Caroline M. Apovian, MD
Professor
Boston University School of Medicine
Dept of Medicine
Endocrinology, Diabetes, Nutrition & Weight Management

MD, University of Medicine and Dentistry of New Jersey




Caroline M. Apovian, MD, FACP, FTOS, DABOM is Professor of Medicine and Pediatrics in the Section of Endocrinology, Diabetes, Nutrition and Weight Management at Boston University School of Medicine, Boston, MA, USA. She is also Director of the Nutrition and Weight Management Center and the Fellowship Program in Obesity Medicine and Nutrition at Boston Medical Center (BMC). For over thirty years, Dr. Apovian has held a position at the forefront of the obesity and nutrition fields. One of the world’s premier weight loss experts, she has distinguished herself as a leading researcher, healthcare provider, teacher, and New York Times bestselling author.

Under Dr. Apovian’s direction, the Nutrition and Weight Management Center at BMC has specialized in the assessment and treatment of obesity and its comorbidities with a focus on underserved populations, as the Center sees a diverse ethnic population. Nationally, she is one of the founding creators of the American Board of Obesity Medicine which provides certification and recognition for physicians who have specialized knowledge and training in the practice of obesity medicine.

Her current research interests are weight change and its effects on adipose tissue metabolism and inflammation, obesity and cardiovascular disease, resolution of diabetes and cardiovascular disease in the bariatric surgery population, disparities in the treatment of obesity in underserved populations, and novel pharmacotherapeutic agents for the treatment of obesity. She is also an expert in sampling subcutaneous adipose tissue and muscle tissue in humans and has been studying the relationship between adipose tissue inflammation and obesity for over 15 years.

Dr. Apovian has published over ten books and over 200 peer-reviewed original research and review articles on obesity and nutrition. Dr. Apovian was a member of the expert panel for updating the 2013 AHA/ACC/TOS Clinical Guidelines for the Management of Overweight and Obesity in Adults, published in the Circulation and Obesity journals and was the Chair of the Endocrine Society Guidelines for Medical Treatment of Obesity published in the Journal of Endocrinology and Metabolism in 2015. She is a former Nutrition Consultant for the National Aeronautics and Space Administration (NASA). Dr. Apovian has given over 150 invited lectures nationally and internationally and currently serves as Immediate Past-President of The Obesity Society (2017-2018). She has been an active member of The Obesity Society since 1994 and was Secretary/Treasurer from 2005-2009 and President from 2017-2018. She is also Co-Director of the Blackburn Course in Obesity Medicine and Co-Director of the National Institutes of Health (NIH)-sponsored Boston Nutrition and Obesity Research Center (BNORC).

Professor
Boston University School of Medicine
Pediatrics
Diabetes & Endocrinology

Member
Boston University
Evans Center for Interdisciplinary Biomedical Research


Full Member
Boston University Medical Center
Boston Nutrition Obesity Research Center


Graduate Faculty (Primary Mentor of Grad Students)
Boston University School of Medicine, Graduate Medical Sciences



2020 American Board of Obesity Medicine: Distinguished Leader in Obesity Medicine
2018 American Medical Women’s Association: Exceptional Mentor Award
2015 Icahn School of Medicine at Mount Sinai: 4th Annual Mona Shimshi Lectureship
2014 Massachusetts Medical Society Committee on Women in Medicine: Women’s Health Forum 2014 Honor Roll
2014 American Association of Clinical Chemistry: Outstanding Speaker Award for 2014
2000-2002 American Society of Clinic Nutrition: Physician Nutrition Specialist Award
1993-1996 Geisinger Medical Center: Clinician-Investigator Career Development Award


Inflammation in human obesity and type 2 diabetes
07/01/2016 - 03/31/2018 (Multi-PI)
PI: Caroline M. Apovian, MD
NIH/National Diabetes & Digestive & Kidney Diseases
5R01DK108056-02

Pivotal Aspiration Therapy with Adjusted Lifestyle (PATHWAY) Study
01/29/2013 - 03/31/2018 (PI)
Aspire Bariatrics, Inc.


A multicenter, randomized, double-blind, placebo-controlled study assessing the occurrence of major adverse cardiovascular events (MACE) in overweight and obese subjects with cardiovascular risk facto
07/01/2012 - 06/30/2017 (PI)
Orexigen Therapeutics, Inc.


A Randomized Multi-center pivotal efficacy and safety study comparing the endobarrier gastrointestinal liner system vs. sham for glycemic improvement in inadequately controlled
05/15/2013 - 12/31/2016 (PI)
GI Dynamics, Inc.


A Multicenter, Randomized, Double Blind, Placebo Controlled Study Comparing the Safety and Efficacy of Naltrexone Sustained Release (S/R)/Bupropion Sustained Release (S/R) and Placebo in Obese S
12/19/2007 - 12/31/2012 (PI)
Orexigen Therapeutics, Inc.


A Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Examine the Efficacy and Safety of Pramlintide+Metreleptin in Obese Subjects Following a Low-Calorie Diet Lead-In
01/01/2011 - 06/30/2012 (PI)
Amylin Pharmaceuticals, Inc.


Inspire ME IAA C_00046: International Study of Prediction of Intra-Abdominal Adiposity and its Relationships with CardioMetabolic Risk/Intra-Abdominal Adiposity
01/02/2008 - 01/02/2011 (PI)
Sanofi-Aventis, U.S., LLC


A Phase IIB, Multi-Center, Dose-Parallel, Randomized, Double-Blind, Monotherapy and Placebo-Controled Safety and Efficacy Study of Zonisamid SR Alone and Zomisamide SR plus Bupropion SR Combinati
07/22/2008 - 07/22/2010 (PI)
Orexigen Therapeutics, Inc.


Improving Family Communication to Reduce Obesity Among Children in Framingham, MA
12/31/2005 - 12/30/2008 (Co-PI)
MetroWest Community Health Care Foundation

Self Monitoring of Blood Glucose with Finger Tip Sampling vs. Alternative Site Sampling: Sources of Variability and Effect on Long Term Glycemic Control
09/30/2002 - 09/21/2008 (PI)
DHHS OWH

Showing 10 of 23 results. Show All Results

Boston Nutrition Obesity Research Center - Diversity Supplement
06/01/2019 - 05/31/2022 (PI)
NIH-NIDDK
3P30DK046200-27S2

Boston Nutrition Obesity Research Center (Pilot)
06/01/2018 - 05/31/2022 (PI)
NIH-NIDDK
5P30DK046200-27

Boston Nutrition Obesity Research Center(Ac)
06/01/2018 - 05/31/2022 (PI)
NIH-NIDDK
2P30DK046200-26

Boston Nutrition Obesity Research Center(Administrative Core)
06/01/2018 - 05/31/2022 (PI)
NIH-NIDDK
5P30DK046200-27

Boston nutrition Obesity Research Center(CCRC/Epid/Tc)
06/01/2018 - 05/31/2022 (PI)
NIH-NIDDK
5P30DK046200-27

Boston Nutrition Obesity Research Center
06/01/2018 - 05/31/2022 (PI)
NIH-NIDDK
3P30DK046200-27S1

Boston Nutrition Obesity Research Center
06/01/2018 - 05/31/2022 (PI)
NIH-NIDDK
3P30DK046200-27S2

SELECT - EX9536-4388 - Semaglutide effects on cardiovascular outcomes in people with overweight…
11/02/2018 - 11/02/2021 (PI)
Novo Nordisk

Boston Nutrition Obesity Research Center - Administrative Supplement
06/01/2019 - 05/31/2020 (PI)
NIH-NIDDK
3P30DK046200-27S1

Assessing Food Intake with the Automatic Ingestion Monitor
07/01/2017 - 06/30/2019 (PI)
Trustees of Boston University NIH-NIDDK

Showing 10 of 27 results. Show All Results

Title


Yr Title Project-Sub Proj Pubs
2020 Boston Nutrition Obesity Research Center 5P30DK046200-28 948
2019 Boston Nutrition Obesity Research Center 5P30DK046200-27 948
2019 Boston Nutrition Obesity Research Center 3P30DK046200-27S1 948
2019 Boston Nutrition Obesity Research Center 3P30DK046200-27S2 948
2019 ConProject-001 3P30DK046200-27S1-6469 948
2019 ConProject-002 3P30DK046200-27S1-6470 948
2019 ConProject-003 3P30DK046200-27S1-6471 948
2019 ConProject-004 3P30DK046200-27S1-6472 948
2017 Inflammation in human obesity and type 2 diabetes 5R01DK108056-02 6
2016 Inflammation in human obesity and type 2 diabetes 1R01DK108056-01A1 6
Showing 10 of 24 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Istfan NW, Anderson WA, Hess DT, Yu L, Carmine B, Apovian CM. The Mitigating Effect of Phentermine and Topiramate on Weight Regain After Roux-en-Y Gastric Bypass Surgery. Obesity (Silver Spring). 2020 06; 28(6):1023-1030.View Related Profiles. PMID: 32441476
     
  2. Bharath LP, Agrawal M, McCambridge G, Nicholas DA, Hasturk H, Liu J, Jiang K, Liu R, Guo Z, Deeney J, Apovian CM, Snyder-Cappione J, Hawk GS, Fleeman RM, Pihl RMF, Thompson K, Belkina AC, Cui L, Proctor EA, Kern PA, Nikolajczyk BS. Metformin Enhances Autophagy and Normalizes Mitochondrial Function to Alleviate Aging-Associated Inflammation. Cell Metab. 2020 Jul 07; 32(1):44-55.e6.View Related Profiles. PMID: 32402267
     
  3. Coleman KJ, Schlundt DG, Bonnet KR, Holmquist KJ, Dunne J, Crull E, Hanaoka BY, Lent MR, Nadglowski J, Sylvia L, Venkatachalam S, Xanthakos SA, Zeiger R, Arterburn D, Williams N, Courcoulas A, Anau J, McTigue KM, Blalock C, Malanga E, McClay J, McBride CL, Schlundt D, Emiliano A, Nemr R, McTigue K, Courcoulas A, Xanthakos SA, Michalsky M, Coleman KJ, Murali S, Tavakkoli A, Desai N, Apovian C, Clark J, Nauman E, Cirielli E, Nadglowski J, St Clair T, Tice J, Vitello J, Zeiger R, Arterburn D, Anau J, Janning C, Williams N. Understanding the Bariatric Patient Perspective in the National Patient-Centered Clinical Research Network (PCORnet) Bariatric Study. Obes Surg. 2020 May; 30(5):1837-1847. PMID: 31965490
     
  4. Mechanick JI, Apovian C, Brethauer S, Timothy Garvey W, Joffe AM, Kim J, Kushner RF, Lindquist R, Pessah-Pollack R, Seger J, Urman RD, Adams S, Cleek JB, Correa R, Figaro MK, Flanders K, Grams J, Hurley DL, Kothari S, Seger MV, Still CD. Clinical Practice Guidelines for the Perioperative Nutrition, Metabolic, and Nonsurgical Support of Patients Undergoing Bariatric Procedures - 2019 Update: Cosponsored by American Association of Clinical Endocrinologists/American College of Endocrinology, The Obesity Society, American Society for Metabolic and Bariatric Surgery, Obesity Medicine Association, and American Society of Anesthesiologists. Obesity (Silver Spring). 2020 Apr; 28(4):O1-O58. PMID: 32202076
     
  5. Rubino F, Puhl RM, Cummings DE, Eckel RH, Ryan DH, Mechanick JI, Nadglowski J, Ramos Salas X, Schauer PR, Twenefour D, Apovian CM, Aronne LJ, Batterham RL, Berthoud HR, Boza C, Busetto L, Dicker D, De Groot M, Eisenberg D, Flint SW, Huang TT, Kaplan LM, Kirwan JP, Korner J, Kyle TK, Laferrère B, le Roux CW, McIver L, Mingrone G, Nece P, Reid TJ, Rogers AM, Rosenbaum M, Seeley RJ, Torres AJ, Dixon JB. Joint international consensus statement for ending stigma of obesity. Nat Med. 2020 04; 26(4):485-497. PMID: 32127716
     
  6. Jafarzadeh SR, Neogi T, Stefanik JJ, Li JS, Guermazi A, Apovian CM, Felson DT. Mediating Role of Bone Marrow Lesions, Synovitis, Pain Sensitization, and Depressive Symptoms on Knee Pain Improvement Following Substantial Weight Loss. Arthritis Rheumatol. 2020 03; 72(3):420-427.View Related Profiles. PMID: 31562683
     
  7. Thomas DD, Stockman MC, Yu L, Meshulam T, McCarthy AC, Ionson A, Burritt N, Deeney J, Cabral H, Corkey B, Istfan N, Apovian CM. Effects of medium chain triglycerides supplementation on insulin sensitivity and beta cell function: A feasibility study. PLoS One. 2019; 14(12):e0226200.View Related Profiles. PMID: 31869355
     
  8. Mechanick JI, Apovian C, Brethauer S, Garvey WT, Joffe AM, Kim J, Kushner RF, Lindquist R, Pessah-Pollack R, Seger J, Urman RD, Adams S, Cleek JB, Correa R, Figaro MK, Flanders K, Grams J, Hurley DL, Kothari S, Seger MV, Still CD. CLINICAL PRACTICE GUIDELINES FOR THE PERIOPERATIVE NUTRITION, METABOLIC, AND NONSURGICAL SUPPORT OF PATIENTS UNDERGOING BARIATRIC PROCEDURES - 2019 UPDATE: COSPONSORED BY AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS/AMERICAN COLLEGE OF ENDOCRINOLOGY, THE OBESITY SOCIETY, AMERICAN SOCIETY FOR METABOLIC & BARIATRIC SURGERY, OBESITY MEDICINE ASSOCIATION, AND AMERICAN SOCIETY OF ANESTHESIOLOGISTS - EXECUTIVE SUMMARY. Endocr Pract. 2019 Dec; 25(12):1346-1359. PMID: 31682518
     
  9. Mechanick JI, Apovian C, Brethauer S, Garvey WT, Joffe AM, Kim J, Kushner RF, Lindquist R, Pessah-Pollack R, Seger J, Urman RD, Adams S, Cleek JB, Correa R, Figaro MK, Flanders K, Grams J, Hurley DL, Kothari S, Seger MV, Still CD. Clinical practice guidelines for the perioperative nutrition, metabolic, and nonsurgical support of patients undergoing bariatric procedures - 2019 update: cosponsored by American Association of Clinical Endocrinologists/American College of Endocrinology, The Obesity Society, American Society for Metabolic & Bariatric Surgery, Obesity Medicine Association, and American Society of Anesthesiologists. Surg Obes Relat Dis. 2020 Feb; 16(2):175-247. PMID: 31917200
     
  10. Srivastava G, Apovian CM. Clinical Challenge: Patient With Severe Obesity BMI 46 kg/m2. Front Endocrinol (Lausanne). 2019; 10:635. PMID: 31632343
     
Showing 10 of 198 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 198 publications over 27 distinct years, with a maximum of 19 publications in 2013 and 2017

YearPublications
19881
19903
19921
19951
19962
19972
19991
20011
20023
20031
20043
20057
20062
20076
200814
200912
201011
20118
201211
201319
201412
201511
201612
201719
201812
201917
20206


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In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Adipose tissue
Diabetes
Inflammation
Nutrition
Obesity
Weight loss and management
Racial disparities
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