Ella Zeldich, PhD
Research Assistant Professor
Boston University School of Medicine
Dept of Anatomy & Neurobiology

PhD, Tel Aviv University (TAU)
MS, Tel Aviv University (TAU)

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Ella Zeldich, PhD, is an Instructor of Anatomy & Neurobiology at Boston University School of Medicine. She joined Dr. Carmela Abraham's lab as a postdoctoral associate in 2011. She has been studying the link between Klotho and myelin. One of the laboratory's focuses is the reduction of the accumulation of neurotoxic amyloid beta (Abeta), which is the main component of the amyloid plaques found in the brains of Alzheimer patients. Her research interests are Alzheimer’s disease and aging, neuroprotection, and klotho transcriptional regulation.

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. Chen CD, Rudy MA, Zeldich E, Abraham CR. A method to specifically activate the Klotho promoter by using zinc finger proteins constructed from modular building blocks and from naturally engineered Egr1 transcription factor backbone. FASEB J. 2020 Jun; 34(6):7234-7246.View Related Profiles. PMID: 32347987
     
  2. Chen CD, Li Y, Chen AK, Rudy MA, Nasse JS, Zeldich E, Polanco TJ, Abraham CR. Identification of the cleavage sites leading to the shed forms of human and mouse anti-aging and cognition-enhancing protein Klotho. PLoS One. 2020; 15(1):e0226382.View Related Profiles. PMID: 31929539
     
  3. Zeldich E, Chen CD, Boden E, Howat B, Nasse JS, Zeldich D, Lambert AG, Yuste A, Cherry JD, Mathias RM, Ma Q, Lau NC, McKee AC, Hatzipetros T, Abraham CR. Klotho Is Neuroprotective in the Superoxide Dismutase (SOD1G93A) Mouse Model of ALS. J Mol Neurosci. 2019 Oct; 69(2):264-285.View Related Profiles. PMID: 31250273
     
  4. Chen CD, Zeldich E, Khodr C, Camara K, Tung TY, Lauder EC, Mullen P, Polanco TJ, Liu YY, Zeldich D, Xia W, Van Nostrand WE, Brown LE, Porco JA, Abraham CR. Small Molecule Amyloid-ß Protein Precursor Processing Modulators Lower Amyloid-ß Peptide Levels via cKit Signaling. J Alzheimers Dis. 2019; 67(3):1089-1106.View Related Profiles. PMID: 30776010
     
  5. Ikezu T, Chen C, DeLeo AM, Zeldich E, Fallin MD, Kanaan NM, Lunetta KL, Abraham CR, Logue MW, Farrer LA. Tau Phosphorylation is Impacted by Rare AKAP9 Mutations Associated with Alzheimer Disease in African Americans. J Neuroimmune Pharmacol. 2018 06; 13(2):254-264.View Related Profiles. PMID: 29516269
     
  6. Chen CD, Zeldich E, Li Y, Yuste A, Abraham CR. Activation of the Anti-Aging and Cognition-Enhancing Gene Klotho by CRISPR-dCas9 Transcriptional Effector Complex. J Mol Neurosci. 2018 Feb; 64(2):175-184.View Related Profiles. PMID: 29352444
     
  7. Abraham CR, Mullen PC, Tucker-Zhou T, Chen CD, Zeldich E. Klotho Is a Neuroprotective and Cognition-Enhancing Protein. Vitam Horm. 2016; 101:215-38.View Related Profiles. PMID: 27125744; DOI: 10.1016/bs.vh.2016.02.004;
     
  8. Zeldich E, Chen CD, Avila R, Medicetty S, Abraham CR. The Anti-Aging Protein Klotho Enhances Remyelination Following Cuprizone-Induced Demyelination. J Mol Neurosci. 2015 Oct; 57(2):185-96.View Related Profiles. PMID: 26067431; DOI: 10.1007/s12031-015-0598-2;
     
  9. Chen CD, Tung TY, Liang J, Zeldich E, Tucker Zhou TB, Turk BE, Abraham CR. Identification of cleavage sites leading to the shed form of the anti-aging protein klotho. Biochemistry. 2014 Sep 2; 53(34):5579-87.View Related Profiles. PMID: 25110992; PMCID: PMC4151695; DOI: 10.1021/bi500409n;
     
  10. Jun G, Asai H, Zeldich E, Drapeau E, Chen C, Chung J, Park JH, Kim S, Haroutunian V, Foroud T, Kuwano R, Haines JL, Pericak-Vance MA, Schellenberg GD, Lunetta KL, Kim JW, Buxbaum JD, Mayeux R, Ikezu T, Abraham CR, Farrer LA. PLXNA4 is associated with Alzheimer disease and modulates tau phosphorylation. Ann Neurol. 2014 Sep; 76(3):379-92.View Related Profiles. PMID: 25043464; DOI: 10.1002/ana.24219;
     
Showing 10 of 26 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 26 publications over 14 distinct years, with a maximum of 4 publications in 2014

YearPublications
20021
20043
20051
20072
20081
20092
20123
20131
20144
20151
20161
20182
20192
20202

In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Neurogenesis
IPS Cell
Oligodendrocytes
Organoids
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72 E. Concord St Silvio Conte (K)
Boston MA 02118
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