Richard Sherva, PhD
Assistant Professor
Boston University Chobanian & Avedisian School of Medicine
Medicine
Biomedical Genetics

PhD, University of Minnesota
MPH, University of Minnesota
BA, Gustavus Adolphus College



My primary interest is in exploring the genetic epidemiology of complex disease using linkage and association methods. I’ve worked on cardiovascular phenotypes including hypertension, metabolic syndrome, and stroke, as well as psychiatric diseases including addiction and ADHD, with a focus on gene x (gene, environment, drug treatment) interactions. My future work will likely involve pharmacogenetics and personalized medicine, with specific focus on Alzheimer’s disease.

Member
Boston University
Evans Center for Interdisciplinary Biomedical Research


Member
Boston University
Genome Science Institute


Graduate Medical Sciences Educator and Mentor (Primary Mentor of Graduate Students)
Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences




Genetic Studies of Alzheimer's Disease in Jewish and Arab Populations
09/01/2023 - 08/31/2028 (Multi-PI)
PI: Richard Sherva, PhD
NIH/National Institute on Aging
5U01AG081230-03

Personnel Agreement for Research Services of Richard Sherva
07/01/2023 - 06/30/2026 (PI)
VA Boston Healthcare System


Exploring mechanisms driving microbe-induced AD risk using next generation sequence data
09/30/2021 - 05/31/2026 (PI)
NIH/National Institute on Aging
5R01AG076002-05

Single Cell Analysis for AMD
09/01/2021 - 09/30/2023 (Subcontract PI)
State University of New York at Buffalo Genentech, Inc


Personnel Agreement for Research Services of Richard Sherva
08/01/2018 - 06/30/2022 (PI)
VA Boston Healthcare System


Genetic Architecture of Memory and Executive Functioning in Alzheimer's Disease
09/01/2014 - 05/31/2019 (Subcontract PI)
University of Washington NIH NIA
5R01AG042437-04

Genetics of Rate of Cognitive Decline in a Clinical Trial of AD
11/01/2011 - 10/31/2013 (PI)
Alzheimer's Association




Title


Yr Title Project-Sub Proj Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. Kurniansyah N, Tasaki S, Rehman H, Zhu C, Farrell J, Sherva R, Hauger R, Merritt VC, Panizzon M, Zhang R, Gaziano JM, Gim J, Lee K, Lee DY, Nho K, Vialle RA, Mukherjee S, Trittschuh EH, Lee AJ, Brickman AM, Cruchaga C, Risacher S, Greve DN, Crane P, Martin E, Bush W, Mayeux R, Haines JL, Pericak-Vance MA, Logue M, Bennett DA, Barnes LL, Saykin A, Hohman T, Wang LS, Schellenberg GC, Ang TFA, Au R, Mez J, Lunetta KL, Zhang X, Farrer LA. A multi-ancestry polygenic risk score for Alzheimer disease is associated with cognitive decline, hippocampal atrophy and neuropathological hallmarks in diverse populations. medRxiv. 2025 Sep 27.View Related Profiles. PMID: 41040715; PMCID: PMC12486013; DOI: 10.1101/2025.09.24.25336555;
     
  2. Kang M, Ang TFA, Devine SA, Sherva R, Mukherjee S, Trittschuh EH, Scollard P, Lee M, Choi SE, Klinedinst B, Nakano C, Dumitrescu LC, Hohman TJ, Cuccaro ML, Saykin AJ, Kukull WA, Bennett DA, Wang LS, Mayeux RP, Haines JL, Pericak-Vance MA, Schellenberg GD, Crane PK, Au R, Lunetta KL, Mez J, Farrer LA. Genome-wide pleiotropy analysis of longitudinal blood pressure and harmonized cognitive performance measures. Alzheimers Dement. 2025 Sep; 21(9):e70681.View Related Profiles. PMID: 40951946; PMCID: PMC12434708; DOI: 10.1002/alz.70681;
     
  3. Sherva R, Zhu C, Zhang R, Mez J, Hauger R, Merritt VC, Panizzon M, Gaziano JM, Catanzaro V, Schellenberg GD, Pericak-Vance M, Haines JL, Wang LS, Mayeux R, Farrer LA, Logue MW. Genome-wide association studies of Alzheimer's disease and related disorders stratified by sex, onset age, and Apolipoprotein E genotype reveal novel risk loci in African Americans. Alzheimers Res Ther. 2025 Jul 24; 17(1):171.View Related Profiles. PMID: 40708016; PMCID: PMC12288278; DOI: 10.1186/s13195-025-01782-y;
     
  4. Rajabli F, Benchek P, Tosto G, Kushch N, Sha J, Bazemore K, Zhu C, Lee WP, Haut J, Hamilton-Nelson KL, Wheeler NR, Zhao Y, Farrell JJ, Grunin MA, Leung YY, Kuksa PP, Li D, da Fonseca EL, Mez JB, Palmer EL, Pillai J, Sherva RM, Song YE, Zhang X, Ikeuchi T, Iqbal T, Pathak O, Valladares O, Reyes-Dumeyer D, Kuzma AB, Abner E, Adams LD, Adams PM, Aguirre A, Albert MS, Albin RL, Allen M, Alvarez L, Apostolova LG, Arnold SE, Asthana S, Atwood CS, Auerbach S, Ayres G, Baldwin CT, Barber RC, Barnes LL, Barral S, Beach TG, Becker JT, Beecham GW, Beekly D, Benitez BA, Bennett D, Bertelson J, Bird TD, Blacker D, Boeve BF, Bowen JD, Boxer A, Brewer J, Burke JR, Burns JM, Buxbaum JD, Cairns NJ, Cantwell LB, Cao C, Carlson CS, Carlsson CM, Carney RM, Carrasquillo MM, Chasse S, Chesselet MF, Chin NA, Chui HC, Chung J, Craft S, Crane PK, Cribbs DH, Crocco EA, Cruchaga C, Cuccaro ML, Cullum M, Darby E, Davis B, De Jager PL, DeCarli C, DeToledo J, Dick M, Dickson DW, Dombroski BA, Doody RS, Duara R, Ertekin-Taner N, Evans DA, Faber KM, Fairchild TJ, Fallon KB, Fardo DW, Farlow MR, Fernandez-Hernandez V, Ferris S, Friedland RP, Foroud TM, Frosch MP, Fulton-Howard B, Galasko DR, Gamboa A, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Go RCP, Goate AM, Grabowski TJ, Graff-Radford NR, Green RC, Growdon JH, Hakonarson H, Hall J, Hamilton RL, Harari O, Hardy J, Harrell LE, Head E, Henderson VW, Hernandez M, Hohman T, Honig LS, Huebinger RM, Huentelman MJ, Hulette CM, Hyman BT, Hynan LS, Ibanez L, Jarvik GP, Jayadev S, Jin LW, Johnson K, Johnson L, Kamboh MI, Karydas AM, Katz MJ, Kauwe JS, Kaye JA, Keene CD, Khaleeq A, Kikuchi M, Kim R, Knebl J, Kowall NW, Kramer JH, Kukull WA, LaFerla FM, Lah JJ, Larson EB, Lerner A, Leverenz JB, Levey AI, Lieberman AP, Lipton RB, Logue M, Lopez OL, Lunetta KL, Lyketsos CG, Mains D, Margaret FE, Marson DC, Martin ER, Martiniuk F, Mash DC, Masliah E, Massman P, Masurkar A, McCormick WC, McCurry SM, McDavid AN, McDonough S, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Montine TJ, Monuki ES, Morris JC, Mukherjee S, Myers AJ, Nguyen T, Obisesan T, O'Bryant S, Olichney JM, Ory M, Palmer R, Parisi JE, Paulson HL, Pavlik V, Paydarfar D, Perez V, Peskind E, Petersen RC, Petrovitch H, Pierce A, Polk M, Poon WW, Potter H, Qu L, Quiceno M, Quinn JF, Raj A, Raskind M, Reiman EM, Reisberg B, Reisch JS, Ringman JM, Roberson ED, Rodriguear M, Rogaeva E, Rosen HJ, Rosenberg RN, Royall DR, Sabbagh M, Sadovnick AD, Sager MA, Sano M, Saykin AJ, Schneider JA, Schneider LS, Seeley WW, Slifer SH, Small S, Smith AG, Smith JP, Sonnen JA, Spina S, George-Hyslop PS, Starks TD, Stern RA, Stevens AB, Strittmatter SM, Sultzer D, Swerdlow RH, Tanzi RE, Tilson JL, Trojanowski JQ, Troncoso JC, Tsolaki M, Tsuang DW, Van Deerlin VM, van Eldik LJ, Vance JM, Vardarajan BN, Vassar R, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Whitehead PL, Wijsman EM, Wilhelmsen KC, Williams B, Williamson J, Wilms H, Wingo TS, Wisniewski T, Woltjer RL, Woon M, Wright CB, Wu CK, Younkin SG, Yu CE, Yu L, Zhu X, Kunkle BW, Bush WS, Miyashita A, Byrd GS, Wang LS, Farrer LA, Haines JL, Mayeux R, Pericak-Vance MA, Schellenberg GD, Jun GR, Reitz C, Naj AC. Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies known and novel cross-population and ancestry-specific associations as novel risk loci for Alzheimer's disease. Genome Biol. 2025 Jul 17; 26(1):210.View Related Profiles. PMID: 40676597; PMCID: PMC12273372; DOI: 10.1186/s13059-025-03564-z;
     
  5. Nicolas A, Sherva R, Grenier-Boley B, Kim Y, Kikuchi M, Timsina J, de Rojas I, Dalmasso MC, Zhou X, Le Guen Y, Arboleda-Bustos CE, Camargos Bicalho MA, Guerchet M, van der Lee S, Goss M, Castillo A, Bellenguez C, Küçükali F, Satizabal CL, Fongang B, Yang Q, Peters O, Schneider A, Dichgans M, Rujescu D, Scherbaum N, Deckert J, Riedel-Heller S, Hausner L, Molina-Porcel L, Düzel E, Grimmer T, Wiltfang J, Heilmann-Heimbach S, Moebus S, Tegos T, Scarmeas N, Dols-Icardo O, Moreno F, Pérez-Tur J, Bullido MJ, Pastor P, Sánchez-Valle R, Álvarez V, Cao H, Ip NY, Fu AKY, Ip FCF, Olivar N, Muchnik C, Cuesta C, Campanelli L, Solis P, Politis DG, Kochen S, Brusco LI, Boada M, García-González P, Puerta R, Mir P, Real LM, Piñol-Ripoll G, García-Alberca JM, Royo JL, Rodriguez-Rodriguez E, Soininen H, Heikkinen S, de Mendonça A, Mehrabian S, Traykov L, Hort J, Vyhnalek M, Rasmussen KL, Thomassen JQ, Pijnenburg YAL, Holstege H, van Swieten JC, Seelaar H, Claassen JAHR, Jansen WJ, Ramakers I, Verhey F, van der Lugt A, Scheltens P, Ortega-Rojas J, Concha Mera AG, Mahecha MF, Pardo R, Arboleda G, Bahrami S, Fominykh V, Selbæk G, Graff C, Papenberg G, Giedraitis V, Boland A, Deleuze JF, de Marco LA, de Moraes EN, de Mattos Viana B, Túlio Gualberto Cintra M, Juarez-Cedillo T, Griswold AJ, Forund T, Haines J, Farrer L, DeStefano A, Wijsman E, Mayeux R, Pericak-Vance M, Kunkle B, Goate A, Schellenberg GD, Vardarajan B, Wang LS, Leung YY, Dalgard CL, Nicolas G, Wallon D, Dufouil C, Pasquier F, Hanon O, Debette S, Grünblatt E, Popp J, Angel B, Gloger S, Chacon MV, Aranguiz R, Orellana P, Slachevsky A, Gonzalez-Billault C, Albala C, Fuentes P, Sachdev P, Mather KA, Hauger RL, Merritt V, Panizzon M, Zhang R, Gaziano JM, Ghidoni R, Galimberti D, Arosio B, Mecocci P, Solfrizzi V, Parnetti L, Squassina A, Tremolizzo L, Borroni B, Nacmias B, Caffarra P, Seripa D, Rainero I, Daniele A, Piras F, Leonard HL, Yokoyama JS, Nalls MA, Miyashita A, Hara N, Ozaki K, Niida S, Williams J, Masullo C, Amouyel P, Preux PM, Mbelesso P, Bandzouzi B, Saykin A, Jessen F, Kehoe PG, Van Duijn C, Ben Salem N, Frikke-Schmidt R, Cherni L, Greicius MD, Tsolaki M, Sánchez-Juan P, Romano Silva MA, Porter T, Laws SM, Sleegers K, Ingelsson M, Dartigues JF, Seshadri S, Rossi G, Morelli L, Hiltunen M, Sims R, van der Flier W, Andreassen OA, Arboleda H, Cruchaga C, Escott-Price V, Ruiz A, Lee KH, Ikeuchi T, Ramirez A, Gim J, Logue M, Lambert JC. Transferability of European-derived Alzheimer's disease polygenic risk scores across multiancestry populations. Nat Genet. 2025 Jul; 57(7):1598-1610.View Related Profiles. PMID: 40533518; PMCID: PMC12283339; DOI: 10.1038/s41588-025-02227-w;
     
  6. Han X, Zhang Y, Petrosky JN, Bald S, Sherva RM, Labadorf A, Cherry JD, Chung J, Farrell K, Abdolmohammadi B, Durape S, Martin BM, Palmisano JN, Farrell JJ, Alvarez VE, Huber BR, Dwyer B, Daneshvar DH, Dams-O'Connor K, Jun GR, Lunetta KL, Goldstein LE, Katz DI, Cantu RC, Shenton ME, Cummings JL, Reiman EM, Stern RA, Alosco ML, Tripodis Y, Farrer LA, Stein TD, Crary JF, McKee AC, Mez J. A structural haplotype in the 17q21.31 MAPT region is associated with increased risk for chronic traumatic encephalopathy endophenotypes. Cell Rep Med. 2025 May 20; 6(5):102084.View Related Profiles. PMID: 40239644; PMCID: PMC12147854; DOI: 10.1016/j.xcrm.2025.102084;
     
  7. Pierce ME, Logue M, Sherva R, Miller M, Huber BR, Milberg W, Hayes JP. Association of Alzheimer's disease genetic risk with age-dependent changes in plasma amyloid-ß42:40 in Veterans. J Alzheimers Dis. 2025 Apr; 104(4):1006-1012.View Related Profiles. PMID: 40084666; DOI: 10.1177/13872877251321183;
     
  8. Kang M, Ang TFA, Devine SA, Sherva R, Mukherjee S, Trittschuh EH, Gibbons LE, Scollard P, Lee M, Choi SE, Klinedinst B, Nakano C, Dumitrescu LC, Hohman TJ, Cuccaro ML, Saykin AJ, Kukull WA, Bennett DA, Wang LS, Mayeux RP, Haines JL, Pericak-Vance MA, Schellenberg GD, Crane PK, Au R, Lunetta KL, Mez J, Farrer LA. Genome-wide pleiotropy analysis of longitudinal blood pressure and harmonized cognitive performance measures. medRxiv. 2025 Feb 13.View Related Profiles. PMID: 39990565; PMCID: PMC11844603; DOI: 10.1101/2025.02.11.25322014;
     
  9. Merritt VC, Zhang R, Sherva R, Ly MT, Marra D, Panizzon MS, Tsuang DW, Hauger RL, Logue MW. Curation and validation of electronic medical record-based dementia diagnoses in the VA Million Veteran Program. J Alzheimers Dis. 2025 Jan; 103(1):180-193.View Related Profiles. PMID: 39692476
     
  10. Belloy ME, Le Guen Y, Stewart I, Williams K, Herz J, Sherva R, Zhang R, Merritt V, Panizzon MS, Hauger RL, Gaziano JM, Logue M, Napolioni V, Greicius MD. Role of the X Chromosome in Alzheimer Disease Genetics. JAMA Neurol. 2024 Oct 01; 81(10):1032-1042.View Related Profiles. PMID: 39250132; PMCID: PMC11385320; DOI: 10.1001/jamaneurol.2024.2843;
     
Showing 10 of 91 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 91 publications over 19 distinct years, with a maximum of 9 publications in 2023

YearPublications
20075
20084
20092
20105
20114
20121
20135
20146
20155
20165
20178
20184
20191
20208
20212
20223
20239
20246
20258

In addition to these self-described keywords below, a list of MeSH based concepts is available here.

genetic epidemiology
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