cheng J, Han ZB, Li XL, Chen XY, Zhang P, Xiao H, Tao DD, Hu JB, Gong JP. [DNA damage and apoptosis of human airway epithelial cell lines caused by cigarette smoke extract]. Ai Zheng. 2006 Oct; 25(10):1191-7. PMID: 17059759.
    View in: PubMed
  68. Han ZB, Zhang P, Fu Q, Li XL, Ge JN, Tao DD, Hu JB, Gong JP. [Inducement of tumor cell autophagy and cell cycle analysis]. Ai Zheng. 2006 Sep; 25(9):1063-8. PMID: 16965643.
    View in: PubMed
  69. Calderwood SK, Theriault JR, Gong J. How is the immune response affected by hyperthermia and heat shock proteins? Int J Hyperthermia. 2005 Dec; 21(8):713-6. PMID: 16338853.
    View in: PubMed
  70. Koido S, Hara E, Torii A, Homma S, Toyama Y, Kawahara H, Ogawa M, Watanabe M, Yanaga K, Fujise K, Gong J, Toda G. Induction of antigen-specific CD4- and CD8-mediated T-cell responses by fusions of autologous dendritic cells and metastatic colorectal cancer cells. Int J Cancer. 2005 Nov 20; 117(4):587-95. PMID: 15945098.
    View in: PubMed
  71. Koido S, Hara E, Homma S, Torii A, Toyama Y, Kawahara H, Watanabe M, Yanaga K, Fujise K, Tajiri H, Gong J, Toda G. Dendritic cells fused with allogeneic colorectal cancer cell line present multiple colorectal cancer-specific antigens and induce antitumor immunity against autologous tumor cells. Clin Cancer Res. 2005 Nov 1; 11(21):7891-900. PMID: 16278414.
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  72. Khaleque MA, Bharti A, Sawyer D, Gong J, Benjamin IJ, Stevenson MA, Calderwood SK. Induction of heat shock proteins by heregulin beta1 leads to protection from apoptosis and anchorage-independent growth. Oncogene. 2005 Sep 29; 24(43):6564-73. PMID: 16007186.
    View in: PubMed
  73. Calderwood SK, Theriault JR, Gong J. Message in a bottle: role of the 70-kDa heat shock protein family in anti-tumor immunity. Eur J Immunol. 2005 Sep; 35(9):2518-27. PMID: 16144035.
    View in: PubMed
  74. Ding L, Li LL, Yang J, Tao YG, Ye M, Shi Y, Tang M, Yi W, Li XL, Gong JP, Cao Y. Epstein-Barr virus encoded latent membrane protein 1 modulates nuclear translocation of telomerase reverse transcriptase protein by activating nuclear factor-kappaB p65 in human nasopharyngeal carcinoma cells. Int J Biochem Cell Biol. 2005 Sep; 37(9):1881-9. PMID: 15967702.
    View in: PubMed
  75. Xie DX, Wu JH, Feng YD, Li XL, Tao DD, Gong JP. [Analysis of cell cycle checkpoints by cyclins/DNA flow cytometry]. Ai Zheng. 2005 Sep; 24(9):1151-5. PMID: 16159445.
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  76. Koido S, Nikrui N, Ohana M, Xia J, Tanaka Y, Liu C, Durfee JK, Lerner A, Gong J. Assessment of fusion cells from patient-derived ovarian carcinoma cells and dendritic cells as a vaccine for clinical use. Gynecol Oncol. 2005 Nov; 99(2):462-71. PMID: 16137749.
    View in: PubMed
  77. Xie HY, Zuo C, Liu Y, Zhang ZL, Pang DW, Li XL, Gong JP, Dickinson C, Zhou W. Cell-targeting multifunctional nanospheres with both fluorescence and magnetism. Small. 2005 May; 1(5):506-9. PMID: 17193476.
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  78. Tanaka Y, Koido S, Ohana M, Liu C, Gong J. Induction of impaired antitumor immunity by fusion of MHC class II-deficient dendritic cells with tumor cells. J Immunol. 2005 Feb 1; 174(3):1274-80. PMID: 15661883.
    View in: PubMed
  79. Gong J, Koido S, Kato Y, Tanaka Y, Chen D, Jonas A, Galinsky I, DeAngelo D, Avigan D, Kufe D, Stone R. Induction of anti-leukemic cytotoxic T lymphocytes by fusion of patient-derived dendritic cells with autologous myeloblasts. Leuk Res. 2004 Dec; 28(12):1303-12. PMID: 15475072.
    View in: PubMed
  80. Koido S, Ohana M, Liu C, Nikrui N, Durfee J, Lerner A, Gong J. Dendritic cells fused with human cancer cells: morphology, antigen expression, and T cell stimulation. Clin Immunol. 2004 Dec; 113(3):261-9. PMID: 15507391.
    View in: PubMed
  81. Feng YD, Xie DX, Qin JC, Zhong YS, Li XL, Xiao W, Wu JH, Tao DD, Hu JB, Gong JP. [Correlation of intra-cellular localization and variations of active caspase-3 to morphology changes in apoptotic MOLT-4 cells induced by X-ray]. Ai Zheng. 2004 Sep; 23(9):1011-5. PMID: 15363192.
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  82. Avigan D, Vasir B, Gong J, Borges V, Wu Z, Uhl L, Atkins M, Mier J, McDermott D, Smith T, Giallambardo N, Stone C, Schadt K, Dolgoff J, Tetreault JC, Villarroel M, Kufe D. Fusion cell vaccination of patients with metastatic breast and renal cancer induces immunological and clinical responses. Clin Cancer Res. 2004 Jul 15; 10(14):4699-708. PMID: 15269142.
    View in: PubMed
  83. Tanaka Y, Koido S, Xia J, Ohana M, Liu C, Cote GM, Sawyer DB, Calderwood S, Gong J. Development of antigen-specific CD8+ CTL in MHC class I-deficient mice through CD4 to CD8 conversion. J Immunol. 2004 Jun 15; 172(12):7848-58. PMID: 15187169.
    View in: PubMed
  84. Wang Y, Theriault JR, He H, Gong J, Calderwood SK. Expression of a dominant negative heat shock factor-1 construct inhibits aneuploidy in prostate carcinoma cells. J Biol Chem. 2004 Jul 30; 279(31):32651-9. PMID: 15152009.
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  85. Raje N, Hideshima T, Davies FE, Chauhan D, Treon SP, Young G, Tai YT, Avigan D, Gong J, Schlossman RL, Richardson P, Kufe DW, Anderson KC. Tumour cell/dendritic cell fusions as a vaccination strategy for multiple myeloma. Br J Haematol. 2004 May; 125(3):343-52. PMID: 15086415.
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  86. He H, Soncin F, Grammatikakis N, Li Y, Siganou A, Gong J, Brown SA, Kingston RE, Calderwood SK. Elevated expression of heat shock factor (HSF) 2A stimulates HSF1-induced transcription during stress. J Biol Chem. 2003 Sep 12; 278(37):35465-75. PMID: 12813038.
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  87. Chen D, Xia J, Tanaka Y, Chen H, Koido S, Wernet O, Mukherjee P, Gendler SJ, Kufe D, Gong J. Immunotherapy of spontaneous mammary carcinoma with fusions of dendritic cells and mucin 1-positive carcinoma cells. Immunology. 2003 Jun; 109(2):300-7. PMID: 12757626.
    View in: PubMed
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