Robert Davey, PhD
Professor
Boston University School of Medicine
Dept of Microbiology




Dr. Robert Davey, PhD is a currently a Professor of Microbiology at the Boston University School of Medicine. Dr. Davey received his doctorate in Microbiology and Immunology at the University of Adelaide in Australia. He continued his training as a Postdoctoral Fellow at the Howard Hughes Medical Institute and then at the Division of Hematology, both with Dr. James Cunningham at Brigham and Women's Hospital and Harvard Medical School.

Dr. Davey's first academic appointment was as an Instructor in Medicine at Harvard. He then held an Assistant Professor position which he got promoted to Adjunct Associate Professor at the Department of Microbiology and Immunology at the University of Texas Medical Branch.

Dr. Davey was also a Ewing Halsell Scholar and Scientist at the Department of Virology and Immunology at the Texas Biomedical Research Institute. As a Scientist at the Texas Biomedical Research Institute, Dr. Davey's work was focused on identification of cellular factors important for establishing infection by filovirus and bunyaviruses. His work has culminated in a deeper understanding of the entry and cell signaling pathways that are used by these viruses to penetrate the cell membrane and establish infection. His work with Ebolavirus has been published in the high-impact journals PLoS Pathogens, PNAS and a new article on host factor dependence in Science that was featured on the cover page. Dr. Davey’s group works collaboratively with a number of groups providing sophisticated molecular biology and cell biology techniques for the study of pathogenic viruses including Ebolavirus for which the lab mainly works. He has developed high throughput screening techniques for Ebolavirus. He also performs contract work testing drugs and compounds for ebolavirus infection inhibition. His team is well trained in ABSL4 procedures and have been working with Ebolavirus since 2006.

From 2015-2017, Dr. Davey held the role of Interim Chair in the Department of Virology and Immunology at the Texas Biomedical Research Institute. He is also Director of ABSL4 at the Texas Biomedical Research Institute.

2015 San Antonio business journal: Outstanding medical researcher, Healthcare heroes awards
2005 UTMB Graduate school teaching award


Modeling Filovirus Infection of and Trafficking through Skin
08/01/2018 - 07/31/2019 (PI)
The University of Iowa NIH NIAID
1R01AI134733-01A1

Small molecule inhibitors of Ebola virus polymerase function
08/01/2018 - 01/31/2019 (PI)
Georgia State University NIH NIAID
1R01AI125453-01A1




Yr Title Project-Sub Proj Pubs
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Anantpadma M, Lane T, Zorn KM, Lingerfelt MA, Clark AM, Freundlich JS, Davey RA, Madrid PB, Ekins S. Ebola Virus Bayesian Machine Learning Models Enable New in Vitro Leads. ACS Omega. 2019 Jan 31; 4(1):2353-2361. PMID: 30729228.
     
  2. Batra J, Hultquist JF, Liu D, Shtanko O, Von Dollen J, Satkamp L, Jang GM, Luthra P, Schwarz TM, Small GI, Arnett E, Anantpadma M, Reyes A, Leung DW, Kaake R, Haas P, Schmidt CB, Schlesinger LS, LaCount DJ, Davey RA, Amarasinghe GK, Basler CF, Krogan NJ. Protein Interaction Mapping Identifies RBBP6 as a Negative Regulator of Ebola Virus Replication. Cell. 2018 Dec 13; 175(7):1917-1930.e13. PMID: 30550789.
     
  3. Cui Q, Cheng H, Xiong R, Zhang G, Du R, Anantpadma M, Davey RA, Rong L. Identification of Diaryl-Quinoline Compounds as Entry Inhibitors of Ebola Virus. Viruses. 2018 11 30; 10(12). PMID: 30513600.
     
  4. Lindstrom A, Anantpadma M, Baker L, Raghavendra NM, Davey R, Davisson VJ. Phenotypic Prioritization of Diphyllin Derivatives That Block Filoviral Cell Entry by Vacuolar (H+ )-ATPase Inhibition. ChemMedChem. 2018 Dec 20; 13(24):2664-2676. PMID: 30335906.
     
  5. Shtanko O, Reyes AN, Jackson WT, Davey RA. Autophagy-Associated Proteins Control Ebola Virus Internalization Into Host Cells. J Infect Dis. 2018 Nov 22; 218(suppl_5):S346-S354. PMID: 29947774; DOI: 10.1093/infdis/jiy294;.
     
  6. Pascal KE, Dudgeon D, Trefry JC, Anantpadma M, Sakurai Y, Murin CD, Turner HL, Fairhurst J, Torres M, Rafique A, Yan Y, Badithe A, Yu K, Potocky T, Bixler SL, Chance TB, Pratt WD, Rossi FD, Shamblin JD, Wollen SE, Zelko JM, Carrion R, Worwa G, Staples HM, Burakov D, Babb R, Chen G, Martin J, Huang TT, Erlandson K, Willis MS, Armstrong K, Dreier TM, Ward AB, Davey RA, Pitt MLM, Lipsich L, Mason P, Olson W, Stahl N, Kyratsous CA. Development of Clinical-Stage Human Monoclonal Antibodies That Treat Advanced Ebola Virus Disease in Nonhuman Primates. J Infect Dis. 2018 Nov 22; 218(suppl_5):S612-S626. PMID: 29860496; DOI: 10.1093/infdis/jiy285;.
     
  7. Sakurai Y, Sakakibara N, Toyama M, Baba M, Davey RA. Novel amodiaquine derivatives potently inhibit Ebola virus infection. Antiviral Res. 2018 Dec; 160:175-182. PMID: 30395872.
     
  8. Luthra P, Naidoo J, Pietzsch CA, De S, Khadka S, Anantpadma M, Williams CG, Edwards MR, Davey RA, Bukreyev A, Ready JM, Basler CF. Inhibiting pyrimidine biosynthesis impairs Ebola virus replication through depletion of nucleoside pools and activation of innate immune responses. Antiviral Res. 2018 Oct; 158:288-302. PMID: 30144461.
     
  9. Cui Q, Du R, Anantpadma M, Schafer A, Hou L, Tian J, Davey RA, Cheng H, Rong L. Identification of Ellagic Acid from Plant Rhodiola rosea L. as an Anti-Ebola Virus Entry Inhibitor. Viruses. 2018 03 27; 10(4). PMID: 29584652; DOI: 10.3390/v10040152;.
     
  10. Shtanko O, Sakurai Y, Reyes AN, Noël R, Cintrat JC, Gillet D, Barbier J, Davey RA. Retro-2 and its dihydroquinazolinone derivatives inhibit filovirus infection. Antiviral Res. 2018 01; 149:154-163. PMID: 29175127; DOI: 10.1016/j.antiviral.2017.11.016;.
     
Showing 10 of 79 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 79 publications over 23 distinct years, with a maximum of 8 publications in 2006 and 2018

YearPublications
19911
19922
19961
19972
19981
19991
20011
20041
20052
20068
20073
20084
20092
20104
20116
20126
20134
20146
20157
20165
20173
20188
20191
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Marburg
Ebolavirus
ABSL4
Virology
Immunology
bunyaviruses
arenaviruses
Junin virus
Lassa Fever
Filoviruses
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620 Albany Street
Boston MA 02118
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