I am a rheumatologist and epidemiologist whose research has focused primarily on risk factors for knee osteoarthritis and gout, pain mechanisms in knee osteoarthritis, as well as methodologic issues of relevance for rheumatic diseases. I have had continuous peer-reviewed foundation and NIH funding since 2003, and have over 300 peer-reviewed publications to date. I am a past chair of the FDA Arthritis Advisory Committee, serve(d) on the boards two international societies: Osteoarthritis Research Society International (OARSI) and Gout, Hyperuricemia, and Crystal-Associated Diseases Network (G-CAN), and on committees for the American College of Rheumatology (ACR) and International Association for the Study Pain (IASP), among others. My work has been recognized with the prestigious 2014 ACR Henry Kunkel Young Investigator Award for outstanding and promising independent contributions to rheumatology research (awarded to no more than one clinical researcher and/or one basic science researcher each year), and the 2022 OARSI Clinical Research Award (in recognition of important contributions to OA research). I have also engaged in developing new classification criteria for a number of rheumatic diseases. In addition to research, clinical work, and teaching, one of my key roles is to mentor trainees and junior faculty in musculoskeletal disease-related research. To that end, I was awarded the 2016 Robert Dawson Evans Research Mentoring Award. I also developed and led the new CTSI Research Career Support Program initiative, PRIME (Pathways to Research Independence and Mentoring Excellence), which aims to support early career mentored researchers to successfully transition to becoming independent researchers.
- Osteoarthritis: epidemiology; risk factors; mechanisms of osteoarthritis-related pain; the role of bone in the pathophysiology of osteoarthritis
- Gout: epidemiology; risk factors and triggers for gout attacks; management of gout; consequences of gout and hyperuricemia
- Classification criteria and outcome measures in rheumatic diseases.
- Novel methodology to address challenging epidemiologic issues
Diversity, Equity, Inclusion and Accessibility
As Chief of Rheumatology, I have launched and supported a number of DEIA-related initiatives, including as examples: monthly Section-wide JEDI (Justice, Equity, Diversity, Inclusion) meeting involving staff, trainees, and faculty at which we address DEI topics of relevance to medicine, academia, work environment, interpersonal interactions, structural/systemic policies, etc.; a standardized and structured fellowship interview process with a DEI lens; programs focused on health equity for our patients.
At the institutional level, I serve/have served on: Women's Leadership Advisory Board, Diversity & Inclusion Advisory Council, BMC's Equity Acceleratory Research Working Group ("WG4")
COVID19-related DEI activities at BUMC:
- I am co-PI with Dr. Megan Bair-Merritt on the 2022 Doris Duke Charitable Foundation COVID-19 Fund to Retain Clinical Scientists to provide support to faculty whose research was disrupted by the adverse effects of the pandemic, compounded by caregiving responsibilities. (https://www.ddcf.org/news--insights/articles/largest-us-collaborative-funding-effort-for-equity-in-biomedicine-awards-$12.1-million-in-grants/)
- In the earliest phase of the COVID-19 pandemic, our patients at BMC were among the most affected people in the city, yet pharmaceutical companies were not bringing their clinical trials to our institution. I worked closely with a multidisciplinary group, the Clinical Trials Office, and BMC leadership to bring one of the first therapeutic trials to BMC to better serve our patients, who are often from backgrounds traditionally excluded from clinical trials. We were among the highest recruiting sites, and we had the most diversity, with >80% speaking a first-language other than English
Boston University School of Public Health
Boston Medical Center
Framingham Heart Study
Arthritis & Autoimmune Diseases Research Center
Evans Center for Interdisciplinary Biomedical Research
Section Chief of Rheumatology
Boston University Chobanian & Avedisian School of Medicine
Boston University Rheumatology Research Training (BURRT) T32 Program
06/01/2022 - 05/31/2027 (PI)NIH/National Institute of Arthritis & Musculoskeletal & Skin Diseases1T32AR080623-01
PRROPS: Pathways of Risk and Resilience for Overlapping Pain and Sensitization
07/15/2021 - 04/30/2026 (Multi-PI)
PI: Tuhina Neogi, MD, PhDNIH/National Institute of Neurological Disorders & Stroke3R01NS121419-02S1
Pain in community-based older African American Adults: The Jackson Heart Study
09/30/2020 - 05/31/2025 (Multi-PI)
PI: Tuhina Neogi, MD, PhDNIH/National Institute on Aging5R01AG066914-03
CAPSITE: Community Assessment of Pain and Sensitization in the Elderly
01/01/2020 - 11/30/2024 (Multi-PI)
PI: Tuhina Neogi, MD, PhDNIH/National Institute on Aging5R01AG066010-03
The impact of axial spondyloarthritis treatment on chronic opioid use
07/01/2022 - 10/30/2024 (Key Person / Mentor)
PI: Jean W. Liew, MD MSRheumatology Research Foundation
Healthy Knee Aging Vs. Osteoarthritis in Three Large Diverse Cohorts: What Is the Clinical Relevance of Structural Changes Seen on Radiographs?
09/27/2021 - 08/31/2024 (Subcontract PI)Arizona Board of Regents, University of Arizona NIH NIAMS1R01AR078187-01
Group-based mindfulness for patients with chronic low back pain in the primary care setting
09/01/2020 - 08/31/2024 (Subcontract PI)Boston Medical Center Corporation NIH NCCIH5UH3AT010621-03
Curriculum to Grow Diversity in the Rheumatology Workforce: Boston University Rheumatology
01/02/2023 - 12/31/2023 (Multi-PI)
PI: Tuhina Neogi, MD, PhDArthritis Foundation
A randomized, two-arm controlled, participant and investigator-blinded study investigating the efficacy, safety and tolerability of DFV890 in patients with symptomatic knee osteoarthritis
01/24/2022 - 11/30/2023 (PI)Novartis Pharmaceuticals Corporation
CARE (Creating and Advancing Research Equity) across BUSM
10/15/2021 - 10/14/2023 (Multi-PI)
PI: Tuhina Neogi, MD, PhDDoris Duke Charitable Foundation John Templeton Fdn
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Phase 3 multicenter, randomized, double-blind, placebo-controlled study to assess the efficacy
04/27/2020 - 04/27/2023 (PI)
Novartis Pharma Corp
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Publications listed below are automatically derived from MEDLINE/PubMed and other
sources, which might result in incorrect or missing publications. Faculty can
to make corrections and additions.
Showing 10 of 314 results.
Quinn KA, Ahlman MA, Alessi HD, LaValley MP, Neogi T, Marko J, Novakovich E, Grayson PC. Association of 18 F-Fluorodeoxyglucose-Positron Emission Tomography Activity With Angiographic Progression of Disease in Large Vessel Vasculitis. Arthritis Rheumatol. 2023 Jan; 75(1):98-107.View Related Profiles. PMID: 35792044; PMCID: PMC9797426; DOI: 10.1002/art.42290;
Jafarzadeh SR, Neogi T, White DK, Felson DT. The Relationship of Pain Reduction With Prevention of Knee Replacement Under Dynamic Intervention Strategies. Arthritis Rheumatol. 2022 Oct; 74(10):1668-1675.View Related Profiles. PMID: 35726122; PMCID: PMC9529798; DOI: 10.1002/art.42272;
Leach W, Doherty C, Olave M, England BR, Wysham K, Kerr G, Quinones M, Ogdie A, White D, Neogi T, Scanzello CR, Baker JF. Protocol for a multi-center randomized controlled trial to evaluate the benefits of exercise incentives and corticosteroid injections in osteoarthritis of the knee (MOVE-OK). Trials. 2022 Jul 27; 23(1):604. PMID: 35897080; PMCID: PMC9327347; DOI: 10.1186/s13063-022-06529-w;
Liew JW, Peloquin C, Tedeschi SK, Felson DT, Zhang Y, Choi HK, Terkeltaub R, Neogi T. Proton-Pump Inhibitors and Risk of Calcium Pyrophosphate Deposition in a Population-Based Study. Arthritis Care Res (Hoboken). 2022 Dec; 74(12):2059-2065.View Related Profiles. PMID: 35245410; PMCID: PMC9440954; DOI: 10.1002/acr.24876;
Williams EE, Katz JN, Leifer VP, Collins JE, Neogi T, Suter LG, Levy B, Farid A, Safran-Norton CE, Paltiel AD, Losina E. Cost-Effectiveness of Arthroscopic Partial Meniscectomy and Physical Therapy for Degenerative Meniscal Tear. ACR Open Rheumatol. 2022 Oct; 4(10):853-862.View Related Profiles. PMID: 35866194; PMCID: PMC9555200; DOI: 10.1002/acr2.11480;
Kim JS, Borges S, Clauw DJ, Conaghan PG, Felson DT, Fleming TR, Glaser R, Hart E, Hochberg M, Kim Y, Kraus VB, Lapteva L, Li X, Majumdar S, McAlindon TE, Mobasheri A, Neogi T, Roemer FW, Rothwell R, Shibuya R, Siegel J, Simon LS, Spindler KP, Nikolov NP. FDA/Arthritis Foundation osteoarthritis drug development workshop recap: Assessment of long-term benefit. Semin Arthritis Rheum. 2022 Oct; 56:152070.View Related Profiles. PMID: 35870222; PMCID: PMC9452453; DOI: 10.1016/j.semarthrit.2022.152070;
Tedeschi SK, Pascart T, Latourte A, Godsave C, Kundakci B, Naden RP, Taylor WJ, Dalbeth N, Neogi T, Perez-Ruiz F, Rosenthal A, Becce F, Pascual E, Andres M, Bardin T, Doherty M, Ea HK, Filippou G, FitzGerald J, Guitierrez M, Iagnocco A, Jansen TL, Kohler MJ, Lioté F, Matza M, McCarthy GM, Ramonda R, Reginato AM, Richette P, Singh JA, Sivera F, So A, Stamp LK, Yinh J, Yokose C, Terkeltaub R, Choi H, Abhishek A. Identifying Potential Classification Criteria for Calcium Pyrophosphate Deposition Disease: Item Generation and Item Reduction. Arthritis Care Res (Hoboken). 2022 Oct; 74(10):1649-1658. PMID: 33973414; PMCID: PMC8578594; DOI: 10.1002/acr.24619;
Gløersen M, Neogi T, Jafarzadeh SR, Sexton J, Haugen IK. Reply. Arthritis Rheumatol. 2022 Aug; 74(8):1454-1455.View Related Profiles. PMID: 35358373
Carlesso LC, Jafarzadeh SR, Stokes A, Felson DT, Wang N, Frey-Law L, Lewis CE, Nevitt M, Neogi T. Depressive symptoms and multi-joint pain partially mediate the relationship between obesity and opioid use in people with knee osteoarthritis. Osteoarthritis Cartilage. 2022 Sep; 30(9):1263-1269.View Related Profiles. PMID: 35700904; PMCID: PMC9419857; DOI: 10.1016/j.joca.2022.06.002;
Macri EM, Neogi T, Jarraya M, Guermazi A, Roemer F, Lewis CE, Torner JC, Lynch JA, Tolstykh I, Jafarzadeh SR, Stefanik JJ. Magnetic Resonance Imaging-Defined Osteoarthritis Features and Anterior Knee Pain in Individuals With, or at Risk for, Knee Osteoarthritis: A Multicenter Study on Osteoarthritis. Arthritis Care Res (Hoboken). 2022 Sep; 74(9):1533-1540.View Related Profiles. PMID: 33768706; PMCID: PMC8463633; DOI: 10.1002/acr.24604;
This graph shows the total number of publications by year, by first, middle/unknown,
or last author.
2022 Osteoarthritis Research Society International (OARSI):
Clinical Research Award
2021 Lund University, Sweden:
Honorary Degree: Doctor of Medicine, honoris causa
2020 Roxbury Society of Medical Information, elected member
2020 Boston University School of Medicine:
Alan S. Cohen Professor of Rheumatology (endowment)
2019 National Society of Clinical Rheumatology, elected member
2016 Boston University School of Medicine:
Robert Dawson Evans Research Mentoring Award
2014 American College of Rheumatology:
Henry Kunkel Young Investigator
2011 Osteoarthritis Research Society International:
Young Investigator Award
2009 Delta Omega Honor Society
2009 Arthritis Foundation:
J.V. Satterfield Research Award
2009 Boston University School of Medicine:
Robert Dawson Evans Junior Faculty Merit Award
1998 Alpha Omega Alpha Honor Medical Society
Available to Mentor as: (Review Mentor Role Definitions)
I have had an ongoing commitment to mentoring as evidenced by the successes of my mentees in obtaining career development grants, first-authored peer-reviewed publications, and presentations at national and international meetings. These mentoring efforts are complemented by a number of formal programs available at BUSM. Further, I helped spearhead the “Train the Mentors” program for which I served on the steering committee and act as a facilitator. I also developed and led the CTSI Research Career Support Program initiative, PRIME (Pathways to Research Independence and Mentoring Excellence), which aims to support early career mentored researchers to successfully transition to becoming independent investigators.
The majority of my mentoring activities occur within the Section of Rheumatology, which comprises a multidisciplinary team of senior faculty, junior investigators and additional staff dedicated to the conduct of research (e.g., project managers, research assistants, statistical programmers). I also serve on numerous Masters and PhD thesis committees for graduate students at the BU School of Public Health.
I received the 2016 Robert Dawson Evans Research Mentoring Award.
Co-Mentor or Peer Mentor
Research / Scholarly Mentor