Maria Valero Munoz | Profiles RNS

Maria Valero Munoz, PhD

Assistant Professor

Boston University Chobanian & Avedisian School of Medicine

Whitaker Cardiovascular Institute

PhD, Complutense De Madrid
MS, Complutense De Madrid
BS, Complutense De Madrid

Websites

	Sam Lab
	Google Scholar
	Loop Frontiers
	LinkedIn

ORCID : 0000-0002-1412-7366

BU Research

Mechanistic underpinnings of increased adipose tissue in HFpEF
07/01/2019 - 06/30/2025 (Key Person)
PI: Flora Sam, MD
NIH/National Heart, Lung, and Blood Institute
5R01HL145985-04

Translational regulators of adipose tissue in HFpEF
07/01/2017 - 06/30/2019 (PI)
American Heart Association

Title

Yr	Title	Project-Sub Proj	Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis Copy PMIDs To Clipboard

Saw EL, Ramachandran S, Valero-Muñoz M, Sam F. Skeletal muscle (dys)function in heart failure with preserved ejection fraction. Curr Opin Cardiol. 2021 03 01; 36(2):219-226.View Related Profiles.

Saw, Eng
Sam, Flora
Valero Munoz, Maria
Ramachandran, Swetha

PMID: 33394707; PMCID: PMC7895420; DOI: 10.1097/HCO.0000000000000824;

Valero-Muñoz M, Sam F. Reply to letter by Ye et al., blocking lncRNA H19/miR-194-5p/SIRT1 axis in cardiac myocyte is responsible for doxycycline inhibiting autophagy. Int J Cardiol. 2021 05 15; 331:213.View Related Profiles.

Sam, Flora
Valero Munoz, Maria

PMID: 33515616

Valero-Muñoz M, Sam F. Reply to letter by Hou et al., Doxycycline ameliorates autophagy by inhibiting p38 MAPK in cardiac myocytes. Int J Cardiol. 2021 05 15; 331:212.View Related Profiles.

Sam, Flora
Valero Munoz, Maria

PMID: 33515614

Valero-Muñoz M, Wilson RM, Bretón-Romero R, Croteau D, Seldin DC, Sam F. Doxycycline decreases amyloidogenic light chain-induced autophagy in isolated primary cardiac myocytes. Int J Cardiol. 2020 12 15; 321:133-136.View Related Profiles.

Sam, Flora
Valero Munoz, Maria

PMID: 32682005; PMCID: PMC9020138; DOI: 10.1016/j.ijcard.2020.07.016;

Oh A, Okazaki R, Sam F, Valero-Muñoz M. Heart Failure With Preserved Ejection Fraction and Adipose Tissue: A Story of Two Tales. Front Cardiovasc Med. 2019; 6:110.View Related Profiles.

Oh, Albin
Sam, Flora
Valero Munoz, Maria

PMID: 31428620; PMCID: PMC6687767; DOI: 10.3389/fcvm.2019.00110;

Valero-Muñoz M, Sam F. Reply: Diet-Induced Obesity HFpEF Murine Models. JACC Basic Transl Sci. 2018 Feb; 3(1):158-159.View Related Profiles.

Sam, Flora
Valero Munoz, Maria

PMID: 30062201; PMCID: PMC6059000; DOI: 10.1016/j.jacbts.2018.01.006;

Hulsmans M, Sager HB, Roh JD, Valero-Muñoz M, Houstis NE, Iwamoto Y, Sun Y, Wilson RM, Wojtkiewicz G, Tricot B, Osborne MT, Hung J, Vinegoni C, Naxerova K, Sosnovik DE, Zile MR, Bradshaw AD, Liao R, Tawakol A, Weissleder R, Rosenzweig A, Swirski FK, Sam F, Nahrendorf M. Cardiac macrophages promote diastolic dysfunction. J Exp Med. 2018 02 05; 215(2):423-440.View Related Profiles.

Sam, Flora
Valero Munoz, Maria

PMID: 29339450; PMCID: PMC5789416; DOI: 10.1084/jem.20171274;

Valero-Muñoz M, Backman W, Sam F. Murine Models of Heart Failure with Preserved Ejection Fraction: a "Fishing Expedition". JACC Basic Transl Sci. 2017 Dec; 2(6):770-789.View Related Profiles.

Sam, Flora
Valero Munoz, Maria

PMID: 29333506; PMCID: PMC5764178; DOI: 10.1016/j.jacbts.2017.07.013;

Valero-Muñoz M, Ballesteros S, Ruiz-Roso B, Pérez-Olleros L, Martín-Fernández B, Lahera V, de Las Heras N. Supplementation with an insoluble fiber obtained from carob pod (Ceratonia siliqua L.) rich in polyphenols prevents dyslipidemia in rabbits through SIRT1/PGC-1a pathway. Eur J Nutr. 2019 Feb; 58(1):357-366. PMID: 29274033; DOI: 10.1007/s00394-017-1599-4;

de Las Heras N, Valero-Muñoz M, Martín-Fernández B, Ballesteros S, López-Farré A, Ruiz-Roso B, Lahera V. Molecular factors involved in the hypolipidemic- and insulin-sensitizing effects of a ginger (Zingiber officinale Roscoe) extract in rats fed a high-fat diet. Appl Physiol Nutr Metab. 2017 Feb; 42(2):209-215. PMID: 28125276; DOI: 10.1139/apnm-2016-0374;

Showing 10 of 26 results. Show More

Valero-Munoz M, Li S, Wilson RM, Boldbaatar B, Iglarz M, Sam F. Dual Endothelin-A/Endothelin-B Receptor Blockade and Cardiac Remodeling in Heart Failure With Preserved Ejection Fraction. Circ Heart Fail. 2016 Nov; 9(11).View Related Profiles.

Boldbaatar, Batbold
Sam, Flora
Valero Munoz, Maria

PMID: 27810862; PMCID: PMC5584628; DOI: 10.1161/CIRCHEARTFAILURE.116.003381;

Tanaka K, Valero-Muñoz M, Wilson RM, Essick EE, Fowler CT, Nakamura K, van den Hoff M, Ouchi N, Sam F. Follistatin like 1 Regulates Hypertrophy in Heart Failure with Preserved Ejection Fraction. JACC Basic Transl Sci. 2016 Jun; 1(4):207-221.View Related Profiles.

Sam, Flora
Nakamura, Kazuto
Tanaka, Komei
Valero Munoz, Maria

PMID: 27430031; PMCID: PMC4944656; DOI: 10.1016/j.jacbts.2016.04.002;

Valero-Muñoz M, Li S, Wilson RM, Hulsmans M, Aprahamian T, Fuster JJ, Nahrendorf M, Scherer PE, Sam F. Heart Failure With Preserved Ejection Fraction Induces Beiging in Adipose Tissue. Circ Heart Fail. 2016 Jan; 9(1):e002724.View Related Profiles.

Sam, Flora
Fuster Ortuno, Jose
Valero Munoz, Maria
Aprahamian, Tamar

PMID: 26721917; PMCID: PMC4698901; DOI: 10.1161/CIRCHEARTFAILURE.115.002724;

López-Ibarra Z, Modrego J, Valero-Muñoz M, Rodríguez-Sierra P, Zamorano-León JJ, González-Cantalapiedra A, de Las Heras N, Ballesteros S, Lahera V, López-Farré AJ. Metabolic differences between white and brown fat from fasting rabbits at physiological temperature. J Mol Endocrinol. 2015 Apr; 54(2):105-13. PMID: 25701828; DOI: 10.1530/JME-14-0255;

Martín-Fernández B, de las Heras N, Valero-Muñoz M, Ballesteros S, Yao YZ, Stanton PG, Fuller PJ, Lahera V. Beneficial effects of proanthocyanidins in the cardiac alterations induced by aldosterone in rat heart through mineralocorticoid receptor blockade. PLoS One. 2014; 9(10):e111104. PMID: 25353961; PMCID: PMC4212985; DOI: 10.1371/journal.pone.0111104;

Valero-Muñoz M, Martín-Fernández B, Ballesteros S, Lahera V, de las Heras N. Carob pod insoluble fiber exerts anti-atherosclerotic effects in rabbits through sirtuin-1 and peroxisome proliferator-activated receptor-? coactivator-1a. J Nutr. 2014 Sep; 144(9):1378-84. PMID: 25031331; DOI: 10.3945/jn.114.196113;

Martín-Fernández B, Valero Muñoz M, de las Heras N, Ballesteros S, Lahera V. Relevance of SGK1 in structural, functional and molecular alterations produced by aldosterone in heart. Horm Mol Biol Clin Investig. 2014 May; 18(2):53-61. PMID: 25390002; DOI: 10.1515/hmbci-2013-0052;

Martínez-Martínez E, Jurado-López R, Valero-Muñoz M, Bartolomé MV, Ballesteros S, Luaces M, Briones AM, López-Andrés N, Miana M, Cachofeiro V. Leptin induces cardiac fibrosis through galectin-3, mTOR and oxidative stress: potential role in obesity. J Hypertens. 2014 May; 32(5):1104-14; discussion 1114. PMID: 24695395; DOI: 10.1097/HJH.0000000000000149;

Valero-Muñoz M, Martín-Fernández B, Ballesteros S, Cachofeiro V, Lahera V, de Las Heras N. [Rosuvastatin improves insulin sensitivity in overweight rats induced by high fat diet. Role of SIRT1 in adipose tissue]. Clin Investig Arterioscler. 2014 Jul-Aug; 26(4):161-7. PMID: 24612843; DOI: 10.1016/j.arteri.2013.12.005;

Valero-Muñoz M, Martín-Fernández B, Ballesteros S, de la Fuente E, Quintela JC, Lahera V, de las Heras N. Protective effect of a pomace olive oil concentrated in triterpenic acids in alterations related to hypertension in rats: mechanisms involved. Mol Nutr Food Res. 2014 Feb; 58(2):376-83. PMID: 24039161; DOI: 10.1002/mnfr.201300256;

Stefanon I, Valero-Muñoz M, Fernandes AA, Ribeiro RF, Rodríguez C, Miana M, Martínez-González J, Spalenza JS, Lahera V, Vassallo PF, Cachofeiro V. Left and right ventricle late remodeling following myocardial infarction in rats. PLoS One. 2013; 8(5):e64986. PMID: 23741440; PMCID: PMC3669026; DOI: 10.1371/journal.pone.0064986;

Gómez-Arbeláez D, Lahera V, Oubiña P, Valero-Muñoz M, de Las Heras N, Rodríguez Y, García RG, Camacho PA, López-Jaramillo P. Aged garlic extract improves adiponectin levels in subjects with metabolic syndrome: a double-blind, placebo-controlled, randomized, crossover study. Mediators Inflamm. 2013; 2013:285795. PMID: 23533302; PMCID: PMC3603419; DOI: 10.1155/2013/285795;

de las Heras N, Valero-Muñoz M, Ballesteros S, Gómez-Hernández A, Martín-Fernández B, Blanco-Rivero J, Cachofeiro V, Benito M, Balfagón G, Lahera V. Factors involved in rosuvastatin induction of insulin sensitization in rats fed a high fat diet. Nutr Metab Cardiovasc Dis. 2013 Nov; 23(11):1107-14. PMID: 23434394; DOI: 10.1016/j.numecd.2012.11.009;

Valero-Muñoz M, Martín-Fernández B, Ballesteros S, Martínez-Martínez E, Blanco-Rivero J, Balfagón G, Cachofeiro V, Lahera V, de las Heras N. Relevance of vascular peroxisome proliferator-activated receptor ? coactivator-1a to molecular alterations in atherosclerosis. Exp Physiol. 2013 May; 98(5):999-1008. PMID: 23335007; DOI: 10.1113/expphysiol.2012.070557;

Modrego J, de las Heras N, Zamorano-León JJ, Mateos-Cáceres PJ, Martín-Fernández B, Valero-Muñoz M, Lahera V, López-Farré AJ. Changes in cardiac energy metabolic pathways in overweighed rats fed a high-fat diet. Eur J Nutr. 2013 Mar; 52(2):847-56. PMID: 22695689; DOI: 10.1007/s00394-012-0392-7;

Martín-Fernández B, de las Heras N, Miana M, Ballesteros S, Valero-Muñoz M, Vassallo D, Davel AP, Rossoni LV, Cachofeiro V, Lahera V. Spironolactone prevents alterations associated with cardiac hypertrophy produced by isoproterenol in rats: involvement of serum- and glucocorticoid-regulated kinase type 1. Exp Physiol. 2012 Jun; 97(6):710-8. PMID: 22327331; DOI: 10.1113/expphysiol.2011.063230;

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 26 publications over 10 distinct years, with a maximum of 5 publications in 2013 and 2014

Bar chart showing 26 publications over 10 distinct years, with a maximum of 5 publications in 2013 and 2014

Year	Publications
2012	2
2013	5
2014	5
2015	1
2016	4
2017	2
2018	2
2019	1
2020	1
2021	3

In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Heart Failure with Preserved Ejection Fraction
Obesity
Cardiac Hypertrophy
Adipose Tissue

Contact for Mentoring:

617.358.8264

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