David Richard Pimentel, MD
Assistant Professor
Boston University School of Medicine
Dept of Medicine
Cardiovascular Medicine

MD, University of Maryland School of Medicine




Expertise includes: Oxidative modification; Exosomal communication.

Active Staff Hospital Privileges
Boston Medical Center
Medicine





Ventrizular Remodeling from H202 in Mechanical Overload
09/30/2005 - 08/31/2010 (PI)
NIH-NHLBI
5 K08 HL071563-04

Mechanisms of Hydrogen peroxide regulation of MYO
07/01/2003 - 06/30/2008 (PI)
American Heart Assoc

Mechanism of Hydrogen Peroxide induced ventrical
07/01/2002 - 06/30/2004 (PI)
American Heart Assoc


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Luptak I, Morgan R, Baka T, Croteau D, Moverman D, Sarnak H, Kirber M, Bachschmid MM, Colucci WS, Pimentel DR. Genetically Targeted Fluorescent Probes Reveal Dynamic Calcium Responses to Adrenergic Signaling in Multiple Cardiomyocyte Compartments. Int J Biochem Cell Biol. 2019 Jul 09; 105569.View Related Profiles. PMID: 31299273.
     
  2. Luptak I, Qin F, Sverdlov AL, Pimentel DR, Panagia M, Croteau D, Siwik DA, Bachschmid MM, He H, Balschi JA, Colucci WS. Energetic Dysfunction Is Mediated by Mitochondrial Reactive Oxygen Species and Precedes Structural Remodeling in Metabolic Heart Disease. Antioxid Redox Signal. 2019 Jun 25.View Related Profiles. PMID: 31088291.
     
  3. Luptak I, Sverdlov AL, Panagia M, Qin F, Pimentel DR, Croteau D, Siwik DA, Ingwall JS, Bachschmid MM, Balschi JA, Colucci WS. Decreased ATP production and myocardial contractile reserve in metabolic heart disease. J Mol Cell Cardiol. 2018 03; 116:106-114.View Related Profiles. PMID: 29409987; DOI: 10.1016/j.yjmcc.2018.01.017;.
     
  4. Sverdlov AL, Elezaby A, Qin F, Behring JB, Luptak I, Calamaras TD, Siwik DA, Miller EJ, Liesa M, Shirihai OS, Pimentel DR, Cohen RA, Bachschmid MM, Colucci WS. Mitochondrial Reactive Oxygen Species Mediate Cardiac Structural, Functional, and Mitochondrial Consequences of Diet-Induced Metabolic Heart Disease. J Am Heart Assoc. 2016 Jan 11; 5(1).View Related Profiles. PMID: 26755553; PMCID: PMC4859372; DOI: 10.1161/JAHA.115.002555;.
     
  5. Brogan A, Ding Y, Pimentel DR, Sam F. Non-invasive imaging for cardiac amyloidosis - delaying the obvious? Int J Cardiol. 2014 Dec 15; 177(2):e87-9.View Related Profiles. PMID: 25456697.
     
  6. Sverdlov AL, Elezaby A, Behring JB, Bachschmid MM, Luptak I, Tu VH, Siwik DA, Miller EJ, Liesa M, Shirihai OS, Pimentel DR, Cohen RA, Colucci WS. High fat, high sucrose diet causes cardiac mitochondrial dysfunction due in part to oxidative post-translational modification of mitochondrial complex II. J Mol Cell Cardiol. 2015 Jan; 78:165-73.View Related Profiles. PMID: 25109264; PMCID: PMC4268348; DOI: 10.1016/j.yjmcc.2014.07.018;.
     
  7. Qin F, Siwik DA, Pimentel DR, Morgan RJ, Biolo A, Tu VH, Kang YJ, Cohen RA, Colucci WS. Cytosolic H2O2 mediates hypertrophy, apoptosis, and decreased SERCA activity in mice with chronic hemodynamic overload. Am J Physiol Heart Circ Physiol. 2014 May 15; 306(10):H1453-63.View Related Profiles. PMID: 24633550; PMCID: PMC4024717; DOI: 10.1152/ajpheart.00084.2014;.
     
  8. Shao D, Fry JL, Han J, Hou X, Pimentel DR, Matsui R, Cohen RA, Bachschmid MM. A redox-resistant sirtuin-1 mutant protects against hepatic metabolic and oxidant stress. J Biol Chem. 2014 Mar 14; 289(11):7293-306.View Related Profiles. PMID: 24451382; PMCID: PMC3953247; DOI: 10.1074/jbc.M113.520403;.
     
  9. Essick EE, Wilson RM, Pimentel DR, Shimano M, Baid S, Ouchi N, Sam F. Adiponectin modulates oxidative stress-induced autophagy in cardiomyocytes. PLoS One. 2013; 8(7):e68697.View Related Profiles. PMID: 23894332; PMCID: PMC3716763; DOI: 10.1371/journal.pone.0068697;.
     
  10. Haeussler DJ, Pimentel DR, Hou X, Burgoyne JR, Cohen RA, Bachschmid MM. Endomembrane H-Ras controls vascular endothelial growth factor-induced nitric-oxide synthase-mediated endothelial cell migration. J Biol Chem. 2013 May 24; 288(21):15380-9.View Related Profiles. PMID: 23548900; PMCID: PMC3663556; DOI: 10.1074/jbc.M112.427765;.
     
Showing 10 of 57 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 57 publications over 18 distinct years, with a maximum of 7 publications in 2004

YearPublications
19981
20011
20022
20034
20047
20055
20064
20074
20084
20095
20102
20115
20123
20132
20144
20161
20181
20192
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

exosomes
glutathiolation
heart failure
Contact for Mentoring:


650 Albany St Evans Biomed Research Ctr
Boston MA 02118
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