Noyan Gokce, MD
Professor
Boston University Chobanian & Avedisian School of Medicine
Medicine
Cardiovascular Medicine

MD, Tufts University School of Medicine
BA, Brandeis University



Dr. Noyan Gokce, MD is Professor of Medicine at Chobanian and Avedisian School of Medicine and Director of Echocardiography at Boston Medical Center. He is a Fellow of the American College of Cardiology (FACC), American Society of Echocardiography (FASE), and a member of the American Society for Clinical Investigation (ASCI). He is board certified in Cardiovascular Diseases and Adult Echocardiography. He is recipient of the “Excellence in Clinical Teaching” award in 2006, 2011, 2017, and 2019 in the Cardiovascular Division. He has been awarded the “Collaborator of the Year” award in Clinical/Translational Sciences at BMC, as well as First Prize in Clinical Research at the Evans Memorial Dept. of Medicine 100th Anniversary Celebration. Dr. Gokce’s translational research focuses on elucidating mechanisms of vascular dysfunction in obesity and metabolic diseases, using both basic and clinical approaches. His laboratory has been NIH funded for 20 consecutive years and he is currently the principal investigator on several NIH R01 grants that study the relationships between dysfunctional adipose tissue in human fat stores and cardiometabolic dysfunction. These studies also seek to characterize pathogenic links between obesity, perivascular adipose remodeling, insulin resistance, inflammation, endothelial dysfunction, and angiogenesis, and investigate how medical and bariatric surgical weight loss interventions regulate adipose tissue metabolism and micro- and macro-vascular phenotypes.

Member
Boston University
Whitaker Cardiovascular Institute


Member
Boston University
Evans Center for Interdisciplinary Biomedical Research


Full Member
Boston University Medical Center
Boston Nutrition Obesity Research Center




Adverse vascular effects of environmental pollutants
07/01/2023 - 06/30/2026 (Multi-PI)
PI: Noyan Gokce, MD
American Heart Association


Impact of Per/Polyfluoroalkyl pollutants on vascular disease mechanisms
07/01/2023 - 06/30/2025 (PI)
NIH/National Institute of Environmental Health Sciences
1R21ES034939-01A1

Wnt signaling control of vascular phenotype in obesity
08/16/2019 - 07/31/2024 (Multi-PI)
PI: Noyan Gokce, MD
NIH/National Heart, Lung, and Blood Institute
5R01HL142650-05

FSP27 regulation of vascular function in human obesity
07/01/2018 - 06/30/2023 (Key Person / Mentor)
PI: Shakun Karki, PhD
NIH/National Diabetes & Digestive & Kidney Diseases
3K01DK114897-04S1

Identifying a novel regulatory pathway of vascular function in obesity
06/01/2018 - 05/31/2023 (PI)
NIH/National Heart, Lung, and Blood Institute
5R01HL140836-04

Determinants of obesity-related insulin resistance
02/01/2017 - 01/31/2023 (Key Person / Mentor)
PI: Melissa G. Farb, PhD
NIH/National Heart, Lung, and Blood Institute
3K23HL135394-05S1

Anti-Angiogenic Mechanisms in Human Obesity
11/14/2014 - 10/31/2020 (Multi-PI)
PI: Noyan Gokce, MD
NIH/National Heart, Lung, and Blood Institute
5R01HL126141-05

Adipose Inflammation, Mitochondrial & Endothelial Phenotypes in Obesity
07/01/2016 - 06/30/2018 (PI)
NIH/National Heart, Lung, and Blood Institute
4R01HL114675-05

Metabolic Control of Endothelial Cell Phenotype
09/30/2005 - 02/28/2017 (PI of Sub-Project / SP)
PI: Kenneth Walsh, PhD
NIH/National Heart, Lung, and Blood Institute
5P01HL081587-10

Adipose Inflammation, Mitochondrial Function & Endothelial Phenotypes in Obesity
07/05/2012 - 06/30/2016 (PI)
NIH/National Heart, Lung, and Blood Institute
5R01HL114675-04

Showing 10 of 12 results. Show All Results

Obesity, Adipocytokines, and Endothelial Dysfunction
08/15/2003 - 07/31/2009 (PI)
NIH-NHLBI
1R01HL074097-05

Endothelial Dysfunction
09/01/2000 - 07/31/2006 (PI)
NIH-NHLBI
5 K23 HL004425-05

Predictive value of Endothelial Disfunction
07/01/2003 - 06/30/2005 (PI)
American Society of Echocardiography

Oxidative Stress And Endotheli
05/30/1998 - 05/29/2001 (PI)
NIH-NHLBI
1 F32 HL09894-03


Title


Yr Title Project-Sub Proj Pubs
2023 Impact of Per/Polyfluoroalkyl pollutants on vascular disease mechanisms 1R21ES034939-01A1
2023 Wnt signaling control of vascular phenotype in obesity 5R01HL142650-05
2022 Wnt signaling control of vascular phenotype in obesity 5R01HL142650-04
2021 Wnt signaling control of vascular phenotype in obesity 5R01HL142650-03
2021 Identifying a novel regulatory pathway of vascular function in obesity 5R01HL140836-04 3
2020 Wnt signaling control of vascular phenotype in obesity 5R01HL142650-02
2020 Identifying a novel regulatory pathway of vascular function in obesity 5R01HL140836-03 3
2019 Wnt signaling control of vascular phenotype in obesity 1R01HL142650-01A1
2019 Identifying a novel regulatory pathway of vascular function in obesity 5R01HL140836-02 3
2019 Anti-Angiogenic Mechanisms in Human Obesity 5R01HL126141-05 30
Showing 10 of 44 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Ahmed B, Farb MG, Karki S, D'Alessandro S, Edwards NM, Gokce N. Pericardial Adipose Tissue Thrombospondin-1 Associates With Antiangiogenesis in Ischemic Heart Disease. Am J Cardiol. 2024 Jan 01; 210:201-207.View Related Profiles. PMID: 37863116; PMCID: PMC10842123; DOI: 10.1016/j.amjcard.2023.09.104;
     
  2. Chavkin NW, Vippa T, Jung C, McDonnell S, Hirschi KK, Gokce N, Walsh K. Obesity accelerates endothelial-to-mesenchymal transition in adipose tissues of mice and humans. Front Cardiovasc Med. 2023; 10:1264479.View Related Profiles. PMID: 37795485; PMCID: PMC10546194; DOI: 10.3389/fcvm.2023.1264479;
     
  3. Balakrishnan B, Gupta A, Basri R, Sharma VM, Slayton M, Gentner K, Becker CC, Karki S, Muturi H, Najjar SM, Loria AS, Gokce N, Puri V. Endothelial-Specific Expression of CIDEC Improves High-Fat Diet-Induced Vascular and Metabolic Dysfunction. Diabetes. 2023 Jan 01; 72(1):19-32.View Related Profiles. PMID: 36256836; PMCID: PMC9797323; DOI: 10.2337/db22-0294;
     
  4. Gupta A, Balakrishnan B, Karki S, Slayton M, Jash S, Banerjee S, Grahn THM, Jambunathan S, Disney S, Hussein H, Kong D, Lowell BB, Natarajan P, Reddy UK, Gokce N, Sharma VM, Puri V. Human CIDEC transgene improves lipid metabolism and protects against high-fat diet-induced glucose intolerance in mice. J Biol Chem. 2022 Sep; 298(9):102347.View Related Profiles. PMID: 35963433; PMCID: PMC9472082; DOI: 10.1016/j.jbc.2022.102347;
     
  5. Gokce N, Karki S, Dobyns A, Zizza E, Sroczynski E, Palmisano JN, Mazzotta C, Hamburg NM, Pernar LI, Carmine B, Carter CO, LaValley M, Hess DT, Apovian CM, Farb MG. Association of Bariatric Surgery With Vascular Outcomes. JAMA Netw Open. 2021 07 01; 4(7):e2115267.View Related Profiles. PMID: 34251443; PMCID: PMC8276087; DOI: 10.1001/jamanetworkopen.2021.15267;
     
  6. Chavkin NW, Sano S, Wang Y, Oshima K, Ogawa H, Horitani K, Sano M, MacLauchlan S, Nelson A, Setia K, Vippa T, Watanabe Y, Saucerman JJ, Hirschi KK, Gokce N, Walsh K. The Cell Surface Receptors Ror1/2 Control Cardiac Myofibroblast Differentiation. J Am Heart Assoc. 2021 07 06; 10(13):e019904.View Related Profiles. PMID: 34155901; PMCID: PMC8403294; DOI: 10.1161/JAHA.120.019904;
     
  7. Mazzotta C, Basu S, Gower AC, Karki S, Farb MG, Sroczynski E, Zizza E, Sarhan A, Pande AN, Walsh K, Dobrilovic N, Gokce N. Perivascular Adipose Tissue Inflammation in Ischemic Heart Disease. Arterioscler Thromb Vasc Biol. 2021 03; 41(3):1239-1250.View Related Profiles. PMID: 33504180; PMCID: PMC7904602; DOI: 10.1161/ATVBAHA.120.315865;
     
  8. Wang Y, Sano S, Oshima K, Sano M, Watanabe Y, Katanasaka Y, Yura Y, Jung C, Anzai A, Swirski FK, Gokce N, Walsh K. Wnt5a-Mediated Neutrophil Recruitment Has an Obligatory Role in Pressure Overload-Induced Cardiac Dysfunction. Circulation. 2019 08 06; 140(6):487-499.View Related Profiles. PMID: 31170826; PMCID: PMC6684855; DOI: 10.1161/CIRCULATIONAHA.118.038820;
     
  9. Karki S, Farb MG, Sharma VM, Jash S, Zizza EJ, Hess DT, Carmine B, Carter CO, Pernar LI, Apovian CM, Puri V, Gokce N. Fat-Specific Protein 27 Regulation of Vascular Function in Human Obesity. J Am Heart Assoc. 2019 06 04; 8(11):e011431.View Related Profiles. PMID: 31433737; PMCID: PMC6585348; DOI: 10.1161/JAHA.118.011431;
     
  10. Gopal DM, Ayalon N, Wang YC, Siwik D, Sverdlov A, Donohue C, Perez A, Downing J, Apovian C, Silva V, Panagia M, Kolachalama V, Ho JE, Liang CS, Gokce N, Colucci WS. Galectin-3 Is Associated With Stage B Metabolic Heart Disease and Pulmonary Hypertension in Young Obese Patients. J Am Heart Assoc. 2019 04 02; 8(7):e011100.View Related Profiles. PMID: 30929550; PMCID: PMC6509711; DOI: 10.1161/JAHA.118.011100;
     
Showing 10 of 93 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 93 publications over 26 distinct years, with a maximum of 8 publications in 2003

YearPublications
19891
19961
19982
19993
20001
20015
20024
20038
20042
20053
20075
20083
20093
20104
20113
20126
20134
20147
20156
20166
20175
20181
20193
20213
20221
20233


Vascular Function: Another Benefit of Bariatric Surgery

Medpage Today 7/12/2021

2019 Cardiovascular Section, Boston Medical Center: Excellence in Clinical Teaching
2017 Cardiovascular Section, Boston Medical Center: Excellence in Clinical Teaching
2013 Leading Physicians of the World: International Association of Cardiologists
2013-2014 Boston Medical Center: First Prize in Clinical Research
2013 NIH Study Section Special Emphasis Panel: Chair
2012 Boston Medical Center: Collaborator of the Year Award
2012 Boston Medical Center: First Prize in Clinical/Translational Research Competition
2011-2011 Department of Cardiology : I received the 2011 Excellence in Clinical Teaching Award from the Section of Cardiology at Boston M
2011 Boston Medical Center: Excellence in Clinical Teaching Award
2010-2010 Department of Evans/Medicine : Work presented from our laboratory by Dr. Melissa Farb received FIRST PRIZE in clinical research in
2010 Boston University Evans Day Intramural Research Competition: First Prize
2006 Boston Medical Center: Excellence in Clinical Teaching Award
2003 America’s Registry of Outstanding Professionals
2000-2005 National Institutes of Health: Research Career Development Award (K-23)
1998-2000 National Institutes of Health: Individual National Research Service Award (NRSA)
1997 New England Research Competition and Award Program: Fellow Finalist
1997-1998 American Heart Association: New England Affiliate Fellowship Award
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Cardiovascular Diseases
Echocardiography
Obesity
Vascular biology
Metabolic Disease
Weight loss
Cardiac Imaging

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