-
Leshchyk A, Xiang Q, Andersen SL, Gurinovich A, Song Z, Lee JH, Christensen K, Yashin A, Wojczynski M, Schwander K, Perls TT, Monti S, Sebastiani P. Mosaic Chromosomal Alterations and Human Longevity. J Gerontol A Biol Sci Med Sci. 2023 Aug 27; 78(9):1561-1568.View Related Profiles. PMID: 36988570; PMCID: PMC10460554; DOI: 10.1093/gerona/glad095;
-
Milman S, Barzilai N, Wilson KA, Van der Willik O, Lederman S, Perls T, Gao T, Leahy AM, Jain P, Montgomery A, Shuldiner AR. SuperAger Initiative: unlocking the genetic potential of exceptional longevity. Nat Aging. 2023 Jun; 3(6):627-628. PMID: 37202472
-
Karagiannis TT, Dowrey TW, Villacorta-Martin C, Montano M, Reed E, Belkina AC, Andersen SL, Perls TT, Monti S, Murphy GJ, Sebastiani P. Multi-modal profiling of peripheral blood cells across the human lifespan reveals distinct immune cell signatures of aging and longevity. EBioMedicine. 2023 Apr; 90:104514.View Related Profiles. PMID: 37005201; PMCID: PMC10114155; DOI: 10.1016/j.ebiom.2023.104514;
-
Leshchyk A, Xiang Q, Andersen SL, Gurinovich A, Song Z, Lee JH, Christensen K, Yashin A, Wojczynski M, Schwander K, Perls TT, Monti S, Sebastiani P. Mosaic chromosomal alterations and human longevity. J Gerontol A Biol Sci Med Sci. 2023 Mar 29.View Related Profiles. PMID: 36988570; PMCID: PMC10460554; DOI: 10.1093/gerona/glad095;
-
Perls T. Successful aging and its subtypes in centenarians: The Chinese experience. J Am Geriatr Soc. 2023 May; 71(5):1362-1364. PMID: 36810715; PMCID: PMC10175185; DOI: 10.1111/jgs.18282;
-
Song Z, Gurinovich A, Nygaard M, Mengel-From J, Andersen S, Cosentino S, Schupf N, Lee J, Zmuda J, Ukraintseva S, Arbeev K, Christensen K, Perls T, Sebastiani P. Rare genetic variants correlate with better processing speed. Neurobiol Aging. 2023 May; 125:115-122.View Related Profiles. PMID: 36813607; PMCID: PMC10038891; DOI: 10.1016/j.neurobiolaging.2022.11.018;
-
Xiang Q, Andersen SL, Sweigart B, Gunn S, Nygaard M, Perls TT, Sebastiani P. Signatures of Neuropsychological Test Results in the Long Life Family Study: A Cluster Analysis. J Alzheimers Dis. 2023; 93(4):1457-1469.View Related Profiles. PMID: 37212095; PMCID: PMC10635779; DOI: 10.3233/JAD-221025;
-
Bae H, Gurinovich A, Karagiannis TT, Song Z, Leshchyk A, Li M, Andersen SL, Arbeev K, Yashin A, Zmuda J, An P, Feitosa M, Giuliani C, Franceschi C, Garagnani P, Mengel-From J, Atzmon G, Barzilai N, Puca A, Schork NJ, Perls TT, Sebastiani P. A Genome-Wide Association Study of 2304 Extreme Longevity Cases Identifies Novel Longevity Variants. Int J Mol Sci. 2022 Dec 21; 24(1).View Related Profiles. PMID: 36613555; PMCID: PMC9820206; DOI: 10.3390/ijms24010116;
-
Gurinovich A, Li M, Leshchyk A, Bae H, Song Z, Arbeev KG, Nygaard M, Feitosa MF, Perls TT, Sebastiani P. Evaluation of GENESIS, SAIGE, REGENIE and fastGWA-GLMM for genome-wide association studies of binary traits in correlated data. Front Genet. 2022; 13:897210.View Related Profiles. PMID: 36212134; PMCID: PMC9544087; DOI: 10.3389/fgene.2022.897210;
-
Sebastiani P, Song Z, Ellis D, Tian Q, Schwaiger-Haber M, Stancliffe E, Lustgarten MS, Funk CC, Baloni P, Yao CH, Joshi S, Marron MM, Gurinovich A, Li M, Leshchyk A, Xiang Q, Andersen SL, Feitosa MF, Ukraintseva S, Soerensen M, Fiehn O, Ordovas JM, Haigis M, Monti S, Barzilai N, Milman S, Ferrucci L, Rappaport N, Patti GJ, Perls TT. A metabolomic signature of the APOE2 allele. Geroscience. 2023 Feb; 45(1):415-426.View Related Profiles. PMID: 35997888; PMCID: PMC9886693; DOI: 10.1007/s11357-022-00646-9;
-
-
Wojczynski MK, Jiuan Lin S, Sebastiani P, Perls TT, Lee J, Kulminski A, Newman A, Zmuda JM, Christensen K, Province MA. NIA Long Life Family Study: Objectives, Design, and Heritability of Cross-Sectional and Longitudinal Phenotypes. J Gerontol A Biol Sci Med Sci. 2022 Apr 01; 77(4):717-727.View Related Profiles. PMID: 34739053; PMCID: PMC8974329; DOI: 10.1093/gerona/glab333;
-
-
Gunn S, Wainberg M, Song Z, Andersen S, Boudreau R, Feitosa MF, Tan Q, Montasser ME, O'Connell JR, Stitziel N, Price N, Perls T, Schork NJ, Sebastiani P. Distribution of 54 polygenic risk scores for common diseases in long lived individuals and their offspring. Geroscience. 2022 Apr; 44(2):719-729.View Related Profiles. PMID: 35119614; PMCID: PMC9135909; DOI: 10.1007/s11357-022-00518-2;
-
Gurinovich A, Song Z, Zhang W, Federico A, Monti S, Andersen SL, Jennings LL, Glass DJ, Barzilai N, Millman S, Perls TT, Sebastiani P. Correction to: Effect of longevity genetic variants on the molecular aging rate. Geroscience. 2021 Aug; 43(4):2101.View Related Profiles. PMID: 34143375; PMCID: PMC8492867; DOI: 10.1007/s11357-021-00400-7;
-
Renner SW, Qiao Y, Gmelin T, Santanasto AJ, Boudreau RM, Walston JD, Perls TT, Christensen K, Newman AB, Glynn NW. Association of fatigue, inflammation, and physical activity on gait speed: the Long Life Family Study. Aging Clin Exp Res. 2022 Feb; 34(2):367-374. PMID: 34196949; PMCID: PMC8864668; DOI: 10.1007/s40520-021-01923-x;
-
Gurinovich A, Song Z, Zhang W, Federico A, Monti S, Andersen SL, Jennings LL, Glass DJ, Barzilai N, Millman S, Perls TT, Sebastiani P. Effect of longevity genetic variants on the molecular aging rate. Geroscience. 2021 06; 43(3):1237-1251.View Related Profiles. PMID: 33948810; PMCID: PMC8190315; DOI: 10.1007/s11357-021-00376-4;
-
-
Deelen J, Evans DS, Arking DE, Tesi N, Nygaard M, Liu X, Wojczynski MK, Biggs ML, van der Spek A, Atzmon G, Ware EB, Sarnowski C, Smith AV, Seppälä I, Cordell HJ, Dose J, Amin N, Arnold AM, Ayers KL, Barzilai N, Becker EJ, Beekman M, Blanché H, Christensen K, Christiansen L, Collerton JC, Cubaynes S, Cummings SR, Davies K, Debrabant B, Deleuze JF, Duncan R, Faul JD, Franceschi C, Galan P, Gudnason V, Harris TB, Huisman M, Hurme MA, Jagger C, Jansen I, Jylhä M, Kähönen M, Karasik D, Kardia SLR, Kingston A, Kirkwood TBL, Launer LJ, Lehtimäki T, Lieb W, Lyytikäinen LP, Martin-Ruiz C, Min J, Nebel A, Newman AB, Nie C, Nohr EA, Orwoll ES, Perls TT, Province MA, Psaty BM, Raitakari OT, Reinders MJT, Robine JM, Rotter JI, Sebastiani P, Smith J, Sørensen TIA, Taylor KD, Uitterlinden AG, van der Flier W, van der Lee SJ, van Duijn CM, van Heemst D, Vaupel JW, Weir D, Ye K, Zeng Y, Zheng W, Holstege H, Kiel DP, Lunetta KL, Slagboom PE, Murabito JM. Publisher Correction: A meta-analysis of genome-wide association studies identifies multiple longevity genes. Nat Commun. 2021 Apr 23; 12(1):2463.View Related Profiles. PMID: 33893282; PMCID: PMC8065049; DOI: 10.1038/s41467-021-22613-2;
-
Feitosa MF, Kuipers AL, Wojczynski MK, Wang L, Barinas-Mitchell E, Kulminski AM, Thyagarajan B, Lee JH, Perls T, Christensen K, Newman AB, Zmuda JM, Province MA. Heterogeneity of the Predictive Polygenic Risk Scores for Coronary Heart Disease Age-at-Onset in Three Different Coronary Heart Disease Family-Based Ascertainments. Circ Genom Precis Med. 2021 06; 14(3):e003201. PMID: 33844929; PMCID: PMC8214825; DOI: 10.1161/CIRCGEN.120.003201;
-
Sebastiani P, Federico A, Morris M, Gurinovich A, Tanaka T, Chandler KB, Andersen SL, Denis G, Costello CE, Ferrucci L, Jennings L, Glass DJ, Monti S, Perls TT. Protein signatures of centenarians and their offspring suggest centenarians age slower than other humans. Aging Cell. 2021 02; 20(2):e13290.View Related Profiles. PMID: 33512769; PMCID: PMC7884029; DOI: 10.1111/acel.13290;
-
-
Perls TT. Cognitive Trajectories and Resilience in Centenarians-Findings From the 100-Plus Study. JAMA Netw Open. 2021 01 04; 4(1):e2032538. PMID: 33449091
-
-
Andersen SL, Sweigart B, Glynn NW, Wojczynski MK, Thyagarajan B, Mengel-From J, Thielke S, Perls TT, Libon DJ, Au R, Cosentino S, Sebastiani P. Digital Technology Differentiates Graphomotor and Information Processing Speed Patterns of Behavior. J Alzheimers Dis. 2021; 82(1):17-32.View Related Profiles. PMID: 34219735; PMCID: PMC8328075; DOI: 10.3233/JAD-201119;
-
Du M, Andersen SL, Schupf N, Feitosa MF, Barker MS, Perls TT, Sebastiani P. Association Between APOE Alleles and Change of Neuropsychological Tests in the Long Life Family Study. J Alzheimers Dis. 2021; 79(1):117-125.View Related Profiles. PMID: 33216038; PMCID: PMC7952213; DOI: 10.3233/JAD-201113;
-
Lau-Ng R, Caruso LB, Perls TT. Reply to Comment on COVID-19 Deaths in Long Term Care Facilities - A Critical Piece of the Puzzle. J Am Geriatr Soc. 2020 12; 68(12):2748.View Related Profiles. PMID: 32835433
-
-
-
de Las Fuentes L, Sung YJ, Noordam R, Winkler T, Feitosa MF, Schwander K, Bentley AR, Brown MR, Guo X, Manning A, Chasman DI, Aschard H, Bartz TM, Bielak LF, Campbell A, Cheng CY, Dorajoo R, Hartwig FP, Horimoto ARVR, Li C, Li-Gao R, Liu Y, Marten J, Musani SK, Ntalla I, Rankinen T, Richard M, Sim X, Smith AV, Tajuddin SM, Tayo BO, Vojinovic D, Warren HR, Xuan D, Alver M, Boissel M, Chai JF, Chen X, Christensen K, Divers J, Evangelou E, Gao C, Girotto G, Harris SE, He M, Hsu FC, Kühnel B, Laguzzi F, Li X, Lyytikäinen LP, Nolte IM, Poveda A, Rauramaa R, Riaz M, Rueedi R, Shu XO, Snieder H, Sofer T, Takeuchi F, Verweij N, Ware EB, Weiss S, Yanek LR, Amin N, Arking DE, Arnett DK, Bergmann S, Boerwinkle E, Brody JA, Broeckel U, Brumat M, Burke G, Cabrera CP, Canouil M, Chee ML, Chen YI, Cocca M, Connell J, de Silva HJ, de Vries PS, Eiriksdottir G, Faul JD, Fisher V, Forrester T, Fox EF, Friedlander Y, Gao H, Gigante B, Giulianini F, Gu CC, Gu D, Harris TB, He J, Heikkinen S, Heng CK, Hunt S, Ikram MA, Irvin MR, Kähönen M, Kavousi M, Khor CC, Kilpeläinen TO, Koh WP, Komulainen P, Kraja AT, Krieger JE, Langefeld CD, Li Y, Liang J, Liewald DCM, Liu CT, Liu J, Lohman KK, Mägi R, McKenzie CA, Meitinger T, Metspalu A, Milaneschi Y, Milani L, Mook-Kanamori DO, Nalls MA, Nelson CP, Norris JM, O'Connell J, Ogunniyi A, Padmanabhan S, Palmer ND, Pedersen NL, Perls T, Peters A, Petersmann A, Peyser PA, Polasek O, Porteous DJ, Raffel LJ, Rice TK, Rotter JI, Rudan I, Rueda-Ochoa OL, Sabanayagam C, Salako BL, Schreiner PJ, Shikany JM, Sidney SS, Sims M, Sitlani CM, Smith JA, Starr JM, Strauch K, Swertz MA, Teumer A, Tham YC, Uitterlinden AG, Vaidya D, van der Ende MY, Waldenberger M, Wang L, Wang YX, Wei WB, Weir DR, Wen W, Yao J, Yu B, Yu C, Yuan JM, Zhao W, Zonderman AB, Becker DM, Bowden DW, Deary IJ, Dörr M, Esko T, Freedman BI, Froguel P, Gasparini P, Gieger C, Jonas JB, Kammerer CM, Kato N, Lakka TA, Leander K, Lehtimäki T, Magnusson PKE, Marques-Vidal P, Penninx BWJH, Samani NJ, van der Harst P, Wagenknecht LE, Wu T, Zheng W, Zhu X, Bouchard C, Cooper RS, Correa A, Evans MK, Gudnason V, Hayward C, Horta BL, Kelly TN, Kritchevsky SB, Levy D, Palmas WR, Pereira AC, Province MM, Psaty BM, Ridker PM, Rotimi CN, Tai ES, van Dam RM, van Duijn CM, Wong TY, Rice K, Gauderman WJ, Morrison AC, North KE, Kardia SLR, Caulfield MJ, Elliott P, Munroe PB, Franks PW, Rao DC, Fornage M. Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci. Mol Psychiatry. 2021 06; 26(6):2111-2125.View Related Profiles. PMID: 32372009; PMCID: PMC7641978; DOI: 10.1038/s41380-020-0719-3;
-
-
-
Perls TT, Tan EJ. Healthy Longevity: An Introduction to the Special Issue. J Gerontol A Biol Sci Med Sci. 2019 11 13; 74(Suppl_1):S1-S3. PMID: 31724053
-
Tin A, Marten J, Halperin Kuhns VL, Li Y, Wuttke M, Kirsten H, Sieber KB, Qiu C, Gorski M, Yu Z, Giri A, Sveinbjornsson G, Li M, Chu AY, Hoppmann A, O'Connor LJ, Prins B, Nutile T, Noce D, Akiyama M, Cocca M, Ghasemi S, van der Most PJ, Horn K, Xu Y, Fuchsberger C, Sedaghat S, Afaq S, Amin N, Ärnlöv J, Bakker SJL, Bansal N, Baptista D, Bergmann S, Biggs ML, Biino G, Boerwinkle E, Bottinger EP, Boutin TS, Brumat M, Burkhardt R, Campana E, Campbell A, Campbell H, Carroll RJ, Catamo E, Chambers JC, Ciullo M, Concas MP, Coresh J, Corre T, Cusi D, Felicita SC, de Borst MH, De Grandi A, de Mutsert R, de Vries APJ, Delgado G, Demirkan A, Devuyst O, Dittrich K, Eckardt KU, Ehret G, Endlich K, Evans MK, Gansevoort RT, Gasparini P, Giedraitis V, Gieger C, Girotto G, Gögele M, Gordon SD, Gudbjartsson DF, Gudnason V, Haller T, Hamet P, Harris TB, Hayward C, Hicks AA, Hofer E, Holm H, Huang W, Hutri-Kähönen N, Hwang SJ, Ikram MA, Lewis RM, Ingelsson E, Jakobsdottir J, Jonsdottir I, Jonsson H, Joshi PK, Josyula NS, Jung B, Kähönen M, Kamatani Y, Kanai M, Kerr SM, Kiess W, Kleber ME, Koenig W, Kooner JS, Körner A, Kovacs P, Krämer BK, Kronenberg F, Kubo M, Kühnel B, La Bianca M, Lange LA, Lehne B, Lehtimäki T, Liu J, Loeffler M, Loos RJF, Lyytikäinen LP, Magi R, Mahajan A, Martin NG, März W, Mascalzoni D, Matsuda K, Meisinger C, Meitinger T, Metspalu A, Milaneschi Y, O'Donnell CJ, Wilson OD, Gaziano JM, Mishra PP, Mohlke KL, Mononen N, Montgomery GW, Mook-Kanamori DO, Müller-Nurasyid M, Nadkarni GN, Nalls MA, Nauck M, Nikus K, Ning B, Nolte IM, Noordam R, O'Connell JR, Olafsson I, Padmanabhan S, Penninx BWJH, Perls T, Peters A, Pirastu M, Pirastu N, Pistis G, Polasek O, Ponte B, Porteous DJ, Poulain T, Preuss MH, Rabelink TJ, Raffield LM, Raitakari OT, Rettig R, Rheinberger M, Rice KM, Rizzi F, Robino A, Rudan I, Krajcoviechova A, Cifkova R, Rueedi R, Ruggiero D, Ryan KA, Saba Y, Salvi E, Schmidt H, Schmidt R, Shaffer CM, Smith AV, Smith BH, Spracklen CN, Strauch K, Stumvoll M, Sulem P, Tajuddin SM, Teren A, Thiery J, Thio CHL, Thorsteinsdottir U, Toniolo D, Tönjes A, Tremblay J, Uitterlinden AG, Vaccargiu S, van der Harst P, van Duijn CM, Verweij N, Völker U, Vollenweider P, Waeber G, Waldenberger M, Whitfield JB, Wild SH, Wilson JF, Yang Q, Zhang W, Zonderman AB, Bochud M, Wilson JG, Pendergrass SA, Ho K, Parsa A, Pramstaller PP, Psaty BM, Böger CA, Snieder H, Butterworth AS, Okada Y, Edwards TL, Stefansson K, Susztak K, Scholz M, Heid IM, Hung AM, Teumer A, Pattaro C, Woodward OM, Vitart V, Köttgen A. Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels. Nat Genet. 2019 10; 51(10):1459-1474.View Related Profiles. PMID: 31578528; PMCID: PMC6858555; DOI: 10.1038/s41588-019-0504-x;
-
-
-
Deelen J, Evans DS, Arking DE, Tesi N, Nygaard M, Liu X, Wojczynski MK, Biggs ML, van der Spek A, Atzmon G, Ware EB, Sarnowski C, Smith AV, Seppälä I, Cordell HJ, Dose J, Amin N, Arnold AM, Ayers KL, Barzilai N, Becker EJ, Beekman M, Blanché H, Christensen K, Christiansen L, Collerton JC, Cubaynes S, Cummings SR, Davies K, Debrabant B, Deleuze JF, Duncan R, Faul JD, Franceschi C, Galan P, Gudnason V, Harris TB, Huisman M, Hurme MA, Jagger C, Jansen I, Jylhä M, Kähönen M, Karasik D, Kardia SLR, Kingston A, Kirkwood TBL, Launer LJ, Lehtimäki T, Lieb W, Lyytikäinen LP, Martin-Ruiz C, Min J, Nebel A, Newman AB, Nie C, Nohr EA, Orwoll ES, Perls TT, Province MA, Psaty BM, Raitakari OT, Reinders MJT, Robine JM, Rotter JI, Sebastiani P, Smith J, Sørensen TIA, Taylor KD, Uitterlinden AG, van der Flier W, van der Lee SJ, van Duijn CM, van Heemst D, Vaupel JW, Weir D, Ye K, Zeng Y, Zheng W, Holstege H, Kiel DP, Lunetta KL, Slagboom PE, Murabito JM. A meta-analysis of genome-wide association studies identifies multiple longevity genes. Nat Commun. 2019 08 14; 10(1):3669.View Related Profiles. PMID: 31413261; PMCID: PMC6694136; DOI: 10.1038/s41467-019-11558-2;
-
Sebastiani P, Monti S, Morris M, Gurinovich A, Toshiko T, Andersen SL, Sweigart B, Ferrucci L, Jennings LL, Glass DJ, Perls TT. A serum protein signature of APOE genotypes in centenarians. Aging Cell. 2019 12; 18(6):e13023.View Related Profiles. PMID: 31385390; PMCID: PMC6826130; DOI: 10.1111/acel.13023;
-
Sung YJ, de Las Fuentes L, Winkler TW, Chasman DI, Bentley AR, Kraja AT, Ntalla I, Warren HR, Guo X, Schwander K, Manning AK, Brown MR, Aschard H, Feitosa MF, Franceschini N, Lu Y, Cheng CY, Sim X, Vojinovic D, Marten J, Musani SK, Kilpeläinen TO, Richard MA, Aslibekyan S, Bartz TM, Dorajoo R, Li C, Liu Y, Rankinen T, Smith AV, Tajuddin SM, Tayo BO, Zhao W, Zhou Y, Matoba N, Sofer T, Alver M, Amini M, Boissel M, Chai JF, Chen X, Divers J, Gandin I, Gao C, Giulianini F, Goel A, Harris SE, Hartwig FP, He M, Horimoto ARVR, Hsu FC, Jackson AU, Kammerer CM, Kasturiratne A, Komulainen P, Kühnel B, Leander K, Lee WJ, Lin KH, Luan J, Lyytikäinen LP, McKenzie CA, Nelson CP, Noordam R, Scott RA, Sheu WHH, Stancáková A, Takeuchi F, van der Most PJ, Varga TV, Waken RJ, Wang H, Wang Y, Ware EB, Weiss S, Wen W, Yanek LR, Zhang W, Zhao JH, Afaq S, Alfred T, Amin N, Arking DE, Aung T, Barr RG, Bielak LF, Boerwinkle E, Bottinger EP, Braund PS, Brody JA, Broeckel U, Cade B, Campbell A, Canouil M, Chakravarti A, Cocca M, Collins FS, Connell JM, de Mutsert R, de Silva HJ, Dörr M, Duan Q, Eaton CB, Ehret G, Evangelou E, Faul JD, Forouhi NG, Franco OH, Friedlander Y, Gao H, Gigante B, Gu CC, Gupta P, Hagenaars SP, Harris TB, He J, Heikkinen S, Heng CK, Hofman A, Howard BV, Hunt SC, Irvin MR, Jia Y, Katsuya T, Kaufman J, Kerrison ND, Khor CC, Koh WP, Koistinen HA, Kooperberg CB, Krieger JE, Kubo M, Kutalik Z, Kuusisto J, Lakka TA, Langefeld CD, Langenberg C, Launer LJ, Lee JH, Lehne B, Levy D, Lewis CE, Li Y, Lim SH, Liu CT, Liu J, Liu J, Liu Y, Loh M, Lohman KK, Louie T, Mägi R, Matsuda K, Meitinger T, Metspalu A, Milani L, Momozawa Y, Mosley TH, Nalls MA, Nasri U, O'Connell JR, Ogunniyi A, Palmas WR, Palmer ND, Pankow JS, Pedersen NL, Peters A, Peyser PA, Polasek O, Porteous D, Raitakari OT, Renström F, Rice TK, Ridker PM, Robino A, Robinson JG, Rose LM, Rudan I, Sabanayagam C, Salako BL, Sandow K, Schmidt CO, Schreiner PJ, Scott WR, Sever P, Sims M, Sitlani CM, Smith BH, Smith JA, Snieder H, Starr JM, Strauch K, Tang H, Taylor KD, Teo YY, Tham YC, Uitterlinden AG, Waldenberger M, Wang L, Wang YX, Wei WB, Wilson G, Wojczynski MK, Xiang YB, Yao J, Yuan JM, Zonderman AB, Becker DM, Boehnke M, Bowden DW, Chambers JC, Chen YI, Weir DR, de Faire U, Deary IJ, Esko T, Farrall M, Forrester T, Freedman BI, Froguel P, Gasparini P, Gieger C, Horta BL, Hung YJ, Jonas JB, Kato N, Kooner JS, Laakso M, Lehtimäki T, Liang KW, Magnusson PKE, Oldehinkel AJ, Pereira AC, Perls T, Rauramaa R, Redline S, Rettig R, Samani NJ, Scott J, Shu XO, van der Harst P, Wagenknecht LE, Wareham NJ, Watkins H, Wickremasinghe AR, Wu T, Kamatani Y, Laurie CC, Bouchard C, Cooper RS, Evans MK, Gudnason V, Hixson J, Kardia SLR, Kritchevsky SB, Psaty BM, van Dam RM, Arnett DK, Mook-Kanamori DO, Fornage M, Fox ER, Hayward C, van Duijn CM, Tai ES, Wong TY, Loos RJF, Reiner AP, Rotimi CN, Bierut LJ, Zhu X, Cupples LA, Province MA, Rotter JI, Franks PW, Rice K, Elliott P, Caulfield MJ, Gauderman WJ, Munroe PB, Rao DC, Morrison AC. A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure. Hum Mol Genet. 2019 08 01; 28(15):2615-2633.View Related Profiles. PMID: 31127295; PMCID: PMC6644157; DOI: 10.1093/hmg/ddz070;
-
Marron MM, Wojczynski MK, Minster RL, Boudreau RM, Sebastiani P, Cosentino S, Thyagarajan B, Ukraintseva SV, Schupf N, Christensen K, Feitosa M, Perls T, Zmuda JM, Newman AB. Heterogeneity of healthy aging: comparing long-lived families across five healthy aging phenotypes of blood pressure, memory, pulmonary function, grip strength, and metabolism. Geroscience. 2019 08; 41(4):383-393.View Related Profiles. PMID: 31332674; PMCID: PMC6815318; DOI: 10.1007/s11357-019-00086-y;
-
Wuttke M, Li Y, Li M, Sieber KB, Feitosa MF, Gorski M, Tin A, Wang L, Chu AY, Hoppmann A, Kirsten H, Giri A, Chai JF, Sveinbjornsson G, Tayo BO, Nutile T, Fuchsberger C, Marten J, Cocca M, Ghasemi S, Xu Y, Horn K, Noce D, van der Most PJ, Sedaghat S, Yu Z, Akiyama M, Afaq S, Ahluwalia TS, Almgren P, Amin N, Ärnlöv J, Bakker SJL, Bansal N, Baptista D, Bergmann S, Biggs ML, Biino G, Boehnke M, Boerwinkle E, Boissel M, Bottinger EP, Boutin TS, Brenner H, Brumat M, Burkhardt R, Butterworth AS, Campana E, Campbell A, Campbell H, Canouil M, Carroll RJ, Catamo E, Chambers JC, Chee ML, Chee ML, Chen X, Cheng CY, Cheng Y, Christensen K, Cifkova R, Ciullo M, Concas MP, Cook JP, Coresh J, Corre T, Sala CF, Cusi D, Danesh J, Daw EW, de Borst MH, De Grandi A, de Mutsert R, de Vries APJ, Degenhardt F, Delgado G, Demirkan A, Di Angelantonio E, Dittrich K, Divers J, Dorajoo R, Eckardt KU, Ehret G, Elliott P, Endlich K, Evans MK, Felix JF, Foo VHX, Franco OH, Franke A, Freedman BI, Freitag-Wolf S, Friedlander Y, Froguel P, Gansevoort RT, Gao H, Gasparini P, Gaziano JM, Giedraitis V, Gieger C, Girotto G, Giulianini F, Gögele M, Gordon SD, Gudbjartsson DF, Gudnason V, Haller T, Hamet P, Harris TB, Hartman CA, Hayward C, Hellwege JN, Heng CK, Hicks AA, Hofer E, Huang W, Hutri-Kähönen N, Hwang SJ, Ikram MA, Indridason OS, Ingelsson E, Ising M, Jaddoe VWV, Jakobsdottir J, Jonas JB, Joshi PK, Josyula NS, Jung B, Kähönen M, Kamatani Y, Kammerer CM, Kanai M, Kastarinen M, Kerr SM, Khor CC, Kiess W, Kleber ME, Koenig W, Kooner JS, Körner A, Kovacs P, Kraja AT, Krajcoviechova A, Kramer H, Krämer BK, Kronenberg F, Kubo M, Kühnel B, Kuokkanen M, Kuusisto J, La Bianca M, Laakso M, Lange LA, Langefeld CD, Lee JJ, Lehne B, Lehtimäki T, Lieb W, Lim SC, Lind L, Lindgren CM, Liu J, Liu J, Loeffler M, Loos RJF, Lucae S, Lukas MA, Lyytikäinen LP, Mägi R, Magnusson PKE, Mahajan A, Martin NG, Martins J, März W, Mascalzoni D, Matsuda K, Meisinger C, Meitinger T, Melander O, Metspalu A, Mikaelsdottir EK, Milaneschi Y, Miliku K, Mishra PP, Mohlke KL, Mononen N, Montgomery GW, Mook-Kanamori DO, Mychaleckyj JC, Nadkarni GN, Nalls MA, Nauck M, Nikus K, Ning B, Nolte IM, Noordam R, O'Connell J, O'Donoghue ML, Olafsson I, Oldehinkel AJ, Orho-Melander M, Ouwehand WH, Padmanabhan S, Palmer ND, Palsson R, Penninx BWJH, Perls T, Perola M, Pirastu M, Pirastu N, Pistis G, Podgornaia AI, Polasek O, Ponte B, Porteous DJ, Poulain T, Pramstaller PP, Preuss MH, Prins BP, Province MA, Rabelink TJ, Raffield LM, Raitakari OT, Reilly DF, Rettig R, Rheinberger M, Rice KM, Ridker PM, Rivadeneira F, Rizzi F, Roberts DJ, Robino A, Rossing P, Rudan I, Rueedi R, Ruggiero D, Ryan KA, Saba Y, Sabanayagam C, Salomaa V, Salvi E, Saum KU, Schmidt H, Schmidt R, Schöttker B, Schulz CA, Schupf N, Shaffer CM, Shi Y, Smith AV, Smith BH, Soranzo N, Spracklen CN, Strauch K, Stringham HM, Stumvoll M, Svensson PO, Szymczak S, Tai ES, Tajuddin SM, Tan NYQ, Taylor KD, Teren A, Tham YC, Thiery J, Thio CHL, Thomsen H, Thorleifsson G, Toniolo D, Tönjes A, Tremblay J, Tzoulaki I, Uitterlinden AG, Vaccargiu S, van Dam RM, van der Harst P, van Duijn CM, Velez Edward DR, Verweij N, Vogelezang S, Völker U, Vollenweider P, Waeber G, Waldenberger M, Wallentin L, Wang YX, Wang C, Waterworth DM, Bin Wei W, White H, Whitfield JB, Wild SH, Wilson JF, Wojczynski MK, Wong C, Wong TY, Xu L, Yang Q, Yasuda M, Yerges-Armstrong LM, Zhang W, Zonderman AB, Rotter JI, Bochud M, Psaty BM, Vitart V, Wilson JG, Dehghan A, Parsa A, Chasman DI, Ho K, Morris AP, Devuyst O, Akilesh S, Pendergrass SA, Sim X, Böger CA, Okada Y, Edwards TL, Snieder H, Stefansson K, Hung AM, Heid IM, Scholz M, Teumer A, Köttgen A, Pattaro C. A catalog of genetic loci associated with kidney function from analyses of a million individuals. Nat Genet. 2019 06; 51(6):957-972.View Related Profiles. PMID: 31152163; PMCID: PMC6698888; DOI: 10.1038/s41588-019-0407-x;
-
Sebastiani P, Gurinovich A, Nygaard M, Sasaki T, Sweigart B, Bae H, Andersen SL, Villa F, Atzmon G, Christensen K, Arai Y, Barzilai N, Puca A, Christiansen L, Hirose N, Perls TT. APOE Alleles and Extreme Human Longevity. J Gerontol A Biol Sci Med Sci. 2019 01 01; 74(1):44-51.View Related Profiles. PMID: 30060062; PMCID: PMC6298189; DOI: 10.1093/gerona/gly174;
-
-
Kraja AT, Liu C, Fetterman JL, Graff M, Have CT, Gu C, Yanek LR, Feitosa MF, Arking DE, Chasman DI, Young K, Ligthart S, Hill WD, Weiss S, Luan J, Giulianini F, Li-Gao R, Hartwig FP, Lin SJ, Wang L, Richardson TG, Yao J, Fernandez EP, Ghanbari M, Wojczynski MK, Lee WJ, Argos M, Armasu SM, Barve RA, Ryan KA, An P, Baranski TJ, Bielinski SJ, Bowden DW, Broeckel U, Christensen K, Chu AY, Corley J, Cox SR, Uitterlinden AG, Rivadeneira F, Cropp CD, Daw EW, van Heemst D, de Las Fuentes L, Gao H, Tzoulaki I, Ahluwalia TS, de Mutsert R, Emery LS, Erzurumluoglu AM, Perry JA, Fu M, Forouhi NG, Gu Z, Hai Y, Harris SE, Hemani G, Hunt SC, Irvin MR, Jonsson AE, Justice AE, Kerrison ND, Larson NB, Lin KH, Love-Gregory LD, Mathias RA, Lee JH, Nauck M, Noordam R, Ong KK, Pankow J, Patki A, Pattie A, Petersmann A, Qi Q, Ribel-Madsen R, Rohde R, Sandow K, Schnurr TM, Sofer T, Starr JM, Taylor AM, Teumer A, Timpson NJ, de Haan HG, Wang Y, Weeke PE, Williams C, Wu H, Yang W, Zeng D, Witte DR, Weir BS, Wareham NJ, Vestergaard H, Turner ST, Torp-Pedersen C, Stergiakouli E, Sheu WH, Rosendaal FR, Ikram MA, Franco OH, Ridker PM, Perls TT, Pedersen O, Nohr EA, Newman AB, Linneberg A, Langenberg C, Kilpeläinen TO, Kardia SLR, Jørgensen ME, Jørgensen T, Sørensen TIA, Homuth G, Hansen T, Goodarzi MO, Deary IJ, Christensen C, Chen YI, Chakravarti A, Brandslund I, Bonnelykke K, Taylor KD, Wilson JG, Rodriguez S, Davies G, Horta BL, Thyagarajan B, Rao DC, Grarup N, Davila-Roman VG, Hudson G, Guo X, Arnett DK, Hayward C, Vaidya D, Mook-Kanamori DO, Tiwari HK, Levy D, Loos RJF, Dehghan A, Elliott P, Malik AN, Scott RA, Becker DM, de Andrade M, Province MA, Meigs JB, Rotter JI, North KE. Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits. Am J Hum Genet. 2019 01 03; 104(1):112-138.View Related Profiles. PMID: 30595373; PMCID: PMC6323610; DOI: 10.1016/j.ajhg.2018.12.001;
-
Yashin AI, Arbeev KG, Wu D, Arbeeva LS, Bagley O, Stallard E, Kulminski AM, Akushevich I, Fang F, Wojczynski MK, Christensen K, Newman AB, Boudreau RM, Province MA, Thielke S, Perls TT, An P, Elo I, Ukraintseva SV. Genetics of Human Longevity From Incomplete Data: New Findings From the Long Life Family Study. J Gerontol A Biol Sci Med Sci. 2018 10 08; 73(11):1472-1481. PMID: 30299504; PMCID: PMC6175028; DOI: 10.1093/gerona/gly057;
-
Bae H, Gurinovich A, Malovini A, Atzmon G, Andersen SL, Villa F, Barzilai N, Puca A, Perls TT, Sebastiani P. Effects of FOXO3 Polymorphisms on Survival to Extreme Longevity in Four Centenarian Studies. J Gerontol A Biol Sci Med Sci. 2018 10 08; 73(11):1439-1447.View Related Profiles. PMID: 28977569; PMCID: PMC6175020; DOI: 10.1093/gerona/glx124;
-
-
Zeng Y, Nie C, Min J, Chen H, Liu X, Ye R, Chen Z, Bai C, Xie E, Yin Z, Lv Y, Lu J, Li J, Ni T, Bolund L, Land KC, Yashin A, O'Rand AM, Sun L, Yang Z, Tao W, Gurinovich A, Franceschi C, Xie J, Gu J, Hou Y, Liu X, Xu X, Robine JM, Deelen J, Sebastiani P, Slagboom E, Perls T, Hauser E, Gottschalk W, Tan Q, Christensen K, Shi X, Lutz M, Tian XL, Yang H, Vaupel J. Sex Differences in Genetic Associations With Longevity. JAMA Netw Open. 2018 Aug; 1(4).View Related Profiles. PMID: 30294719; PMCID: PMC6173523; DOI: 10.1001/jamanetworkopen.2018.1670;
-
Feitosa MF, Kraja AT, Chasman DI, Sung YJ, Winkler TW, Ntalla I, Guo X, Franceschini N, Cheng CY, Sim X, Vojinovic D, Marten J, Musani SK, Li C, Bentley AR, Brown MR, Schwander K, Richard MA, Noordam R, Aschard H, Bartz TM, Bielak LF, Dorajoo R, Fisher V, Hartwig FP, Horimoto ARVR, Lohman KK, Manning AK, Rankinen T, Smith AV, Tajuddin SM, Wojczynski MK, Alver M, Boissel M, Cai Q, Campbell A, Chai JF, Chen X, Divers J, Gao C, Goel A, Hagemeijer Y, Harris SE, He M, Hsu FC, Jackson AU, Kähönen M, Kasturiratne A, Komulainen P, Kühnel B, Laguzzi F, Luan J, Matoba N, Nolte IM, Padmanabhan S, Riaz M, Rueedi R, Robino A, Said MA, Scott RA, Sofer T, Stancáková A, Takeuchi F, Tayo BO, van der Most PJ, Varga TV, Vitart V, Wang Y, Ware EB, Warren HR, Weiss S, Wen W, Yanek LR, Zhang W, Zhao JH, Afaq S, Amin N, Amini M, Arking DE, Aung T, Boerwinkle E, Borecki I, Broeckel U, Brown M, Brumat M, Burke GL, Canouil M, Chakravarti A, Charumathi S, Ida Chen YD, Connell JM, Correa A, de Las Fuentes L, de Mutsert R, de Silva HJ, Deng X, Ding J, Duan Q, Eaton CB, Ehret G, Eppinga RN, Evangelou E, Faul JD, Felix SB, Forouhi NG, Forrester T, Franco OH, Friedlander Y, Gandin I, Gao H, Ghanbari M, Gigante B, Gu CC, Gu D, Hagenaars SP, Hallmans G, Harris TB, He J, Heikkinen S, Heng CK, Hirata M, Howard BV, Ikram MA, John U, Katsuya T, Khor CC, Kilpeläinen TO, Koh WP, Krieger JE, Kritchevsky SB, Kubo M, Kuusisto J, Lakka TA, Langefeld CD, Langenberg C, Launer LJ, Lehne B, Lewis CE, Li Y, Lin S, Liu J, Liu J, Loh M, Louie T, Mägi R, McKenzie CA, Meitinger T, Metspalu A, Milaneschi Y, Milani L, Mohlke KL, Momozawa Y, Nalls MA, Nelson CP, Sotoodehnia N, Norris JM, O'Connell JR, Palmer ND, Perls T, Pedersen NL, Peters A, Peyser PA, Poulter N, Raffel LJ, Raitakari OT, Roll K, Rose LM, Rosendaal FR, Rotter JI, Schmidt CO, Schreiner PJ, Schupf N, Scott WR, Sever PS, Shi Y, Sidney S, Sims M, Sitlani CM, Smith JA, Snieder H, Starr JM, Strauch K, Stringham HM, Tan NYQ, Tang H, Taylor KD, Teo YY, Tham YC, Turner ST, Uitterlinden AG, Vollenweider P, Waldenberger M, Wang L, Wang YX, Wei WB, Williams C, Yao J, Yu C, Yuan JM, Zhao W, Zonderman AB, Becker DM, Boehnke M, Bowden DW, Chambers JC, Deary IJ, Esko T, Farrall M, Franks PW, Freedman BI, Froguel P, Gasparini P, Gieger C, Jonas JB, Kamatani Y, Kato N, Kooner JS, Kutalik Z, Laakso M, Laurie CC, Leander K, Lehtimäki T, Study LC, Magnusson PKE, Oldehinkel AJ, Penninx BWJH, Polasek O, Porteous DJ, Rauramaa R, Samani NJ, Scott J, Shu XO, van der Harst P, Wagenknecht LE, Wareham NJ, Watkins H, Weir DR, Wickremasinghe AR, Wu T, Zheng W, Bouchard C, Christensen K, Evans MK, Gudnason V, Horta BL, Kardia SLR, Liu Y, Pereira AC, Psaty BM, Ridker PM, van Dam RM, Gauderman WJ, Zhu X, Mook-Kanamori DO, Fornage M, Rotimi CN, Cupples LA, Kelly TN, Fox ER, Hayward C, van Duijn CM, Tai ES, Wong TY, Kooperberg C, Palmas W, Rice K, Morrison AC, Elliott P, Caulfield MJ, Munroe PB, Rao DC, Province MA, Levy D. Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries. PLoS One. 2018; 13(6):e0198166.View Related Profiles. PMID: 29912962; PMCID: PMC6005576; DOI: 10.1371/journal.pone.0198166;
-
Marron MM, Singh J, Boudreau RM, Christensen K, Cosentino S, Feitosa MF, Minster RL, Perls T, Schupf N, Sebastiani P, Ukraintseva S, Wojczynski MK, Newman AB. A novel healthy blood pressure phenotype in the Long Life Family Study. J Hypertens. 2018 01; 36(1):43-53.View Related Profiles. PMID: 28837423; PMCID: PMC5893936; DOI: 10.1097/HJH.0000000000001514;
-
-
Sebastiani P, Gurinovich A, Bae H, Andersen S, Malovini A, Atzmon G, Villa F, Kraja AT, Ben-Avraham D, Barzilai N, Puca A, Perls TT. Four Genome-Wide Association Studies Identify New Extreme Longevity Variants. J Gerontol A Biol Sci Med Sci. 2017 Oct 12; 72(11):1453-1464.View Related Profiles. PMID: 28329165; PMCID: PMC5861867; DOI: 10.1093/gerona/glx027;
-
Macé A, Tuke MA, Deelen P, Kristiansson K, Mattsson H, Nõukas M, Sapkota Y, Schick U, Porcu E, Rüeger S, McDaid AF, Porteous D, Winkler TW, Salvi E, Shrine N, Liu X, Ang WQ, Zhang W, Feitosa MF, Venturini C, van der Most PJ, Rosengren A, Wood AR, Beaumont RN, Jones SE, Ruth KS, Yaghootkar H, Tyrrell J, Havulinna AS, Boers H, Mägi R, Kriebel J, Müller-Nurasyid M, Perola M, Nieminen M, Lokki ML, Kähönen M, Viikari JS, Geller F, Lahti J, Palotie A, Koponen P, Lundqvist A, Rissanen H, Bottinger EP, Afaq S, Wojczynski MK, Lenzini P, Nolte IM, Sparsø T, Schupf N, Christensen K, Perls TT, Newman AB, Werge T, Snieder H, Spector TD, Chambers JC, Koskinen S, Melbye M, Raitakari OT, Lehtimäki T, Tobin MD, Wain LV, Sinisalo J, Peters A, Meitinger T, Martin NG, Wray NR, Montgomery GW, Medland SE, Swertz MA, Vartiainen E, Borodulin K, Männistö S, Murray A, Bochud M, Jacquemont S, Rivadeneira F, Hansen TF, Oldehinkel AJ, Mangino M, Province MA, Deloukas P, Kooner JS, Freathy RM, Pennell C, Feenstra B, Strachan DP, Lettre G, Hirschhorn J, Cusi D, Heid IM, Hayward C, Männik K, Beckmann JS, Loos RJF, Nyholt DR, Metspalu A, Eriksson JG, Weedon MN, Salomaa V, Franke L, Reymond A, Frayling TM, Kutalik Z. CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits. Nat Commun. 2017 09 29; 8(1):744. PMID: 28963451; PMCID: PMC5622064; DOI: 10.1038/s41467-017-00556-x;
-
Perls TT. Male Centenarians: How and Why Are They Different from Their Female Counterparts? J Am Geriatr Soc. 2017 09; 65(9):1904-1906. PMID: 28586117; PMCID: PMC5603374; DOI: 10.1111/jgs.14978;
-
Fagan E, Sun F, Bae H, Elo I, Andersen SL, Lee J, Christensen K, Thyagarajan B, Sebastiani P, Perls T, Honig LS, Schupf N. Telomere length is longer in women with late maternal age. Menopause. 2017 May; 24(5):497-501.View Related Profiles. PMID: 27922939; PMCID: PMC5403597; DOI: 10.1097/GME.0000000000000795;
-
-
-
Sebastiani P, Thyagarajan B, Sun F, Honig LS, Schupf N, Cosentino S, Feitosa MF, Wojczynski M, Newman AB, Montano M, Perls TT. Age and Sex Distributions of Age-Related Biomarker Values in Healthy Older Adults from the Long Life Family Study. J Am Geriatr Soc. 2016 Nov; 64(11):e189-e194.View Related Profiles. PMID: 27783390; PMCID: PMC5118076; DOI: 10.1111/jgs.14522;
-
Pedersen JK, Elo IT, Schupf N, Perls TT, Stallard E, Yashin AI, Christensen K. The Survival of Spouses Marrying Into Longevity-Enriched Families. J Gerontol A Biol Sci Med Sci. 2017 Jan; 72(1):109-114. PMID: 27540092; PMCID: PMC5155661; DOI: 10.1093/gerona/glw159;
-
-
-
Ismail K, Nussbaum L, Sebastiani P, Andersen S, Perls T, Barzilai N, Milman S. Compression of Morbidity Is Observed Across Cohorts with Exceptional Longevity. J Am Geriatr Soc. 2016 Aug; 64(8):1583-91.View Related Profiles. PMID: 27377170; PMCID: PMC4988893; DOI: 10.1111/jgs.14222;
-
Sanders JL, Singh J, Minster RL, Walston JD, Matteini AM, Christensen K, Mayeux R, Borecki IB, Perls T, Newman AB. Association Between Mortality and Heritability of the Scale of Aging Vigor in Epidemiology. J Am Geriatr Soc. 2016 Aug; 64(8):1679-83. PMID: 27294813; PMCID: PMC4988884; DOI: 10.1111/jgs.14190;
-
-
Brodaty H, Woolf C, Andersen S, Barzilai N, Brayne C, Cheung KS, Corrada MM, Crawford JD, Daly C, Gondo Y, Hagberg B, Hirose N, Holstege H, Kawas C, Kaye J, Kochan NA, Lau BH, Lucca U, Marcon G, Martin P, Poon LW, Richmond R, Robine JM, Skoog I, Slavin MJ, Szewieczek J, Tettamanti M, Viña J, Perls T, Sachdev PS. ICC-dementia (International Centenarian Consortium - dementia): an international consortium to determine the prevalence and incidence of dementia in centenarians across diverse ethnoracial and sociocultural groups. BMC Neurol. 2016 Apr 21; 16:52.View Related Profiles. PMID: 27098177; PMCID: PMC4839126; DOI: 10.1186/s12883-016-0569-4;
-
Zeng Y, Nie C, Min J, Liu X, Li M, Chen H, Xu H, Wang M, Ni T, Li Y, Yan H, Zhang JP, Song C, Chi LQ, Wang HM, Dong J, Zheng GY, Lin L, Qian F, Qi Y, Liu X, Cao H, Wang Y, Zhang L, Li Z, Zhou Y, Wang Y, Lu J, Li J, Qi M, Bolund L, Yashin A, Land KC, Gregory S, Yang Z, Gottschalk W, Tao W, Wang J, Wang J, Xu X, Bae H, Nygaard M, Christiansen L, Christensen K, Franceschi C, Lutz MW, Gu J, Tan Q, Perls T, Sebastiani P, Deelen J, Slagboom E, Hauser E, Xu H, Tian XL, Yang H, Vaupel JW. Novel loci and pathways significantly associated with longevity. Sci Rep. 2016 Feb 25; 6:21243.View Related Profiles. PMID: 26912274; PMCID: PMC4766491; DOI: 10.1038/srep21243;
-
Perls T. Brocklehurst’s Textbook of Geriatric Medicine and Gerontology (Rockwood K, Fillit H, Young J, Eds.). Centenarians. Elsevir. New York City. 2016.
-
-
Nikolich-Žugich J, Goldman DP, Cohen PR, Cortese D, Fontana L, Kennedy BK, Mohler MJ, Olshansky SJ, Perls T, Perry D, Richardson A, Ritchie C, Wertheimer AM, Faragher RG, Fain MJ. Preparing for an Aging World: Engaging Biogerontologists, Geriatricians, and the Society. J Gerontol A Biol Sci Med Sci. 2016 Apr; 71(4):435-44. PMID: 26419976; PMCID: PMC5014189; DOI: 10.1093/gerona/glv164;
-
Honig LS, Kang MS, Cheng R, Eckfeldt JH, Thyagarajan B, Leiendecker-Foster C, Province MA, Sanders JL, Perls T, Christensen K, Lee JH, Mayeux R, Schupf N. Heritability of telomere length in a study of long-lived families. Neurobiol Aging. 2015 Oct; 36(10):2785-90. PMID: 26239175; PMCID: PMC4562863; DOI: 10.1016/j.neurobiolaging.2015.06.017;
-
Villa F, Carrizzo A, Spinelli CC, Ferrario A, Malovini A, Maciag A, Damato A, Auricchio A, Spinetti G, Sangalli E, Dang Z, Madonna M, Ambrosio M, Sitia L, Bigini P, Calì G, Schreiber S, Perls T, Fucile S, Mulas F, Nebel A, Bellazzi R, Madeddu P, Vecchione C, Puca AA. Genetic Analysis Reveals a Longevity-Associated Protein Modulating Endothelial Function and Angiogenesis. Circ Res. 2015 Jul 31; 117(4):333-45. PMID: 26034043; PMCID: PMC5496930; DOI: 10.1161/CIRCRESAHA.117.305875;
-
Sebastiani P, Nussbaum L, Andersen SL, Black MJ, Perls TT. Increasing Sibling Relative Risk of Survival to Older and Older Ages and the Importance of Precise Definitions of "Aging," "Life Span," and "Longevity". J Gerontol A Biol Sci Med Sci. 2016 Mar; 71(3):340-6.View Related Profiles. PMID: 25814633; PMCID: PMC4757962; DOI: 10.1093/gerona/glv020;
-
Perls T, Handelsman DJ. Disease mongering of age-associated declines in testosterone and growth hormone levels. J Am Geriatr Soc. 2015 Apr; 63(4):809-11. PMID: 25809947; DOI: 10.1111/jgs.13391;
-
Minster RL, Sanders JL, Singh J, Kammerer CM, Barmada MM, Matteini AM, Zhang Q, Wojczynski MK, Daw EW, Brody JA, Arnold AM, Lunetta KL, Murabito JM, Christensen K, Perls TT, Province MA, Newman AB. Genome-Wide Association Study and Linkage Analysis of the Healthy Aging Index. J Gerontol A Biol Sci Med Sci. 2015 Aug; 70(8):1003-8.View Related Profiles. PMID: 25758594; PMCID: PMC4506316; DOI: 10.1093/gerona/glv006;
-
Ash AS, Kroll-Desrosiers AR, Hoaglin DC, Christensen K, Fang H, Perls TT. Are Members of Long-Lived Families Healthier Than Their Equally Long-Lived Peers? Evidence From the Long Life Family Study. J Gerontol A Biol Sci Med Sci. 2015 Aug; 70(8):971-6. PMID: 25745037; PMCID: PMC4506317; DOI: 10.1093/gerona/glv015;
-
-
-
-
Barral S, Cosentino S, Christensen K, Newman AB, Perls TT, Province MA, Mayeux R. Common genetic variants on 6q24 associated with exceptional episodic memory performance in the elderly. JAMA Neurol. 2014 Dec; 71(12):1514-9. PMID: 25317765; PMCID: PMC4355405; DOI: 10.1001/jamaneurol.2014.1663;
-
-
Broer L, Buchman AS, Deelen J, Evans DS, Faul JD, Lunetta KL, Sebastiani P, Smith JA, Smith AV, Tanaka T, Yu L, Arnold AM, Aspelund T, Benjamin EJ, De Jager PL, Eirkisdottir G, Evans DA, Garcia ME, Hofman A, Kaplan RC, Kardia SL, Kiel DP, Oostra BA, Orwoll ES, Parimi N, Psaty BM, Rivadeneira F, Rotter JI, Seshadri S, Singleton A, Tiemeier H, Uitterlinden AG, Zhao W, Bandinelli S, Bennett DA, Ferrucci L, Gudnason V, Harris TB, Karasik D, Launer LJ, Perls TT, Slagboom PE, Tranah GJ, Weir DR, Newman AB, van Duijn CM, Murabito JM. GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacy. J Gerontol A Biol Sci Med Sci. 2015 Jan; 70(1):110-8.View Related Profiles. PMID: 25199915; PMCID: PMC4296168; DOI: 10.1093/gerona/glu166;
-
-
Lee JH, Cheng R, Honig LS, Feitosa M, Kammerer CM, Kang MS, Schupf N, Lin SJ, Sanders JL, Bae H, Druley T, Perls T, Christensen K, Province M, Mayeux R. Genome wide association and linkage analyses identified three loci-4q25, 17q23.2, and 10q11.21-associated with variation in leukocyte telomere length: the Long Life Family Study. Front Genet. 2013; 4:310. PMID: 24478790; PMCID: PMC3894567; DOI: 10.3389/fgene.2013.00310;
-
An P, Miljkovic I, Thyagarajan B, Kraja AT, Daw EW, Pankow JS, Selvin E, Kao WH, Maruthur NM, Nalls MA, Liu Y, Harris TB, Lee JH, Borecki IB, Christensen K, Eckfeldt JH, Mayeux R, Perls TT, Newman AB, Province MA. Genome-wide association study identifies common loci influencing circulating glycated hemoglobin (HbA1c) levels in non-diabetic subjects: the Long Life Family Study (LLFS). Metabolism. 2014 Apr; 63(4):461-8. PMID: 24405752; PMCID: PMC3965585; DOI: 10.1016/j.metabol.2013.11.018;
-
Sebastiani P, Sun FX, Andersen SL, Lee JH, Wojczynski MK, Sanders JL, Yashin A, Newman AB, Perls TT. Families Enriched for Exceptional Longevity also have Increased Health-Span: Findings from the Long Life Family Study. Front Public Health. 2013; 1:38.View Related Profiles. PMID: 24350207; PMCID: PMC3859985; DOI: 10.3389/fpubh.2013.00038;
-
Sebastiani P, Bae H, Sun FX, Andersen SL, Daw EW, Malovini A, Kojima T, Hirose N, Schupf N, Puca A, Perls TT. Meta-analysis of genetic variants associated with human exceptional longevity. Aging (Albany NY). 2013 Sep; 5(9):653-61.View Related Profiles. PMID: 24244950; PMCID: PMC3808698; DOI: 10.18632/aging.100594;
-
Sanders JL, Minster RL, Barmada MM, Matteini AM, Boudreau RM, Christensen K, Mayeux R, Borecki IB, Zhang Q, Perls T, Newman AB. Heritability of and mortality prediction with a longevity phenotype: the healthy aging index. J Gerontol A Biol Sci Med Sci. 2014 Apr; 69(4):479-85. PMID: 23913930; PMCID: PMC3968826; DOI: 10.1093/gerona/glt117;
-
Barral S, Cosentino S, Costa R, Andersen SL, Christensen K, Eckfeldt JH, Newman AB, Perls TT, Province MA, Hadley EC, Rossi WK, Mayeux R. Exceptional memory performance in the Long Life Family Study. Neurobiol Aging. 2013 Nov; 34(11):2445-8.View Related Profiles. PMID: 23759147; PMCID: PMC4095822; DOI: 10.1016/j.neurobiolaging.2013.05.002;
-
Perls T. The reappearance of procaine hydrochloride (Gerovital H3) for antiaging. J Am Geriatr Soc. 2013 Jun; 61(6):1024-5. PMID: 23772727; DOI: 10.1111/jgs.12278;
-
Elo IT, Mykyta L, Sebastiani P, Christensen K, Glynn NW, Perls T. Age validation in the long life family study through a linkage to early-life census records. J Gerontol B Psychol Sci Soc Sci. 2013 Jul; 68(4):580-5.View Related Profiles. PMID: 23704206; PMCID: PMC3674734; DOI: 10.1093/geronb/gbt033;
-
-
-
-
-
Conneely KN, Capell BC, Erdos MR, Sebastiani P, Solovieff N, Swift AJ, Baldwin CT, Budagov T, Barzilai N, Atzmon G, Puca AA, Perls TT, Geesaman BJ, Boehnke M, Collins FS. Human longevity and common variations in the LMNA gene: a meta-analysis. Aging Cell. 2012 Jun; 11(3):475-81.View Related Profiles. PMID: 22340368; PMCID: PMC3350595; DOI: 10.1111/j.1474-9726.2012.00808.x;
-
Michael Anson R, Willcox B, Austad S, Perls T. Within- and between-species study of extreme longevity--comments, commonalities, and goals. J Gerontol A Biol Sci Med Sci. 2012 Apr; 67(4):347-50. PMID: 22419221; PMCID: PMC3309878; DOI: 10.1093/gerona/gls010;
-
Sebastiani P, Solovieff N, Dewan AT, Walsh KM, Puca A, Hartley SW, Melista E, Andersen S, Dworkis DA, Wilk JB, Myers RH, Steinberg MH, Montano M, Baldwin CT, Hoh J, Perls TT. Genetic signatures of exceptional longevity in humans. PLoS One. 2012; 7(1):e29848.View Related Profiles. PMID: 22279548; PMCID: PMC3261167; DOI: 10.1371/journal.pone.0029848;
-
Andersen SL, Sebastiani P, Dworkis DA, Feldman L, Perls TT. Health span approximates life span among many supercentenarians: compression of morbidity at the approximate limit of life span. J Gerontol A Biol Sci Med Sci. 2012 Apr; 67(4):395-405.View Related Profiles. PMID: 22219514; PMCID: PMC3309876; DOI: 10.1093/gerona/glr223;
-
Sebastiani P, Riva A, Montano M, Pham P, Torkamani A, Scherba E, Benson G, Milton JN, Baldwin CT, Andersen S, Schork NJ, Steinberg MH, Perls TT. Whole genome sequences of a male and female supercentenarian, ages greater than 114?years. Front Genet. 2011; 2:90.View Related Profiles. PMID: 22303384; PMCID: PMC3262222; DOI: 10.3389/fgene.2011.00090;
-
Sebastiani P, Solovieff N, Puca A, Hartley SW, Melista E, Andersen S, Dworkis DA, Wilk JB, Myers RH, Steinberg MH, Montano M, Baldwin CT, Perls TT. Retraction. Science. 2011 Jul 22; 333(6041):404.View Related Profiles. PMID: 21778381; DOI: 10.1126/science.333.6041.404-a;
-
Kulminski AM, Arbeev KG, Christensen K, Mayeux R, Newman AB, Province MA, Hadley EC, Rossi W, Perls TT, Elo IT, Yashin AI. Do gender, disability, and morbidity affect aging rate in the LLFS? Application of indices of cumulative deficits. Mech Ageing Dev. 2011 Apr; 132(4):195-201. PMID: 21463647; PMCID: PMC3139988; DOI: 10.1016/j.mad.2011.03.006;
-
Young RD, Desjardins B, McLaughlin K, Poulain M, Perls TT. Typologies of extreme longevity myths. Curr Gerontol Geriatr Res. 2010; 2010:423087. PMID: 21461047; PMCID: PMC3062986; DOI: 10.1155/2010/423087;
-
Newman AB, Glynn NW, Taylor CA, Sebastiani P, Perls TT, Mayeux R, Christensen K, Zmuda JM, Barral S, Lee JH, Simonsick EM, Walston JD, Yashin AI, Hadley E. Health and function of participants in the Long Life Family Study: A comparison with other cohorts. Aging (Albany NY). 2011 Jan; 3(1):63-76.View Related Profiles. PMID: 21258136; PMCID: PMC3047140; DOI: 10.18632/aging.100242;
-
-
Sebastiani P, Solovieff N, Puca A, Hartley SW, Melista E, Andersen S, Dworkis DA, Wilk JB, Myers RH, Steinberg MH, Montano M, Baldwin CT, Perls TT. Genetic signatures of exceptional longevity in humans. Science. 2010 Jul 1; 2010.View Related Profiles. PMID: 20595579; DOI: 10.1126/science.1190532;
-
-
-
Sebastiani P, Montano M, Puca A, Solovieff N, Kojima T, Wang MC, Melista E, Meltzer M, Fischer SE, Andersen S, Hartley SH, Sedgewick A, Arai Y, Bergman A, Barzilai N, Terry DF, Riva A, Anselmi CV, Malovini A, Kitamoto A, Sawabe M, Arai T, Gondo Y, Steinberg MH, Hirose N, Atzmon G, Ruvkun G, Baldwin CT, Perls TT. RNA editing genes associated with extreme old age in humans and with lifespan in C. elegans. PLoS One. 2009; 4(12):e8210.View Related Profiles. PMID: 20011587; PMCID: PMC2788130; DOI: 10.1371/journal.pone.0008210;
-
Sebastiani P, Hadley EC, Province M, Christensen K, Rossi W, Perls TT, Ash AS. A family longevity selection score: ranking sibships by their longevity, size, and availability for study. Am J Epidemiol. 2009 Dec 15; 170(12):1555-62.View Related Profiles. PMID: 19910380; PMCID: PMC2800272; DOI: 10.1093/aje/kwp309;
-
Perls TT. Growth hormone and anabolic steroids: athletes are the tip of the iceberg. Drug Test Anal. 2009 Sep; 1(9-10):419-25. PMID: 20355224; DOI: 10.1002/dta.87;
-
-
-
-
-
-
Olshansky SJ, Perls TT. New developments in the illegal provision of growth hormone for "anti-aging" and bodybuilding. JAMA. 2008 Jun 18; 299(23):2792-4. PMID: 18560007; DOI: 10.1001/jama.299.23.2792;
-
-
Sebastiani P, Zhao Z, Abad-Grau MM, Riva A, Hartley SW, Sedgewick AE, Doria A, Montano M, Melista E, Terry D, Perls TT, Steinberg MH, Baldwin CT. A hierarchical and modular approach to the discovery of robust associations in genome-wide association studies from pooled DNA samples. BMC Genet. 2008; 9:6.View Related Profiles. PMID: 18194558; PMCID: PMC2248205; DOI: 10.1186/1471-2156-9-6;
-
Perls T. Aging, Biotechnology, and the Future (Read CY, Green RC, Smyer MA, Eds.). Centenarians and genetics. Johns Hopkins University Press. 2008.
-
Sebastiani P, Perls T. Bayesian Belief Networks: A Practical Guide to Applications (Pourret O, Naim P, Marcot BG, Eds.). Complex Genetic Models. Wiley. New York. 2008.
-
-
Perls TT. DHEA and testosterone in the elderly. N Engl J Med. 2007 Feb 8; 356(6):636; author reply 637. PMID: 17288051
-
Poon LW, Perls TT. Annual Review of Gerontology And Geriatrics: Biopsychosocial Approaches to Longevity (Poon L, Perls T, Eds.). The trials and tribulations of studying the oldest old. Springer. 2007.
-
Perls TT. Annual Review of Gerontology and Geriatrics: Biopsychosocial Approaches to Longevity (Poon L, Perls T, Eds.). The familiality of exceptional longevity. Springer. 2007.
-
Perls T, Sebastiani P. Molecular Biology of Aging (Guarente LP, Partridge L, Wallace DC, Eds.). Genetics of exceptional longevity. Cold Spring Harbor Laboratory Press. 2007.
-
Annual Review of Gerontology And Geriatrics: Biopsychosocial Approaches to Longevity (Poon L, Perls T, Eds.). Springer. 2007.
-
Perls TT. Hope drives antiaging hype. Cleve Clin J Med. 2006 Dec; 73(12):1039-40, 1044. PMID: 17190307
-
-
Perls TT. The different paths to 100. Am J Clin Nutr. 2006 Feb; 83(2):484S-487S. PMID: 16470017
-
Perls T. Encyclopedia of Aging ( Schulz R, Noelker LS, Rockwood K, Sprott R, Eds.). Centenarians. Springer. 2006.
-
Perls T. Handbook of Models for Human Aging (Conn PM, Ed.). Human Models of Longevity. Elsevier. New York. 2006.
-
Perls T. The different paths to age one hundred. Ann N Y Acad Sci. 2005 Dec; 1055:13-25. PMID: 16387714
-
Warner H, Anderson J, Austad S, Bergamini E, Bredesen D, Butler R, Carnes BA, Clark BF, Cristofalo V, Faulkner J, Guarente L, Harrison DE, Kirkwood T, Lithgow G, Martin G, Masoro E, Melov S, Miller RA, Olshansky SJ, Partridge L, Pereira-Smith O, Perls T, Richardson A, Smith J, von Zglinicki T, Wang E, Wei JY, Williams TF. Science fact and the SENS agenda. What can we reasonably expect from ageing research? EMBO Rep. 2005 Nov; 6(11):1006-8. PMID: 16264422; PMCID: PMC1371037; DOI: 10.1038/sj.embor.7400555;
-
Perls TT, Reisman NR, Olshansky SJ. Provision or distribution of growth hormone for "antiaging": clinical and legal issues. JAMA. 2005 Oct 26; 294(16):2086-90. PMID: 16249424
-
Li-Sucholeiki XC, Hu G, Perls T, Tomita-Mitchell A, Thilly WG. Scanning the beta-globin gene for mutations in large populations by denaturing capillary and gel electrophoresis. Electrophoresis. 2005 Jun; 26(13):2531-8. PMID: 15948210
-
Andersen SL, Terry DF, Wilcox MA, Babineau T, Malek K, Perls TT. Cancer in the oldest old. Mech Ageing Dev. 2005 Feb; 126(2):263-7.View Related Profiles. PMID: 15621206
-
Terry DF, Wilcox MA, McCormick MA, Pennington JY, Schoenhofen EA, Andersen SL, Perls TT. Lower all-cause, cardiovascular, and cancer mortality in centenarians' offspring. J Am Geriatr Soc. 2004 Dec; 52(12):2074-6.View Related Profiles. PMID: 15571545
-
Bernstein AM, Willcox BJ, Tamaki H, Kunishima N, Suzuki M, Willcox DC, Yoo JS, Perls TT. First autopsy study of an Okinawan centenarian: absence of many age-related diseases. J Gerontol A Biol Sci Med Sci. 2004 Nov; 59(11):1195-9. PMID: 15602075
-
Perls T. Dementia-free centenarians. Exp Gerontol. 2004 Nov-Dec; 39(11-12):1587-93. PMID: 15582273
-
Perls T. Centenarians who avoid dementia. Trends Neurosci. 2004 Oct; 27(10):633-6. PMID: 15374676
-
Perls TT. Anti-aging quackery: human growth hormone and tricks of the trade--more dangerous than ever. J Gerontol A Biol Sci Med Sci. 2004 Jul; 59(7):682-91. PMID: 15304532
-
Terry DF, McCormick M, Andersen S, Pennington J, Schoenhofen E, Palaima E, Bausero M, Ogawa K, Perls TT, Asea A. Cardiovascular disease delay in centenarian offspring: role of heat shock proteins. Ann N Y Acad Sci. 2004 Jun; 1019:502-5.View Related Profiles. PMID: 15247074; PMCID: PMC1764488
-
Mor V, Perls TT. Robine and Michel's "Looking forward to a general theory on population aging": measuring functional decline in population aging in a changing world and an evolving biology. J Gerontol A Biol Sci Med Sci. 2004 Jun; 59(6):M609-11; author reply M616-20. PMID: 15215279
-
Olshansky SJ, Hayflick L, Perls TT. The hype and the reality--part I. J Gerontol A Biol Sci Med Sci. 2004 Jun; 59(6):B513-4. PMID: 15215255
-
Terry DF, Wilcox MA, McCormick MA, Perls TT. Cardiovascular disease delay in centenarian offspring. J Gerontol A Biol Sci Med Sci. 2004 Apr; 59(4):385-9.View Related Profiles. PMID: 15071083
-
Perls T, Terry D. Principles and Practice of Geriatric Medicine (Pathy MSJ, Morley JE, Sinclair A, Eds.). Centenarians. Wiley. Chichester, England. 2004.
-
Geesaman BJ, Benson E, Brewster SJ, Kunkel LM, Blanché H, Thomas G, Perls TT, Daly MJ, Puca AA. Haplotype-based identification of a microsomal transfer protein marker associated with the human lifespan. Proc Natl Acad Sci U S A. 2003 Nov 25; 100(24):14115-20. PMID: 14615589; PMCID: PMC283555
-
Perls T, Terry D. Understanding the determinants of exceptional longevity. Ann Intern Med. 2003 Sep 2; 139(5 Pt 2):445-9.View Related Profiles. PMID: 12965974
-
Butler RN, Austad SN, Barzilai N, Braun A, Helfand S, Larsen PL, McCormick AM, Perls TT, Shuldiner AR, Sprott RL, Warner HR. Longevity genes: from primitive organisms to humans. J Gerontol A Biol Sci Med Sci. 2003 Jul; 58(7):581-4. PMID: 12865472
-
-
Terry DF, Wilcox M, McCormick MA, Lawler E, Perls TT. Cardiovascular advantages among the offspring of centenarians. J Gerontol A Biol Sci Med Sci. 2003 May; 58(5):M425-31.View Related Profiles. PMID: 12730251
-
Evert J, Lawler E, Bogan H, Perls T. Morbidity profiles of centenarians: survivors, delayers, and escapers. J Gerontol A Biol Sci Med Sci. 2003 Mar; 58(3):232-7. PMID: 12634289
-
Arking R, Butler B, Chiko B, Fossel M, Gavrilov LA, Morley JE, Olshansky SJ, Perls T, Walker RF. Anti-aging teleconference: what is anti-aging medicine? J Anti Aging Med. 2003; 6(2):91-106. PMID: 14614799
-
Butler RN, Fossel M, Harman SM, Heward CB, Olshansky SJ, Perls TT, Rothman DJ, Rothman SM, Warner HR, West MD, Wright WE. Is there an antiaging medicine? J Gerontol A Biol Sci Med Sci. 2002 Sep; 57(9):B333-8. PMID: 12196485
-
Perls T, Kunkel LM, Puca AA. The genetics of exceptional human longevity. J Mol Neurosci. 2002 Aug-Oct; 19(1-2):233-8. PMID: 12212788
-
Perls T, Puca A. The genetics of aging-- implications for pharmacogenomics. Pharmacogenomics. 2002 Jul; 3(4):469-84. PMID: 12164771
-
Fillit HM, Butler RN, O'Connell AW, Albert MS, Birren JE, Cotman CW, Greenough WT, Gold PE, Kramer AF, Kuller LH, Perls TT, Sahagan BG, Tully T. Achieving and maintaining cognitive vitality with aging. Mayo Clin Proc. 2002 Jul; 77(7):681-96. PMID: 12108606
-
Perls TT, Wilmoth J, Levenson R, Drinkwater M, Cohen M, Bogan H, Joyce E, Brewster S, Kunkel L, Puca A. Life-long sustained mortality advantage of siblings of centenarians. Proc Natl Acad Sci U S A. 2002 Jun 11; 99(12):8442-7. PMID: 12060785; PMCID: PMC123086
-
Perls T, Kunkel L, Puca A. The genetics of aging. Curr Opin Genet Dev. 2002 Jun; 12(3):362-9. PMID: 12076681
-
Silver MH, Newell K, Brady C, Hedley-White ET, Perls TT. Distinguishing between neurodegenerative disease and disease-free aging: correlating neuropsychological evaluations and neuropathological studies in centenarians. Psychosom Med. 2002 May-Jun; 64(3):493-501. PMID: 12021423
-
Perls T. Genetic and environmental influences on exceptional longevity and the AGE nomogram. Ann N Y Acad Sci. 2002 Apr; 959:1-13. PMID: 11976180
-
Perls T, Kunkel LM, Puca AA. The genetics of exceptional human longevity. J Am Geriatr Soc. 2002 Feb; 50(2):359-68. PMID: 12028221
-
Perls T, Levenson R, Regan M, Puca A. What does it take to live to 100? Mech Ageing Dev. 2002 Jan; 123(2-3):231-42. PMID: 11718815
-
Puca AA, Daly MJ, Brewster SJ, Matise TC, Barrett J, Shea-Drinkwater M, Kang S, Joyce E, Nicoli J, Benson E, Kunkel LM, Perls T. A genome-wide scan for linkage to human exceptional longevity identifies a locus on chromosome 4. Proc Natl Acad Sci U S A. 2001 Aug 28; 98(18):10505-8. PMID: 11526246; PMCID: PMC56990
-
Perls TT, Fretts RC. The evolution of menopause and human life span. Ann Hum Biol. 2001 May-Jun; 28(3):237-45. PMID: 11393331
-
Silver MH, Jilinskaia E, Perls TT. Cognitive functional status of age-confirmed centenarians in a population-based study. J Gerontol B Psychol Sci Soc Sci. 2001 May; 56(3):P134-40. PMID: 11316831
-
Vijg J, Perls T, Franceschi C, van Orsouw NJ. BRCA1 gene sequence variation in centenarians. Ann N Y Acad Sci. 2001 Apr; 928:85-96. PMID: 11795532
-
Perls T. Genetic and phenotypic markers among centenarians. J Gerontol A Biol Sci Med Sci. 2001 Feb; 56(2):M67-70. PMID: 11213277
-
Newell KL, Silver MH, Perls TT, Hedley-Whyte ET. Envejecimiento cerebral y enfermedad (Martinez Lage JM, Hachinski V, Eds.). What centenarians teach us about neuropathology. Editorial Triacastela. Madrid. 2001; 31-46.
-
Perls T, Shea-Drinkwater M, Bowen-Flynn J, Ridge SB, Kang S, Joyce E, Daly M, Brewster SJ, Kunkel L, Puca AA. Exceptional familial clustering for extreme longevity in humans. J Am Geriatr Soc. 2000 Nov; 48(11):1483-5. PMID: 11083328
-
Perls T, Daly M, Brewster S, Puca A, Kunkel L. Sex and Longevity: Sexuality, Gender, Reproduction, Parenthood (Robine JM, Kirkwood TBL, Allard M, Eds.). Genes and Centenarians. Springer Verlag. Heidelberg. 2000; 43-57.
-
Perls T, Terry D, Silver M, Shea M, Bowen J, Joyce E, Ridge SB, Fretts R, Daly M, Brewster S, Puca A, Kunkel L. Molecular Genetics of Aging (Hekimi S, Ed.). Centenarians and The Genetics of Longevity. Springer. Germany. 2000; 29:1-20.
-
Perls T, Terry DF, Silver M, Shea M, Bowen J, Joyce E, Ridge SB, Fretts R, Daly M, Brewster S, Puca A, Kunkel L. Centenarians and the genetics of longevity. Results Probl Cell Differ. 2000; 29:1-20.View Related Profiles. PMID: 10838692
-
Hitt R, Young-Xu Y, Silver M, Perls T. Centenarians: the older you get, the healthier you have been. Lancet. 1999 Aug 21; 354(9179):652. PMID: 10466675
-
Khrapko K, Bodyak N, Thilly WG, van Orsouw NJ, Zhang X, Coller HA, Perls TT, Upton M, Vijg J, Wei JY. Cell-by-cell scanning of whole mitochondrial genomes in aged human heart reveals a significant fraction of myocytes with clonally expanded deletions. Nucleic Acids Res. 1999 Jun 1; 27(11):2434-41. PMID: 10325435; PMCID: PMC148812
-
Perls T, Silver M, Lauerman J. Living to 100: Lessons In Living to Your Maximum Potential At Any Age. Basic Books. New York. 1999.
-
Perls TT, Bochen K, Freeman M, Alpert L, Silver MH. Validity of reported age and centenarian prevalence in New England. Age Ageing. 1999 Mar; 28(2):193-7. PMID: 10350418
-
Perls TT, Bubrick E, Wager CG, Vijg J, Kruglyak L. Siblings of centenarians live longer. Lancet. 1998 May 23; 351(9115):1560. PMID: 10326548
-
Silver M, Newell K, Hyman B, Growdon J, Hedley-Whyte ET, Perls T. Unraveling the mystery of cognitive changes in old age: correlation of neuropsychological evaluation with neuropathological findings in the extreme old. Int Psychogeriatr. 1998 Mar; 10(1):25-41. PMID: 9629522
-
Perls TT, Bochen K, Freeman M, Alpert L, Silver MH. Age Validation of the Extreme Old (Jeune B, Vaupel J, Eds.). The New England Centenarian Study: validity of reported age and prevalence of centenarians in an eight town sample. Odense University Press. Odense. 1998.
-
Alpert L, Vaupel J, Perls T. Age Validation of the Extreme Old. ( Jeune B, Vaupel J, Eds.). Extreme longevity in a family. A report of multiple centenarians within a
single generation. Odense University Press. Odense. 1998.
-
Perls TT. Centenarians prove the compression of morbidity hypothesis, but what about the rest of us who are genetically less fortunate? Med Hypotheses. 1997 Nov; 49(5):405-7. PMID: 9421805
-
Perls TT, Alpert L, Fretts RC. Middle-aged mothers live longer. Nature. 1997 Sep 11; 389(6647):133. PMID: 9296486
-
Perls TT. Acute care costs of the oldest old. Hosp Pract (1995). 1997 Jul 15; 32(7):123-4, 129-32, 137. PMID: 9227662
-
Perls TT, Wood ER. Acute care costs of the oldest old: they cost less, their care intensity is less, and they go to nonteaching hospitals. Arch Intern Med. 1996 Apr 8; 156(7):754-60. PMID: 8615708
-
Gomez-Isla T, West HL, Rebeck GW, Harr SD, Growdon JH, Locascio JJ, Perls TT, Lipsitz LA, Hyman BT. Clinical and pathological correlates of apolipoprotein E epsilon 4 in Alzheimer's disease. Ann Neurol. 1996 Jan; 39(1):62-70. PMID: 8572669
-
Perls TT, Mace N, Morris J. The HRCA Manual (Lipsitz LA, Morris J, Murphy K, Eds.). Cognitive Loss and Dementia in Quality Care for the Nursing Home Resident. Eliot Press. Natick, MA. 1996.
-
Perls TT. Apolipoprotein E and its association with Alzheimer's disease. J Insur Med. 1996; 28(2):114-8. PMID: 10172880
-
Perls TT, Herget M. Higher respiratory infection rates on an Alzheimer's special care unit and successful intervention. J Am Geriatr Soc. 1995 Dec; 43(12):1341-4. PMID: 7490383
-
Perls TT. The oldest old. Sci Am. 1995 Jan; 272(1):70-5. PMID: 7824916
-
Rebeck GW, Perls TT, West HL, Sodhi P, Lipsitz LA, Hyman BT. Reduced apolipoprotein epsilon 4 allele frequency in the oldest old Alzheimer's patients and cognitively normal individuals. Neurology. 1994 Aug; 44(8):1513-6. PMID: 8058160
-
Perls TT, Morris JN, Ooi WL, Lipsitz LA. The relationship between age, gender and cognitive performance in the very old: the effect of selective survival. J Am Geriatr Soc. 1993 Nov; 41(11):1193-201. PMID: 8227893
-
Castle SC, Norman DC, Perls TT, Chang MP, Yoshikawa TT, Makinodan T. Analysis of cutaneous delayed-type hypersensitivity reaction and T cell proliferative response in elderly nursing home patients: an approach to identifying immunodeficient patients. Gerontology. 1990; 36(4):217-29. PMID: 2272525