Jesse B. Mez, MD
Assistant Professor
Boston University School of Medicine
Dept of Neurology

MD, University of Maryland School of Medicine
MS, Columbia University School of Public Health



Dr. Mez completed his undergraduate studies at Cornell University and earned his medical degree from the University of Maryland School of Medicine. He completed residency training in Neurology at Massachusetts General and Brigham and Women’s Hospitals. He completed a clinical fellowship in Aging and Dementia and a research fellowship in Neuroepidemiology at Columbia University. During fellowship training, he also earned a Masters in Biostatistics with a focus on Statistical Genetics from the Mailman School of Public Health at Columbia. In 2013, he became an Assistant Professor of Neurology at Boston University School of Medicine.


Research Interests
Dr. Mez’s research focuses on the application of statistical genetics and genetic epidemiology to various forms of dementia. He is particularly interested in the role of genetic and non-genetic factors in atypical clinical presentations of Alzheimer’s disease. He also is interested in how the interaction of genetic risk factors and trauma influence dementia risk, particularly chronic traumatic encephalopathy. He leads the clinical arm of Ann McKee’s UNITE study. He is mentored by Dr. Lindsay Farrer, head of the Biomedical Genetics Division in the Department of Medicine and works closely with division members.

ADC Role
Dr. Mez is Associate Director of the ADC’s Clinical Core. He helps make clinical consensus diagnoses for ADC participants. He also provides clinical evaluations for ADC clinical trials.

Awards and Memberships
Dr. Mez is a 2015 Spivack Neuroscience Scholar. He is a recipient of a K23 Mentored Patient-Oriented Research Career Development Award from the National Institute on Aging. He received the 2013-2014 BU ADC Pilot Grant. He is a recipient of the NIH Loan Repayment Program. He is a member of the American Academy of Neurology, the American Society of Human Genetics, the International Society to Advance Alzheimer’s Research and Treatment and the Society for Behavioral and Cognitive Neurology


ADNI Psychometrics
12/01/2017 - 03/31/2022 (PI)
University of Washington NIH NIA
5R01AG029672-07

Genetic Architecture of Memory and Executive Functioning in Alzheimer's Disease
09/01/2014 - 05/31/2019 (Co-PI)
PI: Richard Sherva, PhD
University of Washington NIH NIA
5R01AG042437-04

Genetic and Neuropsychological Heterogeneity in Alzheimer's Disease
08/15/2014 - 05/31/2019 (PI)
NIH/National Institute on Aging
5K23AG046377-05

Exploring MAPT and tau-related genes in chonic traumatic encephalopathy
10/01/2015 - 09/30/2017 (PI)
Alzheimer's Association




Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Adams JW, Alvarez VE, Mez J, Huber BR, Tripodis Y, Xia W, Meng G, Kubilus CA, Cormier K, Kiernan PT, Daneshvar DH, Chua AS, Svirsky S, Nicks R, Abdolmohammadi B, Evers L, Solomon TM, Cherry JD, Aytan N, Mahar I, Devine S, Auerbach S, Alosco ML, Nowinski CJ, Kowall NW, Goldstein LE, Dwyer B, Katz DI, Cantu RC, Stern RA, Au R, McKee AC, Stein TD. Lewy Body Pathology and Chronic Traumatic Encephalopathy Associated With Contact Sports. J Neuropathol Exp Neurol. 2018 Jul 25.View Related Profiles. PMID: 30053297.
     
  2. Alosco ML, Tripodis Y, Fritts NG, Heslegrave A, Baugh CM, Conneely S, Mariani M, Martin BM, Frank S, Mez J, Stein TD, Cantu RC, McKee AC, Shaw LM, Trojanowski JQ, Blennow K, Zetterberg H, Stern RA. Cerebrospinal fluid tau, Aß, and sTREM2 in Former National Football League Players: Modeling the relationship between repetitive head impacts, microglial activation, and neurodegeneration. Alzheimers Dement. 2018 Jul 23.View Related Profiles. PMID: 30049650.
     
  3. Alosco ML, Mez J, Tripodis Y, Kiernan PT, Abdolmohammadi B, Murphy L, Kowall NW, Stein TD, Huber BR, Goldstein LE, Cantu RC, Katz DI, Chaisson CE, Martin B, Solomon TM, McClean MD, Daneshvar DH, Nowinski CJ, Stern RA, McKee AC. Age of first exposure to tackle football and chronic traumatic encephalopathy. Ann Neurol. 2018 May; 83(5):886-901.View Related Profiles. PMID: 29710395.
     
  4. Chung J, Zhang X, Allen M, Wang X, Ma Y, Beecham G, Montine TJ, Younkin SG, Dickson DW, Golde TE, Price ND, Ertekin-Taner N, Lunetta KL, Mez J, Mayeux R, Haines JL, Pericak-Vance MA, Schellenberg G, Jun GR, Farrer LA. Genome-wide pleiotropy analysis of neuropathological traits related to Alzheimer's disease. Alzheimers Res Ther. 2018 Feb 20; 10(1):22.View Related Profiles. PMID: 29458411.
     
  5. Alosco ML, Sugarman MA, Besser LM, Tripodis Y, Martin B, Palmisano JN, Kowall NW, Au R, Mez J, DeCarli C, Stein TD, McKee AC, Killiany RJ, Stern RA. A Clinicopathological Investigation of White Matter Hyperintensities and Alzheimer's Disease Neuropathology. J Alzheimers Dis. 2018; 63(4):1347-1360.View Related Profiles. PMID: 29843242; DOI: 10.3233/JAD-180017;.
     
  6. Chung J, Wang X, Maruyama T, Ma Y, Zhang X, Mez J, Sherva R, Takeyama H, Lunetta KL, Farrer LA, Jun GR. Genome-wide association study of Alzheimer's disease endophenotypes at prediagnosis stages. Alzheimers Dement. 2018 May; 14(5):623-633.View Related Profiles. PMID: 29274321.
     
  7. McKee AC, Mez J, Abdolmohammadi B. Chronic Traumatic Encephalopathy in Football Players-Reply. JAMA. 2017 12 19; 318(23):2353.View Related Profiles. PMID: 29260223.
     
  8. Cherry JD, Stein TD, Tripodis Y, Alvarez VE, Huber BR, Au R, Kiernan PT, Daneshvar DH, Mez J, Solomon TM, Alosco ML, McKee AC. CCL11 is increased in the CNS in chronic traumatic encephalopathy but not in Alzheimer's disease. PLoS One. 2017; 12(9):e0185541.View Related Profiles. PMID: 28950005; DOI: 10.1371/journal.pone.0185541;.
     
  9. Alosco ML, Kasimis AB, Stamm JM, Chua AS, Baugh CM, Daneshvar DH, Robbins CA, Mariani M, Hayden J, Conneely S, Au R, Torres A, McClean MD, McKee AC, Cantu RC, Mez J, Nowinski CJ, Martin BM, Chaisson CE, Tripodis Y, Stern RA. Age of first exposure to American football and long-term neuropsychiatric and cognitive outcomes. Transl Psychiatry. 2017 Sep 19; 7(9):e1236.View Related Profiles. PMID: 28926003; DOI: 10.1038/tp.2017.197;.
     
  10. Mez J, Marden JR, Mukherjee S, Walter S, Gibbons LE, Gross AL, Zahodne LB, Gilsanz P, Brewster P, Nho K, Crane PK, Larson EB, Glymour MM. Alzheimer's disease genetic risk variants beyond APOE e4 predict mortality. Alzheimers Dement (Amst). 2017; 8:188-195. PMID: 28983503.
     
Showing 10 of 37 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 37 publications over 10 distinct years, with a maximum of 9 publications in 2017

YearPublications
20041
20071
20091
20101
20135
20141
20155
20168
20179
20185
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Boston MA 02118
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