Serkalem Demissie, PhD
Research Professor
Boston University School of Public Health

PhD, Boston University
MPH, Boston University
BSc, Addis Ababa University

Serkalem Demissie, Ph.D., is Research Professor in the Department of Biostatistics. Serkalem has over 20 years of statistical and computing experience. Professor Demissie’s expertise is in the development, evaluation, and application of statistical methods, with emphasis on statistical genetics and estimation and evaluation of exposure-outcome associations. A major part of her scholarly work is linked to long-standing collaborations in the Framingham Heart Study (FHS) in the fields of cardiovascular disease, lipids, musculoskeletal phenotypes, and neurological disorders. Her work in statistical methodologies includes missing data, residual phenotype modeling in genetic and epidemiologic studies, multiple testing, temporal gene expression data clustering, and measuring biological age.

Framingham Heart Study

Boston University
Genome Science Institute

Population subgroup difference in aging trajectory and health: Methods and application
09/10/2020 - 05/31/2024 (PI)
NIH/National Institute on Aging

Contract to support the Division of Population Health and Data Science at the Massachusetts Veterans Epidemiology Research and Informatics Center (MAVERIC)
09/30/2020 - 09/29/2021 (PI of Sub-Project / SP)
PI: David R. Gagnon, MD, PhD
VA Boston Healthcare System

VA241-17-D-0092 VA Master Contract Task Order 7
12/22/2018 - 12/21/2019 (PI of Sub-Project / SP)
PI: Steven D. Pizer, PhD
VA Boston Healthcare System

Biomechanics of Vertebral Fractures: The Framingham QCT Study
09/01/2016 - 08/31/2018 (Subcontract PI)
Beth Israel Deaconess Medical Center, Inc NIH NIAMS

Bone Microarchitecture: The Framingham Osteoporosis Study
05/01/2012 - 04/30/2018 (Subcontract PI)
Hebrew Rehabilitation Center NIH NIAMS

Biomechanics of Vertebral Fractures: The Framingham QCT Study
09/18/2013 - 08/31/2017 (Subcontract PI)
Beth Israel Deaconess Medical Center, Inc NIH NIAMS

Biomechanics of Vertebral Fractures: The Framingham QCT Study
08/01/2011 - 07/31/2012 (Subcontract PI)
Beth Israel Deaconess Medical Center, Inc NIH NIAMS


Yr Title Project-Sub Proj Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. Ekenze O, Pinheiro A, Demissie S, Charidimou A, Beiser AS, Vasan RS, Benjamin EJ, DeCarli C, Seshadri S, Romero JR. Inflammatory biomarkers and MRI visible perivascular spaces: The Framingham Heart Study. Neurobiol Aging. 2023 Jul; 127:12-22.View Related Profiles. PMID: 37018882; PMCID: PMC10198814; DOI: 10.1016/j.neurobiolaging.2023.03.001;
  2. Hussein AI, Carroll D, Bui M, Wolff A, Matheny H, Hogue B, Lybrand K, Cooke M, Bragdon B, Morgan E, Demissie S, Gerstenfeld L. Oxidative metabolism is impaired by phosphate deficiency during fracture healing and is mechanistically related to BMP induced chondrocyte differentiation. Bone Rep. 2023 Jun; 18:101657.View Related Profiles. PMID: 37425193; PMCID: PMC10323218; DOI: 10.1016/j.bonr.2023.101657;
  3. Joseph J, Liu C, Hui Q, Aragam K, Wang Z, Charest B, Huffman JE, Keaton JM, Edwards TL, Demissie S, Djousse L, Casas JP, Gaziano JM, Cho K, Wilson PWF, Phillips LS, O'Donnell CJ, Sun YV. Genetic architecture of heart failure with preserved versus reduced ejection fraction. Nat Commun. 2022 Dec 14; 13(1):7753.View Related Profiles. PMID: 36517512; PMCID: PMC9751124; DOI: 10.1038/s41467-022-35323-0;
  4. Baril AA, Pinheiro AA, Himali JJ, Beiser A, Sanchez E, Pase MP, Seshadri S, Demissie S, Romero JR. Lighter sleep is associated with higher enlarged perivascular spaces burden in middle-aged and elderly individuals. Sleep Med. 2022 Dec; 100:558-564.View Related Profiles. PMID: 36308914; PMCID: PMC9815141; DOI: 10.1016/j.sleep.2022.10.006;
  5. Romero JR, Pinheiro A, Aparicio HJ, DeCarli CS, Demissie S, Seshadri S. MRI Visible Perivascular Spaces and Risk of Incident Dementia: The Framingham Heart Study. Neurology. 2022 Sep 29; 99(23):e2561-71.View Related Profiles. PMID: 36175148; PMCID: PMC9754649; DOI: 10.1212/WNL.0000000000201293;
  6. Lara FR, Scruton AL, Pinheiro A, Demissie S, Parva P, Charidimou A, Francis M, Himali JJ, DeCarli C, Beiser A, Seshadri S, Romero JR. Aging, prevalence and risk factors of MRI-visible enlarged perivascular spaces. Aging (Albany NY). 2022 Jul 15; 14(17):6844-6858.View Related Profiles. PMID: 35852852; PMCID: PMC9512514; DOI: 10.18632/aging.204181;
  7. do Valle IF, Ferolito B, Gerlovin H, Costa L, Demissie S, Linares F, Cohen J, Gagnon DR, Gaziano JM, Begoli E, Cho K, Barabási AL. Network-medicine framework for studying disease trajectories in U.S. veterans. Sci Rep. 2022 Jul 14; 12(1):12018.View Related Profiles. PMID: 35835798; PMCID: PMC9283486; DOI: 10.1038/s41598-022-15764-9;
  8. Pinheiro A, Demissie S, Scruton A, Charidimou A, Parva P, DeCarli C, Seshadri S, Romero JR. Association of Apolipoprotein E ?4 Allele with Enlarged Perivascular Spaces. Ann Neurol. 2022 Jul; 92(1):23-31.View Related Profiles. PMID: 35373386; PMCID: PMC9233108; DOI: 10.1002/ana.26364;
  9. Peeri NC, Tao MH, Demissie S, Nguyen UDT. Sleep Duration, Chronotype, and Insomnia and the Risk of Lung Cancer: United Kingdom Biobank Cohort. Cancer Epidemiol Biomarkers Prev. 2022 Apr 01; 31(4):766-774. PMID: 35086821
  10. Lu D, Demissie S, Horowitz NB, Gower AC, Lenburg ME, Alekseyev YO, Hussein AI, Bragdon B, Liu Y, Daukss D, Page JM, Webster MZ, Schlezinger JJ, Morgan EF, Gerstenfeld LC. Temporal and Quantitative Transcriptomic Differences Define Sexual Dimorphism in Murine Postnatal Bone Aging. JBMR Plus. 2022 Feb; 6(2):e10579.View Related Profiles. PMID: 35229061; PMCID: PMC8861981; DOI: 10.1002/jbm4.10579;
Showing 10 of 149 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 149 publications over 25 distinct years, with a maximum of 14 publications in 2010


Contact for Mentoring:

801 Massachusetts Ave Crosstown Center
Boston MA 02118
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