Nicholas Crossland, DVM, DACVP
Assistant Professor
Boston University Chobanian & Avedisian School of Medicine
Pathology & Laboratory Medicine

DVM, Kansas State University
BS, Kansas State University

Pronouns: he/him/his



Dr. Crossland is a board certified Veterinary Anatomic Pathologist. He shares a dual appointment as an Assistant Professor in the Department of Pathology and Laboratory Medicine at Chobanian and Avedisian School of Medicine and an Investigator at the NEIDL where he directs the NEIDL Comparative Pathology Laboratory (NCPL).

His lab aims to elucidate pathogen-host interactions of highly pathogenic microbes. His lab complements classic pathology approaches with cutting edge technologies such as high throughput tissue staining, spatial transcriptomics and quantitative image analysis. This approach enables the discovery of biological pathways driving and preventing disease. At the translational level, we use our expertise to evaluate the efficacy of medical counter measures with the ultimate goal of alleviating and preventing human suffering.

His lab mentors both MS and PhD students that have their sites on pursuing a career in translational research. He is actively exploring collaborative opportunities with other BUMC faculty members to push the outputs achieved from tissue based assays to drive discovery and enhance our understanding of host-pathogen interactions.

Faculty
Boston University
National Emerging Infectious Disease Lab


Graduate Faculty (Primary Mentor of Grad Students)
Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences




National Emerging Infectious Diseases Laboratories Operations
07/08/2021 - 06/30/2026 (Key Person)
PI: Ronald B. Corley, PhD
NIH/National Institute of Allergy & Infectious Diseases
2UC7AI095321-08

Preclinical Models of Infectious Diseases
07/14/2017 - 07/13/2024 (PI)
NIH/National Institute of Allergy & Infectious Diseases


Vectra Polaris Quantitative Pathology Imaging System
09/20/2021 - 09/19/2022 (PI)
NIH/Office of the Director
1S10OD030269-01

Ventana Discovery Ultra Research Autostainer: an Ex+ Core service
08/01/2019 - 07/31/2020 (PI)
NIH/Office of the Director
1S10OD026983-01



Title


Yr Title Project-Sub Proj Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Rosenbloom R, Gavrish I, Tseng AE, Seidel K, Yabaji SM, Gertje HP, Huber BR, Kramnik I, Crossland NA. Progression and Dissemination of Pulmonary Mycobacterium Avium Infection in a Susceptible Immunocompetent Mouse Model. Int J Mol Sci. 2022 May 26; 23(11).View Related Profiles. PMID: 35682679; PMCID: PMC9181083; DOI: 10.3390/ijms23115999;
     
  2. Carossino M, Nevarez JG, Sakaguchi K, Paulsen DB, Langohr IM, Strother K, Ferracone J, Roy A, Crossland NA, Del Piero F. An outbreak of systemic chlamydiosis in farmed American alligators (Alligator mississippiensis). Vet Pathol. 2022 Sep; 59(5):860-868. PMID: 35502797
     
  3. Kenney DJ, O'Connell AK, Turcinovic J, Montanaro P, Hekman RM, Tamura T, Berneshawi AR, Cafiero TR, Al Abdullatif S, Blum B, Goldstein SI, Heller BL, Gertje HP, Bullitt E, Trachtenberg AJ, Chavez E, Nono ET, Morrison C, Tseng AE, Sheikh A, Kurnick S, Grosz K, Bosmann M, Ericsson M, Huber BR, Saeed M, Balazs AB, Francis KP, Klose A, Paragas N, Campbell JD, Connor JH, Emili A, Crossland NA, Ploss A, Douam F. Humanized mice reveal a macrophage-enriched gene signature defining human lung tissue protection during SARS-CoV-2 infection. Cell Rep. 2022 Apr 19; 39(3):110714.View Related Profiles. PMID: 35421379; PMCID: PMC8977517; DOI: 10.1016/j.celrep.2022.110714;
     
  4. Carossino M, Kenney D, O'Connell AK, Montanaro P, Tseng AE, Gertje HP, Grosz KA, Ericsson M, Huber BR, Kurnick SA, Subramaniam S, Kirkland TA, Walker JR, Francis KP, Klose AD, Paragas N, Bosmann M, Saeed M, Balasuriya UBR, Douam F, Crossland NA. Fatal Neurodissemination and SARS-CoV-2 Tropism in K18-hACE2 Mice Is Only Partially Dependent on hACE2 Expression. Viruses. 2022 03 05; 14(3).View Related Profiles. PMID: 35336942; PMCID: PMC8955233; DOI: 10.3390/v14030535;
     
  5. Miorin L, Mire CE, Ranjbar S, Hume AJ, Huang J, Crossland NA, White KM, Laporte M, Kehrer T, Haridas V, Moreno E, Nambu A, Jangra S, Cupic A, Dejosez M, Abo KA, Tseng AE, Werder RB, Rathnasinghe R, Mutetwa T, Ramos I, de Aja JS, de Alba Rivas CG, Schotsaert M, Corley RB, Falvo JV, Fernandez-Sesma A, Kim C, Rossignol JF, Wilson AA, Zwaka T, Kotton DN, Mühlberger E, García-Sastre A, Goldfeld AE. The oral drug nitazoxanide restricts SARS-CoV-2 infection and attenuates disease pathogenesis in Syrian hamsters. bioRxiv. 2022 Feb 09.View Related Profiles. PMID: 35169796; PMCID: PMC8845418; DOI: 10.1101/2022.02.08.479634;
     
  6. Yin JH, Crossland N, Rinaldi M, Williams SM, Wakamatsu N. Pathology in Practice. J Am Vet Med Assoc. 2021 09 15; 259(6):609-612. PMID: 34448605
     
  7. Chen DY, Khan N, Close BJ, Goel RK, Blum B, Tavares AH, Kenney D, Conway HL, Ewoldt JK, Chitalia VC, Crossland NA, Chen CS, Kotton DN, Baker SC, Fuchs SY, Connor JH, Douam F, Emili A, Saeed M. SARS-CoV-2 Disrupts Proximal Elements in the JAK-STAT Pathway. J Virol. 2021 09 09; 95(19):e0086221.View Related Profiles. PMID: 34260266; PMCID: PMC8428404; DOI: 10.1128/JVI.00862-21;
     
  8. Yen HL, Valkenburg S, Sia SF, Choy KT, Peiris JSM, Wong KHM, Crossland N, Douam F, Nicholls JM. Cellular tropism of SARS-CoV-2 in the respiratory tract of Syrian hamsters and B6.Cg-Tg(K18-ACE2)2Prlmn/J transgenic mice. Vet Pathol. 2022 Jul; 59(4):639-647.View Related Profiles. PMID: 34467820; PMCID: PMC8721337; DOI: 10.1177/03009858211043084;
     
  9. Jaleel Z, Blasberg E, Troiano C, Montanaro P, Mazzilli S, Gertje HP, Crossland NA, Platt M, Spiegel J. Association of vaping with decreased vascular endothelial growth factor expression and decreased microvessel density in cutaneous wound healing tissue in rats. Wound Repair Regen. 2021 11; 29(6):1024-1034.View Related Profiles. PMID: 34129265
     
  10. Barker KA, Etesami NS, Shenoy AT, Arafa EI, Lyon de Ana C, Smith NM, Martin IM, Goltry WN, Barron AM, Browning JL, Kathuria H, Belkina AC, Guillon A, Zhong X, Crossland NA, Jones MR, Quinton LJ, Mizgerd JP. Lung-resident memory B cells protect against bacterial pneumonia. J Clin Invest. 2021 06 01; 131(11).View Related Profiles. PMID: 34060477; PMCID: PMC8159694; DOI: 10.1172/JCI141810;
     
Showing 10 of 28 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 28 publications over 8 distinct years, with a maximum of 8 publications in 2021

YearPublications
20111
20151
20162
20172
20185
20204
20218
20225
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Immunohistochemistry
In Situ Hybridization
Histopathology
Emerging Infectious Diseases
Animal Models, Experimental
Image Analysis, Computer-Assisted
Contact for Mentoring:

620 Albany Street
Boston MA 02118
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