Michael F. Holick, MD, PhD
Professor
Boston University School of Medicine
Dept of Medicine
Endocrinology, Diabetes, Nutrition & Weight Management

MD, University of Wisconsin Madison
PhD, University of Wisconsin Madison
MS, University of Wisconsin Madison




Dr. Holick has made numerous contributions to the field of the biochemistry, physiology, metabolism, and photobiology of vitamin D for human nutrition. Dr. Holick has established global recommendations advising sunlight exposure as an integral source of vitamin D. He has helped increase awareness in the pediatric and medical communities regarding vitamin D deficiency pandemic, and its role in causing not only metabolic bone disease, and osteoporosis in adults, but increasing risk of children and adults developing preeclampsia, common deadly cancers, schizophrenia, infectious diseases including TB and influenza, autoimmune diseases including type 1 diabetes and multiple sclerosis, type 2 diabetes, stroke and heart disease.

Dr. Holick is a Diplomate of the American Board of Internal Medicine, a Fellow of the American College of Nutrition, and a member of the American Association of Physicians. He is the recipient of numerous awards and honors, including the General Clinical Research Centers Program Award for Excellence in Clinical Research from NIH, American College of Nutrition’s Communication Media Award, Best Docs in America, the Linus Pauling Functional Medicine Award from the Institute for Functional Medicine and the Linus Pauling Prize for Human Nutrition. Dr. Holick serves on a number of national committees and editorial boards and has organized and/or co-chaired several international symposia. He served as the chair for the Endocrine Society’s Practice Guidelines on Vitamin D. He has authored more than 400 peer-reviewed publications, and written more than 200 review articles, as well as numerous book chapters. He has acted as editor and/or co-editor on 13 books, and has written The UV Advantage in 2004 and The Vitamin D Solution in 2010 and helped develop the dminder.info app.

Professor
Boston University School of Medicine
Physiology & Biophysics


Member
Boston University
Evans Center for Interdisciplinary Biomedical Research


Graduate Faculty (Primary Mentor of Grad Students)
Boston University School of Medicine, Graduate Medical Sciences


Director
Boston University Medical Campus
General Clinical Research Unit


Director
Boston Medical Center
Bone Health Care Clinic


Director of the Vitamin D, Skin and Bone Research Laboratory
Boston University School of Medicine
Medicine
Endocrinology, Diabetes, Nutrition & Weight Management



QR-TRP-039 - Evaluation of the Solius Device in the Increase in Vitamin D Levels in Subjects With Vitamin D Insufficiency or Deficiency
05/17/2021 - 05/17/2023 (Multi-PI)
PI: Michael F. Holick, MD, PhD
Solius


Evaluation of Florescent Labeled Vitamin D and Vitamin D Metabolites in Cultured Adipocites
03/01/2022 - 02/28/2023 (PI)
CARBOGEN AMCIS AG


Master Clinical Research Services and Clinical Trial Agreement- CGAM
09/27/2017 - 09/30/2022 (PI)
CARBOGEN AMCIS AG


Evaluation vitamin D and metabolites and fat storage
09/23/2021 - 12/31/2021 (PI)
CARBOGEN AMCIS AG


Pilot clinical trial to evaluate the pharmacokinetics of orally administered 25-hydroxyvitamin D3 and vitamin D3 in healthy adults and adults with a history of intestinal malabsorption
11/26/2018 - 11/26/2020 (PI)
CARBOGEN AMCIS AG


PARADIGHM (Physicians Advancing Disease Knowledge in Hypoparathyroidism): A Natural History Registry for Patients with Chronic Hypoparathyroidism
07/13/2015 - 07/12/2016 (PI)
Shire, Inc.


A Randomized, Double-blind, Active-controlled Study to Evaluate the Efficacy and Safety of Denosumab Compared with Risedronate in Glucocoticoid-treated individuals
02/28/2014 - 02/27/2016 (PI)
Amgen, Inc.


Impact of Vitamin D Dose on Vitamin D Status and Cardiometabolic Risk in School Children Living in Northern Latitudes
06/01/2011 - 03/31/2015 (Subcontract PI)
Trustees of Tufts College, Inc NIH NHLBI
5R01HL106160-04

Race/Ethnic Disparities in Makers of Fall Risk and Bone Strength Among Men
05/15/2009 - 04/30/2014 (Subcontract PI)
New England Research Institutes NIH NIA
5R01AG020727-08

Pre-Clinical and Clinical Investigations on UV Irradiated Mushrooms: The Vitamin D Connection
04/01/2011 - 12/31/2013 (PI)
Mushroom Council


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Title


Yr Title Project-Sub Proj Pubs
2012 Addressing Alcohol/HIV Consequences in Substance Dependence - Boston ARCH Cohort 5U01AA020784-02 10
2011 Addressing Alcohol/HIV Consequences in Substance Dependence - Boston ARCH Cohort 1U01AA020784-01 10
2011 Impact of vitamin D supplementation on cardiometabolic risk in schoolchildren 1R01HL106160-01 10
2008 BOSTON UNIVERSITY CLINICAL AND TRANSLATIONAL SCIENCE AWARD (CTSA) PROGRAM UL1 1UL1RR025771-01-5999 218
2008 GENERAL CLINICAL RESEARCH CENTER 5M01RR000533-40-7263 503
2007 PREVALENCE OF VITAMIN D DEFICIENCY IN PATIENTS ADMITTED TO REHABILITATION UNIT 2M01RR000533-39-8154 503
2006 PTH (7-34) for Chemotherapy alopecia in Breast Cancer 1R41CA119802-01
2006 BONE DENSITY IN AGING MEN OF DIVERSE RACE AND ETHNICITY 5M01RR000533-38-5574 503
2006 FLOOD LAMP ULTRAVIOLET RAYS AND VITAMIN D 5M01RR000533-38-5617 503
2006 PREVALENCE OF VITAMIN D DEFICIENCY IN PATIENTS ADMITTED TO REHABILITATION UNIT 5M01RR000533-38-5602 503
Showing 10 of 69 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Slominski AT, Kim TK, Slominski RM, Song Y, Janjetovic Z, Podgorska E, Reddy SB, Song Y, Raman C, Tang EKY, Fabisiak A, Brzeminski P, Sicinski RR, Atigadda V, Jetten AM, Holick MF, Tuckey RC. Metabolic activation of tachysterol3 to biologically active hydroxyderivatives that act on VDR, AhR, LXRs, and PPAR? receptors. FASEB J. 2022 Aug; 36(8):e22451. PMID: 35838947
     
  2. Charoenngam N, Ayoub D, Holick MF. Nutritional rickets and vitamin D deficiency: consequences and strategies for treatment and prevention. Expert Rev Endocrinol Metab. 2022 Jul 19; 1-14. PMID: 35852141
     
  3. Maghbooli Z, Mozaffari S, Dehghani Y, Rezaei Amirkiasar P, Malekhosseini AA, Rezanejad M, Holick MF. The lower basal metabolic rate is associated with increased risk of osteosarcopenia in postmenopausal women. BMC Womens Health. 2022 May 14; 22(1):171. PMID: 35568898; PMCID: PMC9107118; DOI: 10.1186/s12905-022-01754-6;
     
  4. Amon U, Yaguboglu R, Ennis M, Holick MF, Amon J. Safety Data in Patients with Autoimmune Diseases during Treatment with High Doses of Vitamin D3 According to the "Coimbra Protocol". Nutrients. 2022 Apr 10; 14(8). PMID: 35458137; PMCID: PMC9033096; DOI: 10.3390/nu14081575;
     
  5. Menéndez SG, Martín Giménez VM, Holick MF, Barrantes FJ, Manucha W. COVID-19 and neurological sequelae: Vitamin D as a possible neuroprotective and/or neuroreparative agent. Life Sci. 2022 May 15; 297:120464. PMID: 35271880; PMCID: PMC8898786; DOI: 10.1016/j.lfs.2022.120464;
     
  6. Holick MF. The CO-VID D-Lemma: A Call for Action. Nutrients. 2022 Feb 24; 14(5). PMID: 35267938; PMCID: PMC8912765; DOI: 10.3390/nu14050963;
     
  7. Bae JH, Choe HJ, Holick MF, Lim S. Association of vitamin D status with COVID-19 and its severity : Vitamin D and COVID-19: a narrative review. Rev Endocr Metab Disord. 2022 06; 23(3):579-599. PMID: 34982377; PMCID: PMC8724612; DOI: 10.1007/s11154-021-09705-6;
     
  8. Charoenngam N, Holick MF. Marked Underestimation of Serum 25-hydroxyvitamin D Concentrations by The Abbot Architect Chemiluminescent Microparticle Immunoassay in Patients Receiving Vitamin D2 Supplementation. Endocr Pract. 2022 Jan; 28(1):122-123. PMID: 34656785
     
  9. Maghbooli Z, Sahraian MA, Jamalimoghadamsiahkali S, Asadi A, Zarei A, Zendehdel A, Varzandi T, Mohammadnabi S, Alijani N, Karimi M, Shirvani A, Holick MF. Treatment With 25-Hydroxyvitamin D3 (Calcifediol) Is Associated With a Reduction in the Blood Neutrophil-to-Lymphocyte Ratio Marker of Disease Severity in Hospitalized Patients With COVID-19: A Pilot Multicenter, Randomized, Placebo-Controlled, Double-Blinded Clinical Trial. Endocr Pract. 2021 Dec; 27(12):1242-1251. PMID: 34653608; PMCID: PMC8511889; DOI: 10.1016/j.eprac.2021.09.016;
     
  10. Martín Giménez VM, Lahore H, Ferder L, Holick MF, Manucha W. The little-explored therapeutic potential of nanoformulations of 1,25-dihydroxyvitamin D3 and its active analogs in prevalent inflammatory and oxidative disorders. Nanomedicine (Lond). 2021 11; 16(26):2327-2330. PMID: 34610750
     
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