Tuhina Neogi, MD, PhD
Professor
Boston University School of Medicine
Dept of Medicine
Rheumatology

MD, University of Toronto
PhD, Boston University School of Public Health




I am a rheumatologist and epidemiologist whose research has focused primarily on risk factors for knee osteoarthritis and gout, pain mechanisms in knee osteoarthritis, as well as methodologic issues of relevance for rheumatic diseases. I have had continuous peer-reviewed foundation and NIH funding since 2003, and have over 190 peer-reviewed publications to date. I am the most recent past chair of the FDA Arthritis Advisory Committee, serve on the boards two international societies: Osteoarthritis Research Society International (OARSI) and Gout, Hyperuricemia, and Crystal-Associated Diseases Network (G-CAN), and on committees for the American College of Rheumatology (ACR) and International Association for the Study Pain (IASP), among others. My work has been recognized with the prestigious 2014 ACR Henry Kunkel Young Investigator Award for outstanding and promising independent contributions to rheumatology research (awarded to no more than one clinical researcher and/or one basic science researcher each year). I have also engaged in developing new classification criteria for a number of rheumatic diseases. In addition to research, clinical work, and teaching, one of my key roles is to mentor trainees and junior faculty in musculoskeletal disease-related research. To that end, I was awarded the 2016 Robert Dawson Evans Research Mentoring Award. I am also leading the new CTSI Research Career Support Program initiative, PRIME (Pathways to Research Independence and Mentoring Excellence), which aims to support early career mentored researchers to successfully transition to becoming independent researchers.

Expertise includes:
- Osteoarthritis: epidemiology; risk factors; mechanisms of osteoarthritis-related pain; the role of bone in the pathophysiology of osteoarthritis
- Gout: epidemiology; risk factors and triggers for gout attacks; management of gout; consequences of gout and hyperuricemia
- Classification criteria and outcome measures in rheumatic diseases.
- Novel methodology to address challenging epidemiologic issues

Professor
Boston University School of Public Health
Epidemiology


Chief
Boston Medical Center
Medicine
Rheumatology

Investigator
Framingham Heart Study


Member
Boston University
Arthritis & Autoimmune Diseases Research Center


Member
Boston University
Evans Center for Interdisciplinary Biomedical Research


Section Chief of Rheumatology
Boston University School of Medicine
Medicine
Rheumatology


2016 Boston University School of Medicine: Robert Dawson Evans Research Mentoring Award
2014 American College of Rheumatology: Henry Kunkel Young Investigator
2011 Osteoarthritis Research Society International: Young Investigator Award
2009 Delta Omega Honor Society
2009 Arthritis Foundation: J.V. Satterfield Research Award
2009 Boston University School of Medicine: Robert Dawson Evans Junior Faculty Merit Award
1998 Alpha Omega Alpha Honor Medical Society


Optimizing the value of pain management in knee osteoarthritis patients with comorbidities
08/01/2018 - 06/30/2023 (Subcontract PI)
The Brigham and Women's Hospital, Inc. NIH NIAMS
5R01AR074290-02

The Role of Urate in Knee Osteoarthritis-Related Inflammation, Pathology and Pain
02/01/2017 - 06/30/2022 (PI)
NIH/National Institute of Arthritis & Musculoskeletal & Skin Diseases
5K24AR070892-03

Sprifermin Program
06/11/2018 - 12/31/2019 (PI)
EMD Serono Research & Development Institute, Inc.


Central Sensitization in Post-Knee Replacement Pain and Relation to OA Pathology
09/01/2016 - 08/31/2019 (PI)
NIH/National Institute of Arthritis & Musculoskeletal & Skin Diseases
4R01AR062506-05

Central Pain Mechanisms, Pain Intensity and Drug Response in Rheumatoid Arthritis
01/01/2018 - 06/30/2019 (Subcontract PI)
Northwestern University NIH NIAMS
7R01AR064850-06

Central Pain Mechanisms, Pain Intensity and Drug Response in Rheumatoid Arthritis
07/01/2016 - 12/31/2017 (Subcontract PI)
The Brigham and Women's Hospital, Inc. NIH NIAMS
5R01AR064850-05

Central Pain Mechanisms, Pain Intensity and Drug Response in Rheumatoid Arthritis
07/01/2013 - 06/30/2017 (Subcontract PI)
The Brigham and Women's Hospital, Inc. NIH NIAMS
5R01AR064850-03

Bisphosphate Effects in Knee Osteoarthritis
05/01/2014 - 04/30/2017 (PI)
Arthritis Foundation


Aromatase inhibitor-associated arthralgias: Characterization of the effect of estrogen depletion on pain
11/01/2015 - 01/31/2017 (PI)
Rheumatology Research Foundation


Central Sensitization in Post-knee replacement pain and relation to OA pathology
09/14/2012 - 08/31/2016 (PI)
NIH/National Institute of Arthritis & Musculoskeletal & Skin Diseases
5R01AR062506-04

Showing 10 of 17 results. Show All Results


Title


Yr Title Project-Sub Proj Pubs
2020 CAPSITE: Community Assessment of Pain and Sensitization in the Elderly 1R01AG066010-01
2019 The Role of Urate in Knee Osteoarthritis-Related Inflammation, Pathology and Pain 5K24AR070892-03 37
2018 The Role of Urate in Knee Osteoarthritis-Related Inflammation, Pathology and Pain 5K24AR070892-02 37
2017 The Role of Urate in Knee Osteoarthritis-Related Inflammation, Pathology and Pain 1K24AR070892-01 37
2016 Central Sensitization in Post-Knee Replacement Pain and Relation to OA Pathology 4R01AR062506-05 45
2016 Central sensitization in post-knee replacement pain and relation to OA pathology 4P60AR047785-15-6150 444
2015 Central Sensitization in Post-Knee Replacement Pain and Relation to OA Pathology 5R01AR062506-04 45
2015 Central sensitization in post-knee replacement pain and relation to OA pathology 5P60AR047785-14-6150 444
2014 Central Sensitization in Post-Knee Replacement Pain and Relation to OA Pathology 5R01AR062506-03 45
2014 Central sensitization in post-knee replacement pain and relation to OA pathology 5P60AR047785-13-6150 444
Showing 10 of 19 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Neogi T, Dalbeth N, Mikuls T, Turner A, Fitzgerald J. Reply to Letter to Editor (ar-20-0998): Gout Apathy Leads to Gout Arthropathy. Arthritis Rheumatol. 2020 Sep 16. PMID: 32936518
     
  2. Carlesso LC, Frey Law L, Wang N, Nevitt M, Lewis CE, Neogi T. The Association of Pain Sensitization and Conditioned Pain Modulation to Pain Patterns in Knee Osteoarthritis. Arthritis Care Res (Hoboken). 2020 Sep 03. PMID: 32882103
     
  3. Stamp LK, Chapman P, Frampton C, Duffull SB, Drake J, Zhang Y, Neogi T. Lack of effect of tart cherry concentrate dose on serum urate in people with gout. Rheumatology (Oxford). 2020 Sep 01; 59(9):2374-2380. PMID: 31891407
     
  4. Master H, Neogi T, Callahan LF, Nelson AE, LaValley M, Cleveland RJ, Golightly YM, Thoma LM, Zhang Y, Voinier D, Christiansen MB, Jakiela JT, Nevitt M, Lewis CE, Frey-Law LA, White DK. The association between walking speed from short- and standard-distance tests with the risk of all-cause mortality among adults with radiographic knee osteoarthritis: data from three large United States cohort studies. Osteoarthritis Cartilage. 2020 Aug 28.View Related Profiles. PMID: 32861851
     
  5. Jagpal A, Rahn EJ, Mudano AS, Dalbeth N, Taylor W, Saag KG, Singh JA, Cavagna L, Uhlig T, Perez-Ruiz F, McCarthy G, Gerritsen M, Stamp L, Vazquez Mellado J, Lin C, Vargas-Santos AB, Louthrenoo W, Neogi T, Chen YH, Castelar-Pinheiro GDR, Gaffo A. Which factors predict discordance between a patient and physician on a gout flare? Rheumatology (Oxford). 2020 Aug 13. PMID: 32793971
     
  6. Ballal P, Sury M, Lu N, Duryea J, Zhang Y, Ratzlaff C, Neogi T. The relation of oral bisphosphonates to bone marrow lesion volume among women with osteoarthritis. Osteoarthritis Cartilage. 2020 Aug 05. PMID: 32768598
     
  7. Zeng L, Qasim A, Neogi T, Fitzgerald JD, Dalbeth N, Mikuls TR, Guyatt GH, Brignardello-Petersen R. Comparative efficacy and safety of pharmacological interventions in patients experiencing a gout flare: a systematic review and network meta-analysis. Arthritis Care Res (Hoboken). 2020 Aug 02. PMID: 32741131
     
  8. Collins JE, Neogi T, Losina E. Rapid Structural Disease Progression in Knee Osteoarthritis Reply to Letter to the Editor. Arthritis Care Res (Hoboken). 2020 Jul 23.View Related Profiles. PMID: 32702195
     
  9. FitzGerald J, Brignardello-Petersen R, Dalbeth N, Mikuls T, Neogi T, Guyatt G. Author's response to Letter. Arthritis Care Res (Hoboken). 2020 Jul 23. PMID: 32702200
     
  10. Heisler AC, Song J, Dunlop DD, Wohlfahrt A, Bingham CO, Bolster MB, Clauw DJ, Marder W, Phillips K, Neogi T, Lee YC. Association of Pain Centralization and Patient-Reported Pain in Active Rheumatoid Arthritis. Arthritis Care Res (Hoboken). 2020 Aug; 72(8):1122-1129. PMID: 31162824
     
Showing 10 of 251 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 251 publications over 19 distinct years, with a maximum of 31 publications in 2018 and 2020

YearPublications
19981
20031
20042
20052
20068
20071
20089
20098
201013
201115
201218
201317
201417
201517
201624
201715
201831
201921
202031


Recent (within 3 months)

How to diagnose osteoarthritis and the role of imaging?

Joint Action 9/17/2020

How Top Experts Are Advancing Gout Care in the United States

Rheumatology Advisor 9/15/2020

Tuhina Neogi, MD, PhD, National Leader in Gout Management, on New ACR Guidelines

MedPage Today 9/8/2020

Coronavirus fears keep patients with severe chronic pain from seeking care

Axios 7/22/2020

Watch: The effect of the pandemic on chronic pain

AXIOS 7/14/2020

Older

New ACR Gout Guideline Boasts Better Evidence

MedPage Today 5/12/2020

New Studies Link Opioid Prescriptions to Obesity

Pharmacy Times 4/10/2020

Opioid Prescriptions Linked to Obesity

PsychCentral 4/7/2020

Obesity Increases Likelihood of Long-term Prescription Opioid Use, Researchers Find

Philly Voice 4/6/2020

Failure of Management: Treatment Gaps at the Root of Dismal Gout Care

Healio 12/16/2019

Three Quick Tips for Managing Osteoarthritis

Medscape 12/13/2019

Health Risks of NSAIDs Led to 'Significant Under-Treatment of Pain'

Pain News Network: 12/12/2019

ACR Releases Draft Gout Guideline

The Rheumatologist 11/20/2019

ACR, Arthritis Foundation Guidelines Favor Nondrug Therapy Over TENS, Stem Cells For OA

Healio 11/15/2019

Gout Guidelines Call For Treat-to-Target Strategy Using Allopurinol

Healio 11/15/2019

ACR Previews Updated Gout Practice Guideline

Rheumatology Consultant 11/13/2019

Outgoing President Touts OARSI Legacy, Renewed Drive To ‘Build Bridges’ Internationally

Healio 5/3/2019

Omega-3 Fatty Acids From Fish May Prevent Recurrent Gout Attacks

Medical Dialogues 5/1/2019

Dietary omega-3 fatty acids linked to lower risk of recurrent gout flare

Healio 4/18/2019

Why Boston's Brightest Industry Stars Are Throwing in the Towel

Boston Magazine 4/18/2019

Dietary omega-3 fatty acids linked to lower risk of recurrent gout flare

Healio 4/18/2019

Gout Outcomes Better With Nurse-Led Care

Renal & Urology News 10/19/2018

Study Sees No Link Between Gout Drug, Kidney Disease

Health Day 10/8/2018
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

epidemiology
gout
osteoarthritis
Spondyloarthritis

I have had an ongoing commitment to mentoring as evidenced by the successes of my mentees in obtaining career development grants, first-authored peer-reviewed publications, and presentations at national and international meetings. These mentoring efforts are complemented by a number of formal programs available at BUSM. Further, I helped spearhead the “Train the Mentors” program for which I serve on the steering committee and act as a facilitator. I am also the recipient of the 2016 Robert Dawson Evans Research Mentoring Award.

The majority of my mentoring activities occur within the Clinical Epidemiology Research and Training Unit, which comprises a multidisciplinary team of senior faculty, junior investigators and additional staff dedicated to the conduct of research (e.g., project managers, research assistants, statistical programmers). I also serve on numerous Masters and PhD thesis committees for graduate students at the BU School of Public Health.

I am now leading the CTSI Research Career Support Program initiative, PRIME (Pathways to Research Independence and Mentoring Excellence), which aims to support early career mentored researchers to successfully transition to becoming independent investigators.

Available to Mentor as: (Review Mentor Role Definitions):
  • Career Mentor
  • Co-Mentor or Peer Mentor
  • Project Mentor
  • Research / Scholarly Mentor
Contact for Mentoring:
  • Email (see 'Contact Info')

650 Albany St Evans Biomed Research Ctr
Boston MA 02118
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