J. Michael Gaziano, MD
Adjunct Professor
Boston University Chobanian & Avedisian School of Medicine
Cardiovascular Medicine

MD, Yale University School of Medicine
MPH, Harvard School of Public Health
BA, West Virginia University

Dr. Michael J. Gaziano, MD, MPH is an internationally recognized chronic disease epidemiologist and trialist. He received his MD from Yale Medical School and his MPH from the Harvard School of Public Health.

At the VA Boston Healthcare System, he is one of the Director the Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC), a national epidemiology and trial center funded by CSR&D where he directs the epidemiology research center. He is national PI for the Million Veteran Program (MVP), a large project designed to enroll a million veterans into a large observational cohort with stored biospecimens. He also serves as the director of the Boston Geriatric Research and Education Center (GRECC). At VA Boston he runs a preventive cardiology program with an associated fellowship. He is the Chief of the Division of Aging at Brigham and Women’s Hospital where he is principal investigator for the ongoing Physicians' Health Study (PHS) II study, a large-scale trial of vitamins in the prevention of chronic disease. The Physicians’ Health Study cohort is comprised of 29,000 physicians who have been followed for up to 28 years. He is a Professor of Medicine at Harvard Medical School.

Dr. Gaziano’s research interests include the epidemiology of chronic diseases, with a particular interest in the roles that individual lifestyle choices (diet, exercise, smoking), metabolic factors (obesity, high cholesterol, and hypertension), and biochemical and genetic markers play on the risk of coronary artery disease and stroke. Also of interest is the impact that vascular disease has on other organ systems. Recently, Dr. Gaziano has initiated a number of research projects to investigate the diverse nature of atherosclerosis. While atherosclerosis plaques form only in certain large and medium-sized vessels, the process of atherogenesis affects arteries of all sizes. For example, renal dysfunction, cognitive decline and osteoporosis-related fractures have been linked to various cardiovascular disease risk factors, suggesting a role for small vessel disease in vascular dementia, in abnormal bone remodeling and chronic renal disease. These projects are intended to explore the extent to which atherosclerotic disease in small vessels leads to these and other chronic conditions.

He has published over 350 original reports, reviews, book chapters, and books. He teaches advanced epidemiology and has mentored over 50 trainees. He is a contributing editor for JAMA.

VA Boston Healthcare System

Physicians Health Study II: Prevention Trial of Vitamins

Genomics of Posttraumatic Stress Disorder in Veterans

Influenza Vaccine to Effectively Stop Cardio-thoracic Events and Decompensated Heart Failure (INVESTED)

The Million Veteran Program (MVP) R&D#10286-C

CSP Epidemiology Research and Information Center (ERIC)

Veteran Genetics and Health Referent Cohort

Yr Title Project-Sub Proj Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. Hung AM, Assimon VA, Chen HC, Yu Z, Vlasschaert C, Triozzi JL, Chan H, Wheless L, Wilson O, Shah SC, Mack T, Thompson T, Matheny ME, Chandrasekar S, Mozaffari SV, Chung CP, Tsao P, Susztak K, Siew ED, Estrada K, Gaziano JM, Graham RR, Tao R, Hoek M, Robinson-Cohen C, Green EM, Bick AG. Genetic Inhibition of APOL1 Pore-Forming Function Prevents APOL1-Mediated Kidney Disease. J Am Soc Nephrol. 2023 Oct 06. PMID: 37798822
  2. Austin-Zimmerman I, Levey DF, Giannakopoulou O, Deak JD, Galimberti M, Adhikari K, Zhou H, Denaxas S, Irizar H, Kuchenbaecker K, McQuillin A, Concato J, Buysse DJ, Gaziano JM, Gottlieb DJ, Polimanti R, Stein MB, Bramon E, Gelernter J. Genome-wide association studies and cross-population meta-analyses investigating short and long sleep duration. Nat Commun. 2023 Sep 28; 14(1):6059. PMID: 37770476; PMCID: PMC10539313; DOI: 10.1038/s41467-023-41249-y;
  3. King SD, Veliginti S, Brouwers MCGJ, Ren Z, Zheng W, Setiawan VW, Wilkens LR, Shu XO, Arslan AA, Beane Freeman LE, Bracci PM, Canzian F, Du M, Gallinger SJ, Giles GG, Goodman PJ, Haiman CA, Kogevinas M, Kooperberg C, LeMarchand L, Neale RE, Visvanathan K, White E, Albanes D, Andreotti G, Babic A, Berndt SI, Brais LK, Brennan P, Buring JE, Rabe KG, Bamlet WR, Chanock SJ, Fuchs CS, Gaziano JM, Giovannucci EL, Hackert T, Hassan MM, Katzke V, Kurtz RC, Lee IM, Malats N, Murphy N, Oberg AL, Orlow I, Porta M, Real FX, Rothman N, Sesso HD, Silverman DT, Thompson IM, Wactawski-Wende J, Wang X, Wentzensen N, Yu H, Zeleniuch-Jacquotte A, Yu K, Wolpin BM, Duell EJ, Li D, Hung RJ, Perdomo S, McCullough ML, Freedman ND, Patel AV, Peters U, Riboli E, Sund M, Tjønneland A, Zhong J, Van Den Eeden SK, Kraft P, Risch HA, Amundadottir LT, Klein AP, Stolzenberg-Solomon RZ, Antwi SO. Genetic Susceptibility to Nonalcoholic Fatty Liver Disease and Risk for Pancreatic Cancer: Mendelian Randomization. Cancer Epidemiol Biomarkers Prev. 2023 Sep 01; 32(9):1265-1269.View Related Profiles. PMID: 37351909; PMCID: PMC10529823; DOI: 10.1158/1055-9965.EPI-23-0453;
  4. DuMontier C, La J, Bihn J, Corrigan J, Yildirim C, Dharne M, Hassan H, Yellapragada SV, Abel GA, Gaziano JMM, Do NV, Brophy MT, Kim DH, Munshi NC, Fillmore NR, Driver JA. More intensive therapy as more effective treatment for frail patients with multiple myeloma. Blood Adv. 2023 Aug 15.View Related Profiles. PMID: 37582048
  5. Qavi AH, Zhou G, Ward RE, Carr JJ, Ellison RC, Arnett DK, Gaziano JM, Djousse L. Association of potato consumption with calcified atherosclerotic plaques in the coronary arteries: The NHLBI Family Heart Study. Nutr Metab Cardiovasc Dis. 2023 Jul 25. PMID: 37580232
  6. Ivey KL, Nguyen XT, Li R, Furtado J, Cho K, Gaziano JM, Hu FB, Willett WC, Wilson PW, Djoussé L. Association of dietary fatty acids with the risk of atherosclerotic cardiovascular disease in a prospective cohort of United States veterans. Am J Clin Nutr. 2023 Oct; 118(4):763-772. PMID: 37479185
  7. Rasooly D, Peloso GM, Pereira AC, Dashti H, Giambartolomei C, Wheeler E, Aung N, Ferolito BR, Pietzner M, Farber-Eger EH, Wells QS, Kosik NM, Gaziano L, Posner DC, Bento AP, Hui Q, Liu C, Aragam K, Wang Z, Charest B, Huffman JE, Wilson PWF, Phillips LS, Whittaker J, Munroe PB, Petersen SE, Cho K, Leach AR, Magariños MP, Gaziano JM, Langenberg C, Sun YV, Joseph J, Casas JP. Genome-wide association analysis and Mendelian randomization proteomics identify drug targets for heart failure. Nat Commun. 2023 Jul 10; 14(1):3826.View Related Profiles. PMID: 37429843; PMCID: PMC10333277; DOI: 10.1038/s41467-023-39253-3;
  8. Ross JM, Sugimoto JD, Timmons A, Adams J, Deardoff K, Korpak A, Liu C, Moore K, Wilson D, Bedimo R, Chang KM, Cho K, Crothers K, Garshick E, Gaziano JM, Holodniy M, Hunt CM, Isaacs SN, Le E, Jones BE, Shah JA, Smith NL, Lee JS. Early Outcomes of SARS-CoV-2 Infection in a Multisite Prospective Cohort of Inpatient Veterans. Open Forum Infect Dis. 2023 Jul; 10(7):ofad330.View Related Profiles. PMID: 37484899; PMCID: PMC10358428; DOI: 10.1093/ofid/ofad330;
  9. Guardino ET, Li Y, Nguyen XM, Wilson PWF, Gaziano JM, Cho K, Benjamin EJ, Djoussé L. Dietary ?-3 fatty acids and the incidence of atrial fibrillation in the Million Veteran Program. Am J Clin Nutr. 2023 Aug; 118(2):406-411.View Related Profiles. PMID: 37353210; PMCID: PMC10447488; DOI: 10.1016/j.ajcnut.2023.06.001;
  10. Lui AJ, Pagadala MS, Zhong AY, Lynch J, Karunamuni R, Lee KM, Plym A, Rose BS, Carter H, Kibel AS, DuVall SL, Gaziano JM, Panizzon MS, Hauger RL, Seibert TM. Agent Orange exposure and prostate cancer risk in the Million Veteran Program. medRxiv. 2023 Jun 16. PMID: 37398205; PMCID: PMC10312838; DOI: 10.1101/2023.06.14.23291413;
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