Bela Suki, PhD
Professor
Boston University College of Engineering
Dept of Biomedical Engineering

PhD, József Attila University



Dr. Béla Suki received his PhD from the University of Szeged (Hungary) in 1987 and currently is a professor of Biomedical Engineering at Boston University. He is an elected Fellow of the American Institute for Medical and Biological Engineering and the Biomedical Engineering Society. He also received a presidential award from the National Institutes of Health. His research interests include respiratory physiology, tissue homeostasis, modeling nonlinear and network phenomena in physiology and biology as well as development of medical devices, one of which has been tested in a clinical trial.

Dr. Suki’s current research involves evaluating the effects of fluctuations in mechanical conditions on cell function, called Fluctuation-Driven Mechanotransduction. Specifically, mechanotransduction in the laboratory is always studied using sinusoidal stretching. However, in the body, cells are never exposed to strictly monotonous mechanical perturbations. Fluctuations appear to influence essential cell functions such as metabolism and protein production. This has practical and clinical implications: during mechanical ventilation, adding variability improves gas exchange, as well as general cell function. His other fields of interest include the effects of mechanical forces on the extracellular matrix in health and disease, such as chronic obstructive pulmonary disease. His current work also includes computational modeling of large biological networks as well as medical device development.


A multi-scale computational model of the extracellular matrix of the lung
06/01/2018 - 05/31/2023 (PI)
NIH/National Heart, Lung, and Blood Institute
5U01HL139466-04

Cellular resolution imaging of drug delivery into tumors in functioning ex vivo lung
01/01/2022 - 12/31/2022 (Multi-PI)
PI: Bela Suki, PhD
Johnson & Johnson Enterprise Innovation, Inc.


Biomechanics-enhanced artificial intelligence in lung cancer detection
06/01/2020 - 12/31/2021 (Multi-PI)
PI: Bela Suki, PhD
Johnson & Johnson Enterprise Innovation, Inc.


A universal mechanobiology tool for drug discovery in lung diseases
09/20/2019 - 06/30/2021 (Subcontract PI)
Mechanobiologix, LLC NIH NHLBI
1R41HL147673-01A1

Billing Agreement for Peijiang Wang
01/01/2018 - 09/02/2018 (Subcontract PI)
Massachusetts Institute of Technology NIH NIGMS
5R01GM049039-22

Monitoring contractile forces during airway constriction
08/01/2016 - 07/31/2018 (Subcontract PI)
Beth Israel Deaconess Medical Center, Inc NIH NHLBI
5R21HL123522-02

Personalized Mechanical Ventilation for the Injured Lung
08/01/2014 - 03/31/2018 (Subcontract PI)
University of Vermont & State Agricultural College NIH NHLBI
5R01HL124052-03

Billing Agreement for Peijiang Wang
08/21/2017 - 12/31/2017 (Subcontract PI)
Massachusetts Institute of Technology Boston Scientific Co


Billing Agreement for Peijiang Wang - Study of Sub-Acute Fracture with FRS
04/14/2017 - 08/31/2017 (PI)
Massachusetts Institute of Technology


Pulmonary arterial endothelial stiffness and shear-stress induced signaling
07/15/2015 - 06/30/2017 (PI)
NIH/National Heart, Lung, and Blood Institute
5R21HL126040-02

Showing 10 of 22 results. Show All Results


Title


Yr Title Project-Sub Proj Pubs
2022 A multi-scale computational model of the extracellular matrix of the lung 5U01HL139466-05
2021 A multi-scale computational model of the extracellular matrix of the lung 5U01HL139466-04 5
2020 A multi-scale computational model of the extracellular matrix of the lung 5U01HL139466-03 5
2019 A universal mechanobiology tool for drug discovery in lung diseases 1R41HL147673-01A1
2019 A multi-scale computational model of the extracellular matrix of the lung 5U01HL139466-02 5
2018 A multi-scale computational model of the extracellular matrix of the lung 1U01HL139466-01 5
2016 Pulmonary arterial endothelial stiffness and shear-stress induced signaling 5R21HL126040-02 9
2015 Pulmonary arterial endothelial stiffness and shear-stress induced signaling 1R21HL126040-01A1 9
2014 Endogenous surfactant therapy for the developing lung 5R01HL111745-03 9
2013 Endogenous surfactant therapy for the developing lung 5R01HL111745-02 9
Showing 10 of 32 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Milkovich N, Gkousioudi A, Seta F, Suki B, Zhang Y. Harmonic Distortion of Blood Pressure Waveform as a Measure of Arterial Stiffness. Front Bioeng Biotechnol. 2022; 10:842754.View Related Profiles. PMID: 35433650; PMCID: PMC9006055; DOI: 10.3389/fbioe.2022.842754;
     
  2. Bartolák-Suki E, Mondoñedo JR, Suki B. Mechano-inflammatory sensitivity of ACE2: Implications for the regional distribution of SARS-CoV-2 injury in the lung. Respir Physiol Neurobiol. 2022 02; 296:103804.View Related Profiles. PMID: 34678474; PMCID: PMC8524802; DOI: 10.1016/j.resp.2021.103804;
     
  3. Jawde SB, Karrobi K, Roblyer D, Vicario F, Herrmann J, Casey D, Lutchen KR, Stamenovic D, Bates JHT, Suki B. Inflation instability in the lung: an analytical model of a thick-walled alveolus with wavy fibres under large deformations. J R Soc Interface. 2021 10; 18(183):20210594.View Related Profiles. PMID: 34637644; PMCID: PMC8510704; DOI: 10.1098/rsif.2021.0594;
     
  4. Zeldich D, Bou Jawde S, Herrmann J, Arnaout L, Griffin M, Grunfeld N, Zhang Y, Krishnan R, Bartolák-Suki E, Suki B. Stabilizing breathing pattern using local mechanical vibrations: comparison of deterministic and stochastic stimulations in rodent models of apnea of prematurity. Biomed Eng Lett. 2021 Nov; 11(4):383-392.View Related Profiles. PMID: 34490067; PMCID: PMC8409477; DOI: 10.1007/s13534-021-00203-x;
     
  5. Casey DT, Bou Jawde S, Herrmann J, Mori V, Mahoney JM, Suki B, Bates JHT. Percolation of collagen stress in a random network model of the alveolar wall. Sci Rep. 2021 08 17; 11(1):16654. PMID: 34404841; PMCID: PMC8371101; DOI: 10.1038/s41598-021-95911-w;
     
  6. Bela Suki. Structure and function of the extracellular matrix: A multiscale quantitative approach. Academic Press. 2021.
  7. Tanabe N, Sato S, Suki B, Hirai T. Fractal Analysis of Lung Structure in Chronic Obstructive Pulmonary Disease. Front Physiol. 2020; 11:603197. PMID: 33408642; PMCID: PMC7779609; DOI: 10.3389/fphys.2020.603197;
     
  8. Mori V, Smith BJ, Suki B, Bates JHT. Modeling Lung Derecruitment in VILI Due to Fluid-Occlusion: The Role of Emergent Behavior. Front Physiol. 2020; 11:542744. PMID: 33192546; PMCID: PMC7662071; DOI: 10.3389/fphys.2020.542744;
     
  9. Suki B, Herrmann J, Bates JHT. An Analytic Model of Tissue Self-Healing and Its Network Implementation: Application to Fibrosis and Aging. Front Physiol. 2020; 11:583024. PMID: 33250776; PMCID: PMC7673435; DOI: 10.3389/fphys.2020.583024;
     
  10. Herrmann J, Mori V, Bates JHT, Suki B. Modeling lung perfusion abnormalities to explain early COVID-19 hypoxemia. Nat Commun. 2020 09 28; 11(1):4883. PMID: 32985528; PMCID: PMC7522238; DOI: 10.1038/s41467-020-18672-6;
     
Showing 10 of 257 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 257 publications over 36 distinct years, with a maximum of 20 publications in 2011

YearPublications
19861
19872
19893
19904
19912
19925
19936
19948
19957
19965
19976
19986
19996
20003
20019
20024
200311
200412
20056
200610
200710
200811
20098
20108
201120
20126
20136
20149
20159
20168
201712
20188
20196
202014
20215
20221


2016 Biomedical Engineering Society: Fellow
2015 Boston University School of Medicine: Evans Center Research Collaborator Award
2015 Annual meeting of the Brazilian Physiology Society: Invited plenary talk
2014 Japanese Mechanobiology Meeting, Okayama: Invited plenary lecturer
2013 annual meeting of the Japanese Respiratory Society, Tokyo: Invited plenary lecturer
2007 American Institute for Medical and Biological Engineering: Fellow
2007 Boston University: Elected Biomedical Engineering Professor of the Year
Contact for Mentoring:

44 Cummington St
Boston MA 02215
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