Nicholas Crossland, DVM, DACVP
Assistant Professor
Boston University School of Medicine
Pathology & Laboratory Medicine

DVM, Kansas State University




Dr. Crossland is a board certified Veterinary Anatomic Pathologist. He shares a dual appointment as an Assistant Professor in the Department of Pathology and Laboratory Medicine at Boston University School of Medicine and an Investigator at the NEIDL. His primary responsibility is managing an experimental comparative pathology service that safely and efficiently operates in biosafety levels 3 and 4 (BSL3/4). His specialization is in characterization of translational animal models to elcudidate our understanding of pathogenesis and serve as a platform for evaluating medical counter measures. His lab space is also open to graduate students from the Pathology and Laboratory Medicine Department where he provides mentorship in the development and optimization of multiplex immunohistochemistry and in situ hybridization techniques to answer biological questions with retention of spatial context. He is actively exploring collaborative opportunities with other BUMC faculty members to develop and validate deep learning computational approaches to quantitatively characterize morphomolecular signatures of disease and correlate findings with clinical datasets.

Faculty
Boston University
National Emerging Infectious Disease Lab


Graduate Faculty (Primary Mentor of Grad Students)
Boston University School of Medicine, Graduate Medical Sciences




Vectra Polaris Quantitative Pathology Imaging System
09/20/2021 - 09/19/2022 (PI)
NIH/Office of the Director
1S10OD030269-01

Ventana Discovery Ultra Research Autostainer: an Ex+ Core service
08/01/2019 - 07/31/2020 (PI)
NIH/Office of the Director
1S10OD026983-01



Title


Yr Title Project-Sub Proj Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Carossino M, Nevarez JG, Sakaguchi K, Paulsen DB, Langohr IM, Strother K, Ferracone J, Roy A, Crossland NA, Del Piero F. An outbreak of systemic chlamydiosis in farmed American alligators (Alligator mississippiensis). Vet Pathol. 2022 May 03; 3009858221095269. PMID: 35502797
     
  2. Kenney DJ, O'Connell AK, Turcinovic J, Montanaro P, Hekman RM, Tamura T, Berneshawi AR, Cafiero TR, Al Abdullatif S, Blum B, Goldstein SI, Heller BL, Gertje HP, Bullitt E, Trachtenberg AJ, Chavez E, Nono ET, Morrison C, Tseng AE, Sheikh A, Kurnick S, Grosz K, Bosmann M, Ericsson M, Huber BR, Saeed M, Balazs AB, Francis KP, Klose A, Paragas N, Campbell JD, Connor JH, Emili A, Crossland NA, Ploss A, Douam F. Humanized mice reveal a macrophage-enriched gene signature defining human lung tissue protection during SARS-CoV-2 infection. Cell Rep. 2022 Apr 19; 39(3):110714.View Related Profiles. PMID: 35421379; PMCID: PMC8977517; DOI: 10.1016/j.celrep.2022.110714;
     
  3. Carossino M, Kenney D, O'Connell AK, Montanaro P, Tseng AE, Gertje HP, Grosz KA, Ericsson M, Huber BR, Kurnick SA, Subramaniam S, Kirkland TA, Walker JR, Francis KP, Klose AD, Paragas N, Bosmann M, Saeed M, Balasuriya UBR, Douam F, Crossland NA. Fatal Neurodissemination and SARS-CoV-2 Tropism in K18-hACE2 Mice Is Only Partially Dependent on hACE2 Expression. Viruses. 2022 03 05; 14(3).View Related Profiles. PMID: 35336942; PMCID: PMC8955233; DOI: 10.3390/v14030535;
     
  4. Miorin L, Mire CE, Ranjbar S, Hume AJ, Huang J, Crossland NA, White KM, Laporte M, Kehrer T, Haridas V, Moreno E, Nambu A, Jangra S, Cupic A, Dejosez M, Abo KA, Tseng AE, Werder RB, Rathnasinghe R, Mutetwa T, Ramos I, de Aja JS, de Alba Rivas CG, Schotsaert M, Corley RB, Falvo JV, Fernandez-Sesma A, Kim C, Rossignol JF, Wilson AA, Zwaka T, Kotton DN, Mühlberger E, García-Sastre A, Goldfeld AE. The oral drug nitazoxanide restricts SARS-CoV-2 infection and attenuates disease pathogenesis in Syrian hamsters. bioRxiv. 2022 Feb 09.View Related Profiles. PMID: 35169796; PMCID: PMC8845418; DOI: 10.1101/2022.02.08.479634;
     
  5. Yin JH, Crossland N, Rinaldi M, Williams SM, Wakamatsu N. Pathology in Practice. J Am Vet Med Assoc. 2021 09 15; 259(6):609-612. PMID: 34448605
     
  6. Chen DY, Khan N, Close BJ, Goel RK, Blum B, Tavares AH, Kenney D, Conway HL, Ewoldt JK, Chitalia VC, Crossland NA, Chen CS, Kotton DN, Baker SC, Fuchs SY, Connor JH, Douam F, Emili A, Saeed M. SARS-CoV-2 Disrupts Proximal Elements in the JAK-STAT Pathway. J Virol. 2021 09 09; 95(19):e0086221.View Related Profiles. PMID: 34260266; PMCID: PMC8428404; DOI: 10.1128/JVI.00862-21;
     
  7. Yen HL, Valkenburg S, Sia SF, Choy KT, Peiris JSM, Wong KHM, Crossland N, Douam F, Nicholls JM. Cellular tropism of SARS-CoV-2 in the respiratory tract of Syrian hamsters and B6.Cg-Tg(K18-ACE2)2Prlmn/J transgenic mice. Vet Pathol. 2021 Sep 01; 3009858211043084.View Related Profiles. PMID: 34467820; PMCID: PMC8721337; DOI: 10.1177/03009858211043084;
     
  8. Jaleel Z, Blasberg E, Troiano C, Montanaro P, Mazzilli S, Gertje HP, Crossland NA, Platt M, Spiegel J. Association of vaping with decreased vascular endothelial growth factor expression and decreased microvessel density in cutaneous wound healing tissue in rats. Wound Repair Regen. 2021 11; 29(6):1024-1034.View Related Profiles. PMID: 34129265
     
  9. Barker KA, Etesami NS, Shenoy AT, Arafa EI, Lyon de Ana C, Smith NM, Martin IM, Goltry WN, Barron AM, Browning JL, Kathuria H, Belkina AC, Guillon A, Zhong X, Crossland NA, Jones MR, Quinton LJ, Mizgerd JP. Lung-resident memory B cells protect against bacterial pneumonia. J Clin Invest. 2021 06 01; 131(11).View Related Profiles. PMID: 34060477; PMCID: PMC8159694; DOI: 10.1172/JCI141810;
     
  10. Nambulli S, Xiang Y, Tilston-Lunel NL, Rennick LJ, Sang Z, Klimstra WB, Reed DS, Crossland NA, Shi Y, Duprex WP. Inhalable Nanobody (PiN-21) prevents and treats SARS-CoV-2 infections in Syrian hamsters at ultra-low doses. Sci Adv. 2021 05; 7(22).View Related Profiles. PMID: 34039613; PMCID: PMC8153718; DOI: 10.1126/sciadv.abh0319;
     
Showing 10 of 27 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 27 publications over 8 distinct years, with a maximum of 8 publications in 2021

YearPublications
20111
20151
20162
20172
20185
20204
20218
20224

In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Immunohistochemistry
In Situ Hybridization
Histopathology
Emerging Infectious Diseases
Animal Models, Experimental
Image Analysis, Computer-Assisted
Contact for Mentoring:

620 Albany Street
Boston MA 02118
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