Jesse B. Mez, MD
Associate Professor
Boston University School of Medicine
Dept of Neurology

MD, University of Maryland School of Medicine
MS, Columbia University School of Public Health




Dr. Mez completed his undergraduate studies at Cornell University and earned his medical degree from the University of Maryland School of Medicine. He completed residency training in Neurology at Massachusetts General and Brigham and Women’s Hospitals. He completed a clinical fellowship in Aging and Dementia and a research fellowship in Neuroepidemiology at Columbia University. During fellowship training, he also earned a Masters in Biostatistics with a focus on Statistical Genetics from the Mailman School of Public Health at Columbia. In 2013, he became an Assistant Professor of Neurology at Boston University (BU) School of Medicine. In 2014, he became Associate Director of the BU Alzheimer's Disease Center (ADC) Clinical Core.

Investigator
Framingham Heart Study


Member
Boston University
Evans Center for Interdisciplinary Biomedical Research




ADNI Psychometrics
12/01/2017 - 03/31/2023 (Subcontract PI)
University of Washington NIH NIA
5R01AG029672-10

Leveraging Existing Aging Research Networks to investigate TBI and AD/ADRD risk (LEARN TBI & AD)
03/15/2019 - 11/30/2022 (Subcontract PI)
Icahn School of Medicine at Mount Sinai NIH NIA
5R01AG061028-04

Alzheimer's Disease Sequencing Project Phenotype Harmonization Consortium
09/30/2021 - 08/31/2022 (Subcontract PI)
Vanderbilt University Medical Center NIH NIA
1U24AG074855-01

Leveraging the Framingham Study to Investigate Relationships between Traumatic Brain Injury, Military Service, Alzheimer's Disease and Related Dementias
09/01/2018 - 08/31/2022 (PI)
Department of Defense/Army Medical Research Acquisition Activity


Genetic Architecture of Memory and Executive Functioning in Alzheimer's Disease
09/01/2014 - 05/31/2019 (Co-Investigator)
University of Washington NIH NIA
5R01AG042437-04

Genetic and Neuropsychological Heterogeneity in Alzheimer's Disease
08/15/2014 - 05/31/2019 (PI)
NIH/National Institute on Aging
5K23AG046377-05

Exploring MAPT and tau-related genes in chonic traumatic encephalopathy
10/01/2015 - 09/30/2017 (PI)
Alzheimer's Association


Personnel agreement for research services of Jesse Mez
07/01/2014 - 06/30/2015 (Key Person)
PI: Andrew E. Budson, MD
VA Boston Healthcare System




Title


Yr Title Project-Sub Proj Pubs
2022 Core B: Clinical Core 5P30AG072978-02-9742
2022 Clinicopathological Correlation in Chronic Traumatic Encephalopathy (CTE) and Chronic Traumatic Brain Injury (cTBI) 5U54NS115266-04-6601
2022 Leveraging Existing Aging Research Networks to investigate TBI and AD/ADRD risk (LEARN TBI & AD) 5R01AG061028-04
2021 Core B: Clinical Core 1P30AG072978-01-9742
2021 Clinicopathological Correlation in Chronic Traumatic Encephalopathy (CTE) and Chronic Traumatic Brain Injury (cTBI) 5U54NS115266-03-6601
2021 Leveraging Existing Aging Research Networks to investigate TBI and AD/ADRD risk (LEARN TBI & AD) 5R01AG061028-03 2
2020 Clinicopathological Correlation in Chronic Traumatic Encephalopathy (CTE) and Chronic Traumatic Brain Injury (cTBI) 5U54NS115266-02-6601
2020 Leveraging Existing Aging Research Networks to investigate TBI and AD/ADRD risk (LEARN TBI & AD) 5R01AG061028-02 2
2019 Core B: Clinical Core 5P30AG013846-23-6895 874
2019 Leveraging Existing Aging Research Networks to investigate TBI and AD/ADRD risk (LEARN TBI & AD) 1R01AG061028-01 2
Showing 10 of 16 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Atherton K, Han X, Chung J, Cherry JD, Baucom Z, Saltiel N, Nair E, Abdolmohammadi B, Uretsky M, Khan MM, Shea C, Durape S, Martin BM, Palmisano JN, Farrell K, Nowinski CJ, Alvarez VE, Dwyer B, Daneshvar DH, Katz DI, Goldstein LE, Cantu RC, Kowall NW, Alosco ML, Huber BR, Tripodis Y, Crary JF, Farrer L, Stern RA, Stein TD, McKee AC, Mez J. Association of APOE Genotypes and Chronic Traumatic Encephalopathy. JAMA Neurol. 2022 Aug 01; 79(8):787-796.View Related Profiles. PMID: 35759276; PMCID: PMC9237800; DOI: 10.1001/jamaneurol.2022.1634;
     
  2. Eissman JM, Dumitrescu L, Mahoney ER, Smith AN, Mukherjee S, Lee ML, Scollard P, Choi SE, Bush WS, Engelman CD, Lu Q, Fardo DW, Trittschuh EH, Mez J, Kaczorowski CC, Hernandez Saucedo H, Widaman KF, Buckley RF, Properzi MJ, Mormino EC, Yang HS, Harrison TM, Hedden T, Nho K, Andrews SJ, Tommet D, Hadad N, Sanders RE, Ruderfer DM, Gifford KA, Zhong X, Raghavan NS, Vardarajan BN, Pericak-Vance MA, Farrer LA, Wang LS, Cruchaga C, Schellenberg GD, Cox NJ, Haines JL, Keene CD, Saykin AJ, Larson EB, Sperling RA, Mayeux R, Cuccaro ML, Bennett DA, Schneider JA, Crane PK, Jefferson AL, Hohman TJ. Sex differences in the genetic architecture of cognitive resilience to Alzheimer's disease. Brain. 2022 Jul 29; 145(7):2541-2554.View Related Profiles. PMID: 35552371; PMCID: PMC9337804; DOI: 10.1093/brain/awac177;
     
  3. LeClair J, Weuve J, Fox MP, Mez J, Alosco ML, Nowinski C, McKee A, Tripodis Y. Relationship Between Level of American Football Playing and Diagnosis of Chronic Traumatic Encephalopathy in a Selection Bias Analysis. Am J Epidemiol. 2022 Jul 23; 191(8):1429-1443.View Related Profiles. PMID: 35434739; DOI: 10.1093/aje/kwac075;
     
  4. Chung J, Das A, Sun X, Sobreira DR, Leung YY, Igartua C, Mozaffari S, Chou YF, Thiagalingam S, Mez J, Zhang X, Jun GR, Stein TD, Kunkle BW, Martin ER, Pericak-Vance MA, Mayeux R, Haines JL, Schellenberg GD, Nobrega MA, Lunetta KL, Pinto JM, Wang LS, Ober C, Farrer LA. Genome-wide association and multi-omics studies identify MGMT as a novel risk gene for Alzheimer's disease among women. Alzheimers Dement. 2022 Jun 30.View Related Profiles. PMID: 35770850
     
  5. Qiu S, Miller MI, Joshi PS, Lee JC, Xue C, Ni Y, Wang Y, De Anda-Duran I, Hwang PH, Cramer JA, Dwyer BC, Hao H, Kaku MC, Kedar S, Lee PH, Mian AZ, Murman DL, O'Shea S, Paul AB, Saint-Hilaire MH, Alton Sartor E, Saxena AR, Shih LC, Small JE, Smith MJ, Swaminathan A, Takahashi CE, Taraschenko O, You H, Yuan J, Zhou Y, Zhu S, Alosco ML, Mez J, Stein TD, Poston KL, Au R, Kolachalama VB. Multimodal deep learning for Alzheimer's disease dementia assessment. Nat Commun. 2022 Jun 20; 13(1):3404.View Related Profiles. PMID: 35725739; PMCID: PMC9209452; DOI: 10.1038/s41467-022-31037-5;
     
  6. Alvia M, Aytan N, Spencer KR, Foster ZW, Rauf NA, Guilderson L, Robey I, Averill JG, Walker SE, Alvarez VE, Huber BR, Mathais R, Cormier KA, Nicks R, Pothast M, Labadorf A, Agus F, Alosco ML, Mez J, Kowall NW, McKee AC, Brady CB, Stein TD. MicroRNA Alterations in Chronic Traumatic Encephalopathy and Amyotrophic Lateral Sclerosis. Front Neurosci. 2022; 16:855096.View Related Profiles. PMID: 35663558; PMCID: PMC9160996; DOI: 10.3389/fnins.2022.855096;
     
  7. You Y, Hersh SW, Aslebagh R, Shaffer SA, Ikezu S, Mez J, Lunetta KL, Logue MW, Farrer LA, Ikezu T. Alzheimer's disease associated AKAP9 I2558M mutation alters posttranslational modification and interactome of tau and cellular functions in CRISPR-edited human neuronal cells. Aging Cell. 2022 Jun; 21(6):e13617.View Related Profiles. PMID: 35567427; PMCID: PMC9197405; DOI: 10.1111/acel.13617;
     
  8. Morrison MS, Aparicio HJ, Blennow K, Zetterberg H, Ashton NJ, Karikari TK, Tripodis Y, Martin B, Palmisano JN, Sugarman MA, Frank B, Steinberg EG, Turk KW, Budson AE, Au R, Goldstein LE, Jun GR, Kowall NW, Killiany R, Qiu WQ, Stern RA, Mez J, McKee AC, Stein TD, Alosco ML. Antemortem plasma phosphorylated tau (181) predicts Alzheimer's disease neuropathology and regional tau at autopsy. Brain. 2022 May 13.View Related Profiles. PMID: 35554506; DOI: 10.1093/brain/awac175;
     
  9. Frank B, Ally M, Tripodis Y, Puzo C, Labriolo C, Hurley L, Martin B, Palmisano J, Chan L, Steinberg E, Turk K, Budson A, O'Connor M, Au R, Qiu WQ, Goldstein L, Kukull W, Kowall N, Killiany R, Stern R, Stein T, McKee A, Mez J, Alosco M. Trajectories of Cognitive Decline in Brain Donors With Autopsy-Confirmed Alzheimer Disease and Cerebrovascular Disease. Neurology. 2022 Jun 14; 98(24):e2454-e2464.View Related Profiles. PMID: 35444054; PMCID: PMC9231841; DOI: 10.1212/WNL.0000000000200304;
     
  10. Yuan J, Au R, Karjadi C, Ang TF, Devine S, Auerbach S, DeCarli C, Libon DJ, Mez J, Lin H. Associations Between the Digital Clock Drawing Test and Brain Volume: Large Community-Based Prospective Cohort (Framingham Heart Study). J Med Internet Res. 2022 Apr 15; 24(4):e34513.View Related Profiles. PMID: 35436225; PMCID: PMC9055470; DOI: 10.2196/34513;
     
Showing 10 of 105 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 105 publications over 14 distinct years, with a maximum of 20 publications in 2021

YearPublications
20041
20071
20091
20101
20135
20141
20155
20168
20179
20187
201911
202018
202120
202217


Recent (within 3 months)

New research suggests intensity of hits in sports, not years played, may be better predictor of devastating brain damage

Boston Globe 8/3/2022

Genetic Variation May Explain Differences in CTE Risk After Repetitive Head Impact

Medscape 7/11/2022

Older

Genetic variant may increase risk for CTE severity among older individuals with repetitive head impacts

Medical Xpress 6/27/2022

Boston University CTE study: Genes may play major role in CTE severity

Boston Herald 6/27/2022

Former football pros die at a faster rate than baseball veterans—and the reasons are surprising

Science 6/24/2022

More Years Playing Hockey, Higher Odds for CTE Linked to Head Injury

Health Day 3/3/2022

More Years of Ice Hockey Play Tied to Higher CTE Risk

Medscape 3/3/2022

Boston University scientists making progress in CTE research

WHDH-TV 12/13/2021

BU scientists getting closer to diagnosing CTE in Living people using MRI

Boston Herald 12/12/2021

Boston University scientists getting closer to diagnosing CTE in living people using MRI

Boston Herald 12/11/2021

MRI Might Spot Concussion-Linked CTE in Living Patients

US News & World Report 12/8/2021

MRI Might Spot Concussion-Linked CTE in Living Patient

Health Day 12/8/2021

BU Researchers: CTE Study Offers Potential Path For Diagnosing The Brain Disease Before Death

WBUR 4/7/2021

Each Year You Play Football Increases Your Chances of Developing CTE by 30 Percent

League of Fans 10/29/2020

Soccer Heading Has Greater Impact on Memory in ApoE4 Carriers

Alzforum 1/31/2020

Soccer Headers Might Be More Risky for APOE4 Genotype Carriers

Medscape 1/30/2020

Pointed ‘Tackle Can Wait’ TV ad hits amid sobering new CTE study’s stats

Sporting News 10/14/2019

Every 2.6 Years of Playing American Football Doubles Risk of Devastating Brain Disease

ZME Science 10/9/2019

NFL Stars' Risk of Developing the Degenerative Brain Disease CTE Soars by a THIRD Every Year They Play, Study Finds

Daily Mail 10/8/2019

Scary: Study Finds Every Year of Tackle Football Raises Chances of CTE 30%

The Daily Wire 10/8/2019

NFL stars’ risk of developing the degenerative brain disease CTE soars by a THIRD every year they play, study finds

Daily Mail 10/8/2019

CTE Risk Goes Up 30% For Each Year Of Playing Football

Futurity 10/8/2019

BU Research Finds Link Between Playing Football and CTE

WHDH 10/8/2019

CTE Risk in Football Players Doubles Every Five Years, New Study Finds

Boston Magazine 10/7/2019

CTE Risk More Than Doubles after Just Three Years of Playing Football

BU Today 10/7/2019

CTE Risk, Severity Increases With Years Playing Football, Study Shows

Boston Herald 10/7/2019

College Football Season Is Here. Will Universities Continue To Ignore The Risk Of Brain Damage?

Forbes 9/2/2019

New Jersey Unveils New Limits on High School Football Practices

The New York Times 2/13/2019

Cannabis Studied to Treat Conditions from Football-Related Brain Trauma

WeedMaps 2/4/2019

Why We Still Don’t Know How Many NFL Players Have CTE

Five Thirty Eight 12/17/2018

What's the Risk of Chronic Traumatic Encephalopathy for NFL Players?

Inside Science 11/29/2018

Some People May Have Increased CTE Risk Because Of Their Genes

Inquisitr 11/4/2018

Why Some People’s CTE Symptoms Are More Severe Than Others

BU Today 11/3/2018

Why do some people get CTE? It may be in their genes

CNN Todau 11/3/2018

Why Don't All Football Players Develop CTE? It May Be Genetics

WBGH 11/3/2018

MED Researchers: Youth Football Linked to Earlier Brain Problems

BU Today 4/30/2018

2015 Alzheimer’s Association New Investigator Award
2014 Junior Faculty Spivack Neuroscience Scholar
2013 BU ADC Pilot Grant
2011 NIH Clinical Research Loan Repayment Program recipient
2002 National Student Research Forum grant
2002 Maryland House of Delegates Graduate Scholarship recipient
Contact for Mentoring:

72 E. Concord St Robinson (B)
Boston MA 02118
Google Map


Mez's Networks
Click the "See All" links for more information and interactive visualizations
Concepts
_
Media Mentions
_
Co-Authors
_
Similar People
_
Same Department