Alexa Beiser, PhD
Professor
Boston University School of Public Health
Dept of Biostatistics

PhD, Boston University
MA, University of California, San Diego




Alexa Beiser has been on the faculty at Boston University School of Public Health since 1985, engaged in teaching and collaborative public health research; she co-developed the doctoral program in biostatistics; co-directed the biostatistics program from 2000-2004, and served as Associate Chair for Education from 2015-2018. She formerly taught and coordinated the sections of Introduction to Statistical Computing. For more than twenty-five years, Dr. Beiser has served as the lead biostatistician for the Framingham Heart Study (FHS) neurology group, examining risk factors and prevalence and incidence of clinical and sub-clinical neurological outcomes including MRI and PET measures of brain structure, cognitive performance, dementia, Alzheimer’s disease, stroke, Parkinson’s disease, and epilepsy. Dr. Beiser currently leads the FHS neurology group data management team, responsible for surveillance and tracking of incident dementia, for supervision of recruitment of participants for various grant-funded studies, and for management of data collected at FHS as well as those measured or processed at other institutions (e.g., brain MRI or PET scans); and the FHS neurology group biostatistics team of six biostatisticians. Decades of examining risk factors for neurological diseases has naturally led to studying factors associated with accelerated brain aging. Dr. Beiser has coauthored FHS publications relating risk factors including midlife vascular factors, plasma homocysteine, plasma leptin levels, cardiac index, red blood cell omega-3 fatty acids, metabolic dysregulation, visceral fat, air pollution; serum brain-derived neurotrophic factor; and insulin-like growth factor 1, to measures of brain aging. Dr. Beiser also has made use of the richness of the multigenerational Framingham data to relate documented parental dementia and stroke to offspring stroke, cognitive performance, and MRI measures of brain structure. In investigations of clinical neurological endpoints, she has applied competing risk analyses and has also been able to investigate temporal trends in prevalent and incident neurological disease due to the availability of event surveillance over many decades. In all these studies, Dr. Beiser plays a key role in project conceptualization, is responsible for supervision of statistical data management, analysis, and interpretation of results, and contributes to manuscript preparation and critical review.

Professor
Boston University School of Medicine
Neurology


Investigator
Framingham Heart Study


Associate Chair
Boston University School of Public Health
Biostatistics


Boston Medical Center




Microglial, Inflammatory and Omics Markers of Cerebral Small Vessel Disease in the CHARGE Consortium
09/15/2018 - 07/31/2021 (Subcontract PI)
University of Texas Health Science Center at San Antonio NIH NINDS
5UH3NS100605-04

Temporal Trends, Novel Imaging and Molecular Characterization of Preclinical and Clinical Alzheimer Disease in Framingham Cohorts
12/01/2017 - 05/31/2021 (Subcontract PI)
University of Texas Health Science Center at San Antonio NIH NIA
7R01AG054076-04

Microglial, Inflammatory and Omics Markers of Cerebral Small Vessel Disease in the CHARGE Consortium
12/01/2017 - 09/14/2018 (Subcontract PI)
University of Texas Health Science Center at San Antonio NIH NINDS
7UH3NS100605-03



Title


Yr Title Project-Sub Proj Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Stefanidou M, Beiser AS, Himali JJ, Peng TJ, Devinsky O, Seshadri S, Friedman D. The bi-directional association between epilepsy and dementia. The Framingham Heart Study. Neurology. 2020 Oct 23.View Related Profiles. PMID: 33097599; DOI: 10.1212/WNL.0000000000011077;
     
  2. Hofer E, Roshchupkin GV, Adams HHH, Knol MJ, Lin H, Li S, Zare H, Ahmad S, Armstrong NJ, Satizabal CL, Bernard M, Bis JC, Gillespie NA, Luciano M, Mishra A, Scholz M, Teumer A, Xia R, Jian X, Mosley TH, Saba Y, Pirpamer L, Seiler S, Becker JT, Carmichael O, Rotter JI, Psaty BM, Lopez OL, Amin N, van der Lee SJ, Yang Q, Himali JJ, Maillard P, Beiser AS, DeCarli C, Karama S, Lewis L, Harris M, Bastin ME, Deary IJ, Veronica Witte A, Beyer F, Loeffler M, Mather KA, Schofield PR, Thalamuthu A, Kwok JB, Wright MJ, Ames D, Trollor J, Jiang J, Brodaty H, Wen W, Vernooij MW, Hofman A, Uitterlinden AG, Niessen WJ, Wittfeld K, Bülow R, Völker U, Pausova Z, Bruce Pike G, Maingault S, Crivello F, Tzourio C, Amouyel P, Mazoyer B, Neale MC, Franz CE, Lyons MJ, Panizzon MS, Andreassen OA, Dale AM, Logue M, Grasby KL, Jahanshad N, Painter JN, Colodro-Conde L, Bralten J, Hibar DP, Lind PA, Pizzagalli F, Stein JL, Thompson PM, Medland SE, Sachdev PS, Kremen WS, Wardlaw JM, Villringer A, van Duijn CM, Grabe HJ, Longstreth WT, Fornage M, Paus T, Debette S, Arfan Ikram M, Schmidt H, Schmidt R, Seshadri S. Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults. Nat Commun. 2020 09 22; 11(1):4796.View Related Profiles. PMID: 32963231; DOI: 10.1038/s41467-020-18367-y;
     
  3. McGrath ER, Himali JJ, Levy D, Conner SC, DeCarli C, Pase MP, Ninomiya T, Ohara T, Courchesne P, Satizabal CL, Vasan RS, Beiser AS, Seshadri S. Growth Differentiation Factor 15 and NT-proBNP as Blood-Based Markers of Vascular Brain Injury and Dementia. J Am Heart Assoc. 2020 Oct 20; 9(19):e014659.View Related Profiles. PMID: 32921207
     
  4. Knol MJ, Lu D, Traylor M, Adams HH, Rafael J Romero J, Smith AV, Fornage M, Hofer E, Liu J, Hostettler IC, Luciano M, Trompet S, Giese AK, Hilal S, van den Akker EB, Vojinovic D, Li S, Sigurdsson S, van der Lee SJ, Jack CR, Wilson D, Yilmaz P, Satizabal CL, Liewald DCM, van der Grond J, Chen C, Saba Y, van der Lugt A, Bastin ME, Windham BG, Cheng CY, Pirpamer L, Kantarci K, Himali JJ, Yang Q, Morris Z, Beiser AS, Tozer DJ, Vernooij MW, Amin N, Beekman M, Koh JY, Stott DJ, Houlden H, Schmidt R, Gottesman RF, MacKinnon AD, DeCarli C, Gudnason V, Deary IJ, van Duijn CM, Slagboom PE, Wong TY, Rost NS, Jukema JW, Mosley TH, Werring DJ, Schmidt H, Wardlaw JM, Ikram MA, Seshadri S, Launer LJ, Markus HS. Association of common genetic variants with brain microbleeds: A Genome-wide Association Study. Neurology. 2020 Sep 10.View Related Profiles. PMID: 32913026
     
  5. Baril AA, Beiser AS, Redline S, McGrath ER, Aparicio HJ, Gottlieb DJ, Seshadri S, Pase MP, Himali JJ. Systemic Inflammation as a Moderator Between Sleep and Incident Dementia. Sleep. 2020 Aug 29.View Related Profiles. PMID: 32860698
     
  6. Petrea RE, O'Donnell A, Beiser AS, Habes M, Aparicio H, DeCarli C, Seshadri S, Romero JR. Mid to Late Life Hypertension Trends and Cerebral Small Vessel Disease in the Framingham Heart Study. Hypertension. 2020 Sep; 76(3):707-714.View Related Profiles. PMID: 32755403
     
  7. Peloso GM, Beiser AS, Satizabal CL, Xanthakis V, Vasan RS, Pase MP, Destefano AL, Seshadri S. Cardiovascular health, genetic risk, and risk of dementia in the Framingham Heart Study. Neurology. 2020 09 08; 95(10):e1341-e1350.View Related Profiles. PMID: 32690788
     
  8. Wolters FJ, Chibnik LB, Waziry R, Anderson R, Berr C, Beiser A, Bis JC, Blacker D, Bos D, Brayne C, Dartigues JF, Darweesh SKL, Davis-Plourde KL, de Wolf F, Debette S, Dufouil C, Fornage M, Goudsmit J, Grasset L, Gudnason V, Hadjichrysanthou C, Helmer C, Ikram MA, Ikram MK, Joas E, Kern S, Kuller LH, Launer L, Lopez OL, Matthews FE, McRae-McKee K, Meirelles O, Mosley TH, Pase MP, Psaty BM, Satizabal CL, Seshadri S, Skoog I, Stephan BCM, Wetterberg H, Wong MM, Zettergren A, Hofman A. Twenty-seven-year time trends in dementia incidence in Europe and the United States: The Alzheimer Cohorts Consortium. Neurology. 2020 08 04; 95(5):e519-e531.View Related Profiles. PMID: 32611641
     
  9. Romero JR, Demissie S, Beiser A, Himali JJ, DeCarli C, Levy D, Seshadri S. Relation of plasma ß-amyloid, clusterin, and tau with cerebral microbleeds: Framingham Heart Study. Ann Clin Transl Neurol. 2020 07; 7(7):1083-1091.View Related Profiles. PMID: 32588552
     
  10. Armstrong NJ, Mather KA, Sargurupremraj M, Knol MJ, Malik R, Satizabal CL, Yanek LR, Wen W, Gudnason VG, Dueker ND, Elliott LT, Hofer E, Bis J, Jahanshad N, Li S, Logue MA, Luciano M, Scholz M, Smith AV, Trompet S, Vojinovic D, Xia R, Alfaro-Almagro F, Ames D, Amin N, Amouyel P, Beiser AS, Brodaty H, Deary IJ, Fennema-Notestine C, Gampawar PG, Gottesman R, Griffanti L, Jack CR, Jenkinson M, Jiang J, Kral BG, Kwok JB, Lampe L, C M Liewald D, Maillard P, Marchini J, Bastin ME, Mazoyer B, Pirpamer L, Rafael Romero J, Roshchupkin GV, Schofield PR, Schroeter ML, Stott DJ, Thalamuthu A, Trollor J, Tzourio C, van der Grond J, Vernooij MW, Witte VA, Wright MJ, Yang Q, Morris Z, Siggurdsson S, Psaty B, Villringer A, Schmidt H, Haberg AK, van Duijn CM, Jukema JW, Dichgans M, Sacco RL, Wright CB, Kremen WS, Becker LC, Thompson PM, Mosley TH, Wardlaw JM, Ikram MA, Adams HHH, Seshadri S, Sachdev PS, Smith SM, Launer L, Longstreth W, DeCarli C, Schmidt R, Fornage M, Debette S, Nyquist PA. Common Genetic Variation Indicates Separate Causes for Periventricular and Deep White Matter Hyperintensities. Stroke. 2020 07; 51(7):2111-2121.View Related Profiles. PMID: 32517579
     
Showing 10 of 290 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 290 publications over 34 distinct years, with a maximum of 29 publications in 2017

YearPublications
19841
19861
19882
19891
19914
19921
19937
19943
19953
19962
19974
19985
19994
20006
20013
20025
20035
200410
20054
20068
20074
20085
200911
20109
20118
201211
201315
201414
201525
201626
201729
201814
201926
202014

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72 E. Concord St Robinson (B)
Boston MA 02118
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