Dr. Menn-Josephy is a board-certified nephrologist with a special interest in Autoimmune Kidney Diseases and Lupus Nephritis. She serves as the Nephrology Director of the Lupus Multidisciplinary Program at Boston Medical Center, which operates as a regional and national referral center for patients who suffer from lupus and lupus nephritis.
Together with her colleagues, Dr. Menn-Josephy developed a unique care model that enables lupus and lupus nephritis patients to receive comprehensive care from rheumatology, nephrology, and dermatology disciplines, improving their health and reducing health-related disparities. Dr. Menn-Josephy conducts groundbreaking clinical trials, including pioneering CAR-T therapy for lupus nephritis, and is committed to providing novel therapies to lupus patients. Over the past years. she has been involved is establishing educational programs in the field of lupus nephritis on institutional, regional, and national levels.
As part of her interest in translational research in the field of lupus nephritis, Dr. Menn-Josephy, along with her colleagues, established an autoimmunity clinical registry and patient biobank with the goal of studying lupus pathogenesis to identify new therapeutic targets.
Dr. Menn-Josephy serves as the Associate Program Director for the Nephrology Fellowship Program, where she established a coaching initiative for fellows to enhance their sense of belonging and well-being within the section. This program provides personalized mentorship and professional development opportunities, creating a supportive environment that helps fellows thrive during their specialized training.
Diversity, Equity, Inclusion and Accessibility
I am dedicated to reducing health disparities among our lupus and lupus nephritis patients in the lupus clinic that are from underrepresented minorities. In lupus disease, Hispanic and African American or African- Caribbean patients have increased risk for developing lupus nephritis, as well as End Stage Kidney Disease, and other lupus related complications. Our lupus program is strongly committed to address and support mental and socio-economic challenges that our patients face, and to advocate for resources to support them. In 2020, we received the Quality Improvement in Lupus Care for the Underserved award from the Department of Medicine for our work in improving compliance with appointments in our lupus clinic.
As the Associate Program Director in the Nephrology Program, I am dedicated to recruiting and creating a working and learning community that promotes and welcomes trainees from a variety of backgrounds and creates access to opportunities for a diverse collection of applicants. I am committed to mentoring and sponsoring our trainees from underrepresented minorities, and to promoting equity, diversity and inclusion in our training program.
Member
Boston University
Amyloidosis Center
This tab shows grant data from BMC Sponsored Research. It includes:
- Grant title
- Project period and this person’s role on the grant
- PI name, if this person is not the PI (the name will link if PI has a BU Profile)
- Funding source(s). An arrow indicates the flow of funding if multiple sponsors.
- Some grants will show an agency award/project number, and may be a link.
- Data is sorted by project end date, and updated monthly.
This tab shows grant data from BU Sponsored Research. It includes:
- Grant title
- Project period and this person’s role on the grant
- PI name, if this person is not the PI (the name will link if PI has a BU Profile)
- Funding source(s). An arrow indicates the flow of funding if multiple sponsors.
- Some grants will show an agency award/project number, and may be a link.
- Data is sorted by project end date, and updated monthly.
This tab shows grant data that did not automatically get imported into Profiles
from BU or BMC sources.
- Grant title
- Project period and this person’s role on the grant
- PI name, if this person is not the PI (the name will link if PI has a BU Profile)
- Funding source(s). An arrow indicates the flow of funding if multiple sponsors.
- Some grants will show an agency award/project number, and may be a link.
- Data is sorted by project end date, and updated monthly.
This tab shows grant data from the Boston VA. We are only showing grant title, and only for people in the role of PI.
CYTB323J12201: A Phase 2, adaptive, randomized, open-label, assessor blinded
active-controlled study to evaluate the efficacy and safety of rapcabtagene autoleucel versus Standard of Care in patients suffering from systemic lupus erythematosus (SLE) with09/24/2024 - 09/23/2027 (PI)
Novartis Pharma Corp
A Phase 2, Randomized, Double-blind, Placebo-controlled Evaluation of the Safety and Efficacy01/21/2020 - 01/20/2023 (PI)
Bristol-Myers Squibb Company
Toll-like receptor Induced pathways in lupus nephritis07/01/2016 - 12/31/2017 (PI)
National Kidney Fdtn
|
Yr
|
Title
|
Project-Sub Proj
|
Pubs
|
Publications listed below are automatically derived from MEDLINE/PubMed and other
sources, which might result in incorrect or missing publications. Faculty can
login
to make corrections and additions.
-
Siskind SM, Yadav S, Solomon M, Knapp PE, Menn-Josephy H, Francis J, Rennke HG, Ayalon R, Modzelewski KL. Nephrotic Syndrome as a Complication of Systemic Calcitonin Amyloidosis From Long-Standing Metastatic Medullary Thyroid Cancer. AACE Clin Case Rep. 2024; 10(6):244-248.View Related Profiles. PMID: 39734505; PMCID: PMC11680751; DOI: 10.1016/j.aace.2024.08.007;
-
Menn-Josephy H, Hodge LS, Birardi V, Leher H. Efficacy of Voclosporin in Proliferative Lupus Nephritis with High Levels of Proteinuria. Clin J Am Soc Nephrol. 2024 Mar 01; 19(3):309-318. PMID: 38110196; PMCID: PMC10937024; DOI: 10.2215/CJN.0000000000000297;
-
Schmidt IM, Shohet M, Serrano M, Yadati P, Menn-Josephy H, Ilori T, Eneanya ND, Cleveland Manchanda EC, Waikar SS. Patients' Perspectives on Race and the Use of Race-Based Algorithms in Clinical Decision-Making: a Qualitative Study. J Gen Intern Med. 2023 Jul; 38(9):2045-2051.View Related Profiles. PMID: 36811702; PMCID: PMC9945816; DOI: 10.1007/s11606-023-08035-4;
-
Nader R, Zhen A, Angel-Korman A, Pavlovich SS, Pogrebinsky A, Doros G, Menn-Josephy H, Stern L, Sanchorawala V, Havasi A. Predictors and outcomes of acute kidney injury during autologous stem cell transplantation in AL amyloidosis. Nephrol Dial Transplant. 2022 Jun 23; 37(7):1281-1288.View Related Profiles. PMID: 34043009
-
Li H, Tsokos MG, Bhargava R, Adamopoulos IE, Menn-Josephy H, Stillman IE, Rosenstiel P, Jordan J, Tsokos GC. IL-23 reshapes kidney resident cell metabolism and promotes local kidney inflammation. J Clin Invest. 2021 06 15; 131(12). PMID: 33956666; PMCID: PMC8203450; DOI: 10.1172/JCI142428;
-
-
Bonegio RG, Lin JD, Beaudette-Zlatanova B, York MR, Menn-Josephy H, Yasuda K. Lupus-Associated Immune Complexes Activate Human Neutrophils in an Fc?RIIA-Dependent but TLR-Independent Response. J Immunol. 2019 02 01; 202(3):675-683.View Related Profiles. PMID: 30610165; PMCID: PMC6344272; DOI: 10.4049/jimmunol.1800300;
-
Menn-Josephy H, Lee CS, Nolin A, Christov M, Rybin DV, Weinberg JM, Henderson J, Bonegio R, Havasi A. Renal Interstitial Fibrosis: An Imperfect Predictor of Kidney Disease Progression in Some Patient Cohorts. Am J Nephrol. 2016; 44(4):289-299.View Related Profiles. PMID: 27626625; PMCID: PMC5069171; DOI: 10.1159/000449511;
-
Duffau P, Menn-Josephy H, Cuda CM, Dominguez S, Aprahamian TR, Watkins AA, Yasuda K, Monach P, Lafyatis R, Rice LM, Kenneth Haines G, Gravallese EM, Baum R, Richez C, Perlman H, Bonegio RG, Rifkin IR. Promotion of Inflammatory Arthritis by Interferon Regulatory Factor 5 in a Mouse Model. Arthritis Rheumatol. 2015 Dec; 67(12):3146-57.View Related Profiles. PMID: 26315890; PMCID: PMC4661118; DOI: 10.1002/art.39321;
-
Watkins AA, Yasuda K, Wilson GE, Aprahamian T, Xie Y, Maganto-Garcia E, Shukla P, Oberlander L, Laskow B, Menn-Josephy H, Wu Y, Duffau P, Fried SK, Lichtman AH, Bonegio RG, Rifkin IR. IRF5 deficiency ameliorates lupus but promotes atherosclerosis and metabolic dysfunction in a mouse model of lupus-associated atherosclerosis. J Immunol. 2015 Feb 15; 194(4):1467-79.View Related Profiles. PMID: 25595782; PMCID: PMC4323680; DOI: 10.4049/jimmunol.1402807;
Showing 10 of 14 results.
Show More
-
Menn-Josephy H, Beck LH. Recurrent glomerular disease in the kidney allograft. Front Biosci (Elite Ed). 2015; 7:135-48.View Related Profiles. PMID: 25553369
-
-
Waisman D, Brod V, Rahat MA, Amit-Cohen BC, Lahat N, Rimar D, Menn-Josephy H, David M, Lavon O, Cavari Y, Bitterman H. Dose-related effects of hyperoxia on the lung inflammatory response in septic rats. Shock. 2012 Jan; 37(1):95-102. PMID: 21921827; DOI: 10.1097/SHK.0b013e3182356fc3;
-
This graph shows the total number of publications by year, by first, middle/unknown,
or last author.
| Year | Publications |
|---|
| 2010 | 1 |
| 2012 | 1 |
| 2014 | 1 |
| 2015 | 3 |
| 2016 | 1 |
| 2019 | 1 |
| 2020 | 1 |
| 2021 | 1 |
| 2022 | 1 |
| 2023 | 2 |
| 2024 | 1 |