Richard Sherva | Profiles RNS

Richard Sherva, PhD

Assistant Professor

Boston University Chobanian & Avedisian School of Medicine

Medicine

Biomedical Genetics

PhD, University of Minnesota
MPH, University of Minnesota
BA, Gustavus Adolphus College

Websites

Biomedical Genetics Faculty

ORCID : 0000-0003-2133-1493

My primary interest is in exploring the genetic epidemiology of complex disease using linkage and association methods. I’ve worked on cardiovascular phenotypes including hypertension, metabolic syndrome, and stroke, as well as psychiatric diseases including addiction and ADHD, with a focus on gene x (gene, environment, drug treatment) interactions. My future work will likely involve pharmacogenetics and personalized medicine, with specific focus on Alzheimer’s disease.

Member
Boston University
Evans Center for Interdisciplinary Biomedical Research

Member
Boston University
Genome Science Institute

Graduate Faculty (Primary Mentor of Grad Students)
Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences

BU Research

Genetic Studies of Alzheimer's Disease in Jewish and Arab Populations
09/01/2023 - 08/31/2028 (Multi-PI)
PI: Richard Sherva, PhD
NIH/National Institute on Aging
1U01AG081230-01

Exploring mechanisms driving microbe-induced AD risk using next generation sequence data
09/30/2021 - 05/31/2026 (PI)
NIH/National Institute on Aging
5R01AG076002-04

Personnel Agreement for Research Services of Richard Sherva
07/01/2023 - 06/30/2025 (PI)
VA Boston Healthcare System

Single Cell Analysis for AMD
09/01/2021 - 09/30/2023 (Subcontract PI)
State University of New York at Buffalo Genentech, Inc

Personnel Agreement for Research Services of Richard Sherva
08/01/2018 - 06/30/2022 (PI)
VA Boston Healthcare System

Genetic Architecture of Memory and Executive Functioning in Alzheimer's Disease
09/01/2014 - 05/31/2019 (Subcontract PI)
University of Washington NIH NIA
5R01AG042437-04

Genetics of Rate of Cognitive Decline in a Clinical Trial of AD
11/01/2011 - 10/31/2013 (PI)
Alzheimer's Association

Title

Yr	Title	Project-Sub Proj	Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis Copy PMIDs To Clipboard

Kang M, Li C, Mahajan A, Spat-Lemus J, Durape S, Chen J, Gurnani AS, Devine S, Auerbach SH, Ang TFA, Sherva R, Qiu WQ, Lunetta KL, Au R, Farrer LA, Mez J. Subjective Cognitive Decline Plus and Longitudinal Assessment and Risk for Cognitive Impairment. JAMA Psychiatry. 2024 Jul 03.View Related Profiles.

Gurnani, Ashita
Mez, Jesse
Lunetta, Kathryn
Farrer, Lindsay
Au, Rhoda
Sherva, Richard
Auerbach, Sanford
Devine, Sherral

PMID: 38959008; PMCID: PMC11223054; DOI: 10.1001/jamapsychiatry.2024.1678;

Neale ZE, Fonda JR, Miller MW, Wolf EJ, Zhang R, Sherva R, Harrington KM, Merritt V, Panizzon MS, Hauger RL, Gaziano JM, Logue MW. Subjective cognitive concerns, APOE e4, PTSD symptoms, and risk for dementia among older veterans. Alzheimers Res Ther. 2024 Jun 29; 16(1):143.View Related Profiles.

Wolf, Erika
Gaziano, J. Michael
Fonda, Jennifer
Harrington, Kelly M
Logue, Mark
Miller, Mark
Sherva, Richard

PMID: 38951900; PMCID: PMC11218206; DOI: 10.1186/s13195-024-01512-w;

Belloy ME, Guen YL, Stewart I, Herz J, Sherva R, Zhang R, Merritt V, Panizzon MS, Hauger RL, Gaziano JM, Logue M, Napolioni V, Greicius MD. The Role of X Chromosome in Alzheimer's Disease Genetics. medRxiv. 2024 Apr 23.View Related Profiles.

Logue, Mark
Sherva, Richard

PMID: 38712163; PMCID: PMC11071554; DOI: 10.1101/2024.04.22.24306094;

Zheng Y, Lunetta KL, Liu C, Smith AK, Sherva R, Miller MW, Logue MW. A novel principal component based method for identifying differentially methylated regions in Illumina Infinium MethylationEPIC BeadChip data. Epigenetics. 2023 Dec; 18(1):2207959.View Related Profiles.

Lunetta, Kathryn
Logue, Mark
Miller, Mark
Sherva, Richard

PMID: 37196182; PMCID: PMC10193914; DOI: 10.1080/15592294.2023.2207959;

Shwani T, Zhang C, Owen LA, Shakoor A, Vitale AT, Lillvis JH, Barr JL, Cromwell P, Finley R, Husami N, Au E, Zavala RA, Graves EC, Zhang SX, Farkas MH, Ammar DA, Allison KM, Tawfik A, Sherva RM, Li M, Stambolian D, Kim IK, Farrer LA, DeAngelis MM. Patterns of Gene Expression, Splicing, and Allele-Specific Expression Vary among Macular Tissues and Clinical Stages of Age-Related Macular Degeneration. Cells. 2023 Nov 21; 12(23).View Related Profiles.

Farrer, Lindsay
Sherva, Richard

PMID: 38067097; PMCID: PMC10705168; DOI: 10.3390/cells12232668;

Tejeda M, Farrell J, Zhu C, Wetzler L, Lunetta KL, Bush WS, Martin ER, Wang LS, Schellenberg GD, Pericak-Vance MA, Haines JL, Farrer LA, Sherva R. DNA from multiple viral species is associated with Alzheimer's disease risk. Alzheimers Dement. 2024 Jan; 20(1):253-265.View Related Profiles.

Lunetta, Kathryn
Wetzler, Lee
Farrer, Lindsay
Sherva, Richard

PMID: 37578203; PMCID: PMC10840621; DOI: 10.1002/alz.13414;

Rajabli F, Benchek P, Tosto G, Kushch N, Sha J, Bazemore K, Zhu C, Lee WP, Haut J, Hamilton-Nelson KL, Wheeler NR, Zhao Y, Farrell JJ, Grunin MA, Leung YY, Kuksa PP, Li D, Lucio da Fonseca E, Mez JB, Palmer EL, Pillai J, Sherva RM, Song YE, Zhang X, Iqbal T, Pathak O, Valladares O, Kuzma AB, Abner E, Adams PM, Aguirre A, Albert MS, Albin RL, Allen M, Alvarez L, Apostolova LG, Arnold SE, Asthana S, Atwood CS, Ayres G, Baldwin CT, Barber RC, Barnes LL, Barral S, Beach TG, Becker JT, Beecham GW, Beekly D, Benitez BA, Bennett D, Bertelson J, Bird TD, Blacker D, Boeve BF, Bowen JD, Boxer A, Brewer J, Burke JR, Burns JM, Buxbaum JD, Cairns NJ, Cantwell LB, Cao C, Carlson CS, Carlsson CM, Carney RM, Carrasquillo MM, Chasse S, Chesselet MF, Chin NA, Chui HC, Chung J, Craft S, Crane PK, Cribbs DH, Crocco EA, Cruchaga C, Cuccaro ML, Cullum M, Darby E, Davis B, De Jager PL, DeCarli C, DeToledo J, Dick M, Dickson DW, Dombroski BA, Doody RS, Duara R, Ertekin-Taner N, Evans DA, Faber KM, Fairchild TJ, Fallon KB, Fardo DW, Farlow MR, Fernandez-Hernandez V, Ferris S, Foroud TM, Frosch MP, Fulton-Howard B, Galasko DR, Gamboa A, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Goate AM, Grabowski TJ, Graff-Radford NR, Green RC, Growdon JH, Hakonarson H, Hall J, Hamilton RL, Harari O, Hardy J, Harrell LE, Head E, Henderson VW, Hernandez M, Hohman T, Honig LS, Huebinger RM, Huentelman MJ, Hulette CM, Hyman BT, Hynan LS, Ibanez L, Jarvik GP, Jayadev S, Jin LW, Johnson K, Johnson L, Kamboh MI, Karydas AM, Katz MJ, Kauwe JS, Kaye JA, Keene CD, Khaleeq A, Kim R, Knebl J, Kowall NW, Kramer JH, Kukull WA, LaFerla FM, Lah JJ, Larson EB, Lerner A, Leverenz JB, Levey AI, Lieberman AP, Lipton RB, Logue M, Lopez OL, Lunetta KL, Lyketsos CG, Mains D, Margaret FE, Marson DC, Martin ERR, Martiniuk F, Mash DC, Masliah E, Massman P, Masurkar A, McCormick WC, McCurry SM, McDavid AN, McDonough S, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Montine TJ, Monuki ES, Morris JC, Mukherjee S, Myers AJ, Nguyen T, O'Bryant S, Olichney JM, Ory M, Palmer R, Parisi JE, Paulson HL, Pavlik V, Paydarfar D, Perez V, Peskind E, Petersen RC, Pierce A, Polk M, Poon WW, Potter H, Qu L, Quiceno M, Quinn JF, Raj A, Raskind M, Reiman EM, Reisberg B, Reisch JS, Ringman JM, Roberson ED, Rodriguear M, Rogaeva E, Rosen HJ, Rosenberg RN, Royall DR, Sager MA, Sano M, Saykin AJ, Schneider JA, Schneider LS, Seeley WW, Slifer SH, Small S, Smith AG, Smith JP, Sonnen JA, Spina S, St George-Hyslop P, Stern RA, Stevens AB, Strittmatter SM, Sultzer D, Swerdlow RH, Tanzi RE, Tilson JL, Trojanowski JQ, Troncoso JC, Tsuang DW, Van Deerlin VM, van Eldik LJ, Vance JM, Vardarajan BN, Vassar R, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Whitehead PL, Wijsman EM, Wilhelmsen KC, Williams B, Williamson J, Wilms H, Wingo TS, Wisniewski T, Woltjer RL, Woon M, Wright CB, Wu CK, Younkin SG, Yu CE, Yu L, Zhu X, Kunkle BW, Bush WS, Wang LS, Farrer LA, Haines JL, Mayeux R, Pericak-Vance MA, Schellenberg GD, Jun GR, Reitz C, Naj AC. Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies LRRC4C, LHX5-AS1 and nominates ancestry-specific loci PTPRK , GRB14 , and KIAA0825 as novel risk loci for Alzheimer's disease: the Alzheimer's Disease Genetics Consortium. medRxiv. 2023 Jul 08.View Related Profiles.

McKee, Ann
Jun, Gyungah
Mez, Jesse
Lunetta, Kathryn
Farrer, Lindsay
Logue, Mark
Kowall, Neil
Sherva, Richard
Stern, Robert

PMID: 37461624; PMCID: PMC10350126; DOI: 10.1101/2023.07.06.23292311;

Kang M, Ang TFA, Devine SA, Sherva R, Mukherjee S, Trittschuh EH, Gibbons LE, Scollard P, Lee M, Choi SE, Klinedinst B, Nakano C, Dumitrescu LC, Durant A, Hohman TJ, Cuccaro ML, Saykin AJ, Kukull WA, Bennett DA, Wang LS, Mayeux RP, Haines JL, Pericak-Vance MA, Schellenberg GD, Crane PK, Au R, Lunetta KL, Mez JB, Farrer LA. A genome-wide search for pleiotropy in more than 100,000 harmonized longitudinal cognitive domain scores. Mol Neurodegener. 2023 Jun 22; 18(1):40.View Related Profiles.

Mez, Jesse
Lunetta, Kathryn
Farrer, Lindsay
Au, Rhoda
Sherva, Richard
Devine, Sherral
Ang, Ting Fang Alvin

PMID: 37349795; PMCID: PMC10286470; DOI: 10.1186/s13024-023-00633-4;

Orozco LD, Owen LA, Hofmann J, Stockwell AD, Tao J, Haller S, Mukundan VT, Clarke C, Lund J, Sridhar A, Mayba O, Barr JL, Zavala RA, Graves EC, Zhang C, Husami N, Finley R, Au E, Lillvis JH, Farkas MH, Shakoor A, Sherva R, Kim IK, Kaminker JS, Townsend MJ, Farrer LA, Yaspan BL, Chen HH, DeAngelis MM. A systems biology approach uncovers novel disease mechanisms in age-related macular degeneration. Cell Genom. 2023 Jun 14; 3(6):100302.View Related Profiles.

Farrer, Lindsay
Sherva, Richard

PMID: 37388919; PMCID: PMC10300496; DOI: 10.1016/j.xgen.2023.100302;

Barr JL, Feehan M, Tak C, Owen LA, Finley RC, Cromwell PA, Lillvis JH, Hicks PM, Au E, Farkas MH, Weiner A, Reynolds AL, Sieminski SF, Sherva RM, Munger MA, Brilliant MH, DeAngelis MM. Heritable Risk and Protective Genetic Components of Glaucoma Medication Non-Adherence. Int J Mol Sci. 2023 Mar 15; 24(6). PMID: 36982708; PMCID: PMC10058353; DOI: 10.3390/ijms24065636;

Showing 10 of 81 results. Show More

Le Guen Y, Raulin AC, Logue MW, Sherva R, Belloy ME, Eger SJ, Chen A, Kennedy G, Kuchenbecker L, O'Leary JP, Zhang R, Merritt VC, Panizzon MS, Hauger RL, Gaziano JM, Bu G, Thornton TA, Farrer LA, Napolioni V, He Z, Greicius MD. Association of African Ancestry-Specific APOE Missense Variant R145C With Risk of Alzheimer Disease. JAMA. 2023 Feb 21; 329(7):551-560.View Related Profiles.

Gaziano, J. Michael
Farrer, Lindsay
Logue, Mark
Sherva, Richard

PMID: 36809323; PMCID: PMC9945061; DOI: 10.1001/jama.2023.0268;

Hayes JP, Pierce ME, Brown E, Salat D, Logue MW, Constantinescu J, Valerio K, Miller MW, Sherva R, Huber BR, Milberg W, McGlinchey R. Genetic Risk for Alzheimer Disease and Plasma Tau Are Associated With Accelerated Parietal Cortex Thickness Change in Middle-Aged Adults. Neurol Genet. 2023 Feb; 9(1):e200053.View Related Profiles.

Huber, Bertrand
Hayes, Jasmeet
Logue, Mark
Miller, Mark
McGlinchey, Regina
Sherva, Richard
Milberg, William

PMID: 36742995; PMCID: PMC9893442; DOI: 10.1212/NXG.0000000000200053;

Sherva R, Zhang R, Sahelijo N, Jun G, Anglin T, Chanfreau C, Cho K, Fonda JR, Gaziano JM, Harrington KM, Ho YL, Kremen WS, Litkowski E, Lynch J, Neale Z, Roussos P, Marra D, Mez J, Miller MW, Salat DH, Tsuang D, Wolf E, Zeng Q, Panizzon MS, Merritt VC, Farrer LA, Hauger RL, Logue MW. African ancestry GWAS of dementia in a large military cohort identifies significant risk loci. Mol Psychiatry. 2023 Mar; 28(3):1293-1302.View Related Profiles.

Marra, David
Wolf, Erika
Jun, Gyungah
Gaziano, J. Michael
Fonda, Jennifer
Mez, Jesse
Harrington, Kelly M
Farrer, Lindsay
Logue, Mark
Miller, Mark
Sherva, Richard
Neale, Zoe

PMID: 36543923; PMCID: PMC10066923; DOI: 10.1038/s41380-022-01890-3;

Logue MW, Miller MW, Sherva R, Zhang R, Harrington KM, Fonda JR, Merritt VC, Panizzon MS, Hauger RL, Wolf EJ, Neale Z, Gaziano JM. Alzheimer's disease and related dementias among aging veterans: Examining gene-by-environment interactions with post-traumatic stress disorder and traumatic brain injury. Alzheimers Dement. 2023 Jun; 19(6):2549-2559.View Related Profiles.

Wolf, Erika
Gaziano, J. Michael
Fonda, Jennifer
Harrington, Kelly M
Logue, Mark
Miller, Mark
Sherva, Richard

PMID: 36546606; PMCID: PMC10271966; DOI: 10.1002/alz.12870;

Gaddis N, Mathur R, Marks J, Zhou L, Quach B, Waldrop A, Levran O, Agrawal A, Randesi M, Adelson M, Jeffries PW, Martin NG, Degenhardt L, Montgomery GW, Wetherill L, Lai D, Bucholz K, Foroud T, Porjesz B, Runarsdottir V, Tyrfingsson T, Einarsson G, Gudbjartsson DF, Webb BT, Crist RC, Kranzler HR, Sherva R, Zhou H, Hulse G, Wildenauer D, Kelty E, Attia J, Holliday EG, McEvoy M, Scott RJ, Schwab SG, Maher BS, Gruza R, Kreek MJ, Nelson EC, Thorgeirsson T, Stefansson K, Berrettini WH, Gelernter J, Edenberg HJ, Bierut L, Hancock DB, Johnson EO. Multi-trait genome-wide association study of opioid addiction: OPRM1 and beyond. Sci Rep. 2022 Oct 07; 12(1):16873. PMID: 36207451; PMCID: PMC9546890; DOI: 10.1038/s41598-022-21003-y;

Cox J, Sherva R, Wetherill L, Foroud T, Edenberg HJ, Kranzler HR, Gelernter J, Farrer LA. Genome-wide association study of stimulant dependence. Transl Psychiatry. 2021 06 29; 11(1):363.View Related Profiles.

Farrer, Lindsay
Sherva, Richard

PMID: 34226506; PMCID: PMC8257618; DOI: 10.1038/s41398-021-01440-5;

Sherva R, Zhu C, Wetherill L, Edenberg HJ, Johnson E, Degenhardt L, Agrawal A, Martin NG, Nelson E, Kranzler HR, Gelernter J, Farrer LA. Genome-wide association study of phenotypes measuring progression from first cocaine or opioid use to dependence reveals novel risk genes. Explor Med. 2021; 2:60-73.View Related Profiles.

Farrer, Lindsay
Sherva, Richard

PMID: 34124712; PMCID: PMC8192073; DOI: 10.37349/emed.2021.00032;

Quach BC, Bray MJ, Gaddis NC, Liu M, Palviainen T, Minica CC, Zellers S, Sherva R, Aliev F, Nothnagel M, Young KA, Marks JA, Young H, Carnes MU, Guo Y, Waldrop A, Sey NYA, Landi MT, McNeil DW, Drichel D, Farrer LA, Markunas CA, Vink JM, Hottenga JJ, Iacono WG, Kranzler HR, Saccone NL, Neale MC, Madden P, Rietschel M, Marazita ML, McGue M, Won H, Winterer G, Grucza R, Dick DM, Gelernter J, Caporaso NE, Baker TB, Boomsma DI, Kaprio J, Hokanson JE, Vrieze S, Bierut LJ, Johnson EO, Hancock DB. Expanding the genetic architecture of nicotine dependence and its shared genetics with multiple traits. Nat Commun. 2020 11 03; 11(1):5562.View Related Profiles.

Farrer, Lindsay
Sherva, Richard

PMID: 33144568; PMCID: PMC7642344; DOI: 10.1038/s41467-020-19265-z;

Johnson EC, Demontis D, Thorgeirsson TE, Walters RK, Polimanti R, Hatoum AS, Sanchez-Roige S, Paul SE, Wendt FR, Clarke TK, Lai D, Reginsson GW, Zhou H, He J, Baranger DAA, Gudbjartsson DF, Wedow R, Adkins DE, Adkins AE, Alexander J, Bacanu SA, Bigdeli TB, Boden J, Brown SA, Bucholz KK, Bybjerg-Grauholm J, Corley RP, Degenhardt L, Dick DM, Domingue BW, Fox L, Goate AM, Gordon SD, Hack LM, Hancock DB, Hartz SM, Hickie IB, Hougaard DM, Krauter K, Lind PA, McClintick JN, McQueen MB, Meyers JL, Montgomery GW, Mors O, Mortensen PB, Nordentoft M, Pearson JF, Peterson RE, Reynolds MD, Rice JP, Runarsdottir V, Saccone NL, Sherva R, Silberg JL, Tarter RE, Tyrfingsson T, Wall TL, Webb BT, Werge T, Wetherill L, Wright MJ, Zellers S, Adams MJ, Bierut LJ, Boardman JD, Copeland WE, Farrer LA, Foroud TM, Gillespie NA, Grucza RA, Harris KM, Heath AC, Hesselbrock V, Hewitt JK, Hopfer CJ, Horwood J, Iacono WG, Johnson EO, Kendler KS, Kennedy MA, Kranzler HR, Madden PAF, Maes HH, Maher BS, Martin NG, McGue M, McIntosh AM, Medland SE, Nelson EC, Porjesz B, Riley BP, Stallings MC, Vanyukov MM, Vrieze S, Davis LK, Bogdan R, Gelernter J, Edenberg HJ, Stefansson K, Børglum AD, Agrawal A. A large-scale genome-wide association study meta-analysis of cannabis use disorder. Lancet Psychiatry. 2020 12; 7(12):1032-1045.View Related Profiles.

Farrer, Lindsay
Sherva, Richard

PMID: 33096046; PMCID: PMC7674631; DOI: 10.1016/S2215-0366(20)30339-4;

Zhou H, Rentsch CT, Cheng Z, Kember RL, Nunez YZ, Sherva RM, Tate JP, Dao C, Xu K, Polimanti R, Farrer LA, Justice AC, Kranzler HR, Gelernter J. Association of OPRM1 Functional Coding Variant With Opioid Use Disorder: A Genome-Wide Association Study. JAMA Psychiatry. 2020 10 01; 77(10):1072-1080.View Related Profiles.

Farrer, Lindsay
Sherva, Richard

PMID: 32492095; PMCID: PMC7270886; DOI: 10.1001/jamapsychiatry.2020.1206;

Sherva R, Gross A, Mukherjee S, Koesterer R, Amouyel P, Bellenguez C, Dufouil C, Bennett DA, Chibnik L, Cruchaga C, Del-Aguila J, Farrer LA, Mayeux R, Munsie L, Winslow A, Newhouse S, Saykin AJ, Kauwe JSK, Crane PK, Green RC. Genome-wide association study of rate of cognitive decline in Alzheimer's disease patients identifies novel genes and pathways. Alzheimers Dement. 2020 08; 16(8):1134-1145.View Related Profiles.

Farrer, Lindsay
Chibnik, Lori
Sherva, Richard

PMID: 32573913; PMCID: PMC7924136; DOI: 10.1002/alz.12106;

Chen J, Loukola A, Gillespie NA, Peterson R, Jia P, Riley B, Maes H, Dick DM, Kendler KS, Damaj MI, Miles MF, Zhao Z, Li MD, Vink JM, Minica CC, Willemsen G, Boomsma DI, Qaiser B, Madden PAF, Korhonen T, Jousilahti P, Hällfors J, Gelernter J, Kranzler HR, Sherva R, Farrer L, Maher B, Vanyukov M, Taylor M, Ware JJ, Munafò MR, Lutz SM, Hokanson JE, Gu F, Landi MT, Caporaso NE, Hancock DB, Gaddis NC, Baker TB, Bierut LJ, Johnson EO, Chenoweth M, Lerman C, Tyndale R, Kaprio J, Chen X. Genome-Wide Meta-Analyses of FTND and TTFC Phenotypes. Nicotine Tob Res. 2020 05 26; 22(6):900-909.View Related Profiles.

Farrer, Lindsay
Sherva, Richard

PMID: 31294817; PMCID: PMC7249921; DOI: 10.1093/ntr/ntz099;

Cox JW, Sherva RM, Lunetta KL, Saitz R, Kon M, Kranzler HR, Gelernter J, Farrer LA. Identifying factors associated with opioid cessation in a biracial sample using machine learning. Explor Med. 2020; 1(1):27-41.View Related Profiles.

Lunetta, Kathryn
Farrer, Lindsay
Saitz, Richard
Sherva, Richard

PMID: 33554217; PMCID: PMC7861053; DOI: 10.37349/emed.2020.00003;

Munn-Chernoff MA, Johnson EC, Chou YL, Coleman JRI, Thornton LM, Walters RK, Yilmaz Z, Baker JH, Hübel C, Gordon S, Medland SE, Watson HJ, Gaspar HA, Bryois J, Hinney A, Leppä VM, Mattheisen M, Ripke S, Yao S, Giusti-Rodríguez P, Hanscombe KB, Adan RAH, Alfredsson L, Ando T, Andreassen OA, Berrettini WH, Boehm I, Boni C, Boraska Perica V, Buehren K, Burghardt R, Cassina M, Cichon S, Clementi M, Cone RD, Courtet P, Crow S, Crowley JJ, Danner UN, Davis OSP, de Zwaan M, Dedoussis G, Degortes D, DeSocio JE, Dick DM, Dikeos D, Dina C, Dmitrzak-Weglarz M, Docampo E, Duncan LE, Egberts K, Ehrlich S, Escaramís G, Esko T, Estivill X, Farmer A, Favaro A, Fernández-Aranda F, Fichter MM, Fischer K, Föcker M, Foretova L, Forstner AJ, Forzan M, Franklin CS, Gallinger S, Giegling I, Giuranna J, Gonidakis F, Gorwood P, Gratacos Mayora M, Guillaume S, Guo Y, Hakonarson H, Hatzikotoulas K, Hauser J, Hebebrand J, Helder SG, Herms S, Herpertz-Dahlmann B, Herzog W, Huckins LM, Hudson JI, Imgart H, Inoko H, Janout V, Jiménez-Murcia S, Julià A, Kalsi G, Kaminská D, Karhunen L, Karwautz A, Kas MJH, Kennedy JL, Keski-Rahkonen A, Kiezebrink K, Kim YR, Klump KL, Knudsen GPS, La Via MC, Le Hellard S, Levitan RD, Li D, Lilenfeld L, Lin BD, Lissowska J, Luykx J, Magistretti PJ, Maj M, Mannik K, Marsal S, Marshall CR, Mattingsdal M, McDevitt S, McGuffin P, Metspalu A, Meulenbelt I, Micali N, Mitchell K, Monteleone AM, Monteleone P, Nacmias B, Navratilova M, Ntalla I, O'Toole JK, Ophoff RA, Padyukov L, Palotie A, Pantel J, Papezova H, Pinto D, Rabionet R, Raevuori A, Ramoz N, Reichborn-Kjennerud T, Ricca V, Ripatti S, Ritschel F, Roberts M, Rotondo A, Rujescu D, Rybakowski F, Santonastaso P, Scherag A, Scherer SW, Schmidt U, Schork NJ, Schosser A, Seitz J, Slachtova L, Slagboom PE, Slof-Op't Landt MCT, Slopien A, Sorbi S, Swiatkowska B, Szatkiewicz JP, Tachmazidou I, Tenconi E, Tortorella A, Tozzi F, Treasure J, Tsitsika A, Tyszkiewicz-Nwafor M, Tziouvas K, van Elburg AA, van Furth EF, Wagner G, Walton E, Widen E, Zeggini E, Zerwas S, Zipfel S, Bergen AW, Boden JM, Brandt H, Crawford S, Halmi KA, Horwood LJ, Johnson C, Kaplan AS, Kaye WH, Mitchell J, Olsen CM, Pearson JF, Pedersen NL, Strober M, Werge T, Whiteman DC, Woodside DB, Grove J, Henders AK, Larsen JT, Parker R, Petersen LV, Jordan J, Kennedy MA, Birgegård A, Lichtenstein P, Norring C, Landén M, Mortensen PB, Polimanti R, McClintick JN, Adkins AE, Aliev F, Bacanu SA, Batzler A, Bertelsen S, Biernacka JM, Bigdeli TB, Chen LS, Clarke TK, Degenhardt F, Docherty AR, Edwards AC, Foo JC, Fox L, Frank J, Hack LM, Hartmann AM, Hartz SM, Heilmann-Heimbach S, Hodgkinson C, Hoffmann P, Hottenga JJ, Konte B, Lahti J, Lahti-Pulkkinen M, Lai D, Ligthart L, Loukola A, Maher BS, Mbarek H, McIntosh AM, McQueen MB, Meyers JL, Milaneschi Y, Palviainen T, Peterson RE, Ryu E, Saccone NL, Salvatore JE, Sanchez-Roige S, Schwandt M, Sherva R, Streit F, Strohmaier J, Thomas N, Wang JC, Webb BT, Wedow R, Wetherill L, Wills AG, Zhou H, Boardman JD, Chen D, Choi DS, Copeland WE, Culverhouse RC, Dahmen N, Degenhardt L, Domingue BW, Frye MA, Gäebel W, Hayward C, Ising M, Keyes M, Kiefer F, Koller G, Kramer J, Kuperman S, Lucae S, Lynskey MT, Maier W, Mann K, Männistö S, Müller-Myhsok B, Murray AD, Nurnberger JI, Preuss U, Räikkönen K, Reynolds MD, Ridinger M, Scherbaum N, Schuckit MA, Soyka M, Treutlein J, Witt SH, Wodarz N, Zill P, Adkins DE, Boomsma DI, Bierut LJ, Brown SA, Bucholz KK, Costello EJ, de Wit H, Diazgranados N, Eriksson JG, Farrer LA, Foroud TM, Gillespie NA, Goate AM, Goldman D, Grucza RA, Hancock DB, Harris KM, Hesselbrock V, Hewitt JK, Hopfer CJ, Iacono WG, Johnson EO, Karpyak VM, Kendler KS, Kranzler HR, Krauter K, Lind PA, McGue M, MacKillop J, Madden PAF, Maes HH, Magnusson PKE, Nelson EC, Nöthen MM, Palmer AA, Penninx BWJH, Porjesz B, Rice JP, Rietschel M, Riley BP, Rose RJ, Shen PH, Silberg J, Stallings MC, Tarter RE, Vanyukov MM, Vrieze S, Wall TL, Whitfield JB, Zhao H, Neale BM, Wade TD, et al. Shared geView Related Profiles.

Farrer, Lindsay
Sherva, Richard

PMID: 32064741; PMCID: PMC7429266; DOI: 10.1111/adb.12880;

Cox JW, Sherva RM, Lunetta KL, Johnson EC, Martin NG, Degenhardt L, Agrawal A, Nelson EC, Kranzler HR, Gelernter J, Farrer LA. Genome-Wide Association Study of Opioid Cessation. J Clin Med. 2020 Jan 09; 9(1).View Related Profiles.

Lunetta, Kathryn
Farrer, Lindsay
Sherva, Richard

PMID: 31936517; PMCID: PMC7019731; DOI: 10.3390/jcm9010180;

Marees AT, Gamazon ER, Gerring Z, Vorspan F, Fingal J, van den Brink W, Smit DJA, Verweij KJH, Kranzler HR, Sherva R, Farrer L, Gelernter J, Derks EM. Post-GWAS analysis of six substance use traits improves the identification and functional interpretation of genetic risk loci. Drug Alcohol Depend. 2020 01 01; 206:107703.View Related Profiles.

Farrer, Lindsay
Sherva, Richard

PMID: 31785998; PMCID: PMC9159918; DOI: 10.1016/j.drugalcdep.2019.107703;

Walters RK, Polimanti R, Johnson EC, McClintick JN, Adams MJ, Adkins AE, Aliev F, Bacanu SA, Batzler A, Bertelsen S, Biernacka JM, Bigdeli TB, Chen LS, Clarke TK, Chou YL, Degenhardt F, Docherty AR, Edwards AC, Fontanillas P, Foo JC, Fox L, Frank J, Giegling I, Gordon S, Hack LM, Hartmann AM, Hartz SM, Heilmann-Heimbach S, Herms S, Hodgkinson C, Hoffmann P, Jan Hottenga J, Kennedy MA, Alanne-Kinnunen M, Konte B, Lahti J, Lahti-Pulkkinen M, Lai D, Ligthart L, Loukola A, Maher BS, Mbarek H, McIntosh AM, McQueen MB, Meyers JL, Milaneschi Y, Palviainen T, Pearson JF, Peterson RE, Ripatti S, Ryu E, Saccone NL, Salvatore JE, Sanchez-Roige S, Schwandt M, Sherva R, Streit F, Strohmaier J, Thomas N, Wang JC, Webb BT, Wedow R, Wetherill L, Wills AG, Boardman JD, Chen D, Choi DS, Copeland WE, Culverhouse RC, Dahmen N, Degenhardt L, Domingue BW, Elson SL, Frye MA, Gäbel W, Hayward C, Ising M, Keyes M, Kiefer F, Kramer J, Kuperman S, Lucae S, Lynskey MT, Maier W, Mann K, Männistö S, Müller-Myhsok B, Murray AD, Nurnberger JI, Palotie A, Preuss U, Räikkönen K, Reynolds MD, Ridinger M, Scherbaum N, Schuckit MA, Soyka M, Treutlein J, Witt S, Wodarz N, Zill P, Adkins DE, Boden JM, Boomsma DI, Bierut LJ, Brown SA, Bucholz KK, Cichon S, Costello EJ, de Wit H, Diazgranados N, Dick DM, Eriksson JG, Farrer LA, Foroud TM, Gillespie NA, Goate AM, Goldman D, Grucza RA, Hancock DB, Harris KM, Heath AC, Hesselbrock V, Hewitt JK, Hopfer CJ, Horwood J, Iacono W, Johnson EO, Kaprio JA, Karpyak VM, Kendler KS, Kranzler HR, Krauter K, Lichtenstein P, Lind PA, McGue M, MacKillop J, Madden PAF, Maes HH, Magnusson P, Martin NG, Medland SE, Montgomery GW, Nelson EC, Nöthen MM, Palmer AA, Pedersen NL, Penninx BWJH, Porjesz B, Rice JP, Rietschel M, Riley BP, Rose R, Rujescu D, Shen PH, Silberg J, Stallings MC, Tarter RE, Vanyukov MM, Vrieze S, Wall TL, Whitfield JB, Zhao H, Neale BM, Gelernter J, Edenberg HJ, Agrawal A. Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders. Nat Neurosci. 2018 12; 21(12):1656-1669.View Related Profiles.

Farrer, Lindsay
Sherva, Richard

PMID: 30482948; PMCID: PMC6430207; DOI: 10.1038/s41593-018-0275-1;

Minica CC, Verweij KJH, van der Most PJ, Mbarek H, Bernard M, van Eijk KR, Lind PA, Liu MZ, Maciejewski DF, Palviainen T, Sánchez-Mora C, Sherva R, Taylor M, Walters RK, Abdellaoui A, Bigdeli TB, Branje SJT, Brown SA, Casas M, Corley RP, Davey-Smith G, Davies GE, Ehli EA, Farrer L, Fedko IO, Garcia-Martínez I, Gordon SD, Hartman CA, Heath AC, Hickie IB, Hickman M, Hopfer CJ, Hottenga JJ, Kahn RS, Kaprio J, Korhonen T, Kranzler HR, Krauter K, van Lier PAC, Madden PAF, Medland SE, Neale MC, Meeus WHJ, Montgomery GW, Nolte IM, Oldehinkel AJ, Pausova Z, Ramos-Quiroga JA, Richarte V, Rose RJ, Shin J, Stallings MC, Wall TL, Ware JJ, Wright MJ, Zhao H, Koot HM, Paus T, Hewitt JK, Ribasés M, Loukola A, Boks MP, Snieder H, Munafò MR, Gelernter J, Boomsma DI, Martin NG, Gillespie NA, Vink JM, Derks EM. Genome-wide association meta-analysis of age at first cannabis use. Addiction. 2018 11; 113(11):2073-2086.View Related Profiles.

Farrer, Lindsay
Sherva, Richard

PMID: 30003630; PMCID: PMC7087375; DOI: 10.1111/add.14368;

Datta S, Sherva RM, De La Cruz M, Long MT, Roy P, Backman V, Chowdhury S, Roy HK. Single Nucleotide Polymorphism Facilitated Down-Regulation of the Cohesin Stromal Antigen-1: Implications for Colorectal Cancer Racial Disparities. Neoplasia. 2018 03; 20(3):289-294.View Related Profiles.

Roy, Hemant
Long, Michelle
Sherva, Richard
Chowdhury, Sanjib
Datta, Somenath

PMID: 29471289; PMCID: PMC5883624; DOI: 10.1016/j.neo.2018.01.003;

Cheng Z, Zhou H, Sherva R, Farrer LA, Kranzler HR, Gelernter J. Genome-wide Association Study Identifies a Regulatory Variant of RGMA Associated With Opioid Dependence in European Americans. Biol Psychiatry. 2018 11 15; 84(10):762-770.View Related Profiles.

Farrer, Lindsay
Sherva, Richard

PMID: 29478698; PMCID: PMC6041180; DOI: 10.1016/j.biopsych.2017.12.016;

Chung J, Wang X, Maruyama T, Ma Y, Zhang X, Mez J, Sherva R, Takeyama H, Lunetta KL, Farrer LA, Jun GR. Genome-wide association study of Alzheimer's disease endophenotypes at prediagnosis stages. Alzheimers Dement. 2018 05; 14(5):623-633.View Related Profiles.

Jun, Gyungah
Chung, Jaeyoon
Mez, Jesse
Lunetta, Kathryn
Farrer, Lindsay
Sherva, Richard
Zhang, Xiaoling

PMID: 29274321; PMCID: PMC5938137; DOI: 10.1016/j.jalz.2017.11.006;

Zhou H, Polimanti R, Yang BZ, Wang Q, Han S, Sherva R, Nuñez YZ, Zhao H, Farrer LA, Kranzler HR, Gelernter J. Genetic Risk Variants Associated With Comorbid Alcohol Dependence and Major Depression. JAMA Psychiatry. 2017 Dec 01; 74(12):1234-1241.View Related Profiles.

Farrer, Lindsay
Sherva, Richard

PMID: 29071344; PMCID: PMC6331050; DOI: 10.1001/jamapsychiatry.2017.3275;

Agrawal A, Chou YL, Carey CE, Baranger DAA, Zhang B, Sherva R, Wetherill L, Kapoor M, Wang JC, Bertelsen S, Anokhin AP, Hesselbrock V, Kramer J, Lynskey MT, Meyers JL, Nurnberger JI, Rice JP, Tischfield J, Bierut LJ, Degenhardt L, Farrer LA, Gelernter J, Hariri AR, Heath AC, Kranzler HR, Madden PAF, Martin NG, Montgomery GW, Porjesz B, Wang T, Whitfield JB, Edenberg HJ, Foroud T, Goate AM, Bogdan R, Nelson EC. Genome-wide association study identifies a novel locus for cannabis dependence. Mol Psychiatry. 2018 05; 23(5):1293-1302.View Related Profiles.

Farrer, Lindsay
Sherva, Richard

PMID: 29112194; PMCID: PMC5938138; DOI: 10.1038/mp.2017.200;

Hancock DB, Guo Y, Reginsson GW, Gaddis NC, Lutz SM, Sherva R, Loukola A, Minica CC, Markunas CA, Han Y, Young KA, Gudbjartsson DF, Gu F, McNeil DW, Qaiser B, Glasheen C, Olson S, Landi MT, Madden PAF, Farrer LA, Vink J, Saccone NL, Neale MC, Kranzler HR, McKay J, Hung RJ, Amos CI, Marazita ML, Boomsma DI, Baker TB, Gelernter J, Kaprio J, Caporaso NE, Thorgeirsson TE, Hokanson JE, Bierut LJ, Stefansson K, Johnson EO. Genome-wide association study across European and African American ancestries identifies a SNP in DNMT3B contributing to nicotine dependence. Mol Psychiatry. 2018 09; 23(9):1911-1919.View Related Profiles.

Farrer, Lindsay
Sherva, Richard

PMID: 28972577; PMCID: PMC5882602; DOI: 10.1038/mp.2017.193;

Sippel LM, Han S, Watkins LE, Harpaz-Rotem I, Southwick SM, Krystal JH, Olff M, Sherva R, Farrer LA, Kranzler HR, Gelernter J, Pietrzak RH. Oxytocin receptor gene polymorphisms, attachment, and PTSD: Results from the National Health and Resilience in Veterans Study. J Psychiatr Res. 2017 Nov; 94:139-147.View Related Profiles.

Farrer, Lindsay
Sherva, Richard

PMID: 28715704; PMCID: PMC5605420; DOI: 10.1016/j.jpsychires.2017.07.008;

Polimanti R, Meda SA, Pearlson GD, Zhao H, Sherva R, Farrer LA, Kranzler HR, Gelernter J. S100A10 identified in a genome-wide gene × cannabis dependence interaction analysis of risky sexual behaviours. J Psychiatry Neurosci. 2017 Jun; 42(4):252-261.View Related Profiles.

Farrer, Lindsay
Sherva, Richard

PMID: 28418321; PMCID: PMC5487272; DOI: 10.1503/jpn.160189;

Adkins AE, Hack LM, Bigdeli TB, Williamson VS, McMichael GO, Mamdani M, Edwards AC, Aliev F, Chan RF, Bhandari P, Raabe RC, Alaimo JT, Blackwell GG, Moscati A, Poland RS, Rood B, Patterson DG, Walsh D, Whitfield JB, Zhu G, Montgomery GW, Henders AK, Martin NG, Heath AC, Madden PAF, Frank J, Ridinger M, Wodarz N, Soyka M, Zill P, Ising M, Nöthen MM, Kiefer F, Rietschel M, Gelernter J, Sherva R, Koesterer R, Almasy L, Zhao H, Kranzler HR, Farrer LA, Maher BS, Prescott CA, Dick DM, Bacanu SA, Mathies LD, Davies AG, Vladimirov VI, Grotewiel M, Bowers MS, Bettinger JC, Webb BT, Miles MF, Kendler KS, Riley BP. Genomewide Association Study of Alcohol Dependence Identifies Risk Loci Altering Ethanol-Response Behaviors in Model Organisms. Alcohol Clin Exp Res. 2017 May; 41(5):911-928.View Related Profiles.

Farrer, Lindsay
Sherva, Richard

PMID: 28226201; PMCID: PMC5404949; DOI: 10.1111/acer.13362;

Jun GR, Chung J, Mez J, Barber R, Beecham GW, Bennett DA, Buxbaum JD, Byrd GS, Carrasquillo MM, Crane PK, Cruchaga C, De Jager P, Ertekin-Taner N, Evans D, Fallin MD, Foroud TM, Friedland RP, Goate AM, Graff-Radford NR, Hendrie H, Hall KS, Hamilton-Nelson KL, Inzelberg R, Kamboh MI, Kauwe JSK, Kukull WA, Kunkle BW, Kuwano R, Larson EB, Logue MW, Manly JJ, Martin ER, Montine TJ, Mukherjee S, Naj A, Reiman EM, Reitz C, Sherva R, St George-Hyslop PH, Thornton T, Younkin SG, Vardarajan BN, Wang LS, Wendlund JR, Winslow AR, Haines J, Mayeux R, Pericak-Vance MA, Schellenberg G, Lunetta KL, Farrer LA. Transethnic genome-wide scan identifies novel Alzheimer's disease loci. Alzheimers Dement. 2017 Jul; 13(7):727-738.View Related Profiles.

Jun, Gyungah
Chung, Jaeyoon
Mez, Jesse
Lunetta, Kathryn
Farrer, Lindsay
Logue, Mark
Sherva, Richard

PMID: 28183528; PMCID: PMC5496797; DOI: 10.1016/j.jalz.2016.12.012;

Wachman EM, Hayes MJ, Sherva R, Brown MS, Shrestha H, Logan BA, Heller NA, Nielsen DA, Farrer LA. Association of maternal and infant variants in PNOC and COMT genes with neonatal abstinence syndrome severity. Am J Addict. 2017 Jan; 26(1):42-49.View Related Profiles.

Wachman, Elisha
Farrer, Lindsay
Sherva, Richard

PMID: 27983768; PMCID: PMC5206487; DOI: 10.1111/ajad.12483;

Mez J, Chung J, Jun G, Kriegel J, Bourlas AP, Sherva R, Logue MW, Barnes LL, Bennett DA, Buxbaum JD, Byrd GS, Crane PK, Ertekin-Taner N, Evans D, Fallin MD, Foroud T, Goate A, Graff-Radford NR, Hall KS, Kamboh MI, Kukull WA, Larson EB, Manly JJ, Haines JL, Mayeux R, Pericak-Vance MA, Schellenberg GD, Lunetta KL, Farrer LA. Two novel loci, COBL and SLC10A2, for Alzheimer's disease in African Americans. Alzheimers Dement. 2017 Feb; 13(2):119-129.View Related Profiles.

Jun, Gyungah
Chung, Jaeyoon
Mez, Jesse
Lunetta, Kathryn
Farrer, Lindsay
Logue, Mark
Sherva, Richard

PMID: 27770636; PMCID: PMC5318231; DOI: 10.1016/j.jalz.2016.09.002;

Sherva R, Wang Q, Kranzler H, Zhao H, Koesterer R, Herman A, Farrer LA, Gelernter J. Genome-wide Association Study of Cannabis Dependence Severity, Novel Risk Variants, and Shared Genetic Risks. JAMA Psychiatry. 2016 May 01; 73(5):472-80.View Related Profiles.

Farrer, Lindsay
Sherva, Richard

PMID: 27028160; PMCID: PMC4974817; DOI: 10.1001/jamapsychiatry.2016.0036;

Stringer S, Minica CC, Verweij KJ, Mbarek H, Bernard M, Derringer J, van Eijk KR, Isen JD, Loukola A, Maciejewski DF, Mihailov E, van der Most PJ, Sánchez-Mora C, Roos L, Sherva R, Walters R, Ware JJ, Abdellaoui A, Bigdeli TB, Branje SJ, Brown SA, Bruinenberg M, Casas M, Esko T, Garcia-Martinez I, Gordon SD, Harris JM, Hartman CA, Henders AK, Heath AC, Hickie IB, Hickman M, Hopfer CJ, Hottenga JJ, Huizink AC, Irons DE, Kahn RS, Korhonen T, Kranzler HR, Krauter K, van Lier PA, Lubke GH, Madden PA, Mägi R, McGue MK, Medland SE, Meeus WH, Miller MB, Montgomery GW, Nivard MG, Nolte IM, Oldehinkel AJ, Pausova Z, Qaiser B, Quaye L, Ramos-Quiroga JA, Richarte V, Rose RJ, Shin J, Stallings MC, Stiby AI, Wall TL, Wright MJ, Koot HM, Paus T, Hewitt JK, Ribasés M, Kaprio J, Boks MP, Snieder H, Spector T, Munafò MR, Metspalu A, Gelernter J, Boomsma DI, Iacono WG, Martin NG, Gillespie NA, Derks EM, Vink JM. Genome-wide association study of lifetime cannabis use based on a large meta-analytic sample of 32 330 subjects from the International Cannabis Consortium. Transl Psychiatry. 2016 Mar 29; 6:e769. PMID: 27023175; PMCID: PMC4872459; DOI: 10.1038/tp.2016.36;

Mez J, Mukherjee S, Thornton T, Fardo DW, Trittschuh E, Sutti S, Sherva R, Kauwe JS, Naj AC, Beecham GW, Gross A, Saykin AJ, Green RC, Crane PK. The executive prominent/memory prominent spectrum in Alzheimer's disease is highly heritable. Neurobiol Aging. 2016 May; 41:115-21.View Related Profiles.

Mez, Jesse
Sherva, Richard

PMID: 27103524; PMCID: PMC4843522; DOI: 10.1016/j.neurobiolaging.2016.02.015;

Hancock DB, Reginsson GW, Gaddis NC, Chen X, Saccone NL, Lutz SM, Qaiser B, Sherva R, Steinberg S, Zink F, Stacey SN, Glasheen C, Chen J, Gu F, Frederiksen BN, Loukola A, Gudbjartsson DF, Brüske I, Landi MT, Bickeböller H, Madden P, Farrer L, Kaprio J, Kranzler HR, Gelernter J, Baker TB, Kraft P, Amos CI, Caporaso NE, Hokanson JE, Bierut LJ, Thorgeirsson TE, Johnson EO, Stefansson K. Genome-wide meta-analysis reveals common splice site acceptor variant in CHRNA4 associated with nicotine dependence. Transl Psychiatry. 2015; 5:e651.View Related Profiles.

Farrer, Lindsay
Sherva, Richard

PMID: 26440539; PMCID: PMC4930126; DOI: 10.1038/tp.2015.149;

Mbarek H, Milaneschi Y, Fedko IO, Hottenga JJ, de Moor MH, Jansen R, Gelernter J, Sherva R, Willemsen G, Boomsma DI, Penninx BW, Vink JM. The genetics of alcohol dependence: Twin and SNP-based heritability, and genome-wide association study based on AUDIT scores. Am J Med Genet B Neuropsychiatr Genet. 2015 Dec; 168(8):739-48. PMID: 26365420; DOI: 10.1002/ajmg.b.32379;

Nelson EC, Agrawal A, Heath AC, Bogdan R, Sherva R, Zhang B, Al-Hasani R, Bruchas MR, Chou YL, Demers CH, Carey CE, Conley ED, Fakira AK, Farrer LA, Goate A, Gordon S, Henders AK, Hesselbrock V, Kapoor M, Lynskey MT, Madden PA, Moron JA, Rice JP, Saccone NL, Schwab SG, Shand FL, Todorov AA, Wallace L, Wang T, Wray NR, Zhou X, Degenhardt L, Martin NG, Hariri AR, Kranzler HR, Gelernter J, Bierut LJ, Clark DJ, Montgomery GW. Evidence of CNIH3 involvement in opioid dependence. Mol Psychiatry. 2016 May; 21(5):608-14.View Related Profiles.

Farrer, Lindsay
Sherva, Richard

PMID: 26239289; PMCID: PMC4740268; DOI: 10.1038/mp.2015.102;

Wachman EM, Hayes MJ, Sherva R, Brown MS, Davis JM, Farrer LA, Nielsen DA. Variations in opioid receptor genes in neonatal abstinence syndrome. Drug Alcohol Depend. 2015 Oct 1; 155:253-9.View Related Profiles.

Wachman, Elisha
Farrer, Lindsay
Sherva, Richard

PMID: 26233486; PMCID: PMC4581974; DOI: 10.1016/j.drugalcdep.2015.07.001;

Xu K, Kranzler HR, Sherva R, Sartor CE, Almasy L, Koesterer R, Zhao H, Farrer LA, Gelernter J. Genomewide Association Study for Maximum Number of Alcoholic Drinks in European Americans and African Americans. Alcohol Clin Exp Res. 2015 Jul; 39(7):1137-47.View Related Profiles.

Farrer, Lindsay
Sherva, Richard

PMID: 26036284; PMCID: PMC4706077; DOI: 10.1111/acer.12751;

Gross AL, Sherva R, Mukherjee S, Newhouse S, Kauwe JS, Munsie LM, Waterston LB, Bennett DA, Jones RN, Green RC, Crane PK. Calibrating longitudinal cognition in Alzheimer's disease across diverse test batteries and datasets. Neuroepidemiology. 2014; 43(3-4):194-205. PMID: 25402421; PMCID: PMC4297570; DOI: 10.1159/000367970;

Levey DF, Le-Niculescu H, Frank J, Ayalew M, Jain N, Kirlin B, Learman R, Winiger E, Rodd Z, Shekhar A, Schork N, Kiefe F, Wodarz N, Müller-Myhsok B, Dahmen N. Genetic risk prediction and neurobiological understanding of alcoholism. Transl Psychiatry. 2014; 4:e456.View Related Profiles.

Farrer, Lindsay
Sherva, Richard

PMID: 25268260; DOI: 10.1038/tp.2014.74;

Gelernter J, Kranzler HR, Sherva R, Almasy L, Herman AI, Koesterer R, Zhao H, Farrer LA. Genome-wide association study of nicotine dependence in American populations: identification of novel risk loci in both African-Americans and European-Americans. Biol Psychiatry. 2015 Mar 1; 77(5):493-503.View Related Profiles.

Farrer, Lindsay
Sherva, Richard

PMID: 25555482; PMCID: PMC4386684; DOI: 10.1016/j.biopsych.2014.08.025;

Repunte-Canonigo V, Herman MA, Kawamura T, Kranzler HR, Sherva R, Gelernter J, Farrer LA, Roberto M, Sanna PP. Nf1 regulates alcohol dependence-associated excessive drinking and gamma-aminobutyric acid release in the central amygdala in mice and is associated with alcohol dependence in humans. Biol Psychiatry. 2015 May 15; 77(10):870-9.View Related Profiles.

Farrer, Lindsay
Sherva, Richard

PMID: 25483400; PMCID: PMC4428692; DOI: 10.1016/j.biopsych.2014.07.031;

Levey DF, Le-Niculescu H, Frank J, Ayalew M, Jain N, Kirlin B, Learman R, Winiger E, Rodd Z, Shekhar A, Schork N, Kiefer F, Kiefe F, Wodarz N, Müller-Myhsok B, Dahmen N, Nöthen M, Sherva R, Farrer L, Smith AH, Kranzler HR, Rietschel M, Gelernter J, Niculescu AB. Genetic risk prediction and neurobiological understanding of alcoholism. Transl Psychiatry. 2014; 4:e391.View Related Profiles.

Farrer, Lindsay
Sherva, Richard

PMID: 24844177; PMCID: PMC4035721; DOI: 10.1038/tp.2014.29;

Farrer LA, Sherva R, Merkel PA, Siminovitch KA. Reply: To PMID 23740775. Arthritis Rheumatol. 2014 May; 66(5):1401.View Related Profiles.

Farrer, Lindsay
Sherva, Richard

PMID: 24469994; DOI: 10.1002/art.38366;

Gelernter J, Kranzler HR, Sherva R, Almasy L, Koesterer R, Smith AH, Anton R, Preuss UW, Ridinger M, Rujescu D, Wodarz N, Zill P, Zhao H, Farrer LA. Genome-wide association study of alcohol dependence:significant findings in African- and European-Americans including novel risk loci. Mol Psychiatry. 2014 Jan; 19(1):41-9.View Related Profiles.

Farrer, Lindsay
Sherva, Richard

PMID: 24166409; PMCID: PMC4165335; DOI: 10.1038/mp.2013.145;

Gelernter J, Kranzler HR, Sherva R, Koesterer R, Almasy L, Zhao H, Farrer LA. Genome-wide association study of opioid dependence: multiple associations mapped to calcium and potassium pathways. Biol Psychiatry. 2014 Jul 1; 76(1):66-74.View Related Profiles.

Farrer, Lindsay
Sherva, Richard

PMID: 24143882; PMCID: PMC3992201; DOI: 10.1016/j.biopsych.2013.08.034;

Xie G, Roshandel D, Sherva R, Monach PA, Lu EY, Kung T, Carrington K, Zhang SS, Pulit SL, Ripke S, Carette S, Dellaripa PF, Edberg JC, Hoffman GS, Khalidi N, Langford CA, Mahr AD, St Clair EW, Seo P, Specks U, Spiera RF, Stone JH, Ytterberg SR, Raychaudhuri S, de Bakker PI, Farrer LA, Amos CI, Merkel PA, Siminovitch KA. Association of granulomatosis with polyangiitis (Wegener's) with HLA-DPB1*04 and SEMA6A gene variants: evidence from genome-wide analysis. Arthritis Rheum. 2013 Sep; 65(9):2457-68.View Related Profiles.

Farrer, Lindsay
Monach, Paul
Merkel, Peter
Sherva, Richard

PMID: 23740775; PMCID: PMC4471994; DOI: 10.1002/art.38036;

Gelernter J, Sherva R, Koesterer R, Almasy L, Zhao H, Kranzler HR, Farrer L. Genome-wide association study of cocaine dependence and related traits: FAM53B identified as a risk gene. Mol Psychiatry. 2014 Jun; 19(6):717-23.View Related Profiles.

Farrer, Lindsay
Sherva, Richard

PMID: 23958962; PMCID: PMC3865158; DOI: 10.1038/mp.2013.99;

Sherva R, Tripodis Y, Bennett DA, Chibnik LB, Crane PK, de Jager PL, Farrer LA, Saykin AJ, Shulman JM, Naj A, Green RC. Genome-wide association study of the rate of cognitive decline in Alzheimer's disease. Alzheimers Dement. 2014 Jan; 10(1):45-52.View Related Profiles.

Jun, Gyungah
Farrer, Lindsay
Chibnik, Lori
Sherva, Richard
Tripodis, Yorghos

PMID: 23535033; PMCID: PMC3760995; DOI: 10.1016/j.jalz.2013.01.008;

Chung SA, Xie G, Roshandel D, Sherva R, Edberg JC, Kravitz M, Dellaripa PF, Hoffman GS, Mahr AD, Seo P, Specks U, Spiera RF, St Clair EW, Stone JH, Plenge RM, Siminovitch KA, Merkel PA, Monach PA. Meta-analysis of genetic polymorphisms in granulomatosis with polyangiitis (Wegener's) reveals shared susceptibility loci with rheumatoid arthritis. Arthritis Rheum. 2012 Oct; 64(10):3463-71.View Related Profiles.

Monach, Paul
Merkel, Peter
Sherva, Richard

PMID: 22508400; PMCID: PMC3425721; DOI: 10.1002/art.34496;

Chen J, Brunzell DH, Jackson K, van der Vaart A, Ma JZ, Payne TJ, Sherva R, Farrer LA, Gejman P, Levinson DF, Holmans P, Aggen SH, Damaj I, Kuo PH, Webb BT, Anton R, Kranzler HR, Gelernter J, Li MD, Kendler KS, Chen X. ACSL6 is associated with the number of cigarettes smoked and its expression is altered by chronic nicotine exposure. PLoS One. 2011; 6(12):e28790.View Related Profiles.

Farrer, Lindsay
Sherva, Richard

PMID: 22205969; PMCID: PMC3243669; DOI: 10.1371/journal.pone.0028790;

Sherva R, Farrer LA. Power and pitfalls of the genome-wide association study approach to identify genes for Alzheimer's disease. Curr Psychiatry Rep. 2011 Apr; 13(2):138-46.View Related Profiles.

Farrer, Lindsay
Sherva, Richard

PMID: 21312009; PMCID: PMC3154249; DOI: 10.1007/s11920-011-0184-4;

Farrell JJ, Sherva RM, Chen ZY, Luo HY, Chu BF, Ha SY, Li CK, Lee AC, Li RC, Li CK, Yuen HL, So JC, Ma ES, Chan LC, Chan V, Sebastiani P, Farrer LA, Baldwin CT, Steinberg MH, Chui DH. A 3-bp deletion in the HBS1L-MYB intergenic region on chromosome 6q23 is associated with HbF expression. Blood. 2011 May 5; 117(18):4935-45.View Related Profiles.

Baldwin, Clinton
Chui, David
Luo, Hong
Farrer, Lindsay
Steinberg, Martin
Sebastiani, Paola
Sherva, Richard

PMID: 21385855; PMCID: PMC3100700; DOI: 10.1182/blood-2010-11-317081;

Sherva R, Baldwin CT, Inzelberg R, Vardarajan B, Cupples LA, Lunetta K, Bowirrat A, Naj A, Pericak-Vance M, Friedland RP, Farrer LA. Identification of novel candidate genes for Alzheimer's disease by autozygosity mapping using genome wide SNP data. J Alzheimers Dis. 2011; 23(2):349-59.View Related Profiles.

Baldwin, Clinton
Lunetta, Kathryn
Cupples, L
Farrer, Lindsay
Sherva, Richard

PMID: 21098978; PMCID: PMC3819807; DOI: 10.3233/JAD-2010-100714;

Sherva R, Ford CE, Eckfeldt JH, Davis BR, Boerwinkle E, Arnett DK. Pharmacogenetic effect of the stromelysin (MMP3) polymorphism on stroke risk in relation to antihypertensive treatment: the genetics of hypertension associated treatment study. Stroke. 2011 Feb; 42(2):330-5. PMID: 21183746; PMCID: PMC3859235; DOI: 10.1161/STROKEAHA.110.593798;

Love-Gregory L, Sherva R, Schappe T, Qi JS, McCrea J, Klein S, Connelly MA, Abumrad NA. Common CD36 SNPs reduce protein expression and may contribute to a protective atherogenic profile. Hum Mol Genet. 2011 Jan 1; 20(1):193-201. PMID: 20935172; PMCID: PMC3000679; DOI: 10.1093/hmg/ddq449;

Saccone NL, Culverhouse RC, Schwantes-An TH, Cannon DS, Chen X, Cichon S, Giegling I, Han S, Han Y, Keskitalo-Vuokko K, Kong X, Landi MT, Ma JZ, Short SE, Stephens SH, Stevens VL, Sun L, Wang Y, Wenzlaff AS, Aggen SH, Breslau N, Broderick P, Chatterjee N, Chen J, Heath AC, Heliövaara M, Hoft NR, Hunter DJ, Jensen MK, Martin NG, Montgomery GW, Niu T, Payne TJ, Peltonen L, Pergadia ML, Rice JP, Sherva R, Spitz MR, Sun J, Wang JC, Weiss RB, Wheeler W, Witt SH, Yang BZ, Caporaso NE, Ehringer MA, Eisen T, Gapstur SM, Gelernter J, Houlston R, Kaprio J, Kendler KS, Kraft P, Leppert MF, Li MD, Madden PA, Nöthen MM, Pillai S, Rietschel M, Rujescu D, Schwartz A, Amos CI, Bierut LJ. Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD. PLoS Genet. 2010 Aug; 6(8). PMID: 20700436; PMCID: PMC2916847; DOI: 10.1371/journal.pgen.1001053;

Sherva R, Kranzler HR, Yu Y, Logue MW, Poling J, Arias AJ, Anton RF, Oslin D, Farrer LA, Gelernter J. Variation in nicotinic acetylcholine receptor genes is associated with multiple substance dependence phenotypes. Neuropsychopharmacology. 2010 Aug; 35(9):1921-31.View Related Profiles.

Farrer, Lindsay
Logue, Mark
Sherva, Richard

PMID: 20485328; PMCID: PMC3055642; DOI: 10.1038/npp.2010.64;

Sherva R, Sripichai O, Abel K, Ma Q, Whitacre J, Angkachatchai V, Makarasara W, Winichagoon P, Svasti S, Fucharoen S, Braun A, Farrer LA. Genetic modifiers of Hb E/beta0 thalassemia identified by a two-stage genome-wide association study. BMC Med Genet. 2010; 11:51.View Related Profiles.

Farrer, Lindsay
Sherva, Richard

PMID: 20353593; PMCID: PMC2853425; DOI: 10.1186/1471-2350-11-51;

Solovieff N, Milton JN, Hartley SW, Sherva R, Sebastiani P, Dworkis DA, Klings ES, Farrer LA, Garrett ME, Ashley-Koch A, Telen MJ, Fucharoen S, Ha SY, Li CK, Chui DH, Baldwin CT, Steinberg MH. Fetal hemoglobin in sickle cell anemia: genome-wide association studies suggest a regulatory region in the 5' olfactory receptor gene cluster. Blood. 2010 Mar 4; 115(9):1815-22.View Related Profiles.

Baldwin, Clinton
Chui, David
Klings, Elizabeth
Hicks, Jacqueline
Farrer, Lindsay
Steinberg, Martin
Sebastiani, Paola
Sherva, Richard

PMID: 20018918; PMCID: PMC2832816; DOI: 10.1182/blood-2009-08-239517;

Sherva R, Rice JP, Neuman RJ, Rochberg N, Saccone NL, Bierut LJ. Associations and interactions between SNPs in the alcohol metabolizing genes and alcoholism phenotypes in European Americans. Alcohol Clin Exp Res. 2009 May; 33(5):848-57. PMID: 19298322; PMCID: PMC2892966; DOI: 10.1111/j.1530-0277.2009.00904.x;

Sherva R, Wilhelmsen K, Pomerleau CS, Chasse SA, Rice JP, Snedecor SM, Bierut LJ, Neuman RJ, Pomerleau OF. Association of a single nucleotide polymorphism in neuronal acetylcholine receptor subunit alpha 5 (CHRNA5) with smoking status and with 'pleasurable buzz' during early experimentation with smoking. Addiction. 2008 Sep; 103(9):1544-52. PMID: 18783506; PMCID: PMC2582398; DOI: 10.1111/j.1360-0443.2008.02279.x;

Barroso I, Luan J, Wheeler E, Whittaker P, Wasson J, Zeggini E, Weedon MN, Hunt S, Venkatesh R, Frayling TM, Delgado M, Neuman RJ, Zhao J, Sherva R, Glaser B, Walker M, Hitman G, McCarthy MI, Hattersley AT, Permutt MA, Wareham NJ, Deloukas P. Population-specific risk of type 2 diabetes conferred by HNF4A P2 promoter variants: a lesson for replication studies. Diabetes. 2008 Nov; 57(11):3161-5. PMID: 18728231; PMCID: PMC2570416; DOI: 10.2337/db08-0719;

Sherva R, Miller MB, Pankow JS, Hunt SC, Boerwinkle E, Mosley TH, Weder AB, Curb JD, Luke A, Morrison AC, Fornage M, Arnett DK. A whole-genome scan for stroke or myocardial infarction in family blood pressure program families. Stroke. 2008 Apr; 39(4):1115-20. PMID: 18323513; DOI: 10.1161/STROKEAHA.107.490433;

Love-Gregory L, Sherva R, Sun L, Wasson J, Schappe T, Doria A, Rao DC, Hunt SC, Klein S, Neuman RJ, Permutt MA, Abumrad NA. Variants in the CD36 gene associate with the metabolic syndrome and high-density lipoprotein cholesterol. Hum Mol Genet. 2008 Jun 1; 17(11):1695-704. PMID: 18305138; PMCID: PMC2655228; DOI: 10.1093/hmg/ddn060;

Sherva R, Sun L, Biernacka J, Neuman R. No evidence for multiple loci affecting rheumatoid arthritis risk on chromosome 6p21. BMC Proc. 2007; 1 Suppl 1:S42. PMID: 18466541; PMCID: PMC2367585; DOI: 10.1186/1753-6561-1-s1-s42;

Sherva R, Yue P, Schonfeld G, Neuman RJ. Evidence for a quantitative trait locus affecting low levels of apolipoprotein B and low density lipoprotein on chromosome 10 in Caucasian families. J Lipid Res. 2007 Dec; 48(12):2632-9. PMID: 17890784

Sandhu MS, Weedon MN, Fawcett KA, Wasson J, Debenham SL, Daly A, Lango H, Frayling TM, Neumann RJ, Sherva R, Blech I, Pharoah PD, Palmer CN, Kimber C, Tavendale R, Morris AD, McCarthy MI, Walker M, Hitman G, Glaser B, Permutt MA, Hattersley AT, Wareham NJ, Barroso I. Common variants in WFS1 confer risk of type 2 diabetes. Nat Genet. 2007 Aug; 39(8):951-3. PMID: 17603484; PMCID: PMC2672152; DOI: 10.1038/ng2067;

Sherva R, Miller MB, Lynch AI, Devereux RB, Rao DC, Oberman A, Hopkins PN, Kitzman DW, Atwood LD, Arnett DK. A whole genome scan for pulse pressure/stroke volume ratio in African Americans: the HyperGEN study. Am J Hypertens. 2007 Apr; 20(4):398-402. PMID: 17386346; PMCID: PMC1997287; DOI: 10.1016/j.amjhyper.2006.10.001;

Yang Q, Biernacka JM, Chen MH, Houwing-Duistermaat JJ, Bergemann TL, Basu S, Fan R, Liu L, Bourgey M, Clerget-Darpoux F, Lin WY, Elston RC, Cupples LA, Apprey V, Cui J, Dupuis J, Ionita-Laza I, Li R, Lou X, Perdry H, Sherva R, Shugart YY, Suarez B, Wang H, Wormald H, Xing G, Xing C. Using linkage and association to identify and model genetic effects: summary of GAW15 Group 4. Genet Epidemiol. 2007; 31 Suppl 1:S34-42.View Related Profiles.

Dupuis, Josee
Cupples, L
Chen, Ming-Huei
Yang, Qiong
Sherva, Richard

PMID: 18046758

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 80 publications over 18 distinct years, with a maximum of 9 publications in 2023

Bar chart showing 80 publications over 18 distinct years, with a maximum of 9 publications in 2023

Year	Publications
2007	5
2008	4
2009	2
2010	5
2011	4
2012	1
2013	5
2014	6
2015	5
2016	5
2017	8
2018	4
2019	1
2020	8
2021	2
2022	3
2023	9
2024	3

In addition to these self-described keywords below, a list of MeSH based concepts is available here.

genetic epidemiology

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