Ji-Xin Cheng, PhD
Boston University College of Engineering
Electrical and Computer Engineering

PhD, University of Science and Technology of China (Teiching)
BS, University of Science and Technology of China (Teiching)

Dr. Ji-Xin Cheng attended University of Science and Technology of China (USTC) from 1989 to 1994. From 1994 to 1998, he carried out his PhD study on bond-selective chemistry at USTC. As a graduate student, he worked as a research assistant at Universite Paris-sud (France) on vibrational spectroscopy and the Hong Kong University of Science and Technology (HKUST) on quantum dynamics theory. After postdoctoral training on ultrafast spectroscopy at HKUST, he joined Sunney Xie’s group at Harvard University as a postdoc, where he spearheaded the development of CARS microscopy that allows high-speed vibrational imaging of cells and tissues. Cheng joined Purdue University in 2003 as Assistant Professor in Weldon School of Biomedical Engineering and Department of Chemistry, promoted to Associate Professor in 2009 and Full Professor in 2013. He joined Boston University as the Inaugural Theodore Moustakas Chair Professor in Photonics and Optoelectronics in summer 2017. Dr. Cheng and his team have been constantly at the most forefront of chemical imaging in innovation, discovery, and clinical translation. For his contributions to the field of vibrational spectroscopic imaging, Cheng received the 2020 Pittsburgh Spectroscopy Award from the Spectroscopy Society of Pittsburgh, the 2019 Ellis R. Lippincott Award from OSA, Society for Applied Spectroscopy, Coblentz Society, and the 2015 Craver Award from Coblentz Society. Cheng is authored in over 280 peer-reviewed articles with an h-index of 83 (Google Scholar). His research has been supported by over 30 million ($) fund from federal agencies including NIH, NSF, DoD, DoE and private foundations including the Keck Foundation. In 2014 He co-founded Vibronix Inc which has the mission of saving lives through medical device innovations. Cheng is a Fellow of Optical Society of America, a Fellow of American Institute of Medicine and Biological Engineering, and associate editor of Science Advances.

Boston University College of Engineering
Biomedical Engineering

Boston University College of Arts and Sciences

Boston University College of Arts and Sciences

Incorporation of quantitative SRS imaging in sEISA for developing anticancer nanomedicines
03/01/2022 - 02/28/2028 (Subcontract PI)
Brandeis University NIH NCI

Rapid AST through Metabolic Imaging at Single Cell Level
07/07/2023 - 06/30/2027 (PI)
NIH/National Institute of Allergy & Infectious Diseases

High-content High-speed Chemical Imaging of Metabolic Reprogramming by Integration of Advanced Instrumentation and Data Science
04/01/2022 - 12/31/2025 (PI)
NIH/National Institute of Biomedical Imaging & Bioengineering

Bond-selective Intensity Diffraction Tomography
03/01/2023 - 08/31/2025 (Multi-PI)
PI: Ji-Xin Cheng, PhD
Silicon Valley Community Foundation

Sub-millimeter precision wireless neuromodulation using a microwave split ring resonator
08/01/2022 - 07/31/2025 (PI)
NIH/National Eye Institute

Vibrational Spectroscopic Imaging to Unveil Hidden Signatures in Living Systems
07/01/2020 - 06/30/2025 (PI)
NIH/National Institute of General Medical Sciences

Fluorescence Enhanced Photothermal Infrared Spectroscopy (FE-PTIR) – Breakthrough for simultaneous fluorescence microscopy and sub-micron IR spectroscopy
11/01/2022 - 08/31/2024 (Subcontract PI)
Photothermal Spectroscopy Corp. NIH NIGMS

Mapping Cancer Metabolism by Mid-infrared Photothermal Microscopy
09/20/2021 - 08/31/2024 (PI)
NIH/National Cancer Institute

Sensing Vulnerable Plaque in vivo by An All-optical Intravascular Ultrasound and Photoacoustic Catheter
09/01/2020 - 08/31/2024 (PI)
NIH/National Heart, Lung, and Blood Institute

Unveiling the mechanisms of ultrasound neuromodulation via spatially confined stimulation and temporally resolved recording
09/30/2018 - 06/30/2024 (Multi-PI)
PI: Ji-Xin Cheng, PhD
NIH/National Institute of Neurological Disorders & Stroke

Showing 10 of 32 results. Show All Results


Yr Title Project-Sub Proj Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. Kaumeyer BA, Fidai SS, Thakral B, Wang SA, Arber DA, Cheng JX, Gurbuxani S, Venkataraman G. GLUT1 Immunohistochemistry Is a Highly Sensitive and Relatively Specific Marker for Erythroid Lineage in Benign and Malignant Hematopoietic Tissues. Am J Clin Pathol. 2022 Aug 04; 158(2):228-234. PMID: 35311938; DOI: 10.1093/ajcp/aqac034;
  2. Dong PT, Jusuf S, Hui J, Zhan Y, Zhu Y, Liu GY, Cheng JX. Photoinactivation of catalase sensitizes a wide range of bacteria to ROS-producing agents and immune cells. JCI Insight. 2022 May 23; 7(10). PMID: 35446788; PMCID: PMC9220836; DOI: 10.1172/jci.insight.153079;
  3. Liu MD, Li CX, Cheng JX, Zhao TY. Spatial statistical and environmental correlation analyses on vector density, vector infection index and Japanese encephalitis cases at the village and pigsty levels in Liyi County, Shanxi Province, China. Parasit Vectors. 2022 May 19; 15(1):171. PMID: 35590422; PMCID: PMC9118647; DOI: 10.1186/s13071-022-05305-8;
  4. Cheng JX. New "HOPE" laser for photoacoustic imaging of water. Light Sci Appl. 2022 Apr 26; 11(1):107. PMID: 35468889; PMCID: PMC9038744; DOI: 10.1038/s41377-022-00805-9;
  5. Han Y, Hou T, Zhang ZH, Zhu YH, Cheng JX, Zhou H, Wang JX, Feng JT, Liu YF, Guo ZM, Liang XM. Corybungines A-K: Isoquinoline alkaloids from Corydalis bungeana with dopamine D2 receptor activity. Phytochemistry. 2022 Jul; 199:113209. PMID: 35430251; DOI: 10.1016/j.phytochem.2022.113209;
  6. Shi L, Jiang Y, Zheng N, Cheng JX, Yang C. High-precision neural stimulation through optoacoustic emitters. Neurophotonics. 2022 Jul; 9(3):032207. PMID: 35355658; PMCID: PMC8941197; DOI: 10.1117/1.NPh.9.3.032207;
  7. Zhai BT, Tian H, Sun J, Zou JB, Zhang XF, Cheng JX, Shi YJ, Fan Y, Guo DY. Urokinase-type plasminogen activator receptor (uPAR) as a therapeutic target in cancer. J Transl Med. 2022 03 18; 20(1):135. PMID: 35303878; PMCID: PMC8932206; DOI: 10.1186/s12967-022-03329-3;
  8. Han Y, Hou T, Zhang ZH, Wang YD, Cheng JX, Zhou H, Wang JX, Feng JT, Liu YF, Guo ZM, Liang XM. Structurally diverse isoquinoline and amide alkaloids with dopamine D2 receptor antagonism from Corydalis bungeana. Fitoterapia. 2022 Jun; 159:105175. PMID: 35296435; DOI: 10.1016/j.fitote.2022.105175;
  9. Ru-Jian Y, Zhang CY, Hai-Yan H, Pei W, Fu WY, Cheng JX, Xiong YS. Silver-mediated radical oxytrifluoromethylation of unsaturated carboxylic acids for the synthesis of ?-trifluoromethylthio lactones. Org Biomol Chem. 2022 03 09; 20(10):2109-2114. PMID: 35199820; DOI: 10.1039/d2ob00018k;
  10. Zhang M, Seleem MN, Cheng JX. Rapid Antimicrobial Susceptibility Testing by Stimulated Raman Scattering Imaging of Deuterium Incorporation in a Single Bacterium. J Vis Exp. 2022 02 14; (180). PMID: 35225259; PMCID: PMC9682461; DOI: 10.3791/62398;
Showing 10 of 427 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 427 publications over 29 distinct years, with a maximum of 32 publications in 2021


2020 Spectroscopy Society of Pittsburgh: Pittsburgh Spectroscopy Award
2019 Coblentz Society: Ellis R. Lippincott Award from OSA, Society for Applied Spectroscopy
2019 Fellow of Optical Society of America
2017 Boston University: Inaugural Moustakas Chair Professor in Optoelectronics and Photonics
2016 Purdue University College of Engineering Research Excellence Award
2015 Craver Award from Coblentz Society
2014 Fellow of American Institute of Medicine and Biological Engineering (AIMBE)
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