Serkalem Demissie | Profiles RNS

Serkalem Demissie, PhD

Adjunct Research Professor

Boston University School of Public Health

Biostatistics

PhD, Boston University
MPH, Boston University
BSc, Addis Ababa University

Websites

School of Public Health Faculty

ORCID : 0000-0002-8009-0987

Serkalem Demissie, Ph.D., is an adjunct research professor in the Department of Biostatistics. Serkalem has over 20 years of statistical and computing experience. Professor Demissie’s expertise is in the development, evaluation, and application of statistical methods, with emphasis on statistical genetics and estimation and evaluation of exposure-outcome associations. A major part of her scholarly work is linked to long-standing collaborations in the Framingham Heart Study (FHS) in the fields of cardiovascular disease, lipids, musculoskeletal phenotypes, and neurological disorders. Her work in statistical methodologies includes missing data, residual phenotype modeling in genetic and epidemiologic studies, multiple testing, temporal gene expression data clustering, and measuring biological age.

Investigator
Framingham Heart Study

Member
Boston University
Genome Science Institute

BU Research

Population subgroup difference in aging trajectory and health: Methods and application
09/10/2020 - 05/31/2024 (PI)
NIH/National Institute on Aging
5R21AG068772-02

Contract to support the Division of Population Health and Data Science at the Massachusetts Veterans Epidemiology Research and Informatics Center (MAVERIC)
09/30/2020 - 09/29/2021 (PI of Sub-Project / SP)
PI: David R. Gagnon, MD, PhD
VA Boston Healthcare System

VA241-17-D-0092 VA Master Contract Task Order 7
12/22/2018 - 12/21/2019 (PI of Sub-Project / SP)
PI: Steven D. Pizer, PhD
VA Boston Healthcare System

Biomechanics of Vertebral Fractures: The Framingham QCT Study
09/01/2016 - 08/31/2018 (Subcontract PI)
Beth Israel Deaconess Medical Center, Inc. NIH NIAMS
4R01AR053986-09

Bone Microarchitecture: The Framingham Osteoporosis Study
05/01/2012 - 04/30/2018 (Subcontract PI)
Hebrew Rehabilitation Center NIH NIAMS
R01AR061455-05

Biomechanics of Vertebral Fractures: The Framingham QCT Study
09/18/2013 - 08/31/2017 (Subcontract PI)
Beth Israel Deaconess Medical Center, Inc. NIH NIAMS
5R01AR053986-09

Biomechanics of Vertebral Fractures: The Framingham QCT Study
08/01/2011 - 07/31/2012 (Subcontract PI)
Beth Israel Deaconess Medical Center, Inc. NIH NIAMS
5R01AR053986-05

Title

Yr	Title	Project-Sub Proj	Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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Toro A, Lara FR, Pinheiro A, Demissie S, DeCarli C, Parva P, Habes M, Charidimou A, Seshadri S, Maillard P, Romero JR. Association of MRI-Visible Perivascular Spaces with Early White Matter Injury. AJNR Am J Neuroradiol. 2025 Oct 01; 46(10):2018-2025.View Related Profiles.

Romero, Jose
Parva, Pedram
Demissie, Serkalem
Seshadri, Sudha

PMID: 40461258

Pinheiro A, Ekenze O, Aparicio HJ, Beiser AS, Decarli CS, Demissie S, Seshadri S, Romero JR. Multimarker Cerebral Small Vessel Disease Score and Risk of Incident Dementia in the Framingham Heart Study. Neurology. 2025 Oct 07; 105(7):e214113.View Related Profiles.

Beiser, Alexa
Aparicio, Hugo
Romero, Jose
Ekenze, Oluchi
Demissie, Serkalem
Seshadri, Sudha

PMID: 40953349; PMCID: PMC12443037; DOI: 10.1212/WNL.0000000000214113;

Araujo-Contreras R, Pinheiro AA, Ekenze O, Sisto J, Aparicio HJ, Beiser A, Himali JJ, Lioutas V, DeCarli C, Seshadri S, Demissie S, Romero JR. Multi-marker cerebral small vessel disease score and risk of incident depression: The Framingham Heart Study. J Affect Disord. 2026 Jan 01; 392:120089.View Related Profiles.

Beiser, Alexa
Aparicio, Hugo
Himali, Jayandra
Romero, Jose
Ekenze, Oluchi
Demissie, Serkalem
Seshadri, Sudha

PMID: 40848767; DOI: 10.1016/j.jad.2025.120089;

Ekenze O, Pinheiro A, Beiser AS, Lioutas VA, Aparicio HJ, Benjamin EJ, Vasan RS, DeCarli C, Seshadri S, Demissie S, Romero JR. Prevalent Cardiovascular Disease and Atrial Fibrillation in Relation to Cerebral Small Vessel Disease Burden. Brain Sci. 2025 Jul 29; 15(8).View Related Profiles.

Beiser, Alexa
Benjamin, Emelia
Aparicio, Hugo
Romero, Jose
Ekenze, Oluchi
Demissie, Serkalem
Seshadri, Sudha

PMID: 40867146; PMCID: PMC12385141; DOI: 10.3390/brainsci15080813;

Ekenze O, Seiler S, Pinheiro A, DeCarli C, Parva P, Habes M, Charidimou A, Maillard P, Beiser A, Seshadri S, Demissie S, Romero JR. Relation of MRI visible perivascular spaces with global and regional brain structural connectivity measures: The Framingham Heart Study (FHS). Neurobiol Aging. 2025 Jun; 150:1-8.View Related Profiles.

Beiser, Alexa
Romero, Jose
Ekenze, Oluchi
Parva, Pedram
Demissie, Serkalem
Seshadri, Sudha

PMID: 40043467; PMCID: PMC11981825; DOI: 10.1016/j.neurobiolaging.2025.02.007;

Pinheiro A, Aparicio H, Lioutas V, Beiser A, Ekenze O, DeCarli C, Seshadri S, Demissie S, Romero JR. Higher burden of cerebral small vessel disease is associated with risk of incident stroke in community dwelling individuals. medRxiv. 2024 Nov 15.View Related Profiles.

Beiser, Alexa
Aparicio, Hugo
Ekenze, Oluchi
Demissie, Serkalem
Seshadri, Sudha

PMID: 39606408; PMCID: PMC11601694; DOI: 10.1101/2024.11.13.24317296;

Kelly DM, Pinheiro AA, Koini M, Anderson CD, Aparicio H, Hofer E, Kern D, Blacker D, DeCarli C, Hwang SJ, Viswanathan A, Gonzales MM, Beiser AS, Seshadri S, Schmidt R, Demissie S, Romero JR. Impaired kidney function, cerebral small vessel disease and cognitive disorders: the Framingham Heart Study. Nephrol Dial Transplant. 2024 Oct 30; 39(11):1911-1922.View Related Profiles.

Beiser, Alexa
Aparicio, Hugo
Romero, Jose
Demissie, Serkalem
Hwang, Shih-Jen
Seshadri, Sudha

PMID: 38565317; PMCID: PMC11522878; DOI: 10.1093/ndt/gfae079;

Petrea RE, Pinheiro A, Demissie S, Ekenze O, Aparicio HJ, Satizabal CL, Maillard P, DeCarli C, Beiser AS, Seshadri S, Lioutas VA, Rafael Romero J. Hypertension Trends and White Matter Brain Injury in the Offspring Framingham Heart Study Cohort. Hypertension. 2024 Jan; 81(1):87-95.View Related Profiles.

Beiser, Alexa
Satizabal, Claudia
Aparicio, Hugo
Ekenze, Oluchi
Petrea, Rodica
Demissie, Serkalem
Seshadri, Sudha

PMID: 37855140; PMCID: PMC10896002; DOI: 10.1161/HYPERTENSIONAHA.123.21264;

Rodriguez Lara F, Toro AR, Pinheiro A, Demissie S, Ekenze O, Martinez O, Parva P, Charidimou A, Ghosh S, DeCarli C, Seshadri S, Habes M, Maillard P, Romero JR. Relation of MRI-Visible Perivascular Spaces and Other MRI Markers of Cerebral Small Vessel Disease. Brain Sci. 2023 Sep 14; 13(9).View Related Profiles.

Charidimou , Antreas
Romero, Jose
Ekenze, Oluchi
Parva, Pedram
Demissie, Serkalem
Seshadri, Sudha

PMID: 37759924; PMCID: PMC10527297; DOI: 10.3390/brainsci13091323;

Ekenze O, Pinheiro A, Demissie S, Charidimou A, Beiser AS, Vasan RS, Benjamin EJ, DeCarli C, Seshadri S, Romero JR. Inflammatory biomarkers and MRI visible perivascular spaces: The Framingham Heart Study. Neurobiol Aging. 2023 Jul; 127:12-22.View Related Profiles.

Beiser, Alexa
Charidimou , Antreas
Benjamin, Emelia
Romero, Jose
Ekenze, Oluchi
Demissie, Serkalem
Seshadri, Sudha

PMID: 37018882; PMCID: PMC10198814; DOI: 10.1016/j.neurobiolaging.2023.03.001;

Showing 10 of 160 results. Show More

Hussein AI, Carroll D, Bui M, Wolff A, Matheny H, Hogue B, Lybrand K, Cooke M, Bragdon B, Morgan E, Demissie S, Gerstenfeld L. Oxidative metabolism is impaired by phosphate deficiency during fracture healing and is mechanistically related to BMP induced chondrocyte differentiation. Bone Rep. 2023 Jun; 18:101657.View Related Profiles.

Hussein, Amira
Bragdon, Beth
Morgan, Elise
Gerstenfeld, Louis
Demissie, Serkalem

PMID: 37425193; PMCID: PMC10323218; DOI: 10.1016/j.bonr.2023.101657;

Ekenze O, Pinheiro A, Demissie S, Aparicio HJ, Charidimou A, Beiser AS, Satizabal CL, Kautz T, DeCarli C, Greenberg S, Seshadri S, Romero JR. Association of MRI Visible Perivascular Spaces and Neurofilament Light Chain: The Framingham Heart Study. J Alzheimers Dis. 2023; 95(3):1133-1145.View Related Profiles.

Beiser, Alexa
Charidimou , Antreas
Satizabal, Claudia
Aparicio, Hugo
Romero, Jose
Ekenze, Oluchi
Demissie, Serkalem
Seshadri, Sudha

PMID: 37661877; PMCID: PMC11298784; DOI: 10.3233/JAD-221260;

Pase MP, Pinheiro A, Rowsthorn E, Demissie S, Hurmez S, Aparicio HJ, Rodriguez-Lara F, Gonzales MM, Beiser A, DeCarli C, Seshadri S, Romero JR. MRI Visible Perivascular Spaces and the Risk of Incident Mild Cognitive Impairment in a Community Sample. J Alzheimers Dis. 2023; 96(1):103-112.View Related Profiles.

Beiser, Alexa
Aparicio, Hugo
Romero, Jose
Demissie, Serkalem
Seshadri, Sudha

PMID: 37742645; PMCID: PMC10846532; DOI: 10.3233/JAD-230445;

Joseph J, Liu C, Hui Q, Aragam K, Wang Z, Charest B, Huffman JE, Keaton JM, Edwards TL, Demissie S, Djousse L, Casas JP, Gaziano JM, Cho K, Wilson PWF, Phillips LS, O'Donnell CJ, Sun YV. Genetic architecture of heart failure with preserved versus reduced ejection fraction. Nat Commun. 2022 Dec 14; 13(1):7753.View Related Profiles.

O'Donnell, Christopher
Gaziano, J. Michael
Joseph, Jacob
Demissie, Serkalem

PMID: 36517512; PMCID: PMC9751124; DOI: 10.1038/s41467-022-35323-0;

Romero JR, Pinheiro A, Aparicio HJ, DeCarli CS, Demissie S, Seshadri S. MRI-Visible Perivascular Spaces and Risk of Incident Dementia: The Framingham Heart Study. Neurology. 2022 Dec 05; 99(23):e2561-e2571.View Related Profiles.

Aparicio, Hugo
Romero, Jose
Demissie, Serkalem
Seshadri, Sudha

PMID: 36175148; PMCID: PMC9754649; DOI: 10.1212/WNL.0000000000201293;

Baril AA, Pinheiro AA, Himali JJ, Beiser A, Sanchez E, Pase MP, Seshadri S, Demissie S, Romero JR. Lighter sleep is associated with higher enlarged perivascular spaces burden in middle-aged and elderly individuals. Sleep Med. 2022 Dec; 100:558-564.View Related Profiles.

Beiser, Alexa
Himali, Jayandra
Romero, Jose
Demissie, Serkalem
Seshadri, Sudha

PMID: 36308914; PMCID: PMC9815141; DOI: 10.1016/j.sleep.2022.10.006;

Lara FR, Scruton AL, Pinheiro A, Demissie S, Parva P, Charidimou A, Francis M, Himali JJ, DeCarli C, Beiser A, Seshadri S, Romero JR. Aging, prevalence and risk factors of MRI-visible enlarged perivascular spaces. Aging (Albany NY). 2022 Jul 15; 14(17):6844-6858.View Related Profiles.

Beiser, Alexa
Charidimou , Antreas
Himali, Jayandra
Romero, Jose
Parva, Pedram
Demissie, Serkalem
Seshadri, Sudha

PMID: 35852852; PMCID: PMC9512514; DOI: 10.18632/aging.204181;

do Valle IF, Ferolito B, Gerlovin H, Costa L, Demissie S, Linares F, Cohen J, Gagnon DR, Gaziano JM, Begoli E, Cho K, Barabási AL. Network-medicine framework for studying disease trajectories in U.S. veterans. Sci Rep. 2022 Jul 14; 12(1):12018.View Related Profiles.

Gagnon, David
Gerlovin, Hanna
Gaziano, J. Michael
Demissie, Serkalem

PMID: 35835798; PMCID: PMC9283486; DOI: 10.1038/s41598-022-15764-9;

Pinheiro A, Demissie S, Scruton A, Charidimou A, Parva P, DeCarli C, Seshadri S, Romero JR. Association of Apolipoprotein E ?4 Allele with Enlarged Perivascular Spaces. Ann Neurol. 2022 Jul; 92(1):23-31.View Related Profiles.

Charidimou , Antreas
Romero, Jose
Parva, Pedram
Demissie, Serkalem
Seshadri, Sudha

PMID: 35373386; PMCID: PMC9233108; DOI: 10.1002/ana.26364;

Peeri NC, Tao MH, Demissie S, Nguyen UDT. Sleep Duration, Chronotype, and Insomnia and the Risk of Lung Cancer: United Kingdom Biobank Cohort. Cancer Epidemiol Biomarkers Prev. 2022 Apr 01; 31(4):766-774. PMID: 35086821

Lu D, Demissie S, Horowitz NB, Gower AC, Lenburg ME, Alekseyev YO, Hussein AI, Bragdon B, Liu Y, Daukss D, Page JM, Webster MZ, Schlezinger JJ, Morgan EF, Gerstenfeld LC. Temporal and Quantitative Transcriptomic Differences Define Sexual Dimorphism in Murine Postnatal Bone Aging. JBMR Plus. 2022 Feb; 6(2):e10579.View Related Profiles.

Gower, Adam
Hussein, Amira
Bragdon, Beth
Morgan, Elise
Schlezinger, Jennifer
Gerstenfeld, Louis
Lenburg, Marc
Demissie, Serkalem
Alekseyev, Yuriy

PMID: 35229061; PMCID: PMC8861981; DOI: 10.1002/jbm4.10579;

Aparicio HJ, Tarko LM, Gagnon D, Costa L, Galloway A, Demissie S, Djousse L, Seshadri S, Cho K, Wilson PWF. Low Blood Pressure, Comorbidities, and Ischemic Stroke Mortality in US Veterans. Stroke. 2022 03; 53(3):886-894.View Related Profiles.

Gagnon, David
Aparicio, Hugo
Demissie, Serkalem
Seshadri, Sudha

PMID: 34727740; PMCID: PMC8885902; DOI: 10.1161/STROKEAHA.120.033195;

Romero JR, Demissie S, Beiser A, Himali JJ, DeCarli C, Levy D, Seshadri S. Relation of plasma ß-amyloid, clusterin, and tau with cerebral microbleeds: Framingham Heart Study. Ann Clin Transl Neurol. 2020 07; 7(7):1083-1091.View Related Profiles.

Beiser, Alexa
Levy, Daniel
Himali, Jayandra
Romero, Jose
Demissie, Serkalem
Seshadri, Sudha

PMID: 32588552; PMCID: PMC7359126; DOI: 10.1002/acn3.51066;

Baradaran H, Demissie S, Himali JJ, Beiser A, Gupta A, Polak JF, DeCarli C, Seshadri S, Romero JR. The progression of carotid atherosclerosis and imaging markers of dementia. Alzheimers Dement (N Y). 2020; 6(1):e12015.View Related Profiles.

Beiser, Alexa
Himali, Jayandra
Romero, Jose
Polak, Joseph
Demissie, Serkalem
Seshadri, Sudha

PMID: 32296732; PMCID: PMC7154591; DOI: 10.1002/trc2.12015;

Kaiser J, Allaire B, Fein PM, Lu D, Adams A, Kiel DP, Jarraya M, Guermazi A, Demissie S, Samelson EJ, Bouxsein ML, Morgan EF. Heterogeneity and Spatial Distribution of Intravertebral Trabecular Bone Mineral Density in the Lumbar Spine Is Associated With Prevalent Vertebral Fracture. J Bone Miner Res. 2020 04; 35(4):641-648.View Related Profiles.

Guermazi, Ali
Morgan, Elise
Demissie, Serkalem

PMID: 31886907; PMCID: PMC7145746; DOI: 10.1002/jbmr.3946;

Spartano NL, Demissie S, Himali JJ, Dukes KA, Murabito JM, Vasan RS, Beiser AS, Seshadri S. Accelerometer-determined physical activity and cognitive function in middle-aged and older adults from two generations of the Framingham Heart Study. Alzheimers Dement (N Y). 2019; 5:618-626.View Related Profiles.

Beiser, Alexa
Himali, Jayandra
Murabito, Joanne
Dukes, Kimberly Ann
Spartano, Nicole
Demissie, Serkalem
Seshadri, Sudha

PMID: 31660424; PMCID: PMC6807299; DOI: 10.1016/j.trci.2019.08.007;

Georgakis MK, Malik R, Björkbacka H, Pana TA, Demissie S, Ayers C, Elhadad MA, Fornage M, Beiser AS, Benjamin EJ, Boekholdt SM, Engström G, Herder C, Hoogeveen RC, Koenig W, Melander O, Orho-Melander M, Schiopu A, Söderholm M, Wareham N, Ballantyne CM, Peters A, Seshadri S, Myint PK, Nilsson J, de Lemos JA, Dichgans M. Circulating Monocyte Chemoattractant Protein-1 and Risk of Stroke: Meta-Analysis of Population-Based Studies Involving 17?180 Individuals. Circ Res. 2019 09 27; 125(8):773-782.View Related Profiles.

Beiser, Alexa
Benjamin, Emelia
Demissie, Serkalem
Seshadri, Sudha

PMID: 31476962; PMCID: PMC6763364; DOI: 10.1161/CIRCRESAHA.119.315380;

Hsu YH, Estrada K, Evangelou E, Ackert-Bicknell C, Akesson K, Beck T, Brown SJ, Capellini T, Carbone L, Cauley J, Cheung CL, Cummings SR, Czerwinski S, Demissie S, Econs M, Evans D, Farber C, Gautvik K, Harris T, Kammerer C, Kemp J, Koller DL, Kung A, Lawlor D, Lee M, Lorentzon M, McGuigan F, Medina-Gomez C, Mitchell B, Newman A, Nielson C, Ohlsson C, Peacock M, Reppe S, Richards JB, Robbins J, Sigurdsson G, Spector TD, Stefansson K, Streeten E, Styrkarsdottir U, Tobias J, Trajanoska K, Uitterlinden A, Vandenput L, Wilson SG, Yerges-Armstrong L, Young M, Zillikens MC, Rivadeneira F, Kiel DP, Karasik D. Meta-Analysis of Genomewide Association Studies Reveals Genetic Variants for Hip Bone Geometry. J Bone Miner Res. 2019 07; 34(7):1284-1296. PMID: 30888730; PMCID: PMC6650334; DOI: 10.1002/jbmr.3698;

Lu D, Tripodis Y, Gerstenfeld LC, Demissie S. Clustering of temporal gene expression data with mixtures of mixed effects models with a penalized likelihood. Bioinformatics. 2019 03 01; 35(5):778-786.View Related Profiles.

Gerstenfeld, Louis
Demissie, Serkalem
Tripodis, Yorghos

PMID: 30101356; PMCID: PMC6394398; DOI: 10.1093/bioinformatics/bty696;

Karasik D, Zillikens MC, Hsu YH, Aghdassi A, Akesson K, Amin N, Barroso I, Bennett DA, Bertram L, Bochud M, Borecki IB, Broer L, Buchman AS, Byberg L, Campbell H, Campos-Obando N, Cauley JA, Cawthon PM, Chambers JC, Chen Z, Cho NH, Choi HJ, Chou WC, Cummings SR, de Groot LCPGM, De Jager PL, Demuth I, Diatchenko L, Econs MJ, Eiriksdottir G, Enneman AW, Eriksson J, Eriksson JG, Estrada K, Evans DS, Feitosa MF, Fu M, Gieger C, Grallert H, Gudnason V, Lenore LJ, Hayward C, Hofman A, Homuth G, Huffman KM, Husted LB, Illig T, Ingelsson E, Ittermann T, Jansson JO, Johnson T, Biffar R, Jordan JM, Jula A, Karlsson M, Khaw KT, Kilpeläinen TO, Klopp N, Kloth JSL, Koller DL, Kooner JS, Kraus WE, Kritchevsky S, Kutalik Z, Kuulasmaa T, Kuusisto J, Laakso M, Lahti J, Lang T, Langdahl BL, Lerch MM, Lewis JR, Lill C, Lind L, Lindgren C, Liu Y, Livshits G, Ljunggren Ö, Loos RJF, Lorentzon M, Luan J, Luben RN, Malkin I, McGuigan FE, Medina-Gomez C, Meitinger T, Melhus H, Mellström D, Michaëlsson K, Mitchell BD, Morris AP, Mosekilde L, Nethander M, Newman AB, O'Connell JR, Oostra BA, Orwoll ES, Palotie A, Peacock M, Perola M, Peters A, Prince RL, Psaty BM, Räikkönen K, Ralston SH, Ripatti S, Rivadeneira F, Robbins JA, Rotter JI, Rudan I, Salomaa V, Satterfield S, Schipf S, Shin CS, Smith AV, Smith SB, Soranzo N, Spector TD, Stancáková A, Stefansson K, Steinhagen-Thiessen E, Stolk L, Streeten EA, Styrkarsdottir U, Swart KMA, Thompson P, Thomson CA, Thorleifsson G, Thorsteinsdottir U, Tikkanen E, Tranah GJ, Uitterlinden AG, van Duijn CM, van Schoor NM, Vandenput L, Vollenweider P, Völzke H, Wactawski-Wende J, Walker M, J Wareham N, Waterworth D, Weedon MN, Wichmann HE, Widen E, Williams FMK, Wilson JF, Wright NC, Yerges-Armstrong LM, Yu L, Zhang W, Zhao JH, Zhou Y, Nielson CM, Harris TB, Demissie S, Kiel DP, Ohlsson C. Disentangling the genetics of lean mass. Am J Clin Nutr. 2019 02 01; 109(2):276-287. PMID: 30721968; PMCID: PMC6500901; DOI: 10.1093/ajcn/nqy272;

Samelson EJ, Broe KE, Xu H, Yang L, Boyd S, Biver E, Szulc P, Adachi J, Amin S, Atkinson E, Berger C, Burt L, Chapurlat R, Chevalley T, Ferrari S, Goltzman D, Hanley DA, Hannan MT, Khosla S, Liu CT, Lorentzon M, Mellstrom D, Merle B, Nethander M, Rizzoli R, Sornay-Rendu E, Van Rietbergen B, Sundh D, Wong AKO, Ohlsson C, Demissie S, Kiel DP, Bouxsein ML. Cortical and trabecular bone microarchitecture as an independent predictor of incident fracture risk in older women and men in the Bone Microarchitecture International Consortium (BoMIC): a prospective study. Lancet Diabetes Endocrinol. 2019 01; 7(1):34-43.View Related Profiles.

Liu, Ching-Ti
Demissie, Serkalem

PMID: 30503163; PMCID: PMC6354581; DOI: 10.1016/S2213-8587(18)30308-5;

Kaiser J, Allaire B, Fein PM, Lu D, Jarraya M, Guermazi A, Demissie S, Samelson EJ, Bouxsein ML, Morgan EF. Correspondence between bone mineral density and intervertebral disc degeneration across age and sex. Arch Osteoporos. 2018 11 12; 13(1):123.View Related Profiles.

Guermazi, Ali
Morgan, Elise
Demissie, Serkalem

PMID: 30421154; PMCID: PMC6291246; DOI: 10.1007/s11657-018-0538-1;

Allaire BT, Lu D, Johannesdottir F, Kopperdahl D, Keaveny TM, Jarraya M, Guermazi A, Bredella MA, Samelson EJ, Kiel DP, Anderson DE, Demissie S, Bouxsein ML. Prediction of incident vertebral fracture using CT-based finite element analysis. Osteoporos Int. 2019 Feb; 30(2):323-331.View Related Profiles.

Guermazi, Ali
Demissie, Serkalem

PMID: 30306225; PMCID: PMC6450770; DOI: 10.1007/s00198-018-4716-1;

Noguchi T, Hussein AI, Horowitz N, Carroll D, Gower AC, Demissie S, Gerstenfeld LC. Hypophosphatemia Regulates Molecular Mechanisms of Circadian Rhythm. Sci Rep. 2018 09 13; 8(1):13756.View Related Profiles.

Gower, Adam
Hussein, Amira
Gerstenfeld, Louis
Demissie, Serkalem

PMID: 30213970; PMCID: PMC6137060; DOI: 10.1038/s41598-018-31830-7;

Rozental TD, Walley KC, Demissie S, Caksa S, Martinez-Betancourt A, Parker AM, Tsai JN, Yu EW, Bouxsein ML. Bone Material Strength Index as Measured by Impact Microindentation in Postmenopausal Women With Distal Radius and Hip Fractures. J Bone Miner Res. 2018 04; 33(4):621-626. PMID: 29115684

Zillikens MC, Demissie S, Hsu YH, Yerges-Armstrong LM, Chou WC, Stolk L, Livshits G, Broer L, Johnson T, Koller DL, Kutalik Z, Luan J, Malkin I, Ried JS, Smith AV, Thorleifsson G, Vandenput L, Hua Zhao J, Zhang W, Aghdassi A, Åkesson K, Amin N, Baier LJ, Barroso I, Bennett DA, Bertram L, Biffar R, Bochud M, Boehnke M, Borecki IB, Buchman AS, Byberg L, Campbell H, Campos Obanda N, Cauley JA, Cawthon PM, Cederberg H, Chen Z, Cho NH, Jin Choi H, Claussnitzer M, Collins F, Cummings SR, De Jager PL, Demuth I, Dhonukshe-Rutten RAM, Diatchenko L, Eiriksdottir G, Enneman AW, Erdos M, Eriksson JG, Eriksson J, Estrada K, Evans DS, Feitosa MF, Fu M, Garcia M, Gieger C, Girke T, Glazer NL, Grallert H, Grewal J, Han BG, Hanson RL, Hayward C, Hofman A, Hoffman EP, Homuth G, Hsueh WC, Hubal MJ, Hubbard A, Huffman KM, Husted LB, Illig T, Ingelsson E, Ittermann T, Jansson JO, Jordan JM, Jula A, Karlsson M, Khaw KT, Kilpeläinen TO, Klopp N, Kloth JSL, Koistinen HA, Kraus WE, Kritchevsky S, Kuulasmaa T, Kuusisto J, Laakso M, Lahti J, Lang T, Langdahl BL, Launer LJ, Lee JY, Lerch MM, Lewis JR, Lind L, Lindgren C, Liu Y, Liu T, Liu Y, Ljunggren Ö, Lorentzon M, Luben RN, Maixner W, McGuigan FE, Medina-Gomez C, Meitinger T, Melhus H, Mellström D, Melov S, Michaëlsson K, Mitchell BD, Morris AP, Mosekilde L, Newman A, Nielson CM, O'Connell JR, Oostra BA, Orwoll ES, Palotie A, Parker SCJ, Peacock M, Perola M, Peters A, Polasek O, Prince RL, Räikkönen K, Ralston SH, Ripatti S, Robbins JA, Rotter JI, Rudan I, Salomaa V, Satterfield S, Schadt EE, Schipf S, Scott L, Sehmi J, Shen J, Soo Shin C, Sigurdsson G, Smith S, Soranzo N, Stancáková A, Steinhagen-Thiessen E, Streeten EA, Styrkarsdottir U, Swart KMA, Tan ST, Tarnopolsky MA, Thompson P, Thomson CA, Thorsteinsdottir U, Tikkanen E, Tranah GJ, Tuomilehto J, van Schoor NM, Verma A, Vollenweider P, Völzke H, Wactawski-Wende J, Walker M, Weedon MN, Welch R, Wichmann HE, Widen E, Williams FMK, Wilson JF, Wright NC, Xie W, Yu L, Zhou Y, Chambers JC, Döring A, van Duijn CM, Econs MJ, Gudnason V, Kooner JS, Psaty BM, Spector TD, Stefansson K, Rivadeneira F, Uitterlinden AG, Wareham NJ, Ossowski V, Waterworth D, Loos RJF, Karasik D, Harris TB, Ohlsson C, Kiel DP. Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass. Nat Commun. 2017 11 07; 8(1):1414. PMID: 29116125; PMCID: PMC5676783; DOI: 10.1038/s41467-017-01008-2;

Samelson EJ, Demissie S, Cupples LA, Zhang X, Xu H, Liu CT, Boyd SK, McLean RR, Broe KE, Kiel DP, Bouxsein ML. Diabetes and Deficits in Cortical Bone Density, Microarchitecture, and Bone Size: Framingham HR-pQCT Study. J Bone Miner Res. 2018 01; 33(1):54-62.View Related Profiles.

Liu, Ching-Ti
Cupples, L
Demissie, Serkalem

PMID: 28929525; PMCID: PMC5771832; DOI: 10.1002/jbmr.3240;

Medina-Gomez C, Kemp JP, Dimou NL, Kreiner E, Chesi A, Zemel BS, Bønnelykke K, Boer CG, Ahluwalia TS, Bisgaard H, Evangelou E, Heppe DHM, Bonewald LF, Gorski JP, Ghanbari M, Demissie S, Duque G, Maurano MT, Kiel DP, Hsu YH, C J van der Eerden B, Ackert-Bicknell C, Reppe S, Gautvik KM, Raastad T, Karasik D, van de Peppel J, Jaddoe VWV, Uitterlinden AG, Tobias JH, Grant SFA, Bagos PG, Evans DM, Rivadeneira F. Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locus. Nat Commun. 2017 07 25; 8(1):121. PMID: 28743860; PMCID: PMC5527106; DOI: 10.1038/s41467-017-00108-3;

Zillikens MC, Demissie S, Hsu YH, Yerges-Armstrong LM, Chou WC, Stolk L, Livshits G, Broer L, Johnson T, Koller DL, Kutalik Z, Luan J, Malkin I, Ried JS, Smith AV, Thorleifsson G, Vandenput L, Hua Zhao J, Zhang W, Aghdassi A, Åkesson K, Amin N, Baier LJ, Barroso I, Bennett DA, Bertram L, Biffar R, Bochud M, Boehnke M, Borecki IB, Buchman AS, Byberg L, Campbell H, Campos Obanda N, Cauley JA, Cawthon PM, Cederberg H, Chen Z, Cho NH, Jin Choi H, Claussnitzer M, Collins F, Cummings SR, De Jager PL, Demuth I, Dhonukshe-Rutten RAM, Diatchenko L, Eiriksdottir G, Enneman AW, Erdos M, Eriksson JG, Eriksson J, Estrada K, Evans DS, Feitosa MF, Fu M, Garcia M, Gieger C, Girke T, Glazer NL, Grallert H, Grewal J, Han BG, Hanson RL, Hayward C, Hofman A, Hoffman EP, Homuth G, Hsueh WC, Hubal MJ, Hubbard A, Huffman KM, Husted LB, Illig T, Ingelsson E, Ittermann T, Jansson JO, Jordan JM, Jula A, Karlsson M, Khaw KT, Kilpeläinen TO, Klopp N, Kloth JSL, Koistinen HA, Kraus WE, Kritchevsky S, Kuulasmaa T, Kuusisto J, Laakso M, Lahti J, Lang T, Langdahl BL, Launer LJ, Lee JY, Lerch MM, Lewis JR, Lind L, Lindgren C, Liu Y, Liu T, Liu Y, Ljunggren Ö, Lorentzon M, Luben RN, Maixner W, McGuigan FE, Medina-Gomez C, Meitinger T, Melhus H, Mellström D, Melov S, Michaëlsson K, Mitchell BD, Morris AP, Mosekilde L, Newman A, Nielson CM, O'Connell JR, Oostra BA, Orwoll ES, Palotie A, Parker SCJ, Peacock M, Perola M, Peters A, Polasek O, Prince RL, Räikkönen K, Ralston SH, Ripatti S, Robbins JA, Rotter JI, Rudan I, Salomaa V, Satterfield S, Schadt EE, Schipf S, Scott L, Sehmi J, Shen J, Soo Shin C, Sigurdsson G, Smith S, Soranzo N, Stancáková A, Steinhagen-Thiessen E, Streeten EA, Styrkarsdottir U, Swart KMA, Tan ST, Tarnopolsky MA, Thompson P, Thomson CA, Thorsteinsdottir U, Tikkanen E, Tranah GJ, Tuomilehto J, van Schoor NM, Verma A, Vollenweider P, Völzke H, Wactawski-Wende J, Walker M, Weedon MN, Welch R, Wichmann HE, Widen E, Williams FMK, Wilson JF, Wright NC, Xie W, Yu L, Zhou Y, Chambers JC, Döring A, van Duijn CM, Econs MJ, Gudnason V, Kooner JS, Psaty BM, Spector TD, Stefansson K, Rivadeneira F, Uitterlinden AG, Wareham NJ, Ossowski V, Waterworth D, Loos RJF, Karasik D, Harris TB, Ohlsson C, Kiel DP. Large meta-analysis of genome-wide association studies identifies five loci for lean body mass. Nat Commun. 2017 07 19; 8(1):80. PMID: 28724990; PMCID: PMC5517526; DOI: 10.1038/s41467-017-00031-7;

Karasik D, Demissie S, Lu D, Broe KE, Boyd SK, Liu CT, Hsu YH, Bouxsein ML, Kiel DP. Bone Strength Estimated by Micro-Finite Element Analysis (µFEA) Is Heritable and Shares Genetic Predisposition With Areal BMD: The Framingham Study. J Bone Miner Res. 2017 Nov; 32(11):2151-2156.View Related Profiles.

Liu, Ching-Ti
Demissie, Serkalem

PMID: 28722129; PMCID: PMC5685872; DOI: 10.1002/jbmr.3200;

Hedman ÅK, Mendelson MM, Marioni RE, Gustafsson S, Joehanes R, Irvin MR, Zhi D, Sandling JK, Yao C, Liu C, Liang L, Huan T, McRae AF, Demissie S, Shah S, Starr JM, Cupples LA, Deloukas P, Spector TD, Sundström J, Krauss RM, Arnett DK, Deary IJ, Lind L, Levy D, Ingelsson E. Epigenetic Patterns in Blood Associated With Lipid Traits Predict Incident Coronary Heart Disease Events and Are Enriched for Results From Genome-Wide Association Studies. Circ Cardiovasc Genet. 2017 Jan; 10(1).View Related Profiles.

Liu, Chunyu
Cupples, L
Demissie, Serkalem

PMID: 28213390; PMCID: PMC5331877; DOI: 10.1161/CIRCGENETICS.116.001487;

Hsu YH, Li G, Liu CT, Brody JA, Karasik D, Chou WC, Demissie S, Nandakumar K, Zhou Y, Cheng CH, Gill R, Gibbs RA, Muzny D, Santibanez J, Estrada K, Rivadeneira F, Harris T, Gudnason V, Uitterlinden A, Psaty BM, Robbins JA, Adrienne Cupples L, Kiel DP. Targeted sequencing of genome wide significant loci associated with bone mineral density (BMD) reveals significant novel and rare variants: the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) targeted sequencing study. Hum Mol Genet. 2016 Dec 01; 25(23):5234-5243.View Related Profiles.

Liu, Ching-Ti
Demissie, Serkalem

PMID: 27616567; PMCID: PMC5837042; DOI: 10.1093/hmg/ddw289;

Karasik D, Demissie S, Zhou Y, Lu D, Broe KE, Bouxsein ML, Cupples LA, Kiel DP. Heritability and Genetic Correlations for Bone Microarchitecture: The Framingham Study Families. J Bone Miner Res. 2017 Jan; 32(1):106-114.View Related Profiles.

Year	Publications
1999	3
2000	2
2001	8
2002	6
2003	9
2004	5
2005	10
2006	5
2007	9
2008	8
2009	10
2010	14
2011	10
2012	8
2013	2
2014	2
2015	2
2016	6
2017	7
2018	4
2019	5
2020	3
2021	2
2022	7
2023	6
2024	2
2025	5