Wilson S. Colucci, MD
Professor
Boston University School of Medicine
Dept of Medicine
Cardiovascular Medicine

MD, Boston University




Research program studies the basic molecular and cellular mechanisms of myocardial remodeling, and the pathophysiology and treatment of heart failure.

Section Chief of Medicine in Cardiovascular Medicine
Boston University School of Medicine
Medicine
Cardiovascular Medicine

Research Professor
Boston University School of Medicine
Physiology & Biophysics


Member
Boston University
Whitaker Cardiovascular Institute


Member
Boston University
Evans Center for Interdisciplinary Biomedical Research


Graduate Faculty (Primary Mentor of Grad Students)
Boston University School of Medicine, Graduate Medical Sciences




RED-HF
11/01/2008 - 10/31/2013 (PI)
Amgen, Inc.


EMPHASIS-HF
12/15/2008 - 12/15/2011 (PI)
Pfizer, Inc.


ASCEND-HF
01/21/2008 - 12/15/2011 (PI)
Scios Inc


The Balance Study:Treatment of Hyponatremia Based on Lixivaptan in Nyha Class III/IV Cardiac Patient Evaluation
06/01/2008 - 06/30/2010 (PI)
Cardiokine Biopharma


HMG CoA Reductase Inhibition and Inflammation, Oxidative Stress and Vascular Stiffness in Heart Failure
07/01/2005 - 06/30/2006 (Co-PI)
Heart Failure Society of America (HFSA)

Optimize HF Registry
05/01/2003 - 05/01/2005 (PI)
Outcome Sciences (GSK and Duke)

Clinical Evaluation of Acorn Cardiac Support Device Therapy in Patients with Dilated Cardiomyopathy - A Randomized Trial in the United States
02/01/2002 - 01/31/2005 (Co-PI)
Acorn Cardiovascular, Inc.

NO and O2 - In Post-Myocardial Infarction Remodeling and Failure
09/30/1998 - 08/31/2003 (PI)
NIH/National Heart, Lung, and Blood Institute
5 R01 HL61639 05

Double-Blind, Randomized, Placebo-Controlled, Parallel Group Study Evaluating the Effects of Different Doses of LU135252 On Left Ventricle Dimensions, Function, and Left and Right Ventricle Mass, Neurohomone Levels, and Symptoms in Patients with Advanced
07/01/2000 - 06/30/2001 (PI)
Knoll Pharmaceutical Company

Regulation of Vascular Alpha-1 Adrenergic Responses
04/26/1989 - 03/31/2001 (PI)
NIH/National Heart, Lung, and Blood Institute
5 R01 HL42539 10


Effects of cardiac SGLT inhibition on cardiac energetics and hemodynamic function in type II diabete
04/20/2018 - 04/19/2020 (PI)
Merck

Effects of LCZ696 on Myocardial, Hemodynamic Function and Mitochondrial Energetics in Mice with…
04/03/2018 - 03/31/2020 (PI)
Novartis Pharma Corp

Oxidative Stress in Myocardial Remodeling and Failure
04/01/2017 - 03/31/2020 (PI)
NIH-NHLBI
5R01HL064750-12

Effects of ribose supplementation on cardiac remodeling, exercise capacity and mitochondrial functio
05/19/2015 - 08/18/2016 (PI)
Ribocor, Inc.

Modification of Cardiovascular Proteins by Metabolic Disease
08/15/2010 - 08/14/2015 (PI)
Trustees of Boston University NIH-NHLBI

TOPCAT - Amendment #4 Vascular Ancillary Study
02/01/2009 - 06/30/2014 (PI)
New England Res Inst AtCor Medical, Inc.

TOPCAT
09/01/2008 - 06/30/2014 (PI)
New England Res Inst NIH-NHLBI

Oxidative Stress in Myocardial Remodeling and Failure
07/01/2008 - 06/30/2014 (PI)
NIH-NHLBI
5R01 HL064750-08

Role Of Oxidative Stress
05/01/1999 - 12/31/2010 (PI)
GlaxoSmithKline

Mechanisms of Oxidant Signaling in Post-MI
12/01/2003 - 11/30/2010 (PI)
NIH-NHLBI
5 R01 HL 061639-09

Showing 10 of 18 results. Show All Results

Title


Yr Title Project-Sub Proj Pubs
2018 Oxidative Stress in Myocardial Remodeling and Failure 5R01HL064750-12 29
2017 Oxidative Stress in Myocardial Remodeling and Failure 5R01HL064750-11 29
2016 Oxidative Stress in Myocardial Remodeling and Failure 5R01HL064750-10 29
2015 Oxidative Stress in Myocardial Remodeling and Failure 2R01HL064750-09A1 29
2011 Oxidative Stress in Myocardial Remodeling and Failure 5R01HL064750-08 29
2010 Oxidative Stress in Myocardial Remodeling and Failure 5R01HL064750-07 29
2009 Oxidative Stress in Myocardial Remodeling and Failure 5R01HL064750-06 29
2008 Oxidative Stress in Myocardial Remodeling and Failure 2R01HL064750-05A1 29
2007 ACTION - A CHF Trial Investigating Outcomes of Exercise 5U01HL068973-06 26
2007 Mechanisms of Oxidant Signaling in Post-MI Remodeling 5R01HL061639-09 46
Showing 10 of 39 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Panagia M, Yang J, Gale E, Wang H, Luptak I, Chen HH, Patel D, Croteau D, Pimentel DR, Bachschmid MM, Colucci WS, Ran C, Sosnovik DE. A novel tracer for in vivo optical imaging of fatty acid metabolism in the heart and brown adipose tissue. Sci Rep. 2020 Jul 08; 10(1):11209.View Related Profiles. PMID: 32641756
     
  2. Panagia M, He H, Baka T, Pimentel DR, Croteau D, Bachschmid MM, Balschi JA, Colucci WS, Luptak I. Increasing mitochondrial ATP synthesis with butyrate normalizes ADP and contractile function in metabolic heart disease. NMR Biomed. 2020 05; 33(5):e4258.View Related Profiles. PMID: 32066202
     
  3. Tian R, Colucci WS, Arany Z, Bachschmid MM, Ballinger SW, Boudina S, Bruce JE, Busija DW, Dikalov S, Dorn GW, Galis ZS, Gottlieb RA, Kelly DP, Kitsis RN, Kohr MJ, Levy D, Lewandowski ED, McClung JM, Mochly-Rosen D, O'Brien KD, O'Rourke B, Park JY, Ping P, Sack MN, Sheu SS, Shi Y, Shiva S, Wallace DC, Weiss RG, Vernon HJ, Wong R, Schwartz Longacre L. Unlocking the Secrets of Mitochondria in the Cardiovascular System: Path to a Cure in Heart Failure—A Report from the 2018 National Heart, Lung, and Blood Institute Workshop Circulation. 2019 10 01; 140(14):1205-1216.View Related Profiles. PMID: 31769940
     
  4. Luptak I, Morgan R, Baka T, Croteau D, Moverman D, Sarnak H, Kirber M, Bachschmid MM, Colucci WS, Pimentel DR. Genetically targeted fluorescent probes reveal dynamic calcium responses to adrenergic signaling in multiple cardiomyocyte compartments. Int J Biochem Cell Biol. 2019 09; 114:105569.View Related Profiles. PMID: 31299273
     
  5. Luptak I, Croteau D, Valentine C, Qin F, Siwik DA, Remick DG, Colucci WS, Hobai IA. Myocardial Redox Hormesis Protects the Heart of Female Mice in Sepsis. Shock. 2019 07; 52(1):52-60.View Related Profiles. PMID: 30102640
     
  6. Luptak I, Qin F, Sverdlov AL, Pimentel DR, Panagia M, Croteau D, Siwik DA, Bachschmid MM, He H, Balschi JA, Colucci WS. Energetic Dysfunction Is Mediated by Mitochondrial Reactive Oxygen Species and Precedes Structural Remodeling in Metabolic Heart Disease. Antioxid Redox Signal. 2019 09 01; 31(7):539-549.View Related Profiles. PMID: 31088291
     
  7. Gopal DM, Ayalon N, Wang YC, Siwik D, Sverdlov A, Donohue C, Perez A, Downing J, Apovian C, Silva V, Panagia M, Kolachalama V, Ho JE, Liang CS, Gokce N, Colucci WS. Galectin-3 Is Associated With Stage B Metabolic Heart Disease and Pulmonary Hypertension in Young Obese Patients. J Am Heart Assoc. 2019 04 02; 8(7):e011100.View Related Profiles. PMID: 30929550
     
  8. Ngo DTM, Sverdlov AL, Karki S, Macartney-Coxson D, Stubbs RS, Farb MG, Carmine B, Hess DT, Colucci WS, Gokce N. Oxidative modifications of mitochondrial complex II are associated with insulin resistance of visceral fat in obesity. Am J Physiol Endocrinol Metab. 2019 02 01; 316(2):E168-E177.View Related Profiles. PMID: 30576243
     
  9. Panagia M, Chen HH, Croteau D, Iris Chen YC, Ran C, Luptak I, Josephson L, Colucci WS, Sosnovik DE. Multiplexed Optical Imaging of Energy Substrates Reveals That Left Ventricular Hypertrophy Is Associated With Brown Adipose Tissue Activation. Circ Cardiovasc Imaging. 2018 03; 11(3):e007007.View Related Profiles. PMID: 29555834
     
  10. Holubarsch CJF, Colucci WS, Eha J. Benefit-Risk Assessment of Crataegus Extract WS 1442: An Evidence-Based Review. Am J Cardiovasc Drugs. 2018 Feb; 18(1):25-36. PMID: 29080984
     
Showing 10 of 324 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 323 publications over 41 distinct years, with a maximum of 21 publications in 2000 and 2001

YearPublications
19804
19819
19823
19832
19848
19859
198610
19875
19888
198911
19907
19917
19923
19936
19945
199512
199615
199710
199810
19997
200021
200121
200213
20039
200416
200514
20068
20077
20085
20096
20106
20115
20125
20135
20147
20156
20165
20172
20184
20195
20202

In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Heart failure
pathophysiology of heart failure
basic mechanisms of myocardial remodeling
new treatments for heart failure
cardiomyopathy
Contact for Mentoring:

75 E. Newton St Collamore Building
Boston MA 02118
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