Boston University Alzheimer's Disease Research Center
08/15/2021 - 06/30/2026 (Key Person)
PI: Ann C. McKee, MD
NIH/National Institute on Aging
5P30AG072978-03

The A45 Study: Combination anti-amyloid therapy for preclinical Alzheimer's disease
09/30/2019 - 05/31/2024 (Subcontract PI)
University of Southern California NIH NIA
1R01AG061848-01

AHEAD Plasma Extension (APEX)
05/01/2023 - 04/30/2024 (Subcontract PI)
University of Southern California NIH NIA
5R01AG053798-05

Protocol number BAN2401-G000-303: AHEAD 3-45 Study: A Placebo-Controlled, Double-Blind, Parallel-Treatment Arm, 216 Week Study to Evaluate Efficacy and Safety of Treatment With BAN2401 in Subject
01/01/2020 - 12/31/2023 (Subcontract PI)
University of Southern California Eisai, Inc


Leveraging Existing Aging Research Networks to investigate TBI and AD/ADRD risk (LEARN TBI & AD)
03/15/2019 - 11/30/2023 (Multi-PI)
PI: Jesse B. Mez, MD
Icahn School of Medicine at Mount Sinai NIH NIA
5R01AG061028-05

Alzheimer's Disease Sequencing Project Phenotype Harmonization Consortium
09/30/2021 - 08/31/2023 (Subcontract PI)
Vanderbilt University Medical Center NIH NIA
5U24AG074855-02

Leveraging the Framingham Study to Investigate Relationships between Traumatic Brain Injury, Military Service, Alzheimer's Disease and Related Dementias
09/01/2018 - 08/31/2023 (PI)
Department of Defense/Army Medical Research Acquisition Activity


The A3 Study: Ante-Amyloid prevention of Alzheimer's disease
06/01/2019 - 04/30/2023 (Subcontract PI)
University of Southern California NIH NIA
5R01AG061848-03

ADNI Psychometrics
12/01/2017 - 03/31/2023 (Subcontract PI)
University of Washington NIH NIA
5R01AG029672-10

Genetic Architecture of Memory and Executive Functioning in Alzheimer's Disease
09/01/2014 - 05/31/2019 (Co-Investigator)
University of Washington NIH NIA
5R01AG042437-04

Showing 10 of 13 results. Show All Results

1. Culhane JE, Jackson C, Tripodis Y, Nowinski C, Dams-O'Connor K, Pettway E, Uretsky M, Abdolmohammadi B, Nair E, Martin B, Palmisano J, Katz DI, Dwyer B, Daneshvar DH, Goldstein LE, Kowall NW, Cantu RC, Stern RA, Huber B, Crary J, Mez J, Stein TD, McKee AC, Alosco ML. Lack of association of informant-reported traumatic brain injury and chronic traumatic encephalopathy. J Neurotrauma. 2024 Mar 06.View Related Profiles.

   McKee, Ann
   Huber, Bertrand
   Dwyer, Brigid
   Nowinski, Christopher
   Daneshvar, Daniel
   Katz, Douglas
   Mez, Jesse
   Goldstein, Lee
   Alosco, Michael
   Kowall, Neil
   Stern, Robert
   Stein, Thor
   Tripodis, Yorghos
   

   PMID: 38445389
2. Banks SJ, Yhang E, Tripodis Y, Su Y, Protas H, Adler CH, Balcer LJ, Bernick C, Mez JB, Palmisano J, Barr WB, Wethe JV, Dodick DW, Mcclean MD, Martin B, Hartlage K, Turner A, Turner RW, Malhotra A, Colman M, Pasternak O, Lin AP, Koerte IK, Bouix S, Cummings JL, Shenton ME, Reiman EM, Stern RA, Alosco ML. Clinical Outcomes and Tau Pathology in Retired Football Players: Associations With Diagnosed and Witnessed Sleep Apnea. Neurol Clin Pract. 2024 Apr; 14(2):e200263.View Related Profiles.

   Mez, Jesse
   Alosco, Michael
   McClean, Michael
   Stern, Robert
   Tripodis, Yorghos
   

   PMID: 38425491; PMCID: PMC10900387; DOI: 10.1212/CPJ.0000000000200263;
3. Alexander A, Alvarez VE, Huber BR, Alosco ML, Mez J, Tripodis Y, Nicks R, Katz DI, Dwyer B, Daneshvar DH, Martin B, Palmisano J, Goldstein LE, Crary JF, Nowinski C, Cantu RC, Kowall NW, Stern RA, Delalle I, McKee AC, Stein TD. Cortical-sparing chronic traumatic encephalopathy (CSCTE): a distinct subtype of CTE. Acta Neuropathol. 2024 Feb 26; 147(1):45.View Related Profiles.

   McKee, Ann
   Huber, Bertrand
   Dwyer, Brigid
   Nowinski, Christopher
   Daneshvar, Daniel
   Katz, Douglas
   Delalle, Ivana
   Mez, Jesse
   Goldstein, Lee
   Alosco, Michael
   Kowall, Neil
   Stern, Robert
   Stein, Thor
   Alvarez, Victor
   Tripodis, Yorghos
   

   PMID: 38407651
4. Agrawal S, Leurgans SE, Barnes LL, Dams-O'Connor K, Mez J, Bennett DA, Schneider JA. Chronic traumatic encephalopathy and aging-related tau astrogliopathy in community-dwelling older persons with and without moderate-to-severe traumatic brain injury. J Neuropathol Exp Neurol. 2024 Feb 21; 83(3):181-193. PMID: 38300796; PMCID: PMC10880068; DOI: 10.1093/jnen/nlae007;
5. Alosco ML, White M, Bell C, Faheem F, Tripodis Y, Yhang E, Baucom Z, Martin B, Palmisano J, Dams-O'Connor K, Crary JF, Goldstein LE, Katz DI, Dwyer B, Daneshvar DH, Nowinski C, Cantu RC, Kowall NW, Stern RA, Alvarez VE, Huber BR, Stein TD, McKee AC, Mez J. Cognitive, functional, and neuropsychiatric correlates of regional tau pathology in autopsy-confirmed chronic traumatic encephalopathy. Mol Neurodegener. 2024 Feb 06; 19(1):10.View Related Profiles.

   McKee, Ann
   Huber, Bertrand
   Dwyer, Brigid
   Nowinski, Christopher
   Daneshvar, Daniel
   Katz, Douglas
   Mez, Jesse
   Goldstein, Lee
   Alosco, Michael
   Kowall, Neil
   Stern, Robert
   Stein, Thor
   Alvarez, Victor
   Tripodis, Yorghos
   

   PMID: 38317248; PMCID: PMC10845638; DOI: 10.1186/s13024-023-00697-2;
6. Montoliu-Gaya L, Alosco ML, Yhang E, Tripodis Y, Sconzo D, Ally M, Grötschel L, Ashton NJ, Lantero-Rodriguez J, Sauer M, Gomes B, Nilsson J, Brinkmalm G, Sugarman MA, Aparicio HJ, Martin B, Palmisano JN, Steinberg EG, Simkin I, Turk KW, Budson AE, Au R, Farrer L, Jun GR, Kowall NW, Stern RA, Goldstein LE, Qiu WQ, Mez J, Huber BR, Alvarez VE, McKee AC, Zetterberg H, Gobom J, Stein TD, Blennow K. Optimal blood tau species for the detection of Alzheimer's disease neuropathology: an immunoprecipitation mass spectrometry and autopsy study. Acta Neuropathol. 2023 Dec 30; 147(1):5.View Related Profiles.

   Budson, Andrew
   McKee, Ann
   Huber, Bertrand
   Sconzo, Daniel
   Steinberg, Eric
   Jun, Gyungah
   Aparicio, Hugo
   Mez, Jesse
   Turk, Katherine
   Goldstein, Lee
   Farrer, Lindsay
   Alosco, Michael
   Kowall, Neil
   Au, Rhoda
   Stern, Robert
   Stein, Thor
   Alvarez, Victor
   Tripodis, Yorghos
   

   PMID: 38159140; PMCID: PMC10757700; DOI: 10.1007/s00401-023-02660-3;
7. Su Y, Protas H, Luo J, Chen K, Alosco ML, Adler CH, Balcer LJ, Bernick C, Au R, Banks SJ, Barr WB, Coleman MJ, Dodick DW, Katz DI, Marek KL, McClean MD, McKee AC, Mez J, Daneshvar DH, Palmisano JN, Peskind ER, Turner RW, Wethe JV, Rabinovici G, Johnson K, Tripodis Y, Cummings JL, Shenton ME, Stern RA, Reiman EM. Flortaucipir tau PET findings from former professional and college American football players in the DIAGNOSE CTE research project. Alzheimers Dement. 2024 Mar; 20(3):1827-1838.View Related Profiles.

   McKee, Ann
   Daneshvar, Daniel
   Katz, Douglas
   Mez, Jesse
   Alosco, Michael
   McClean, Michael
   Au, Rhoda
   Stern, Robert
   Tripodis, Yorghos
   

   PMID: 38134231
8. Ly MT, Tuz-Zahra F, Tripodis Y, Adler CH, Balcer LJ, Bernick C, Zetterberg H, Blennow K, Peskind ER, Au R, Banks SJ, Barr WB, Wethe JV, Bondi MW, Delano-Wood LM, Cantu RC, Coleman MJ, Dodick DW, McClean MD, Mez JB, Palmisano J, Martin B, Hartlage K, Lin AP, Koerte IK, Cummings JL, Reiman EM, Shenton ME, Stern RA, Bouix S, Alosco ML. Association of Vascular Risk Factors and CSF and Imaging Biomarkers With White Matter Hyperintensities in Former American Football Players. Neurology. 2024 Jan 23; 102(2):e208030.View Related Profiles.

   Mez, Jesse
   Alosco, Michael
   McClean, Michael
   Ly, Monica
   Au, Rhoda
   Stern, Robert
   Tripodis, Yorghos
   

   PMID: 38165330; PMCID: PMC10870736; DOI: 10.1212/WNL.0000000000208030;
9. Crane PK, Groot C, Ossenkoppele R, Mukherjee S, Choi SE, Lee M, Scollard P, Gibbons LE, Sanders RE, Trittschuh E, Saykin AJ, Mez J, Nakano C, Donald CM, Sohi H, Risacher S. Cognitively defined Alzheimer's dementia subgroups have distinct atrophy patterns. Alzheimers Dement. 2024 Mar; 20(3):1739-1752. PMID: 38093529
10. Groechel RC, Alosco ML, Dixon D, Tripodis Y, Mez J, Goldstein L, Budson AE, Qiu WQ, Killiany RJ. Associations between white matter integrity of the cingulum bundle, surrounding gray matter regions, and cognition across the dementia continuum. J Comp Neurol. 2023 Dec; 531(18):2162-2171.View Related Profiles.

    Budson, Andrew
    Mez, Jesse
    Alosco, Michael
    Tripodis, Yorghos
    

    PMID: 38010204; PMCID: PMC10841586; DOI: 10.1002/cne.25564;

Showing 10 of 155 results. Show More

New Boston University study could help diagnose CTE before death

BU researchers publish ‘crucial’ study that could help diagnose CTE before death

BU researchers say they’re closer to diagnosing CTE during life, rather than after death

Boston University researchers may be closer to identifying CTE in living patients

New Boston University study may help develop way to diagnose CTE in living patients

Researchers get closer to diagnosing CTE in living patients

Researchers Are One Step Closer to Diagnosing CTE during Life, Rather Than after Death

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New Research Suggests That Cumulative Force Of Head Blows, Not The Frequency Of Hits, Is A Better Predictor Of CTE

Force of hits, not just number, raises CTE risk

Which Football Players Face Highest Odds for Brain Disorder CTE? New Findings May Tell

Head Hits, Not Concussions, Tied to CTE

The Force of Blows to the Head, Not Just How Many, Raises Likelihood of CTE

For NHL Players, More Fighting on the Ice Is Linked to Shorter Lives

NHL commissioner disputes link between hockey and CTE brain disease

Can Football Fans Watch with a Clear Conscience?

New research suggests intensity of hits in sports, not years played, may be better predictor of devastating brain damage

Genetic Variation May Explain Differences in CTE Risk After Repetitive Head Impact

Genetic variant may increase risk for CTE severity among older individuals with repetitive head impacts

Boston University CTE study: Genes may play major role in CTE severity

Former football pros die at a faster rate than baseball veterans—and the reasons are surprising

More Years Playing Hockey, Higher Odds for CTE Linked to Head Injury

More Years of Ice Hockey Play Tied to Higher CTE Risk

Boston University scientists making progress in CTE research

BU scientists getting closer to diagnosing CTE in Living people using MRI

Boston University scientists getting closer to diagnosing CTE in living people using MRI

MRI Might Spot Concussion-Linked CTE in Living Patients

MRI Might Spot Concussion-Linked CTE in Living Patient

BU Researchers: CTE Study Offers Potential Path For Diagnosing The Brain Disease Before Death

Each Year You Play Football Increases Your Chances of Developing CTE by 30 Percent

Soccer Heading Has Greater Impact on Memory in ApoE4 Carriers

Soccer Headers Might Be More Risky for APOE4 Genotype Carriers

Pointed ‘Tackle Can Wait’ TV ad hits amid sobering new CTE study’s stats

Every 2.6 Years of Playing American Football Doubles Risk of Devastating Brain Disease

NFL Stars' Risk of Developing the Degenerative Brain Disease CTE Soars by a THIRD Every Year They Play, Study Finds

Scary: Study Finds Every Year of Tackle Football Raises Chances of CTE 30%

NFL stars’ risk of developing the degenerative brain disease CTE soars by a THIRD every year they play, study finds

CTE Risk Goes Up 30% For Each Year Of Playing Football

BU Research Finds Link Between Playing Football and CTE

CTE Risk in Football Players Doubles Every Five Years, New Study Finds

CTE Risk More Than Doubles after Just Three Years of Playing Football

CTE Risk, Severity Increases With Years Playing Football, Study Shows

College Football Season Is Here. Will Universities Continue To Ignore The Risk Of Brain Damage?

New Jersey Unveils New Limits on High School Football Practices

Cannabis Studied to Treat Conditions from Football-Related Brain Trauma

Why We Still Don’t Know How Many NFL Players Have CTE

What's the Risk of Chronic Traumatic Encephalopathy for NFL Players?

Some People May Have Increased CTE Risk Because Of Their Genes

Why Some People’s CTE Symptoms Are More Severe Than Others

Why do some people get CTE? It may be in their genes

Why Don't All Football Players Develop CTE? It May Be Genetics

MED Researchers: Youth Football Linked to Earlier Brain Problems