Kenneth Walsh, PhD
Adjunct Professor
Boston University School of Medicine
Dept of Medicine
Cardiovascular Medicine

PhD, University of California, Berkeley




My laboratory examines molecular events that drive cardiovascular cell growth, differentiation and apoptosis. Over the past decade my laboratory has been investigating mechanisms of inter-tissue communication and how these systems contribute to physiological versus pathological tissue growth in the cardiovascular system.

Member
Boston University
Evans Center for Interdisciplinary Biomedical Research


Graduate Faculty (Primary Mentor of Grad Students)
Boston University School of Medicine, Graduate Medical Sciences


Director of Whitaker Cardiovascular Institute
Boston University School of Medicine



2011 Distinguished Investigator of the American Heart Association
2008-2018 Aram V. Chobanian Distinguished Professor of Medicine
2003-2013 National Advisory Council on Aging, National Institute on Aging: Method to Extend Research in Time (MERIT) Award
2001-2018 American Heart Association: Fellow, Council on Basic Cardiovascular Research
1997 BGSU: Chemistry Alumnus of the Year
1996-1999 Gencell Investigator
1995 Case Western Reserve University: Division of Nephrology Visiting Professor
1993 Molecular and Cellular Biology of the Vascular Wall: AHA Young Investigator Award
1993 AHA Council on Arteriosclerosis: Irvine F. Page Young Investigator Award
1990-1995 Established Investigator of the American Heart Association
1990-1992 Life and Health Insurance Medical Research Fund Award
1989-1993 Mathers Foundation Young Investigator
1988-1989 National Research Service Award Fellowship
1987-1988 National Research Service Award Fellowship
1986-1987 Muscular Dystrophy Association: Postdoctoral Fellowship


Wnt signaling control of vascular phenotype in obesity
08/16/2019 - 07/31/2024 (Multi-PI)
PI: Kenneth Walsh, PhD
NIH/National Heart, Lung, and Blood Institute
1R01HL142650-01A1

Anti-Angiogenic Mechanisms in Human Obesity
11/14/2014 - 10/31/2020 (Multi-PI)
PI: Kenneth Walsh, PhD
NIH/National Heart, Lung, and Blood Institute
5R01HL126141-05

Myokine Control of Hepatic Steatosis
09/15/2016 - 05/31/2018 (PI)
NIH/National Institute on Aging
5R21AG052160-02

Inflammatory Pathways in Aortic Aneurysms
04/01/2016 - 04/12/2018 (PI)
NIH/National Heart, Lung, and Blood Institute
5R01HL132564-03

Somatic TET2 mutations in cardiac remodeling
07/15/2017 - 03/31/2018 (PI)
NIH/National Heart, Lung, and Blood Institute
1R01HL138014-01

Follistatin-like protein 1 in cardiac and systemic metabolism
04/01/2016 - 03/31/2018 (Subcontract PI)
Temple University of the Commonwealth System of Higher Education NIH NHLBI
5R01HL129120-02

Inflammatory Wnt signaling in ischemic myocardium
01/01/2016 - 03/31/2018 (PI)
NIH/National Heart, Lung, and Blood Institute
5R01HL131006-03

Cardio-metabolic actions of FSTL1
03/28/2013 - 09/30/2017 (PI)
Takeda Pharmaceuticals North America, Inc.


Paracrine Regulation of Heart Failure
07/01/2016 - 06/30/2017 (PI)
NIH/National Heart, Lung, and Blood Institute
4R01HL116591-04

Mitochondrial Dynamics and Cardiac Remodeling
06/01/2016 - 05/31/2017 (PI)
NIH/National Heart, Lung, and Blood Institute
4R01HL120160-04

Showing 10 of 33 results. Show All Results


Title


Yr Title Project-Sub Proj Pubs
2020 Clonal hematopoiesis and accelerated metabolic dysfunction in obesity 5R01HL139819-02 2
2020 Clonal hematopoiesis and accelerated metabolic dysfunction in obesity 5R01HL139819-02 2
2020 Hematopoietic stem cell mutations and ischemic cardio-metabolic disease 5R01HL141256-02 1
2019 Wnt signaling control of vascular phenotype in obesity 1R01HL142650-01A1
2019 Clonal hematopoiesis and accelerated metabolic dysfunction in obesity 1R01HL139819-01A1 2
2019 Hematopoietic stem cell mutations and ischemic cardio-metabolic disease 1R01HL141256-01A1 1
2019 Somatic TET2 mutations in cardiac remodeling 5R01HL138014-04 5
2019 Follistatin-like protein 1 in cardiac and systemic metabolism 5R01HL129120-04 8
2019 Inflammatory Pathways in Aortic Aneurysms 5R01HL132564-05 14
2019 Inflammatory Wnt signaling in ischemic myocardium 5R01HL131006-05 20
Showing 10 of 153 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Shah SA, Cui SX, Waters CD, Sano S, Wang Y, Doviak H, Leor J, Walsh K, French BA, Epstein FH. Nitroxide-enhanced MRI of cardiovascular oxidative stress. NMR Biomed. 2020 Jul 09; e4359. PMID: 32648316
     
  2. Jung C, Evans MA, Walsh K. Genetics of age-related clonal hematopoiesis and atherosclerotic cardiovascular disease. Curr Opin Cardiol. 2020 May; 35(3):219-225. PMID: 32073406
     
  3. Wang Y, Sano S, Yura Y, Ke Z, Sano M, Oshima K, Ogawa H, Horitani K, Min KD, Miura-Yura E, Kour A, Evans MA, Zuriaga MA, Hirschi KK, Fuster JJ, Pietras EM, Walsh K. Tet2-mediated clonal hematopoiesis in nonconditioned mice accelerates age-associated cardiac dysfunction. JCI Insight. 2020 Mar 26; 5(6). PMID: 32154790
     
  4. Yura Y, Sano S, Walsh K. Clonal Hematopoiesis: A New Step Linking Inflammation to Heart Failure. JACC Basic Transl Sci. 2020 Feb; 5(2):196-207. PMID: 32140625
     
  5. Sano S, Wang Y, Walsh K. Somatic mosaicism: implications for the cardiovascular system. Eur Heart J. 2019 Dec 26. PMID: 31876923
     
  6. Evans MA, Sano S, Walsh K. Cardiovascular Disease, Aging, and Clonal Hematopoiesis. Annu Rev Pathol. 2020 01 24; 15:419-438. PMID: 31689371
     
  7. Sano S, Wang Y, Evans MA, Yura Y, Sano M, Ogawa H, Horitani K, Doviak H, Walsh K. Lentiviral CRISPR/Cas9-Mediated Genome Editing for the Study of Hematopoietic Cells in Disease Models. J Vis Exp. 2019 10 03; (152). PMID: 31633690
     
  8. Sano S, Wang Y, Yura Y, Sano M, Oshima K, Yang Y, Katanasaka Y, Min KD, Matsuura S, Ravid K, Mohi G, Walsh K. JAK2V617F -Mediated Clonal Hematopoiesis Accelerates Pathological Remodeling in Murine Heart Failure. JACC Basic Transl Sci. 2019 Oct; 4(6):684-697.View Related Profiles. PMID: 31709318; DOI: 10.1016/j.jacbts.2019.05.013;
     
  9. Wang Y, Sano S, Oshima K, Sano M, Watanabe Y, Katanasaka Y, Yura Y, Jung C, Anzai A, Swirski FK, Gokce N, Walsh K. Wnt5a-Mediated Neutrophil Recruitment Has an Obligatory Role in Pressure Overload-Induced Cardiac Dysfunction. Circulation. 2019 08 06; 140(6):487-499.View Related Profiles. PMID: 31170826
     
  10. Kivelä R, Hemanthakumar KA, Vaparanta K, Robciuc M, Izumiya Y, Kidoya H, Takakura N, Peng X, Sawyer DB, Elenius K, Walsh K, Alitalo K. Endothelial Cells Regulate Physiological Cardiomyocyte Growth via VEGFR2-Mediated Paracrine Signaling. Circulation. 2019 05 28; 139(22):2570-2584. PMID: 30922063
     
Showing 10 of 127 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 127 publications over 24 distinct years, with a maximum of 18 publications in 2014

YearPublications
19891
19961
19971
19982
19993
20004
20021
20044
20054
20061
20071
20085
200911
20109
20115
20122
201310
201418
201510
20166
201711
20186
20197
20204

In addition to these self-described keywords below, a list of MeSH based concepts is available here.

apoptosis
cardiovascular system
cell differentiation
cell growth
inter-tissue communication
Contact for Mentoring:

700 Albany St Ctr for Adv Biomed Res
Boston MA 02118
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