Michael F. Holick, MD, PhD
Boston University School of Medicine
Dept of Medicine
Endocrinology, Diabetes, Nutrition & Weight Management

MD, University of Wisconsin Madison
PhD, University of Wisconsin Madison
MS, University of Wisconsin Madison

Dr. Holick has made numerous contributions to the field of the biochemistry, physiology, metabolism, and photobiology of vitamin D for human nutrition. Dr. Holick has established global recommendations advising sunlight exposure as an integral source of vitamin D. He has helped increase awareness in the pediatric and medical communities regarding vitamin D deficiency pandemic, and its role in causing not only metabolic bone disease, and osteoporosis in adults, but increasing risk of children and adults developing preeclampsia, common deadly cancers, schizophrenia, infectious diseases including TB and influenza, autoimmune diseases including type 1 diabetes and multiple sclerosis, type 2 diabetes, stroke and heart disease.

Dr. Holick is a Diplomate of the American Board of Internal Medicine, a Fellow of the American College of Nutrition, and a member of the American Association of Physicians. He is the recipient of numerous awards and honors, including the General Clinical Research Centers Program Award for Excellence in Clinical Research from NIH, American College of Nutrition’s Communication Media Award, Best Docs in America, the Linus Pauling Functional Medicine Award from the Institute for Functional Medicine and the Linus Pauling Prize for Human Nutrition. Dr. Holick serves on a number of national committees and editorial boards and has organized and/or co-chaired several international symposia. He served as the chair for the Endocrine Society’s Practice Guidelines on Vitamin D. He has authored more than 400 peer-reviewed publications, and written more than 200 review articles, as well as numerous book chapters. He has acted as editor and/or co-editor on 13 books, and has written The UV Advantage in 2004 and The Vitamin D Solution in 2010 and helped develop the dminder.info app.

Boston University School of Medicine
Physiology & Biophysics

Boston University
Evans Center for Interdisciplinary Biomedical Research

Graduate Faculty (Primary Mentor of Grad Students)
Boston University School of Medicine, Graduate Medical Sciences

Boston University Medical Campus
General Clinical Research Unit

Boston Medical Center
Bone Health Care Clinic

Director of the Vitamin D, Skin and Bone Research Laboratory
Boston University School of Medicine
Endocrinology, Diabetes, Nutrition & Weight Management

2020 Boston Magazine : Boston’s Magazine Top Doc – Endocrinology, Diabetes, and Weight Management
2019 Expertscape #1 Worldwide Expert in Vitamin D Deficiency
2019 American Journal of Epidemiology & Society for Epidemiologic Research 2018 Article of the Year: “Di
2019 Expertscape #1 Worldwide Expert in Sunlight
2019 Orthomolecular Medicine Hall of Fame
2019 Fellow American Society of Clinical Nutrition
2017 PLOS ONE top 25% most cited article “Temporal relationship between vitamin D status and PTH in the
2017 PLOS ONE top 10% most cited article “Influence of Vitamin D Status and Vitamin D3 Supplementation
2016-2019 Americas Top Doctors: America's Top Doctors
2016 American Registry “Best of the Best”
2015 EVIDAS: Honorary Award for the Outstanding Contribution to the Development of Knowledge and Dissemination of
2014 Boston University School of Medicine: Educator of the Year in Graduate Medical Sciences, Master’s Degree Programs
2014 America’s Top Physicians Award
2014 Thomas Reuters World’s Most Influential Scientific Minds, Clinical Medicine
2014 American Society for Bone and Mineral Research : Louis Avioli Award
2014 American Association of Clinical Chemistry’s Outstanding Speaker Award
2013 Top 10 Doctor Award
2012 Boston University Admissions Committee: Distinguished Service Award
2011 Boston Magazine : Top Docs in Endocrinology
2011 Clark T. Sawin Memorial Lecture, The Endocrine Society: Delbert A. Fisher Research Scholar
2011 American College of Nutrition’s Communication Media Award
2011-2015 Castle Connolly : Best Doctors in America
2010 The Chester S. Keefer MD Society
2010 AACC New York Metro Section: 2010 Van Slyke Award
2010 AACC Outstanding Speaker Award for 2010
2009 The Linus Pauling Institute 2009 Diet & Optimum Health Conference Portland OR: Linus Pauling Prize and Lecture: A D-Lightful Vitamin for Health
2009 The North American Menopause Society: NAMS/Upsher-Smith Laboratories, Inc. Vitamin D Research Award
2009 19th International Congress of Nutrition, Bangkok, Thailand: DSM Innovation in Nutrition Award
2009 AACC Outstanding Speaker Award for 2009
2008 24th Annual Rheumatology on the Beach, San Destin FL: Outstanding Speaker Award Arthritis Foundation (AL Chapter) Featured Speaker
2007 The Institute for Functional Medicine: Linus Pauling Functional Medicine Award
2007 CSEM Eli Lilly Award Lecture
2006 Annual General Clinical Research Centers Program Award for Excellence in Clinical Research
2006-2016 Boston’s Magazine Top Doc – Endocrinology, Diabetes, and Weight Management
2003 American Society for Clinical Nutrition: Robert H. Herman Memorial Award in Clinical Nutrition
2002 American College of Nutrition: ACN Award
2001 Boston Magazine: Top Docs for Women
2000 American Skin Associations: Psoriasis Research Achievement Award
1994 American Society for Clinical Nutrition: McCollum Award
1991 Osborne and Mendel Award
1989 Arnold-Rickle Prize for Research in UV Radiation and Vitamin D Metabolism
1986 Seton Hall University: Stanley S. Bergen Award for Excellence in the Medical Field
1986 National Institutes of Health: Merit Award
1985 Pisa Medallion for Excellence in Science
1983 American Institute of Nutrition: Mead Johnson Award
1981 Ten Outstanding Young Leaders Award
1980 Fuller Albright Young Investigator Award
1974 University of Wisconsin, Madison WI: Charles Busch Award
1972 M.D. Anderson Hospital: Wilson S. Stone Memorial Award
1971 American Oil Chemists Society: Honored Student Award

Pilot clinical trial to evaluate the pharmacokinetics of orally administered 25-hydroxyvitamin D3 and vitamin D3 in healthy adults and adults with a history of intestinal malabsorption
11/26/2018 - 11/26/2022 (PI)

Master Clinical Research Services and Clinical Trial Agreement- CGAM
09/27/2017 - 09/30/2022 (PI)

PARADIGHM (Physicians Advancing Disease Knowledge in Hypoparathyroidism): A Natural History Registry for Patients with Chronic Hypoparathyroidism
07/13/2015 - 07/12/2016 (PI)
Shire, Inc.

A Randomized, Double-blind, Active-controlled Study to Evaluate the Efficacy and Safety of Denosumab Compared with Risedronate in Glucocoticoid-treated individuals
02/28/2014 - 02/27/2016 (PI)
Amgen, Inc.

Impact of Vitamin D Dose on Vitamin D Status and Cardiometabolic Risk in School Children Living in Northern Latitudes
06/01/2011 - 03/31/2015 (Subcontract PI)
Trustees of Tufts College, Inc NIH NHLBI

Race/Ethnic Disparities in Makers of Fall Risk and Bone Strength Among Men
05/15/2009 - 04/30/2014 (Subcontract PI)
New England Research Institutes NIH NIA

Pre-Clinical and Clinical Investigations on UV Irradiated Mushrooms: The Vitamin D Connection
04/01/2011 - 12/31/2013 (PI)
Mushroom Council

Vitamin D Status of Malian children with moderate and acute malnutrition
05/01/2012 - 04/30/2013 (PI)
International Nutrition Foundation

A Phase III Randomized, Placebo-Controlled Clinical Trial to Assess the Safety & Efficacy of Odanacatib (MK-0822) to Reduce the Risk of Fracture in Osteoporotic Postmenopausal Women Treated with
01/20/2009 - 01/20/2013 (PI)
Merck & Company, Inc.

Vitamin D Status, Pneumonia and Growth in a Pediatric Andean Population
01/13/2012 - 01/12/2013 (PI)
Sight & Life Foundation

Showing 10 of 25 results. Show All Results


Yr Title Project-Sub Proj Pubs
2012 Addressing Alcohol/HIV Consequences in Substance Dependence - Boston ARCH Cohort 5U01AA020784-02 10
2011 Addressing Alcohol/HIV Consequences in Substance Dependence - Boston ARCH Cohort 1U01AA020784-01 10
2011 Impact of vitamin D supplementation on cardiometabolic risk in schoolchildren 1R01HL106160-01 10
2006 PTH (7-34) for Chemotherapy alopecia in Breast Cancer 1R41CA119802-01
Showing 10 of 69 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Maghbooli Z, Sahraian MA, Jamali-Moghadam SR, Asadi A, Azadeh Zarei MD, Zendehdel A, Varzandi T, Mohammadnabi S, Alijani N, Karimi M, Shirvani A, Holick MF. Treatment with 25-hydroxyvitamin D3 (calcifediol) is associated with a reduction in the blood neutrophil-to-lymphocyte ratio marker of disease severity in patients hospitalized with COVID-19: a pilot, multicenter, randomized, placebo-controlled double blind clinical trial. Endocr Pract. 2021 Oct 12. PMID: 34653608; PMCID: PMC8511889; DOI: 10.1016/j.eprac.2021.09.016;
  2. Martín Giménez VM, Lahore H, Ferder L, Holick MF, Manucha W. The little-explored therapeutic potential of nanoformulations of 1,25-dihydroxyvitamin D3 and its active analogs in prevalent inflammatory and oxidative disorders. Nanomedicine (Lond). 2021 Oct 06. PMID: 34610750
  3. Charoenngam N, Kalajian TA, Shirvani A, Yoon GH, Desai S, McCarthy A, Apovian CM, Holick MF. Reply to S Minisola et al. Am J Clin Nutr. 2021 09 01; 114(3):1252-1253.View Related Profiles. PMID: 34467971
  4. Charoenngam N, Kalajian TA, Shirvani A, Yoon GH, Desai S, McCarthy A, Apovian CM, Holick MF. A pilot-randomized, double-blind crossover trial to evaluate the pharmacokinetics of orally administered 25-hydroxyvitamin D3 and vitamin D3 in healthy adults with differing BMI and in adults with intestinal malabsorption. Am J Clin Nutr. 2021 09 01; 114(3):1189-1199.View Related Profiles. PMID: 34008842; PMCID: PMC8408845; DOI: 10.1093/ajcn/nqab123;
  5. Charoenngam N, Alexanian SM, Apovian CM, Holick MF. Association between Hyperglycemia at Hospital Presentation and Hospital Outcomes in COVID-19 Patients with and without Type 2 Diabetes: A Retrospective Cohort Study of Hospitalized Inner-City COVID-19 Patients. Nutrients. 2021 Jun 26; 13(7).View Related Profiles. PMID: 34206813; PMCID: PMC8308462; DOI: 10.3390/nu13072199;
  6. Holick MF, Shirvani A, Charoenngam N. Fetal Fractures in an Infant with Maternal Ehlers-Danlos Syndrome, CCDC134 Pathogenic Mutation and a Negative Genetic Test for Osteogenesis Imperfecta. Children (Basel). 2021 Jun 17; 8(6). PMID: 34204301; PMCID: PMC8235512; DOI: 10.3390/children8060512;
  7. Charoenngam N, Ilori TO, Holick MF, Hochberg NS, Apovian CM. Self-identified Race and COVID-19-Associated Acute Kidney Injury and Inflammation: a Retrospective Cohort Study of Hospitalized Inner-City COVID-19 Patients. J Gen Intern Med. 2021 Jun 07.View Related Profiles. PMID: 34100227; PMCID: PMC8183592; DOI: 10.1007/s11606-021-06931-1;
  8. Papadimitriou DT, Vassaras AK, Holick MF. Association between population vitamin D status and SARS-CoV-2 related serious-critical illness and deaths: An ecological integrative approach. World J Virol. 2021 May 25; 10(3):111-129. PMID: 34079693; PMCID: PMC8152454; DOI: 10.5501/wjv.v10.i3.111;
  9. Charoenngam N, Shirvani A, Reddy N, Vodopivec DM, Apovian CM, Holick MF. Authors' Reply: Vitamin D Sufficiency and COVID-19: Is Vitamin D Binding Protein (and Its Polymorphism) the Missing Link? Endocr Pract. 2021 06; 27(6):646-647.View Related Profiles. PMID: 33819635; PMCID: PMC8017947; DOI: 10.1016/j.eprac.2021.03.016;
  10. Charoenngam N, Shirvani A, Holick MF. Vitamin D and Its Potential Benefit for the COVID-19 Pandemic. Endocr Pract. 2021 May; 27(5):484-493.View Related Profiles. PMID: 33744444; PMCID: PMC7965847; DOI: 10.1016/j.eprac.2021.03.006;
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