Richard Sherva, PhD
Assistant Professor
Boston University Chobanian & Avedisian School of Medicine
Biomedical Genetics

PhD, University of Minnesota
MPH, University of Minnesota
BA, Gustavus Adolphus College

My primary interest is in exploring the genetic epidemiology of complex disease using linkage and association methods. I’ve worked on cardiovascular phenotypes including hypertension, metabolic syndrome, and stroke, as well as psychiatric diseases including addiction and ADHD, with a focus on gene x (gene, environment, drug treatment) interactions. My future work will likely involve pharmacogenetics and personalized medicine, with specific focus on Alzheimer’s disease.

Boston University
Evans Center for Interdisciplinary Biomedical Research

Boston University
Genome Science Institute

Graduate Faculty (Primary Mentor of Grad Students)
Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences

Exploring mechanisms driving microbe-induced AD risk using next generation sequence data
09/30/2021 - 05/31/2026 (PI)
NIH/National Institute on Aging

Single Cell Analysis for AMD
09/01/2021 - 09/30/2023 (Subcontract PI)
State University of New York at Buffalo Genentech, Inc

Personnel Agreement for Research Services of Richard Sherva
08/01/2018 - 06/30/2022 (PI)
VA Boston Healthcare System

Genetic Architecture of Memory and Executive Functioning in Alzheimer's Disease
09/01/2014 - 05/31/2019 (Subcontract PI)
University of Washington NIH NIA

Genetics of Rate of Cognitive Decline in a Clinical Trial of AD
11/01/2011 - 10/31/2013 (PI)
Alzheimer's Association


Yr Title Project-Sub Proj Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Hayes JP, Pierce ME, Brown E, Salat D, Logue MW, Constantinescu J, Valerio K, Miller MW, Sherva R, Huber BR, Milberg W, McGlinchey R. Genetic Risk for Alzheimer Disease and Plasma Tau Are Associated With Accelerated Parietal Cortex Thickness Change in Middle-Aged Adults. Neurol Genet. 2023 Feb; 9(1):e200053.View Related Profiles. PMID: 36742995; PMCID: PMC9893442; DOI: 10.1212/NXG.0000000000200053;
  2. Sherva R, Zhang R, Sahelijo N, Jun G, Anglin T, Chanfreau C, Cho K, Fonda JR, Gaziano JM, Harrington KM, Ho YL, Kremen WS, Litkowski E, Lynch J, Neale Z, Roussos P, Marra D, Mez J, Miller MW, Salat DH, Tsuang D, Wolf E, Zeng Q, Panizzon MS, Merritt VC, Farrer LA, Hauger RL, Logue MW. African ancestry GWAS of dementia in a large military cohort identifies significant risk loci. Mol Psychiatry. 2022 Dec 22.View Related Profiles. PMID: 36543923
  3. Logue MW, Miller MW, Sherva R, Zhang R, Harrington KM, Fonda JR, Merritt VC, Panizzon MS, Hauger RL, Wolf EJ, Neale Z, Gaziano JM. Alzheimer's disease and related dementias among aging veterans: Examining gene-by-environment interactions with post-traumatic stress disorder and traumatic brain injury. Alzheimers Dement. 2022 Dec 22.View Related Profiles. PMID: 36546606
  4. Gaddis N, Mathur R, Marks J, Zhou L, Quach B, Waldrop A, Levran O, Agrawal A, Randesi M, Adelson M, Jeffries PW, Martin NG, Degenhardt L, Montgomery GW, Wetherill L, Lai D, Bucholz K, Foroud T, Porjesz B, Runarsdottir V, Tyrfingsson T, Einarsson G, Gudbjartsson DF, Webb BT, Crist RC, Kranzler HR, Sherva R, Zhou H, Hulse G, Wildenauer D, Kelty E, Attia J, Holliday EG, McEvoy M, Scott RJ, Schwab SG, Maher BS, Gruza R, Kreek MJ, Nelson EC, Thorgeirsson T, Stefansson K, Berrettini WH, Gelernter J, Edenberg HJ, Bierut L, Hancock DB, Johnson EO. Multi-trait genome-wide association study of opioid addiction: OPRM1 and beyond. Sci Rep. 2022 Oct 07; 12(1):16873. PMID: 36207451; PMCID: PMC9546890; DOI: 10.1038/s41598-022-21003-y;
  5. Cox J, Sherva R, Wetherill L, Foroud T, Edenberg HJ, Kranzler HR, Gelernter J, Farrer LA. Genome-wide association study of stimulant dependence. Transl Psychiatry. 2021 06 29; 11(1):363.View Related Profiles. PMID: 34226506; PMCID: PMC8257618; DOI: 10.1038/s41398-021-01440-5;
  6. Sherva R, Zhu C, Wetherill L, Edenberg HJ, Johnson E, Degenhardt L, Agrawal A, Martin NG, Nelson E, Kranzler HR, Gelernter J, Farrer LA. Genome-wide association study of phenotypes measuring progression from first cocaine or opioid use to dependence reveals novel risk genes. Explor Med. 2021; 2:60-73.View Related Profiles. PMID: 34124712; PMCID: PMC8192073; DOI: 10.37349/emed.2021.00032;
  7. Quach BC, Bray MJ, Gaddis NC, Liu M, Palviainen T, Minica CC, Zellers S, Sherva R, Aliev F, Nothnagel M, Young KA, Marks JA, Young H, Carnes MU, Guo Y, Waldrop A, Sey NYA, Landi MT, McNeil DW, Drichel D, Farrer LA, Markunas CA, Vink JM, Hottenga JJ, Iacono WG, Kranzler HR, Saccone NL, Neale MC, Madden P, Rietschel M, Marazita ML, McGue M, Won H, Winterer G, Grucza R, Dick DM, Gelernter J, Caporaso NE, Baker TB, Boomsma DI, Kaprio J, Hokanson JE, Vrieze S, Bierut LJ, Johnson EO, Hancock DB. Expanding the genetic architecture of nicotine dependence and its shared genetics with multiple traits. Nat Commun. 2020 11 03; 11(1):5562.View Related Profiles. PMID: 33144568; PMCID: PMC7642344; DOI: 10.1038/s41467-020-19265-z;
  8. Johnson EC, Demontis D, Thorgeirsson TE, Walters RK, Polimanti R, Hatoum AS, Sanchez-Roige S, Paul SE, Wendt FR, Clarke TK, Lai D, Reginsson GW, Zhou H, He J, Baranger DAA, Gudbjartsson DF, Wedow R, Adkins DE, Adkins AE, Alexander J, Bacanu SA, Bigdeli TB, Boden J, Brown SA, Bucholz KK, Bybjerg-Grauholm J, Corley RP, Degenhardt L, Dick DM, Domingue BW, Fox L, Goate AM, Gordon SD, Hack LM, Hancock DB, Hartz SM, Hickie IB, Hougaard DM, Krauter K, Lind PA, McClintick JN, McQueen MB, Meyers JL, Montgomery GW, Mors O, Mortensen PB, Nordentoft M, Pearson JF, Peterson RE, Reynolds MD, Rice JP, Runarsdottir V, Saccone NL, Sherva R, Silberg JL, Tarter RE, Tyrfingsson T, Wall TL, Webb BT, Werge T, Wetherill L, Wright MJ, Zellers S, Adams MJ, Bierut LJ, Boardman JD, Copeland WE, Farrer LA, Foroud TM, Gillespie NA, Grucza RA, Harris KM, Heath AC, Hesselbrock V, Hewitt JK, Hopfer CJ, Horwood J, Iacono WG, Johnson EO, Kendler KS, Kennedy MA, Kranzler HR, Madden PAF, Maes HH, Maher BS, Martin NG, McGue M, McIntosh AM, Medland SE, Nelson EC, Porjesz B, Riley BP, Stallings MC, Vanyukov MM, Vrieze S, Davis LK, Bogdan R, Gelernter J, Edenberg HJ, Stefansson K, Børglum AD, Agrawal A. A large-scale genome-wide association study meta-analysis of cannabis use disorder. Lancet Psychiatry. 2020 12; 7(12):1032-1045.View Related Profiles. PMID: 33096046; PMCID: PMC7674631; DOI: 10.1016/S2215-0366(20)30339-4;
  9. Zhou H, Rentsch CT, Cheng Z, Kember RL, Nunez YZ, Sherva RM, Tate JP, Dao C, Xu K, Polimanti R, Farrer LA, Justice AC, Kranzler HR, Gelernter J. Association of OPRM1 Functional Coding Variant With Opioid Use Disorder: A Genome-Wide Association Study. JAMA Psychiatry. 2020 10 01; 77(10):1072-1080.View Related Profiles. PMID: 32492095; PMCID: PMC7270886; DOI: 10.1001/jamapsychiatry.2020.1206;
  10. Sherva R, Gross A, Mukherjee S, Koesterer R, Amouyel P, Bellenguez C, Dufouil C, Bennett DA, Chibnik L, Cruchaga C, Del-Aguila J, Farrer LA, Mayeux R, Munsie L, Winslow A, Newhouse S, Saykin AJ, Kauwe JSK, Crane PK, Green RC. Genome-wide association study of rate of cognitive decline in Alzheimer's disease patients identifies novel genes and pathways. Alzheimers Dement. 2020 08; 16(8):1134-1145.View Related Profiles. PMID: 32573913; PMCID: PMC7924136; DOI: 10.1002/alz.12106;
Showing 10 of 69 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 69 publications over 17 distinct years, with a maximum of 8 publications in 2017 and 2020


In addition to these self-described keywords below, a list of MeSH based concepts is available here.

genetic epidemiology
Contact for Mentoring:

72 E. Concord St Instructional (L)
Boston MA 02118
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