Irving J. Bigio, PhD
Professor
Boston University School of Engineering
Dept of Biomedical Engineering

PhD, University of Michigan at Ann Arbor
MS, University of Michigan at Ann Arbor



Dr. Irving Bigio has been a professor of Biomedical Engineering, and Electrical & Computer Engineering, at Boston University for the past 22 years. His is primarily interested in using biomedical optics to develop clinical and research applications of optical technologies. His lab was founded in 2001 and focuses on clinical diagnostics based on elastic scattering spectroscopy, on laboratory applications to monitor sub-cellular dynamics in vitro, and novel methods to image neuronal activation patterns in label-free neural tissues. He has mentored numerous graduate and undergraduate students and in 2010 he received a Distinguished Lecturer Award from the Boston University College of Engineering.

Professor
Boston University School of Medicine
Medicine
Gastroenterology


2010 Boston University College of Engineering: Distinguished Lecturer Award
2007 Nobel Prize in Physics: Invited Nominator


A SWALLOWED-CAPSULE OPTICAL SCREENING TOOL FOR HISTOLOGICAL ASSESSMENT OF THE ESOPHAGUS
09/30/2017 - 08/31/2020 (PI)
NIH/National Institute of Biomedical Imaging & Bioengineering
5R01EB025673-02

PERSONNEL AGREEMENT FOR RESEARCH SERVICES OF ELADIO RODRIGUEZ-DIAZ
09/01/2018 - 06/30/2019 (PI)
VA Boston Healthcare System

DEVELOPMENT OF OPTICAL INSTRUMENTS FOR SENSING SKIN DISEASE
08/01/2016 - 08/31/2018 (PI)
DermaSensor, Inc.

PERSONNEL AGREEMENT FOR RESEARCH SERVICES OF ELADIO RODRIGUEZ-DIAZ
07/01/2017 - 06/30/2018 (PI)
VA Boston Healthcare System

TRAINING PROGRAM IN QUANTITATIVE BIOLOGY AND PHYSIOLOGY
07/01/2016 - 06/30/2017 (PI)
NIH/National Institute of General Medical Sciences
4T32GM008764-15

CENTER FOR INNOVATION IN POINT OF CARE TECHNOLOGIES FOR THE FUTURE OF CANCER CARE
07/01/2012 - 06/30/2017 (SP Co-PI of Sub-Project / SP)
PI: Catherine M. Klapperich, PhD
NIH/National Institute of Biomedical Imaging & Bioengineering
5U54EB015403-04

COULTER FOUNDATION TRANSLATIONAL PARTNERS IN BIOMEDICAL ENGINEERING YRS 1-5
04/01/2010 - 06/30/2017 (SP Co-PI of Sub-Project / SP)
PI: John A. White, Ph.D
Wallace H. Coulter Foundation

PREDOCTORAL FELLOWSHIP FOR JOSEPH ANGELO
06/01/2015 - 03/01/2017 (Co-PI)
NIH/National Diabetes & Digestive & Kidney Diseases
5F31DK105839-02

TRAINING PROGRAM IN QUANTITATIVE BIOLOGY AND PHYSIOLOGY
07/01/2012 - 06/30/2016 (PI)
NIH/National Institute of General Medical Sciences
5T32GM008764-14

QUANTITATIVE ONCOLOGIC PET-MR
05/01/2015 - 04/30/2016 (PI)
Massachusetts General Hospital NIH NCI
5R01CA165221-04

Showing 10 of 19 results. Show All Results



Yr Title Project-Sub Proj Pubs
2018 A swallowed-capsule optical screening tool for histological assessment of the esophagus 5R01EB025673-02
2017 A swallowed-capsule optical screening tool for histological assessment of the esophagus 1R01EB025673-01
2016 Training Program in Quantitative Biology andPhysiology 4T32GM008764-15 10
2014 Training Program in Quantitative Biology andPhysiology 5T32GM008764-13 10
2013 Training Program in Quantitative Biology andPhysiology 5T32GM008764-12 10
2012 Training Program in Quantitative Biology and Physiology 2T32GM008764-11A1 10
2010 Instrumentation for optical monitoring of apoptosis in unlabeled cell cultures 5R21EB009543-02 4
2009 Instrumentation for optical monitoring of apoptosis in unlabeled cell cultures 1R21EB009543-01A1 4
2008 Optic Imaging of Fast Neural Activation Patterns in Brain Tissue 5R21EB007943-02 1
2007 Optic Imaging of Fast Neural Activation Patterns in Brain Tissue 1R21EB007943-01 1
Showing 10 of 23 results. Show All Results
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Zhu Y, Fearn T, Chicken DW, Austwick MR, Somasundaram SK, Mosse CA, Clark B, Bigio IJ, Keshtgar MRS, Bown SG. Elastic scattering spectroscopy for early detection of breast cancer: partially supervised Bayesian image classification of scanned sentinel lymph nodes. J Biomed Opt. 2018 Aug; 23(8):1-9. PMID: 30132305.
     
  2. Sharaha U, Rodriguez-Diaz E, Riesenberg K, Bigio IJ, Huleihel M, Salman A. Using Infrared Spectroscopy and Multivariate Analysis to Detect Antibiotics' Resistant Escherichia coli Bacteria. Anal Chem. 2017 Sep 05; 89(17):8782-8790.View Related Profiles. PMID: 28731324.
     
  3. Grillone GA, Wang Z, Krisciunas GP, Tsai AC, Kannabiran VR, Pistey RW, Zhao Q, Rodriguez-Diaz E, A'Amar OM, Bigio IJ. The color of cancer: Margin guidance for oral cancer resection using elastic scattering spectroscopy. Laryngoscope. 2017 Sep; 127 Suppl 4:S1-S9.View Related Profiles. PMID: 28752518.
     
  4. Salman A, Sharaha U, Rodriguez-Diaz E, Shufan E, Riesenberg K, Bigio IJ, Huleihel M. Detection of antibiotic resistant Escherichia Coli bacteria using infrared microscopy and advanced multivariate analysis. Analyst. 2017 Jun 12; 142(12):2136-2144.View Related Profiles. PMID: 28518194.
     
  5. Nguyen J, Hossain SS, Cooke JRN, Ellis JA, Deci MB, Emala CW, Bruce JN, Bigio IJ, Straubinger RM, Joshi S. Flow arrest intra-arterial delivery of small TAT-decorated and neutral micelles to gliomas. J Neurooncol. 2017 May; 133(1):77-85. PMID: 28421460; DOI: 10.1007/s11060-017-2429-5;.
     
  6. Angelo J, Vargas CR, Lee BT, Bigio IJ, Gioux S. Ultrafast optical property map generation using lookup tables. J Biomed Opt. 2016 11 01; 21(11):110501. PMID: 27901550; DOI: 10.1117/1.JBO.21.11.110501;.
     
  7. Ellis JA, Cooke J, Singh-Moon RP, Wang M, Bruce JN, Emala CW, Bigio IJ, Joshi S. Safety, feasibility, and optimization of intra-arterial mitoxantrone delivery to gliomas. J Neurooncol. 2016 Dec; 130(3):449-454. PMID: 27576697.
     
  8. Joshi S, Cooke JR, Chan DK, Ellis JA, Hossain SS, Singh-Moon RP, Wang M, Bigio IJ, Bruce JN, Straubinger RM. Liposome size and charge optimization for intraarterial delivery to gliomas. Drug Deliv Transl Res. 2016 Jun; 6(3):225-33. PMID: 27091339; DOI: 10.1007/s13346-016-0294-y;.
     
  9. Badreddine AH, Jordan T, Bigio IJ. Real-time imaging of action potentials in nerves using changes in birefringence. Biomed Opt Express. 2016 May 1; 7(5):1966-73. PMID: 27231635; DOI: 10.1364/BOE.7.001966;.
     
  10. Nguyen J, Cooke JRN, Ellis JA, Deci M, Emala CW, Bruce JN, Bigio IJ, Straubinger RM, Joshi S. Cationizable lipid micelles as vehicles for intraarterial glioma treatment. J Neurooncol. 2016 May; 128(1):21-28. PMID: 26903015; PMCID: PMC4865417; DOI: 10.1007/s11060-016-2088-y;.
     
Showing 10 of 79 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 77 publications over 25 distinct years, with a maximum of 10 publications in 2011

YearPublications
19801
19811
19822
19841
19851
19891
19931
19951
19962
19975
19992
20001
20044
20064
20077
20082
20093
20104
201110
20124
20148
20152
20165
20174
20181
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Medical application of optics lasers, and spectroscopy
Biophotonics
Nonlinear optics
Applied spectroscopy
Laser physics
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44 Cummington St
Boston MA 02215
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