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PhD, University of California, Berkeley
BS, Bowling Green State University

Websites

	Program in Inflammatory Disorders Faculty
	Whitaker Cardiovascular Institute Training Program

ORCID : 0000-0001-7580-2276

Research
Publications

BU Research
NIH RePORTER Research

Wnt signaling control of vascular phenotype in obesity
08/16/2019 - 07/31/2024 (Multi-PI)
PI: Kenneth Walsh, PhD
NIH/National Heart, Lung, and Blood Institute
5R01HL142650-05

Anti-Angiogenic Mechanisms in Human Obesity
11/14/2014 - 10/31/2020 (Multi-PI)
PI: Kenneth Walsh, PhD
NIH/National Heart, Lung, and Blood Institute
5R01HL126141-05

Myokine Control of Hepatic Steatosis
09/15/2016 - 05/31/2018 (PI)
NIH/National Institute on Aging
5R21AG052160-02

Inflammatory Pathways in Aortic Aneurysms
04/01/2016 - 04/12/2018 (PI)
NIH/National Heart, Lung, and Blood Institute
5R01HL132564-03

Somatic TET2 mutations in cardiac remodeling
07/15/2017 - 03/31/2018 (PI)
NIH/National Heart, Lung, and Blood Institute
1R01HL138014-01

Follistatin-like protein 1 in cardiac and systemic metabolism
04/01/2016 - 03/31/2018 (Subcontract PI)
Temple University of the Commonwealth System of Higher Education NIH NHLBI
5R01HL129120-02

Inflammatory Wnt signaling in ischemic myocardium
01/01/2016 - 03/31/2018 (PI)
NIH/National Heart, Lung, and Blood Institute
5R01HL131006-03

Role of WNT/PCP signaling in adipose tissue fibrosis
01/01/2017 - 01/31/2018 (Key Person / Mentor)
PI: Maria Zuriaga Herrero, PhD
American Heart Association

Cardio-metabolic actions of FSTL1
03/28/2013 - 09/30/2017 (PI)
Takeda Pharmaceuticals North America, Inc.

Paracrine Regulation of Heart Failure
07/01/2016 - 06/30/2017 (PI)
NIH/National Heart, Lung, and Blood Institute
4R01HL116591-04

Showing 10 of 34 results. Show All Results

Title

Yr	Title	Project-Sub Proj
2023	Mosaic loss of Y chromosome in blood and heart failure	3R01AG073249-02S1
2023	Mosaic loss of Y chromosome in blood and heart failure	5R01AG073249-03
2023	Role of therapy-related clonal hematopoiesis in anthracycline-induced cardiotoxicity	5R01HL152174-04
2023	Wnt signaling control of vascular phenotype in obesity	5R01HL142650-05
2022	Mosaic loss of Y chromosome in blood and heart failure	5R01AG073249-02
2022	Clonal hematopoiesis and severity of COVID-19 disease	5R21AG072095-02
2022	Role of therapy-related clonal hematopoiesis in anthracycline-induced cardiotoxicity	5R01HL152174-03
2022	Wnt signaling control of vascular phenotype in obesity	5R01HL142650-04
2022	Hematopoietic stem cell mutations and ischemic cardio-metabolic disease	5R01HL141256-04
2022	Clonal hematopoiesis and accelerated metabolic dysfunction in obesity	5R01HL139819-04

Showing 10 of 168 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis Copy PMIDs To Clipboard

Park E, Evans MA, Doviak H, Horitani K, Ogawa H, Yura Y, Wang Y, Sano S, Walsh K. Bone Marrow Transplantation Procedures in Mice to Study Clonal Hematopoiesis. J Vis Exp. 2021 05 26; (171). PMID: 34125083

Chavkin NW, Min KD, Walsh K. Importance of clonal hematopoiesis in heart failure. Trends Cardiovasc Med. 2022 May; 32(4):198-203.View Related Profiles.

Walsh, Kenneth
Chavkin, Nicholas

PMID: 33892102; PMCID: PMC8526615; DOI: 10.1016/j.tcm.2021.04.005;

Mazzotta C, Basu S, Gower AC, Karki S, Farb MG, Sroczynski E, Zizza E, Sarhan A, Pande AN, Walsh K, Dobrilovic N, Gokce N. Perivascular Adipose Tissue Inflammation in Ischemic Heart Disease. Arterioscler Thromb Vasc Biol. 2021 03; 41(3):1239-1250.View Related Profiles.

Gower, Adam
Pande, Ashvin
Mazzotta, Celestina
Walsh, Kenneth
Farb, Melissa
Dobrilovic, Nikola
Gokce, Noyan
Karki, Shakun

PMID: 33504180; PMCID: PMC7904602; DOI: 10.1161/ATVBAHA.120.315865;

Evans MA, Walsh K. A Single-Cell Analysis of DNMT3A-Mediated Clonal Hematopoiesis in Heart Failure. Circ Res. 2021 01 22; 128(2):229-231. PMID: 33476205; PMCID: PMC7839253; DOI: 10.1161/CIRCRESAHA.120.318575;

Evans MA, Sano S, Walsh K. Clonal haematopoiesis and cardiovascular disease: how low can you go? Eur Heart J. 2021 01 20; 42(3):266-268. PMID: 33313787

Fuster JJ, Zuriaga MA, Zorita V, MacLauchlan S, Polackal MN, Viana-Huete V, Ferrer-Pérez A, Matesanz N, Herrero-Cervera A, Sano S, Cooper MA, González-Navarro H, Walsh K. TET2-Loss-of-Function-Driven Clonal Hematopoiesis Exacerbates Experimental Insulin Resistance in Aging and Obesity. Cell Rep. 2020 10 27; 33(4):108326.View Related Profiles.

Walsh, Kenneth
Maclauchlan, Susan

PMID: 33113366; PMCID: PMC7856871; DOI: 10.1016/j.celrep.2020.108326;

Chavkin NW, Walsh K, Hirschi KK. Isolation of Highly Purified and Viable Retinal Endothelial Cells. J Vasc Res. 2021; 58(1):49-57.View Related Profiles.

Walsh, Kenneth
Chavkin, Nicholas

PMID: 33022674; PMCID: PMC7850292; DOI: 10.1159/000510533;

Sano S, Wang Y, Walsh K. Somatic mosaicism: implications for the cardiovascular system. Eur Heart J. 2020 08 07; 41(30):2904-2907. PMID: 31876923; PMCID: PMC7421771; DOI: 10.1093/eurheartj/ehz907;

Shah SA, Cui SX, Waters CD, Sano S, Wang Y, Doviak H, Leor J, Walsh K, French BA, Epstein FH. Nitroxide-enhanced MRI of cardiovascular oxidative stress. NMR Biomed. 2020 09; 33(9):e4359. PMID: 32648316; PMCID: PMC7904044; DOI: 10.1002/nbm.4359;

Jung C, Evans MA, Walsh K. Genetics of age-related clonal hematopoiesis and atherosclerotic cardiovascular disease. Curr Opin Cardiol. 2020 05; 35(3):219-225. PMID: 32073406; PMCID: PMC7138732; DOI: 10.1097/HCO.0000000000000726;

Showing 10 of 134 results. Show More

Wang Y, Sano S, Yura Y, Ke Z, Sano M, Oshima K, Ogawa H, Horitani K, Min KD, Miura-Yura E, Kour A, Evans MA, Zuriaga MA, Hirschi KK, Fuster JJ, Pietras EM, Walsh K. Tet2-mediated clonal hematopoiesis in nonconditioned mice accelerates age-associated cardiac dysfunction. JCI Insight. 2020 03 26; 5(6). PMID: 32154790; PMCID: PMC7213793; DOI: 10.1172/jci.insight.135204;

Yura Y, Sano S, Walsh K. Clonal Hematopoiesis: A New Step Linking Inflammation to Heart Failure. JACC Basic Transl Sci. 2020 Feb; 5(2):196-207. PMID: 32140625; PMCID: PMC7046537; DOI: 10.1016/j.jacbts.2019.08.006;

Evans MA, Sano S, Walsh K. Cardiovascular Disease, Aging, and Clonal Hematopoiesis. Annu Rev Pathol. 2020 01 24; 15:419-438. PMID: 31689371; PMCID: PMC7104598; DOI: 10.1146/annurev-pathmechdis-012419-032544;

Sano S, Wang Y, Evans MA, Yura Y, Sano M, Ogawa H, Horitani K, Doviak H, Walsh K. Lentiviral CRISPR/Cas9-Mediated Genome Editing for the Study of Hematopoietic Cells in Disease Models. J Vis Exp. 2019 10 03; (152). PMID: 31633690; PMCID: PMC7249700; DOI: 10.3791/59977;

Sano S, Wang Y, Yura Y, Sano M, Oshima K, Yang Y, Katanasaka Y, Min KD, Matsuura S, Ravid K, Mohi G, Walsh K. JAK2V617F -Mediated Clonal Hematopoiesis Accelerates Pathological Remodeling in Murine Heart Failure. JACC Basic Transl Sci. 2019 Oct; 4(6):684-697.View Related Profiles.

Ravid, Katya
Walsh, Kenneth
Matsuura, Shinobu

PMID: 31709318; PMCID: PMC6834960; DOI: 10.1016/j.jacbts.2019.05.013;

Wang Y, Sano S, Oshima K, Sano M, Watanabe Y, Katanasaka Y, Yura Y, Jung C, Anzai A, Swirski FK, Gokce N, Walsh K. Wnt5a-Mediated Neutrophil Recruitment Has an Obligatory Role in Pressure Overload-Induced Cardiac Dysfunction. Circulation. 2019 08 06; 140(6):487-499.View Related Profiles.

Walsh, Kenneth
Gokce, Noyan

PMID: 31170826; PMCID: PMC6684855; DOI: 10.1161/CIRCULATIONAHA.118.038820;

Kivelä R, Hemanthakumar KA, Vaparanta K, Robciuc M, Izumiya Y, Kidoya H, Takakura N, Peng X, Sawyer DB, Elenius K, Walsh K, Alitalo K. Endothelial Cells Regulate Physiological Cardiomyocyte Growth via VEGFR2-Mediated Paracrine Signaling. Circulation. 2019 05 28; 139(22):2570-2584. PMID: 30922063; PMCID: PMC6553980; DOI: 10.1161/CIRCULATIONAHA.118.036099;

Anzai A, Mindur JE, Halle L, Sano S, Choi JL, He S, McAlpine CS, Chan CT, Kahles F, Valet C, Fenn AM, Nairz M, Rattik S, Iwamoto Y, Fairweather D, Walsh K, Libby P, Nahrendorf M, Swirski FK. Self-reactive CD4+ IL-3+ T cells amplify autoimmune inflammation in myocarditis by inciting monocyte chemotaxis. J Exp Med. 2019 02 04; 216(2):369-383. PMID: 30670465; PMCID: PMC6363430; DOI: 10.1084/jem.20180722;

Sano S, Wang Y, Walsh K. Clonal Hematopoiesis and Its Impact on Cardiovascular Disease. Circ J. 2018 12 25; 83(1):2-11. PMID: 30185689; PMCID: PMC6310086; DOI: 10.1253/circj.CJ-18-0871;

Maruyama S, Wu CL, Yoshida S, Zhang D, Li PH, Wu F, Parker Duffen J, Yao R, Jardin B, Adham IM, Law R, Berger J, Di Marchi R, Walsh K. Relaxin Family Member Insulin-Like Peptide 6 Ameliorates Cardiac Fibrosis and Prevents Cardiac Remodeling in Murine Heart Failure Models. J Am Heart Assoc. 2018 06 10; 7(12).View Related Profiles.

Wu, Chia-Ling
Walsh, Kenneth
Maruyama, Sonomi

PMID: 29887522; PMCID: PMC6220528; DOI: 10.1161/JAHA.117.008441;

Sano S, Oshima K, Wang Y, Katanasaka Y, Sano M, Walsh K. CRISPR-Mediated Gene Editing to Assess the Roles of Tet2 and Dnmt3a in Clonal Hematopoiesis and Cardiovascular Disease. Circ Res. 2018 07 20; 123(3):335-341. PMID: 29728415; PMCID: PMC6054544; DOI: 10.1161/CIRCRESAHA.118.313225;

Sano S, Oshima K, Wang Y, MacLauchlan S, Katanasaka Y, Sano M, Zuriaga MA, Yoshiyama M, Goukassian D, Cooper MA, Fuster JJ, Walsh K. Tet2-Mediated Clonal Hematopoiesis Accelerates Heart Failure Through a Mechanism Involving the IL-1ß/NLRP3 Inflammasome. J Am Coll Cardiol. 2018 02 27; 71(8):875-886.View Related Profiles.

Goukassian, David
Walsh, Kenneth
Zuriaga Herrero, Maria
Maclauchlan, Susan

PMID: 29471939; PMCID: PMC5828038; DOI: 10.1016/j.jacc.2017.12.037;

Fuster JJ, Walsh K. Somatic Mutations and Clonal Hematopoiesis: Unexpected Potential New Drivers of Age-Related Cardiovascular Disease. Circ Res. 2018 02 02; 122(3):523-532.View Related Profiles.

Fuster Ortuno, Jose
Walsh, Kenneth

PMID: 29420212; PMCID: PMC5826570; DOI: 10.1161/CIRCRESAHA.117.312115;

Seki M, Powers JC, Maruyama S, Zuriaga MA, Wu CL, Kurishima C, Kim L, Johnson J, Poidomani A, Wang T, Muñoz E, Rajan S, Park JY, Walsh K, Recchia FA. Acute and Chronic Increases of Circulating FSTL1 Normalize Energy Substrate Metabolism in Pacing-Induced Heart Failure. Circ Heart Fail. 2018 01; 11(1):e004486.View Related Profiles.

Wu, Chia-Ling
Park, Joongheum
Walsh, Kenneth
Zuriaga Herrero, Maria
Maruyama, Sonomi

PMID: 29317401; PMCID: PMC5765881; DOI: 10.1161/CIRCHEARTFAILURE.117.004486;

Zuriaga MA, Fuster JJ, Farb MG, MacLauchlan S, Bretón-Romero R, Karki S, Hess DT, Apovian CM, Hamburg NM, Gokce N, Walsh K. Activation of non-canonical WNT signaling in human visceral adipose tissue contributes to local and systemic inflammation. Sci Rep. 2017 12 11; 7(1):17326.View Related Profiles.

Apovian, Caroline
Hess, Donald
Walsh, Kenneth
Zuriaga Herrero, Maria
Farb, Melissa
Hamburg, Naomi
Gokce, Noyan
Karki, Shakun
Maclauchlan, Susan

PMID: 29229927; PMCID: PMC5725530; DOI: 10.1038/s41598-017-17509-5;

Neppl RL, Wu CL, Walsh K. lncRNA Chronos is an aging-induced inhibitor of muscle hypertrophy. J Cell Biol. 2017 Nov 06; 216(11):3497-3507.View Related Profiles.

Wu, Chia-Ling
Walsh, Kenneth

PMID: 28855249; PMCID: PMC5674882; DOI: 10.1083/jcb.201612100;

Zuriaga MA, Fuster JJ, Maclauchlan S, Gokce N, Walsh K. Coordinated activation of WNT/planar cell polarity signaling in inflamed visceral fat of obese individuals. Atherosclerosis. 2017 Aug; 263:e8.View Related Profiles.

Walsh, Kenneth
Gokce, Noyan
Maclauchlan, Susan

PMID: 29366230

Fuster JJ, Maclauchlan S, Zuriaga MA, Polackal MN, Walsh K. Clonal hematopoiesis associated with TET2 deficiency accelerates atherosclerosis in hyperlipidemic mice. Atherosclerosis. 2017 Aug; 263:e14.View Related Profiles.

Walsh, Kenneth
Maclauchlan, Susan

PMID: 29365557

MacLauchlan S, Zuriaga MA, Fuster JJ, Cuda CM, Jonason J, Behzadi F, Duffen JP, Haines GK, Aprahamian T, Perlman H, Walsh K. Genetic deficiency of Wnt5a diminishes disease severity in a murine model of rheumatoid arthritis. Arthritis Res Ther. 2017 Jul 19; 19(1):166.View Related Profiles.

Fuster Ortuno, Jose
Walsh, Kenneth
Zuriaga Herrero, Maria
Maclauchlan, Susan
Aprahamian, Tamar

PMID: 28724439; PMCID: PMC5518154; DOI: 10.1186/s13075-017-1375-0;

Sasi SP, Yan X, Zuriaga-Herrero M, Gee H, Lee J, Mehrzad R, Song J, Onufrak J, Morgan J, Enderling H, Walsh K, Kishore R, Goukassian DA. Different Sequences of Fractionated Low-Dose Proton and Single Iron-Radiation-Induced Divergent Biological Responses in the Heart. Radiat Res. 2017 Aug; 188(2):191-203.View Related Profiles.

Goukassian, David
Walsh, Kenneth

PMID: 28613990; PMCID: PMC6555403; DOI: 10.1667/RR14667.1;

Zuriaga MA, Fuster JJ, Gokce N, Walsh K. Humans and Mice Display Opposing Patterns of "Browning" Gene Expression in Visceral and Subcutaneous White Adipose Tissue Depots. Front Cardiovasc Med. 2017; 4:27.View Related Profiles.

Fuster Ortuno, Jose
Walsh, Kenneth
Zuriaga Herrero, Maria
Gokce, Noyan

PMID: 28529941; PMCID: PMC5418233; DOI: 10.3389/fcvm.2017.00027;

Karki S, Ngo DTM, Farb MG, Park SY, Saggese SM, Hamburg NM, Carmine B, Hess DT, Walsh K, Gokce N. WNT5A regulates adipose tissue angiogenesis via antiangiogenic VEGF-A165b in obese humans. Am J Physiol Heart Circ Physiol. 2017 Jul 01; 313(1):H200-H206.View Related Profiles.

Carmine, Brian
Ngo, Doan
Hess, Donald
Walsh, Kenneth
Farb, Melissa
Hamburg, Naomi
Gokce, Noyan
Karki, Shakun

PMID: 28411232; PMCID: PMC6148084; DOI: 10.1152/ajpheart.00776.2016;

Hirschi KK, Nicoli S, Walsh K. Hematopoiesis Lineage Tree Uprooted: Every Cell Is a Rainbow. Dev Cell. 2017 04 10; 41(1):7-9. PMID: 28399402; PMCID: PMC6183053; DOI: 10.1016/j.devcel.2017.03.020;

Wu CL, Satomi Y, Walsh K. RNA-seq and metabolomic analyses of Akt1-mediated muscle growth reveals regulation of regenerative pathways and changes in the muscle secretome. BMC Genomics. 2017 Feb 16; 18(1):181.View Related Profiles.

Wu, Chia-Ling
Walsh, Kenneth

PMID: 28209124; PMCID: PMC5314613; DOI: 10.1186/s12864-017-3548-2;

Fuster JJ, MacLauchlan S, Zuriaga MA, Polackal MN, Ostriker AC, Chakraborty R, Wu CL, Sano S, Muralidharan S, Rius C, Vuong J, Jacob S, Muralidhar V, Robertson AA, Cooper MA, Andrés V, Hirschi KK, Martin KA, Walsh K. Clonal hematopoiesis associated with TET2 deficiency accelerates atherosclerosis development in mice. Science. 2017 02 24; 355(6327):842-847.View Related Profiles.

Wu, Chia-Ling
Fuster Ortuno, Jose
Walsh, Kenneth
Zuriaga Herrero, Maria
Maclauchlan, Susan

PMID: 28104796; PMCID: PMC5542057; DOI: 10.1126/science.aag1381;

Farb MG, Karki S, Park SY, Saggese SM, Carmine B, Hess DT, Apovian C, Fetterman JL, Bretón-Romero R, Hamburg NM, Fuster JJ, Zuriaga MA, Walsh K, Gokce N. WNT5A-JNK regulation of vascular insulin resistance in human obesity. Vasc Med. 2016 Dec; 21(6):489-496.View Related Profiles.

Carmine, Brian
Apovian, Caroline
Hess, Donald
Fetterman, Jessica
Fuster Ortuno, Jose
Walsh, Kenneth
Zuriaga Herrero, Maria
Farb, Melissa
Hamburg, Naomi
Gokce, Noyan
Breton-Romero, Rosa
Karki, Shakun

PMID: 27688298; PMCID: PMC5491334; DOI: 10.1177/1358863X16666693;

Maruyama S, Nakamura K, Papanicolaou KN, Sano S, Shimizu I, Asaumi Y, van den Hoff MJ, Ouchi N, Recchia FA, Walsh K. Follistatin-like 1 promotes cardiac fibroblast activation and protects the heart from rupture. EMBO Mol Med. 2016 08; 8(8):949-66.View Related Profiles.

Nakamura, Kazuto
Walsh, Kenneth
Maruyama, Sonomi
Asaumi, Yasuhide

PMID: 27234440; PMCID: PMC4967946; DOI: 10.15252/emmm.201506151;

Lee RT, Walsh K. The Future of Cardiovascular Regenerative Medicine. Circulation. 2016 Jun 21; 133(25):2618-25. PMID: 27324357; PMCID: PMC4918634; DOI: 10.1161/CIRCULATIONAHA.115.019214;

Fuster JJ, Ouchi N, Gokce N, Walsh K. Obesity-Induced Changes in Adipose Tissue Microenvironment and Their Impact on Cardiovascular Disease. Circ Res. 2016 May 27; 118(11):1786-807.View Related Profiles.

Fuster Ortuno, Jose
Walsh, Kenneth
Gokce, Noyan

PMID: 27230642; PMCID: PMC4887147; DOI: 10.1161/CIRCRESAHA.115.306885;

Clark AL, Maruyama S, Sano S, Accorsi A, Girgenrath M, Walsh K, Naya FJ. miR-410 and miR-495 Are Dynamically Regulated in Diverse Cardiomyopathies and Their Inhibition Attenuates Pathological Hypertrophy. PLoS One. 2016; 11(3):e0151515.View Related Profiles.

Walsh, Kenneth
Maruyama, Sonomi

PMID: 26999812; PMCID: PMC4801331; DOI: 10.1371/journal.pone.0151515;

Bretón-Romero R, Feng B, Holbrook M, Farb MG, Fetterman JL, Linder EA, Berk BD, Masaki N, Weisbrod RM, Inagaki E, Gokce N, Fuster JJ, Walsh K, Hamburg NM. Endothelial Dysfunction in Human Diabetes Is Mediated by Wnt5a-JNK Signaling. Arterioscler Thromb Vasc Biol. 2016 Mar; 36(3):561-9.View Related Profiles.

Feng, Bihua
Inagaki, Elica
Fetterman, Jessica
Fuster Ortuno, Jose
Walsh, Kenneth
Farb, Melissa
Holbrook, Monika
Hamburg, Naomi
Gokce, Noyan
Breton-Romero, Rosa

PMID: 26800561; PMCID: PMC4913891; DOI: 10.1161/ATVBAHA.115.306578;

Miller EJ, Calamaras T, Elezaby A, Sverdlov A, Qin F, Luptak I, Wang K, Sun X, Vijay A, Croteau D, Bachschmid M, Cohen RA, Walsh K, Colucci WS. Partial Liver Kinase B1 (LKB1) Deficiency Promotes Diastolic Dysfunction, De Novo Systolic Dysfunction, Apoptosis, and Mitochondrial Dysfunction With Dietary Metabolic Challenge. J Am Heart Assoc. 2015 Dec 31; 5(1).View Related Profiles.

Sverdlov, Aaron
Elezaby, Aly
Qin, Fuzhong
Luptak, Ivan
Walsh, Kenneth
Bachschmid, Markus
Cohen, Richard
Colucci, Wilson

PMID: 26722122; PMCID: PMC4859355; DOI: 10.1161/JAHA.115.002277;

Nakamura K, Sano S, Fuster JJ, Kikuchi R, Shimizu I, Ohshima K, Katanasaka Y, Ouchi N, Walsh K. Secreted Frizzled-related Protein 5 Diminishes Cardiac Inflammation and Protects the Heart from Ischemia/Reperfusion Injury. J Biol Chem. 2016 Feb 5; 291(6):2566-75.View Related Profiles.

Fuster Ortuno, Jose
Nakamura, Kazuto
Walsh, Kenneth
Kikuchi, Ryosuke

PMID: 26631720; PMCID: PMC4742726; DOI: 10.1074/jbc.M115.693937;

Muralidharan S, Sasi SP, Zuriaga MA, Hirschi KK, Porada CD, Coleman MA, Walsh KX, Yan X, Goukassian DA. Corrigendum: Ionizing Particle Radiation as a Modulator of Endogenous Bone Marrow Cell Reprogramming: Implications for Hematological Cancers. Front Oncol. 2015; 5:255.View Related Profiles.

Goukassian, David
Walsh, Kenneth
Zuriaga Herrero, Maria

PMID: 26636037; PMCID: PMC4658418; DOI: 10.3389/fonc.2015.00255;

Cohen Y, Dafni H, Avni R, Fellus L, Bochner F, Rotkopf R, Raz T, Benjamin LE, Walsh K, Neeman M. Genetic and Pharmacological Modulation of Akt1 for Improving Ovarian Graft Revascularization in a Mouse Model. Biol Reprod. 2016 Jan; 94(1):14. PMID: 26490838; DOI: 10.1095/biolreprod.115.131987;

Shah D, Romero F, Zhu Y, Duong M, Sun J, Walsh K, Summer R. C1q Deficiency Promotes Pulmonary Vascular Inflammation and Enhances the Susceptibility of the Lung Endothelium to Injury. J Biol Chem. 2015 Dec 4; 290(49):29642-51. PMID: 26487714; PMCID: PMC4705962; DOI: 10.1074/jbc.M115.690784;

Wei K, Serpooshan V, Hurtado C, Diez-Cuñado M, Zhao M, Maruyama S, Zhu W, Fajardo G, Noseda M, Nakamura K, Tian X, Liu Q, Wang A, Matsuura Y, Bushway P, Cai W, Savchenko A, Mahmoudi M, Schneider MD, van den Hoff MJ, Butte MJ, Yang PC, Walsh K, Zhou B, Bernstein D, Mercola M, Ruiz-Lozano P. Epicardial FSTL1 reconstitution regenerates the adult mammalian heart. Nature. 2015 Sep 24; 525(7570):479-85.View Related Profiles.

Nakamura, Kazuto
Walsh, Kenneth
Maruyama, Sonomi

PMID: 26375005; PMCID: PMC4762253; DOI: 10.1038/nature15372;

Romero F, Shah D, Duong M, Penn RB, Fessler MB, Madenspacher J, Stafstrom W, Kavuru M, Lu B, Kallen CB, Walsh K, Summer R. A pneumocyte-macrophage paracrine lipid axis drives the lung toward fibrosis. Am J Respir Cell Mol Biol. 2015 Jul; 53(1):74-86. PMID: 25409201; PMCID: PMC4566113; DOI: 10.1165/rcmb.2014-0343OC;

Shah D, Romero F, Duong M, Wang N, Paudyal B, Suratt BT, Kallen CB, Sun J, Zhu Y, Walsh K, Summer R. Obesity-induced adipokine imbalance impairs mouse pulmonary vascular endothelial function and primes the lung for injury. Sci Rep. 2015; 5:11362. PMID: 26068229; PMCID: PMC4464323; DOI: 10.1038/srep11362;

Shimizu I, Walsh K. The Whitening of Brown Fat and Its Implications for Weight Management in Obesity. Curr Obes Rep. 2015 Jun; 4(2):224-9. PMID: 26627217; DOI: 10.1007/s13679-015-0157-8;

Kambara T, Shibata R, Ohashi K, Matsuo K, Hiramatsu-Ito M, Enomoto T, Yuasa D, Ito M, Hayakawa S, Ogawa H, Aprahamian T, Walsh K, Murohara T, Ouchi N. C1q/Tumor Necrosis Factor-Related Protein 9 Protects against Acute Myocardial Injury through an Adiponectin Receptor I-AMPK-Dependent Mechanism. Mol Cell Biol. 2015 Jun; 35(12):2173-85.View Related Profiles.

Walsh, Kenneth
Ohashi, Koji
Aprahamian, Tamar

PMID: 25870106; PMCID: PMC4438248; DOI: 10.1128/MCB.01518-14;

Kikuchi R, Nakamura K, MacLauchlan S, Ngo DT, Shimizu I, Fuster JJ, Katanasaka Y, Yoshida S, Qiu Y, Yamaguchi TP, Matsushita T, Murohara T, Gokce N, Bates DO, Hamburg NM, Walsh K. An antiangiogenic isoform of VEGF-A contributes to impaired vascularization in peripheral artery disease. Nat Med. 2014 Dec; 20(12):1464-71.View Related Profiles.

Ngo, Doan
Fuster Ortuno, Jose
Nakamura, Kazuto
Walsh, Kenneth
Hamburg, Naomi
Gokce, Noyan
Kikuchi, Ryosuke
Maclauchlan, Susan

PMID: 25362254; PMCID: PMC4257756; DOI: 10.1038/nm.3703;

Fuster JJ, Zuriaga MA, Ngo DT, Farb MG, Aprahamian T, Yamaguchi TP, Gokce N, Walsh K. Noncanonical Wnt signaling promotes obesity-induced adipose tissue inflammation and metabolic dysfunction independent of adipose tissue expansion. Diabetes. 2015 Apr; 64(4):1235-48.View Related Profiles.

Ngo, Doan
Fuster Ortuno, Jose
Walsh, Kenneth
Zuriaga Herrero, Maria
Farb, Melissa
Gokce, Noyan
Aprahamian, Tamar

PMID: 25352637; PMCID: PMC4375084; DOI: 10.2337/db14-1164;

Yan X, Sasi SP, Gee H, Lee J, Yang Y, Mehrzad R, Onufrak J, Song J, Enderling H, Agarwal A, Rahimi L, Morgan J, Wilson PF, Carrozza J, Walsh K, Kishore R, Goukassian DA. Cardiovascular risks associated with low dose ionizing particle radiation. PLoS One. 2014; 9(10):e110269.View Related Profiles.

Goukassian, David
Carrozza, Joseph
Walsh, Kenneth

PMID: 25337914; PMCID: PMC4206415; DOI: 10.1371/journal.pone.0110269;

Cheng KK, Akasaki Y, Lecommandeur E, Lindsay RT, Murfitt S, Walsh K, Griffin JL. Metabolomic analysis of akt1-mediated muscle hypertrophy in models of diet-induced obesity and age-related fat accumulation. J Proteome Res. 2015 Jan 2; 14(1):342-52. PMID: 25231380; PMCID: PMC4286153; DOI: 10.1021/pr500756u;

Tan PH, Tyrrell HE, Gao L, Xu D, Quan J, Gill D, Rai L, Ding Y, Plant G, Chen Y, Xue JZ, Handa AI, Greenall MJ, Walsh K, Xue SA. Adiponectin receptor signaling on dendritic cells blunts antitumor immunity. Cancer Res. 2014 Oct 15; 74(20):5711-22. PMID: 25261236; PMCID: PMC4314963; DOI: 10.1158/0008-5472.CAN-13-1397;

Dorn GW, Song M, Walsh K. Functional implications of mitofusin 2-mediated mitochondrial-SR tethering. J Mol Cell Cardiol. 2015 Jan; 78:123-8. PMID: 25252175; PMCID: PMC4268321; DOI: 10.1016/j.yjmcc.2014.09.015;

Ngo DT, Farb MG, Kikuchi R, Karki S, Tiwari S, Bigornia SJ, Bates DO, LaValley MP, Hamburg NM, Vita JA, Hess DT, Walsh K, Gokce N. Antiangiogenic actions of vascular endothelial growth factor-A165b, an inhibitory isoform of vascular endothelial growth factor-A, in human obesity. Circulation. 2014 Sep 23; 130(13):1072-80.View Related Profiles.

Ngo, Doan
Hess, Donald
Vita, Joseph
Walsh, Kenneth
Farb, Melissa
LaValley, Michael
Hamburg, Naomi
Gokce, Noyan
Kikuchi, Ryosuke
Karki, Shakun

PMID: 25116954; PMCID: PMC4175289; DOI: 10.1161/CIRCULATIONAHA.113.008171;

Zeng L, Maruyama S, Nakamura K, Parker-Duffen JL, Adham IM, Zhong X, Lee HK, Querfurth H, Walsh K. The injury-induced myokine insulin-like 6 is protective in experimental autoimmune myositis. Skelet Muscle. 2014; 4:16.View Related Profiles.

Nakamura, Kazuto
Walsh, Kenneth
Zeng, Ling
Maruyama, Sonomi
Zhong, Xuemei

PMID: 25161767; PMCID: PMC4144317; DOI: 10.1186/2044-5040-4-16;

Hayakawa S, Ohashi K, Shibata R, Kataoka Y, Miyabe M, Enomoto T, Joki Y, Shimizu Y, Kambara T, Uemura Y, Yuasa D, Ogawa H, Matsuo K, Hiramatsu-Ito M, van den Hoff MJ, Walsh K, Murohara T, Ouchi N. Cardiac myocyte-derived follistatin-like 1 prevents renal injury in a subtotal nephrectomy model. J Am Soc Nephrol. 2015 Mar; 26(3):636-46.View Related Profiles.

Walsh, Kenneth
Ohashi, Koji

PMID: 25071081; PMCID: PMC4341480; DOI: 10.1681/ASN.2014020210;

Hanatani S, Izumiya Y, Araki S, Rokutanda T, Kimura Y, Walsh K, Ogawa H. Akt1-mediated fast/glycolytic skeletal muscle growth attenuates renal damage in experimental kidney disease. J Am Soc Nephrol. 2014 Dec; 25(12):2800-11. PMID: 25012168; PMCID: PMC4243347; DOI: 10.1681/ASN.2013091025;

Yoshida S, Fuster JJ, Walsh K. Adiponectin attenuates abdominal aortic aneurysm formation in hyperlipidemic mice. Atherosclerosis. 2014 Aug; 235(2):339-46.View Related Profiles.

Fuster Ortuno, Jose
Walsh, Kenneth

PMID: 24911638; PMCID: PMC4100794; DOI: 10.1016/j.atherosclerosis.2014.05.923;

Fuster JJ, Walsh K. The good, the bad, and the ugly of interleukin-6 signaling. EMBO J. 2014 Jul 1; 33(13):1425-7.View Related Profiles.

Fuster Ortuno, Jose
Walsh, Kenneth

PMID: 24850773; PMCID: PMC4194086; DOI: 10.15252/embj.201488856;

Parker-Duffen JL, Nakamura K, Silver M, Zuriaga MA, MacLauchlan S, Aprahamian TR, Walsh K. Divergent roles for adiponectin receptor 1 (AdipoR1) and AdipoR2 in mediating revascularization and metabolic dysfunction in vivo. J Biol Chem. 2014 Jun 6; 289(23):16200-13.View Related Profiles.

Nakamura, Kazuto
Walsh, Kenneth
Zuriaga Herrero, Maria
Maclauchlan, Susan
Aprahamian, Tamar

PMID: 24742672; PMCID: PMC4047390; DOI: 10.1074/jbc.M114.548115;

Miyabe M, Ohashi K, Shibata R, Uemura Y, Ogura Y, Yuasa D, Kambara T, Kataoka Y, Yamamoto T, Matsuo K, Joki Y, Enomoto T, Hayakawa S, Hiramatsu-Ito M, Ito M, Van Den Hoff MJ, Walsh K, Murohara T, Ouchi N. Muscle-derived follistatin-like 1 functions to reduce neointimal formation after vascular injury. Cardiovasc Res. 2014 Jul 1; 103(1):111-20.View Related Profiles.

Walsh, Kenneth
Ohashi, Koji

PMID: 24743592; PMCID: PMC4834864; DOI: 10.1093/cvr/cvu105;

Shimizu I, Aprahamian T, Kikuchi R, Shimizu A, Papanicolaou KN, MacLauchlan S, Maruyama S, Walsh K. Vascular rarefaction mediates whitening of brown fat in obesity. J Clin Invest. 2014 May 1; 124(5):2099-112.View Related Profiles.

Shimizu, Ippei
Walsh, Kenneth
Kikuchi, Ryosuke
Maruyama, Sonomi
Maclauchlan, Susan
Aprahamian, Tamar

PMID: 24713652; PMCID: PMC4001539; DOI: 10.1172/JCI71643;

Sasi SP, Song J, Park D, Enderling H, McDonald JT, Gee H, Garrity B, Shtifman A, Yan X, Walsh K, Natarajan M, Kishore R, Goukassian DA. TNF-TNFR2/p75 signaling inhibits early and increases delayed nontargeted effects in bone marrow-derived endothelial progenitor cells. J Biol Chem. 2014 May 16; 289(20):14178-93.View Related Profiles.

Goukassian, David
Walsh, Kenneth

PMID: 24711449; PMCID: PMC4022885; DOI: 10.1074/jbc.M114.567743;

Kwon B, Kumar P, Lee HK, Zeng L, Walsh K, Fu Q, Barakat A, Querfurth HW. Aberrant cell cycle reentry in human and experimental inclusion body myositis and polymyositis. Hum Mol Genet. 2014 Jul 15; 23(14):3681-94. PMID: 24556217; PMCID: PMC4065145; DOI: 10.1093/hmg/ddu077;

Murdoch CE, Shuler M, Haeussler DJ, Kikuchi R, Bearelly P, Han J, Watanabe Y, Fuster JJ, Walsh K, Ho YS, Bachschmid MM, Cohen RA, Matsui R. Glutaredoxin-1 up-regulation induces soluble vascular endothelial growth factor receptor 1, attenuating post-ischemia limb revascularization. J Biol Chem. 2014 Mar 21; 289(12):8633-44.View Related Profiles.

Murdoch, Colin
Haeussler, Dagmar
Han, Jingyan
Fuster Ortuno, Jose
Walsh, Kenneth
Bachschmid, Markus
Matsui, Reiko
Cohen, Richard
Kikuchi, Ryosuke

PMID: 24482236; PMCID: PMC3961686; DOI: 10.1074/jbc.M113.517219;

Nakamura K, Fuster JJ, Walsh K. Adipokines: a link between obesity and cardiovascular disease. J Cardiol. 2014 Apr; 63(4):250-9.View Related Profiles.

Fuster Ortuno, Jose
Nakamura, Kazuto
Walsh, Kenneth

PMID: 24355497; PMCID: PMC3989503; DOI: 10.1016/j.jjcc.2013.11.006;

Uchida S, De Gaspari P, Kostin S, Jenniches K, Kilic A, Izumiya Y, Shiojima I, Grosse Kreymborg K, Renz H, Walsh K, Braun T. Sca1-derived cells are a source of myocardial renewal in the murine adult heart. Stem Cell Reports. 2013; 1(5):397-410. PMID: 24286028; PMCID: PMC3841250; DOI: 10.1016/j.stemcr.2013.09.004;

Akasaki Y, Ouchi N, Izumiya Y, Bernardo BL, Lebrasseur NK, Walsh K. Glycolytic fast-twitch muscle fiber restoration counters adverse age-related changes in body composition and metabolism. Aging Cell. 2014 Feb; 13(1):80-91. PMID: 24033924; PMCID: PMC3947044; DOI: 10.1111/acel.12153;

Parker-Duffen JL, Walsh K. Cardiometabolic effects of adiponectin. Best Pract Res Clin Endocrinol Metab. 2014 Jan; 28(1):81-91.View Related Profiles.

Duffen, Jennifer
Walsh, Kenneth

PMID: 24417948; PMCID: PMC3905311; DOI: 10.1016/j.beem.2013.09.001;

Farb MG, Tiwari S, Karki S, Ngo DT, Carmine B, Hess DT, Zuriaga MA, Walsh K, Fetterman JL, Hamburg NM, Vita JA, Apovian CM, Gokce N. Cyclooxygenase inhibition improves endothelial vasomotor dysfunction of visceral adipose arterioles in human obesity. Obesity (Silver Spring). 2014 Feb; 22(2):349-55.View Related Profiles.

Carmine, Brian
Apovian, Caroline
Ngo, Doan
Hess, Donald
Fetterman, Jessica
Vita, Joseph
Walsh, Kenneth
Zuriaga Herrero, Maria
Farb, Melissa
Hamburg, Naomi
Gokce, Noyan
Karki, Shakun

PMID: 23640904; PMCID: PMC3766380; DOI: 10.1002/oby.20505;

Parker-Duffen JL, Nakamura K, Silver M, Kikuchi R, Tigges U, Yoshida S, Denzel MS, Ranscht B, Walsh K. T-cadherin is essential for adiponectin-mediated revascularization. J Biol Chem. 2013 Aug 23; 288(34):24886-97.View Related Profiles.

Nakamura, Kazuto
Walsh, Kenneth
Kikuchi, Ryosuke

PMID: 23824191; PMCID: PMC3750183; DOI: 10.1074/jbc.M113.454835;

Yoshida S, Aihara K, Ikeda Y, Sumitomo-Ueda Y, Uemoto R, Ishikawa K, Ise T, Yagi S, Iwase T, Mouri Y, Sakari M, Matsumoto T, Takeyama K, Akaike M, Matsumoto M, Sata M, Walsh K, Kato S, Matsumoto T. Androgen receptor promotes sex-independent angiogenesis in response to ischemia and is required for activation of vascular endothelial growth factor receptor signaling. Circulation. 2013 Jul 2; 128(1):60-71. PMID: 23723256; PMCID: PMC3933182; DOI: 10.1161/CIRCULATIONAHA.113.001533;

Shimizu I, Walsh K. Vascular remodeling mediated by Angptl2 produced from perivascular adipose tissue. J Mol Cell Cardiol. 2013 Jun; 59:176-8.View Related Profiles.

Shimizu, Ippei
Walsh, Kenneth

PMID: 23528806; PMCID: PMC3905314; DOI: 10.1016/j.yjmcc.2013.03.009;

Kasumov T, Dabkowski ER, Shekar KC, Li L, Ribeiro RF, Walsh K, Previs SF, Sadygov RG, Willard B, Stanley WC. Assessment of cardiac proteome dynamics with heavy water: slower protein synthesis rates in interfibrillar than subsarcolemmal mitochondria. Am J Physiol Heart Circ Physiol. 2013 May; 304(9):H1201-14. PMID: 23457012; PMCID: PMC3652088; DOI: 10.1152/ajpheart.00933.2012;

Li Y, Wong K, Walsh K, Gao B, Zang M. Retinoic acid receptor ß stimulates hepatic induction of fibroblast growth factor 21 to promote fatty acid oxidation and control whole-body energy homeostasis in mice. J Biol Chem. 2013 Apr 12; 288(15):10490-504.View Related Profiles.

Walsh, Kenneth
Zang, Mengwei
Li, Yu

PMID: 23430257; PMCID: PMC3624431; DOI: 10.1074/jbc.M112.429852;

Papanicolaou KN, Kikuchi R, Ngoh GA, Coughlan KA, Dominguez I, Stanley WC, Walsh K. Mitofusins 1 and 2 are essential for postnatal metabolic remodeling in heart. Circ Res. 2012 Sep 28; 111(8):1012-26.View Related Profiles.

Ngoh, Gladys
Walsh, Kenneth
Coughlan, Kimberly
Dominguez, Maria
Kikuchi, Ryosuke

PMID: 22904094; PMCID: PMC3518037; DOI: 10.1161/CIRCRESAHA.112.274142;

Wanninger J, Liebisch G, Schmitz G, Bauer S, Eisinger K, Neumeier M, Ouchi N, Walsh K, Buechler C. Lipidomic analysis of the liver identifies changes of major and minor lipid species in adiponectin deficient mice. Exp Mol Pathol. 2013 Apr; 94(2):412-7. PMID: 22465357; PMCID: PMC3907090; DOI: 10.1016/j.yexmp.2012.03.008;

Papanicolaou KN, Ngoh GA, Dabkowski ER, O'Connell KA, Ribeiro RF, Stanley WC, Walsh K. Cardiomyocyte deletion of mitofusin-1 leads to mitochondrial fragmentation and improves tolerance to ROS-induced mitochondrial dysfunction and cell death. Am J Physiol Heart Circ Physiol. 2012 Jan 1; 302(1):H167-79.View Related Profiles.

Ngoh, Gladys
Walsh, Kenneth

PMID: 22037195; PMCID: PMC3334239; DOI: 10.1152/ajpheart.00833.2011;

Shimano M, Ouchi N, Nakamura K, van Wijk B, Ohashi K, Asaumi Y, Higuchi A, Pimentel DR, Sam F, Murohara T, van den Hoff MJ, Walsh K. Cardiac myocyte follistatin-like 1 functions to attenuate hypertrophy following pressure overload. Proc Natl Acad Sci U S A. 2011 Oct 25; 108(43):E899-906.View Related Profiles.

Pimentel, David
Sam, Flora
Nakamura, Kazuto
Walsh, Kenneth
Ohashi, Koji
Asaumi, Yasuhide

PMID: 21987816; PMCID: PMC3203781; DOI: 10.1073/pnas.1108559108;

El-Armouche A, Ouchi N, Tanaka K, Doros G, Wittköpper K, Schulze T, Eschenhagen T, Walsh K, Sam F. Follistatin-like 1 in chronic systolic heart failure: a marker of left ventricular remodeling. Circ Heart Fail. 2011 Sep; 4(5):621-7.View Related Profiles.

Sam, Flora
Doros, Gheorghe
Walsh, Kenneth

PMID: 21622850; PMCID: PMC3178753; DOI: 10.1161/CIRCHEARTFAILURE.110.960625;

Papanicolaou KN, Khairallah RJ, Ngoh GA, Chikando A, Luptak I, O'Shea KM, Riley DD, Lugus JJ, Colucci WS, Lederer WJ, Stanley WC, Walsh K. Mitofusin-2 maintains mitochondrial structure and contributes to stress-induced permeability transition in cardiac myocytes. Mol Cell Biol. 2011 Mar; 31(6):1309-28.View Related Profiles.

Ngoh, Gladys
Luptak, Ivan
Lugus, Jesse
Walsh, Kenneth
Colucci, Wilson

PMID: 21245373; PMCID: PMC3067905; DOI: 10.1128/MCB.00911-10;

Shimano M, Ouchi N, Nakamura K, Oshima Y, Higuchi A, Pimentel DR, Panse KD, Lara-Pezzi E, Lee SJ, Sam F, Walsh K. Cardiac myocyte-specific ablation of follistatin-like 3 attenuates stress-induced myocardial hypertrophy. J Biol Chem. 2011 Mar 18; 286(11):9840-8.View Related Profiles.

Pimentel, David
Sam, Flora
Nakamura, Kazuto
Walsh, Kenneth

PMID: 21245136; PMCID: PMC3058981; DOI: 10.1074/jbc.M110.197079;

Ouchi N, Higuchi A, Ohashi K, Oshima Y, Gokce N, Shibata R, Akasaki Y, Shimono A, Walsh K. Sfrp5 is an anti-inflammatory adipokine that modulates metabolic dysfunction in obesity. Science. 2010 Jul 23; 329(5990):454-7.View Related Profiles.

Walsh, Kenneth
Ohashi, Koji
Gokce, Noyan

PMID: 20558665; PMCID: PMC3132938; DOI: 10.1126/science.1188280;

Ikeda Y, Aihara K, Akaike M, Sato T, Ishikawa K, Ise T, Yagi S, Iwase T, Ueda Y, Yoshida S, Azuma H, Walsh K, Tamaki T, Kato S, Matsumoto T. Androgen receptor counteracts Doxorubicin-induced cardiotoxicity in male mice. Mol Endocrinol. 2010 Jul; 24(7):1338-48. PMID: 20501642; PMCID: PMC5417461; DOI: 10.1210/me.2009-0402;

Ohashi K, Ouchi N, Higuchi A, Shaw RJ, Walsh K. LKB1 deficiency in Tie2-Cre-expressing cells impairs ischemia-induced angiogenesis. J Biol Chem. 2010 Jul 16; 285(29):22291-8.View Related Profiles.

Walsh, Kenneth
Ohashi, Koji

PMID: 20489196; PMCID: PMC2903404; DOI: 10.1074/jbc.M110.123794;

Papanicolaou KN, Streicher JM, Ishikawa TO, Herschman H, Wang Y, Walsh K. Preserved heart function and maintained response to cardiac stresses in a genetic model of cardiomyocyte-targeted deficiency of cyclooxygenase-2. J Mol Cell Cardiol. 2010 Aug; 49(2):196-209. PMID: 20399788; PMCID: PMC2891277; DOI: 10.1016/j.yjmcc.2010.04.002;

O'Shea KM, Chess DJ, Khairallah RJ, Rastogi S, Hecker PA, Sabbah HN, Walsh K, Stanley WC. Effects of adiponectin deficiency on structural and metabolic remodeling in mice subjected to pressure overload. Am J Physiol Heart Circ Physiol. 2010 Jun; 298(6):H1639-45. PMID: 20348222; PMCID: PMC2886648; DOI: 10.1152/ajpheart.00957.2009;

Kondo K, Shibata R, Unno K, Shimano M, Ishii M, Kito T, Shintani S, Walsh K, Ouchi N, Murohara T. Impact of a single intracoronary administration of adiponectin on myocardial ischemia/reperfusion injury in a pig model. Circ Cardiovasc Interv. 2010 Apr; 3(2):166-73. PMID: 20332381; PMCID: PMC3668696; DOI: 10.1161/CIRCINTERVENTIONS.109.872044;

Shimano M, Ouchi N, Shibata R, Ohashi K, Pimentel DR, Murohara T, Walsh K. Adiponectin deficiency exacerbates cardiac dysfunction following pressure overload through disruption of an AMPK-dependent angiogenic response. J Mol Cell Cardiol. 2010 Aug; 49(2):210-20.View Related Profiles.

Pimentel, David
Walsh, Kenneth
Ohashi, Koji

PMID: 20206634; PMCID: PMC2885542; DOI: 10.1016/j.yjmcc.2010.02.021;

Biolo A, Shibata R, Ouchi N, Kihara S, Sonoda M, Walsh K, Sam F. Determinants of adiponectin levels in patients with chronic systolic heart failure. Am J Cardiol. 2010 Apr 15; 105(8):1147-52.View Related Profiles.

Sam, Flora
Walsh, Kenneth

PMID: 20381668; PMCID: PMC2854672; DOI: 10.1016/j.amjcard.2009.12.015;

Ouchi N, Asaumi Y, Ohashi K, Higuchi A, Sono-Romanelli S, Oshima Y, Walsh K. DIP2A functions as a FSTL1 receptor. J Biol Chem. 2010 Mar 5; 285(10):7127-34.View Related Profiles.

Walsh, Kenneth
Ohashi, Koji
Asaumi, Yasuhide

PMID: 20054002; PMCID: PMC2844162; DOI: 10.1074/jbc.M109.069468;

Ohashi K, Parker JL, Ouchi N, Higuchi A, Vita JA, Gokce N, Pedersen AA, Kalthoff C, Tullin S, Sams A, Summer R, Walsh K. Adiponectin promotes macrophage polarization toward an anti-inflammatory phenotype. J Biol Chem. 2010 Feb 26; 285(9):6153-60.View Related Profiles.

Vita, Joseph
Walsh, Kenneth
Ohashi, Koji
Gokce, Noyan
Summer, Ross

PMID: 20028977; PMCID: PMC2825410; DOI: 10.1074/jbc.M109.088708;

Ikeda Y, Sato K, Pimentel DR, Sam F, Shaw RJ, Dyck JR, Walsh K. Cardiac-specific deletion of LKB1 leads to hypertrophy and dysfunction. J Biol Chem. 2009 Dec 18; 284(51):35839-49.View Related Profiles.

Pimentel, David
Sam, Flora
Walsh, Kenneth

PMID: 19828446; PMCID: PMC2791013; DOI: 10.1074/jbc.M109.057273;

Sam F, Walsh K. What can adiponectin say about left ventricular function? Heart. 2010 Mar; 96(5):331-2.View Related Profiles.

Sam, Flora
Walsh, Kenneth

PMID: 19934101; PMCID: PMC3673540; DOI: 10.1136/hrt.2009.178590;

Higuchi A, Ohashi K, Shibata R, Sono-Romanelli S, Walsh K, Ouchi N. Thiazolidinediones reduce pathological neovascularization in ischemic retina via an adiponectin-dependent mechanism. Arterioscler Thromb Vasc Biol. 2010 Jan; 30(1):46-53.View Related Profiles.

Walsh, Kenneth
Ohashi, Koji

PMID: 19910632; PMCID: PMC3552615; DOI: 10.1161/ATVBAHA.109.198465;

Sam F, Duhaney TA, Sato K, Wilson RM, Ohashi K, Sono-Romanelli S, Higuchi A, De Silva DS, Qin F, Walsh K, Ouchi N. Adiponectin deficiency, diastolic dysfunction, and diastolic heart failure. Endocrinology. 2010 Jan; 151(1):322-31.View Related Profiles.

Sam, Flora
Qin, Fuzhong
Walsh, Kenneth
Ohashi, Koji

PMID: 19850745; PMCID: PMC2803144; DOI: 10.1210/en.2009-0806;

Oshima Y, Ouchi N, Shimano M, Pimentel DR, Papanicolaou KN, Panse KD, Tsuchida K, Lara-Pezzi E, Lee SJ, Walsh K. Activin A and follistatin-like 3 determine the susceptibility of heart to ischemic injury. Circulation. 2009 Oct 20; 120(16):1606-15.View Related Profiles.

Pimentel, David
Walsh, Kenneth

PMID: 19805648; PMCID: PMC2764796; DOI: 10.1161/CIRCULATIONAHA.109.872200;

Ikeda H, Shiojima I, Ozasa Y, Yoshida M, Holzenberger M, Kahn CR, Walsh K, Igarashi T, Abel ED, Komuro I. Interaction of myocardial insulin receptor and IGF receptor signaling in exercise-induced cardiac hypertrophy. J Mol Cell Cardiol. 2009 Nov; 47(5):664-75. PMID: 19744489; PMCID: PMC4886750; DOI: 10.1016/j.yjmcc.2009.08.028;

Summer R, Fiack CA, Ikeda Y, Sato K, Dwyer D, Ouchi N, Fine A, Farber HW, Walsh K. Adiponectin deficiency: a model of pulmonary hypertension associated with pulmonary vascular disease. Am J Physiol Lung Cell Mol Physiol. 2009 Sep; 297(3):L432-8.View Related Profiles.

Fine, Alan
Farber, Harrison
Walsh, Kenneth
Summer, Ross

PMID: 19561137; PMCID: PMC2739777; DOI: 10.1152/ajplung.90599.2008;

Ohashi K, Ouchi N, Sato K, Higuchi A, Ishikawa TO, Herschman HR, Kihara S, Walsh K. Adiponectin promotes revascularization of ischemic muscle through a cyclooxygenase 2-dependent mechanism. Mol Cell Biol. 2009 Jul; 29(13):3487-99.View Related Profiles.

Walsh, Kenneth
Ohashi, Koji

PMID: 19398582; PMCID: PMC2698754; DOI: 10.1128/MCB.00126-09;

Higuchi A, Ohashi K, Kihara S, Walsh K, Ouchi N. Adiponectin suppresses pathological microvessel formation in retina through modulation of tumor necrosis factor-alpha expression. Circ Res. 2009 May 8; 104(9):1058-65.View Related Profiles.

Walsh, Kenneth
Ohashi, Koji

PMID: 19342600; PMCID: PMC2740643; DOI: 10.1161/CIRCRESAHA.109.194506;

Wang CY, Kim HH, Hiroi Y, Sawada N, Salomone S, Benjamin LE, Walsh K, Moskowitz MA, Liao JK. Obesity increases vascular senescence and susceptibility to ischemic injury through chronic activation of Akt and mTOR. Sci Signal. 2009; 2(62):ra11. PMID: 19293429; PMCID: PMC2667954; DOI: 10.1126/scisignal.2000143;

Peter AK, Ko CY, Kim MH, Hsu N, Ouchi N, Rhie S, Izumiya Y, Zeng L, Walsh K, Crosbie RH. Myogenic Akt signaling upregulates the utrophin-glycoprotein complex and promotes sarcolemma stability in muscular dystrophy. Hum Mol Genet. 2009 Jan 15; 18(2):318-27. PMID: 18986978; PMCID: PMC2638781; DOI: 10.1093/hmg/ddn358;

Ouchi N, Oshima Y, Ohashi K, Higuchi A, Ikegami C, Izumiya Y, Walsh K. Follistatin-like 1, a secreted muscle protein, promotes endothelial cell function and revascularization in ischemic tissue through a nitric-oxide synthase-dependent mechanism. J Biol Chem. 2008 Nov 21; 283(47):32802-11.View Related Profiles.

Walsh, Kenneth
Ohashi, Koji

PMID: 18718903; PMCID: PMC2583310; DOI: 10.1074/jbc.M803440200;

Oshima Y, Ouchi N, Sato K, Izumiya Y, Pimentel DR, Walsh K. Follistatin-like 1 is an Akt-regulated cardioprotective factor that is secreted by the heart. Circulation. 2008 Jun 17; 117(24):3099-108.View Related Profiles.

Pimentel, David
Walsh, Kenneth

PMID: 18519848; PMCID: PMC2679251; DOI: 10.1161/CIRCULATIONAHA.108.767673;

Summer R, Little FF, Ouchi N, Takemura Y, Aprahamian T, Dwyer D, Fitzsimmons K, Suki B, Parameswaran H, Fine A, Walsh K. Alveolar macrophage activation and an emphysema-like phenotype in adiponectin-deficient mice. Am J Physiol Lung Cell Mol Physiol. 2008 Jun; 294(6):L1035-42.View Related Profiles.

Fine, Alan
Suki, Bela
Little, Frederic
Walsh, Kenneth
Aprahamian, Tamar

PMID: 18326826; PMCID: PMC3575679; DOI: 10.1152/ajplung.00397.2007;

Izumiya Y, Hopkins T, Morris C, Sato K, Zeng L, Viereck J, Hamilton JA, Ouchi N, LeBrasseur NK, Walsh K. Fast/Glycolytic muscle fiber growth reduces fat mass and improves metabolic parameters in obese mice. Cell Metab. 2008 Feb; 7(2):159-72.View Related Profiles.

Hamilton, James
Walsh, Kenneth
Zeng, Ling

PMID: 18249175; PMCID: PMC2828690; DOI: 10.1016/j.cmet.2007.11.003;

Takemura Y, Ouchi N, Shibata R, Aprahamian T, Kirber MT, Summer RS, Kihara S, Walsh K. Adiponectin modulates inflammatory reactions via calreticulin receptor-dependent clearance of early apoptotic bodies. J Clin Invest. 2007 Feb; 117(2):375-86.View Related Profiles.

Walsh, Kenneth
Kirber, Michael
Aprahamian, Tamar

PMID: 17256056; PMCID: PMC1770947; DOI: 10.1172/JCI29709;

Phung TL, Ziv K, Dabydeen D, Eyiah-Mensah G, Riveros M, Perruzzi C, Sun J, Monahan-Earley RA, Shiojima I, Nagy JA, Lin MI, Walsh K, Dvorak AM, Briscoe DM, Neeman M, Sessa WC, Dvorak HF, Benjamin LE. Pathological angiogenesis is induced by sustained Akt signaling and inhibited by rapamycin. Cancer Cell. 2006 Aug; 10(2):159-70. PMID: 16904613; PMCID: PMC2531257; DOI: 10.1016/j.ccr.2006.07.003;

Shibata R, Sato K, Pimentel DR, Takemura Y, Kihara S, Ohashi K, Funahashi T, Ouchi N, Walsh K. Adiponectin protects against myocardial ischemia-reperfusion injury through AMPK- and COX-2-dependent mechanisms. Nat Med. 2005 Oct; 11(10):1096-103.View Related Profiles.

Pimentel, David
Walsh, Kenneth
Ohashi, Koji

PMID: 16155579; PMCID: PMC2828682; DOI: 10.1038/nm1295;

Shiojima I, Sato K, Izumiya Y, Schiekofer S, Ito M, Liao R, Colucci WS, Walsh K. Disruption of coordinated cardiac hypertrophy and angiogenesis contributes to the transition to heart failure. J Clin Invest. 2005 Aug; 115(8):2108-18.View Related Profiles.

Walsh, Kenneth
Colucci, Wilson

PMID: 16075055; PMCID: PMC1180541; DOI: 10.1172/JCI24682;

Ackah E, Yu J, Zoellner S, Iwakiri Y, Skurk C, Shibata R, Ouchi N, Easton RM, Galasso G, Birnbaum MJ, Walsh K, Sessa WC. Akt1/protein kinase Balpha is critical for ischemic and VEGF-mediated angiogenesis. J Clin Invest. 2005 Aug; 115(8):2119-27. PMID: 16075056; PMCID: PMC1180542; DOI: 10.1172/JCI24726;

Skurk C, Izumiya Y, Maatz H, Razeghi P, Shiojima I, Sandri M, Sato K, Zeng L, Schiekofer S, Pimentel D, Lecker S, Taegtmeyer H, Goldberg AL, Walsh K. The FOXO3a transcription factor regulates cardiac myocyte size downstream of AKT signaling. J Biol Chem. 2005 May 27; 280(21):20814-23.View Related Profiles.

Pimentel, David
Walsh, Kenneth
Zeng, Ling

PMID: 15781459; PMCID: PMC3632436; DOI: 10.1074/jbc.M500528200;

Sun JF, Phung T, Shiojima I, Felske T, Upalakalin JN, Feng D, Kornaga T, Dor T, Dvorak AM, Walsh K, Benjamin LE. Microvascular patterning is controlled by fine-tuning the Akt signal. Proc Natl Acad Sci U S A. 2005 Jan 4; 102(1):128-33. PMID: 15611473; PMCID: PMC538747

Shibata R, Ouchi N, Ito M, Kihara S, Shiojima I, Pimentel DR, Kumada M, Sato K, Schiekofer S, Ohashi K, Funahashi T, Colucci WS, Walsh K. Adiponectin-mediated modulation of hypertrophic signals in the heart. Nat Med. 2004 Dec; 10(12):1384-9.View Related Profiles.

Pimentel, David
Walsh, Kenneth
Ohashi, Koji
Colucci, Wilson

PMID: 15558058; PMCID: PMC2828675

Sandri M, Sandri C, Gilbert A, Skurk C, Calabria E, Picard A, Walsh K, Schiaffino S, Lecker SH, Goldberg AL. Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy. Cell. 2004 Apr 30; 117(3):399-412. PMID: 15109499; PMCID: PMC3619734

Aprahamian T, Rifkin I, Bonegio R, Hugel B, Freyssinet JM, Sato K, Castellot JJ, Walsh K. Impaired clearance of apoptotic cells promotes synergy between atherogenesis and autoimmune disease. J Exp Med. 2004 Apr 19; 199(8):1121-31.View Related Profiles.

Rifkin, Ian
Walsh, Kenneth
Bonegio, Ramon
Aprahamian, Tamar

PMID: 15096538; PMCID: PMC2211887

Takahashi A, Kureishi Y, Yang J, Luo Z, Guo K, Mukhopadhyay D, Ivashchenko Y, Branellec D, Walsh K. Myogenic Akt signaling regulates blood vessel recruitment during myofiber growth. Mol Cell Biol. 2002 Jul; 22(13):4803-14. PMID: 12052887; PMCID: PMC133891

Kureishi Y, Luo Z, Shiojima I, Bialik A, Fulton D, Lefer DJ, Sessa WC, Walsh K. The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals. Nat Med. 2000 Sep; 6(9):1004-10. PMID: 10973320; PMCID: PMC2828689

Maillard L, Van Belle E, Tio FO, Rivard A, Kearney M, Branellec D, Steg PG, Isner JM, Walsh K. Effect of percutaneous adenovirus-mediated Gax gene delivery to the arterial wall in double-injured atheromatous stented rabbit iliac arteries. Gene Ther. 2000 Aug; 7(16):1353-61. PMID: 10981661

Luo Z, Fujio Y, Kureishi Y, Rudic RD, Daumerie G, Fulton D, Sessa WC, Walsh K. Acute modulation of endothelial Akt/PKB activity alters nitric oxide-dependent vasomotor activity in vivo. J Clin Invest. 2000 Aug; 106(4):493-9. PMID: 10953024; PMCID: PMC380252

Fujio Y, Nguyen T, Wencker D, Kitsis RN, Walsh K. Akt promotes survival of cardiomyocytes in vitro and protects against ischemia-reperfusion injury in mouse heart. Circulation. 2000 Feb 15; 101(6):660-7. PMID: 10673259; PMCID: PMC3627349

Fulton D, Gratton JP, McCabe TJ, Fontana J, Fujio Y, Walsh K, Franke TF, Papapetropoulos A, Sessa WC. Regulation of endothelium-derived nitric oxide production by the protein kinase Akt. Nature. 1999 Jun 10; 399(6736):597-601. PMID: 10376602; PMCID: PMC3637917

Fujio Y, Walsh K. Akt mediates cytoprotection of endothelial cells by vascular endothelial growth factor in an anchorage-dependent manner. J Biol Chem. 1999 Jun 4; 274(23):16349-54. PMID: 10347193; PMCID: PMC3624707

Amant C, Berthou L, Walsh K. Angiogenesis and gene therapy in man: dream or reality? Drugs. 1999; 58 Spec No 1:33-6. PMID: 10526956

Sata M, Walsh K. Oxidized LDL activates fas-mediated endothelial cell apoptosis. J Clin Invest. 1998 Nov 1; 102(9):1682-9. PMID: 9802882; PMCID: PMC509116

Sata M, Walsh K. TNFalpha regulation of Fas ligand expression on the vascular endothelium modulates leukocyte extravasation. Nat Med. 1998 Apr; 4(4):415-20. PMID: 9546786; PMCID: PMC2828686

Martin KA, Gualberto A, Kolman MF, Lowry J, Walsh K. A competitive mechanism of CArG element regulation by YY1 and SRF: implications for assessment of Phox1/MHox transcription factor interactions at CArG elements. DNA Cell Biol. 1997 May; 16(5):653-61. PMID: 9174170

Wang J, Walsh K. Resistance to apoptosis conferred by Cdk inhibitors during myocyte differentiation. Science. 1996 Jul 19; 273(5273):359-61. PMID: 8662523; PMCID: PMC3641673

Walsh K. Cross-binding of factors to functionally different promoter elements in c-fos and skeletal actin genes. Mol Cell Biol. 1989 May; 9(5):2191-201. PMID: 2501661; PMCID: PMC363013

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

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