Robert A. Stern, PhD
Professor
Boston University School of Medicine
Dept of Neurology

PhD, University of Rhode Island
MA, University of Rhode Island




I am Co-Founder and Director of Clinical Research for the Boston University (BU) Chronic Traumatic Encephalopathy (CTE) Center. A major focus of my current research is on the long-term consequences of repetitive head impacts, including the neuropathological, risk factors (e.g., genetic and head impact exposure), neuroimaging, biomarker development, and clinical diagnosis and descriptions of the neurodegenerative disease, CTE. I am currently lead PI of an NINDS-funded, 7-year, multicenter project examining these issues. From 2010-2019, I was the Clinical Core Director of the NIA-funded BU Alzheimer’s Disease Center (BU ADC); I remain a Senior Investigator for the BU ADC. In these roles, I have been honored to oversee a multidisciplinary group of talented scientists and clinicians and direct the center’s longitudinal research registry, as well as several NIH- and industry-funded diagnostic, prevention, and treatment trials. Other areas of my research program include the diagnosis, risk factors, and treatment of cognitive decline and neuropsychiatric dysfunction in aging. I have also published extensively on the psychometric properties of many widely used tests in neuropsychology, as well as the use of various instruments and biomarkers in the differential diagnosis of Alzheimer’s disease (AD) and AD Related Dementias (ADRD). In addition, I have developed several commonly used tests and instruments, including the Neuropsychological Assessment Battery (NAB). I have had leadership positions in several training programs, have mentored over 40 trainees, and play a key role in the professional development of junior faculty in the BU School of Medicine (BUSM).

Professor
Boston University School of Medicine
Anatomy & Neurobiology


Professor
Boston University School of Medicine
Neurosurgery


Graduate Faculty (Primary Mentor of Grad Students)
Boston University School of Medicine, Graduate Medical Sciences


Director of Clinical Research
Boston University School of Medicine
Chronic Traumatic Encephalopathy Center




Risk for Later-Life Cognitive Impairment, Neurobehavioral Dysregulation, and Dementia in Former Soccer and American Football Players: The Head Impact and Trauma Surveillance Study (HITSS)
02/01/2021 - 01/31/2026 (PI)
NIH/National Institute of Neurological Disorders & Stroke
5R01NS119651-02

Protocol #CNP520A2202J, A randomized, double-blind, placebo-controlled, parallel group study to evaluate the efficacy and safety of CNP520 in participants at risk for the onset of clinical symptoms of
05/01/2018 - 04/30/2025 (PI)
Novartis Pharmaceuticals Corporation


Protocol #API015A2201J, A randomized, double-blind, placebo-controlled, two cohort parallel group study to evaluate the efficacy of CAD106 and CNP520 in participants at risk for the onset of clinical
02/01/2018 - 08/31/2024 (PI)
Novartis Pharmaceuticals Corporation


The A45 Study: Combination anti-amyloid therapy for preclinical Alzheimer's disease
09/30/2019 - 05/31/2024 (PI of Sub-Project / SP)
University of Southern California NIH NIA
5R01AG061848-02

Metformin in Alzheimer's dementia Prevention (MAP)
05/01/2021 - 04/30/2024 (Subcontract PI)
Trustees Of Columbia University In The City Of New York NIH NIA
5R01AG062624-03

Metformin in Alzheimers dementia Prevention (MAP)
08/15/2019 - 04/30/2024 (Subcontract PI)
Trustees Of Columbia University In The City Of New York NIH NIA
5R01AG062624-03

A placebo-controlled, double-blind, parallel-group, bayesian adaptive randomization design and dose regimen-finding study to evaluate the safety tolerability and efficacy of BAN2401 in subjects with
02/01/2013 - 09/28/2023 (PI)
Eisai, Inc


The A3 Study: Ante-Amyloid prevention of Alzheimer's disease
06/01/2019 - 04/30/2023 (PI of Sub-Project / SP)
University of Southern California NIH NIA
1R01AG061848-01

Protocol number BAN2401-G000-303: AHEAD 3-45 Study: A Placebo-Controlled, Double-Blind, Parallel-Treatment Arm, 216 Week Study to Evaluate Efficacy and Safety of Treatment With BAN2401 in Subject
01/01/2020 - 12/31/2022 (PI of Sub-Project / SP)
University of Southern California Eisai, Inc


Anti-Amyloid Treatment in Asymptomatic Alzheimer's Disease (A4 Study)
12/11/2015 - 12/31/2022 (Subcontract PI)
University of Southern California Eli Lilly and Co


Showing 10 of 53 results. Show All Results


Title


Yr Title Project-Sub Proj Pubs
2022 Risk for Later-Life Cognitive Impairment, Neurobehavioral Dysregulation, and Dementia in Former Soccer and American Football Players: The Head Impact and Trauma Surveillance Study (HITSS) 5R01NS119651-02
2022 Chronic Traumatic Encephalopathy: Detection, Diagnosis, Course, and Risk Factors 5U01NS093334-07
2021 Risk for Later-Life Cognitive Impairment, Neurobehavioral Dysregulation, and Dementia in Former Soccer and American Football Players: The Head Impact and Trauma Surveillance Study (HITSS) 1R01NS119651-01
2021 Chronic Traumatic Encephalopathy: Detection, Diagnosis, Course, and Risk Factors 5U01NS093334-06 24
2020 Chronic Traumatic Encephalopathy: Detection, Diagnosis, Course, and Risk Factors 5U01NS093334-05 24
2019 Chronic Traumatic Encephalopathy: Detection, Diagnosis, Course, and Risk Factors 3U01NS093334-04S1 24
2019 Chronic Traumatic Encephalopathy: Detection, Diagnosis, Course, and Risk Factors 5U01NS093334-04 24
2018 Chronic Traumatic Encephalopathy: Detection, Diagnosis, Course, and Risk Factors 5U01NS093334-03 24
2018 Core B: Clinical Core 5P30AG013846-22-6895 874
2017 Chronic Traumatic Encephalopathy: Detection, Diagnosis, Course, and Risk Factors 5U01NS093334-02 24
Showing 10 of 31 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Atherton K, Han X, Chung J, Cherry JD, Baucom Z, Saltiel N, Nair E, Abdolmohammadi B, Uretsky M, Khan MM, Shea C, Durape S, Martin BM, Palmisano JN, Farrell K, Nowinski CJ, Alvarez VE, Dwyer B, Daneshvar DH, Katz DI, Goldstein LE, Cantu RC, Kowall NW, Alosco ML, Huber BR, Tripodis Y, Crary JF, Farrer L, Stern RA, Stein TD, McKee AC, Mez J. Association of APOE Genotypes and Chronic Traumatic Encephalopathy. JAMA Neurol. 2022 Aug 01; 79(8):787-796.View Related Profiles. PMID: 35759276; PMCID: PMC9237800; DOI: 10.1001/jamaneurol.2022.1634;
     
  2. Morrison MS, Aparicio HJ, Blennow K, Zetterberg H, Ashton NJ, Karikari TK, Tripodis Y, Martin B, Palmisano JN, Sugarman MA, Frank B, Steinberg EG, Turk KW, Budson AE, Au R, Goldstein LE, Jun GR, Kowall NW, Killiany R, Qiu WQ, Stern RA, Mez J, McKee AC, Stein TD, Alosco ML. Antemortem plasma phosphorylated tau (181) predicts Alzheimer's disease neuropathology and regional tau at autopsy. Brain. 2022 May 13.View Related Profiles. PMID: 35554506; DOI: 10.1093/brain/awac175;
     
  3. Frank B, Ally M, Tripodis Y, Puzo C, Labriolo C, Hurley L, Martin B, Palmisano J, Chan L, Steinberg E, Turk K, Budson A, O'Connor M, Au R, Qiu WQ, Goldstein L, Kukull W, Kowall N, Killiany R, Stern R, Stein T, McKee A, Mez J, Alosco M. Trajectories of Cognitive Decline in Brain Donors With Autopsy-Confirmed Alzheimer Disease and Cerebrovascular Disease. Neurology. 2022 Jun 14; 98(24):e2454-e2464.View Related Profiles. PMID: 35444054; PMCID: PMC9231841; DOI: 10.1212/WNL.0000000000200304;
     
  4. Phelps A, Alosco ML, Baucom Z, Hartlage K, Palmisano JN, Weuve J, Mez J, Tripodis Y, Stern RA. Association of Playing College American Football With Long-term Health Outcomes and Mortality. JAMA Netw Open. 2022 Apr 01; 5(4):e228775.View Related Profiles. PMID: 35442450; PMCID: PMC9021915; DOI: 10.1001/jamanetworkopen.2022.8775;
     
  5. Turk KW, Geada A, Alvarez VE, Xia W, Cherry JD, Nicks R, Meng G, Daley S, Tripodis Y, Huber BR, Budson AE, Dwyer B, Kowall NW, Cantu RC, Goldstein LE, Katz DI, Stern RA, Alosco ML, Mez J, McKee AC, Stein TD. A comparison between tau and amyloid-ß cerebrospinal fluid biomarkers in chronic traumatic encephalopathy and Alzheimer disease. Alzheimers Res Ther. 2022 02 09; 14(1):28.View Related Profiles. PMID: 35139894; PMCID: PMC8830027; DOI: 10.1186/s13195-022-00976-y;
     
  6. Foley ÉM, Tripodis Y, Yhang E, Koerte IK, Martin BM, Palmisano J, Makris N, Schultz V, Lepage C, Muehlmann M, Wróbel PP, Guenette JP, Cantu RC, Lin AP, Coleman M, Mez J, Bouix S, Shenton ME, Stern RA, Alosco ML. Quantifying and Examining Reserve in Symptomatic Former National Football League Players. J Alzheimers Dis. 2022; 85(2):675-689.View Related Profiles. PMID: 34864657; PMCID: PMC8926024; DOI: 10.3233/JAD-210379;
     
  7. Alosco ML, Mian AZ, Buch K, Farris CW, Uretsky M, Tripodis Y, Baucom Z, Martin B, Palmisano J, Puzo C, Ang TFA, Joshi P, Goldstein LE, Au R, Katz DI, Dwyer B, Daneshvar DH, Nowinski C, Cantu RC, Kowall NW, Huber BR, Alvarez VE, Stern RA, Stein TD, Killiany RJ, McKee AC, Mez J. Structural MRI profiles and tau correlates of atrophy in autopsy-confirmed CTE. Alzheimers Res Ther. 2021 12 07; 13(1):193.View Related Profiles. PMID: 34876229; PMCID: PMC8653514; DOI: 10.1186/s13195-021-00928-y;
     
  8. Frank B, Ally M, Brekke B, Zetterberg H, Blennow K, Sugarman MA, Ashton NJ, Karikari TK, Tripodis Y, Martin B, Palmisano JN, Steinberg EG, Simkina I, Turk KW, Budson AE, O'Connor MK, Au R, Goldstein LE, Jun GR, Kowall NW, Stein TD, McKee AC, Killiany R, Qiu WQ, Stern RA, Mez J, Alosco ML. Plasma p-tau181 shows stronger network association to Alzheimer's disease dementia than neurofilament light and total tau. Alzheimers Dement. 2022 Aug; 18(8):1523-1536.View Related Profiles. PMID: 34854549; PMCID: PMC9160800; DOI: 10.1002/alz.12508;
     
  9. Daneshvar DH, Mez J, Alosco ML, Baucom ZH, Mahar I, Baugh CM, Valle JP, Weuve J, Paganoni S, Cantu RC, Zafonte RD, Stern RA, Stein TD, Tripodis Y, Nowinski CJ, McKee AC. Incidence of and Mortality From Amyotrophic Lateral Sclerosis in National Football League Athletes. JAMA Netw Open. 2021 12 01; 4(12):e2138801.View Related Profiles. PMID: 34910152; PMCID: PMC8674746; DOI: 10.1001/jamanetworkopen.2021.38801;
     
  10. Uretsky M, Bouix S, Killiany RJ, Tripodis Y, Martin B, Palmisano J, Mian AZ, Buch K, Farris C, Daneshvar DH, Dwyer B, Goldstein L, Katz D, Nowinski C, Cantu R, Kowall N, Huber BR, Stern RA, Alvarez VE, Stein TD, McKee A, Mez J, Alosco ML. Association Between Antemortem FLAIR White Matter Hyperintensities and Neuropathology in Brain Donors Exposed to Repetitive Head Impacts. Neurology. 2022 01 04; 98(1):e27-e39.View Related Profiles. PMID: 34819338; PMCID: PMC8726571; DOI: 10.1212/WNL.0000000000013012;
     
Showing 10 of 221 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 221 publications over 36 distinct years, with a maximum of 21 publications in 2018

YearPublications
19861
19871
19891
19901
19914
19926
19936
19943
19955
19966
19974
19981
19993
20005
20011
20022
20036
20042
20051
20062
20074
20085
20094
20105
20117
201210
20136
201412
201514
201614
201712
201821
201916
202013
202111
20226


Recent (within 3 months)

Bruce Murray spent years heading the ball. He worries it took a toll.

The Washington Post 7/5/2022

Older

What is CTE and How Often Are Soccer Players Diagnosed With It?

NBC 10 Boston 6/30/2022

Evidence of CTE Rare in Military Personnel

MedPage Today 6/8/2022

Long-Term Health Outcomes Associated with College Football

Medical Research 4/23/2022

Former College Football Players Suffer More Brain Disorders as They Age

HealthDay 4/21/2022

Cognitive impairment, headaches, CVD more common in former college football players

Healio 4/21/2022

Study links college football with cognitive impairment, other health issues

United Press International 4/20/2022

College football players more likely to have brain disorders, Boston University CTE study finds

WCVB 5 4/20/2022

College football players more likely to have brain disorders: Boston University CTE study

Boston Herald 4/20/2022

‘So many important questions to answer’: BU research indicates college football players more likely to develop brain disorders

WHDH 4/20/2022

Study to examine the risks for brain disorders from repetitive head impacts in contact sports

News Medical 3/8/2022

Boston University brain health researchers recruiting people who played soccer or tackle football

Boston Herald 3/8/2022

BU, UCSF recruiting thousands for new study of head injury in sports

WCVB 3/7/2022

Everyday people fear they have CTE. A dubious market has sprung up to treat them

NPR 12/23/2021

Non-pro athletes may also be at increased risk for CTE, neuroscientist says

NPR 12/19/2021

New NINDS Consensus Criteria for Traumatic Encephalopathy Syndrome Not Yet Ready for the Clinic Just Yet, but Useful for Research

NeurologyToday 4/15/2021

Olympic Bobsledder Who Killed Himself Likely Had C.T.E.

New York Times 4/8/2021

We’re one step closer to diagnosing CTE in living patients

Advisory Board 3/29/2021

The future of CTE and football

Axios 3/23/2021

Criteria Proposed to Diagnose Clinical Syndrome Tied to CTE

Medpage Today 3/15/2021

Doctors provide consensus symptoms of CTE among living, a major step for researchers

The Washington Post 3/15/2021

Abby Wambach and Brandi Chastain Hope Their Deaths Ultimately Make Soccer Safer

Sportscasting 3/12/2021

Black Former NFL Players Say Racial Bias Skews Concussion Payouts

The New York Times 8/25/2020

Sledding athletes are taking their lives

The New York Times 7/26/2020

Repeated Head Impacts Linked To Depression In Later Life

Ministry of Sport 7/21/2020

Repeat Head Impacts May Lead to Depression Later

Futurity 6/30/2020

Sportswomen asked to donate brains for vital dementia research

The Telegraph 11/30/2019

Boxing & MMA: Are They Safe?

MetroWest Daily News 11/17/2019

Older Retired Soccer Players Prone to Neurodegeneration

Alzforum 11/8/2019

Pro Soccer Players at High Risk for Death From Alzheimer's, ALS, Parkinson’s

Medscape 11/5/2019

Teen Girls Suffer As Many Concussions Playing SOCCER As Boys Do Playing Football

The Daily Mail 11/3/2019

Does heading soccer balls hurt women’s brains? U.S. soccer stars take part in new study

NBC News 10/25/2019

Does Heading Soccer Balls Hurt Women's Brains? U.S. Soccer Stars Take Part in New Study

Today Show 10/25/2019

Should Massachusetts Ban Youth Tackle Football?

WGBH’s Greater Boston 10/24/2019

Battle over banning youth tackle football in Massachusetts

Boston Herald 10/22/2019

Mass. Lawmakers Debate Future of Youth Football Amid Concussion Concerns

NBC Boston 10/22/2019

Pro soccer players more likely to die from dementia, study finds

NBC News 10/22/2019

Study Finds Soccer Players at Higher Risk for Dementia, But Leaves Larger Question of Why

Yahoo Sports 10/21/2019

Study Raises Fresh Dementia Concerns From Playing Pro Soccer

AP 10/21/2019

Dementia Deaths High in Former Pro Soccer Players

MedPageToday 10/21/2019

Study Shows More Thinking Problems in Former Pro Soccer Players

Reuters 10/21/2019

Why Women’s Soccer Players are Worried About Their Brains

Bleacher Report 9/10/2019

Women's Soccer Stars Concerned About Trauma From Repetitive Head Impact

NPR 9/5/2019

The NFL Concussion Settlement Is Pure Evil

Vice 8/26/2019

Women's World Cup Highlights Sex Differences - In Medical Research

Forbes 7/7/2019

How Does CTE Impact Women? Former Soccer Stars Join the First All-Female CTE Study at BU

BU Today 7/3/2019

Former US Women's Soccer Players to Take Part in BU CTE Study

NBC Boston 6/28/2019

Former US Women’s Soccer Stars to take part in Boston University brain study

Boston 25 News 6/28/2019

Akers, Chastain to take part in new CTE study

ESPN 6/28/2019

BU Researchers to Launch a CTE Study of Former Female Soccer Players

Boston Magazine 6/28/2019

New CTE Study for Women's Soccer

CBS Evening News 6/27/2019

BU Launches CTE Study of Former Female Soccer Players

Boston Globe 6/27/2019

Brandi Chastain, Michelle Akers launch landmark CTE study for women's soccer: "We can't ignore this anymore"

CBS This Morning 6/27/2019

Female Soccer Stars Sign On To Landmark CTE Research At Boston University

CBS Boston 6/27/2019

Worried About all the Headers They Took, Former USWNT Stars to Participate in CTE Study

Washington Post 6/27/2019

On the Precipice of Memory Loss: Pursuing Better Diagnostic Tools for Patients with CTE and Other Neurodegenerative Disorders

Genetic Literacy Project 6/13/2019

Tau and Amyloid Deposition in Living Former NFL Players

Neurology Advisor 6/12/2019

Toward Diagnosing CTE in Living People

Science and Technology Research News 5/7/2019

For Patients With Memory Loss, Working Towards Better Diagnosis

Undark 5/6/2019

BU researchers suggest hope for finding CTE clinical diagnosis

Daily Free Press 4/25/2019

CAN BRAIN SCANS SPOT CTE IN THE LIVING?

Futurity 4/16/2019

Brain Scans Show High Tau Levels in Living Former Football Players with Suspected CTE

Neurology Today 4/16/2019

In Football Players With Possible CTE, Tau-PET Reveals Subtle Tau Deposition

ALZFORUM 4/12/2019

PET Scans Reveal Elevated Tau in NFL Players’ Brains

The Scientist 4/12/2019

Researchers A Step Closer To Detecting CTE In Living People

Tech Times 4/11/2019

Finding CTE in Living People? BU Just Got Closer to Doing It

Boston Magazine 4/11/2019

Brain Scans May Reveal Concussion Damage, CTE In Living Athletes

Boston 25 News 4/11/2019

New Hope For Diagnosing CTE In Living Patients

WGBH Radio 4/11/2019

Toward Diagnosing CTE in Living People

BU Today 4/11/2019

Boston University Study Suggests CTE Diagnosis In Living Patients Possible

WCVB ABC 4/11/2019

Doctors May Have Found a Way to Reveal Concussion Damage in Living Football Players

TIME 4/11/2019

CTE in Pro Football Players: Evidence Piles Up

Medpage Today 4/10/2019

Former NFL Players Have Higher Tau Levels Than Non-Athletes

Healio 4/10/2019

NFL Retirees Help Scientists Develop Early Test for Brain Condition CTE

HealthDay News 4/10/2019

Study Suggests Path To Detecting CTE In The Living

ESPN 4/10/2019

A Study Of NFL Players' Brains Might Help Diagnose CTE In The Living

CNN 4/10/2019

Brain Scans On Former NFL Players Detect Abnormal Proteins Found In CTE

NBC News 4/10/2019

CTE Researchers Discover Possible Step Toward Diagnostic Test For Living Patients

Boston.com 4/10/2019

Boston University Study Suggests A Way To Diagnose CTE In Living People

The Boston Globe 4/10/2019

CTE Researchers Discover Possible Step Toward Diagnostic Test For Living Patients

The Washington Post 4/10/2019

Study Raises Hopes Of Someday Using PET Scan To Link Brain Tau To CTE Symptoms

Reuters Health 4/10/2019

Brain Scans May Reveal Concussion Damage In Living Athletes

Associated Press 4/10/2019

Abnormal Levels of a Protein Linked to C.T.E. Found in N.F.L Players’ Brains, Study Shows

The New York Times 4/10/2019

Brain Scans May Reveal Concussion Damage in Living Athletes

NBC 10 Boston 4/10/2019

Kiwanis Help Those In Need

The Eagle-Tribune 1/13/2019

Gary Plummer Gets His Mind Right

Sports Illustrated 9/20/2018

Playing Football Before Age 12 Could Lead to Cognitive and Mood Disorders

PBS 9/19/2017

2019 Boston University School of Medicine: Jack Spivack 2019 Distinguished Neuroscientist Award
2016 University of Alabama: Visiting Professor Lecture
2016 Boston University School of Medicine: Faculty Research Award
2016 Ranked #7 in USA Today’s “Top 100 Important NFL People”
2016 Ranked #57 in Sports Illustrated’s MMQB 100
2014 Mayo Clinic: Visiting Speaker
2008 Alzheimer’s Association MA/NH Chapter: National Research Award
2001 American Neuropsychiatric Association: Fellow
2001 National Academy of Neuropsychology: Fellow
1999 Brown Medicine School: Outstanding Teaching Award in Psychology
1997 Brown University: Master of Arts ad eundem
1997 National Alliance for Research on Schizophrenia & Depression (NARSAD): Independent Investigator Award
1988 Phi Kappa Phi National Honor Society: Inductee
1984 Psi Chi National Honor Society in Psychology: Inductee
1980 Wesleyan University: Heideman Award (for Community Service)
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Alzheimer's Disease
Chronic Traumatic Encephalopathy
Concussion
Dementia
Neuropsychology
Contact for Mentoring:

72 E. Concord St Robinson (B)
Boston MA 02118
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