Robert Davey, PhD
Professor
Boston University Chobanian & Avedisian School of Medicine
Dept of Microbiology

PhD, University of Adelaide
BSc, University of Adelaide



Dr. Robert Davey, PhD is a currently a Professor of Microbiology at the Chobanian and Avedisian School of Medicine. Dr. Davey received his doctorate in Microbiology and Immunology at the University of Adelaide in Australia. He continued his training as a Postdoctoral Fellow at the Howard Hughes Medical Institute and then at the Division of Hematology, both with Dr. James Cunningham at Brigham and Women's Hospital and Harvard Medical School.

Dr. Davey's first academic appointment was as an Instructor in Medicine at Harvard. He then held an Assistant Professor position which he got promoted to Adjunct Associate Professor at the Department of Microbiology and Immunology at the University of Texas Medical Branch.

Dr. Davey was also a Ewing Halsell Scholar and Scientist at the Department of Virology and Immunology at the Texas Biomedical Research Institute. As a Scientist at the Texas Biomedical Research Institute, Dr. Davey's work was focused on identification of cellular factors important for establishing infection by filovirus and bunyaviruses. His work has culminated in a deeper understanding of the entry and cell signaling pathways that are used by these viruses to penetrate the cell membrane and establish infection. His work with Ebolavirus has been published in the high-impact journals PLoS Pathogens, PNAS and a new article on host factor dependence in Science that was featured on the cover page. Dr. Davey’s group works collaboratively with a number of groups providing sophisticated molecular biology and cell biology techniques for the study of pathogenic viruses including Ebolavirus for which the lab mainly works. He has developed high throughput screening techniques for Ebolavirus. He also performs contract work testing drugs and compounds for ebolavirus infection inhibition. His team is well trained in ABSL4 procedures and have been working with Ebolavirus since 2006.

From 2015-2017, Dr. Davey held the role of Interim Chair in the Department of Virology and Immunology at the Texas Biomedical Research Institute. He is also Director of ABSL4 at the Texas Biomedical Research Institute.

Faculty
Boston University
National Emerging Infectious Disease Lab


Member
Boston University Chobanian & Avedisian School of Medicine
Evans Center for Interdisciplinary Biomedical Research


Graduate Faculty (Primary Mentor of Grad Students)
Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences




National Emerging Infectious Diseases Laboratories Operations
07/08/2021 - 06/30/2026 (Key Person)
PI: Ronald B. Corley, PhD
NIH/National Institute of Allergy & Infectious Diseases
2UC7AI095321-08

Midwest AViDD Center - CORE E
05/16/2022 - 04/30/2025 (Subcontract PI)
Regents of the University of Minnesota NIH NIAID
1U19AI171954-01

Center for Antiviral Medicines & Pandemic Preparedness (CAMPP) - PROJECT 6
05/16/2022 - 04/30/2025 (Subcontract PI)
The Scripps Research Institute NIH NIAID
1U19AI171443-01

Perturbing virus replication with interfering peptides
04/25/2022 - 03/31/2024 (Subcontract PI)
Purdue University NIH NIAID
1R21AI166736-01

Assay development and execution of live virus testing in support of the Harvard-AbbVie Research Collaboration
03/01/2021 - 02/28/2024 (Subcontract PI)
President & Fellows of Harvard College on behalf of Harvard Medical School AbbVie


Evaluation of SARS-COV-2 nuclease conjugates for treatment in the rodent model of SARS-COV-2 disease
07/01/2021 - 12/31/2023 (PI)
Massachusetts Institute of Technology


STTR Phase I: Aminomethyl benzamides as novel anti Ebola agents
08/16/2019 - 07/31/2023 (Subcontract PI)
Chicago BioSolutions, Inc. NIH NIAID
5R42AI126971-04

Antiviral Lead Identification to Treat Filovirus Infections
08/12/2019 - 07/31/2023 (Subcontract PI)
Purdue University NIH NIAID
5R01AI128364-04

Modeling Filovirus Infection of and Trafficking through Skin
08/01/2018 - 07/31/2023 (Subcontract PI)
The University of Iowa NIH NIAID
5 R01 AI134733-04

Investigation of the role of phosphatidic acid metabolism in filovirus budding
03/01/2021 - 02/28/2023 (Subcontract PI)
Purdue University NIH NIAID
5R21AI142651-02

Showing 10 of 19 results. Show All Results


Title


Yr Title Project-Sub Proj Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Mishra N, Teyra J, Boytz R, Miersch S, Merritt TN, Cardarelli L, Gorelik M, Mihalic F, Jemth P, Davey RA, Sidhu SS, Leung DW, Amarasinghe GK. Monoclonal antibodies binding data for SARS-CoV-2 proteins. Data Brief. 2022 Aug; 43:108415. PMID: 35789908; PMCID: PMC9232259; DOI: 10.1016/j.dib.2022.108415;
     
  2. Gourronc FA, Rebagliati MR, Kramer-Riesberg B, Fleck AM, Patten JJ, Geohegan-Barek K, Messingham KN, Davey RA, Maury W, Klingelhutz AJ. Adipocytes are susceptible to Ebola Virus infection. Virology. 2022 Aug; 573:12-22. PMID: 35690007; PMCID: PMC9413353; DOI: 10.1016/j.virol.2022.05.007;
     
  3. Mishra N, Teyra J, Boytz R, Miersch S, Merritt TN, Cardarelli L, Gorelik M, Mihalic F, Jemth P, Davey RA, Sidhu SS, Leung DW, Amarasinghe GK. Development of Monoclonal Antibodies to Detect for SARS-CoV-2 Proteins. J Mol Biol. 2022 May 30; 434(10):167583. PMID: 35405107; PMCID: PMC8993412; DOI: 10.1016/j.jmb.2022.167583;
     
  4. Plescia CB, Lindstrom AR, Quintero MV, Keiser P, Anantpadma M, Davey R, Stahelin RV, Davisson VJ. Evaluation of Phenol-Substituted Diphyllin Derivatives as Selective Antagonists for Ebola Virus Entry. ACS Infect Dis. 2022 May 13; 8(5):942-957. PMID: 35357134; PMCID: PMC9112336; DOI: 10.1021/acsinfecdis.1c00474;
     
  5. El-Sayed NS, Jureka AS, Edwards MR, Lohan S, Williams CG, Keiser PT, Davey RA, Totonchy J, Tiwari RK, Basler CF, Parang K. Synthesis and antiviral activity of fatty acyl conjugates of remdesivir against severe acute respiratory syndrome coronavirus 2 and Ebola virus. Eur J Med Chem. 2021 Dec 15; 226:113862. PMID: 34583312; PMCID: PMC8454092; DOI: 10.1016/j.ejmech.2021.113862;
     
  6. Lennemann NJ, Dillard J, Ruggio N, Cooney AL, Schaack GA, Davey RA, Maury W. A Naturally Occurring Polymorphism in the Base of Sudan Virus Glycoprotein Decreases Glycoprotein Stability in a Species-Dependent Manner. J Virol. 2021 08 25; 95(18):e0107321. PMID: 34232742; PMCID: PMC8387054; DOI: 10.1128/JVI.01073-21;
     
  7. Batra J, Mori H, Small GI, Anantpadma M, Shtanko O, Mishra N, Zhang M, Liu D, Williams CG, Biedenkopf N, Becker S, Gross ML, Leung DW, Davey RA, Amarasinghe GK, Krogan NJ, Basler CF. Non-canonical proline-tyrosine interactions with multiple host proteins regulate Ebola virus infection. EMBO J. 2021 09 15; 40(18):e105658. PMID: 34260076; PMCID: PMC8441301; DOI: 10.15252/embj.2020105658;
     
  8. Morselli Gysi D, do Valle Í, Zitnik M, Ameli A, Gan X, Varol O, Ghiassian SD, Patten JJ, Davey RA, Loscalzo J, Barabási AL. Network medicine framework for identifying drug-repurposing opportunities for COVID-19. Proc Natl Acad Sci U S A. 2021 05 11; 118(19). PMID: 33906951; PMCID: PMC8126852; DOI: 10.1073/pnas.2025581118;
     
  9. Mena EL, Donahue CJ, Vaites LP, Li J, Rona G, O'Leary C, Lignitto L, Miwatani-Minter B, Paulo JA, Dhabaria A, Ueberheide B, Gygi SP, Pagano M, Harper JW, Davey RA, Elledge SJ. ORF10-Cullin-2-ZYG11B complex is not required for SARS-CoV-2 infection. Proc Natl Acad Sci U S A. 2021 04 27; 118(17). PMID: 33827988; PMCID: PMC8092598; DOI: 10.1073/pnas.2023157118;
     
  10. Patten JJ, Keiser PT, Gysi D, Menichetti G, Mori H, Donahue CJ, Gan X, Do Valle I, Geoghegan-Barek K, Anantpadma M, Berrigan JL, Jalloh S, Ayazika T, Wagner F, Zitnik M, Ayehunie S, Anderson D, Loscalzo J, Gummuluru S, Namchuk MN, Barabasi AL, Davey RA. Multidose evaluation of 6,710 drug repurposing library identifies potent SARS-CoV-2 infection inhibitors In Vitro and In Vivo. bioRxiv. 2021 Apr 22.View Related Profiles. PMID: 33907750; PMCID: PMC8077576; DOI: 10.1101/2021.04.20.440626;
     
Showing 10 of 107 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 107 publications over 26 distinct years, with a maximum of 11 publications in 2021

YearPublications
19911
19922
19961
19972
19981
19991
20011
20041
20052
20068
20073
20084
20092
20104
20116
20126
20134
20147
20157
20165
20173
20188
20194
20209
202111
20224


Recent (within 3 months)

Structure and function of the first FDA-approved treatment for Ebola virus discovered

News Medical 1/30/2023

Can COVID-19 Reboot Drug Repurposing?

Inside Precision Medicine 12/20/2022

Best of The Brink 2022: BU’s Most-Read Science and Research Stories

BU Today 12/13/2022

Older

ONE YEAR LATER: LESSONS FROM THE PANDEMIC

BU Today 3/16/2021

In It Together 6/2/2020

WGBH 6/2/2020

BU Scientists Awarded $1.9 Million to Accelerate Coronavirus Research

BU Today 5/13/2020

Massachusetts Consortium Tests Thousands Of Existing Drugs Against Coronavirus

CBS Boston 5/13/2020

Decoding COVID-19

PBS Nova 5/13/2020

BU Labs, Researchers and Students Fight COVID-19

The Daily Free Press 4/29/2020

Episode 195: Does New England Have Enough COVID-19 Tests; The Fight To Save Yiddish

New England News Collaborative 4/23/2020

Will Antibody Testing Help Get People Back to Work?

PBS Newshour 4/21/2020

Needles In A Haystack: Could Existing Drugs Treat COVID-19?

WGBH 4/15/2020

Getting to Know the Enemy

WGBH 4/10/2020

BU NEIDL Scientists Can “See Enemy,” Making Headway on COVID-19 Research

Mirage News 4/7/2020

Coming: A New Appreciation For The Social Benefits Of Graduate Education

Forbes 4/6/2020

Get A Peek Inside The Search For COVID-19 DrugsL

Futurity 3/23/2020

Boston Researchers on the Frontline in the Battle Against Coronavirus

Boston 25 News 3/20/2020

Live Coronavirus Research Gets Underway at BU NEIDL

BU Today 2/19/2020

Ebola Treatment Massively Cuts Death Rate, But It’s No Cure

Futurity 8/16/2019

Malaria Drug Shows Promise For Treating Ebola

Futurity 11/30/2018

Old Drug, New Tricks

BU Today 11/19/2018

2015 San Antonio business journal: Outstanding medical researcher, Healthcare heroes awards
2005 UTMB Graduate school teaching award
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Marburg
Ebolavirus
ABSL4
Virology
Immunology
bunyaviruses
arenaviruses
Junin virus
Lassa Fever
Filoviruses
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Boston MA 02118
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