Caroline M. Apovian, MD
Adjunct Professor
Boston University Chobanian & Avedisian School of Medicine
Endocrinology, Diabetes, Nutrition & Weight Management

MD, University of Medicine and Dentistry of New Jersey
BA, Barnard College

Caroline M. Apovian, MD, FACP, FTOS, DABOM is Adjunct Professor of Medicine and Pediatrics in the Section of Endocrinology, Diabetes, Nutrition and Weight Management at Chobanian and Avedisian School of Medicine, Boston, MA, USA. Until December 2020, she was the Director of the Nutrition and Weight Management Center and the Fellowship Program in Obesity Medicine and Nutrition at Boston Medical Center (BMC). For over thirty years, Dr. Apovian has held a position at the forefront of the obesity and nutrition fields. One of the world’s premier weight loss experts, she has distinguished herself as a leading researcher, healthcare provider, teacher, and New York Times bestselling author.

Under Dr. Apovian’s direction, the Nutrition and Weight Management Center at BMC has specialized in the assessment and treatment of obesity and its comorbidities with a focus on underserved populations, as the Center sees a diverse ethnic population. Nationally, she is one of the founding creators of the American Board of Obesity Medicine which provides certification and recognition for physicians who have specialized knowledge and training in the practice of obesity medicine.

Her current research interests are weight change and its effects on adipose tissue metabolism and inflammation, obesity and cardiovascular disease, resolution of diabetes and cardiovascular disease in the bariatric surgery population, disparities in the treatment of obesity in underserved populations, and novel pharmacotherapeutic agents for the treatment of obesity. She is also an expert in sampling subcutaneous adipose tissue and muscle tissue in humans and has been studying the relationship between adipose tissue inflammation and obesity for over 15 years.

Dr. Apovian has published over ten books and over 200 peer-reviewed original research and review articles on obesity and nutrition. Dr. Apovian was a member of the expert panel for updating the 2013 AHA/ACC/TOS Clinical Guidelines for the Management of Overweight and Obesity in Adults, published in the Circulation and Obesity journals and was the Chair of the Endocrine Society Guidelines for Medical Treatment of Obesity published in the Journal of Endocrinology and Metabolism in 2015. She is a former Nutrition Consultant for the National Aeronautics and Space Administration (NASA). Dr. Apovian has given over 150 invited lectures nationally and internationally and currently serves as Immediate Past-President of The Obesity Society (2017-2018). She has been an active member of The Obesity Society since 1994 and was Secretary/Treasurer from 2005-2009 and President from 2017-2018. She is also Co-Director of the Blackburn Course in Obesity Medicine and Co-Director of the National Institutes of Health (NIH)-sponsored Boston Nutrition and Obesity Research Center (BNORC).

Adjunct Professor
Boston University Chobanian & Avedisian School of Medicine
Diabetes & Endocrinology

Boston University
Evans Center for Interdisciplinary Biomedical Research

Full Member
Boston University Medical Center
Boston Nutrition Obesity Research Center

Graduate Faculty (Primary Mentor of Grad Students)
Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences

Inflammation in human obesity and type 2 diabetes
07/01/2016 - 03/31/2018 (Multi-PI)
PI: Caroline M. Apovian, MD
NIH/National Diabetes & Digestive & Kidney Diseases

Pivotal Aspiration Therapy with Adjusted Lifestyle (PATHWAY) Study
01/29/2013 - 03/31/2018 (PI)
Aspire Bariatrics, Inc.

A multicenter, randomized, double-blind, placebo-controlled study assessing the occurrence of major adverse cardiovascular events (MACE) in overweight and obese subjects with cardiovascular risk facto
07/01/2012 - 06/30/2017 (PI)
Orexigen Therapeutics, Inc.

A Randomized Multi-center pivotal efficacy and safety study comparing the endobarrier gastrointestinal liner system vs. sham for glycemic improvement in inadequately controlled
05/15/2013 - 12/31/2016 (PI)
GI Dynamics, Inc.

A Multicenter, Randomized, Double Blind, Placebo Controlled Study Comparing the Safety and Efficacy of Naltrexone Sustained Release (S/R)/Bupropion Sustained Release (S/R) and Placebo in Obese S
12/19/2007 - 12/31/2012 (PI)
Orexigen Therapeutics, Inc.

A Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Examine the Efficacy and Safety of Pramlintide+Metreleptin in Obese Subjects Following a Low-Calorie Diet Lead-In
01/01/2011 - 06/30/2012 (PI)
Amylin Pharmaceuticals, Inc.

Inspire ME IAA C_00046: International Study of Prediction of Intra-Abdominal Adiposity and its Relationships with CardioMetabolic Risk/Intra-Abdominal Adiposity
01/02/2008 - 01/02/2011 (PI)
Sanofi-Aventis, U.S., LLC

A Phase IIB, Multi-Center, Dose-Parallel, Randomized, Double-Blind, Monotherapy and Placebo-Controled Safety and Efficacy Study of Zonisamid SR Alone and Zomisamide SR plus Bupropion SR Combinati
07/22/2008 - 07/22/2010 (PI)
Orexigen Therapeutics, Inc.

Improving Family Communication to Reduce Obesity Among Children in Framingham, MA
12/31/2005 - 12/30/2008 (Co-PI)
MetroWest Community Health Care Foundation

Self Monitoring of Blood Glucose with Finger Tip Sampling vs. Alternative Site Sampling: Sources of Variability and Effect on Long Term Glycemic Control
09/30/2002 - 09/21/2008 (PI)

Showing 10 of 23 results. Show All Results

Boston Nutrition Obesity Research Center - Diversity Supplement
06/01/2019 - 05/31/2024 (PI)
National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS

SELECT - EX9536-4388 - Semaglutide effects on cardiovascular outcomes in people with overweight…
11/02/2018 - 08/25/2021 (PI)
Novo Nordisk

07/01/2017 - 06/30/2019 (PI)
Trustees of Boston University,CRC National Institutes

G-04/GEL3002: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study Assessing…
03/31/2016 - 03/31/2019 (PI)
Gelesis, Srl.

02/27/2017 - 02/27/2019 (PI)
Gelesis, Srl.

Inflammation in human obesity and type 2 diabetes
10/01/2017 - 03/31/2018 (PI)
University of Kentucky Research Foundation NIH-NIDDK

Inflammation in human obesity and type 2 diabetes
04/01/2016 - 09/30/2017 (PI)
Trustees of Boston University NIH-NIDDK

Effects of Dietary Composition on Energy Expenditure During Weight-Loss Maintenance
10/01/2014 - 07/31/2017 (PI)
Children's Hospital Nutrition Science In

Conversion of Human Muscle Cells to Brown Adipocytes: In Vitro Studies
01/01/2017 - 07/19/2017 (PI)
Energesis Pharmaceuticals Dept of Defense

Comparison of Surgical vs. Lifestyle Weight Treatment in Obese Older Adults
07/01/2016 - 06/30/2017 (PI)
Beth Israel Center for Nutrition

Showing 10 of 20 results. Show All Results


Yr Title Project-Sub Proj Pubs
2020 Boston Nutrition Obesity Research Center 5P30DK046200-28 948
2019 Boston Nutrition Obesity Research Center 5P30DK046200-27 948
2019 Boston Nutrition Obesity Research Center 3P30DK046200-27S1 948
2019 Boston Nutrition Obesity Research Center 3P30DK046200-27S2 948
2019 ConProject-001 3P30DK046200-27S1-6469 948
2019 ConProject-002 3P30DK046200-27S1-6470 948
2019 ConProject-003 3P30DK046200-27S1-6471 948
2019 ConProject-004 3P30DK046200-27S1-6472 948
2018 Boston Nutrition Obesity Research Center 2P30DK046200-26 948
2017 Inflammation in human obesity and type 2 diabetes 5R01DK108056-02 6
Showing 10 of 25 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Paranzino AB, Vieira B, Apovian CM, Agarwal S. Medical Weight Management Considerations in Plastic Surgery. Plast Reconstr Surg. 2024 Apr 02. PMID: 38563562
  2. Medhati P, Saleh OS, Nimeri A, Apovian C, Thompson C, Jirapinyo P, Sheu EG, Tavakkoli A. Outcomes and Management of Re-Establishing Bariatric Patients. J Am Coll Surg. 2024 Jun 01; 238(6):1035-1043. PMID: 38421026
  3. Cho J, Noonan SH, Fay R, Apovian CM, McCarthy AC, Blood AJ, Samal L, Fisher N, Orav JE, Plutzky J, Block JP, Bates DW, Rozenblum R, Tucci M, McPartlin M, Gordon WJ, McManus KD, Morrison-Deutsch C, Scirica BM, Baer HJ. Implementation of a Scalable Online Weight Management Programme in Clinical Settings: Protocol for the PROPS 2.0 Programme (Partnerships for Reducing Overweight and Obesity with Patient-Centered Strategies 2.0). BMJ Open. 2023 Dec 21; 13(12):e077520. PMID: 38135330; PMCID: PMC10748868; DOI: 10.1136/bmjopen-2023-077520;
  4. Apovian CM, Bruno CD, Kyle TK, Chow CR, Greenblatt DJ. Incomplete Data and Potential Risks of Drugs in People with Obesity. Curr Obes Rep. 2023 Dec; 12(4):429-438. PMID: 37980304; PMCID: PMC10748779; DOI: 10.1007/s13679-023-00532-1;
  5. Apovian CM, McDonnell ME. CagriSema and the link between obesity and type 2 diabetes. Lancet. 2023 Aug 26; 402(10403):671-673. PMID: 37364591
  6. Campbell WW, Deutz NEP, Volpi E, Apovian CM. Nutritional Interventions: Dietary Protein Needs and Influences on Skeletal Muscle of Older Adults. J Gerontol A Biol Sci Med Sci. 2023 Jun 16; 78(Supplement_1):67-72. PMID: 37325954; PMCID: PMC10272976; DOI: 10.1093/gerona/glad038;
  7. Velazquez A, Apovian CM. The Effects of Obesity on Health Care Delivery. Gastroenterol Clin North Am. 2023 Jun; 52(2):381-392. PMID: 37197880
  8. Wolfe MM, Apovian CM, Boylan MO. Glucose-dependent insulinotropic polypeptide monoclonal antibodies prevent and treat obesity in wild-type and hyperphagic mice. Obesity (Silver Spring). 2023 Jun; 31(6):1499-1504. PMID: 37203332
  9. Charoenngam N, Apovian CM, Pongchaiyakul C. Increased fat mass negatively influences femoral neck bone mineral density in men but not women. Front Endocrinol (Lausanne). 2023; 14:1035588. PMID: 36926024; PMCID: PMC10011632; DOI: 10.3389/fendo.2023.1035588;
  10. Hafida S, Apovian C. Physiology of the Weight-Reduced State and Its Impact on Weight Regain. Endocrinol Metab Clin North Am. 2022 Dec; 51(4):795-815.View Related Profiles. PMID: 36244694
Showing 10 of 234 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 234 publications over 31 distinct years, with a maximum of 19 publications in 2013 and 2017


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2020 American Board of Obesity Medicine: Distinguished Leader in Obesity Medicine
2018 American Medical Women’s Association: Exceptional Mentor Award
2015 Icahn School of Medicine at Mount Sinai: 4th Annual Mona Shimshi Lectureship
2014 Massachusetts Medical Society Committee on Women in Medicine: Women’s Health Forum 2014 Honor Roll
2014 American Association of Clinical Chemistry: Outstanding Speaker Award for 2014
2000-2002 American Society of Clinic Nutrition: Physician Nutrition Specialist Award
1993-1996 Geisinger Medical Center: Clinician-Investigator Career Development Award
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Adipose tissue
Weight loss and management
Racial disparities
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