Tuhina Neogi, MD, PhD
Professor
Boston University School of Medicine
Dept of Medicine
Clinical Epi Research & Training

MD, University of Toronto
PhD, Boston University School of Public Health



I am a rheumatologist and epidemiologist whose research has focused primarily on risk factors for knee osteoarthritis and gout, pain mechanisms in knee osteoarthritis, as well as methodologic issues of relevance for rheumatic diseases. I have had continuous peer-reviewed foundation and NIH funding since 2003, and have over 190 peer-reviewed publications to date. I am the most recent past chair of the FDA Arthritis Advisory Committee, serve on the boards two international societies: Osteoarthritis Research Society International (OARSI) and Gout, Hyperuricemia, and Crystal-Associated Diseases Network (G-CAN), and on committees for the American College of Rheumatology (ACR) and International Association for the Study Pain (IASP), among others. My work has been recognized with the prestigious 2014 ACR Henry Kunkel Young Investigator Award for outstanding and promising independent contributions to rheumatology research (awarded to no more than one clinical researcher and/or one basic science researcher each year). I have also engaged in developing new classification criteria for a number of rheumatic diseases. In addition to research, clinical work, and teaching, one of my key roles is to mentor trainees and junior faculty in musculoskeletal disease-related research. To that end, I was awarded the 2016 Robert Dawson Evans Research Mentoring Award. I am also leading the new CTSI Research Career Support Program initiative, PRIME (Pathways to Research Independence and Mentoring Excellence), which aims to support early career mentored researchers to successfully transition to becoming independent researchers.

Expertise includes:
- Osteoarthritis: epidemiology; risk factors; mechanisms of osteoarthritis-related pain; the role of bone in the pathophysiology of osteoarthritis
- Gout: epidemiology; risk factors and triggers for gout attacks; management of gout; consequences of gout and hyperuricemia
- Classification criteria and outcome measures in rheumatic diseases.
- Novel methodology to address challenging epidemiologic issues

Professor
Boston University School of Public Health
Epidemiology


Attending Physician
Boston Medical Center
Medicine
Rheumatology (Arthritis)


2016 Boston University School of Medicine: Robert Dawson Evans Research Mentoring Award
2014 American College of Rheumatology: Henry Kunkel Young Investigator
2011 Osteoarthritis Research Society International: Young Investigator Award
2009 Delta Omega Honor Society
2009 Arthritis Foundation: J.V. Satterfield Research Award
2009 Boston University School of Medicine: Robert Dawson Evans Junior Faculty Merit Award
1998 Alpha Omega Alpha Honor Medical Society


THE ROLE OF URATE IN KNEE OSTEOARTHRITIS-RELATED INFLAMMATION, PATHOLOGY AND PAIN
02/01/2017 - 12/31/2021 (PI)
NIH/National Institute of Arthritis & Musculoskeletal & Skin Diseases
5K24AR070892-02

CENTRAL SENSITIZATION IN POST-KNEE REPLACEMENT PAIN AND RELATION TO OA PATHOLOGY
09/01/2016 - 08/31/2019 (PI)
NIH/National Institute of Arthritis & Musculoskeletal & Skin Diseases
4R01AR062506-05

CENTRAL PAIN MECHANISMS, PAIN INTENSITY AND DRUG RESPONSE IN RHEUMATOID ARTHRITIS
01/01/2018 - 06/30/2019 (PI)
Northwestern University NIH NIAMS
7R01AR064850-06

SPRIFERMIN PROGRAM
06/11/2018 - 09/10/2018 (PI)
EMD Serono Research & Development Institute, Inc.

CENTRAL PAIN MECHANISMS, PAIN INTENSITY AND DRUG RESPONSE IN RHEUMATOID ARTHRITIS
07/01/2016 - 12/31/2017 (PI)
The Brigham and Women's Hospital, Inc. NIH NIAMS
4R01AR064850-04

CENTRAL PAIN MECHANISMS, PAIN INTENSITY AND DRUG RESPONSE IN RHEUMATOID ARTHRITIS
07/01/2013 - 06/30/2017 (PI)
The Brigham and Women's Hospital, Inc. NIH NIAMS
5R01AR064850-03

BISPHOSPHATE EFFECTS IN KNEE OSTEOARTHRITIS
05/01/2014 - 04/30/2017 (PI)
Arthritis Foundation

AROMATASE INHIBITOR-ASSOCIATED ARTHRALGIAS: CHARACTERIZATION OF THE EFFECT OF ESTROGEN DEPLETION ON PAIN
11/01/2015 - 01/31/2017 (PI)
Rheumatology Research Foundation

CENTRAL SENSITIZATION IN POST-KNEE REPLACEMENT PAIN AND RELATION TO OA PATHOLOGY
09/14/2012 - 08/31/2016 (PI)
NIH/National Institute of Arthritis & Musculoskeletal & Skin Diseases
5R01AR062506-04

NIAMS MULTIDISCIPLINARY CLINICAL RESEARCH CENTER
08/01/2012 - 07/31/2016 (SP Co-PI of Sub-Project / SP)
PI: David T. Felson, MD, MPH
NIH/National Institute of Arthritis & Musculoskeletal & Skin Diseases
5P60AR047785-14

Showing 10 of 16 results. Show All Results



Yr Title Project-Sub Proj Pubs
2018 The Role of Urate in Knee Osteoarthritis-Related Inflammation, Pathology and Pain 5K24AR070892-02
2017 The Role of Urate in Knee Osteoarthritis-Related Inflammation, Pathology and Pain 1K24AR070892-01
2016 Central Sensitization in Post-Knee Replacement Pain and Relation to OA Pathology 4R01AR062506-05 17
2016 Central sensitization in post-knee replacement pain and relation to OA pathology 4P60AR047785-15-6150 308
2015 Central Sensitization in Post-Knee Replacement Pain and Relation to OA Pathology 5R01AR062506-04 17
2015 Central sensitization in post-knee replacement pain and relation to OA pathology 5P60AR047785-14-6150 308
2014 Central Sensitization in Post-Knee Replacement Pain and Relation to OA Pathology 5R01AR062506-03 17
2014 Central sensitization in post-knee replacement pain and relation to OA pathology 5P60AR047785-13-6150 308
2013 Central Sensitization in Post-Knee Replacement Pain and Relation to OA Pathology 5R01AR062506-02 17
2013 Central sensitization in post-knee replacement pain and relation to OA pathology 5P60AR047785-12-6150 308
Showing 10 of 17 results. Show All Results
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Thomas MJ, Butler-Walley S, Rathod-Mistry T, Mayson Z, Parry EL, Pope C, Neogi T, Peat G. Acute flares of knee osteoarthritis in primary care: a feasibility and pilot case-crossover study. Pilot Feasibility Stud. 2018; 4:167. PMID: 30410785.
     
  2. Vargas-Santos AB, Peloquin CE, Zhang Y, Neogi T. Association of Chronic Kidney Disease With Allopurinol Use in Gout Treatment. JAMA Intern Med. 2018 Nov 01; 178(11):1526-1533. PMID: 30304329.
     
  3. Choi H, Neogi T, Stamp L, Dalbeth N, Terkeltaub R. New Perspectives in Rheumatology: Implications of the Cardiovascular Safety of Febuxostat and Allopurinol in Patients With Gout and Cardiovascular Morbidities Trial and the Associated Food and Drug Administration Public Safety Alert. Arthritis Rheumatol. 2018 Nov; 70(11):1702-1709. PMID: 29869840.
     
  4. Neogi T, Dalbeth N. Patient education and engagement in treat-to-target gout care. Lancet. 2018 10 20; 392(10156):1379-1381. PMID: 30343848.
     
  5. Carlesso LC, Segal NA, Frey-Law L, Zhang Y, Lu N, Nevitt M, Lewis CE, Neogi T. Pain Susceptibility Phenotypes in Those Free of Knee Pain with or at Risk of Knee Osteoarthritis: The Multicenter Osteoarthritis Study. Arthritis Rheumatol. 2018 Oct 11. PMID: 30307131.
     
  6. Choi H, Neogi T, Stamp L, Dalbeth N, Terkeltaub R. Authors' Reply to Letter to the Editor. Arthritis Rheumatol. 2018 Oct 08. PMID: 30295436.
     
  7. Svensson F, Felson DT, Zhang F, Guermazi A, Roemer FW, Niu J, Aliabadi P, Neogi T, Englund M. Meniscal body extrusion and cartilage coverage in middle-aged and elderly without radiographic knee osteoarthritis. Eur Radiol. 2018 Oct 02.View Related Profiles. PMID: 30280250.
     
  8. Stefanik JJ, Felson DT, Apovian CM, Niu J, Margaret Clancy M, LaValley MP, Neogi T. Changes in Pain Sensitization After Bariatric Surgery. Arthritis Care Res (Hoboken). 2018 Oct; 70(10):1525-1528.View Related Profiles. PMID: 29316386.
     
  9. Suri P, Palmer MR, Tsepilov YA, Freidin MB, Boer CG, Yau MS, Evans DS, Gelemanovic A, Bartz TM, Nethander M, Arbeeva L, Karssen L, Neogi T, Campbell A, Mellstrom D, Ohlsson C, Marshall LM, Orwoll E, Uitterlinden A, Rotter JI, Lauc G, Psaty BM, Karlsson MK, Lane NE, Jarvik GP, Polasek O, Hochberg M, Jordan JM, Van Meurs JBJ, Jackson R, Nielson CM, Mitchell BD, Smith BH, Hayward C, Smith NL, Aulchenko YS, Williams FMK. Genome-wide meta-analysis of 158,000 individuals of European ancestry identifies three loci associated with chronic back pain. PLoS Genet. 2018 Sep; 14(9):e1007601. PMID: 30261039.
     
  10. Zhang M, Solomon DH, Desai RJ, Kang EH, Liu J, Neogi T, Kim SC. Assessment of Cardiovascular Risk in Older Patients With Gout Initiating Febuxostat Versus Allopurinol. Circulation. 2018 Sep 11; 138(11):1116-1126. PMID: 29899013.
     
Showing 10 of 200 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 200 publications over 17 distinct years, with a maximum of 32 publications in 2018

YearPublications
19981
20031
20042
20052
20068
20071
20089
20098
201013
201115
201218
201317
201417
201517
201624
201715
201832
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

epidemiology
gout
osteoarthritis

I have had an ongoing commitment to mentoring as evidenced by the successes of my mentees in obtaining career development grants, first-authored peer-reviewed publications, and presentations at national and international meetings. These mentoring efforts are complemented by a number of formal programs available at BUSM. Further, I helped spearhead the “Train the Mentors” program for which I serve on the steering committee and act as a facilitator. I am also the recipient of the 2016 Robert Dawson Evans Research Mentoring Award.

The majority of my mentoring activities occur within the Clinical Epidemiology Research and Training Unit, which comprises a multidisciplinary team of senior faculty, junior investigators and additional staff dedicated to the conduct of research (e.g., project managers, research assistants, statistical programmers). I also serve on numerous Masters and PhD thesis committees for graduate students at the BU School of Public Health.

I am now leading the CTSI Research Career Support Program initiative, PRIME (Pathways to Research Independence and Mentoring Excellence), which aims to support early career mentored researchers to successfully transition to becoming independent investigators.

Available to Mentor as: (Review Mentor Role Definitions):
  • Career Mentor
  • Co-Mentor or Peer Mentor
  • Project Mentor
  • Research / Scholarly Mentor
Contact for Mentoring:
  • Email (see 'Contact Info')


Recent (within 3 months)

Gout Outcomes Better With Nurse-Led Care

Renal & Urology News 10/19/2018

Study Sees No Link Between Gout Drug, Kidney Disease

Health Day 10/8/2018

650 Albany St Evans Biomed Research Ctr
Boston MA 02118
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