Gina Peloso, PhD
Assistant Professor
Boston University School of Public Health
Dept of Biostatistics

PhD, Boston University
MA, Boston University




Gina Peloso, PhD, is an Assistant Professor in the Department of Biostatistics. Her primary research focus is statistical genetics. She has contributed to the identification of common genetic variants through genome-wide association studies (GWAS) with complex cardiovascular traits, particularly with plasma lipid levels. She also investigates the role of rare genetic variation using both exome and whole genome sequencing. Furthermore, she leverages genetic variants to answer clinical questions such as predicting risk for disease and whether specific biomarkers are causal. Gina is an active member in the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium, the Global Lipids Genetic Consortium (GLGC), and TOPMed Program.

Investigator
Framingham Heart Study


Member
Boston University
Genome Science Institute




Whole genome sequences in ethically diverse individuals with functional assays and genome editing to characterize the biology of plasma lipids
05/01/2019 - 04/30/2024 (Subcontract PI)
Massachusetts General Hospital NIH NHLBI
1R01HL142711-01A1

Genetic determinants of triglyceride-rich lipoproteins to disentangle CHD risk
04/15/2018 - 02/29/2020 (PI)
NIH/National Heart, Lung, and Blood Institute
5R03HL141439-02

Discovering lipoprotein lipase pathway variants that protect against CHD
02/20/2016 - 11/30/2019 (PI)
NIH/National Heart, Lung, and Blood Institute
5K01HL125751-04



Title

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Ferraro NM, Strober BJ, Einson J, Abell NS, Aguet F, Barbeira AN, Brandt M, Bucan M, Castel SE, Davis JR, Greenwald E, Hess GT, Hilliard AT, Kember RL, Kotis B, Park Y, Peloso G, Ramdas S, Scott AJ, Smail C, Tsang EK, Zekavat SM, Ziosi M, Aradhana, Ardlie KG, Assimes TL, Bassik MC, Brown CD, Correa A, Hall I, Im HK, Li X, Natarajan P, Lappalainen T, Mohammadi P, Montgomery SB, Battle A. Transcriptomic signatures across human tissues identify functional rare genetic variation. Science. 2020 09 11; 369(6509). PMID: 32913073
     
  2. Nomura A, Emdin CA, Won HH, Peloso GM, Natarajan P, Ardissino D, Danesh J, Schunkert H, Correa A, Bown MJ, Samani NJ, Erdmann J, McPherson R, Watkins H, Saleheen D, Elosua R, Kawashiri MA, Tada H, Gupta N, Shah SH, Rader DJ, Gabriel S, Khera AV, Kathiresan S. Heterozygous ATP-binding Cassette Transporter G5 Gene Deficiency and Risk of Coronary Artery Disease. Circ Genom Precis Med. 2020 Aug 30. PMID: 32862661
     
  3. Li X, Li Z, Zhou H, Gaynor SM, Liu Y, Chen H, Sun R, Dey R, Arnett DK, Aslibekyan S, Ballantyne CM, Bielak LF, Blangero J, Boerwinkle E, Bowden DW, Broome JG, Conomos MP, Correa A, Cupples LA, Curran JE, Freedman BI, Guo X, Hindy G, Irvin MR, Kardia SLR, Kathiresan S, Khan AT, Kooperberg CL, Laurie CC, Liu XS, Mahaney MC, Manichaikul AW, Martin LW, Mathias RA, McGarvey ST, Mitchell BD, Montasser ME, Moore JE, Morrison AC, O'Connell JR, Palmer ND, Pampana A, Peralta JM, Peyser PA, Psaty BM, Redline S, Rice KM, Rich SS, Smith JA, Tiwari HK, Tsai MY, Vasan RS, Wang FF, Weeks DE, Weng Z, Wilson JG, Yanek LR, Neale BM, Sunyaev SR, Abecasis GR, Rotter JI, Willer CJ, Peloso GM, Natarajan P, Lin X. Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale. Nat Genet. 2020 Sep; 52(9):969-983.View Related Profiles. PMID: 32839606
     
  4. Honigberg MC, Chaffin M, Aragam K, Bhatt DL, Wood MJ, Sarma AA, Scott NS, Peloso GM, Natarajan P. Genetic Variation in Cardiometabolic Traits and Medication Targets and the Risk of Hypertensive Disorders of Pregnancy. Circulation. 2020 Aug 18; 142(7):711-713. PMID: 32804569
     
  5. Peloso GM, Beiser AS, Satizabal CL, Xanthakis V, Vasan RS, Pase MP, Destefano AL, Seshadri S. Cardiovascular health, genetic risk, and risk of dementia in the Framingham Heart Study. Neurology. 2020 Sep 08; 95(10):e1341-e1350.View Related Profiles. PMID: 32690788
     
  6. Chen Y, Peloso GM, Liu CT, DeStefano AL, Dupuis J. Evaluation of population stratification adjustment using genome-wide or exonic variants. Genet Epidemiol. 2020 Jun 30.View Related Profiles. PMID: 32608112
     
  7. Xu YX, Peloso GM, Nagai TH, Mizoguchi T, Deik A, Bullock K, Lin H, Musunuru K, Yang Q, Vasan RS, Gerszten RE, Clish CB, Rader D, Kathiresan S. EDEM3 Modulates Plasma Triglyceride Level through Its Regulation of LRP1 Expression. iScience. 2020 Apr 24; 23(4):100973.View Related Profiles. PMID: 32213464; DOI: 10.1016/j.isci.2020.100973;
     
  8. Haslam DE, Peloso GM, Herman MA, Dupuis J, Lichtenstein AH, Smith CE, McKeown NM. Beverage Consumption and Longitudinal Changes in Lipoprotein Concentrations and Incident Dyslipidemia in US Adults: The Framingham Heart Study. J Am Heart Assoc. 2020 Mar 03; 9(5):e014083.View Related Profiles. PMID: 32098600
     
  9. Granot-Hershkovitz E, Wu P, Karasik D, Peter I, Peloso GM, Levy D, Vasan RS, Adrienne Cupples L, Liu CT, Meigs JB, Siscovick DS, Dupuis J, Friedlander Y, Hochner H. Searching for parent-of-origin effects on cardiometabolic traits in imprinted genomic regions. Eur J Hum Genet. 2020 May; 28(5):646-655.View Related Profiles. PMID: 31896779
     
  10. Honigberg MC, Zekavat SM, Aragam K, Klarin D, Bhatt DL, Scott NS, Peloso GM, Natarajan P. Long-Term Cardiovascular Risk in Women With Hypertension During Pregnancy. J Am Coll Cardiol. 2019 12 03; 74(22):2743-2754. PMID: 31727424
     
Showing 10 of 102 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 102 publications over 14 distinct years, with a maximum of 19 publications in 2016

YearPublications
20071
20081
20095
20105
20113
20127
201310
20148
20157
201619
201710
201813
20194
20209

In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Risk Factors
Biostatistics
Human Genetics
Statistical Genetics
Statistical Data Analyses
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801 Massachusetts Ave Crosstown Center
Boston MA 02118
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