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Cassidy, MR., Sherburne, AC., Sheldon, HK., Gainsbury, ML., Gallant, JJ., Stucchi, AF., Becker, JM. . The Histone Deacetylase (HDAC) Inhibitor Valproic Acid (VPA) Decreases Postoperative Adhesions with One Intraoperative Dose. J Surg Res. 2012; 2(172):301-302; 2012..
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Cassidy, MR., Sheldon, HK., Gainsbury, ML., Kosaka, H., Stucchi, AF., Becker, JM. . The Role of the Neurokinin-1 Receptor in Adhesion Formation and Prevention. J Surg Res. 2012; 2(172):340; 2012..
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Esposito, A, Heydrick, S., Cassidy, MR, Gallant, J, Stucchi AF., Becker, JM. . A Neurokinin-1 Receptor Antagonist that Reduces Intraabdominal Adhesions Modulates Hypoxia Inducible Factor-1 Alpha and its Downstream Adhesiogenic Targets. J Surg Res. 2012; 2(172):340; 2012..
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Kosaka, H., Kantarci, A., Hasturk, H., Van Dyke, TE., Stucchi, AF., Becker, JM. . Resolvin E1 reduces intraabdominal adhesions by inhibiting macrophage chemoattraction into the peritoneum. J Surg Res. 2012; 2(172):340; 2012. .
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Gainsbury, ML., Sheldon, HK., Cassidy, MR., Chu, DI., Heydrick, S., Mitra, S., Stucchi, AF., Becker, JM. . The Angiotensin II Receptor Blocker (ARB) Losartan Decreases Post-operative Intraabdominal Adhesions by Modulating the Renin-Angiotensin System (RAS) and Oxidative Stress Pathways. J AM Coll Surg. 2011; 3(213):S18, 2011.
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Sheldon HK, Gainsbury ML, Cassidy MR, Chu DI, Stucchi AF, Becker JM. A sprayable hyaluronate/carboxymethylcellulose adhesion barrier exhibits regional adhesion reduction efficacy and does not impair intestinal healing. J Gastrointest Surg. 2012 Feb; 16(2):325-33.View Related Profiles. PMID: 21983948; DOI: 10.1007/s11605-011-1709-1;
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Chu, DI., Gainsbury ML., Howard, LA., Stucchi, AF., Becker, JM. . Early vs. Late Adhesiolysis for Adhesive-Related Intestinal Obstruction: A Nationwide Analysis of Inpatient Outcomes. J AM Coll Surg. 2011; 3(213):S44-S45, 2011.
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Kosaka, H., Gainsbury, ML., Cassidy, MR., Sheldon, HK., Stucchi, AF., Becker, JM. . A Neurokinin-1 Receptor (NK1R) antagonist (NK-1RA) that reduces postoperative adhesions reduces the adhesion related chemokines CXCL1(KC) and CXCL2 (MIP-2) and their receptor, CXCR2. J AM Coll Surg. 2011; 3(213):S18-S19, 2011..
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Gillespie E, Leeman SE, Watts LA, Coukos JA, O'Brien MJ, Cerda SR, Farraye FA, Stucchi AF, Becker JM. Truncated neurokinin-1 receptor is increased in colonic epithelial cells from patients with colitis-associated cancer. Proc Natl Acad Sci U S A. 2011 Oct 18; 108(42):17420-5.View Related Profiles. PMID: 21969570; PMCID: PMC3198340; DOI: 10.1073/pnas.1114275108;
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Becker, J.M. and Stucchi, A.F. . . The Management of Acute and Chronic Pouchitis. Lichtenstein’s Medical Management of Ulcerative Colitis,. 2011.
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Chu DI, Lim R, Heydrick S, Gainsbury ML, Abdou R, D'Addese L, Reed KL, Stucchi AF, Becker JM. N-acetyl-l-cysteine decreases intra-abdominal adhesion formation through the upregulation of peritoneal fibrinolytic activity and antioxidant defenses. Surgery. 2011 Jun; 149(6):801-12.View Related Profiles. PMID: 21621684; DOI: 10.1016/j.surg.2011.02.015;
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Gainsbury ML, Chu DI, Howard LA, Coukos JA, Farraye FA, Stucchi AF, Becker JM. Preoperative infliximab is not associated with an increased risk of short-term postoperative complications after restorative proctocolectomy and ileal pouch-anal anastomosis. J Gastrointest Surg. 2011 Mar; 15(3):397-403.View Related Profiles. PMID: 21246415; DOI: 10.1007/s11605-010-1385-6;
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Farraye FA, Nimitphong H, Stucchi A, Dendrinos K, Boulanger AB, Vijjeswarapu A, Tanennbaum A, Biancuzzo R, Chen TC, Holick MF. Use of a novel vitamin D bioavailability test demonstrates that vitamin D absorption is decreased in patients with quiescent Crohn's disease. Inflamm Bowel Dis. 2011 Oct; 17(10):2116-21.View Related Profiles. PMID: 21910173; DOI: 10.1002/ibd.21595;
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Chu DI, Stucchi AF, Becker JM. A "solution" to the application of an effective physical barrier for the prevention of intra-abdominal adhesions. J Surg Res. 2011 May 1; 167(1):33-6. PMID: 20828754; DOI: 10.1016/j.jss.2010.06.005;
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Lim R, Stucchi AF, Morrill JM, Reed KL, Lynch R, Becker JM. The efficacy of a hyaluronate-carboxymethylcellulose bioresorbable membrane that reduces postoperative adhesions is increased by the intra-operative co-administration of a neurokinin 1 receptor antagonist in a rat model. Surgery. 2010 Nov; 148(5):991-9.View Related Profiles. PMID: 20338610; DOI: 10.1016/j.surg.2010.01.024;
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Prushik SG, Stucchi AF, Matteotti R, Aarons CB, Reed KL, Gower AC, Becker JM. Open adhesiolysis is more effective in reducing adhesion reformation than laparoscopic adhesiolysis in an experimental model. Br J Surg. 2010 Mar; 97(3):420-7.View Related Profiles. PMID: 20101595; DOI: 10.1002/bjs.6899;
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Litzendorf ME, Stucchi AF, Wishnia S, Lightner A, Becker JM. Completion mucosectomy for retained rectal mucosa following restorative proctocolectomy with double-stapled ileal pouch-anal anastomosis. J Gastrointest Surg. 2010 Mar; 14(3):562-9.View Related Profiles. PMID: 19937191; DOI: 10.1007/s11605-009-1099-9;
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Noronha AM, Liang Y, Hetzel JT, Hasturk H, Kantarci A, Stucchi A, Zhang Y, Nikolajczyk BS, Farraye FA, Ganley-Leal LM. Hyperactivated B cells in human inflammatory bowel disease. J Leukoc Biol. 2009 Oct; 86(4):1007-16.View Related Profiles. PMID: 19589946; PMCID: PMC2796625; DOI: 10.1189/jlb.0309203;
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Stucchi AF, Shebani KO, Reed KL, Gower AC, Alapatt MF, Crivello KM, McClung JP, Becker JM. Stasis predisposes ileal pouch inflammation in a rat model of ileal pouch-anal anastomosis. J Surg Res. 2010 Nov; 164(1):75-83.View Related Profiles. PMID: 19691981; DOI: 10.1016/j.jss.2009.03.049;
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Norata GD, Baragetti I, Raselli S, Stucchi A, Garlaschelli K, Vettoretti S, Piloni G, Buccianti G, Catapano AL. Plasma adiponectin levels in chronic kidney disease patients: relation with molecular inflammatory profile and metabolic status. Nutr Metab Cardiovasc Dis. 2010 Jan; 20(1):56-63. PMID: 19359150; DOI: 10.1016/j.numecd.2009.01.011;
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Becker JM, Stucchi AF. Treatment of choice for acute severe steroid-refractory ulcerative colitis is colectomy. Inflamm Bowel Dis. 2009 Jan; 15(1):146-9. PMID: 19009603; DOI: 10.1002/ibd.20780;
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Lim R, Morrill JM, Lynch RC, Reed KL, Gower AC, Leeman SE, Stucchi AF, Becker JM. Practical limitations of bioresorbable membranes in the prevention of intra-abdominal adhesions. J Gastrointest Surg. 2009 Jan; 13(1):35-41; discussion 41-2.View Related Profiles. PMID: 18854958; DOI: 10.1007/s11605-008-0724-3;
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Lim R, Morrill JM, Prushik SG, Reed KL, Gower AC, Leeman SE, Stucchi AF, Becker JM. An FDA approved neurokinin-1 receptor antagonist is effective in reducing intraabdominal adhesions when administered intraperitoneally, but not orally. J Gastrointest Surg. 2008 Oct; 12(10):1754-61.View Related Profiles. PMID: 18709513; DOI: 10.1007/s11605-008-0634-4;
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Reed KL, Stucchi AF, Becker JM. Pharmacologic inhibition of adhesion formation and peritoneal tissue-type plasminogen activator activity. Semin Reprod Med. 2008 Jul; 26(4):331-40. PMID: 18756410; DOI: 10.1055/s-0028-1082391;
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Reed KL, Stucchi AF, Becker JM. The peritoneal fibrinolytic response to conventional and prolonged surgery is similar. J Surg Res. 2009 Apr; 152(2):175-7. PMID: 19062043; DOI: 10.1016/j.jss.2008.04.042;
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Tzianabos AO, Holsti MA, Zheng XX, Stucchi AF, Kuchroo VK, Strom TB, Glimcher LH, Cruikshank WW. Functional Th1 cells are required for surgical adhesion formation in a murine model. J Immunol. 2008 May 15; 180(10):6970-6.View Related Profiles. PMID: 18453619
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Cohen PA, Gower AC, Stucchi AF, Leeman SE, Becker JM, Reed KL. A neurokinin-1 receptor antagonist that reduces intraabdominal adhesion formation increases peritoneal matrix metalloproteinase activity. Wound Repair Regen. 2007 Nov-Dec; 15(6):800-8.View Related Profiles. PMID: 18028127
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Heydrick SJ, Reed KL, Cohen PA, Aarons CB, Gower AC, Becker JM, Stucchi AF. Intraperitoneal administration of methylene blue attenuates oxidative stress, increases peritoneal fibrinolysis, and inhibits intraabdominal adhesion formation. J Surg Res. 2007 Dec; 143(2):311-9.View Related Profiles. PMID: 17826794
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Reed KL, Heydrick SJ, Aarons CB, Prushik S, Gower AC, Stucchi AF, Becker JM. A neurokinin-1 receptor antagonist that reduces intra-abdominal adhesion formation decreases oxidative stress in the peritoneum. Am J Physiol Gastrointest Liver Physiol. 2007 Sep; 293(3):G544-51.View Related Profiles. PMID: 17627972
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Aarons CB, Bajenova O, Andrews C, Heydrick S, Bushell KN, Reed KL, Thomas P, Becker JM, Stucchi AF. Carcinoembryonic antigen-stimulated THP-1 macrophages activate endothelial cells and increase cell-cell adhesion of colorectal cancer cells. Clin Exp Metastasis. 2007; 24(3):201-9.View Related Profiles. PMID: 17487559
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Prushik SG, Aarons CB, Matteotti R, Reed KL, Gower AC, Leeman SE, Stucchi AF, Becker JM. A neurokinin 1 receptor antagonist decreases adhesion reformation after laparoscopic lysis of adhesions in a rat model of adhesion formation. Surg Endosc. 2007 Oct; 21(10):1790-5.View Related Profiles. PMID: 17356938
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Cohen PA, Aarons CB, Gower AC, Stucchi AF, Leeman SE, Becker JM, Reed KL. The effectiveness of a single intraperitoneal infusion of a neurokinin-1 receptor antagonist in reducing postoperative adhesion formation is time dependent. Surgery. 2007 Mar; 141(3):368-75.View Related Profiles. PMID: 17349849
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Stucchi AF, Aarons CB, Becker JM. Surgical approaches to cancer in patients who have inflammatory bowel disease. Gastroenterol Clin North Am. 2006 Sep; 35(3):641-73. PMID: 16952745
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Dendrinos KG, Becker JM, Stucchi AF, Saubermann LJ, LaMorte W, Farraye FA. Anti-Saccharomyces cerevisiae antibodies are associated with the development of postoperative fistulas following ileal pouch-anal anastomosis. J Gastrointest Surg. 2006 Jul-Aug; 10(7):1060-4.View Related Profiles. PMID: 16843878
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Stucchi A, Reed K, O'Brien M, Cerda S, Andrews C, Gower A, Bushell K, Amar S, Leeman S, Becker J. A new transcription factor that regulates TNF-alpha gene expression, LITAF, is increased in intestinal tissues from patients with CD and UC. Inflamm Bowel Dis. 2006 Jul; 12(7):581-7.View Related Profiles. PMID: 16804395
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Becker JM, Prushik SG, Stucchi AF. Infliximab for ulcerative colitis. N Engl J Med. 2006 Mar 30; 354(13):1424-6; author reply 1424-6. PMID: 16575950
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Yantiss RK, Farraye FA, O'Brien MJ, Fruin AB, Stucchi AF, Becker JM, Reddy SI, Odze RD. Prognostic significance of superficial fissuring ulceration in patients with severe "indeterminate" colitis. Am J Surg Pathol. 2006 Feb; 30(2):165-70.View Related Profiles. PMID: 16434889
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Reed KL, Fruin AB, Gower AC, Gonzales KD, Stucchi AF, Andry CD, O'Brien M, Becker JM. NF-kappaB activation precedes increases in mRNA encoding neurokinin-1 receptor, proinflammatory cytokines, and adhesion molecules in dextran sulfate sodium-induced colitis in rats. Dig Dis Sci. 2005 Dec; 50(12):2366-78.View Related Profiles. PMID: 16416193
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Haskell H, Andrews CW, Reddy SI, Dendrinos K, Farraye FA, Stucchi AF, Becker JM, Odze RD. Pathologic features and clinical significance of "backwash" ileitis in ulcerative colitis. Am J Surg Pathol. 2005 Nov; 29(11):1472-81.View Related Profiles. PMID: 16224214
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Becker JM, Stucchi AF. Intra-abdominal adhesion prevention: are we getting any closer? Ann Surg. 2004 Aug; 240(2):202-4. PMID: 15273541; PMCID: PMC1356394
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Yantiss RK, Sapp HL, Farraye FA, El-Zammar O, O'Brien MJ, Fruin AB, Stucchi AF, Brien TP, Becker JM, Odze RD. Histologic predictors of pouchitis in patients with chronic ulcerative colitis. Am J Surg Pathol. 2004 Aug; 28(8):999-1006.View Related Profiles. PMID: 15252305
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Reed KL, Fruin AB, Gower AC, Stucchi AF, Leeman SE, Becker JM. A neurokinin 1 receptor antagonist decreases postoperative peritoneal adhesion formation and increases peritoneal fibrinolytic activity. Proc Natl Acad Sci U S A. 2004 Jun 15; 101(24):9115-20.View Related Profiles. PMID: 15187234; PMCID: PMC428482
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Becker JM, Stucchi AF. Proctocolectomy with ileoanal anastomosis. J Gastrointest Surg. 2004 May-Jun; 8(4):376-86. PMID: 15120354
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Stucchi AF, Shebani KO, Leeman SE, Wang CC, Reed KL, Fruin AB, Gower AC, McClung JP, Andry CD, O'Brien MJ, Pothoulakis C, Becker JM. A neurokinin 1 receptor antagonist reduces an ongoing ileal pouch inflammation and the response to a subsequent inflammatory stimulus. Am J Physiol Gastrointest Liver Physiol. 2003 Dec; 285(6):G1259-67.View Related Profiles. PMID: 12893626
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Fruin AB, El-Zammer O, Stucchi AF, O'Brien M, Becker JM. Colonic metaplasia in the ileal pouch is associated with inflammation and is not the result of long-term adaptation. J Gastrointest Surg. 2003 Feb; 7(2):246-53; discussion 253-4.View Related Profiles. PMID: 12600449
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Reed KL, Fruin AB, Bishop-Bartolomei KK, Gower AC, Nicolaou M, Stucchi AF, Leeman SE, Becker JM. Neurokinin-1 receptor and substance P messenger RNA levels increase during intraabdominal adhesion formation. J Surg Res. 2002 Nov; 108(1):165-72.View Related Profiles. PMID: 12443729
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Shebani KO, Stucchi AF, Fruin B, McClung JP, Gee D, Beer ER, LaMorte WW, Becker JM. Pouchitis in a rat model of ileal J pouch-anal anastomosis. Inflamm Bowel Dis. 2002 Jan; 8(1):23-34.View Related Profiles. PMID: 11837935
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Klings ES, Christman BW, McClung J, Stucchi AF, McMahon L, Brauer M, Farber HW. Increased F2 isoprostanes in the acute chest syndrome of sickle cell disease as a marker of oxidative stress. Am J Respir Crit Care Med. 2001 Oct 1; 164(7):1248-52.View Related Profiles. PMID: 11673218
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Stucchi AF, Shofer S, Leeman S, Materne O, Beer E, McClung J, Shebani K, Moore F, O'Brien M, Becker JM. NK-1 antagonist reduces colonic inflammation and oxidative stress in dextran sulfate-induced colitis in rats. Am J Physiol Gastrointest Liver Physiol. 2000 Dec; 279(6):G1298-306.View Related Profiles. PMID: 11093954
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Shebani KO, Stucchi AF, McClung JP, Beer ER, LaMorte WW, Becker JM. Role of stasis and oxidative stress in ileal pouch inflammation. J Surg Res. 2000 May 1; 90(1):67-75.View Related Profiles. PMID: 10781377
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Ghellai AM, Stucchi AF, Chegini N, Ma C, Andry CD, Kaseta JM, Burns JW, Skinner KC, Becker JM. Role of transforming growth factor beta-1 in peritonitis-induced adhesions. J Gastrointest Surg. 2000 May-Jun; 4(3):316-23.View Related Profiles. PMID: 10769096
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Ghellai AM, Stucchi AF, Lynch DJ, Skinner KC, Colt MJ, Becker JM. Role of a hyaluronate-based membrane in the prevention of peritonitis-induced adhesions. J Gastrointest Surg. 2000 May-Jun; 4(3):310-5. PMID: 10769095
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Saltzberg SS, DiEdwardo C, Scott TE, LaMorte WW, Stucchi AF, Becker JM. Ileal pouch salvage following failed ileal pouch- anal anastomosis. J Gastrointest Surg. 1999 Nov-Dec; 3(6):633-41.View Related Profiles. PMID: 10554371
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Becker JM, Stucchi AF, Bryant DE. How do you treat refractory pouchitis and when do you decide to remove the pouch? Inflamm Bowel Dis. 1998 May; 4(2):167-9; discussion 170-1. PMID: 9589303