Noyan Gokce, MD
Professor
Boston University School of Medicine
Dept of Medicine
Cardiovascular Medicine

MD, Tufts University School of Medicine




Dr. Noyan Gokce, MD is Professor of Medicine at Boston University School of Medicine and Director of Echocardiography at Boston Medical Center. He is a Fellow of the American College of Cardiology (FACC), American Society of Echocardiography (FASE), and a member of the American Society for Clinical Investigation (ASCI). He is board certified in Cardiovascular Diseases and Adult Echocardiography. He is recipient of the “Excellence in Clinical Teaching” award in 2006, 2011, 2017, and 2019 in the Cardiovascular Division. He has been awarded the “Collaborator of the Year” award in Clinical/Translational Sciences at BMC, as well as First Prize in Clinical Research at the Evans Memorial Dept. of Medicine 100th Anniversary Celebration. Dr. Gokce’s translational research focuses on elucidating mechanisms of vascular dysfunction in obesity and metabolic diseases, using both basic and clinical approaches. His laboratory has been NIH funded for 20 consecutive years and he is currently the principal investigator on several NIH R01 grants that study the relationships between dysfunctional adipose tissue in human fat stores and cardiometabolic dysfunction. These studies also seek to characterize pathogenic links between obesity, perivascular adipose remodeling, insulin resistance, inflammation, endothelial dysfunction, and angiogenesis, and investigate how medical and bariatric surgical weight loss interventions regulate adipose tissue metabolism and micro- and macro-vascular phenotypes.

Member
Boston University
Whitaker Cardiovascular Institute


Member
Boston University
Evans Center for Interdisciplinary Biomedical Research


Full Member
Boston University Medical Center
Boston Nutrition Obesity Research Center



2019 Cardiovascular Section, Boston Medical Center: Excellence in Clinical Teaching
2017 Cardiovascular Section, Boston Medical Center: Excellence in Clinical Teaching
2013 Leading Physicians of the World: International Association of Cardiologists
2013-2014 Boston Medical Center: First Prize in Clinical Research
2013 NIH Study Section Special Emphasis Panel: Chair
2012 Boston Medical Center: Collaborator of the Year Award
2012 Boston Medical Center: First Prize in Clinical/Translational Research Competition
2011-2011 Department of Cardiology : I received the 2011 Excellence in Clinical Teaching Award from the Section of Cardiology at Boston M
2011 Boston Medical Center: Excellence in Clinical Teaching Award
2010-2010 Department of Evans/Medicine : Work presented from our laboratory by Dr. Melissa Farb received FIRST PRIZE in clinical research in
2010 Boston University Evans Day Intramural Research Competition: First Prize
2006 Boston Medical Center: Excellence in Clinical Teaching Award
2003 America’s Registry of Outstanding Professionals
2000-2005 National Institutes of Health: Research Career Development Award (K-23)
1998-2000 National Institutes of Health: Individual National Research Service Award (NRSA)
1997 New England Research Competition and Award Program: Fellow Finalist
1997-1998 American Heart Association: New England Affiliate Fellowship Award


Wnt signaling control of vascular phenotype in obesity
08/16/2019 - 07/31/2024 (Multi-PI)
PI: Noyan Gokce, MD
NIH/National Heart, Lung, and Blood Institute
1R01HL142650-01A1

Identifying a novel regulatory pathway of vascular function in obesity
06/01/2018 - 05/31/2022 (PI)
NIH/National Heart, Lung, and Blood Institute
5R01HL140836-02

Anti-Angiogenic Mechanisms in Human Obesity
11/14/2014 - 10/31/2020 (Multi-PI)
PI: Noyan Gokce, MD
NIH/National Heart, Lung, and Blood Institute
5R01HL126141-05

Adipose Inflammation, Mitochondrial & Endothelial Phenotypes in Obesity
07/01/2016 - 06/30/2018 (PI)
NIH/National Heart, Lung, and Blood Institute
4R01HL114675-05

Metabolic Control of Endothelial Cell Phenotype
09/30/2005 - 02/28/2017 (PI of Sub-Project / SP)
PI: Kenneth Walsh, PhD
NIH/National Heart, Lung, and Blood Institute
5P01HL081587-10

Adipose Inflammation, Mitochondrial Function & Endothelial Phenotypes in Obesity
07/05/2012 - 06/30/2016 (PI)
NIH/National Heart, Lung, and Blood Institute
5R01HL114675-04

Contribution of Myeloperoxidasae Activity to Endothelial Dysfunction in Adipose Tissue Arterioles Isolated from Obese Human Subjects
07/01/2012 - 06/30/2015 (PI)
Pfizer, Inc.


Inflammation and Vascular Dysfunction in Obesity
02/20/2007 - 01/31/2013 (PI)
NIH/National Heart, Lung, and Blood Institute
5R01HL084213-05


Obesity, Adipocytokines, and Endothelial Dysfunction
08/15/2003 - 07/31/2009 (PI)
NIH-NHLBI
1R01HL074097-05

Endothelial Dysfunction
09/01/2000 - 07/31/2006 (PI)
NIH-NHLBI
5 K23 HL004425-05

Predictive value of Endothelial Disfunction
07/01/2003 - 06/30/2005 (PI)
American Society of Echocardiography

Oxidative Stress And Endotheli
05/30/1998 - 05/29/2001 (PI)
NIH-NHLBI
1 F32 HL09894-03


Title


Yr Title Project-Sub Proj Pubs
2020 Wnt signaling control of vascular phenotype in obesity 5R01HL142650-02
2020 Identifying a novel regulatory pathway of vascular function in obesity 5R01HL140836-03 3
2019 Wnt signaling control of vascular phenotype in obesity 1R01HL142650-01A1
2019 Identifying a novel regulatory pathway of vascular function in obesity 5R01HL140836-02 3
2019 Anti-Angiogenic Mechanisms in Human Obesity 5R01HL126141-05 30
2019 Anti-Angiogenic Mechanisms in Human Obesity 5R01HL126141-05 30
2018 Identifying a novel regulatory pathway of vascular function in obesity 1R01HL140836-01A1 3
2018 Anti-Angiogenic Mechanisms in Human Obesity 5R01HL126141-04 30
2017 Anti-Angiogenic Mechanisms in Human Obesity 5R01HL126141-03 30
2016 Anti-Angiogenic Mechanisms in Human Obesity 5R01HL126141-02 30
Showing 10 of 40 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Wang Y, Sano S, Oshima K, Sano M, Watanabe Y, Katanasaka Y, Yura Y, Jung C, Anzai A, Swirski FK, Gokce N, Walsh K. Wnt5a-Mediated Neutrophil Recruitment Has an Obligatory Role in Pressure Overload-Induced Cardiac Dysfunction. Circulation. 2019 08 06; 140(6):487-499.View Related Profiles. PMID: 31170826
     
  2. Karki S, Farb MG, Sharma VM, Jash S, Zizza EJ, Hess DT, Carmine B, Carter CO, Pernar LI, Apovian CM, Puri V, Gokce N. Fat-Specific Protein 27 Regulation of Vascular Function in Human Obesity. J Am Heart Assoc. 2019 06 04; 8(11):e011431.View Related Profiles. PMID: 31433737
     
  3. Gopal DM, Ayalon N, Wang YC, Siwik D, Sverdlov A, Donohue C, Perez A, Downing J, Apovian C, Silva V, Panagia M, Kolachalama V, Ho JE, Liang CS, Gokce N, Colucci WS. Galectin-3 Is Associated With Stage B Metabolic Heart Disease and Pulmonary Hypertension in Young Obese Patients. J Am Heart Assoc. 2019 04 02; 8(7):e011100.View Related Profiles. PMID: 30929550
     
  4. Ngo DTM, Sverdlov AL, Karki S, Macartney-Coxson D, Stubbs RS, Farb MG, Carmine B, Hess DT, Colucci WS, Gokce N. Oxidative modifications of mitochondrial complex II are associated with insulin resistance of visceral fat in obesity. Am J Physiol Endocrinol Metab. 2019 02 01; 316(2):E168-E177.View Related Profiles. PMID: 30576243
     
  5. Zuriaga MA, Fuster JJ, Farb MG, MacLauchlan S, Bretón-Romero R, Karki S, Hess DT, Apovian CM, Hamburg NM, Gokce N, Walsh K. Activation of non-canonical WNT signaling in human visceral adipose tissue contributes to local and systemic inflammation. Sci Rep. 2017 12 11; 7(1):17326.View Related Profiles. PMID: 29229927; DOI: 10.1038/s41598-017-17509-5;
     
  6. Farb MG, Park SY, Karki S, Gokce N. Assessment of Human Adipose Tissue Microvascular Function Using Videomicroscopy. J Vis Exp. 2017 Sep 29; (127).View Related Profiles. PMID: 28994775
     
  7. Zuriaga MA, Fuster JJ, Maclauchlan S, Gokce N, Walsh K. Coordinated activation of WNT/planar cell polarity signaling in inflamed visceral fat of obese individuals. Atherosclerosis. 2017 Aug; 263:e8.View Related Profiles. PMID: 29366230
     
  8. Zuriaga MA, Fuster JJ, Gokce N, Walsh K. Humans and Mice Display Opposing Patterns of "Browning" Gene Expression in Visceral and Subcutaneous White Adipose Tissue Depots. Front Cardiovasc Med. 2017; 4:27.View Related Profiles. PMID: 28529941
     
  9. Karki S, Ngo DTM, Farb MG, Park SY, Saggese SM, Hamburg NM, Carmine B, Hess DT, Walsh K, Gokce N. WNT5A regulates adipose tissue angiogenesis via antiangiogenic VEGF-A165b in obese humans. Am J Physiol Heart Circ Physiol. 2017 Jul 01; 313(1):H200-H206.View Related Profiles. PMID: 28411232; DOI: 10.1152/ajpheart.00776.2016;
     
  10. Farb MG, Karki S, Park SY, Saggese SM, Carmine B, Hess DT, Apovian C, Fetterman JL, Bretón-Romero R, Hamburg NM, Fuster JJ, Zuriaga MA, Walsh K, Gokce N. WNT5A-JNK regulation of vascular insulin resistance in human obesity. Vasc Med. 2016 Dec; 21(6):489-496.View Related Profiles. PMID: 27688298
     
Showing 10 of 86 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 86 publications over 23 distinct years, with a maximum of 8 publications in 2003

YearPublications
19891
19961
19982
19993
20001
20015
20024
20038
20042
20053
20075
20083
20093
20104
20113
20126
20134
20147
20156
20166
20175
20181
20193

In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Cardiovascular Diseases
Echocardiography
Obesity
Vascular biology
Metabolic Disease
Weight loss
Cardiac Imaging

Available to Mentor as: (Review Mentor Role Definitions):
  • Research / Scholarly Mentor
Contact for Mentoring:

75 E. Newton St Collamore Building
Boston MA 02118
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