Tuhina Neogi, MD, PhD
Professor
Boston University School of Medicine
Dept of Medicine
Rheumatology

MD, University of Toronto
PhD, Boston University School of Public Health




I am a rheumatologist and epidemiologist whose research has focused primarily on risk factors for knee osteoarthritis and gout, pain mechanisms in knee osteoarthritis, as well as methodologic issues of relevance for rheumatic diseases. I have had continuous peer-reviewed foundation and NIH funding since 2003, and have over 300 peer-reviewed publications to date. I am a past chair of the FDA Arthritis Advisory Committee, serve(d) on the boards two international societies: Osteoarthritis Research Society International (OARSI) and Gout, Hyperuricemia, and Crystal-Associated Diseases Network (G-CAN), and on committees for the American College of Rheumatology (ACR) and International Association for the Study Pain (IASP), among others. My work has been recognized with the prestigious 2014 ACR Henry Kunkel Young Investigator Award for outstanding and promising independent contributions to rheumatology research (awarded to no more than one clinical researcher and/or one basic science researcher each year), and the 2022 OARSI Clinical Research Award (in recognition of important contributions to OA research). I have also engaged in developing new classification criteria for a number of rheumatic diseases. In addition to research, clinical work, and teaching, one of my key roles is to mentor trainees and junior faculty in musculoskeletal disease-related research. To that end, I was awarded the 2016 Robert Dawson Evans Research Mentoring Award. I also developed and led the new CTSI Research Career Support Program initiative, PRIME (Pathways to Research Independence and Mentoring Excellence), which aims to support early career mentored researchers to successfully transition to becoming independent researchers.

Expertise includes:
- Osteoarthritis: epidemiology; risk factors; mechanisms of osteoarthritis-related pain; the role of bone in the pathophysiology of osteoarthritis
- Gout: epidemiology; risk factors and triggers for gout attacks; management of gout; consequences of gout and hyperuricemia
- Classification criteria and outcome measures in rheumatic diseases.
- Novel methodology to address challenging epidemiologic issues

Diversity, Equity, Inclusion and Accessibility

As Chief of Rheumatology, I have launched and supported a number of DEIA-related initiatives, including as examples: monthly Section-wide JEDI (Justice, Equity, Diversity, Inclusion) meeting involving staff, trainees, and faculty at which we address DEI topics of relevance to medicine, academia, work environment, interpersonal interactions, structural/systemic policies, etc.; a standardized and structured fellowship interview process with a DEI lens; programs focused on health equity for our patients.

At the institutional level, I serve/have served on: Women's Leadership Advisory Board, Diversity & Inclusion Advisory Council, BMC's Equity Acceleratory Research Working Group ("WG4")

COVID19-related DEI activities at BUMC:
- I am co-PI with Dr. Megan Bair-Merritt on the 2022 Doris Duke Charitable Foundation COVID-19 Fund to Retain Clinical Scientists to provide support to faculty whose research was disrupted by the adverse effects of the pandemic, compounded by caregiving responsibilities. (https://www.ddcf.org/news--insights/articles/largest-us-collaborative-funding-effort-for-equity-in-biomedicine-awards-$12.1-million-in-grants/)
- In the earliest phase of the COVID-19 pandemic, our patients at BMC were among the most affected people in the city, yet pharmaceutical companies were not bringing their clinical trials to our institution. I worked closely with a multidisciplinary group, the Clinical Trials Office, and BMC leadership to bring one of the first therapeutic trials to BMC to better serve our patients, who are often from backgrounds traditionally excluded from clinical trials. We were among the highest recruiting sites, and we had the most diversity, with >80% speaking a first-language other than English

Professor
Boston University School of Public Health
Epidemiology


Chief
Boston Medical Center
Medicine
Rheumatology

Investigator
Framingham Heart Study


Member
Boston University
Arthritis & Autoimmune Diseases Research Center


Member
Boston University
Evans Center for Interdisciplinary Biomedical Research


Section Chief of Rheumatology
Boston University School of Medicine
Medicine
Rheumatology



PRROPS: Pathways of Risk and Resilience for Overlapping Pain and Sensitization
07/15/2021 - 04/30/2026 (Multi-PI)
PI: Tuhina Neogi, MD, PhD
NIH/National Institute of Neurological Disorders & Stroke
1R01NS121419-01

Pain in community-based older African American Adults: The Jackson Heart Study
09/30/2020 - 05/31/2025 (Multi-PI)
PI: Tuhina Neogi, MD, PhD
NIH/National Institute on Aging
5R01AG066914-02

CAPSITE: Community Assessment of Pain and Sensitization in the Elderly
01/01/2020 - 11/30/2024 (Multi-PI)
PI: Tuhina Neogi, MD, PhD
NIH/National Institute on Aging
5R01AG066010-03

Group-based mindfulness for patients with chronic low back pain in the primary care setting
09/01/2020 - 08/31/2024 (Subcontract PI)
Boston Medical Center Corporation NIH NCCIH
5UH3AT010621-03

CARE (Creating and Advancing Research Equity) across BUSM
10/15/2021 - 10/14/2023 (Multi-PI)
PI: Tuhina Neogi, MD, PhD
Doris Duke Charitable Foundation John Templeton Fdn


Optimizing the value of pain management in knee osteoarthritis patients with comorbidities
08/01/2018 - 06/30/2023 (Subcontract PI)
The Brigham and Women's Hospital, Inc. NIH NIAMS
5R01AR074290-04

Wearable sensor-based Outcomes Following Physical Therapy in Knee Osteoarthritis: A Feasibility Study (WESENS-OA)
12/20/2019 - 12/31/2022 (Multi-PI)
PI: Tuhina Neogi, MD, PhD
Pfizer, Inc.


Evaluation of neuropathic-like symptoms and objective signs of neuropathy post-knee replacement in patient with knee osteoarthritis
12/01/2020 - 09/01/2022 (PI)
Rheumatology Research Foundation


The Role of Urate in Knee Osteoarthritis-Related Inflammation, Pathology and Pain
02/01/2017 - 06/30/2022 (PI)
NIH/National Institute of Arthritis & Musculoskeletal & Skin Diseases
5K24AR070892-05

Pain sensitization in a trial of physical therapy for OA and meniscal tear
09/12/2019 - 08/30/2021 (Subcontract PI)
The Brigham and Women's Hospital, Inc. NIH NIAMS
5R21AR076156-02

Showing 10 of 28 results. Show All Results

Phase 3 multicenter, randomized, double-blind, placebo-controlled study to assess the efficacy
04/27/2020 - 04/27/2023 (PI)
Novartis Pharma Corp


Title


Yr Title Project-Sub Proj Pubs
2021 Healthy knee aging vs. osteoarthritis in three large diverse cohorts: What is the clinical relevance of structural changes seen on radiographs? 1R01AR078187-01
2021 PRROPS: Pathways of Risk and Resilience for Overlapping Pain and Sensitization 1R01NS121419-01
2021 Pain in community-based older African American Adults: The Jackson Heart Study 5R01AG066914-02
2021 CAPSITE: Community Assessment of Pain and Sensitization in the Elderly 5R01AG066010-02
2021 The Role of Urate in Knee Osteoarthritis-Related Inflammation, Pathology and Pain 5K24AR070892-05 37
2020 Pain in community-based older African American Adults: The Jackson Heart Study 1R01AG066914-01A1
2020 CAPSITE: Community Assessment of Pain and Sensitization in the Elderly 1R01AG066010-01
2020 The Role of Urate in Knee Osteoarthritis-Related Inflammation, Pathology and Pain 5K24AR070892-04 37
2019 The Role of Urate in Knee Osteoarthritis-Related Inflammation, Pathology and Pain 5K24AR070892-03 37
2018 The Role of Urate in Knee Osteoarthritis-Related Inflammation, Pathology and Pain 5K24AR070892-02 37
Showing 10 of 26 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Thomas MJ, Guillemin F, Neogi T. Osteoarthritis Flares. Clin Geriatr Med. 2022 May; 38(2):239-257. PMID: 35410678
     
  2. Kiadaliri A, Neogi T, Englund M. Gout and hospital admission for ambulatory care sensitive conditions:risks and trajectories. J Rheumatol. 2022 Apr 15.View Related Profiles. PMID: 35428711
     
  3. Wallace BI, Moore MN, Heisler AC, Muhammad LN, Song J, Clauw DJ, Bingham CO, Bolster MB, Marder W, Neogi T, Wohlfahrt A, Dunlop DD, Lee YC. Fibromyalgianess and glucocorticoid persistence among patients with rheumatoid arthritis. Rheumatology (Oxford). 2022 Apr 11; 61(4):1556-1562. PMID: 34293092
     
  4. Gløersen M, Neogi T, Jafarzadeh SR, Sexton J, Haugen IK. Reply. Arthritis Rheumatol. 2022 Mar 31.View Related Profiles. PMID: 35358373
     
  5. Song J, Muhammad LN, Neogi T, Dunlop DD, Wohlfahrt A, Bolster MB, Bingham CO, Clauw DJ, Marder W, Lee YC. Pain sensitization as a potential mediator of the relationship between sleep disturbance and subsequent pain in rheumatoid arthritis. Arthritis Care Res (Hoboken). 2022 Mar 31. PMID: 35358376
     
  6. Neogi T, Hunter DJ, Churchill M, Shirinsky I, White A, Guermazi A, Omata M, Fountaine RJ, Pixton G, Viktrup L, Brown MT, West CR, Verburg KM. Observed efficacy and clinically important improvements in participants with osteoarthritis treated with subcutaneous tanezumab: results from a 56-week randomized NSAID-controlled study. Arthritis Res Ther. 2022 Mar 29; 24(1):78.View Related Profiles. PMID: 35351194; PMCID: PMC8966257; DOI: 10.1186/s13075-022-02759-0;
     
  7. Lenhard NK, Sullivan JK, Ross EL, Song S, Edwards RR, Hunter DJ, Neogi T, Katz JN, Losina E. Does Screening for Depressive Symptoms Help Optimize Duloxetine Use in Knee Osteoarthritis Patients With Moderate Pain? A Cost-Effectiveness Analysis. Arthritis Care Res (Hoboken). 2022 May; 74(5):776-789.View Related Profiles. PMID: 33253496; PMCID: PMC8164641; DOI: 10.1002/acr.24519;
     
  8. Gløersen M, Steen Pettersen P, Neogi T, Jafarzadeh SR, Vistnes M, Thudium CS, Bay-Jensen AC, Sexton J, Kvien TK, Hammer HB, Haugen IK. Associations of Body Mass Index With Pain and the Mediating Role of Inflammatory Biomarkers in People With Hand Osteoarthritis. Arthritis Rheumatol. 2022 May; 74(5):810-817.View Related Profiles. PMID: 35137553; DOI: 10.1002/art.42056;
     
  9. Helget LN, England BR, Roul P, Sayles H, Petro AD, Neogi T, O'Dell JR, Mikuls TR. Cause-Specific Mortality in Patients with Gout in the United States Veteran's Health Administration: A Matched Cohort Study. Arthritis Care Res (Hoboken). 2022 Mar 16. PMID: 35294114
     
  10. Liew JW, Peloquin C, Tedeschi SK, Felson DT, Zhang Y, Choi HK, Terkeltaub R, Neogi T. Proton Pump Inhibitors and Risk of Calcium Pyrophosphate Deposition in a Population-Based Study. Arthritis Care Res (Hoboken). 2022 Mar 04.View Related Profiles. PMID: 35245410
     
Showing 10 of 306 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 306 publications over 21 distinct years, with a maximum of 39 publications in 2021

YearPublications
19981
20031
20042
20052
20068
20071
20089
20098
201013
201115
201218
201317
201417
201517
201624
201715
201831
201920
202029
202139
202219


Recent (within 3 months)

Subcutaneous tanezumab, NSAIDs improve osteoarthritis pain

Healio 4/27/2022

Older

'Horribly mismanaged': Debate over gout treatment rages as cases surge

Healio 2/25/2022

Colchicine as COVID-19 treatment suffers difficult year, but some hope remains

Healio 1/21/2022

Research Insights: How to Address Osteoarthritis Treatment Gaps in Women

PPM 4/10/2021

What Is the Criteria to Diagnose Rheumatoid Arthritis? What Patients Need to Know

Creaky Joints 10/15/2020

How Top Experts Are Advancing Gout Care in the United States

Renal & Urology News 9/29/2020

How to diagnose osteoarthritis and the role of imaging?

Joint Action 9/17/2020

How Top Experts Are Advancing Gout Care in the United States

Rheumatology Advisor 9/15/2020

Tuhina Neogi, MD, PhD, National Leader in Gout Management, on New ACR Guidelines

MedPage Today 9/8/2020

Coronavirus fears keep patients with severe chronic pain from seeking care

Axios 7/22/2020

Watch: The effect of the pandemic on chronic pain

AXIOS 7/14/2020

New ACR Gout Guideline Boasts Better Evidence

MedPage Today 5/12/2020

New Studies Link Opioid Prescriptions to Obesity

Pharmacy Times 4/10/2020

Opioid Prescriptions Linked to Obesity

PsychCentral 4/7/2020

Obesity Increases Likelihood of Long-term Prescription Opioid Use, Researchers Find

Philly Voice 4/6/2020

Failure of Management: Treatment Gaps at the Root of Dismal Gout Care

Healio 12/16/2019

Three Quick Tips for Managing Osteoarthritis

Medscape 12/13/2019

Health Risks of NSAIDs Led to 'Significant Under-Treatment of Pain'

Pain News Network: 12/12/2019

ACR Releases Draft Gout Guideline

The Rheumatologist 11/20/2019

ACR, Arthritis Foundation Guidelines Favor Nondrug Therapy Over TENS, Stem Cells For OA

Healio 11/15/2019

Gout Guidelines Call For Treat-to-Target Strategy Using Allopurinol

Healio 11/15/2019

ACR Previews Updated Gout Practice Guideline

Rheumatology Consultant 11/13/2019

Outgoing President Touts OARSI Legacy, Renewed Drive To ‘Build Bridges’ Internationally

Healio 5/3/2019

Omega-3 Fatty Acids From Fish May Prevent Recurrent Gout Attacks

Medical Dialogues 5/1/2019

Dietary omega-3 fatty acids linked to lower risk of recurrent gout flare

Healio 4/18/2019

Why Boston's Brightest Industry Stars Are Throwing in the Towel

Boston Magazine 4/18/2019

Gout Outcomes Better With Nurse-Led Care

Renal & Urology News 10/19/2018

Study Sees No Link Between Gout Drug, Kidney Disease

Health Day 10/8/2018

2022 Osteoarthritis Research Society International (OARSI): Clinical Research Award
2021 Lund University, Sweden: Honorary Degree: Doctor of Medicine, honoris causa
2020 Roxbury Society of Medical Information, elected member
2020 Boston University School of Medicine: Alan S. Cohen Professor of Rheumatology (endowment)
2019 National Society of Clinical Rheumatology, elected member
2016 Boston University School of Medicine: Robert Dawson Evans Research Mentoring Award
2014 American College of Rheumatology: Henry Kunkel Young Investigator
2011 Osteoarthritis Research Society International: Young Investigator Award
2009 Delta Omega Honor Society
2009 Arthritis Foundation: J.V. Satterfield Research Award
2009 Boston University School of Medicine: Robert Dawson Evans Junior Faculty Merit Award
1998 Alpha Omega Alpha Honor Medical Society
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

epidemiology
gout
osteoarthritis
Spondyloarthritis

I have had an ongoing commitment to mentoring as evidenced by the successes of my mentees in obtaining career development grants, first-authored peer-reviewed publications, and presentations at national and international meetings. These mentoring efforts are complemented by a number of formal programs available at BUSM. Further, I helped spearhead the “Train the Mentors” program for which I served on the steering committee and act as a facilitator. I also developed and led the CTSI Research Career Support Program initiative, PRIME (Pathways to Research Independence and Mentoring Excellence), which aims to support early career mentored researchers to successfully transition to becoming independent investigators.

The majority of my mentoring activities occur within the Section of Rheumatology, which comprises a multidisciplinary team of senior faculty, junior investigators and additional staff dedicated to the conduct of research (e.g., project managers, research assistants, statistical programmers). I also serve on numerous Masters and PhD thesis committees for graduate students at the BU School of Public Health.

I received the 2016 Robert Dawson Evans Research Mentoring Award.


Available to Mentor as: (Review Mentor Role Definitions):
  • Career Mentor
  • Co-Mentor or Peer Mentor
  • Project Mentor
  • Research / Scholarly Mentor
Contact for Mentoring:
  • Email (see 'Contact Info')

650 Albany St Evans Biomed Research Ctr
Boston MA 02118
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