J. Michael Gaziano, MD
Adjunct Professor
Boston University Chobanian & Avedisian School of Medicine
Medicine
Cardiovascular Medicine

MD, Yale University School of Medicine
MPH, Harvard School of Public Health
BA, West Virginia University



Dr. Michael J. Gaziano, MD, MPH is an internationally recognized chronic disease epidemiologist and trialist. He received his MD from Yale Medical School and his MPH from the Harvard School of Public Health.

At the VA Boston Healthcare System, he is one of the Director the Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC), a national epidemiology and trial center funded by CSR&D where he directs the epidemiology research center. He is national PI for the Million Veteran Program (MVP), a large project designed to enroll a million veterans into a large observational cohort with stored biospecimens. He also serves as the director of the Boston Geriatric Research and Education Center (GRECC). At VA Boston he runs a preventive cardiology program with an associated fellowship. He is the Chief of the Division of Aging at Brigham and Women’s Hospital where he is principal investigator for the ongoing Physicians' Health Study (PHS) II study, a large-scale trial of vitamins in the prevention of chronic disease. The Physicians’ Health Study cohort is comprised of 29,000 physicians who have been followed for up to 28 years. He is a Professor of Medicine at Harvard Medical School.

Dr. Gaziano’s research interests include the epidemiology of chronic diseases, with a particular interest in the roles that individual lifestyle choices (diet, exercise, smoking), metabolic factors (obesity, high cholesterol, and hypertension), and biochemical and genetic markers play on the risk of coronary artery disease and stroke. Also of interest is the impact that vascular disease has on other organ systems. Recently, Dr. Gaziano has initiated a number of research projects to investigate the diverse nature of atherosclerosis. While atherosclerosis plaques form only in certain large and medium-sized vessels, the process of atherogenesis affects arteries of all sizes. For example, renal dysfunction, cognitive decline and osteoporosis-related fractures have been linked to various cardiovascular disease risk factors, suggesting a role for small vessel disease in vascular dementia, in abnormal bone remodeling and chronic renal disease. These projects are intended to explore the extent to which atherosclerotic disease in small vessels leads to these and other chronic conditions.

He has published over 350 original reports, reviews, book chapters, and books. He teaches advanced epidemiology and has mentored over 50 trainees. He is a contributing editor for JAMA.

VA Boston Healthcare System






Title
Physicians Health Study II: Prevention Trial of Vitamins
(PI)

Genomics of Posttraumatic Stress Disorder in Veterans
(PI)

Influenza Vaccine to Effectively Stop Cardio-thoracic Events and Decompensated Heart Failure (INVESTED)
(PI)

The Million Veteran Program (MVP) R&D#10286-C
(PI)

CSP Epidemiology Research and Information Center (ERIC)
(PI)

Veteran Genetics and Health Referent Cohort
(PI)



Yr Title Project-Sub Proj Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. Wang L, Cook NR, Manson JAE, Gaziano JM, Buring JE, Sesso HD. Associations Of Vitamin D-Related Biomarkers With Hypertension And The Renin-Angiotensin System In Men And Women. Am J Hypertens. 2024 Aug 09.View Related Profiles. PMID: 39120701
     
  2. Elmore AR, Adhikari N, Hartley AE, Aparicio HJ, Posner DC, Hemani G, Tilling K, Gaunt TR, Wilson PWF, Casas JP, Gaziano JM, Davey Smith G, Paternoster L, Cho K, Peloso GM. Protein Identification for Stroke Progression via Mendelian Randomization in Million Veteran Program and UK Biobank. Stroke. 2024 Aug; 55(8):2045-2054.View Related Profiles. PMID: 39038097; PMCID: PMC11259242; DOI: 10.1161/STROKEAHA.124.047103;
     
  3. Verma A, Huffman JE, Rodriguez A, Conery M, Liu M, Ho YL, Kim Y, Heise DA, Guare L, Panickan VA, Garcon H, Linares F, Costa L, Goethert I, Tipton R, Honerlaw J, Davies L, Whitbourne S, Cohen J, Posner DC, Sangar R, Murray M, Wang X, Dochtermann DR, Devineni P, Shi Y, Nandi TN, Assimes TL, Brunette CA, Carroll RJ, Clifford R, Duvall S, Gelernter J, Hung A, Iyengar SK, Joseph J, Kember R, Kranzler H, Kripke CM, Levey D, Luoh SW, Merritt VC, Overstreet C, Deak JD, Grant SFA, Polimanti R, Roussos P, Shakt G, Sun YV, Tsao N, Venkatesh S, Voloudakis G, Justice A, Begoli E, Ramoni R, Tourassi G, Pyarajan S, Tsao P, O'Donnell CJ, Muralidhar S, Moser J, Casas JP, Bick AG, Zhou W, Cai T, Voight BF, Cho K, Gaziano JM, Madduri RK, Damrauer S, Liao KP. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science. 2024 Jul 19; 385(6706):eadj1182.View Related Profiles. PMID: 39024449
     
  4. Madenci AL, Kurgansky KE, Dickerman BA, Gerlovin H, Wanis KN, Smith AD, Trinqart L, Gagnon DR, Cho K, Gaziano JM, Casas JP, Robins JM, Hernán MA. Estimating the Effect of Bariatric Surgery on Cardiovascular Events Using Observational Data? Epidemiology. 2024 Sep 01; 35(5):721-729.View Related Profiles. PMID: 39024034
     
  5. Goryachev SD, Yildirim C, DuMontier C, La J, Dharne M, Gaziano JM, Brophy MT, Munshi NC, Driver JA, Do NV, Fillmore NR. Natural Language Processing Algorithm to Extract Multiple Myeloma Stage From Oncology Notes in the Veterans Affairs Healthcare System. JCO Clin Cancer Inform. 2024 Jul; 8:e2300197.View Related Profiles. PMID: 39038255
     
  6. Neale ZE, Fonda JR, Miller MW, Wolf EJ, Zhang R, Sherva R, Harrington KM, Merritt V, Panizzon MS, Hauger RL, Gaziano JM, Logue MW. Subjective cognitive concerns, APOE e4, PTSD symptoms, and risk for dementia among older veterans. Alzheimers Res Ther. 2024 Jun 29; 16(1):143.View Related Profiles. PMID: 38951900; PMCID: PMC11218206; DOI: 10.1186/s13195-024-01512-w;
     
  7. Sun YV, Liu C, Hui Q, Zhou JJ, Gaziano JM, Wilson PWF, Joseph J, Phillips LS. Identification and correction for collider bias in a genome-wide association study of diabetes-related heart failure. Am J Hum Genet. 2024 Jul 11; 111(7):1481-1493. PMID: 38897203; PMCID: PMC11267521; DOI: 10.1016/j.ajhg.2024.05.018;
     
  8. Ni Z, Kundu P, McKean DF, Wheeler W, Albanes D, Andreotti G, Antwi SO, Arslan AA, Bamlet WR, Beane Freeman LE, Berndt SI, Bracci PM, Brennan P, Buring JE, Chanock SJ, Gallinger S, Gaziano JM, Giles GG, Giovannucci EL, Goggins MG, Goodman PJ, Haiman CA, Hassan MM, Holly EA, Hung RJ, Katzke V, Kooperberg C, Kraft P, Le Marchand L, Li D, McCullough ML, Milne RL, Moore SC, Neale RE, Oberg AL, Patel AV, Peters U, Rabe KG, Risch HA, Shu XO, Smith Byrne K, Visvanathan K, Wactawski-Wende J, White E, Wolpin BM, Yu H, Zeleniuch-Jacquotte A, Zheng W, Zhong J, Amundadottir LT, Stolzenberg-Solomon RZ, Klein AP. Genome-wide analysis to assess if heavy alcohol consumption modifies the association between SNPs and pancreatic cancer risk. Cancer Epidemiol Biomarkers Prev. 2024 Jun 13.View Related Profiles. PMID: 38869494
     
  9. Gelernter J, Levey DF, Galimberti M, Harrington K, Zhou H, Adhikari K, Gupta P, Gaziano JM, Eliott D, Stein MB. Genome-wide association study of the common retinal disorder epiretinal membrane: Significant risk loci in each of three American populations. Cell Genom. 2024 Jun 12; 4(6):100582.View Related Profiles. PMID: 38870908; PMCID: PMC11228954; DOI: 10.1016/j.xgen.2024.100582;
     
  10. Pagadala MS, Lui A, Lynch J, Karunamuni R, Lee KM, Plym A, Rose BS, Carter H, Kibel AS, DuVall SL, Vassy J, Gaziano JM, Panizzon MS, Hauger RL, Seibert TM. Healthy lifestyle and prostate cancer risk in the Million Veteran Program. Cancer. 2024 Jun 12.View Related Profiles. PMID: 38865417
     
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