David T. Felson, MD, MPH
Boston University Chobanian & Avedisian School of Medicine
Dept of Medicine

MD, Johns Hopkins University
MPH, Boston University School of Public Health
AB, Harvard College

Dr. David Felson's research interests include: understanding how to prevent osteoarthritis and treat osteoarthritis. In osteoarthritis, Dr. Felson’s interests include studying whether treatments for rheumatic diseases are effective and particularly in osteoarthritis, identifying biomechanical risk factors for disease and testing biomechanical treatments and characterizing MRI features of normal knees and knees with pain. He also studies outcome measurement in rheumatic disease and has focused in this work on rheumatoid arthritis trials.

Boston University School of Public Health

Framingham Heart Study

Boston University
Arthritis & Autoimmune Diseases Research Center

Boston University
Evans Center for Interdisciplinary Biomedical Research

Graduate Faculty (Primary Mentor of Grad Students)
Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences

Institutional Career Development
04/15/2020 - 03/31/2025 (PI)
NIH/National Center for Advancing Translational Sciences

The Boston University Clinical and Transitional Science Institute
04/15/2020 - 03/31/2025 (Key Person)
PI: Megan H. Bair-Merritt, MD, MSCE
NIH/National Center for Advancing Translational Sciences

Boston University CCCR
09/11/2019 - 07/31/2024 (PI)
NIH/National Institute of Arthritis & Musculoskeletal & Skin Diseases

FastOA-MIL: Identification of Rapid Progression of PTOA in the Military Health System
10/29/2021 - 10/28/2023 (PI)
Arthritis Foundation

Systemic contribution of age-associated epigenetic mechanisms to osteoarthritis
07/01/2020 - 06/30/2023 (Subcontract PI)
Hebrew SeniorLife NIH NIAMS

Fats, Fiber and Osteoarthritis
08/01/2017 - 05/31/2023 (PI)
NIH/National Institute of Arthritis & Musculoskeletal & Skin Diseases

Multicenter Osteoarthritis Study (MOST) Second Renewal-Boston University
07/01/2015 - 05/31/2023 (PI)
NIH/National Institute on Aging

Uncovering the Genetic Mechanisms Behind Joint-Specific Osteoarthritis
04/01/2018 - 01/31/2023 (Subcontract PI)
President and Fellows of Harvard College NIH NIAMS

FastOA: Predictors of rapid symptom progression after ACL reconstruction
01/01/2021 - 12/31/2022 (Subcontract PI)
Cleveland Clinic Foundation Arthritis Foundation

Rheumatology Training Grant
05/01/2014 - 09/16/2020 (PI)
NIH/National Institute of Arthritis & Musculoskeletal & Skin Diseases

Showing 10 of 49 results. Show All Results


Yr Title Project-Sub Proj Pubs
2022 Administrative Core 5P30AR072571-04-7274
2022 Boston University CCCR 5P30AR072571-04
2021 Boston University CCCR 5P30AR072571-03
2021 Administrative Core 5P30AR072571-03-7274
2021 Institutional Career Development 5KL2TR001411-06 22
2020 Administrative Core 5P30AR072571-02-7274
2020 Boston University CCCR 5P30AR072571-02
2020 Fats, Fiber and Osteoarthritis 5R01AR071950-04 1
2020 Institutional Career Development 2KL2TR001411-05A1 22
2019 Administrative Core 1P30AR072571-01A1-7274
Showing 10 of 161 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. Jafarzadeh SR, Neogi T, White DK, Felson DT. The Relationship of Pain Reduction With Prevention of Knee Replacement Under Dynamic Intervention Strategies. Arthritis Rheumatol. 2022 Oct; 74(10):1668-1675.View Related Profiles. PMID: 35726122; PMCID: PMC9529798; DOI: 10.1002/art.42272;
  2. Liew JW, Peloquin C, Tedeschi SK, Felson DT, Zhang Y, Choi HK, Terkeltaub R, Neogi T. Proton-Pump Inhibitors and Risk of Calcium Pyrophosphate Deposition in a Population-Based Study. Arthritis Care Res (Hoboken). 2022 Dec; 74(12):2059-2065.View Related Profiles. PMID: 35245410; PMCID: PMC9440954; DOI: 10.1002/acr.24876;
  3. Zertuche JP, Rabasa G, Lichtenstein AH, Matthan NR, Nevitt M, Torner J, Lewis CE, Dai Z, Misra D, Felson D. Alkylresorcinol, a biomarker for whole grain intake, and its association with osteoarthritis: the MOST study. Osteoarthritis Cartilage. 2022 Oct; 30(10):1337-1343.View Related Profiles. PMID: 35863678; PMCID: PMC9554937; DOI: 10.1016/j.joca.2022.07.004;
  4. Kim JS, Borges S, Clauw DJ, Conaghan PG, Felson DT, Fleming TR, Glaser R, Hart E, Hochberg M, Kim Y, Kraus VB, Lapteva L, Li X, Majumdar S, McAlindon TE, Mobasheri A, Neogi T, Roemer FW, Rothwell R, Shibuya R, Siegel J, Simon LS, Spindler KP, Nikolov NP. FDA/Arthritis Foundation osteoarthritis drug development workshop recap: Assessment of long-term benefit. Semin Arthritis Rheum. 2022 Oct; 56:152070.View Related Profiles. PMID: 35870222; PMCID: PMC9452453; DOI: 10.1016/j.semarthrit.2022.152070;
  5. Carlesso LC, Jafarzadeh SR, Stokes A, Felson DT, Wang N, Frey-Law L, Lewis CE, Nevitt M, Neogi T. Depressive symptoms and multi-joint pain partially mediate the relationship between obesity and opioid use in people with knee osteoarthritis. Osteoarthritis Cartilage. 2022 Sep; 30(9):1263-1269.View Related Profiles. PMID: 35700904; PMCID: PMC9419857; DOI: 10.1016/j.joca.2022.06.002;
  6. Felson D, Feathers V, Naik C, Solomon DH, Weinblatt ME, Shadick N. Meaning of patient global assessment when joint counts are low in rheumatoid arthritis. RMD Open. 2022 Jun; 8(2). PMID: 35738804; PMCID: PMC9226990; DOI: 10.1136/rmdopen-2022-002346;
  7. Liu M, Huang Y, Zhang H, Aitken D, Nevitt MC, Rockel JS, Pelletier JP, Lewis CE, Torner J, Rampersaud YR, Perruccio AV, Mahomed NN, Furey A, Randell EW, Rahman P, Sun G, Martel-Pelletier J, Kapoor M, Jones G, Felson D, Qi D, Zhai G. Restricting Branched-Chain Amino Acids within a High-Fat Diet Prevents Obesity. Metabolites. 2022 Apr 07; 12(4). PMID: 35448521; PMCID: PMC9030079; DOI: 10.3390/metabo12040334;
  8. Murphy MT, Wang N, Felson DT, Nevitt MC, Lewis CE, Frey-Law L, Guermazi A, Segal NA. Association between hamstring coactivation during isokinetic quadriceps strength testing and knee cartilage worsening over 24 months. Osteoarthritis Cartilage. 2022 Jun; 30(6):823-831.View Related Profiles. PMID: 35307535; PMCID: PMC9450915; DOI: 10.1016/j.joca.2022.03.002;
  9. Gates LS, Perry TA, Golightly YM, Nelson AE, Callahan LF, Felson D, Nevitt M, Jones G, Cooper C, Batt ME, Sanchez-Santos MT, Arden NK. Recreational Physical Activity and Risk of Incident Knee Osteoarthritis: An International Meta-Analysis of Individual Participant-Level Data. Arthritis Rheumatol. 2022 04; 74(4):612-622. PMID: 34730279; PMCID: PMC9450021; DOI: 10.1002/art.42001;
  10. Roemer FW, Felson DT, Stefanik JJ, Rabasa G, Wang N, Crema MD, Neogi T, Nevitt MC, Torner J, Lewis CE, Peloquin C, Guermazi A. Heterogeneity of cartilage damage in Kellgren and Lawrence grade 2 and 3 knees: the MOST study. Osteoarthritis Cartilage. 2022 May; 30(5):714-723.View Related Profiles. PMID: 35202808; PMCID: PMC9433455; DOI: 10.1016/j.joca.2022.02.614;
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