Hugo J. Aparicio, MD, MPH
Associate Professor
Boston University Chobanian & Avedisian School of Medicine
Neurology

MD, University of Pennsylvania School of Medicine
MPH, Harvard School of Public Health
BA, Emory University



Dr. Aparicio's research interests include the identification of lifestyle risk factors, biomarkers, neuroimaging markers and genetic influences associated with cerebrovascular diseases. He is particularly interested in the contributions of vascular risk factors to stroke, brain injury and aging, cognitive dysfunction and the development of Alzheimer’s disease and the influence of racial and ethnic disparities on these outcomes.

Investigator
Framingham Heart Study




Massachusetts Center for Alzheimer and dEmeNtia behaVIoral reSearch In minOrity agiNg (Mass-ENVISION) - Community Liaison and Recruitment Core (CLRC)
09/01/2023 - 06/30/2028 (Subcontract PI)
Massachusetts General Hospital NIH NIA
1P30AG083196-01

Identifying ADRD intervention targets by characterizing neurobiological mechanisms of social isolation, loneliness, and social environment dynamics using novel imaging, molecular markers, and...
09/15/2022 - 05/31/2027 (Subcontract PI)
New York University, dba NYU Grossman School of Medicine NIH NIA
5R01AG079282-03

Novel biomarkers to predict cognitive decline and dementia in persons with cerebrovascular disease
07/01/2020 - 06/30/2025 (PI)
American Academy of Neurology


Precursors of Stroke Incidence and Prognosis
09/09/2023 - 09/10/2023 (Multi-PI)
PI: Hugo J. Aparicio, MD, MPH
NIH/National Institute of Neurological Disorders & Stroke
2R01NS017950-38A1

Blood biomarkers for prediction of vascular cognitive impairment & dementia
07/01/2020 - 06/30/2023 (PI)
Alzheimer's Association



DISCOVERY: Administrative Core
09/19/2019 - 08/31/2025 (Subcontract PI)
PI: Hugo J. Aparicio, MD, MPH
Massachusetts General Hospital NIH


Title


Yr Title Project-Sub Proj Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Kelly DM, Pinheiro AA, Koini M, Anderson CD, Aparicio H, Hofer E, Kern D, Blacker D, DeCarli C, Hwang SJ, Viswanathan A, Gonzales MM, Beiser AS, Seshadri S, Schmidt R, Demissie S, Romero JR. Impaired kidney function, cerebral small vessel disease and cognitive disorders: the Framingham Heart Study. Nephrol Dial Transplant. 2024 Oct 30; 39(11):1911-1922.View Related Profiles. PMID: 38565317
     
  2. Springer MV, Chen B, Whitney RT, Briceño EM, Gross AL, Aparicio HJ, Beiser AS, Burke JF, Giordani B, Gottesman RF, Hayward RA, Howard VJ, Koton S, Lazar RM, Sussman JB, Ye W, Levine DA. Age differences in the change in cognition after stroke. J Stroke Cerebrovasc Dis. 2024 Oct 12; 33(12):108087.View Related Profiles. PMID: 39401577
     
  3. Elmore AR, Adhikari N, Hartley AE, Aparicio HJ, Posner DC, Hemani G, Tilling K, Gaunt TR, Wilson PWF, Casas JP, Gaziano JM, Davey Smith G, Paternoster L, Cho K, Peloso GM. Protein Identification for Stroke Progression via Mendelian Randomization in Million Veteran Program and UK Biobank. Stroke. 2024 Aug; 55(8):2045-2054.View Related Profiles. PMID: 39038097; PMCID: PMC11259242; DOI: 10.1161/STROKEAHA.124.047103;
     
  4. Stefanucci L, Moslemi C, Tomé AR, Virtue S, Bidault G, Gleadall NS, Watson LPE, Kwa JE, Burden F, Farrow S, Chen J, Võsa U, Burling K, Walker L, Ord J, Barker P, Warner J, Frary A, Renhstrom K, Ashford SE, Piper J, Biggs G, Erber WN, Hoffman GJ, Schoenmakers N, Erikstrup C, Rieneck K, Dziegiel MH, Ullum H, Azzu V, Vacca M, Aparicio HJ, Hui Q, Cho K, Sun YV, Wilson PW, Bayraktar OA, Vidal-Puig A, Ostrowski SR, Astle WJ, Olsson ML, Storry JR, Pedersen OB, Ouwehand WH, Chatterjee K, Vuckovic D, Frontini M. SMIM1 absence is associated with reduced energy expenditure and excess weight. Med. 2024 Sep 13; 5(9):1083-1095.e6. PMID: 38906141
     
  5. Joynt Maddox KE, Elkind MSV, Aparicio HJ, Commodore-Mensah Y, de Ferranti SD, Dowd WN, Hernandez AF, Khavjou O, Michos ED, Palaniappan L, Penko J, Poudel R, Roger VL, Kazi DS. Forecasting the Burden of Cardiovascular Disease and Stroke in the United States Through 2050-Prevalence of Risk Factors and Disease: A Presidential Advisory From the American Heart Association. Circulation. 2024 Jul 23; 150(4):e65-e88. PMID: 38832505
     
  6. Levine DA, Whitney RT, Ye W, Briceño EM, Gross AL, Giordani BJ, Sussman JB, Lazar RM, Howard VJ, Aparicio HJ, Beiser AS, Elkind MSV, Gottesman RF, Koton S, Pendlebury ST, Kollipara AS, Springer MV, Seshadri S, Romero JR, Fitzpatrick AL, Longstreth WT, Hayward RA. Associations Between Stroke Type, Ischemic Stroke Subtypes, and Post-Stroke Cognitive Trajectories. medRxiv. 2024 May 01.View Related Profiles. PMID: 38903102; PMCID: PMC11188123; DOI: 10.1101/2024.04.29.24306600;
     
  7. DeCarli C, Maillard P, Pase MP, Beiser AS, Kojis D, Satizabal CL, Himali JJ, Aparicio HJ, Fletcher E, Seshadri S. Trends in Intracranial and Cerebral Volumes of Framingham Heart Study Participants Born 1930 to 1970. JAMA Neurol. 2024 May 01; 81(5):471-480.View Related Profiles. PMID: 38526486; PMCID: PMC10964161; DOI: 10.1001/jamaneurol.2024.0469;
     
  8. Elmore A, Adhikari N, Hartley AE, Javier Aparicio H, Posner DC, Hemani G, Tilling K, Gaunt TR, Wilson P, Casas JP, Michael Gaziano J, Smith GD, Paternoster L, Cho K, Peloso GM. Protein identification for stroke progression via Mendelian Randomization in Million Veteran Program and UK Biobank. medRxiv. 2024 Feb 01.View Related Profiles. PMID: 38352469; PMCID: PMC10863017; DOI: 10.1101/2024.01.31.24302111;
     
  9. Pase MP, Himali JJ, Puerta R, Beiser AS, Gonzales MM, Satizabal CL, Yang Q, Aparicio HJ, Kojis DJ, Decarli CS, Lopez OL, Longstreth W, Gudnason V, Mosley TH, Bis JC, Fohner A, Psaty BM, Boada M, García-González P, Valero S, Marquié M, Tracy R, Launer LJ, Ruiz A, Fornage M, Seshadri S. Association of Plasma YKL-40 With MRI, CSF, and Cognitive Markers of Brain Health and Dementia. Neurology. 2024 Feb 27; 102(4):e208075.View Related Profiles. PMID: 38290090; PMCID: PMC11383876; DOI: 10.1212/WNL.0000000000208075;
     
  10. Zhao A, Balcer LJ, Himali JJ, O'Donnell A, Rahimpour Y, DeCarli C, Gonzales MM, Aparicio HJ, Ramos-Cejudo J, Kenney R, Beiser A, Seshadri S, Salinas J. Association of Loneliness with Functional Connectivity MRI, Amyloid-ß PET, and Tau PET Neuroimaging Markers of Vulnerability for Alzheimer's Disease. J Alzheimers Dis. 2024; 99(4):1473-1484.View Related Profiles. PMID: 38820017; PMCID: PMC11191473; DOI: 10.3233/JAD-231425;
     
Showing 10 of 85 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 85 publications over 11 distinct years, with a maximum of 18 publications in 2023

YearPublications
20091
20153
20163
20178
20183
20197
20209
202111
202212
202318
202410

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What might the next century hold for cardiovascular disease prevention and care?

American Heart Association 6/28/2024

High blood pressure before 35 may triple Black women’s stroke risk

New Pittsburgh Courier 6/9/2024

High Blood Pressure Triples Stroke Risk for Black Women Under 35, Study Finds

Milwaukee Courier 2/17/2024

Stroke risk increased 3-fold by hypertension before age 35 in Black women

Contemporary OB/GYN 2/16/2024

Risk for stroke tripled among young Black women with high blood pressure

Healio 2/10/2024

High Blood Pressure in Young Black Women Sends Stroke Risks Soaring

HealthDay 2/1/2024

Black women with high blood pressure before age 35 have triple the risk of a stroke

MedicalNewsToday 2/1/2024

Hypertension Before 35 Tied to Triple Stroke Risk in Midlife

Medscape 2/1/2024

Black women under 35 with high blood pressure may have triple the risk of stroke, study says

NBC News 2/1/2024

High Blood Pressure in Young Black Women Sends Stroke Risks Soaring

US News & World Report 2/1/2024

Indigenous populations may have higher stroke risk

American Heart Association News 2/6/2023

Seven BU Latinx Researchers Making a Difference

BU Today 10/3/2022

Race Matters in Stroke Survival, Study Finds

HealthDay 6/10/2022

The Severity Of Depressive Symptoms Over Time May Help Predict Stroke Risk

Emergency Live 5/29/2022

Blood Pressure Trajectories in Early Adulthood Associated with Cerebral Lesions and Brain Structure in Midlife

Neurology Today 5/5/2022

Low blood pressure linked to increased death risk following stroke

Economic World 11/6/2021

Can Low Blood Pressure Lead to Stroke? Read on to Find Out More

News 18 11/5/2021

Low Blood Pressure Linked to Increased Death Risk Following Stroke

Latestly 11/5/2021

Seizures Tied to a Doubling of Dementia Risk in Young Survivors

Medscape 10/26/2021

AHA News: Blood Test That Measures Alcohol Use May Predict Risk for Bleeding Strokes

Health Day 6/16/2020

Surviving a Stroke, Caroline's Story

WPRI 2/20/2020

Long-term Decline in Stroke Greater in Older Adults: Study

Drug News.in 5/28/2019

Longitudinal cohort studies could be a good alternative for early career investigators

News Medical 3/11/2019

2018–2019 Career Development Awards Honor Eight Junior Faculty

BU Today 9/13/2018

2020-2024 American Academy of Neurology: Career Development Award
2020-2023 Alzheimer's Association: Research Grant to Promote Diversity
2018-2021 Boston University School of Medicine: Aram V. Chobanian Assistant Professor
2015-2021 NIH/NINDS: Loan Repayment Program
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Dementia
Epidemiology
Genetics
Healthcare disparities
Population studies
Stroke
Health Equity
Biomarkers

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72 E. Concord St Robinson (B)
Boston MA 02118
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