Jesse B. Mez, MD
Associate Professor
Boston University School of Medicine
Dept of Neurology

MD, University of Maryland School of Medicine
MS, Columbia University School of Public Health




Dr. Mez completed his undergraduate studies at Cornell University and earned his medical degree from the University of Maryland School of Medicine. He completed residency training in Neurology at Massachusetts General and Brigham and Women’s Hospitals. He completed a clinical fellowship in Aging and Dementia and a research fellowship in Neuroepidemiology at Columbia University. During fellowship training, he also earned a Masters in Biostatistics with a focus on Statistical Genetics from the Mailman School of Public Health at Columbia. In 2013, he became an Assistant Professor of Neurology at Boston University (BU) School of Medicine. In 2014, he became Associate Director of the BU Alzheimer's Disease Center (ADC) Clinical Core.

Investigator
Framingham Heart Study


Member
Boston University
Evans Center for Interdisciplinary Biomedical Research



2015 Alzheimer’s Association New Investigator Award
2014 Junior Faculty Spivack Neuroscience Scholar
2013 BU ADC Pilot Grant
2011 NIH Clinical Research Loan Repayment Program recipient
2002 National Student Research Forum grant
2002 Maryland House of Delegates Graduate Scholarship recipient


ADNI Psychometrics
12/01/2017 - 03/31/2022 (Subcontract PI)
University of Washington NIH NIA
5R01AG029672-09

Leveraging Existing Aging Research Networks to investigate TBI and AD/ADRD risk (LEARN TBI & AD)
03/15/2019 - 11/30/2021 (Subcontract PI)
Icahn School of Medicine at Mount Sinai NIH NIA
5R01AG061028-03

Leveraging the Framingham Study to Investigate Relationships between Traumatic Brain Injury, Military Service, Alzheimer's Disease and Related Dementias
09/01/2018 - 08/31/2021 (PI)
Department of Defense/Army Medical Research Acquisition Activity


Genetic Architecture of Memory and Executive Functioning in Alzheimer's Disease
09/01/2014 - 05/31/2019 (Co-Investigator)
University of Washington NIH NIA
5R01AG042437-04

Genetic and Neuropsychological Heterogeneity in Alzheimer's Disease
08/15/2014 - 05/31/2019 (PI)
NIH/National Institute on Aging
5K23AG046377-05

Exploring MAPT and tau-related genes in chonic traumatic encephalopathy
10/01/2015 - 09/30/2017 (PI)
Alzheimer's Association




Title


Yr Title Project-Sub Proj Pubs
2021 Core B: Clinical Core 1P30AG072978-01-9742
2021 Clinicopathological Correlation in Chronic Traumatic Encephalopathy (CTE) and Chronic Traumatic Brain Injury (cTBI) 5U54NS115266-03-6601
2021 Leveraging Existing Aging Research Networks to investigate TBI and AD/ADRD risk (LEARN TBI & AD) 5R01AG061028-03 2
2020 Clinicopathological Correlation in Chronic Traumatic Encephalopathy (CTE) and Chronic Traumatic Brain Injury (cTBI) 5U54NS115266-02-6601
2020 Leveraging Existing Aging Research Networks to investigate TBI and AD/ADRD risk (LEARN TBI & AD) 5R01AG061028-02 2
2019 Core B: Clinical Core 5P30AG013846-23-6895 874
2019 Leveraging Existing Aging Research Networks to investigate TBI and AD/ADRD risk (LEARN TBI & AD) 1R01AG061028-01 2
2019 Clinicopathological Correlation in Chronic Traumatic Encephalopathy (CTE) and Chronic Traumatic Brain Injury (cTBI) 1U54NS115266-01-6601
2018 Genetic and Neuropsychological Heterogeneity in Alzheimer's Disease 5K23AG046377-05 33
2017 Genetic and Neuropsychological Heterogeneity in Alzheimer's Disease 5K23AG046377-04 33
Showing 10 of 13 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Uretsky M, Gibbons LE, Mukherjee S, Trittschuh EH, Fardo DW, Boyle PA, Keene CD, Saykin AJ, Crane PK, Schneider JA, Mez J. Longitudinal cognitive performance of Alzheimer's disease neuropathological subtypes. Alzheimers Dement (N Y). 2021; 7(1):e12201. PMID: 34604500; PMCID: PMC8474122; DOI: 10.1002/trc2.12201;
     
  2. Cherry JD, Agus F, Dixon E, Huber B, Alvarez VE, Mez J, McKee AC, Labadorf A, Stein TD. Differential gene expression in the cortical sulcus compared to the gyral crest within the early stages of chronic traumatic encephalopathy. Free Neuropathol. 2021; 2.View Related Profiles. PMID: 34485990; PMCID: PMC8415801; DOI: 10.17879/freeneuropathology-2021-3453;
     
  3. Alosco ML, Mariani ML, Adler CH, Balcer LJ, Bernick C, Au R, Banks SJ, Barr WB, Bouix S, Cantu RC, Coleman MJ, Dodick DW, Farrer LA, Geda YE, Katz DI, Koerte IK, Kowall NW, Lin AP, Marcus DS, Marek KL, McClean MD, McKee AC, Mez J, Palmisano JN, Peskind ER, Tripodis Y, Turner RW, Wethe JV, Cummings JL, Reiman EM, Shenton ME, Stern RA. Developing methods to detect and diagnose chronic traumatic encephalopathy during life: rationale, design, and methodology for the DIAGNOSE CTE Research Project. Alzheimers Res Ther. 2021 08 12; 13(1):136.View Related Profiles. PMID: 34384490; PMCID: PMC8357968; DOI: 10.1186/s13195-021-00872-x;
     
  4. Mez J, Alosco ML, Nowinski CJ, McKee AC, Tripodis Y. Reader Response: Association of Position Played and Career Duration and Chronic Traumatic Encephalopathy at Autopsy in Elite Football and Hockey Players. Neurology. 2021 08 10; 97(6):297-298.View Related Profiles. PMID: 34373356; DOI: 10.1212/WNL.0000000000012381;
     
  5. Tao Q, Alvin Ang TF, Akhter-Khan SC, Itchapurapu IS, Killiany R, Zhang X, Budson AE, Turk KW, Goldstein L, Mez J, Alosco ML, Qiu WQ. Impact of C-Reactive Protein on Cognition and Alzheimer Disease Biomarkers in Homozygous Apolipoprotein E ?4 Carriers. Neurology. 2021 Jul 15.View Related Profiles. PMID: 34266923
     
  6. Groot C, Risacher SL, Chen JQA, Dicks E, Saykin AJ, Mac Donald CL, Mez J, Trittschuh EH, Mukherjee S, Barkhof F, Scheltens P, van der Flier WM, Ossenkoppele R, Crane PK. Differential trajectories of hypometabolism across cognitively-defined Alzheimer's disease subgroups. Neuroimage Clin. 2021; 31:102725. PMID: 34153688; PMCID: PMC8238088; DOI: 10.1016/j.nicl.2021.102725;
     
  7. Alosco ML, Culhane J, Mez J. Neuroimaging Biomarkers of Chronic Traumatic Encephalopathy: Targets for the Academic Memory Disorders Clinic. Neurotherapeutics. 2021 04; 18(2):772-791.View Related Profiles. PMID: 33847906
     
  8. Mez J, Alosco ML, Daneshvar DH, Saltiel N, Baucom Z, Abdolmohammadi B, Uretsky M, Nicks R, Martin BM, Palmisano JN, Nowinski CJ, Montenigro P, Solomon TM, Mahar I, Cherry JD, Alvarez VE, Dwyer B, Goldstein LE, Katz DI, Cantu RC, Kowall NW, Tripodis Y, Huber BR, Stein TD, Stern RA, McKee AC. Validity of the 2014 traumatic encephalopathy syndrome criteria for CTE pathology. Alzheimers Dement. 2021 Apr 07.View Related Profiles. PMID: 33826224
     
  9. Groot C, Grothe MJ, Mukherjee S, Jelistratova I, Jansen I, van Loenhoud AC, Risacher SL, Saykin AJ, Mac Donald CL, Mez J, Trittschuh EH, Gryglewski G, Lanzenberger R, Pijnenburg YAL, Barkhof F, Scheltens P, van der Flier WM, Crane PK, Ossenkoppele R. Differential patterns of gray matter volumes and associated gene expression profiles in cognitively-defined Alzheimer's disease subgroups. Neuroimage Clin. 2021; 30:102660. PMID: 33895633; PMCID: PMC8186562; DOI: 10.1016/j.nicl.2021.102660;
     
  10. Akhter-Khan SC, Tao Q, Ang TFA, Itchapurapu IS, Alosco ML, Mez J, Piers RJ, Steffens DC, Au R, Qiu WQ. Associations of loneliness with risk of Alzheimer's disease dementia in the Framingham Heart Study. Alzheimers Dement. 2021 Mar 24.View Related Profiles. PMID: 33760348
     
Showing 10 of 81 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 81 publications over 13 distinct years, with a maximum of 18 publications in 2020

YearPublications
20041
20071
20091
20101
20135
20141
20155
20168
20179
20187
201911
202018
202113


BU Researchers: CTE Study Offers Potential Path For Diagnosing The Brain Disease Before Death

WBUR 4/7/2021

Each Year You Play Football Increases Your Chances of Developing CTE by 30 Percent

League of Fans 10/29/2020

Soccer Heading Has Greater Impact on Memory in ApoE4 Carriers

Alzforum 1/31/2020

Soccer Headers Might Be More Risky for APOE4 Genotype Carriers

Medscape 1/30/2020

Pointed ‘Tackle Can Wait’ TV ad hits amid sobering new CTE study’s stats

Sporting News 10/14/2019

Every 2.6 Years of Playing American Football Doubles Risk of Devastating Brain Disease

ZME Science 10/9/2019

NFL Stars' Risk of Developing the Degenerative Brain Disease CTE Soars by a THIRD Every Year They Play, Study Finds

Daily Mail 10/8/2019

Scary: Study Finds Every Year of Tackle Football Raises Chances of CTE 30%

The Daily Wire 10/8/2019

NFL stars’ risk of developing the degenerative brain disease CTE soars by a THIRD every year they play, study finds

Daily Mail 10/8/2019

CTE Risk Goes Up 30% For Each Year Of Playing Football

Futurity 10/8/2019

BU Research Finds Link Between Playing Football and CTE

WHDH 10/8/2019

CTE Risk in Football Players Doubles Every Five Years, New Study Finds

Boston Magazine 10/7/2019

CTE Risk More Than Doubles after Just Three Years of Playing Football

BU Today 10/7/2019

CTE Risk, Severity Increases With Years Playing Football, Study Shows

Boston Herald 10/7/2019

College Football Season Is Here. Will Universities Continue To Ignore The Risk Of Brain Damage?

Forbes 9/2/2019

New Jersey Unveils New Limits on High School Football Practices

The New York Times 2/13/2019

Cannabis Studied to Treat Conditions from Football-Related Brain Trauma

WeedMaps 2/4/2019

Why We Still Don’t Know How Many NFL Players Have CTE

Five Thirty Eight 12/17/2018

What's the Risk of Chronic Traumatic Encephalopathy for NFL Players?

Inside Science 11/29/2018

Some People May Have Increased CTE Risk Because Of Their Genes

Inquisitr 11/4/2018

Why Some People’s CTE Symptoms Are More Severe Than Others

BU Today 11/3/2018

Why do some people get CTE? It may be in their genes

CNN Todau 11/3/2018

Why Don't All Football Players Develop CTE? It May Be Genetics

WBGH 11/3/2018

MED Researchers: Youth Football Linked to Earlier Brain Problems

BU Today 4/30/2018
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