PhD, University of Pennsylvania

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Yr Title Project-Sub Proj Pubs
2020 Mechanisms by which TLR9-deficiency and FasL Promote Cutaneous Lupus 5R21AI145097-02 1
2020 Mechanisms by which TLR9-deficiency and FasL Promote Cutaneous Lupus 5R21AI145097-02 1
2020 Training in the Molecular Basis of Autoimmunity and Autoinflammation 5T32AI132152-03 2
2020 Regulation of Lupus by Cytosolic DNA Sensors 5R01AI128358-04 4
2019 Mechanisms by which TLR9-deficiency and FasL Promote Cutaneous Lupus 1R21AI145097-01 1
2019 Training in the Molecular Basis of Autoimmunity and Autoinflammation 5T32AI132152-02 2
2019 Innate Immune activation of Cutaneous Lupus 5R21AI136253-02
2019 Regulation of Lupus by Cytosolic DNA Sensors 5R01AI128358-03 4
2019 Distinct Functional Outcomes of BCR/TLR7 and BCR/TLR9 Co-engagement 5R01AR066808-05 17
2018 Training in the Molecular Basis of Autoimmunity and Autoinflammation 1T32AI132152-01A1 2
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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. Giles JR, Neves AT, Marshak-Rothstein A, Shlomchik MJ. Autoreactive helper T cells alleviate the need for intrinsic TLR signaling in autoreactive B cell activation. JCI Insight. 2017 02 23; 2(4):e90870. PMID: 28239656; DOI: 10.1172/jci.insight.90870;
  2. Baum R, Sharma S, Organ JM, Jakobs C, Hornung V, Burr DB, Marshak-Rothstein A, Fitzgerald KA, Gravallese EM. STING Contributes to Abnormal Bone Formation Induced by Deficiency of DNase II in Mice. Arthritis Rheumatol. 2017 Feb; 69(2):460-471. PMID: 27740718; DOI: 10.1002/art.39863;
  3. Krishnan A, Fei F, Jones A, Busto P, Marshak-Rothstein A, Ksander BR, Gregory-Ksander M. Overexpression of Soluble Fas Ligand following Adeno-Associated Virus Gene Therapy Prevents Retinal Ganglion Cell Death in Chronic and Acute Murine Models of Glaucoma. J Immunol. 2016 Dec 15; 197(12):4626-4638. PMID: 27849168
  4. Pawaria S, Sharma S, Baum R, Nündel K, Busto P, Gravallese EM, Fitzgerald KA, Marshak-Rothstein A. Taking the STING out of TLR-driven autoimmune diseases: good, bad, or indifferent? J Leukoc Biol. 2017 Jan; 101(1):121-126. PMID: 27531928; DOI: 10.1189/jlb.3MR0316-115R;
  5. Bossaller L, Christ A, Pelka K, Nündel K, Chiang PI, Pang C, Mishra N, Busto P, Bonegio RG, Schmidt RE, Latz E, Marshak-Rothstein A. TLR9 Deficiency Leads to Accelerated Renal Disease and Myeloid Lineage Abnormalities in Pristane-Induced Murine Lupus. J Immunol. 2016 Aug 15; 197(4):1044-53.View Related Profiles. PMID: 27354219; DOI: 10.4049/jimmunol.1501943;
  6. Baum R, Nündel K, Pawaria S, Sharma S, Busto P, Fitzgerald KA, Gravallese EM, Marshak-Rothstein A. Synergy between Hematopoietic and Radioresistant Stromal Cells Is Required for Autoimmune Manifestations of DNase II-/-IFNaR-/- Mice. J Immunol. 2016 Feb 1; 196(3):1348-54. PMID: 26729810; PMCID: PMC4724517; DOI: 10.4049/jimmunol.1502130;
  7. Moody KL, Uccellini MB, Avalos AM, Marshak-Rothstein A, Viglianti GA. Toll-Like Receptor-Dependent Immune Complex Activation of B Cells and Dendritic Cells. Methods Mol Biol. 2016; 1390:249-72.View Related Profiles. PMID: 26803634; DOI: 10.1007/978-1-4939-3335-8_16;
  8. Marshak-Rothstein A. Autoimmunity--promoting and stabilizing innate immunity 'UNWUCHT'. Immunol Rev. 2016 Jan; 269(1):7-10. PMID: 26683141; DOI: 10.1111/imr.12387;
  9. Matsumoto H, Murakami Y, Kataoka K, Notomi S, Mantopoulos D, Trichonas G, Miller JW, Gregory MS, Ksander BR, Marshak-Rothstein A, Vavvas DG. Membrane-bound and soluble Fas ligands have opposite functions in photoreceptor cell death following separation from the retinal pigment epithelium. Cell Death Dis. 2015; 6:e1986. PMID: 26583327; PMCID: PMC4670938; DOI: 10.1038/cddis.2015.334;
  10. Brodeur TY, Robidoux TE, Weinstein JS, Craft J, Swain SL, Marshak-Rothstein A. IL-21 Promotes Pulmonary Fibrosis through the Induction of Profibrotic CD8+ T Cells. J Immunol. 2015 Dec 1; 195(11):5251-60. PMID: 26519529; PMCID: PMC4655158; DOI: 10.4049/jimmunol.1500777;
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