David Pimentel | Profiles RNS

David Richard Pimentel, MD

Assistant Professor

Boston University School of Medicine

Dept of Medicine

Cardiovascular Medicine

MD, University of Maryland School of Medicine

Websites

	Boston Medical Center Physician Provider Profile
	BMC Cardiovascular Center

ORCID : 0000-0002-0537-7195

Expertise includes: Oxidative modification; Exosomal communication.

Active Staff Hospital Privileges
Boston Medical Center
Medicine

BMC Sponsored Research
NIH RePORTER Sponsored Research

Ventrizular Remodeling from H202 in Mechanical Overload
09/30/2005 - 08/31/2010 (PI)
NIH-NHLBI
5 K08 HL071563-04

Mechanisms of Hydrogen peroxide regulation of MYO
07/01/2003 - 06/30/2008 (PI)
American Heart Assoc

Mechanism of Hydrogen Peroxide induced ventrical
07/01/2002 - 06/30/2004 (PI)
American Heart Assoc

Yr	Title	Project-Sub Proj	Pubs
2009	Ventricular Remodeling from H202 in Mechanical Overload	5K08HL071563-05	4
2008	Ventricular Remodeling from H202 in Mechanical Overload	5K08HL071563-04	4
2007	Ventricular Remodeling from H202 in Mechanical Overload	5K08HL071563-03	4
2006	Ventricular Remodeling from H202 in Mechanical Overload	5K08HL071563-02	4
2005	Ventricular Remodeling from H202 in Mechanical Overload	1K08HL071563-01A1	4

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

Luptak I, Sverdlov AL, Panagia M, Qin F, Pimentel DR, Croteau D, Siwik DA, Ingwall JS, Bachschmid MM, Balschi JA, Colucci WS. Decreased ATP production and myocardial contractile reserve in metabolic heart disease. J Mol Cell Cardiol. 2018 Mar; 116:106-114.View Related Profiles.

Sverdlov, Aaron
Pimentel, David
Siwik, Deborah
Qin, Fuzhong
Luptak, Ivan
Panagia, Marcello
Bachschmid, Markus
Colucci, Wilson

PMID: 29409987; DOI: 10.1016/j.yjmcc.2018.01.017;.

Sverdlov AL, Elezaby A, Qin F, Behring JB, Luptak I, Calamaras TD, Siwik DA, Miller EJ, Liesa M, Shirihai OS, Pimentel DR, Cohen RA, Bachschmid MM, Colucci WS. Mitochondrial Reactive Oxygen Species Mediate Cardiac Structural, Functional, and Mitochondrial Consequences of Diet-Induced Metabolic Heart Disease. J Am Heart Assoc. 2016 Jan 11; 5(1).View Related Profiles.

Sverdlov, Aaron
Elezaby, Aly
Pimentel, David
Siwik, Deborah
Qin, Fuzhong
Luptak, Ivan
Behring, Jessica
Bachschmid, Markus
Shirihai, Orian
Cohen, Richard
Colucci, Wilson

PMID: 26755553; PMCID: PMC4859372; DOI: 10.1161/JAHA.115.002555;.

Brogan A, Ding Y, Pimentel DR, Sam F. Non-invasive imaging for cardiac amyloidosis - delaying the obvious? Int J Cardiol. 2014 Dec 15; 177(2):e87-9.View Related Profiles.

Pimentel, David
Sam, Flora

PMID: 25456697.

Sverdlov AL, Elezaby A, Behring JB, Bachschmid MM, Luptak I, Tu VH, Siwik DA, Miller EJ, Liesa M, Shirihai OS, Pimentel DR, Cohen RA, Colucci WS. High fat, high sucrose diet causes cardiac mitochondrial dysfunction due in part to oxidative post-translational modification of mitochondrial complex II. J Mol Cell Cardiol. 2015 Jan; 78:165-73.View Related Profiles.

Sverdlov, Aaron
Elezaby, Aly
Pimentel, David
Siwik, Deborah
Miller, Edward
Luptak, Ivan
Behring, Jessica
Liesa Roig, Marc
Bachschmid, Markus
Shirihai, Orian
Cohen, Richard
Tu, Vivian
Colucci, Wilson

PMID: 25109264; PMCID: PMC4268348; DOI: 10.1016/j.yjmcc.2014.07.018;.

Qin F, Siwik DA, Pimentel DR, Morgan RJ, Biolo A, Tu VH, Kang YJ, Cohen RA, Colucci WS. Cytosolic H2O2 mediates hypertrophy, apoptosis, and decreased SERCA activity in mice with chronic hemodynamic overload. Am J Physiol Heart Circ Physiol. 2014 May 15; 306(10):H1453-63.View Related Profiles.

Pimentel, David
Siwik, Deborah
Qin, Fuzhong
Cohen, Richard
Morgan, Robert
Tu, Vivian
Colucci, Wilson

PMID: 24633550; PMCID: PMC4024717; DOI: 10.1152/ajpheart.00084.2014;.

Shao D, Fry JL, Han J, Hou X, Pimentel DR, Matsui R, Cohen RA, Bachschmid MM. A redox-resistant sirtuin-1 mutant protects against hepatic metabolic and oxidant stress. J Biol Chem. 2014 Mar 14; 289(11):7293-306.View Related Profiles.

Pimentel, David
Shao, Di
Fry, Jessica
Han, Jingyan
Bachschmid, Markus
Matsui, Reiko
Cohen, Richard

PMID: 24451382; PMCID: PMC3953247; DOI: 10.1074/jbc.M113.520403;.

Essick EE, Wilson RM, Pimentel DR, Shimano M, Baid S, Ouchi N, Sam F. Adiponectin modulates oxidative stress-induced autophagy in cardiomyocytes. PLoS One. 2013; 8(7):e68697.View Related Profiles.

Pimentel, David
Sam, Flora

PMID: 23894332; PMCID: PMC3716763; DOI: 10.1371/journal.pone.0068697;.

Haeussler DJ, Pimentel DR, Hou X, Burgoyne JR, Cohen RA, Bachschmid MM. Endomembrane H-Ras controls vascular endothelial growth factor-induced nitric-oxide synthase-mediated endothelial cell migration. J Biol Chem. 2013 May 24; 288(21):15380-9.View Related Profiles.

Haeussler, Dagmar
Pimentel, David
Burgoyne, Joseph
Bachschmid, Markus
Cohen, Richard

PMID: 23548900; PMCID: PMC3663556; DOI: 10.1074/jbc.M112.427765;.

Kumar V, Calamaras TD, Haeussler D, Colucci WS, Cohen RA, McComb ME, Pimentel D, Bachschmid MM. Cardiovascular redox and ox stress proteomics. Antioxid Redox Signal. 2012 Dec 1; 17(11):1528-59.View Related Profiles.

Haeussler, Dagmar
Pimentel, David
McComb, Mark
Bachschmid, Markus
Cohen, Richard
Kumar, Vikas
Colucci, Wilson

PMID: 22607061; PMCID: PMC3448941.

Pimentel D, Haeussler DJ, Matsui R, Burgoyne JR, Cohen RA, Bachschmid MM. Regulation of cell physiology and pathology by protein S-glutathionylation: lessons learned from the cardiovascular system. Antioxid Redox Signal. 2012 Mar 15; 16(6):524-42.View Related Profiles.

Haeussler, Dagmar
Pimentel, David
Burgoyne, Joseph
Bachschmid, Markus
Matsui, Reiko
Cohen, Richard

PMID: 22010840; PMCID: PMC3270052; DOI: 10.1089/ars.2011.4336;.

Showing 10 of 55 results. Show More

Bayat H, Schröder K, Pimentel DR, Brandes RP, Verbeuren TJ, Cohen RA, Jiang B. Activation of thromboxane receptor modulates interleukin-1ß-induced monocyte adhesion--a novel role of Nox1. Free Radic Biol Med. 2012 May 1; 52(9):1760-6.View Related Profiles.

Pimentel, David
Cohen, Richard

PMID: 22406435; PMCID: PMC3341499; DOI: 10.1016/j.freeradbiomed.2012.02.052;.

Shimano M, Ouchi N, Nakamura K, van Wijk B, Ohashi K, Asaumi Y, Higuchi A, Pimentel DR, Sam F, Murohara T, van den Hoff MJ, Walsh K. Cardiac myocyte follistatin-like 1 functions to attenuate hypertrophy following pressure overload. Proc Natl Acad Sci U S A. 2011 Oct 25; 108(43):E899-906.View Related Profiles.

Pimentel, David
Sam, Flora
Nakamura, Kazuto
Walsh, Kenneth
Ohashi, Koji
Asaumi, Yasuhide

PMID: 21987816; PMCID: PMC3203781; DOI: 10.1073/pnas.1108559108;.

Haeussler DJ, Evangelista AM, Burgoyne JR, Cohen RA, Bachschmid MM, Pimental DR. Checkpoints in adenoviral production: cross-contamination and E1A. PLoS One. 2011; 6(8):e23160.View Related Profiles.

Haeussler, Dagmar
Pimentel, David
Burgoyne, Joseph
Bachschmid, Markus
Cohen, Richard

PMID: 21826235; PMCID: PMC3149638; DOI: 10.1371/journal.pone.0023160;.

Liesa M, Luptak I, Qin F, Hyde BB, Sahin E, Siwik DA, Zhu Z, Pimentel DR, Xu XJ, Ruderman NB, Huffman KD, Doctrow SR, Richey L, Colucci WS, Shirihai OS. Mitochondrial transporter ATP binding cassette mitochondrial erythroid is a novel gene required for cardiac recovery after ischemia/reperfusion. Circulation. 2011 Aug 16; 124(7):806-13.View Related Profiles.

Pimentel, David
Siwik, Deborah
Qin, Fuzhong
Luptak, Ivan
Xu, Xiaolai
Liesa Roig, Marc
Ruderman, Neil
Shirihai, Orian
Doctrow, Susan
Colucci, Wilson
Xu, Xinjie

PMID: 21788586; DOI: 10.1161/CIRCULATIONAHA.110.003418;.

Essick EE, Ouchi N, Wilson RM, Ohashi K, Ghobrial J, Shibata R, Pimentel DR, Sam F. Adiponectin mediates cardioprotection in oxidative stress-induced cardiac myocyte remodeling. Am J Physiol Heart Circ Physiol. 2011 Sep; 301(3):H984-93.View Related Profiles.

Pimentel, David
Sam, Flora
Ohashi, Koji

PMID: 21666115; PMCID: PMC3191107; DOI: 10.1152/ajpheart.00428.2011;.

Shimano M, Ouchi N, Nakamura K, Oshima Y, Higuchi A, Pimentel DR, Panse KD, Lara-Pezzi E, Lee SJ, Sam F, Walsh K. Cardiac myocyte-specific ablation of follistatin-like 3 attenuates stress-induced myocardial hypertrophy. J Biol Chem. 2011 Mar 18; 286(11):9840-8.View Related Profiles.

Pimentel, David
Sam, Flora
Nakamura, Kazuto
Walsh, Kenneth

PMID: 21245136; PMCID: PMC3058981; DOI: 10.1074/jbc.M110.197079;.

Zee RS, Yoo CB, Pimentel DR, Perlman DH, Burgoyne JR, Hou X, McComb ME, Costello CE, Cohen RA, Bachschmid MM. Redox regulation of sirtuin-1 by S-glutathiolation. Antioxid Redox Signal. 2010 Oct 1; 13(7):1023-32.View Related Profiles.

Costello, Catherine
Pimentel, David
Burgoyne, Joseph
McComb, Mark
Bachschmid, Markus
Cohen, Richard

PMID: 20392170; PMCID: PMC2959181; DOI: 10.1089/ars.2010.3251;.

Shimano M, Ouchi N, Shibata R, Ohashi K, Pimentel DR, Murohara T, Walsh K. Adiponectin deficiency exacerbates cardiac dysfunction following pressure overload through disruption of an AMPK-dependent angiogenic response. J Mol Cell Cardiol. 2010 Aug; 49(2):210-20.View Related Profiles.

Pimentel, David
Walsh, Kenneth
Ohashi, Koji

PMID: 20206634; PMCID: PMC2885542; DOI: 10.1016/j.yjmcc.2010.02.021;.

Ikeda Y, Sato K, Pimentel DR, Sam F, Shaw RJ, Dyck JR, Walsh K. Cardiac-specific deletion of LKB1 leads to hypertrophy and dysfunction. J Biol Chem. 2009 Dec 18; 284(51):35839-49.View Related Profiles.

Pimentel, David
Sam, Flora
Walsh, Kenneth

PMID: 19828446; PMCID: PMC2791013; DOI: 10.1074/jbc.M109.057273;.

Qin F, Lennon-Edwards S, Lancel S, Biolo A, Siwik DA, Pimentel DR, Dorn GW, Kang YJ, Colucci WS. Cardiac-specific overexpression of catalase identifies hydrogen peroxide-dependent and -independent phases of myocardial remodeling and prevents the progression to overt heart failure in G(alpha)q-overexpressing transgenic mice. Circ Heart Fail. 2010 Mar; 3(2):306-13.View Related Profiles.

Pimentel, David
Siwik, Deborah
Qin, Fuzhong
Colucci, Wilson

PMID: 20018955; PMCID: PMC3062519; DOI: 10.1161/CIRCHEARTFAILURE.109.864785;.

Oshima Y, Ouchi N, Shimano M, Pimentel DR, Papanicolaou KN, Panse KD, Tsuchida K, Lara-Pezzi E, Lee SJ, Walsh K. Activin A and follistatin-like 3 determine the susceptibility of heart to ischemic injury. Circulation. 2009 Oct 20; 120(16):1606-15.View Related Profiles.

Pimentel, David
Walsh, Kenneth

PMID: 19805648; PMCID: PMC2764796; DOI: 10.1161/CIRCULATIONAHA.109.872200;.

De Silva DS, Wilson RM, Hutchinson C, Ip PC, Garcia AG, Lancel S, Ito M, Pimentel DR, Sam F. Fenofibrate inhibits aldosterone-induced apoptosis in adult rat ventricular myocytes via stress-activated kinase-dependent mechanisms. Am J Physiol Heart Circ Physiol. 2009 Jun; 296(6):H1983-93.View Related Profiles.

Pimentel, David
Sam, Flora

PMID: 19395558; PMCID: PMC2716095; DOI: 10.1152/ajpheart.00002.2009;.

Kienhöfer J, Häussler DJ, Ruckelshausen F, Muessig E, Weber K, Pimentel D, Ullrich V, Bürkle A, Bachschmid MM. Association of mitochondrial antioxidant enzymes with mitochondrial DNA as integral nucleoid constituents. FASEB J. 2009 Jul; 23(7):2034-44.View Related Profiles.

Pimentel, David
Bachschmid, Markus

PMID: 19228881; PMCID: PMC2704585; DOI: 10.1096/fj.08-113571;.

Miller TA, Icli B, Cote GM, Lebrasseur NK, Borkan SC, Pimentel DR, Peng X, Sawyer DB. Palmitate alters neuregulin signaling and biology in cardiac myocytes. Biochem Biophys Res Commun. 2009 Jan 30; 379(1):32-7.View Related Profiles.

Pimentel, David
Borkan, Steven

PMID: 19070592; PMCID: PMC2654183; DOI: 10.1016/j.bbrc.2008.11.150;.

Oshima Y, Ouchi N, Sato K, Izumiya Y, Pimentel DR, Walsh K. Follistatin-like 1 is an Akt-regulated cardioprotective factor that is secreted by the heart. Circulation. 2008 Jun 17; 117(24):3099-108.View Related Profiles.

Pimentel, David
Walsh, Kenneth

PMID: 18519848; PMCID: PMC2679251; DOI: 10.1161/CIRCULATIONAHA.108.767673;.

Ikeda Y, Ohashi K, Shibata R, Pimentel DR, Kihara S, Ouchi N, Walsh K. Cyclooxygenase-2 induction by adiponectin is regulated by a sphingosine kinase-1 dependent mechanism in cardiac myocytes. FEBS Lett. 2008 Apr 2; 582(7):1147-50.View Related Profiles.

Pimentel, David
Ohashi, Koji

PMID: 18339320; PMCID: PMC2423200; DOI: 10.1016/j.febslet.2008.03.002;.

Lim CC, Yang H, Yang M, Wang CK, Shi J, Berg EA, Pimentel DR, Gwathmey JK, Hajjar RJ, Helmes M, Costello CE, Huo S, Liao R. A novel mutant cardiac troponin C disrupts molecular motions critical for calcium binding affinity and cardiomyocyte contractility. Biophys J. 2008 May 1; 94(9):3577-89.View Related Profiles.

Costello, Catherine
Pimentel, David

PMID: 18212018; PMCID: PMC2292379; DOI: 10.1529/biophysj.107.112896;.

Bayat H, Xu S, Pimentel D, Cohen RA, Jiang B. Activation of thromboxane receptor upregulates interleukin (IL)-1beta-induced VCAM-1 expression through JNK signaling. Arterioscler Thromb Vasc Biol. 2008 Jan; 28(1):127-34.View Related Profiles.

Pimentel, David
Cohen, Richard

PMID: 18032781.

Tong X, Ying J, Pimentel DR, Trucillo M, Adachi T, Cohen RA. High glucose oxidizes SERCA cysteine-674 and prevents inhibition by nitric oxide of smooth muscle cell migration. J Mol Cell Cardiol. 2008 Feb; 44(2):361-9.View Related Profiles.

Pimentel, David
Cohen, Richard
Tong, XiaoYong

PMID: 18164028; PMCID: PMC2394666; DOI: 10.1016/j.yjmcc.2007.10.022;.

An SJ, Boyd R, Zhu M, Chapman A, Pimentel DR, Wang HD. NADPH oxidase mediates angiotensin II-induced endothelin-1 expression in vascular adventitial fibroblasts. Cardiovasc Res. 2007 Sep 1; 75(4):702-9. PMID: 17391658.

Ying J, Tong X, Pimentel DR, Weisbrod RM, Trucillo MP, Adachi T, Cohen RA. Cysteine-674 of the sarco/endoplasmic reticulum calcium ATPase is required for the inhibition of cell migration by nitric oxide. Arterioscler Thromb Vasc Biol. 2007 Apr; 27(4):783-90.View Related Profiles.

Pimentel, David
Cohen, Richard
Tong, XiaoYong

PMID: 17234728.

Kuster GM, Siwik DA, Pimentel DR, Colucci WS. Role of reversible, thioredoxin-sensitive oxidative protein modifications in cardiac myocytes. Antioxid Redox Signal. 2006 Nov-Dec; 8(11-12):2153-9.View Related Profiles.

Pimentel, David
Siwik, Deborah
Colucci, Wilson

PMID: 17034357.

Clavreul N, Bachschmid MM, Hou X, Shi C, Idrizovic A, Ido Y, Pimentel D, Cohen RA. S-glutathiolation of p21ras by peroxynitrite mediates endothelial insulin resistance caused by oxidized low-density lipoprotein. Arterioscler Thromb Vasc Biol. 2006 Nov; 26(11):2454-61.View Related Profiles.

Pimentel, David
Bachschmid, Markus
Cohen, Richard
Ido, Yasuo

PMID: 16931794.

Pimentel DR, Adachi T, Ido Y, Heibeck T, Jiang B, Lee Y, Melendez JA, Cohen RA, Colucci WS. Strain-stimulated hypertrophy in cardiac myocytes is mediated by reactive oxygen species-dependent Ras S-glutathiolation. J Mol Cell Cardiol. 2006 Oct; 41(4):613-22.View Related Profiles.

Pimentel, David
Cohen, Richard
Colucci, Wilson
Ido, Yasuo

PMID: 16806262.

Weaver M, Liu J, Pimentel D, Reddy DJ, Harding P, Peterson EL, Pagano PJ. Adventitial delivery of dominant-negative p67phox attenuates neointimal hyperplasia of the rat carotid artery. Am J Physiol Heart Circ Physiol. 2006 May; 290(5):H1933-41. PMID: 16603705.

Miller TA, LeBrasseur NK, Cote GM, Trucillo MP, Pimentel DR, Ido Y, Ruderman NB, Sawyer DB. Oleate prevents palmitate-induced cytotoxic stress in cardiac myocytes. Biochem Biophys Res Commun. 2005 Oct 14; 336(1):309-15.View Related Profiles.

Pimentel, David
Ruderman, Neil
Ido, Yasuo

PMID: 16126172.

Shibata R, Sato K, Pimentel DR, Takemura Y, Kihara S, Ohashi K, Funahashi T, Ouchi N, Walsh K. Adiponectin protects against myocardial ischemia-reperfusion injury through AMPK- and COX-2-dependent mechanisms. Nat Med. 2005 Oct; 11(10):1096-103.View Related Profiles.

Pimentel, David
Walsh, Kenneth
Ohashi, Koji

PMID: 16155579; PMCID: PMC2828682.

Skurk C, Izumiya Y, Maatz H, Razeghi P, Shiojima I, Sandri M, Sato K, Zeng L, Schiekofer S, Pimentel D, Lecker S, Taegtmeyer H, Goldberg AL, Walsh K. The FOXO3a transcription factor regulates cardiac myocyte size downstream of AKT signaling. J Biol Chem. 2005 May 27; 280(21):20814-23.View Related Profiles.

Pimentel, David
Walsh, Kenneth
Zeng, Ling

PMID: 15781459; PMCID: PMC3632436.

Kuster GM, Pimentel DR, Adachi T, Ido Y, Brenner DA, Cohen RA, Liao R, Siwik DA, Colucci WS. Alpha-adrenergic receptor-stimulated hypertrophy in adult rat ventricular myocytes is mediated via thioredoxin-1-sensitive oxidative modification of thiols on Ras. Circulation. 2005 Mar 8; 111(9):1192-8.View Related Profiles.

Pimentel, David
Siwik, Deborah
Cohen, Richard
Colucci, Wilson
Ido, Yasuo

PMID: 15723974.

Bianchi P, Pimentel DR, Murphy MP, Colucci WS, Parini A. A new hypertrophic mechanism of serotonin in cardiac myocytes: receptor-independent ROS generation. FASEB J. 2005 Apr; 19(6):641-3.View Related Profiles.

Pimentel, David
Colucci, Wilson

PMID: 15703274.

Shibata R, Ouchi N, Ito M, Kihara S, Shiojima I, Pimentel DR, Kumada M, Sato K, Schiekofer S, Ohashi K, Funahashi T, Colucci WS, Walsh K. Adiponectin-mediated modulation of hypertrophic signals in the heart. Nat Med. 2004 Dec; 10(12):1384-9.View Related Profiles.

Pimentel, David
Walsh, Kenneth
Ohashi, Koji
Colucci, Wilson

PMID: 15558058; PMCID: PMC2828675.

Adachi T, Weisbrod RM, Pimentel DR, Ying J, Sharov VS, Schöneich C, Cohen RA. S-Glutathiolation by peroxynitrite activates SERCA during arterial relaxation by nitric oxide. Nat Med. 2004 Nov; 10(11):1200-7.View Related Profiles.

Pimentel, David
Cohen, Richard

PMID: 15489859.

Ito M, Adachi T, Pimentel DR, Ido Y, Colucci WS. Statins inhibit beta-adrenergic receptor-stimulated apoptosis in adult rat ventricular myocytes via a Rac1-dependent mechanism. Circulation. 2004 Jul 27; 110(4):412-8.View Related Profiles.

Pimentel, David
Colucci, Wilson
Ido, Yasuo

PMID: 15262848.

Adachi T, Pimentel DR, Heibeck T, Hou X, Lee YJ, Jiang B, Ido Y, Cohen RA. S-glutathiolation of Ras mediates redox-sensitive signaling by angiotensin II in vascular smooth muscle cells. J Biol Chem. 2004 Jul 9; 279(28):29857-62.View Related Profiles.

Pimentel, David
Cohen, Richard
Ido, Yasuo

PMID: 15123696.

Brenner DA, Jain M, Pimentel DR, Wang B, Connors LH, Skinner M, Apstein CS, Liao R. Human amyloidogenic light chains directly impair cardiomyocyte function through an increase in cellular oxidant stress. Circ Res. 2004 Apr 30; 94(8):1008-10.View Related Profiles.

Pimentel, David
Connors, Lawreen
Skinner, Martha

PMID: 15044325.

Jiang B, Xu S, Hou X, Pimentel DR, Cohen RA. Angiotensin II differentially regulates interleukin-1-beta-inducible NO synthase (iNOS) and vascular cell adhesion molecule-1 (VCAM-1) expression: role of p38 MAPK. J Biol Chem. 2004 May 7; 279(19):20363-8.View Related Profiles.

Pimentel, David
Cohen, Richard

PMID: 15001568.

Heydrick SJ, Weiss N, Thomas SR, Cap AP, Pimentel DR, Loscalzo J, Keaney JF. L-Homocysteine and L-homocystine stereospecifically induce endothelial nitric oxide synthase-dependent lipid peroxidation in endothelial cells. Free Radic Biol Med. 2004 Mar 1; 36(5):632-40.View Related Profiles.

Pimentel, David
Heydrick, Stanley

PMID: 14980706.

Jiang B, Xu S, Hou X, Pimentel DR, Brecher P, Cohen RA. Temporal control of NF-kappaB activation by ERK differentially regulates interleukin-1beta-induced gene expression. J Biol Chem. 2004 Jan 9; 279(2):1323-9.View Related Profiles.

Pimentel, David
Brecher, Peter
Cohen, Richard

PMID: 14581482.

Jain M, Brenner DA, Cui L, Lim CC, Wang B, Pimentel DR, Koh S, Sawyer DB, Leopold JA, Handy DE, Loscalzo J, Apstein CS, Liao R. Glucose-6-phosphate dehydrogenase modulates cytosolic redox status and contractile phenotype in adult cardiomyocytes. Circ Res. 2003 Jul 25; 93(2):e9-16. PMID: 12829617.

Kwon SH, Pimentel DR, Remondino A, Sawyer DB, Colucci WS. H(2)O(2) regulates cardiac myocyte phenotype via concentration-dependent activation of distinct kinase pathways. J Mol Cell Cardiol. 2003 Jun; 35(6):615-21.View Related Profiles.

Pimentel, David
Colucci, Wilson

PMID: 12788379.

Remondino A, Kwon SH, Communal C, Pimentel DR, Sawyer DB, Singh K, Colucci WS. Beta-adrenergic receptor-stimulated apoptosis in cardiac myocytes is mediated by reactive oxygen species/c-Jun NH2-terminal kinase-dependent activation of the mitochondrial pathway. Circ Res. 2003 Feb 7; 92(2):136-8.View Related Profiles.

Pimentel, David
Colucci, Wilson

PMID: 12574140.

Xiao L, Pimentel DR, Wang J, Singh K, Colucci WS, Sawyer DB. Role of reactive oxygen species and NAD(P)H oxidase in alpha(1)-adrenoceptor signaling in adult rat cardiac myocytes. Am J Physiol Cell Physiol. 2002 Apr; 282(4):C926-34.View Related Profiles.

Pimentel, David
Colucci, Wilson

PMID: 11880281.

Sawyer DB, Siwik DA, Xiao L, Pimentel DR, Singh K, Colucci WS. Role of oxidative stress in myocardial hypertrophy and failure. J Mol Cell Cardiol. 2002 Apr; 34(4):379-88.View Related Profiles.

Pimentel, David
Siwik, Deborah
Colucci, Wilson

PMID: 11991728.

Pimentel DR, Amin JK, Xiao L, Miller T, Viereck J, Oliver-Krasinski J, Baliga R, Wang J, Siwik DA, Singh K, Pagano P, Colucci WS, Sawyer DB. Reactive oxygen species mediate amplitude-dependent hypertrophic and apoptotic responses to mechanical stretch in cardiac myocytes. Circ Res. 2001 Aug 31; 89(5):453-60.View Related Profiles.

Pimentel, David
Siwik, Deborah
Colucci, Wilson

PMID: 11532907.

Communal C, Singh K, Pimentel DR, Colucci WS. Norepinephrine stimulates apoptosis in adult rat ventricular myocytes by activation of the beta-adrenergic pathway. Circulation. 1998 Sep 29; 98(13):1329-34.View Related Profiles.

Pimentel, David
Colucci, Wilson

PMID: 9751683.

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 55 publications over 17 distinct years, with a maximum of 7 publications in 2004

Bar chart showing 55 publications over 17 distinct years, with a maximum of 7 publications in 2004

Year	Publications
1998	1
2001	1
2002	2
2003	4
2004	7
2005	5
2006	4
2007	4
2008	4
2009	5
2010	2
2011	5
2012	3
2013	2
2014	4
2016	1
2018	1

In addition to these self-described keywords below, a list of MeSH based concepts is available here.

exosomes
glutathiolation
heart failure

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