Tuhina Neogi, MD, PhD Hear my name
Boston University Chobanian & Avedisian School of Medicine

MD, University of Toronto
PhD, Boston University School of Public Health
BS, McMaster University

I am a rheumatologist and epidemiologist whose research has focused primarily on risk factors for knee osteoarthritis and gout, pain mechanisms in knee osteoarthritis, as well as methodologic issues of relevance for rheumatic diseases. I have had continuous peer-reviewed foundation and NIH funding since 2003, and have over 300 peer-reviewed publications to date. I am a past chair of the FDA Arthritis Advisory Committee, serve(d) on the boards two international societies: Osteoarthritis Research Society International (OARSI) and Gout, Hyperuricemia, and Crystal-Associated Diseases Network (G-CAN), and on committees for the American College of Rheumatology (ACR) and International Association for the Study Pain (IASP), among others. My work has been recognized with the prestigious 2014 ACR Henry Kunkel Young Investigator Award for outstanding and promising independent contributions to rheumatology research (awarded to no more than one clinical researcher and/or one basic science researcher each year), and the 2022 OARSI Clinical Research Award (in recognition of important contributions to OA research). I have also engaged in developing new classification criteria for a number of rheumatic diseases. In addition to research, clinical work, and teaching, one of my key roles is to mentor trainees and junior faculty in musculoskeletal disease-related research. To that end, I was awarded the 2016 Robert Dawson Evans Research Mentoring Award. I also developed and led the new CTSI Research Career Support Program initiative, PRIME (Pathways to Research Independence and Mentoring Excellence), which aims to support early career mentored researchers to successfully transition to becoming independent researchers.

Expertise includes:
- Osteoarthritis: epidemiology; risk factors; mechanisms of osteoarthritis-related pain; the role of bone in the pathophysiology of osteoarthritis
- Gout: epidemiology; risk factors and triggers for gout attacks; management of gout; consequences of gout and hyperuricemia
- Classification criteria and outcome measures in rheumatic diseases.
- Novel methodology to address challenging epidemiologic issues

Diversity, Equity, Inclusion and Accessibility

As Chief of Rheumatology, I have launched and supported a number of DEIA-related initiatives, including as examples: monthly Section-wide JEDI (Justice, Equity, Diversity, Inclusion) meeting involving staff, trainees, and faculty at which we address DEI topics of relevance to medicine, academia, work environment, interpersonal interactions, structural/systemic policies, etc.; a standardized and structured fellowship interview process with a DEI lens; programs focused on health equity for our patients.

At the institutional level, I serve/have served on: Women's Leadership Advisory Board, Diversity & Inclusion Advisory Council, BMC's Equity Acceleratory Research Working Group ("WG4")

COVID19-related DEI activities at BUMC:
- I am co-PI with Dr. Megan Bair-Merritt on the 2022 Doris Duke Charitable Foundation COVID-19 Fund to Retain Clinical Scientists to provide support to faculty whose research was disrupted by the adverse effects of the pandemic, compounded by caregiving responsibilities. (https://www.ddcf.org/news--insights/articles/largest-us-collaborative-funding-effort-for-equity-in-biomedicine-awards-$12.1-million-in-grants/)
- In the earliest phase of the COVID-19 pandemic, our patients at BMC were among the most affected people in the city, yet pharmaceutical companies were not bringing their clinical trials to our institution. I worked closely with a multidisciplinary group, the Clinical Trials Office, and BMC leadership to bring one of the first therapeutic trials to BMC to better serve our patients, who are often from backgrounds traditionally excluded from clinical trials. We were among the highest recruiting sites, and we had the most diversity, with >80% speaking a first-language other than English

Boston University School of Public Health

Boston Medical Center

Framingham Heart Study

Boston University
Arthritis & Autoimmune Diseases Research Center

Boston University
Evans Center for Interdisciplinary Biomedical Research

Section Chief of Rheumatology
Boston University Chobanian & Avedisian School of Medicine

Novel Insights into Osteoarthritis, Pain and Function: MOST 4
06/01/2023 - 02/29/2028 (Multi-PI)
PI: Tuhina Neogi, MD, PhD
NIH/National Institute on Aging

Identifying Determinants of Rapid Structural and/or Clinical Progression in Knee Osteoarthritis by Quantitative Assessment of Structural Features on Radiographs
08/12/2022 - 06/30/2027 (Multi-PI)
PI: Tuhina Neogi, MD, PhD
University of Arizona NIH NIAMS

Boston University Rheumatology Research Training (BURRT) T32 Program
06/01/2022 - 05/31/2027 (PI)
NIH/National Institute of Arthritis & Musculoskeletal & Skin Diseases

QUC398A12201: A randomized, two-arm, placebo-controlled, participant, investigator and sponsor-blinded, proof-of-concept study investigating the efficacy, safety and tolerability of QUC398 in patients
05/16/2023 - 12/31/2026 (PI)
Novartis Pharma AG

PRROPS: Pathways of Risk and Resilience for Overlapping Pain and Sensitization
07/15/2021 - 04/30/2026 (Multi-PI)
PI: Tuhina Neogi, MD, PhD
NIH/National Institute of Neurological Disorders & Stroke

The impact of axial spondyloarthritis treatment on chronic opioid use
07/01/2022 - 06/30/2025 (Key Person / Mentor)
PI: Jean W. Liew, MD MS
Rheumatology Research Foundation

Pain in community-based older African American Adults: The Jackson Heart Study
09/30/2020 - 05/31/2025 (Multi-PI)
PI: Tuhina Neogi, MD, PhD
NIH/National Institute on Aging

CAPSITE: Community Assessment of Pain and Sensitization in the Elderly
01/01/2020 - 11/30/2024 (Multi-PI)
PI: Tuhina Neogi, MD, PhD
NIH/National Institute on Aging

Healthy Knee Aging Vs. Osteoarthritis in Three Large Diverse Cohorts: What Is the Clinical Relevance of Structural Changes Seen on Radiographs?
09/27/2021 - 08/31/2024 (Subcontract PI)
Arizona Board of Regents, University of Arizona NIH NIAMS

Group-based mindfulness for patients with chronic low back pain in the primary care setting
09/01/2020 - 08/31/2024 (Subcontract PI)
Boston Medical Center Corporation NIH NCCIH

Showing 10 of 38 results. Show All Results

Phase 3 multicenter, randomized, double-blind, placebo-controlled study to assess the efficacy
04/27/2020 - 04/27/2023 (PI)
Novartis Pharma Corp


Yr Title Project-Sub Proj Pubs
2024 Project 1: Impaired Exercise Induced Hypoalgesia 5U19AG076471-02-8205
2024 Project 3: Intraarticular Mineralization 5U19AG076471-02-8207
2024 Novel Insights into Osteoarthritis, Pain and Function: MOST4 5U19AG076471-02
2023 Identifying determinants of rapid structural and/or clinical progression in knee osteoarthritis by quantitative assessment of structural features on radiographs 3R01AR080742-02S1
2023 Project 3: Intraarticular Mineralization 1U19AG076471-01A1-8207
2023 Project 1: Impaired Exercise Induced Hypoalgesia 1U19AG076471-01A1-8205
2023 Novel Insights into Osteoarthritis, Pain and Function: MOST4 1U19AG076471-01A1
2023 Identifying determinants of rapid structural and/or clinical progression in knee osteoarthritis by quantitative assessment of structural features on radiographs 5R01AR080742-02
2023 Boston University Rheumatology Research Training (BURRT) T32 Program 5T32AR080623-02
2023 Pain in community-based older African American Adults: The Jackson Heart Study 5R01AG066914-04
Showing 10 of 42 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Mahmoudian A, King LK, Liew JW, Wang Q, Appleton CT, Englund M, Haugen IK, Lohmander LS, Runhaar J, Turkiewicz A, Neogi T, Hawker GA. Timing is everything: Towards classification criteria for early-stage symptomatic knee osteoarthritis. Osteoarthritis Cartilage. 2024 Mar 02.View Related Profiles. PMID: 38437945
  2. Liew JW, Jarraya M, Guermazi A, Lynch J, Felson D, Nevitt M, Lewis CE, Torner J, Roemer FW, Crema MD, Wang N, Becce F, Rabasa G, Pascart T, Neogi T. Intra-Articular Mineralization on Computerized Tomography of the Knee and Risk of Cartilage Damage: The Multicenter Osteoarthritis Study. Arthritis Rheumatol. 2024 Feb 19.View Related Profiles. PMID: 38369918
  3. Aoyagi K, Jafarzadeh SR, Carlesso L, Frey Law L, Lewis CE, Nevitt M, Neogi T. Mediating Effect of Pain Sensitization on the Paradoxical Relation of Taking Opioids to Pain Severity in Knee Osteoarthritis: The Multicenter Osteoarthritis Study. Arthritis Care Res (Hoboken). 2024 Mar; 76(3):403-408.View Related Profiles. PMID: 37750238; PMCID: PMC10922135; DOI: 10.1002/acr.25244;
  4. Helget LN, O'Dell JR, Newcomb JA, Androsenko M, Brophy MT, Davis-Karim A, England BR, Ferguson R, Pillinger MH, Neogi T, Palevsky PM, Wu H, Kramer B, Mikuls TR. Determinants of Achieving Serum Urate Goal with Treat-to-Target Urate-Lowering Therapy in Gout. Arthritis Rheumatol. 2024 Apr; 76(4):638-646.View Related Profiles. PMID: 37842953; PMCID: PMC10965366; DOI: 10.1002/art.42731;
  5. Liew JW, Jarraya M, Guermazi A, Lynch J, Wang N, Rabasa G, Jafarzadeh SR, Nevitt M, Torner J, Lewis CE, Felson DT, Neogi T. Relation of Intra-Articular Mineralization to Knee Pain in Knee Osteoarthritis: A Longitudinal Analysis in the MOST Study. Arthritis Rheumatol. 2023 Dec; 75(12):2161-2168.View Related Profiles. PMID: 37410792; PMCID: PMC10770289; DOI: 10.1002/art.42649;
  6. Centor RM, Neogi T. Web Exclusive. Annals On Call - Low-Dose Colchicine and Incident Knee and Hip Replacements. Ann Intern Med. 2023 Oct; 176(10):eA220019. PMID: 37782916
  7. Lee S, Neogi T, Costello KE, Senderling B, Stefanik JJ, Frey-Law L, Kumar D. Association of mechanical temporal summation of pain with muscle co-contraction during walking in people with knee osteoarthritis. Clin Biomech (Bristol, Avon). 2023 Dec; 110:106105.View Related Profiles. PMID: 37778085; PMCID: PMC10841902; DOI: 10.1016/j.clinbiomech.2023.106105;
  8. Baker JF, Olave M, Leach W, Doherty CR, Gillcrist RL, White DK, Ogdie A, England BR, Wysham K, Quinones M, Xiao R, Neogi T, Scanzello CR. Corticosteroid Injections for Symptomatic Treatment of Osteoarthritis of the Knee: A Pilot Blinded Randomized Trial. ACR Open Rheumatol. 2023 Oct; 5(10):529-535. PMID: 37740448; PMCID: PMC10570668; DOI: 10.1002/acr2.11596;
  9. Neelapala YVR, Neogi T, Kumar D, Jarraya M, Macedo L, Kobsar D, Hanna S, Frey-Law LA, Lewis CE, Nevitt M, Appleton T, Birmingham T, Carlesso LC. Exploring different models of pain phenotypes and their association with pain worsening in people with early knee osteoarthritis: The MOST cohort study. Osteoarthritis Cartilage. 2024 Feb; 32(2):210-219. PMID: 37709187; PMCID: PMC10903761; DOI: 10.1016/j.joca.2023.09.003;
  10. Neogi T, Colloca L. Placebo effects in osteoarthritis: implications for treatment and drug development. Nat Rev Rheumatol. 2023 Oct; 19(10):613-626. PMID: 37697077; PMCID: PMC10615856; DOI: 10.1038/s41584-023-01021-4;
Showing 10 of 354 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 354 publications over 23 distinct years, with a maximum of 38 publications in 2022


Recent (within 3 months)

CT-detected knee cartilage mineralization predicts MRI cartilage worsening in same area

Healio 3/27/2024

What Causes Osteoarthritis? BU Researchers Win $46 Million Grant to Pursue Answers and Find New Treatments

The Brink 3/20/2024

Calcium Crystals in Knee Could Be Worsening Arthritis

Health Day 3/1/2024

Groundbreaking Study Uncovers How Calcium Crystals in Knees Accelerate Arthritis Progression

Medriva 2/29/2024


‘Pain is normal’: The frustrating present and possible future of osteoarthritis treatment

Healio 2/27/2023

Tuhina Neogi, MD, PhD, Returns to Lead the Committee on Quality of Care

The Rheumatologist 12/12/2022

Intensive Gout Treatment Meets Urate Goal, Lowers Tophi Burden

Medscape 11/18/2022

Subcutaneous tanezumab, NSAIDs improve osteoarthritis pain

Healio 4/27/2022

'Horribly mismanaged': Debate over gout treatment rages as cases surge

Healio 2/25/2022

Colchicine as COVID-19 treatment suffers difficult year, but some hope remains

Healio 1/21/2022

Research Insights: How to Address Osteoarthritis Treatment Gaps in Women

PPM 4/10/2021

What Is the Criteria to Diagnose Rheumatoid Arthritis? What Patients Need to Know

Creaky Joints 10/15/2020

How Top Experts Are Advancing Gout Care in the United States

Renal & Urology News 9/29/2020

How to diagnose osteoarthritis and the role of imaging?

Joint Action 9/17/2020

How Top Experts Are Advancing Gout Care in the United States

Rheumatology Advisor 9/15/2020

Tuhina Neogi, MD, PhD, National Leader in Gout Management, on New ACR Guidelines

MedPage Today 9/8/2020

Coronavirus fears keep patients with severe chronic pain from seeking care

Axios 7/22/2020

Watch: The effect of the pandemic on chronic pain

AXIOS 7/14/2020

New ACR Gout Guideline Boasts Better Evidence

MedPage Today 5/12/2020

New Studies Link Opioid Prescriptions to Obesity

Pharmacy Times 4/10/2020

Opioid Prescriptions Linked to Obesity

PsychCentral 4/7/2020

Obesity Increases Likelihood of Long-term Prescription Opioid Use, Researchers Find

Philly Voice 4/6/2020

Failure of Management: Treatment Gaps at the Root of Dismal Gout Care

Healio 12/16/2019

Three Quick Tips for Managing Osteoarthritis

Medscape 12/13/2019

Health Risks of NSAIDs Led to 'Significant Under-Treatment of Pain'

Pain News Network: 12/12/2019

ACR Releases Draft Gout Guideline

The Rheumatologist 11/20/2019

ACR, Arthritis Foundation Guidelines Favor Nondrug Therapy Over TENS, Stem Cells For OA

Healio 11/15/2019

Gout Guidelines Call For Treat-to-Target Strategy Using Allopurinol

Healio 11/15/2019

ACR Previews Updated Gout Practice Guideline

Rheumatology Consultant 11/13/2019

Outgoing President Touts OARSI Legacy, Renewed Drive To ‘Build Bridges’ Internationally

Healio 5/3/2019

Omega-3 Fatty Acids From Fish May Prevent Recurrent Gout Attacks

Medical Dialogues 5/1/2019

Dietary omega-3 fatty acids linked to lower risk of recurrent gout flare

Healio 4/18/2019

Why Boston's Brightest Industry Stars Are Throwing in the Towel

Boston Magazine 4/18/2019

Gout Outcomes Better With Nurse-Led Care

Renal & Urology News 10/19/2018

Study Sees No Link Between Gout Drug, Kidney Disease

Health Day 10/8/2018

2022 Osteoarthritis Research Society International (OARSI): Clinical Research Award
2021 Lund University, Sweden: Honorary Degree: Doctor of Medicine, honoris causa
2020 Roxbury Society of Medical Information, elected member
2020 Boston University School of Medicine: Alan S. Cohen Professor of Rheumatology (endowment)
2019 National Society of Clinical Rheumatology, elected member
2016 Boston University School of Medicine: Robert Dawson Evans Research Mentoring Award
2014 American College of Rheumatology: Henry Kunkel Young Investigator
2011 Osteoarthritis Research Society International: Young Investigator Award
2009 Delta Omega Honor Society
2009 Arthritis Foundation: J.V. Satterfield Research Award
2009 Boston University School of Medicine: Robert Dawson Evans Junior Faculty Merit Award
1998 Alpha Omega Alpha Honor Medical Society
In addition to these self-described keywords below, a list of MeSH based concepts is available here.


I have had an ongoing commitment to mentoring as evidenced by the successes of my mentees in obtaining career development grants, first-authored peer-reviewed publications, and presentations at national and international meetings. These mentoring efforts are complemented by a number of formal programs available at BUSM. Further, I helped spearhead the “Train the Mentors” program for which I served on the steering committee and act as a facilitator. I also developed and led the CTSI Research Career Support Program initiative, PRIME (Pathways to Research Independence and Mentoring Excellence), which aims to support early career mentored researchers to successfully transition to becoming independent investigators.

The majority of my mentoring activities occur within the Section of Rheumatology, which comprises a multidisciplinary team of senior faculty, junior investigators and additional staff dedicated to the conduct of research (e.g., project managers, research assistants, statistical programmers). I also serve on numerous Masters and PhD thesis committees for graduate students at the BU School of Public Health.

I received the 2016 Robert Dawson Evans Research Mentoring Award.

Available to Mentor as: (Review Mentor Role Definitions):
  • Career Mentor
  • Co-Mentor or Peer Mentor
  • Project Mentor
  • Research / Scholarly Mentor
Contact for Mentoring:
  • Email (see 'Contact Info')

650 Albany St Evans Biomed Research Ctr
Boston MA 02118
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