Tamar R. Aprahamian, PhD
Assistant Professor
Boston University School of Medicine
Dept of Medicine
Nephrology

PhD, Tufts University



Tamar Aprahamian, PhD is an Assistant Professor of Nephrology at the Boston University School of Medicine. Dr. Aprahamian returned to the university in 2017, after a year-long stint as Principal Scientist for Cobalt Biomedicine, where she was named as inventor on 9 patents and led the preclinical development, design, and analysis of data. She is also the founder of JetPub Scientific Communications. The company specializes in writing services for academic institutions, pharmaceutical, biotechnology, and medical device companies.

Dr. Aprahamian's research interests are influenced by her 12 years in the BUSM renal section and include adipose tissue biology, in vivo efficacy testing, and drug target validation.

Boston Medical Center




CARDIOVAX PROJECT
11/01/2013 - 12/31/2016 (PI)
CardioVax

CARDIOVAX PROJECT
11/01/2013 - 12/31/2016 (PI)
CardioVax

ANGIOGENIC POTENTIAL AND THERMOGENIC RESPONSE OF BROWN ADIPOSE TISSUE
04/01/2012 - 03/31/2015 (PI)
Boston Medical Center Corporation NIH NIDDK
5P30DK046200-22

ANGIOGENIC POTENTIAL AND THERMOGENIC RESPONSE OF BROWN ADIPOSE TISSUE
04/01/2012 - 03/31/2015 (PI)
Boston Medical Center Corporation NIH NIDDK
5P30DK046200-22

THE ROLE OF RETINALDEHYDE AND ADIPOGENESIS IN THE PROGRESSION OF SYSTEMIC LUPUS ERYTHEMATOS
06/01/2014 - 08/15/2014 (PI)
The Lupus Foundation of America, Inc.

THE ROLE OF RETINALDEHYDE AND ADIPOGENESIS IN THE PROGRESSION OF SYSTEMIC LUPUS ERYTHEMATOS
06/01/2014 - 08/15/2014 (PI)
The Lupus Foundation of America, Inc.

A Novel Mouse Model to Study Accelerated Atherosclerosis in SLE: A Possible Role for Statin Treatment
06/01/2004 - 09/01/2004 (PI)
The Lupus Foundation of America, Inc.


Role of PPARgamma signaling and adiponectin in Systemic Lupus Erythematosus
07/01/2009 - 06/30/2015 (PI)
NIH-NIAMS
5K01 AR055965-05


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. MacLauchlan S, Zuriaga MA, Fuster JJ, Cuda CM, Jonason J, Behzadi F, Duffen JP, Haines GK, Aprahamian T, Perlman H, Walsh K. Genetic deficiency of Wnt5a diminishes disease severity in a murine model of rheumatoid arthritis. Arthritis Res Ther. 2017 Jul 19; 19(1):166.View Related Profiles. PMID: 28724439; DOI: 10.1186/s13075-017-1375-0;.
     
  2. Mahdaviani K, Benador IY, Su S, Gharakhanian RA, Stiles L, Trudeau KM, Cardamone M, Enríquez-Zarralanga V, Ritou E, Aprahamian T, Oliveira MF, Corkey BE, Perissi V, Liesa M, Shirihai OS. Mfn2 deletion in brown adipose tissue protects from insulin resistance and impairs thermogenesis. EMBO Rep. 2017 Jul; 18(7):1123-1138.View Related Profiles. PMID: 28539390.
     
  3. Wang H, Liu L, Lin JZ, Aprahamian TR, Farmer SR. Browning of White Adipose Tissue with Roscovitine Induces a Distinct Population of UCP1+ Adipocytes. Cell Metab. 2016 Dec 13; 24(6):835-847.View Related Profiles. PMID: 27974179; DOI: 10.1016/j.cmet.2016.10.005;.
     
  4. Valero-Muñoz M, Li S, Wilson RM, Hulsmans M, Aprahamian T, Fuster JJ, Nahrendorf M, Scherer PE, Sam F. Heart Failure With Preserved Ejection Fraction Induces Beiging in Adipose Tissue. Circ Heart Fail. 2016 Jan; 9(1):e002724.View Related Profiles. PMID: 26721917; PMCID: PMC4698901; DOI: 10.1161/CIRCHEARTFAILURE.115.002724;.
     
  5. Duffau P, Menn-Josephy H, Cuda CM, Dominguez S, Aprahamian TR, Watkins AA, Yasuda K, Monach P, Lafyatis R, Rice LM, Kenneth Haines G, Gravallese EM, Baum R, Richez C, Perlman H, Bonegio RG, Rifkin IR. Promotion of Inflammatory Arthritis by Interferon Regulatory Factor 5 in a Mouse Model. Arthritis Rheumatol. 2015 Dec; 67(12):3146-57.View Related Profiles. PMID: 26315890; PMCID: PMC4661118; DOI: 10.1002/art.39321;.
     
  6. Mahdaviani K, Chess D, Wu Y, Shirihai O, Aprahamian TR. Autocrine effect of vascular endothelial growth factor-A is essential for mitochondrial function in brown adipocytes. Metabolism. 2016 Jan; 65(1):26-35.View Related Profiles. PMID: 26683794; PMCID: PMC4684900; DOI: 10.1016/j.metabol.2015.09.012;.
     
  7. Kambara T, Shibata R, Ohashi K, Matsuo K, Hiramatsu-Ito M, Enomoto T, Yuasa D, Ito M, Hayakawa S, Ogawa H, Aprahamian T, Walsh K, Murohara T, Ouchi N. C1q/Tumor Necrosis Factor-Related Protein 9 Protects against Acute Myocardial Injury through an Adiponectin Receptor I-AMPK-Dependent Mechanism. Mol Cell Biol. 2015 Jun; 35(12):2173-85.View Related Profiles. PMID: 25870106; PMCID: PMC4438248; DOI: 10.1128/MCB.01518-14;.
     
  8. Aprahamian TR, Zhong X, Amir S, Binder CJ, Chiang LK, Al-Riyami L, Gharakhanian R, Harnett MM, Harnett W, Rifkin IR. The immunomodulatory parasitic worm product ES-62 reduces lupus-associated accelerated atherosclerosis in a mouse model. Int J Parasitol. 2015 Mar; 45(4):203-7.View Related Profiles. PMID: 25666929; PMCID: PMC4355381; DOI: 10.1016/j.ijpara.2014.12.006;.
     
  9. Watkins AA, Yasuda K, Wilson GE, Aprahamian T, Xie Y, Maganto-Garcia E, Shukla P, Oberlander L, Laskow B, Menn-Josephy H, Wu Y, Duffau P, Fried SK, Lichtman AH, Bonegio RG, Rifkin IR. IRF5 deficiency ameliorates lupus but promotes atherosclerosis and metabolic dysfunction in a mouse model of lupus-associated atherosclerosis. J Immunol. 2015 Feb 15; 194(4):1467-79.View Related Profiles. PMID: 25595782; PMCID: PMC4323680; DOI: 10.4049/jimmunol.1402807;.
     
  10. Fuster JJ, Zuriaga MA, Ngo DT, Farb MG, Aprahamian T, Yamaguchi TP, Gokce N, Walsh K. Noncanonical Wnt signaling promotes obesity-induced adipose tissue inflammation and metabolic dysfunction independent of adipose tissue expansion. Diabetes. 2015 Apr; 64(4):1235-48.View Related Profiles. PMID: 25352637; PMCID: PMC4375084; DOI: 10.2337/db14-1164;.
     
Showing 10 of 36 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 36 publications over 13 distinct years, with a maximum of 5 publications in 2008 and 2015

YearPublications
20032
20044
20063
20071
20085
20092
20101
20113
20132
20144
20155
20162
20172
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Animal models

Available to Mentor as: (Review Mentor Role Definitions):
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650 Albany St Evans Biomed Research Ctr
Boston MA 02118
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