Dr. Mez completed his undergraduate studies at Cornell University and earned his medical degree from the University of Maryland School of Medicine. He completed residency training in Neurology at Massachusetts General and Brigham and Women’s Hospitals. He completed a clinical fellowship in Aging and Dementia and a research fellowship in Neuroepidemiology at Columbia University. During fellowship training, he also earned a Masters in Biostatistics with a focus on Statistical Genetics from the Mailman School of Public Health at Columbia. In 2013, he became an Assistant Professor of Neurology at Boston University (BU) School of Medicine. In 2014, he became Associate Director of the BU Alzheimer's Disease Center (ADC) Clinical Core.

Research Interests
Dr. Mez’s research seeks to understand genetic, neuropathological, epidemiological and clinical aspects of various forms of dementia. He is the recipient of a K-23 Mentored Patient Oriented Career Development Award that investigates the role of genetic and non-genetic factors in atypical clinical presentations of Alzheimer’s disease. Since 2014, he led the clinical arm of the Understanding Neurologic Injury and Traumatic Encephalopathy (UNITE) study, a U01 project examining the neuropathology and clinical symptoms of brain donors who have experienced repetitive head impacts, including investigating clinicopathological correlation in chronic traumatic encephalopathy (CTE). He also is interested in how the interaction of genetic risk factors and trauma influence dementia risk, particularly chronic traumatic encephalopathy. He also is a Framingham Heart Study (FHS) investigator, leads FHS traumatic brain injury (TBI)-related projects and is involved with reaching consensus dementia diagnoses for FHS participants.

Awards and Memberships
Dr. Mez is a 2015 Spivack Neuroscience Scholar and a recipient of the 2018 Carlos S. Kase Outstanding Contribution to Neurology Research Award. He is a recipient of a Peer Reviewed Alzheimer's Research Project Grant from the Department of Defense, a K23 Mentored Patient-Oriented Research Career Development Award from the National Institute on Aging, a New Investigator Research Grant from the Alzheimer's Association, a BU ADC Pilot Grant, a BU Clinical and Translational Science Institute Pilot Grant and the NIH Loan Repayment Program. He is a member of the American Academy of Neurology, the American Society of Human Genetics, the International Society to Advance Alzheimer’s Research and Treatment and the Society for Behavioral and Cognitive Neurology