Precursors of Stroke Incidence and Prognosis
09/09/2023 - 08/31/2028 (Multi-PI)
PI: Hugo J. Aparicio, MD, MPH
NIH/National Institute of Neurological Disorders & Stroke
5R01NS017950-39

Massachusetts Center for Alzheimer and dEmeNtia behaVIoral reSearch In minOrity agiNg (Mass-ENVISION) - Community Liaison and Recruitment Core (CLRC)
09/01/2023 - 06/30/2028 (Subcontract PI)
Massachusetts General Hospital NIH NIA
5P30AG083196-02

Identifying ADRD intervention targets by characterizing neurobiological mechanisms of social isolation, loneliness, and social environment dynamics using novel imaging, molecular markers, and...
09/15/2022 - 05/31/2027 (Subcontract PI)
New York University, dba NYU Grossman School of Medicine NIH NIA
5R01AG079282-03

Novel biomarkers to predict cognitive decline and dementia in persons with cerebrovascular disease
07/01/2020 - 06/30/2025 (PI)
American Academy of Neurology


Precursors of Stroke Incidence and Prognosis
09/09/2023 - 09/10/2023 (Multi-PI)
PI: Hugo J. Aparicio, MD, MPH
NIH/National Institute of Neurological Disorders & Stroke
2R01NS017950-38A1

Blood biomarkers for prediction of vascular cognitive impairment & dementia
07/01/2020 - 06/30/2023 (PI)
Alzheimer's Association

1. Sheehy S, Aparicio HJ, Xu NN, Lioutas VA, Shulman JG, Rosenberg L. Gestational Diabetes and Risk of Stroke Among US Black Women. Stroke. 2025 Jul; 56(7):1779-1785.View Related Profiles.

   Aparicio, Hugo
   Shulman, Julie
   

   PMID: 40308193
2. Salardini A, Himali JJ, Abdullah MS, Chaudhari R, Young V, Zilli EM, McGrath ER, Gonzales MM, Thibault EG, Salinas J, Aparicio HJ, Himali D, Ghosh S, Buckley RF, Satizabal CL, Johnson KA, DeCarli C, Fakhri GE, Vasan RS, Beiser AS, Seshadri S. Elevated serum cortisol associated with early-detected increase of brain amyloid deposition in Alzheimer's disease imaging biomarkers among menopausal women: The Framingham Heart Study. Alzheimers Dement. 2025 Apr; 21(4):e70179.View Related Profiles.

   Beiser, Alexa
   Satizabal, Claudia
   Aparicio, Hugo
   Himali, Jayandra
   Seshadri, Sudha
   

   PMID: 40271551; PMCID: PMC12019305; DOI: 10.1002/alz.70179;
3. Labonte J, Sugarman MA, Pettway E, Zetterberg H, Blennow K, Ashton NJ, Karikari TK, Aparicio HJ, Frank B, Tripodis Y, Martin B, Palmisano JN, Steinberg EG, Simkin I, Farrer LA, Jun GR, Turk KW, Budson AE, O'Connor MK, Au R, Goldstein LE, Stern RA, Stein TD, McKee AC, Qiu WQ, Mez J, Banks SJ, Alosco ML. Sex differences on tau, astrocytic, and neurodegenerative plasma biomarkers. J Alzheimers Dis. 2025 May; 105(2):443-452.View Related Profiles.

   Budson, Andrew
   McKee, Ann
   Frank, Brandon
   Steinberg, Eric
   Jun, Gyungah
   Aparicio, Hugo
   Mez, Jesse
   Palmisano, Joseph
   Turk, Katherine
   Goldstein, Lee
   Farrer, Lindsay
   O'Connor, Maureen
   Alosco, Michael
   Au, Rhoda
   Stern, Robert
   Stein, Thor
   Tripodis, Yorghos
   

   PMID: 40151917
4. Petrie BK, Lau H, Cajiga-Pena FM, Abbas S, Finn B, Dam K, Cervantes-Arslanian AM, Nguyen TN, Aparicio HJ, Greer D, Romero JR. Illicit drug use and cerebral microbleeds in patients with acute ischemic stroke and transient ischemic attack. Int J Stroke. 2025 Mar 11; 17474930251328524.View Related Profiles.

   Cervantes-Arslanian, Anna
   Greer, David
   Aparicio, Hugo
   Romero, Jose
   Nguyen, Thanh
   

   PMID: 40070091; DOI: 10.1177/17474930251328524;
5. Levine DA, Whitney RT, Ye W, Briceño EM, Gross AL, Giordani BJ, Sussman JB, Lazar RM, Howard VJ, Aparicio HJ, Beiser AS, Elkind MSV, Gottesman RF, Koton S, Pendlebury ST, Kollipara AS, Springer MV, Seshadri S, Romero JR, Fitzpatrick AL, Longstreth WT, Hayward RA. Associations Between Stroke Type, Ischemic Stroke Subtypes, and Poststroke Cognitive Trajectories. Stroke. 2025 Apr; 56(4):898-907.View Related Profiles.

   Beiser, Alexa
   Aparicio, Hugo
   Romero, Jose
   Seshadri, Sudha
   

   PMID: 40062407; PMCID: PMC12101623; DOI: 10.1161/STROKEAHA.124.047640;
6. Springer MV, Whitney RT, Ye W, Briceño EM, Gross AL, Aparicio HJ, Beiser AS, Burke JF, Elkind MSV, Ferber RA, Giordani B, Gottesman RF, Hayward RA, Howard VJ, Kollipara AS, Koton S, Lazar RM, Longstreth WT, Pendlebury ST, Sussman JB, Thacker EL, Levine DA. Education Levels and Poststroke Cognitive Trajectories. JAMA Netw Open. 2025 Mar 03; 8(3):e252002.View Related Profiles.

   Beiser, Alexa
   Aparicio, Hugo
   

   PMID: 40136300; PMCID: PMC11947833; DOI: 10.1001/jamanetworkopen.2025.2002;
7. Greenberg SM, Aparicio HJ, Furie KL, Goyal MS, Hinman JD, Kozberg M, Leonard A, Fisher MJ. Vascular Neurology Considerations for Antiamyloid Immunotherapy: A Science Advisory From the American Heart Association. Stroke. 2025 Jan; 56(1):e30-e38. PMID: 39660440
8. van Lent DM, Mesa HG, Short MI, Gonzales MM, Aparicio HJ, Salinas J, Yuan C, Jacques PF, Beiser A, Seshadri S, Jacob ME, Himali JJ. Association between dietary inflammatory index score and incident dementia. Alzheimers Dement. 2025 Jan; 21(1):e14390.View Related Profiles.

   Beiser, Alexa
   Aparicio, Hugo
   Himali, Jayandra
   Seshadri, Sudha
   

   PMID: 39641390; PMCID: PMC11772702; DOI: 10.1002/alz.14390;
9. Pinheiro A, Aparicio H, Lioutas V, Beiser A, Ekenze O, DeCarli C, Seshadri S, Demissie S, Romero JR. Higher burden of cerebral small vessel disease is associated with risk of incident stroke in community dwelling individuals. medRxiv. 2024 Nov 15.View Related Profiles.

   Beiser, Alexa
   Aparicio, Hugo
   Demissie, Serkalem
   Seshadri, Sudha
   

   PMID: 39606408; PMCID: PMC11601694; DOI: 10.1101/2024.11.13.24317296;
10. Yau WW, Scott MR, Petrea RE, Buckley RF, Kojis D, Sperling RA, Chhatwal JP, Maillard P, Aparicio HJ, Romero JR, DeCarli CS, Beiser AS, Seshadri S. Sex-Specific Vulnerabilities to Subclinical Vascular Brain Injury in Early Late-Life: The Framingham Heart Study. Ann Neurol. 2025 Mar; 97(3):460-469.View Related Profiles.

    Beiser, Alexa
    Aparicio, Hugo
    Romero, Jose
    Petrea, Rodica
    Seshadri, Sudha
    

    PMID: 39540324; PMCID: PMC12034097; DOI: 10.1002/ana.27135;

Showing 10 of 95 results. Show More

What might the next century hold for cardiovascular disease prevention and care?

High blood pressure before 35 may triple Black women’s stroke risk

High Blood Pressure Triples Stroke Risk for Black Women Under 35, Study Finds

Stroke risk increased 3-fold by hypertension before age 35 in Black women

Risk for stroke tripled among young Black women with high blood pressure

High Blood Pressure in Young Black Women Sends Stroke Risks Soaring

Black women with high blood pressure before age 35 have triple the risk of a stroke

Hypertension Before 35 Tied to Triple Stroke Risk in Midlife

Black women under 35 with high blood pressure may have triple the risk of stroke, study says

High Blood Pressure in Young Black Women Sends Stroke Risks Soaring

Indigenous populations may have higher stroke risk

Seven BU Latinx Researchers Making a Difference

Race Matters in Stroke Survival, Study Finds

The Severity Of Depressive Symptoms Over Time May Help Predict Stroke Risk

Blood Pressure Trajectories in Early Adulthood Associated with Cerebral Lesions and Brain Structure in Midlife

Low blood pressure linked to increased death risk following stroke

Can Low Blood Pressure Lead to Stroke? Read on to Find Out More

Low Blood Pressure Linked to Increased Death Risk Following Stroke

Seizures Tied to a Doubling of Dementia Risk in Young Survivors

AHA News: Blood Test That Measures Alcohol Use May Predict Risk for Bleeding Strokes

Surviving a Stroke, Caroline's Story

Long-term Decline in Stroke Greater in Older Adults: Study

Longitudinal cohort studies could be a good alternative for early career investigators

2018–2019 Career Development Awards Honor Eight Junior Faculty