Jesse B. Mez, MD
Associate Professor
Boston University Chobanian & Avedisian School of Medicine
Neurology

MD, University of Maryland School of Medicine
MS, Columbia University School of Public Health
BS, Cornell University



Dr. Mez completed his undergraduate studies at Cornell University and earned his medical degree from the University of Maryland School of Medicine. He completed residency training in Neurology at Massachusetts General and Brigham and Women’s Hospitals. He completed a clinical fellowship in Aging and Dementia and a research fellowship in Neuroepidemiology at Columbia University. During fellowship training, he also earned a Masters in Biostatistics with a focus on Statistical Genetics from the Mailman School of Public Health at Columbia. In 2013, he became an Assistant Professor of Neurology at Boston University (BU) School of Medicine. In 2014, he became Associate Director of the BU Alzheimer's Disease Center (ADC) Clinical Core.

Investigator
Framingham Heart Study


Member
Boston University
Evans Center for Interdisciplinary Biomedical Research




Validation of Lens Beta-Amyloid as a Novel Biomarker for Early Detection of Alzheimer's Disease at the Boston University Alzheimer's Disease Research
09/30/2023 - 06/30/2028 (Multi-PI)
PI: Jesse B. Mez, MD
NIH/National Institute on Aging
1R01AG077588-01A1

Boston University Alzheimer's Disease Research Center
08/15/2021 - 06/30/2026 (Key Person)
PI: Ann C. McKee, MD
NIH/National Institute on Aging
5P30AG072978-03

Protocol number BAN2401-G000-303: AHEAD 3-45 Study: A Placebo-Controlled, Double-Blind, Parallel-Treatment Arm, 216 Week Study to Evaluate Efficacy and Safety of Treatment With BAN2401 in Subject
01/01/2020 - 12/31/2024 (PI of Sub-Project / SP)
University of Southern California Eisai, Inc


Leveraging Existing Aging Research Networks to investigate TBI and AD/ADRD risk (LEARN TBI & AD)
03/15/2019 - 11/30/2024 (Multi-PI)
PI: Jesse B. Mez, MD
Icahn School of Medicine at Mount Sinai NIH NIA
5R01AG061028-05S1

Alzheimer's Disease Sequencing Project Phenotype Harmonization Consortium
09/30/2021 - 08/31/2024 (Subcontract PI)
Vanderbilt University Medical Center NIH NIA
5U24AG074855-02

AHEAD Plasma Extension (APEX)
05/01/2023 - 04/30/2024 (Subcontract PI)
University of Southern California NIH NIA
5R01AG053798-05

Leveraging the Framingham Study to Investigate Relationships between Traumatic Brain Injury, Military Service, Alzheimer's Disease and Related Dementias
09/01/2018 - 08/31/2023 (PI)
Department of Defense/Army Medical Research Acquisition Activity


ADNI Psychometrics
12/01/2017 - 03/31/2023 (Subcontract PI)
University of Washington NIH NIA
5R01AG029672-10

Genetic Architecture of Memory and Executive Functioning in Alzheimer's Disease
09/01/2014 - 05/31/2019 (Co-Investigator)
University of Washington NIH NIA
5R01AG042437-04

Genetic and Neuropsychological Heterogeneity in Alzheimer's Disease
08/15/2014 - 05/31/2019 (PI)
NIH/National Institute on Aging
5K23AG046377-05

Showing 10 of 12 results. Show All Results


Title


Yr Title Project-Sub Proj Pubs
2023 Validation of Lens Beta-Amyloid as a Novel Biomarker for Early Detection of Alzheimer's Disease at the Boston University Alzheimer's Disease Research 1R01AG077588-01A1
2023 Core B: Clinical Core 5P30AG072978-03-9742
2023 Clinicopathological Correlation in Chronic Traumatic Encephalopathy (CTE) and Chronic Traumatic Brain Injury (cTBI) 5U54NS115266-05-6543
2023 Leveraging Existing Aging Research Networks to investigate TBI and AD/ADRD risk (LEARN TBI & AD) 3R01AG061028-05S1
2023 Leveraging Existing Aging Research Networks to investigate TBI and AD/ADRD risk (LEARN TBI & AD) 5R01AG061028-05
2022 Core B: Clinical Core 5P30AG072978-02-9742
2022 Clinicopathological Correlation in Chronic Traumatic Encephalopathy (CTE) and Chronic Traumatic Brain Injury (cTBI) 5U54NS115266-04-6601
2022 Leveraging Existing Aging Research Networks to investigate TBI and AD/ADRD risk (LEARN TBI & AD) 5R01AG061028-04
2021 Core B: Clinical Core 1P30AG072978-01-9742
2021 Clinicopathological Correlation in Chronic Traumatic Encephalopathy (CTE) and Chronic Traumatic Brain Injury (cTBI) 5U54NS115266-03-6601
Showing 10 of 21 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Culhane JE, Jackson CE, Tripodis Y, Nowinski CJ, Dams-O'Connor K, Pettway E, Uretsky M, Abdolmohammadi B, Nair E, Martin B, Palmisano J, Katz DI, Dwyer B, Daneshvar DH, Goldstein LE, Kowall NW, Cantu RC, Stern RA, Huber BR, Crary JF, Mez J, Stein TD, McKee AC, Alosco ML. Lack of Association of Informant-Reported Traumatic Brain Injury and Chronic Traumatic Encephalopathy. J Neurotrauma. 2024 Apr 15.View Related Profiles. PMID: 38445389
     
  2. Banks SJ, Yhang E, Tripodis Y, Su Y, Protas H, Adler CH, Balcer LJ, Bernick C, Mez JB, Palmisano J, Barr WB, Wethe JV, Dodick DW, Mcclean MD, Martin B, Hartlage K, Turner A, Turner RW, Malhotra A, Colman M, Pasternak O, Lin AP, Koerte IK, Bouix S, Cummings JL, Shenton ME, Reiman EM, Stern RA, Alosco ML. Clinical Outcomes and Tau Pathology in Retired Football Players: Associations With Diagnosed and Witnessed Sleep Apnea. Neurol Clin Pract. 2024 Apr; 14(2):e200263.View Related Profiles. PMID: 38425491; PMCID: PMC10900387; DOI: 10.1212/CPJ.0000000000200263;
     
  3. Alexander A, Alvarez VE, Huber BR, Alosco ML, Mez J, Tripodis Y, Nicks R, Katz DI, Dwyer B, Daneshvar DH, Martin B, Palmisano J, Goldstein LE, Crary JF, Nowinski C, Cantu RC, Kowall NW, Stern RA, Delalle I, McKee AC, Stein TD. Cortical-sparing chronic traumatic encephalopathy (CSCTE): a distinct subtype of CTE. Acta Neuropathol. 2024 Feb 26; 147(1):45.View Related Profiles. PMID: 38407651
     
  4. Agrawal S, Leurgans SE, Barnes LL, Dams-O'Connor K, Mez J, Bennett DA, Schneider JA. Chronic traumatic encephalopathy and aging-related tau astrogliopathy in community-dwelling older persons with and without moderate-to-severe traumatic brain injury. J Neuropathol Exp Neurol. 2024 Feb 21; 83(3):181-193. PMID: 38300796; PMCID: PMC10880068; DOI: 10.1093/jnen/nlae007;
     
  5. Alosco ML, White M, Bell C, Faheem F, Tripodis Y, Yhang E, Baucom Z, Martin B, Palmisano J, Dams-O'Connor K, Crary JF, Goldstein LE, Katz DI, Dwyer B, Daneshvar DH, Nowinski C, Cantu RC, Kowall NW, Stern RA, Alvarez VE, Huber BR, Stein TD, McKee AC, Mez J. Cognitive, functional, and neuropsychiatric correlates of regional tau pathology in autopsy-confirmed chronic traumatic encephalopathy. Mol Neurodegener. 2024 Feb 06; 19(1):10.View Related Profiles. PMID: 38317248; PMCID: PMC10845638; DOI: 10.1186/s13024-023-00697-2;
     
  6. Montoliu-Gaya L, Alosco ML, Yhang E, Tripodis Y, Sconzo D, Ally M, Grötschel L, Ashton NJ, Lantero-Rodriguez J, Sauer M, Gomes B, Nilsson J, Brinkmalm G, Sugarman MA, Aparicio HJ, Martin B, Palmisano JN, Steinberg EG, Simkin I, Turk KW, Budson AE, Au R, Farrer L, Jun GR, Kowall NW, Stern RA, Goldstein LE, Qiu WQ, Mez J, Huber BR, Alvarez VE, McKee AC, Zetterberg H, Gobom J, Stein TD, Blennow K. Optimal blood tau species for the detection of Alzheimer's disease neuropathology: an immunoprecipitation mass spectrometry and autopsy study. Acta Neuropathol. 2023 Dec 30; 147(1):5.View Related Profiles. PMID: 38159140; PMCID: PMC10757700; DOI: 10.1007/s00401-023-02660-3;
     
  7. Su Y, Protas H, Luo J, Chen K, Alosco ML, Adler CH, Balcer LJ, Bernick C, Au R, Banks SJ, Barr WB, Coleman MJ, Dodick DW, Katz DI, Marek KL, McClean MD, McKee AC, Mez J, Daneshvar DH, Palmisano JN, Peskind ER, Turner RW, Wethe JV, Rabinovici G, Johnson K, Tripodis Y, Cummings JL, Shenton ME, Stern RA, Reiman EM. Flortaucipir tau PET findings from former professional and college American football players in the DIAGNOSE CTE research project. Alzheimers Dement. 2024 Mar; 20(3):1827-1838.View Related Profiles. PMID: 38134231; PMCID: PMC10984430; DOI: 10.1002/alz.13602;
     
  8. Ly MT, Tuz-Zahra F, Tripodis Y, Adler CH, Balcer LJ, Bernick C, Zetterberg H, Blennow K, Peskind ER, Au R, Banks SJ, Barr WB, Wethe JV, Bondi MW, Delano-Wood LM, Cantu RC, Coleman MJ, Dodick DW, McClean MD, Mez JB, Palmisano J, Martin B, Hartlage K, Lin AP, Koerte IK, Cummings JL, Reiman EM, Shenton ME, Stern RA, Bouix S, Alosco ML. Association of Vascular Risk Factors and CSF and Imaging Biomarkers With White Matter Hyperintensities in Former American Football Players. Neurology. 2024 Jan 23; 102(2):e208030.View Related Profiles. PMID: 38165330; PMCID: PMC10870736; DOI: 10.1212/WNL.0000000000208030;
     
  9. Crane PK, Groot C, Ossenkoppele R, Mukherjee S, Choi SE, Lee M, Scollard P, Gibbons LE, Sanders RE, Trittschuh E, Saykin AJ, Mez J, Nakano C, Donald CM, Sohi H, Risacher S. Cognitively defined Alzheimer's dementia subgroups have distinct atrophy patterns. Alzheimers Dement. 2024 Mar; 20(3):1739-1752. PMID: 38093529; PMCID: PMC10984445; DOI: 10.1002/alz.13567;
     
  10. Groechel RC, Alosco ML, Dixon D, Tripodis Y, Mez J, Goldstein L, Budson AE, Qiu WQ, Killiany RJ. Associations between white matter integrity of the cingulum bundle, surrounding gray matter regions, and cognition across the dementia continuum. J Comp Neurol. 2023 Dec; 531(18):2162-2171.View Related Profiles. PMID: 38010204; PMCID: PMC10841586; DOI: 10.1002/cne.25564;
     
Showing 10 of 155 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 155 publications over 16 distinct years, with a maximum of 37 publications in 2023

YearPublications
20041
20071
20091
20101
20135
20141
20155
20168
20179
20187
201911
202018
202120
202225
202337
20245


New Boston University study could help diagnose CTE before death

NBC 10 Boston 2/7/2024

BU researchers publish ‘crucial’ study that could help diagnose CTE before death

Boston.com 2/6/2024

BU researchers say they’re closer to diagnosing CTE during life, rather than after death

Boston 25 2/6/2024

Boston University researchers may be closer to identifying CTE in living patients

CBS News 2/6/2024

New Boston University study may help develop way to diagnose CTE in living patients

WCVB-TV 2/6/2024

Researchers get closer to diagnosing CTE in living patients

Futurity 2/6/2024

Researchers Are One Step Closer to Diagnosing CTE during Life, Rather Than after Death

BU Today 2/5/2024

New Research Suggests That Cumulative Force Of Head Blows, Not The Frequency Of Hits, Is A Better Predictor Of CTE

Chip Chick 8/11/2023

Force of hits, not just number, raises CTE risk

Futurity 6/26/2023

Which Football Players Face Highest Odds for Brain Disorder CTE? New Findings May Tell

US News & World Report 6/26/2023

Head Hits, Not Concussions, Tied to CTE

MedPage Today 6/21/2023

The Force of Blows to the Head, Not Just How Many, Raises Likelihood of CTE

BU Today 6/21/2023

For NHL Players, More Fighting on the Ice Is Linked to Shorter Lives

Health Day 5/11/2023

NHL commissioner disputes link between hockey and CTE brain disease

NPR 4/19/2023

Can Football Fans Watch with a Clear Conscience?

Psychology Today 1/6/2023

New research suggests intensity of hits in sports, not years played, may be better predictor of devastating brain damage

Boston Globe 8/3/2022

Genetic Variation May Explain Differences in CTE Risk After Repetitive Head Impact

Medscape 7/11/2022

Genetic variant may increase risk for CTE severity among older individuals with repetitive head impacts

Medical Xpress 6/27/2022

Boston University CTE study: Genes may play major role in CTE severity

Boston Herald 6/27/2022

Former football pros die at a faster rate than baseball veterans—and the reasons are surprising

Science 6/24/2022

More Years Playing Hockey, Higher Odds for CTE Linked to Head Injury

Health Day 3/3/2022

More Years of Ice Hockey Play Tied to Higher CTE Risk

Medscape 3/3/2022

Boston University scientists making progress in CTE research

WHDH-TV 12/13/2021

Boston University scientists getting closer to diagnosing CTE in living people using MRI

Boston Herald 12/11/2021

MRI Might Spot Concussion-Linked CTE in Living Patient

Health Day 12/8/2021

MRI Might Spot Concussion-Linked CTE in Living Patients

US News & World Report 12/8/2021

BU Researchers: CTE Study Offers Potential Path For Diagnosing The Brain Disease Before Death

WBUR 4/7/2021

Each Year You Play Football Increases Your Chances of Developing CTE by 30 Percent

League of Fans 10/29/2020

Soccer Heading Has Greater Impact on Memory in ApoE4 Carriers

Alzforum 1/31/2020

Soccer Headers Might Be More Risky for APOE4 Genotype Carriers

Medscape 1/30/2020

Pointed ‘Tackle Can Wait’ TV ad hits amid sobering new CTE study’s stats

Sporting News 10/14/2019

Every 2.6 Years of Playing American Football Doubles Risk of Devastating Brain Disease

ZME Science 10/9/2019

Scary: Study Finds Every Year of Tackle Football Raises Chances of CTE 30%

The Daily Wire 10/8/2019

NFL stars’ risk of developing the degenerative brain disease CTE soars by a THIRD every year they play, study finds

Daily Mail 10/8/2019

CTE Risk Goes Up 30% For Each Year Of Playing Football

Futurity 10/8/2019

BU Research Finds Link Between Playing Football and CTE

WHDH 10/8/2019

CTE Risk in Football Players Doubles Every Five Years, New Study Finds

Boston Magazine 10/7/2019

CTE Risk More Than Doubles after Just Three Years of Playing Football

BU Today 10/7/2019

CTE Risk, Severity Increases With Years Playing Football, Study Shows

Boston Herald 10/7/2019

College Football Season Is Here. Will Universities Continue To Ignore The Risk Of Brain Damage?

Forbes 9/2/2019

New Jersey Unveils New Limits on High School Football Practices

The New York Times 2/13/2019

Cannabis Studied to Treat Conditions from Football-Related Brain Trauma

WeedMaps 2/4/2019

Why We Still Don’t Know How Many NFL Players Have CTE

Five Thirty Eight 12/17/2018

What's the Risk of Chronic Traumatic Encephalopathy for NFL Players?

Inside Science 11/29/2018

Some People May Have Increased CTE Risk Because Of Their Genes

Inquisitr 11/4/2018

Why Some People’s CTE Symptoms Are More Severe Than Others

BU Today 11/3/2018

Why do some people get CTE? It may be in their genes

CNN Todau 11/3/2018

Why Don't All Football Players Develop CTE? It May Be Genetics

WBGH 11/3/2018

MED Researchers: Youth Football Linked to Earlier Brain Problems

BU Today 4/30/2018

2015 Alzheimer’s Association New Investigator Award
2014 Junior Faculty Spivack Neuroscience Scholar
2013 BU ADC Pilot Grant
2011 NIH Clinical Research Loan Repayment Program recipient
2002 National Student Research Forum grant
2002 Maryland House of Delegates Graduate Scholarship recipient
Contact for Mentoring:

72 E. Concord St Robinson (B)
Boston MA 02118
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