Dr. Crossland is a board certified Veterinary Anatomic Pathologist. He shares a dual appointment as an Assistant Professor in the Department of Pathology and Laboratory Medicine at Boston University School of Medicine and an Investigator at the NEIDL. His primary responsibility is managing an experimental comparative pathology service that safely and efficiently operates in biosafety levels 3 and 4 (BSL3/4). His specialization is in characterization of translational animal models to elcudidate our understanding of pathogenesis and serve as a platform for evaluating medical counter measures. His lab space is also open to graduate students from the Pathology and Laboratory Medicine Department where he provides mentorship in the development and optimization of multiplex immunohistochemistry and in situ hybridization techniques to answer biological questions with retention of spatial context. He is actively exploring collaborative opportunities with other BUMC faculty members to develop and validate deep learning computational approaches to quantitatively characterize morphomolecular signatures of disease and correlate findings with clinical datasets.
National Emerging Infectious Disease Lab
Graduate Faculty (Primary Mentor of Grad Students)
Boston University School of Medicine, Graduate Medical Sciences
Ventana Discovery Ultra Research Autostainer: an Ex+ Core service
08/01/2019 - 07/31/2020 (PI)NIH/Office of the Director1S10OD026983-01
Publications listed below are automatically derived from MEDLINE/PubMed and other
sources, which might result in incorrect or missing publications. Faculty can
to make corrections and additions.
Showing 10 of 21 results.
Chen DY, Khan N, Close BJ, Goel RK, Blum B, Tavares AH, Kenney D, Conway HL, Ewoldt JK, Chitalia VC, Crossland NA, Chen CS, Kotton DN, Baker SC, Fuchs SY, Connor JH, Douam F, Emili A, Saeed M. SARS-CoV-2 disrupts proximal elements in the JAK-STAT pathway. J Virol. 2021 Jul 14; JVI0086221.View Related Profiles. PMID: 34260266
Jaleel Z, Blasberg E, Troiano C, Montanaro P, Mazzilli S, Gertje HP, Crossland NA, Platt M, Spiegel J. Association of vaping with decreased vascular endothelial growth factor expression and decreased microvessel density in cutaneous wound healing tissue in rats. Wound Repair Regen. 2021 Jun 15.View Related Profiles. PMID: 34129265
Barker KA, Etesami NS, Shenoy AT, Arafa EI, Lyon de Ana C, Smith NM, Martin IM, Goltry WN, Barron AM, Browning JL, Kathuria H, Belkina AC, Guillon A, Zhong X, Crossland NA, Jones MR, Quinton LJ, Mizgerd JP. Lung-resident memory B cells protect against bacterial pneumonia. J Clin Invest. 2021 06 01; 131(11).View Related Profiles. PMID: 34060477; PMCID: PMC8159694; DOI: 10.1172/JCI141810;
Nambulli S, Xiang Y, Tilston-Lunel NL, Rennick LJ, Sang Z, Klimstra WB, Reed DS, Crossland NA, Shi Y, Duprex WP. Inhalable Nanobody (PiN-21) prevents and treats SARS-CoV-2 infections in Syrian hamsters at ultra-low doses. Sci Adv. 2021 05; 7(22).View Related Profiles. PMID: 34039613; PMCID: PMC8153718; DOI: 10.1126/sciadv.abh0319;
Nambulli S, Xiang Y, Tilston-Lunel NL, Rennick LJ, Sang Z, Klimstra WB, Reed DS, Crossland NA, Shi Y, Duprex WP. Inhalable Nanobody (PiN-21) prevents and treats SARS-CoV-2 infections in Syrian hamsters at ultra-low doses. bioRxiv. 2021 Feb 23.View Related Profiles. PMID: 33655253; PMCID: PMC7924274; DOI: 10.1101/2021.02.23.432569;
Carossino M, Montanaro P, O'Connell A, Kenney D, Gertje H, Grosz KA, Kurnick SA, Bosmann M, Saeed M, Balasuriya UBR, Douam F, Crossland NA. Fatal neuroinvasion of SARS-CoV-2 in K18-hACE2 mice is partially dependent on hACE2 expression. bioRxiv. 2021 Jan 15.View Related Profiles. PMID: 33469581; PMCID: PMC7814818; DOI: 10.1101/2021.01.13.425144;
Chen DY, Khan N, Close BJ, Goel RK, Blum B, Tavares AH, Kenney D, Conway HL, Ewoldt JK, Kapell S, Chitalia VC, Crossland NA, Chen CS, Kotton DN, Baker SC, Connor JH, Douam F, Emili A, Saeed M. SARS-CoV-2 desensitizes host cells to interferon through inhibition of the JAK-STAT pathway. bioRxiv. 2020 Oct 28.View Related Profiles. PMID: 33140044; PMCID: PMC7605551; DOI: 10.1101/2020.10.27.358259;
Rennick LJ, Nambulli S, Lemon K, Olinger GY, Crossland NA, Millar EL, Duprex WP. Recombinant subtype A and B human respiratory syncytial virus clinical isolates co-infect the respiratory tract of cotton rats. J Gen Virol. 2020 10; 101(10):1056-1068.View Related Profiles. PMID: 32723429
Greenberg A, Huber BR, Liu DX, Logue JP, Hischak AMW, Hart RJ, Abbott M, Isic N, Hisada YM, Mackman N, Bennett RS, Hensley LE, Connor JH, Crossland NA. Quantification of Viral and Host Biomarkers in the Liver of Rhesus Macaques: A Longitudinal Study of Zaire Ebolavirus Strain Kikwit (EBOV/Kik). Am J Pathol. 2020 07; 190(7):1449-1460.View Related Profiles. PMID: 32275904; PMCID: PMC7322367; DOI: 10.1016/j.ajpath.2020.03.003;
Richards S, Walker J, Nakanishi M, Belghasem M, Lyle C, Arinze N, Napoleon MA, Ravid JD, Crossland N, Zhao Q, Rosenberg D, Rahimi N, Chitalia VC. Haploinsufficiency of Casitas B-Lineage Lymphoma Augments the Progression of Colon Cancer in the Background of Adenomatous Polyposis Coli Inactivation. Am J Pathol. 2020 03; 190(3):602-613.View Related Profiles. PMID: 32113662; PMCID: PMC7074366; DOI: 10.1016/j.ajpath.2019.10.024;
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