I am a rheumatologist and epidemiologist whose research has focused primarily on risk factors for knee osteoarthritis and gout, pain mechanisms in knee osteoarthritis, as well as methodologic issues of relevance for rheumatic diseases. I have had continuous peer-reviewed foundation and NIH funding since 2003, and have over 300 peer-reviewed publications to date. I am a past chair of the FDA Arthritis Advisory Committee, serve(d) on the boards two international societies: Osteoarthritis Research Society International (OARSI) and Gout, Hyperuricemia, and Crystal-Associated Diseases Network (G-CAN), and on committees for the American College of Rheumatology (ACR) and International Association for the Study Pain (IASP), among others. My work has been recognized with the prestigious 2014 ACR Henry Kunkel Young Investigator Award for outstanding and promising independent contributions to rheumatology research (awarded to no more than one clinical researcher and/or one basic science researcher each year), and the 2022 OARSI Clinical Research Award (in recognition of important contributions to OA research). I have also engaged in developing new classification criteria for a number of rheumatic diseases. In addition to research, clinical work, and teaching, one of my key roles is to mentor trainees and junior faculty in musculoskeletal disease-related research. To that end, I was awarded the 2016 Robert Dawson Evans Research Mentoring Award. I also developed and led the new CTSI Research Career Support Program initiative, PRIME (Pathways to Research Independence and Mentoring Excellence), which aims to support early career mentored researchers to successfully transition to becoming independent researchers.
- Osteoarthritis: epidemiology; risk factors; mechanisms of osteoarthritis-related pain; the role of bone in the pathophysiology of osteoarthritis
- Gout: epidemiology; risk factors and triggers for gout attacks; management of gout; consequences of gout and hyperuricemia
- Classification criteria and outcome measures in rheumatic diseases.
- Novel methodology to address challenging epidemiologic issues
Diversity, Equity, Inclusion and Accessibility
As Chief of Rheumatology, I have launched and supported a number of DEIA-related initiatives, including as examples: monthly Section-wide JEDI (Justice, Equity, Diversity, Inclusion) meeting involving staff, trainees, and faculty at which we address DEI topics of relevance to medicine, academia, work environment, interpersonal interactions, structural/systemic policies, etc.; a standardized and structured fellowship interview process with a DEI lens; programs focused on health equity for our patients.
At the institutional level, I serve/have served on: Women's Leadership Advisory Board, Diversity & Inclusion Advisory Council, BMC's Equity Acceleratory Research Working Group ("WG4")
COVID19-related DEI activities at BUMC:
- I am co-PI with Dr. Megan Bair-Merritt on the 2022 Doris Duke Charitable Foundation COVID-19 Fund to Retain Clinical Scientists to provide support to faculty whose research was disrupted by the adverse effects of the pandemic, compounded by caregiving responsibilities. (https://www.ddcf.org/news--insights/articles/largest-us-collaborative-funding-effort-for-equity-in-biomedicine-awards-$12.1-million-in-grants/)
- In the earliest phase of the COVID-19 pandemic, our patients at BMC were among the most affected people in the city, yet pharmaceutical companies were not bringing their clinical trials to our institution. I worked closely with a multidisciplinary group, the Clinical Trials Office, and BMC leadership to bring one of the first therapeutic trials to BMC to better serve our patients, who are often from backgrounds traditionally excluded from clinical trials. We were among the highest recruiting sites, and we had the most diversity, with >80% speaking a first-language other than English
Boston University School of Public Health
Boston Medical Center
Framingham Heart Study
Arthritis & Autoimmune Diseases Research Center
Evans Center for Interdisciplinary Biomedical Research
Section Chief of Rheumatology
Boston University Chobanian & Avedisian School of Medicine
Novel Insights into Osteoarthritis, Pain and Function: MOST 4
06/01/2023 - 02/29/2028 (Multi-PI)
PI: Tuhina Neogi, MD, PhDNIH/National Institute on Aging1U19AG076471-01A1
Identifying Determinants of Rapid Structural and/or Clinical Progression in Knee Osteoarthritis by Quantitative Assessment of Structural Features on Radiographs
08/12/2022 - 06/30/2027 (Multi-PI)
PI: Tuhina Neogi, MD, PhDUniversity of Arizona NIH NIAMS1R01AR080742-01
Boston University Rheumatology Research Training (BURRT) T32 Program
06/01/2022 - 05/31/2027 (PI)NIH/National Institute of Arthritis & Musculoskeletal & Skin Diseases5T32AR080623-02
QUC398A12201: A randomized, two-arm, placebo-controlled, participant, investigator and sponsor-blinded, proof-of-concept study investigating the efficacy, safety and tolerability of QUC398 in patients
05/16/2023 - 12/31/2026 (PI)Novartis Pharma AG
PRROPS: Pathways of Risk and Resilience for Overlapping Pain and Sensitization
07/15/2021 - 04/30/2026 (Multi-PI)
PI: Tuhina Neogi, MD, PhDNIH/National Institute of Neurological Disorders & Stroke5R01NS121419-02
The impact of axial spondyloarthritis treatment on chronic opioid use
07/01/2022 - 06/30/2025 (Key Person / Mentor)
PI: Jean W. Liew, MD MSRheumatology Research Foundation
Pain in community-based older African American Adults: The Jackson Heart Study
09/30/2020 - 05/31/2025 (Multi-PI)
PI: Tuhina Neogi, MD, PhDNIH/National Institute on Aging5R01AG066914-04
CAPSITE: Community Assessment of Pain and Sensitization in the Elderly
01/01/2020 - 11/30/2024 (Multi-PI)
PI: Tuhina Neogi, MD, PhDNIH/National Institute on Aging5R01AG066010-04
Healthy Knee Aging Vs. Osteoarthritis in Three Large Diverse Cohorts: What Is the Clinical Relevance of Structural Changes Seen on Radiographs?
09/27/2021 - 08/31/2024 (Subcontract PI)Arizona Board of Regents, University of Arizona NIH NIAMS1R01AR078187-01S1
Group-based mindfulness for patients with chronic low back pain in the primary care setting
09/01/2020 - 08/31/2024 (Subcontract PI)Boston Medical Center Corporation NIH NCCIH5UH3AT010621-03
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Phase 3 multicenter, randomized, double-blind, placebo-controlled study to assess the efficacy
04/27/2020 - 04/27/2023 (PI)
Novartis Pharma Corp
Showing 10 of 39 results.
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Publications listed below are automatically derived from MEDLINE/PubMed and other
sources, which might result in incorrect or missing publications. Faculty can
to make corrections and additions.
Showing 10 of 349 results.
Centor RM, Neogi T. Annals On Call - Low-Dose Colchicine and Incident Knee and Hip Replacements. Ann Intern Med. 2023 Oct 03; eA220019. PMID: 37782916
Aoyagi K, Jafarzadeh SR, Carlesso L, Frey Law L, Lewis CE, Nevitt M, Neogi T. Mediating Effect of Pain Sensitization on the Paradoxical Relation of Opioid Use to Pain Severity in Knee Osteoarthritis: The MOST Study. Arthritis Care Res (Hoboken). 2023 Sep 26.View Related Profiles. PMID: 37750238
Lee S, Neogi T, Costello KE, Senderling B, Stefanik JJ, Frey-Law L, Kumar D. Association of mechanical temporal summation of pain with muscle co-contraction during walking in people with knee osteoarthritis. Clin Biomech (Bristol, Avon). 2023 Sep 22; 110:106105.View Related Profiles. PMID: 37778085
Baker JF, Olave M, Leach W, Doherty CR, Gillcrist RL, White DK, Ogdie A, England BR, Wysham K, Quinones M, Xiao R, Neogi T, Scanzello CR. Corticosteroid Injections for Symptomatic Treatment of Osteoarthritis of the Knee: A Pilot Blinded Randomized Trial. ACR Open Rheumatol. 2023 Sep 22. PMID: 37740448
Neelapala YVR, Neogi T, Kumar D, Jarraya M, Macedo L, Kobsar D, Hanna S, Frey-Law LA, Lewis CE, Nevitt M, Appleton T, Birmingham T, Carlesso LC. Exploring different models of pain phenotypes and their association with pain worsening in people with early knee osteoarthritis: The MOST cohort study. Osteoarthritis Cartilage. 2023 Sep 13. PMID: 37709187
Neogi T, Colloca L. Placebo effects in osteoarthritis: implications for treatment and drug development. Nat Rev Rheumatol. 2023 Sep 11. PMID: 37697077
Modarresi S, Pearson N, Madden K, Bennell KL, Fahnestock M, Neogi T, Carlesso LC. Pain Informed Movement for people with knee osteoarthritis: Protocol for a pilot randomized controlled trial. Osteoarthr Cartil Open. 2023 Dec; 5(4):100402. PMID: 37664870; PMCID: PMC10469070; DOI: 10.1016/j.ocarto.2023.100402;
Abhishek A, Tedeschi SK, Pascart T, Latourte A, Dalbeth N, Neogi T, Fuller A, Rosenthal A, Becce F, Bardin T, Ea HK, Filippou G, FitzGerald J, Iagnocco A, Lioté F, McCarthy GM, Ramonda R, Richette P, Sivera F, Andres M, Cipolletta E, Doherty M, Pascual E, Perez-Ruiz F, So A, Jansen TL, Kohler MJ, Stamp LK, Yinh J, Adinolfi A, Arad U, Aung T, Benillouche E, Bortoluzzi A, Dau J, Maningding E, Fang MA, Figus FA, Filippucci E, Haslett J, Janssen M, Kaldas M, Kimoto M, Leamy K, Navarro GM, Sarzi-Puttini P, Scirè C, Silvagni E, Sirotti S, Stack JR, Truong L, Xie C, Yokose C, Hendry AM, Terkeltaub R, Taylor WJ, Choi HK. The 2023 ACR/EULAR Classification Criteria for Calcium Pyrophosphate Deposition Disease. Arthritis Rheumatol. 2023 Oct; 75(10):1703-1713. PMID: 37494275; PMCID: PMC10543651; DOI: 10.1002/art.42619;
Abhishek A, Tedeschi SK, Pascart T, Latourte A, Dalbeth N, Neogi T, Fuller A, Rosenthal A, Becce F, Bardin T, Ea HK, Filippou G, Fitzgerald J, Iagnocco A, Lioté F, McCarthy GM, Ramonda R, Richette P, Sivera F, Andrés M, Cipolletta E, Doherty M, Pascual E, Perez-Ruiz F, So A, Jansen TL, Kohler MJ, Stamp LK, Yinh J, Adinolfi A, Arad U, Aung T, Benillouche E, Bortoluzzi A, Dau J, Maningding E, Fang MA, Figus FA, Filippucci E, Haslett J, Janssen M, Kaldas M, Kimoto M, Leamy K, Navarro GM, Sarzi-Puttini P, Scirè C, Silvagni E, Sirotti S, Stack JR, Truong L, Xie C, Yokose C, Hendry AM, Terkeltaub R, Taylor WJ, Choi HK. The 2023 ACR/EULAR classification criteria for calcium pyrophosphate deposition disease. Ann Rheum Dis. 2023 Oct; 82(10):1248-1257. PMID: 37495237; PMCID: PMC10529191; DOI: 10.1136/ard-2023-224575;
Gløersen M, Steen Pettersen P, Neogi T, Sexton J, Kvien TK, Hammer HB, Haugen IK. Associations between pain sensitization and measures of physical function in people with hand osteoarthritis: Results from the Nor-Hand study. Osteoarthritis Cartilage. 2023 Oct; 31(10):1388-1395. PMID: 37495183; PMCID: PMC10528207; DOI: 10.1016/j.joca.2023.07.005;
This graph shows the total number of publications by year, by first, middle/unknown,
or last author.
2022 Osteoarthritis Research Society International (OARSI):
Clinical Research Award
2021 Lund University, Sweden:
Honorary Degree: Doctor of Medicine, honoris causa
2020 Roxbury Society of Medical Information, elected member
2020 Boston University School of Medicine:
Alan S. Cohen Professor of Rheumatology (endowment)
2019 National Society of Clinical Rheumatology, elected member
2016 Boston University School of Medicine:
Robert Dawson Evans Research Mentoring Award
2014 American College of Rheumatology:
Henry Kunkel Young Investigator
2011 Osteoarthritis Research Society International:
Young Investigator Award
2009 Delta Omega Honor Society
2009 Arthritis Foundation:
J.V. Satterfield Research Award
2009 Boston University School of Medicine:
Robert Dawson Evans Junior Faculty Merit Award
1998 Alpha Omega Alpha Honor Medical Society
Available to Mentor as: (Review Mentor Role Definitions)
I have had an ongoing commitment to mentoring as evidenced by the successes of my mentees in obtaining career development grants, first-authored peer-reviewed publications, and presentations at national and international meetings. These mentoring efforts are complemented by a number of formal programs available at BUSM. Further, I helped spearhead the “Train the Mentors” program for which I served on the steering committee and act as a facilitator. I also developed and led the CTSI Research Career Support Program initiative, PRIME (Pathways to Research Independence and Mentoring Excellence), which aims to support early career mentored researchers to successfully transition to becoming independent investigators.
The majority of my mentoring activities occur within the Section of Rheumatology, which comprises a multidisciplinary team of senior faculty, junior investigators and additional staff dedicated to the conduct of research (e.g., project managers, research assistants, statistical programmers). I also serve on numerous Masters and PhD thesis committees for graduate students at the BU School of Public Health.
I received the 2016 Robert Dawson Evans Research Mentoring Award.
Co-Mentor or Peer Mentor
Research / Scholarly Mentor