Inflammation in human obesity and type 2 diabetes07/01/2016 - 03/31/2018 (Multi-PI)
PI:
Caroline M. Apovian, MDNIH/National Diabetes & Digestive & Kidney Diseases5R01DK108056-02
Pivotal Aspiration Therapy with Adjusted Lifestyle (PATHWAY) Study01/29/2013 - 03/31/2018 (PI)
Aspire Bariatrics, Inc.
A multicenter, randomized, double-blind, placebo-controlled study assessing the occurrence of major adverse cardiovascular events (MACE) in overweight and obese subjects with cardiovascular risk facto07/01/2012 - 06/30/2017 (PI)
Orexigen Therapeutics, Inc.
A Randomized Multi-center pivotal efficacy and safety study comparing the endobarrier gastrointestinal liner system vs. sham for glycemic improvement in inadequately controlled05/15/2013 - 12/31/2016 (PI)
GI Dynamics, Inc.
A Multicenter, Randomized, Double Blind, Placebo Controlled Study Comparing the Safety and Efficacy of Naltrexone Sustained Release (S/R)/Bupropion Sustained Release (S/R) and Placebo in Obese S12/19/2007 - 12/31/2012 (PI)
Orexigen Therapeutics, Inc.
A Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Examine the Efficacy and Safety of Pramlintide+Metreleptin in Obese Subjects Following a Low-Calorie Diet Lead-In01/01/2011 - 06/30/2012 (PI)
Amylin Pharmaceuticals, Inc.
Inspire ME IAA C_00046: International Study of Prediction of Intra-Abdominal Adiposity and its Relationships with CardioMetabolic Risk/Intra-Abdominal Adiposity01/02/2008 - 01/02/2011 (PI)
Sanofi-Aventis, U.S., LLC
A Phase IIB, Multi-Center, Dose-Parallel, Randomized, Double-Blind, Monotherapy and Placebo-Controled Safety and Efficacy Study of Zonisamid SR Alone and Zomisamide SR plus Bupropion SR Combinati07/22/2008 - 07/22/2010 (PI)
Orexigen Therapeutics, Inc.
Improving Family Communication to Reduce Obesity Among Children in Framingham, MA12/31/2005 - 12/30/2008 (Co-PI)
MetroWest Community Health Care Foundation
Self Monitoring of Blood Glucose with Finger Tip Sampling vs. Alternative Site Sampling: Sources of Variability and Effect on Long Term Glycemic Control09/30/2002 - 09/21/2008 (PI)
DHHS OWH
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A Multi-center, Double-blind, Parallel-group, Randomized, Placebo-controlled Study to Evaluate the Efficacy, Safety, and Tolerability of Denagliptin in Subjects with Type 2 Diabetes Mellitus
08/04/2006 - 08/03/2008 (PI)
GlaxoSmithKline, Inc.
A Once-Daily Dose-Ranging Study of GSK189075 Versus Placebo in the Treatment of Type 2 Diabetes Mellitus in Treatment-Naive Subjects
06/05/2007 - 07/30/2008 (PI)
GlaxoSmithKline, Inc.
Effect on Weight Loss of Exenatide Versus Placebo in Subjects with Type 2 Diabetes Participating in a Lifestyle Modification Program
10/27/2006 - 06/30/2008 (PI)
Eli Lilly and Company Amylin Pharm Inc
A Dose of Parallel, Phase 2, Randomized, Placebo-controlled, Multicenter Study of the Safety, Efficacy, and Pharmacokinetics of Multiple Regimens of the Combination of Buproprion SR Plus Zonisamide CR (EXCALIA) in the Treatment of Subjects with Uncomplica
05/17/2006 - 05/16/2008 (PI)
Orexigen Therapeutics, Inc.
A Randomized, Double Blind, Two-Arm Placebo Controlled, 12-month Study of the Effects of Rimonabant 20mg Once Daily on the Amount and the Activity of Visceral Fat in Abdominally Obese Patients with Metabolic Syndrome
03/30/2006 - 03/29/2008 (PI)
Sanofi-Aventis, U.S., LLC
FDA’s Office of Women’s Health Research Studies
09/22/2003 - 09/29/2005 (PI)
HHS/Food and Drug Administration
A Parallel, Six-Month, Double-blind, Randomized, Placebo-Controlled, Multicenter, Dose-Ranging Study to Evaluate the Efficacy, Safety and Tolerability of Orally Administered GI181771X on Weight Loss in Overweight and Obese Subjects
09/23/2003 - 09/23/2005 (PI)
GlaxoSmithKline, Inc.
Three Month Tolerability of Structured Meal Plan Using Meal Replacements and Portion Control to Achieve Healthier Weight in Adolescents
01/01/2003 - 12/31/2004 (PI)
Slim Fast
A 12-Week, Parallel-Group, Double-Blind, Randomized, Placebo-Controlled, Multicenter Study to Evaluate the Efficacy, Safety and Tolerability of GW427353B at 10mg, 25mg, 50mg and 100mg, Administered Orally, Once Daily, as Monotherapy in Subjects With Type
05/12/2004 - 12/20/2004 (PI)
GlaxoSmithKline, Inc.
Reducing Cardiovascular Risk Through Exercise: A Joint COE/CCOE Community Outreach Project
09/30/2002 - 09/29/2003 (PI)
DHHS OWH
Physician Nutrition Specialist Awards
07/01/2000 - 06/30/2002 (PI)
American Society for Clinical Nutrition
The Effect of Combination Therapy of Meridia (subutramine hydrochloride monohydrate) and Meal Replacement on Body Weight and Weight Loss Maintenance in Obese Individuals
08/23/2000 - 01/31/2002 (PI)
Knoll Pharmaceutical Company
A 24-Week Randomized, Double-Blind Study to Evaluate the Efficacy, Safety and Tolerability of Avandia (8mg once daily) in Combination with Glyburide in African American and Hispanic Patients with Type 2 Diabetes Mellitus who are Inadequately Controlled on
08/01/2000 - 08/01/2001 (PI)
SmithKline Beecham
Boston Nutrition Obesity Research Center - Diversity Supplement06/01/2019 - 05/31/2024 (PI)
National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS3P30DK046200-27S2
SELECT - EX9536-4388 - Semaglutide effects on cardiovascular outcomes in people with overweight…11/02/2018 - 08/25/2021 (PI)
Novo Nordisk
ASSESSING FOOD INTAKE WITH THE AUTOMATIC INGESTION MONITOR07/01/2017 - 06/30/2019 (Subcontract PI)
PI:
Caroline M. Apovian, MDTrustees of Boston University,CRC NIH
G-04/GEL3002: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study Assessing…03/31/2016 - 03/31/2019 (PI)
Gelesis, Srl.
GLOW/GS-100-009 EXTENSION02/27/2017 - 02/27/2019 (PI)
Gelesis, Srl.
Inflammation in human obesity and type 2 diabetes10/01/2017 - 03/31/2018 (PI)
University of Kentucky Research Foundation NIH-NIDDKR01DK108056-01
Inflammation in human obesity and type 2 diabetes04/01/2016 - 09/30/2017 (PI)
Trustees of Boston University NIH-NIDDK
Effects of Dietary Composition on Energy Expenditure During Weight-Loss Maintenance10/01/2014 - 07/31/2017 (PI)
Children's Hospital Nutrition Science In
Conversion of Human Muscle Cells to Brown Adipocytes: In Vitro Studies01/01/2017 - 07/19/2017 (PI)
Energesis Pharmaceuticals Dept of Defense
Comparison of Surgical vs. Lifestyle Weight Treatment in Obese Older Adults07/01/2016 - 06/30/2017 (PI)
Beth Israel Center for Nutrition
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Dietary Patterns and Biomarkers of Liver and Kidney Injury02/01/2016 - 01/31/2017 (PI)
Coherence Lab
Optimizing Protein Intake in Older Americans with Mobility Limitations09/01/2013 - 05/31/2016 (PI)
Brigham & Women's NIH-NIA
Apovian - AMPK & Adipose Tissue Biology in Bariatric Surgery Patients07/16/2012 - 06/30/2014 (PI)
NIH-NIDDK1R24 DK094749-01
Optimizing Protein Intake in Older Americans with Mobility Limitations09/15/2010 - 08/31/2013 (Activity-level PI)
PI:
Shalender Bhasin, MBBSNIH-NIA5R01 AG037547-04
Reducing Obesity in Underserved Postpartum African American Women09/01/2010 - 08/31/2013 (PI)
NIH-NICHD1R21 HD061311-01A1
Understanding How Patients Value Bariatric Surgery08/01/2007 - 06/30/2013 (PI)
Beth Israel NIH-NIDDK5R01 DK073302-05
Boston Obesity Center (Pilot)12/01/2006 - 03/31/2013 (PI)
NIH-NIDDK5 P30 DK46200-16
Exercise and Nutrition to Decrease Diabetes01/01/2011 - 12/31/2012 (PI)
AstraZeneca HealthCare Foundation
Effects of the Atkins diet vs. a Low Fat diet on Endothelial function08/21/2008 - 01/31/2011 (PI)
Dr. Robert C. & Veronica Atkins Fdtn
Admin Supplement to - Understanding how patients value bariatric surgery08/01/2009 - 07/31/2010 (PI)
Beth Israel NIH-NIDDK