Tuhina Neogi, MD, PhD
Professor
Boston University School of Medicine
Dept of Medicine
Rheumatology

MD, University of Toronto
PhD, Boston University School of Public Health




I am a rheumatologist and epidemiologist whose research has focused primarily on risk factors for knee osteoarthritis and gout, pain mechanisms in knee osteoarthritis, as well as methodologic issues of relevance for rheumatic diseases. I have had continuous peer-reviewed foundation and NIH funding since 2003, and have over 190 peer-reviewed publications to date. I am the most recent past chair of the FDA Arthritis Advisory Committee, serve on the boards two international societies: Osteoarthritis Research Society International (OARSI) and Gout, Hyperuricemia, and Crystal-Associated Diseases Network (G-CAN), and on committees for the American College of Rheumatology (ACR) and International Association for the Study Pain (IASP), among others. My work has been recognized with the prestigious 2014 ACR Henry Kunkel Young Investigator Award for outstanding and promising independent contributions to rheumatology research (awarded to no more than one clinical researcher and/or one basic science researcher each year). I have also engaged in developing new classification criteria for a number of rheumatic diseases. In addition to research, clinical work, and teaching, one of my key roles is to mentor trainees and junior faculty in musculoskeletal disease-related research. To that end, I was awarded the 2016 Robert Dawson Evans Research Mentoring Award. I am also leading the new CTSI Research Career Support Program initiative, PRIME (Pathways to Research Independence and Mentoring Excellence), which aims to support early career mentored researchers to successfully transition to becoming independent researchers.

Expertise includes:
- Osteoarthritis: epidemiology; risk factors; mechanisms of osteoarthritis-related pain; the role of bone in the pathophysiology of osteoarthritis
- Gout: epidemiology; risk factors and triggers for gout attacks; management of gout; consequences of gout and hyperuricemia
- Classification criteria and outcome measures in rheumatic diseases.
- Novel methodology to address challenging epidemiologic issues

Professor
Boston University School of Public Health
Epidemiology


Chief
Boston Medical Center
Medicine
Rheumatology

Investigator
Framingham Heart Study


Member
Boston University
Arthritis & Autoimmune Diseases Research Center


Member
Boston University
Evans Center for Interdisciplinary Biomedical Research


Section Chief of Rheumatology
Boston University School of Medicine
Medicine
Rheumatology


2016 Boston University School of Medicine: Robert Dawson Evans Research Mentoring Award
2014 American College of Rheumatology: Henry Kunkel Young Investigator
2011 Osteoarthritis Research Society International: Young Investigator Award
2009 Delta Omega Honor Society
2009 Arthritis Foundation: J.V. Satterfield Research Award
2009 Boston University School of Medicine: Robert Dawson Evans Junior Faculty Merit Award
1998 Alpha Omega Alpha Honor Medical Society


Pain in community-based older African American Adults: The Jackson Heart Study
09/30/2020 - 05/31/2025 (Multi-PI)
PI: Tuhina Neogi, MD, PhD
NIH/National Institute on Aging
1R01AG066914-01A1

CAPSITE: Community Assessment of Pain and Sensitization In The Elderly
01/01/2020 - 11/30/2024 (Multi-PI)
PI: Tuhina Neogi, MD, PhD
NIH/National Institute on Aging
1R01AG066010-01

Optimizing the value of pain management in knee osteoarthritis patients with comorbidities
08/01/2018 - 06/30/2023 (Subcontract PI)
The Brigham and Women's Hospital, Inc. NIH NIAMS
5R01AR074290-03

The Role of Urate in Knee Osteoarthritis-Related Inflammation, Pathology and Pain
02/01/2017 - 06/30/2022 (PI)
NIH/National Institute of Arthritis & Musculoskeletal & Skin Diseases
5K24AR070892-04

Wearable sensor-based Outcomes Following Physical Therapy in Knee Osteoarthritis: A Feasibility Study (WESENS-OA)
12/20/2019 - 12/31/2021 (PI)
Pfizer, Inc.


Pain sensitization in a trial of physical therapy for OA and meniscal tear
09/12/2019 - 08/30/2021 (Subcontract PI)
The Brigham and Women's Hospital, Inc. NIH NIAMS
5R21AR076156-02

Rapidly Progressive Osteoarthritis of the Knee – Frequency and Risk Factors: A Collaborative Epidemiology Study of the Pooled Osteoarthritis Initiative (OAI) and Multicenter Osteoarthritis Study (MOST
06/01/2020 - 06/01/2021 (PI)
Regeneron Pharmaceuticals, Inc.


Relation of allopurinol to renal function in patients with gout and chronic kidney disease
05/15/2020 - 05/01/2021 (PI)
Horizon Pharma USA


Group-based mindfulness for patients with chronic pain in the primary care setting
09/28/2019 - 08/31/2020 (Subcontract PI)
Boston Medical Center Corporation NIH NCCIH
1UG3AT010621-01

Sprifermin Program
06/11/2018 - 12/31/2019 (PI)
EMD Serono Research & Development Institute, Inc.


Showing 10 of 24 results. Show All Results


Title


Yr Title Project-Sub Proj Pubs
2020 CAPSITE: Community Assessment of Pain and Sensitization in the Elderly 1R01AG066010-01
2020 The Role of Urate in Knee Osteoarthritis-Related Inflammation, Pathology and Pain 5K24AR070892-04 37
2019 The Role of Urate in Knee Osteoarthritis-Related Inflammation, Pathology and Pain 5K24AR070892-03 37
2018 The Role of Urate in Knee Osteoarthritis-Related Inflammation, Pathology and Pain 5K24AR070892-02 37
2017 The Role of Urate in Knee Osteoarthritis-Related Inflammation, Pathology and Pain 1K24AR070892-01 37
2016 Central Sensitization in Post-Knee Replacement Pain and Relation to OA Pathology 4R01AR062506-05 45
2016 Central sensitization in post-knee replacement pain and relation to OA pathology 4P60AR047785-15-6150 444
2015 Central Sensitization in Post-Knee Replacement Pain and Relation to OA Pathology 5R01AR062506-04 45
2015 Central sensitization in post-knee replacement pain and relation to OA pathology 5P60AR047785-14-6150 444
2014 Central Sensitization in Post-Knee Replacement Pain and Relation to OA Pathology 5R01AR062506-03 45
Showing 10 of 20 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Jagpal A, Rahn EJ, Mudano AS, Dalbeth N, Taylor W, Saag KG, Singh JA, Cavagna L, Uhlig T, Perez-Ruiz F, McCarthy G, Gerritsen M, Stamp L, Vazquez Mellado J, Lin C, Vargas-Santos AB, Louthrenoo W, Neogi T, Chen YH, Castelar-Pinheiro GDR, Gaffo A. Which factors predict discordance between a patient and physician on a gout flare? Rheumatology (Oxford). 2021 Feb 01; 60(2):773-779. PMID: 32793971
     
  2. Fraenkel L, Wei Z, Ramsey C, Wiedmeyer C, Michaud K, Neogi T, Nowell WB, Venkatachalam S, Broniatowski DA. OPEX: Development of a novel overall patient experience measure to facilitate interpretation of comparison effectiveness studies. PLoS One. 2021; 16(1):e0245598. PMID: 33513209
     
  3. Stovall R, Peloquin C, Felson D, Neogi T, Dubreuil M. Relation of NSAID, DMARD and TNF-inhibitors for Ankylosing Spondylitis and Psoriatic Arthritis to Risk of Total Hip and Knee Arthroplasty. J Rheumatol. 2021 Jan 15.View Related Profiles. PMID: 33452168
     
  4. Choi HK, Neogi T, Stamp LK, Terkeltaub R, Dalbeth N. Reassessing the cardiovascular safety of febuxostat: implications of the FAST study. Arthritis Rheumatol. 2021 Jan 05. PMID: 33403821
     
  5. Thomas MJ, Yu D, Nicholls E, Bierma-Zeinstra S, Conaghan PG, Stoner KJ, Neogi T, Parry EL, Peat G. Short-Term Recovery Trajectories of Acute Flares in Knee Pain: A UK-Netherlands Multicenter Prospective Cohort Analysis. Arthritis Care Res (Hoboken). 2020 12; 72(12):1687-1692. PMID: 31600034
     
  6. Lenhard NK, Sullivan JK, Ross EL, Song S, Edwards RR, Hunter DJ, Neogi T, Katz JN, Losina E. Does screening for depressive symptoms help optimize duloxetine use in knee OA patients with moderate pain? A cost-effectiveness analysis. Arthritis Care Res (Hoboken). 2020 Nov 30.View Related Profiles. PMID: 33253496
     
  7. Kuusalo L, Felson DT, Wang N, Lewis CE, Torner J, Nevitt MC, Neogi T. Metabolic osteoarthritis - relation of diabetes and cardiovascular disease with knee osteoarthritis. Osteoarthritis Cartilage. 2021 Feb; 29(2):230-234.View Related Profiles. PMID: 33253888
     
  8. Singh JA, Neogi T, FitzGerald JD. Patient Perspectives on Gout and Gout Treatments: A Patient Panel Discussion That Informed the 2020 American College of Rheumatology Treatment Guideline. ACR Open Rheumatol. 2020 Dec; 2(12):725-733. PMID: 33222416
     
  9. Sinha P, Jafarzadeh SR, Assoumou SA, Bielick CG, Carpenter B, Garg S, Harleen S, Neogi T, Nishio MJ, Sagar M, Sharp V, Kissin EY. The effect of IL-6 inhibitors on mortality among hospitalized COVID-19 patients: a multicenter study. J Infect Dis. 2020 Nov 20.View Related Profiles. PMID: 33216906
     
  10. Heisler AC, Song J, Muhammad LN, Wohlfahrt A, Marder W, Bolster MB, Bingham CO, Clauw DJ, Dunlop DD, Neogi T, Lee YC. Association of Dysregulated Central Pain Processing and Response to Disease-Modifying Antirheumatic Drug Therapy in Rheumatoid Arthritis. Arthritis Rheumatol. 2020 12; 72(12):2017-2024. PMID: 32683800
     
Showing 10 of 262 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 262 publications over 20 distinct years, with a maximum of 39 publications in 2020

YearPublications
19981
20031
20042
20052
20068
20071
20089
20098
201013
201115
201218
201317
201417
201517
201624
201715
201831
201920
202039
20214


What Is the Criteria to Diagnose Rheumatoid Arthritis? What Patients Need to Know

Creaky Joints 10/15/2020

How Top Experts Are Advancing Gout Care in the United States

Renal & Urology News 9/29/2020

How to diagnose osteoarthritis and the role of imaging?

Joint Action 9/17/2020

How Top Experts Are Advancing Gout Care in the United States

Rheumatology Advisor 9/15/2020

Tuhina Neogi, MD, PhD, National Leader in Gout Management, on New ACR Guidelines

MedPage Today 9/8/2020

Coronavirus fears keep patients with severe chronic pain from seeking care

Axios 7/22/2020

Watch: The effect of the pandemic on chronic pain

AXIOS 7/14/2020

New ACR Gout Guideline Boasts Better Evidence

MedPage Today 5/12/2020

New Studies Link Opioid Prescriptions to Obesity

Pharmacy Times 4/10/2020

Opioid Prescriptions Linked to Obesity

PsychCentral 4/7/2020

Obesity Increases Likelihood of Long-term Prescription Opioid Use, Researchers Find

Philly Voice 4/6/2020

Failure of Management: Treatment Gaps at the Root of Dismal Gout Care

Healio 12/16/2019

Three Quick Tips for Managing Osteoarthritis

Medscape 12/13/2019

Health Risks of NSAIDs Led to 'Significant Under-Treatment of Pain'

Pain News Network: 12/12/2019

ACR Releases Draft Gout Guideline

The Rheumatologist 11/20/2019

ACR, Arthritis Foundation Guidelines Favor Nondrug Therapy Over TENS, Stem Cells For OA

Healio 11/15/2019

Gout Guidelines Call For Treat-to-Target Strategy Using Allopurinol

Healio 11/15/2019

ACR Previews Updated Gout Practice Guideline

Rheumatology Consultant 11/13/2019

Outgoing President Touts OARSI Legacy, Renewed Drive To ‘Build Bridges’ Internationally

Healio 5/3/2019

Omega-3 Fatty Acids From Fish May Prevent Recurrent Gout Attacks

Medical Dialogues 5/1/2019

Dietary omega-3 fatty acids linked to lower risk of recurrent gout flare

Healio 4/18/2019

Why Boston's Brightest Industry Stars Are Throwing in the Towel

Boston Magazine 4/18/2019

Dietary omega-3 fatty acids linked to lower risk of recurrent gout flare

Healio 4/18/2019

Gout Outcomes Better With Nurse-Led Care

Renal & Urology News 10/19/2018

Study Sees No Link Between Gout Drug, Kidney Disease

Health Day 10/8/2018
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

epidemiology
gout
osteoarthritis
Spondyloarthritis

I have had an ongoing commitment to mentoring as evidenced by the successes of my mentees in obtaining career development grants, first-authored peer-reviewed publications, and presentations at national and international meetings. These mentoring efforts are complemented by a number of formal programs available at BUSM. Further, I helped spearhead the “Train the Mentors” program for which I serve on the steering committee and act as a facilitator. I am also the recipient of the 2016 Robert Dawson Evans Research Mentoring Award.

The majority of my mentoring activities occur within the Clinical Epidemiology Research and Training Unit, which comprises a multidisciplinary team of senior faculty, junior investigators and additional staff dedicated to the conduct of research (e.g., project managers, research assistants, statistical programmers). I also serve on numerous Masters and PhD thesis committees for graduate students at the BU School of Public Health.

I am now leading the CTSI Research Career Support Program initiative, PRIME (Pathways to Research Independence and Mentoring Excellence), which aims to support early career mentored researchers to successfully transition to becoming independent investigators.

Available to Mentor as: (Review Mentor Role Definitions):
  • Career Mentor
  • Co-Mentor or Peer Mentor
  • Project Mentor
  • Research / Scholarly Mentor
Contact for Mentoring:
  • Email (see 'Contact Info')

650 Albany St Evans Biomed Research Ctr
Boston MA 02118
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