Tatiana B. Prokaeva, MD, PhD
Assistant Professor
Boston University Chobanian & Avedisian School of Medicine
Pathology & Laboratory Medicine

MD, Medical Semashko Institute
PhD, Russian Academy of Medical Sciences



Expertise in genetics of primary and familial types of amyloidosis.

Member
Boston University
Amyloidosis Center




SCAN-MP (Screening for Cardiac Amyloidosis with Nuclear Imaging in Minority Populations)
05/01/2019 - 02/29/2024 (Subcontract PI)
Boston Medical Center Corporation NIH NHLBI
5R01HL139671-04

Preclinical evaluation of amyloid binding on tissues and opsonization using CAEL-101
10/02/2022 - 10/01/2023 (PI)
Alexion Pharmaceuticals, Inc.


ALA Study - Janssen Pharmaceuticals
06/09/2020 - 06/09/2023 (PI)
Janssen Research & Development, LLC




Title


Yr Title Project-Sub Proj Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Edwards CV, Ferri GM, Villegas-Galaviz J, Ghosh S, Bawa PS, Wang F, Klimtchuk E, Ajayi TB, Morgan GJ, Prokaeva T, Staron A, Ruberg FL, Sanchorawala V, Giadone RM, Murphy GJ. Abnormal global longitudinal strain and reduced serum inflammatory markers in cardiac AL amyloidosis patients without significant amyloid fibril deposition. bioRxiv. 2024 Mar 16.View Related Profiles. PMID: 38558967; PMCID: PMC10980073; DOI: 10.1101/2024.03.14.584987;
     
  2. Lau KHV, Prokaeva T, Zheng L, Doros G, Kaku MC, Spencer B, Berk J, Sanchorawala V. Neurofilament light chain kinetics as a biomarker for polyneuropathy in V122I hereditary transthyretin amyloidosis. Amyloid. 2023 Dec 11; 1-3.View Related Profiles. PMID: 38073425
     
  3. Mendelson L, Prokaeva T, Lau KHV, Sanchorawala V, McCausland K, Spencer B, Dasari S, McPhail ED, Kaku MC. Hereditary gelsolin amyloidosis: a rare cause of cranial, peripheral and autonomic neuropathies linked to D187N and Y447H substitutions. Amyloid. 2023 Dec; 30(4):357-363.View Related Profiles. PMID: 37140928
     
  4. Nau A, Shen Y, Sanchorawala V, Prokaeva T, Morgan GJ. Complete variable domain sequences of monoclonal antibody light chains identified from untargeted RNA sequencing data. Front Immunol. 2023; 14:1167235.View Related Profiles. PMID: 37143670; PMCID: PMC10151772; DOI: 10.3389/fimmu.2023.1167235;
     
  5. Prokaeva T, Klimtchuk ES, Feschenko P, Spencer B, Cui H, Burks EJ, Aslebagh R, Muneeruddin K, Shaffer SA, Varghese E, Berk JL, Connors LH. An additive destabilising effect of compound T60I and V122I substitutions in ATTRv amyloidosis. Amyloid. 2023 Jun; 30(2):141-152.View Related Profiles. PMID: 36286264
     
  6. Prokaeva T, Joshi T, Klimtchuk ES, Gibson VM, Spencer B, Siddiqi O, Nedelkov D, Hu Y, Berk JL, Cuddy SAM, Dasari S, Chiu A, Choate LA, McPhail ED, Cui H, Chen H, Burks EJ, Sanchorawala V, Connors LH. A novel substitution of proline (P32L) destabilises ß2-microglobulin inducing hereditary systemic amyloidosis. Amyloid. 2022 Dec; 29(4):255-262.View Related Profiles. PMID: 35575118; DOI: 10.1080/13506129.2022.2072199;
     
  7. Klimtchuk ES, Prokaeva T, Frame NM, Abdullahi HA, Spencer B, Dasari S, Cui H, Berk JL, Kurtin PJ, Connors LH, Gursky O. Unusual duplication mutation in a surface loop of human transthyretin leads to an aggressive drug-resistant amyloid disease. Proc Natl Acad Sci U S A. 2018 07 10; 115(28):E6428-E6436.View Related Profiles. PMID: 29941560; PMCID: PMC6048550; DOI: 10.1073/pnas.1802977115;
     
  8. Hanson JLS, Arvanitis M, Koch CM, Berk JL, Ruberg FL, Prokaeva T, Connors LH. Use of Serum Transthyretin as a Prognostic Indicator and Predictor of Outcome in Cardiac Amyloid Disease Associated With Wild-Type Transthyretin. Circ Heart Fail. 2018 02; 11(2):e004000.View Related Profiles. PMID: 29449366; PMCID: PMC5819619; DOI: 10.1161/CIRCHEARTFAILURE.117.004000;
     
  9. Prokaeva T, Akar H, Spencer B, Havasi A, Cui H, O'Hara CJ, Gursky O, Leszyk J, Steffen M, Browning S, Rosenberg A, Connors LH. Hereditary Renal Amyloidosis Associated With a Novel Apolipoprotein A-II Variant. Kidney Int Rep. 2017 Nov; 2(6):1223-1232.View Related Profiles. PMID: 29270531; PMCID: PMC5733886; DOI: 10.1016/j.ekir.2017.07.009;
     
  10. Klimtchuk ES, Prokaeva TB, Spencer BH, Gursky O, Connors LH. In vitro co-expression of human amyloidogenic immunoglobulin light and heavy chain proteins: a relevant cell-based model of AL amyloidosis. Amyloid. 2017 Jun; 24(2):115-122.View Related Profiles. PMID: 28632419; PMCID: PMC5580339; DOI: 10.1080/13506129.2017.1336996;
     
Showing 10 of 30 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 30 publications over 18 distinct years, with a maximum of 3 publications in 2007 and 2023

YearPublications
19901
19911
20001
20022
20032
20061
20073
20081
20092
20111
20122
20141
20162
20172
20182
20222
20233
20241

In addition to these self-described keywords below, a list of MeSH based concepts is available here.

familial amyloidosis
primary amyloidosis
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