J. Michael Gaziano, MD
Adjunct Professor
Boston University School of Medicine
Dept of Medicine
Cardiovascular Medicine

MD, Yale University School of Medicine
MPH, Harvard School of Public Health

Dr. Michael J. Gaziano, MD, MPH is an internationally recognized chronic disease epidemiologist and trialist. He received his MD from Yale Medical School and his MPH from the Harvard School of Public Health.

At the VA Boston Healthcare System, he is one of the Director the Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC), a national epidemiology and trial center funded by CSR&D where he directs the epidemiology research center. He is national PI for the Million Veteran Program (MVP), a large project designed to enroll a million veterans into a large observational cohort with stored biospecimens. He also serves as the director of the Boston Geriatric Research and Education Center (GRECC). At VA Boston he runs a preventive cardiology program with an associated fellowship. He is the Chief of the Division of Aging at Brigham and Women’s Hospital where he is principal investigator for the ongoing Physicians' Health Study (PHS) II study, a large-scale trial of vitamins in the prevention of chronic disease. The Physicians’ Health Study cohort is comprised of 29,000 physicians who have been followed for up to 28 years. He is a Professor of Medicine at Harvard Medical School.

Dr. Gaziano’s research interests include the epidemiology of chronic diseases, with a particular interest in the roles that individual lifestyle choices (diet, exercise, smoking), metabolic factors (obesity, high cholesterol, and hypertension), and biochemical and genetic markers play on the risk of coronary artery disease and stroke. Also of interest is the impact that vascular disease has on other organ systems. Recently, Dr. Gaziano has initiated a number of research projects to investigate the diverse nature of atherosclerosis. While atherosclerosis plaques form only in certain large and medium-sized vessels, the process of atherogenesis affects arteries of all sizes. For example, renal dysfunction, cognitive decline and osteoporosis-related fractures have been linked to various cardiovascular disease risk factors, suggesting a role for small vessel disease in vascular dementia, in abnormal bone remodeling and chronic renal disease. These projects are intended to explore the extent to which atherosclerotic disease in small vessels leads to these and other chronic conditions.

He has published over 350 original reports, reviews, book chapters, and books. He teaches advanced epidemiology and has mentored over 50 trainees. He is a contributing editor for JAMA.

VA Boston Healthcare System

Physicians Health Study II: Prevention Trial of Vitamins
Genomics of Posttraumatic Stress Disorder in Veterans
Influenza Vaccine to Effectively Stop Cardio-thoracic Events and Decompensated Heart Failure (INVESTED)
The Million Veteran Program (MVP) R&D#10286-C
CSP Epidemiology Research and Information Center (ERIC)
Veteran Genetics and Health Referent Cohort

Yr Title Project-Sub Proj Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. Juraschek SP, Gaziano JM, Glynn RJ, Gomelskaya N, Bubes VY, Buring JE, Shmerling RH, Sesso HD. Effects of vitamin C supplementation on gout risk: results from the physicians' health study II trial. Am J Clin Nutr. 2022 May 16.View Related Profiles. PMID: 35575611
  2. Orkaby AR, Ward R, Chen J, Shanbhag A, Sesso HD, Gaziano JM, Djousse L, Driver JA. Influence of Long-term Nonaspirin NSAID Use on Risk of Frailty in Men =60 Years: The Physicians' Health Study. J Gerontol A Biol Sci Med Sci. 2022 05 05; 77(5):1048-1054. PMID: 35018441; PMCID: PMC9071430; DOI: 10.1093/gerona/glac006;
  3. Verma A, Tsao NL, Thomann LO, Ho YL, Iyengar SK, Luoh SW, Carr R, Crawford DC, Efird JT, Huffman JE, Hung A, Ivey KL, Levin MG, Lynch J, Natarajan P, Pyarajan S, Bick AG, Costa L, Genovese G, Hauger R, Madduri R, Pathak GA, Polimanti R, Voight B, Vujkovic M, Zekavat SM, Zhao H, Ritchie MD, Chang KM, Cho K, Casas JP, Tsao PS, Gaziano JM, O'Donnell C, Damrauer SM, Liao KP. A Phenome-Wide Association Study of genes associated with COVID-19 severity reveals shared genetics with complex diseases in the Million Veteran Program. PLoS Genet. 2022 Apr; 18(4):e1010113.View Related Profiles. PMID: 35482673; PMCID: PMC9049369; DOI: 10.1371/journal.pgen.1010113;
  4. Seligman B, Charest B, Ho YL, Gerlovin H, Ward RE, Cho K, Driver JA, Gaziano JM, Gagnon DR, Orkaby AR. 30-day mortality following COVID-19 and influenza hospitalization among US veterans aged 65 and older. J Am Geriatr Soc. 2022 Apr 26.View Related Profiles. PMID: 35474510
  5. Whitbourne SB, Nguyen XT, Song RJ, Lord E, Lyden M, Harrington KM, Ward R, Li Y, Brewer JVV, Cho KM, Djousse L, Muralidhar S, Tsao PS, Gaziano JM, Casas JP. Million Veteran Program's response to COVID-19: Survey development and preliminary findings. PLoS One. 2022; 17(4):e0266381.View Related Profiles. PMID: 35468170; PMCID: PMC9037905; DOI: 10.1371/journal.pone.0266381;
  6. Velagaleti RS, Vetter J, Parker R, Kurgansky KE, Sun YV, Djousse L, Gaziano JM, Gagnon D, Joseph J. Change in Left Ventricular Ejection Fraction With Coronary Artery Revascularization and Subsequent Risk for Adverse Cardiovascular Outcomes. Circ Cardiovasc Interv. 2022 Apr; 15(4):e011284.View Related Profiles. PMID: 35411780
  7. Hung AM, Shah SC, Bick AG, Yu Z, Chen HC, Hunt CM, Wendt F, Wilson O, Greevy RA, Chung CP, Suzuki A, Ho YL, Akwo E, Polimanti R, Zhou J, Reaven P, Tsao PS, Gaziano JM, Huffman JE, Joseph J, Luoh SW, Iyengar S, Chang KM, Casas JP, Matheny ME, O'Donnell CJ, Cho K, Tao R, Susztak K, Robinson-Cohen C, Tuteja S, Siew ED. APOL1 Risk Variants, Acute Kidney Injury, and Death in Participants With African Ancestry Hospitalized With COVID-19 From the Million Veteran Program. JAMA Intern Med. 2022 Apr 01; 182(4):386-395.View Related Profiles. PMID: 35089317
  8. Imran TF, Mohebali D, Lopez D, Goli RR, DeFilippis EM, Truong S, Bello NA, Gaziano JM, Djousse L, Coglianese EE, Feinberg L, Wu WC, Choudhary G, Arany Z, Kociol R, Sabe MA. NT-proBNP and predictors of event free survival and left ventricular systolic function recovery in peripartum cardiomyopathy. Int J Cardiol. 2022 Jun 15; 357:48-54. PMID: 35358637
  9. Wang DD, Li Y, Nguyen XT, Song RJ, Ho YL, Hu FB, Willett WC, Wilson PWF, Cho K, Gaziano JM, Djoussé L. Degree of Adherence to Based Diet and Total and Cause-Specific Mortality: Prospective Cohort Study in the Million Veteran Program. Public Health Nutr. 2022 Mar 21; 1-38. PMID: 35307047
  10. Djoussé L, Cook NR, Kim E, Walter J, Al-Ramady OT, Luttmann-Gibson H, Albert CM, Mora S, Buring JE, Gaziano JM, Manson JE. Diabetes Mellitus, Race, and Effects of Omega-3 Fatty Acids on Incidence of Heart Failure Hospitalization. JACC Heart Fail. 2022 Apr; 10(4):227-234.View Related Profiles. PMID: 35361440; PMCID: PMC8986092; DOI: 10.1016/j.jchf.2021.12.006;
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