Philip Trackman | Profiles RNS

Philip C. Trackman, PhD

Emeritus Professor

Boston University Henry M. Goldman School of Dental Medicine

Translational Dental Medicine

PhD, Boston University
BA, College of Wooster

Websites

	Dental Medicine Periodontology & Oral Biology Faculty
	Linkedin
	ResearchGate
	Dr. Philip Trackman awarded Department of Defense grant for prostate cancer research

ORCID : 0000-0001-5064-614X

Dr. Philip Trackman is an Emeritus Professor in the Department of Translational Dental Medicine at the Boston University Henry M. Goldman School of Dental Medicine. Dr. Trackman is also an important member of the Oral Cancer Research Initiative (OCRI) and is currently investigating the molecular mechanisms of the connective tissue enzyme, lysyl oxidase, and its potential therapeutic effects in oral cancer. A third area of interest is mechanisms of diabetic bone disease, in which he has recently provided evidence for dysregulation of osteoblast lysyl oxidase by gastric hormones in diabetes to be a determining mechanism in this pathology.

Dr. Trackman became interested in cancer research in 1990, after cloning lysyl oxidase for the very first time. This enzyme family has tumor inhibitory properties and also enhances tissue fibrosis and metastasis. In the context of the OCRI, Dr. Trackman is working to investigate the two therapeutic opportunities which these findings suggest. His first aim is to explore how to inhibit the harmful activity of the active enzymes, while taking advantage of the tumor growth inhibitory activity of the lysyl oxidase propeptide. The lysyl oxidase propeptide was shown by Dr. Trackman’s lab in 2004 to be responsible for the tumor growth inhibitory properties of lysyl oxidase. His lab has confirmed this in animal models of both breast and prostate cancer, and recently also in oral cancer. Dr. Trackman collaborated on this project with Research Assistant Professor Dr. Manish Bais, who is also an OCRI investigator.

Dr. Trackman’s ongoing research will establish the extent to which new and powerful lysyl oxidase family enzyme activity inhibitors can block human oral cancer tumor growth and/or metastasis in mice. This work is funded by the OCRI’s Etiology and Pathogenesis of Oral Cancer Affinity Research Collaborative (ARC) as a part of Boston University’s Evans Center for Interdisciplinary Biomedical Research. In addition, modifications to the structure of the lysyl oxidase propeptide are underway with the goal of enhancing its tumor growth inhibitory properties, and also to identify its most important binding partners in its ability to inhibit tumor growth.

Director of Graduate Programs, Molecular & Cell Biology
Boston University Henry M. Goldman School of Dental Medicine
Molecular & Cell Biology

Research Assistant Professor
Boston University Chobanian & Avedisian School of Medicine
Biochemistry & Cell Biology

Member
Boston University
BU-BMC Cancer Center

Member
Boston University
Evans Center for Interdisciplinary Biomedical Research

Member
Boston University
Genome Science Institute

Graduate Faculty (Primary Mentor of Grad Students)
Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences

BU Research
NIH RePORTER Research

Mechanism of Bone Marrow Neoplasm-Induced Osteosclerosis
05/01/2018 - 04/30/2020 (Multi-PI)
PI: Philip C. Trackman, PhD
NIH/National Institute of Arthritis & Musculoskeletal & Skin Diseases
5R21AR072748-02

Lysyl Oxidase Dysregulation in Diabetic Bone Disease
08/16/2016 - 08/15/2018 (Key Person / Mentor)
PI: Eileen Daley
NIH/National Institute of Dental & Craniofacial Research
5F31DE026685-02

Biological Activit of Lysyl Oxidase Like-2 Inhibitors
04/01/2015 - 12/31/2017 (PI)
Pharmaxis

Cellular or Extracellular Targeting of Lysyl Oxidase Propeptide for Oral Cancer
07/01/2014 - 06/30/2017 (PI)
NIH/National Institute of Dental & Craniofacial Research
5R21DE023973-02

Inhibited Intramembraneous Bone Healing in Diabetes
03/01/2009 - 01/31/2016 (PI)
NIH/National Institute of Dental & Craniofacial Research
5R01DE014066-10

Growth Factors and Gingival Fibrosis
04/01/1994 - 06/30/2012 (PI)
NIH/National Institute of Dental & Craniofacial Research
5 R01 DE11004 15

Lysyl Oxidase Inhibition of Ras-Mediated Transformation
09/01/1999 - 04/30/2010 (Co-PI)
NIH/National Cancer Institute
5 R01 CA82742 10

Mechanisms of Mineralized Matrix Accumulation
02/01/1999 - 01/31/2004 (PI)
NIH/National Institute of Dental & Craniofacial Research
5 R01 DE12209 04

Screen Fibrogen anti-CTGF Antibodies for Blocking Activity
05/15/2001 - 05/14/2002 (PI)
FibroGen Inc

Phenotypic Reversion Requires Lysyl Oxidase mRNA
09/15/1998 - 09/14/2000 (PI)
NIH/National Institute of Dental & Craniofacial Research
5 R03 DE12425 02

Title

Yr	Title	Project-Sub Proj	Pubs
2022	Osteoblast Dopamine Receptor Mediates Diabetic Bone Disease	5R21AR077260-02
2021	Osteoblast Dopamine Receptor Mediates Diabetic Bone Disease	1R21AR077260-01A1
2019	Mechanism of Bone Marrow Neoplasm-Induced Osteosclerosis	5R21AR072748-02	1
2018	Mechanism of Bone Marrow Neoplasm-Induced Osteosclerosis	1R21AR072748-01	1
2015	Cellular or Extracellular Targeting of Lysyl Oxidase Propeptide for Oral Cancer	5R21DE023973-02	8
2014	Cellular or Extracellular Targeting of Lysyl Oxidase Propeptide for Oral Cancer	1R21DE023973-01A1	8
2013	Inhibited Intramembranous Bone Healing in Diabetes	5R01DE014066-10	31
2012	Inhibited Intramembranous Bone Healing in Diabetes	5R01DE014066-09	31
2011	Inhibited Intramembranous Bone Healing in Diabetes	5R01DE014066-08	31
2011	Growth Factors and Gingival Fibrosis	5R01DE011004-15	33

Showing 10 of 41 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis Copy PMIDs To Clipboard

Peymanfar Y, Mahjour F, Shrestha N, de la Cueva A, Chen Y, Huang S, Kirsch KH, Han X, Trackman PC. The Lysyl Oxidase G473A Polymorphism Exacerbates Oral Cancer Development in Humans and Mice. Int J Mol Sci. 2023 May 28; 24(11).View Related Profiles.

Mahjour, Faranak
Trackman, Philip

PMID: 37298359; PMCID: PMC10254048; DOI: 10.3390/ijms24119407;

Trackman PC. Multifunctional Lysyl Oxidases. Int J Mol Sci. 2023 Mar 23; 24(7). PMID: 37047014; PMCID: PMC10094348; DOI: 10.3390/ijms24076044;

Trackman PC, Peymanfar Y, Roy S. Functions and Mechanisms of Pro-Lysyl Oxidase Processing in Cancers and Eye Pathologies with a Focus on Diabetic Retinopathy. Int J Mol Sci. 2022 May 03; 23(9).View Related Profiles.

Trackman, Philip
Roy, Sayon

PMID: 35563478; PMCID: PMC9105217; DOI: 10.3390/ijms23095088;

Daley EJ, Trackman PC. ß-Catenin mediates glucose-dependent insulinotropic polypeptide increases in lysyl oxidase expression in osteoblasts. Bone Rep. 2021 Jun; 14:101063.View Related Profiles.

Daley, Eileen
Trackman, Philip

PMID: 33981809; PMCID: PMC8081922; DOI: 10.1016/j.bonr.2021.101063;

Kim D, Lee D, Trackman PC, Roy S. Effects of High Glucose-Induced Lysyl Oxidase Propeptide on Retinal Endothelial Cell Survival: Implications for Diabetic Retinopathy. Am J Pathol. 2019 10; 189(10):1945-1952.View Related Profiles.

Trackman, Philip
Roy, Sayon

PMID: 31537300; PMCID: PMC6880772; DOI: 10.1016/j.ajpath.2019.06.004;

Daley EJ, Pajevic PD, Roy S, Trackman PC. Impaired Gastric Hormone Regulation of Osteoblasts and Lysyl Oxidase Drives Bone Disease in Diabetes Mellitus. JBMR Plus. 2019 Oct; 3(10):e10212.View Related Profiles.

Daley, Eileen
Trackman, Philip
Roy, Sayon

PMID: 31687648; PMCID: PMC6820454; DOI: 10.1002/jbm4.10212;

Lee VS, Halabi CM, Broekelmann TJ, Trackman PC, Stitziel NO, Mecham RP. Intracellular retention of mutant lysyl oxidase leads to aortic dilation in response to increased hemodynamic stress. JCI Insight. 2019 06 18; 5. PMID: 31211696; PMCID: PMC6693828; DOI: 10.1172/jci.insight.127748;

Mahjour F, Dambal V, Shrestha N, Singh V, Noonan V, Kantarci A, Trackman PC. Mechanism for oral tumor cell lysyl oxidase like-2 in cancer development: synergy with PDGF-AB. Oncogenesis. 2019 May 13; 8(5):34.View Related Profiles.

Mahjour, Faranak
Trackman, Philip
Noonan, Vikki

PMID: 31086173; PMCID: PMC6513832; DOI: 10.1038/s41389-019-0144-0;

de la Cueva A, Emmerling M, Lim SL, Yang S, Trackman PC, Sonenshein GE, Kirsch KH. A polymorphism in the lysyl oxidase propeptide domain accelerates carcinogen-induced cancer. Carcinogenesis. 2018 07 03; 39(7):921-930.View Related Profiles.

Kirsch, Kathrin
Trackman, Philip
Yang, Shi

PMID: 29579155; PMCID: PMC6692853; DOI: 10.1093/carcin/bgy045;

Saxena D, Mahjour F, Findlay AD, Mously EA, Kantarci A, Trackman PC. Multiple Functions of Lysyl Oxidase Like-2 in Oral Fibroproliferative Processes. J Dent Res. 2018 10; 97(11):1277-1284.View Related Profiles.

Saxena, Debashree
Mahjour, Faranak
Trackman, Philip

PMID: 29787337; PMCID: PMC6151912; DOI: 10.1177/0022034518775971;

Showing 10 of 117 results. Show More

Herzog CR, Berzins DW, DenBesten P, Gregory RL, Hargreaves KM, Messer RLW, Mina M, Mooney MP, Paine ML, Phillips C, Presland RB, Quivey RG, Scannapieco FA, Sheridan JF, Svoboda KKH, Trackman PC, Walker MP, Walker SG, Wang CY, Hu JCC. Oral Sciences PhD Program Enrollment, Graduates, and Placement: 1994 to 2016. J Dent Res. 2018 05; 97(5):483-491. PMID: 29328868; PMCID: PMC6728576; DOI: 10.1177/0022034517749506;

Trackman PC. Functional importance of lysyl oxidase family propeptide regions. J Cell Commun Signal. 2018 Mar; 12(1):45-53. PMID: 29086201; PMCID: PMC5842187; DOI: 10.1007/s12079-017-0424-4;

Trackman PC, Bais MV. Measurement of lysyl oxidase activity from small tissue samples and cell cultures. Methods Cell Biol. 2018; 143:147-156.View Related Profiles.

Bais, Manish
Trackman, Philip

PMID: 29310775

Bais MV, Kukuruzinska M, Trackman PC. Corrigendum to "Orthotopic non-metastatic and metastatic oral cancer mouse models" [Oral Oncol. 51(5) (2015) 476-482]. Oral Oncol. 2017 09; 72:201.View Related Profiles.

Bais, Manish
Kukuruzinska, Maria
Trackman, Philip

PMID: 28743466

Kim D, Mecham RP, Trackman PC, Roy S. Downregulation of Lysyl Oxidase Protects Retinal Endothelial Cells From High Glucose-Induced Apoptosis. Invest Ophthalmol Vis Sci. 2017 May 01; 58(5):2725-2731.View Related Profiles.

Trackman, Philip
Roy, Sayon

PMID: 28538980; PMCID: PMC5444550; DOI: 10.1167/iovs.16-21340;

Sánchez-Morgan N, Kirsch KH, Trackman PC, Sonenshein GE. UXT Is a LOX-PP Interacting Protein That Modulates Estrogen Receptor Alpha Activity in Breast Cancer Cells. J Cell Biochem. 2017 Aug; 118(8):2347-2356.View Related Profiles.

Kirsch, Kathrin
Trackman, Philip

PMID: 28106301; DOI: 10.1002/jcb.25893;

Trackman PC, Saxena D, Bais MV. TGF-ß1- and CCN2-Stimulated Sirius Red Assay for Collagen Accumulation in Cultured Cells. Methods Mol Biol. 2017; 1489:481-485.View Related Profiles.

Saxena, Debashree
Bais, Manish
Trackman, Philip

PMID: 27734398

Trackman PC. Lysyl Oxidase Isoforms and Potential Therapeutic Opportunities for Fibrosis and Cancer. Expert Opin Ther Targets. 2016 Aug; 20(8):935-45. PMID: 26848785; PMCID: PMC4988797; DOI: 10.1517/14728222.2016.1151003;

Matsuura S, Mi R, Koupenova M, Eliades A, Patterson S, Toselli P, Thon J, Italiano JE, Trackman PC, Papadantonakis N, Ravid K. Lysyl oxidase is associated with increased thrombosis and platelet reactivity. Blood. 2016 Mar 17; 127(11):1493-501.View Related Profiles.

Ravid, Katya
Koupenova-Zamor, Milka
Toselli, Paul
Trackman, Philip
Mi, Rongjuan
Matsuura, Shinobu

PMID: 26755713; PMCID: PMC4797025; DOI: 10.1182/blood-2015-02-629667;

Trackman PC. Enzymatic and non-enzymatic functions of the lysyl oxidase family in bone. Matrix Biol. 2016 May-Jul; 52-54:7-18. PMID: 26772152; PMCID: PMC4875786; DOI: 10.1016/j.matbio.2016.01.001;

Alsulaiman M, Bais MV, Trackman PC. Lysyl oxidase propeptide stimulates osteoblast and osteoclast differentiation and enhances PC3 and DU145 prostate cancer cell effects on bone in vivo. J Cell Commun Signal. 2016 Mar; 10(1):17-31.View Related Profiles.

Bais, Manish
Trackman, Philip

PMID: 26627907; PMCID: PMC4850135; DOI: 10.1007/s12079-015-0311-9;

Alsofi L, Daley E, Hornstra I, Morgan EF, Mason ZD, Acevedo JF, Word RA, Gerstenfeld LC, Trackman PC. Sex-Linked Skeletal Phenotype of Lysyl Oxidase Like-1 Mutant Mice. Calcif Tissue Int. 2016 Feb; 98(2):172-85.View Related Profiles.

Daley, Eileen
Morgan, Elise
Gerstenfeld, Louis
Trackman, Philip

PMID: 26538021; DOI: 10.1007/s00223-015-0076-4;

Ozdener GB, Bais MV, Trackman PC. Determination of cell uptake pathways for tumor inhibitor lysyl oxidase propeptide. Mol Oncol. 2016 Jan; 10(1):1-23.View Related Profiles.

Bais, Manish
Trackman, Philip

PMID: 26297052; PMCID: PMC4549800; DOI: 10.1016/j.molonc.2015.07.005;

Assaggaf MA, Kantarci A, Sume SS, Trackman PC. Prevention of phenytoin-induced gingival overgrowth by lovastatin in mice. Am J Pathol. 2015 Jun; 185(6):1588-99.View Related Profiles.

Trackman, Philip
Sume, Siddika

PMID: 25843680; PMCID: PMC4450317; DOI: 10.1016/j.ajpath.2015.02.004;

Trackman PC. An interesting perspective on a well-studied pathway: does type III TGF-? receptor have therapeutic potential? J Cell Commun Signal. 2015 Mar; 9(1):103. PMID: 25700691; PMCID: PMC4414836; DOI: 10.1007/s12079-015-0284-8;

Trackman PC, Kantarci A. Molecular and clinical aspects of drug-induced gingival overgrowth. J Dent Res. 2015 Apr; 94(4):540-6. PMID: 25680368; PMCID: PMC4485217; DOI: 10.1177/0022034515571265;

Bais MV, Kukuruzinska M, Trackman PC. Orthotopic non-metastatic and metastatic oral cancer mouse models. Oral Oncol. 2015 May; 51(5):476-82.View Related Profiles.

Bais, Manish
Kukuruzinska, Maria
Trackman, Philip

PMID: 25682387; PMCID: PMC4427342; DOI: 10.1016/j.oraloncology.2015.01.012;

Khosravi R, Trackman PC. Diabetes-induced fibrotic matrix inhibits intramembranous bone healing. J Cell Commun Signal. 2015 Mar; 9(1):19-26. PMID: 25186349; PMCID: PMC4414841; DOI: 10.1007/s12079-014-0242-x;

Khosravi R, Sodek KL, Xu WP, Bais MV, Saxena D, Faibish M, Trackman PC. A novel function for lysyl oxidase in pluripotent mesenchymal cell proliferation and relevance to inflammation-associated osteopenia. PLoS One. 2014; 9(6):e100669.View Related Profiles.

Saxena, Debashree
Bais, Manish
Trackman, Philip

PMID: 24971753; PMCID: PMC4074096; DOI: 10.1371/journal.pone.0100669;

Bais MV, Ozdener GB, Sonenshein GE, Trackman PC. Effects of tumor-suppressor lysyl oxidase propeptide on prostate cancer xenograft growth and its direct interactions with DNA repair pathways. Oncogene. 2015 Apr 9; 34(15):1928-37.View Related Profiles.

Bais, Manish
Trackman, Philip

PMID: 24882580; PMCID: PMC4254378; DOI: 10.1038/onc.2014.147;

Perbal B, Trackman P, Castellot J, Brigstock D, Takigawa M, Lau L, Leask A. Report on the 7(th) international workshop on the CCN family of genes : October 16-19, 2013-Nice, France. J Cell Commun Signal. 2014 Mar; 8(1):71-6. PMID: 24553917; PMCID: PMC3972399; DOI: 10.1007/s12079-014-0227-9;

Sato S, Zhao Y, Imai M, Simister PC, Feller SM, Trackman PC, Kirsch KH, Sonenshein GE. Inhibition of CIN85-mediated invasion by a novel SH3 domain binding motif in the lysyl oxidase propeptide. PLoS One. 2013; 8(10):e77288.View Related Profiles.

Sonenshein, Gail
Kirsch, Kathrin
Trackman, Philip

PMID: 24167568; PMCID: PMC3805583; DOI: 10.1371/journal.pone.0077288;

Khosravi R, Sodek KL, Faibish M, Trackman PC. Collagen advanced glycation inhibits its Discoidin Domain Receptor 2 (DDR2)-mediated induction of lysyl oxidase in osteoblasts. Bone. 2014 Jan; 58:33-41. PMID: 24120383; PMCID: PMC3851576; DOI: 10.1016/j.bone.2013.10.001;

Bahammam M, Black SA, Sume SS, Assaggaf MA, Faibish M, Trackman PC. Requirement for active glycogen synthase kinase-3ß in TGF-ß1 upregulation of connective tissue growth factor (CCN2/CTGF) levels in human gingival fibroblasts. Am J Physiol Cell Physiol. 2013 Sep 15; 305(6):C581-90.View Related Profiles.

Trackman, Philip
Sume, Siddika

PMID: 23824844; PMCID: PMC3761177; DOI: 10.1152/ajpcell.00032.2013;

Beerlage C, Greb J, Kretschmer D, Assaggaf M, Trackman PC, Hansmann ML, Bonin M, Eble JA, Peschel A, Brüne B, Kempf VA. Hypoxia-inducible factor 1-regulated lysyl oxidase is involved in Staphylococcus aureus abscess formation. Infect Immun. 2013 Jul; 81(7):2562-73. PMID: 23649089; PMCID: PMC3697610; DOI: 10.1128/IAI.00302-13;

Eliades A, Papadantonakis N, Matsuura S, Mi R, Bais MV, Trackman P, Ravid K. Megakaryocyte polyploidy is inhibited by lysyl oxidase propeptide. Cell Cycle. 2013 Apr 15; 12(8):1242-50.View Related Profiles.

Ravid, Katya
Bais, Manish
Trackman, Philip
Mi, Rongjuan
Matsuura, Shinobu

PMID: 23518500; PMCID: PMC3674089; DOI: 10.4161/cc.24312;

Yu Z, Sato S, Trackman PC, Kirsch KH, Sonenshein GE. Blimp1 activation by AP-1 in human lung cancer cells promotes a migratory phenotype and is inhibited by the lysyl oxidase propeptide. PLoS One. 2012; 7(3):e33287.View Related Profiles.

Sonenshein, Gail
Kirsch, Kathrin
Trackman, Philip

PMID: 22438909; PMCID: PMC3305320; DOI: 10.1371/journal.pone.0033287;

Bais MV, Nugent MA, Stephens DN, Sume SS, Kirsch KH, Sonenshein GE, Trackman PC. Recombinant lysyl oxidase propeptide protein inhibits growth and promotes apoptosis of pre-existing murine breast cancer xenografts. PLoS One. 2012; 7(2):e31188.View Related Profiles.

Sonenshein, Gail
Kirsch, Kathrin
Bais, Manish
Nugent, Matthew
Trackman, Philip
Sume, Siddika

PMID: 22363577; PMCID: PMC3280126; DOI: 10.1371/journal.pone.0031188;

Sánchez-Morgan N, Kirsch KH, Trackman PC, Sonenshein GE. The lysyl oxidase propeptide interacts with the receptor-type protein tyrosine phosphatase kappa and inhibits ß-catenin transcriptional activity in lung cancer cells. Mol Cell Biol. 2011 Aug; 31(16):3286-97.View Related Profiles.

Sonenshein, Gail
Kirsch, Kathrin
Trackman, Philip

PMID: 21690299; PMCID: PMC3147807; DOI: 10.1128/MCB.01426-10;

Eliades A, Papadantonakis N, Bhupatiraju A, Burridge KA, Johnston-Cox HA, Migliaccio AR, Crispino JD, Lucero HA, Trackman PC, Ravid K. Control of megakaryocyte expansion and bone marrow fibrosis by lysyl oxidase. J Biol Chem. 2011 Aug 5; 286(31):27630-8.View Related Profiles.

Bhupatiraju, Ajoy
Johnston-Cox, Hillary
Ravid, Katya
Trackman, Philip

PMID: 21665949; PMCID: PMC3149354; DOI: 10.1074/jbc.M111.243113;

Sato S, Trackman PC, Mäki JM, Myllyharju J, Kirsch KH, Sonenshein GE. The Ras signaling inhibitor LOX-PP interacts with Hsp70 and c-Raf to reduce Erk activation and transformed phenotype of breast cancer cells. Mol Cell Biol. 2011 Jul; 31(13):2683-95.View Related Profiles.

Sonenshein, Gail
Kirsch, Kathrin
Trackman, Philip

PMID: 21536655; PMCID: PMC3133379; DOI: 10.1128/MCB.01148-10;

Kantarci A, Nseir Z, Kim YS, Sume SS, Trackman PC. Loss of basement membrane integrity in human gingival overgrowth. J Dent Res. 2011 Jul; 90(7):887-93.View Related Profiles.

Trackman, Philip
Sume, Siddika

PMID: 21483030; PMCID: PMC3148006; DOI: 10.1177/0022034511404703;

Chen H, Koupenova M, Yang D, Sume SS, Trackman PC, Ravid K. Regulation of MMP-9 expression by the A2b adenosine receptor and its dependency on TNF-a signaling. Exp Hematol. 2011 May; 39(5):525-30.View Related Profiles.

Ravid, Katya
Koupenova-Zamor, Milka
Trackman, Philip
Sume, Siddika

PMID: 21320567; PMCID: PMC5983365; DOI: 10.1016/j.exphem.2011.02.004;

Grimsby JL, Lucero HA, Trackman PC, Ravid K, Kagan HM. Role of lysyl oxidase propeptide in secretion and enzyme activity. J Cell Biochem. 2010 Dec 1; 111(5):1231-43.View Related Profiles.

Kagan, Herbert
Ravid, Katya
Trackman, Philip

PMID: 20717923; PMCID: PMC3858906; DOI: 10.1002/jcb.22845;

Min C, Zhao Y, Romagnoli M, Trackman PC, Sonenshein GE, Kirsch KH. Lysyl oxidase propeptide sensitizes pancreatic and breast cancer cells to doxorubicin-induced apoptosis. J Cell Biochem. 2010 Dec 1; 111(5):1160-8.View Related Profiles.

Sonenshein, Gail
Kirsch, Kathrin
Trackman, Philip
Zhao, Yingshe

PMID: 20717927; PMCID: PMC3907072; DOI: 10.1002/jcb.22828;

Iftikhar M, Hurtado P, Bais MV, Wigner N, Stephens DN, Gerstenfeld LC, Trackman PC. Lysyl oxidase-like-2 (LOXL2) is a major isoform in chondrocytes and is critically required for differentiation. J Biol Chem. 2011 Jan 14; 286(2):909-18.View Related Profiles.

Gerstenfeld, Louis
Bais, Manish
Trackman, Philip

PMID: 21071451; PMCID: PMC3020776; DOI: 10.1074/jbc.M110.155622;

Chronopoulos A, Tang A, Beglova E, Trackman PC, Roy S. High glucose increases lysyl oxidase expression and activity in retinal endothelial cells: mechanism for compromised extracellular matrix barrier function. Diabetes. 2010 Dec; 59(12):3159-66.View Related Profiles.

Trackman, Philip
Roy, Sayon

PMID: 20823103; PMCID: PMC2992778; DOI: 10.2337/db10-0365;

Sume SS, Kantarci A, Lee A, Hasturk H, Trackman PC. Epithelial to mesenchymal transition in gingival overgrowth. Am J Pathol. 2010 Jul; 177(1):208-18.View Related Profiles.

Trackman, Philip
Sume, Siddika

PMID: 20489142; PMCID: PMC2893664; DOI: 10.2353/ajpath.2010.090952;

Vora SR, Guo Y, Stephens DN, Salih E, Vu ED, Kirsch KH, Sonenshein GE, Trackman PC. Characterization of recombinant lysyl oxidase propeptide. Biochemistry. 2010 Apr 6; 49(13):2962-72.View Related Profiles.

Salih, Erdjan
Sonenshein, Gail
Kirsch, Kathrin
Trackman, Philip

PMID: 20192271; PMCID: PMC2847845; DOI: 10.1021/bi902218p;

Vora SR, Palamakumbura AH, Mitsi M, Guo Y, Pischon N, Nugent MA, Trackman PC. Lysyl oxidase propeptide inhibits FGF-2-induced signaling and proliferation of osteoblasts. J Biol Chem. 2010 Mar 5; 285(10):7384-93.View Related Profiles.

Nugent, Matthew
Trackman, Philip

PMID: 20048148; PMCID: PMC2844187; DOI: 10.1074/jbc.M109.033597;

Min C, Yu Z, Kirsch KH, Zhao Y, Vora SR, Trackman PC, Spicer DB, Rosenberg L, Palmer JR, Sonenshein GE. A loss-of-function polymorphism in the propeptide domain of the LOX gene and breast cancer. Cancer Res. 2009 Aug 15; 69(16):6685-93.View Related Profiles.

Sonenshein, Gail
Palmer, Julie
Kirsch, Kathrin
Rosenberg, Lynn
Trackman, Philip
Zhao, Yingshe

PMID: 19654310; PMCID: PMC2729564; DOI: 10.1158/0008-5472.CAN-08-4818;

Palamakumbura AH, Vora SR, Nugent MA, Kirsch KH, Sonenshein GE, Trackman PC. Lysyl oxidase propeptide inhibits prostate cancer cell growth by mechanisms that target FGF-2-cell binding and signaling. Oncogene. 2009 Sep 24; 28(38):3390-400.View Related Profiles.

Sonenshein, Gail
Kirsch, Kathrin
Nugent, Matthew
Trackman, Philip

PMID: 19597471; PMCID: PMC2753565; DOI: 10.1038/onc.2009.203;

Pischon N, Mäki JM, Weisshaupt P, Heng N, Palamakumbura AH, N'Guessan P, Ding A, Radlanski R, Renz H, Bronckers TA, Myllyharju J, Kielbassa AM, Kleber BM, Bernimoulin JP, Trackman PC. Lysyl oxidase (lox) gene deficiency affects osteoblastic phenotype. Calcif Tissue Int. 2009 Aug; 85(2):119-26. PMID: 19458888; PMCID: PMC2827261; DOI: 10.1007/s00223-009-9252-8;

Zhao Y, Min C, Vora SR, Trackman PC, Sonenshein GE, Kirsch KH. The lysyl oxidase pro-peptide attenuates fibronectin-mediated activation of focal adhesion kinase and p130Cas in breast cancer cells. J Biol Chem. 2009 Jan 16; 284(3):1385-93.View Related Profiles.

Sonenshein, Gail
Kirsch, Kathrin
Trackman, Philip
Zhao, Yingshe

PMID: 19029090; PMCID: PMC2615524; DOI: 10.1074/jbc.M802612200;

Gonçalves LD, Oliveira G, Hurtado PA, Feitosa A, Takiya CM, Granjeiro JM, Trackman PC, Otazú I, Feres-Filho EJ. Expression of metalloproteinases and their tissue inhibitors in inflamed gingival biopsies. J Periodontal Res. 2008 Oct; 43(5):570-7. PMID: 18624953; DOI: 10.1111/j.1600-0765.2008.01101.x;

Weishaupt P, Bernimoulin JP, Trackman P, Hägewald S. Stimulation of osteoblasts with Emdogain increases the expression of specific mineralization markers. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008 Aug; 106(2):304-8. PMID: 18547835; DOI: 10.1016/j.tripleo.2008.02.033;

Black SA, Trackman PC. Transforming growth factor-beta1 (TGFbeta1) stimulates connective tissue growth factor (CCN2/CTGF) expression in human gingival fibroblasts through a RhoA-independent, Rac1/Cdc42-dependent mechanism: statins with forskolin block TGFbeta1-induced CCN2/CTGF expression. J Biol Chem. 2008 Apr 18; 283(16):10835-47. PMID: 18287089; PMCID: PMC2435243; DOI: 10.1074/jbc.M710363200;

Hurtado PA, Vora S, Sume SS, Yang D, St Hilaire C, Guo Y, Palamakumbura AH, Schreiber BM, Ravid K, Trackman PC. Lysyl oxidase propeptide inhibits smooth muscle cell signaling and proliferation. Biochem Biophys Res Commun. 2008 Feb 1; 366(1):156-61.View Related Profiles.

Schreiber, Barbara
Ravid, Katya
Trackman, Philip
Sume, Siddika

PMID: 18060869; PMCID: PMC2211633; DOI: 10.1016/j.bbrc.2007.11.116;

Kakar S, Einhorn TA, Vora S, Miara LJ, Hon G, Wigner NA, Toben D, Jacobsen KA, Al-Sebaei MO, Song M, Trackman PC, Morgan EF, Gerstenfeld LC, Barnes GL. Enhanced chondrogenesis and Wnt signaling in PTH-treated fractures. J Bone Miner Res. 2007 Dec; 22(12):1903-12.View Related Profiles.

Morgan, Elise
Gerstenfeld, Louis
Trackman, Philip
Einhorn, Thomas

PMID: 17680724

Kantarci A, Augustin P, Firatli E, Sheff MC, Hasturk H, Graves DT, Trackman PC. Apoptosis in gingival overgrowth tissues. J Dent Res. 2007 Sep; 86(9):888-92. PMID: 17720861; PMCID: PMC2909491; DOI: 10.1177/154405910708600916;

Wu M, Min C, Wang X, Yu Z, Kirsch KH, Trackman PC, Sonenshein GE. Repression of BCL2 by the tumor suppressor activity of the lysyl oxidase propeptide inhibits transformed phenotype of lung and pancreatic cancer cells. Cancer Res. 2007 Jul 1; 67(13):6278-85.View Related Profiles.

Sonenshein, Gail
Kirsch, Kathrin
Trackman, Philip

PMID: 17616686

Black SA, Palamakumbura AH, Stan M, Trackman PC. Tissue-specific mechanisms for CCN2/CTGF persistence in fibrotic gingiva: interactions between cAMP and MAPK signaling pathways, and prostaglandin E2-EP3 receptor mediated activation of the c-JUN N-terminal kinase. J Biol Chem. 2007 May 25; 282(21):15416-29. PMID: 17428796; PMCID: PMC2443949; DOI: 10.1074/jbc.M610432200;

Guo Y, Pischon N, Palamakumbura AH, Trackman PC. Intracellular distribution of the lysyl oxidase propeptide in osteoblastic cells. Am J Physiol Cell Physiol. 2007 Jun; 292(6):C2095-102. PMID: 17287363

Min C, Kirsch KH, Zhao Y, Jeay S, Palamakumbura AH, Trackman PC, Sonenshein GE. The tumor suppressor activity of the lysyl oxidase propeptide reverses the invasive phenotype of Her-2/neu-driven breast cancer. Cancer Res. 2007 Feb 1; 67(3):1105-12.View Related Profiles.

Sonenshein, Gail
Kirsch, Kathrin
Trackman, Philip
Zhao, Yingshe

PMID: 17283144

Ding Y, Kantarci A, Hasturk H, Trackman PC, Malabanan A, Van Dyke TE. Activation of RAGE induces elevated O2- generation by mononuclear phagocytes in diabetes. J Leukoc Biol. 2007 Feb; 81(2):520-7.View Related Profiles.

Malabanan, Alan
Trackman, Philip
Van Dyke, Thomas

PMID: 17095613; PMCID: PMC2533418; DOI: 10.1189/jlb.0406262;

Alikhani M, Alikhani Z, Boyd C, MacLellan CM, Raptis M, Liu R, Pischon N, Trackman PC, Gerstenfeld L, Graves DT. Advanced glycation end products stimulate osteoblast apoptosis via the MAP kinase and cytosolic apoptotic pathways. Bone. 2007 Feb; 40(2):345-53.View Related Profiles.

Gerstenfeld, Louis
Trackman, Philip

PMID: 17064973; PMCID: PMC1913208; DOI: 10.1016/j.bone.2006.09.011;

Alikhani M, Maclellan CM, Raptis M, Vora S, Trackman PC, Graves DT. Advanced glycation end products induce apoptosis in fibroblasts through activation of ROS, MAP kinases, and the FOXO1 transcription factor. Am J Physiol Cell Physiol. 2007 Feb; 292(2):C850-6. PMID: 17005604

Santana RB, Trackman PC. Controlled release of fibroblast growth factor 2 stimulates bone healing in an animal model of diabetes mellitus. Int J Oral Maxillofac Implants. 2006 Sep-Oct; 21(5):711-8. PMID: 17066631

Kantarci A, Black SA, Xydas CE, Murawel P, Uchida Y, Yucekal-Tuncer B, Atilla G, Emingil G, Uzel MI, Lee A, Firatli E, Sheff M, Hasturk H, Van Dyke TE, Trackman PC. Epithelial and connective tissue cell CTGF/CCN2 expression in gingival fibrosis. J Pathol. 2006 Sep; 210(1):59-66.View Related Profiles.

Trackman, Philip
Van Dyke, Thomas

PMID: 16841303; PMCID: PMC1557679; DOI: 10.1002/path.2000;

Heng EC, Huang Y, Black SA, Trackman PC. CCN2, connective tissue growth factor, stimulates collagen deposition by gingival fibroblasts via module 3 and alpha6- and beta1 integrins. J Cell Biochem. 2006 May 15; 98(2):409-20. PMID: 16440322; PMCID: PMC1435777; DOI: 10.1002/jcb.20810;

Graves DT, Liu R, Alikhani M, Al-Mashat H, Trackman PC. Diabetes-enhanced inflammation and apoptosis--impact on periodontal pathology. J Dent Res. 2006 Jan; 85(1):15-21. PMID: 16373675

Trackman PC. Diverse biological functions of extracellular collagen processing enzymes. J Cell Biochem. 2005 Dec 1; 96(5):927-37. PMID: 16167328; PMCID: PMC1352157; DOI: 10.1002/jcb.20605;

Karima M, Kantarci A, Ohira T, Hasturk H, Jones VL, Nam BH, Malabanan A, Trackman PC, Badwey JA, Van Dyke TE. Enhanced superoxide release and elevated protein kinase C activity in neutrophils from diabetic patients: association with periodontitis. J Leukoc Biol. 2005 Oct; 78(4):862-70.View Related Profiles.

Malabanan, Alan
Trackman, Philip
Ohira, Taisuke
Van Dyke, Thomas

PMID: 16081595; PMCID: PMC1249507; DOI: 10.1189/jlb.1004583;

Pischon N, Babakhanlou-Chase H, Darbois L, Ho WB, Brenner MC, Kessler E, Palamakumbura AH, Trackman PC. A procollagen C-proteinase inhibitor diminishes collagen and lysyl oxidase processing but not collagen cross-linking in osteoblastic cultures. J Cell Physiol. 2005 Apr; 203(1):111-7. PMID: 15368541

Alikhani Z, Alikhani M, Boyd CM, Nagao K, Trackman PC, Graves DT. Advanced glycation end products enhance expression of pro-apoptotic genes and stimulate fibroblast apoptosis through cytoplasmic and mitochondrial pathways. J Biol Chem. 2005 Apr 1; 280(13):12087-95. PMID: 15590648

Palamakumbura AH, Jeay S, Guo Y, Pischon N, Sommer P, Sonenshein GE, Trackman PC. The propeptide domain of lysyl oxidase induces phenotypic reversion of ras-transformed cells. J Biol Chem. 2004 Sep 24; 279(39):40593-600.View Related Profiles.

Sonenshein, Gail
Trackman, Philip

PMID: 15277520

Hong HH, Pischon N, Santana RB, Palamakumbura AH, Chase HB, Gantz D, Guo Y, Uzel MI, Ma D, Trackman PC. A role for lysyl oxidase regulation in the control of normal collagen deposition in differentiating osteoblast cultures. J Cell Physiol. 2004 Jul; 200(1):53-62. PMID: 15137057

Trackman PC, Kantarci A. Connective tissue metabolism and gingival overgrowth. Crit Rev Oral Biol Med. 2004; 15(3):165-75. PMID: 15187034

Pischon N, Darbois LM, Palamakumbura AH, Kessler E, Trackman PC. Regulation of collagen deposition and lysyl oxidase by tumor necrosis factor-alpha in osteoblasts. J Biol Chem. 2004 Jul 16; 279(29):30060-5. PMID: 15138266

Casavecchia P, Uzel MI, Kantarci A, Hasturk H, Dibart S, Hart TC, Trackman PC, Van Dyke TE. Hereditary gingival fibromatosis associated with generalized aggressive periodontitis: a case report. J Periodontol. 2004 May; 75(5):770-8.View Related Profiles.

Trackman, Philip
Dibart, Serge
Van Dyke, Thomas

PMID: 15212361

Palamakumbura AH, Sommer P, Trackman PC. Autocrine growth factor regulation of lysyl oxidase expression in transformed fibroblasts. J Biol Chem. 2003 Aug 15; 278(33):30781-7. PMID: 12788924

Santana RB, Xu L, Chase HB, Amar S, Graves DT, Trackman PC. A role for advanced glycation end products in diminished bone healing in type 1 diabetes. Diabetes. 2003 Jun; 52(6):1502-10.View Related Profiles.

Trackman, Philip
Amar, Salomon

PMID: 12765963

Harlow CR, Rae M, Davidson L, Trackman PC, Hillier SG. Lysyl oxidase gene expression and enzyme activity in the rat ovary: regulation by follicle-stimulating hormone, androgen, and transforming growth factor-beta superfamily members in vitro. Endocrinology. 2003 Jan; 144(1):154-62. PMID: 12488341

Hong HH, Trackman PC. Cytokine regulation of gingival fibroblast lysyl oxidase, collagen, and elastin. J Periodontol. 2002 Feb; 73(2):145-52. PMID: 11895278

Palamakumbura AH, Trackman PC. A fluorometric assay for detection of lysyl oxidase enzyme activity in biological samples. Anal Biochem. 2002 Jan 15; 300(2):245-51. PMID: 11779117

Uzel MI, Kantarci A, Hong HH, Uygur C, Sheff MC, Firatli E, Trackman PC. Connective tissue growth factor in drug-induced gingival overgrowth. J Periodontol. 2001 Jul; 72(7):921-31. PMID: 11495141

Uzel MI, Scott IC, Babakhanlou-Chase H, Palamakumbura AH, Pappano WN, Hong HH, Greenspan DS, Trackman PC. Multiple bone morphogenetic protein 1-related mammalian metalloproteinases process pro-lysyl oxidase at the correct physiological site and control lysyl oxidase activation in mouse embryo fibroblast cultures. J Biol Chem. 2001 Jun 22; 276(25):22537-43. PMID: 11313359

Uzel MI, Shih SD, Gross H, Kessler E, Gerstenfeld LC, Trackman PC. Molecular events that contribute to lysyl oxidase enzyme activity and insoluble collagen accumulation in osteosarcoma cell clones. J Bone Miner Res. 2000 Jun; 15(6):1189-97.View Related Profiles.

Gerstenfeld, Louis
Trackman, Philip

PMID: 10841188

Hong HH, Uzel MI, Duan C, Sheff MC, Trackman PC. Regulation of lysyl oxidase, collagen, and connective tissue growth factor by TGF-beta1 and detection in human gingiva. Lab Invest. 1999 Dec; 79(12):1655-67. PMID: 10616214

Han XY, Wang W, Komulainen J, Koskinen SO, Kovanen V, Vihko V, Trackman PC, Takala TE. Increased mRNAs for procollagens and key regulating enzymes in rat skeletal muscle following downhill running. Pflugers Arch. 1999 May; 437(6):857-64. PMID: 10370063

Trackman PC, Graham RJ, Bittner HK, Carnes DL, Gilles JA, Graves DT. Inflammation-associated lysyl oxidase protein expression in vivo, and modulation by FGF-2 plus IGF-1. Histochem Cell Biol. 1998 Jul; 110(1):9-14. PMID: 9681684

Feres-Filho EJ, Menassa GB, Trackman PC. Regulation of lysyl oxidase by basic fibroblast growth factor in osteoblastic MC3T3-E1 cells. J Biol Chem. 1996 Mar 15; 271(11):6411-6. PMID: 8626440

Csiszar K, Entersz I, Trackman PC, Samid D, Boyd CD. Functional analysis of the promoter and first intron of the human lysyl oxidase gene. Mol Biol Rep. 1996; 23(2):97-108. PMID: 8983023

Feres-Filho EJ, Choi YJ, Han X, Takala TE, Trackman PC. Pre- and post-translational regulation of lysyl oxidase by transforming growth factor-beta 1 in osteoblastic MC3T3-E1 cells. J Biol Chem. 1995 Dec 22; 270(51):30797-803. PMID: 8530522

Trackman PC, Feres-Filho EJ, Choi YJ. The 3'-untranslated region of rat lysyl oxidase cDNA. Biochim Biophys Acta. 1995 Feb 21; 1260(3):355-60. PMID: 7873615

Sommer P, Gleyzal C, Raccurt M, Delbourg M, Serrar M, Joazeiro P, Peyrol S, Kagan H, Trackman PC, Grimaud JA. Transient expression of lysyl oxidase by liver myofibroblasts in murine schistosomiasis. Lab Invest. 1993 Oct; 69(4):460-70.View Related Profiles.

Kagan, Herbert
Trackman, Philip

PMID: 7901452

Shah MA, Trackman PC, Gallop PM, Kagan HM. Reaction of lysyl oxidase with trans-2-phenylcyclopropylamine. J Biol Chem. 1993 Jun 5; 268(16):11580-5.View Related Profiles.

Kagan, Herbert
Trackman, Philip

PMID: 8099355

Bedell-Hogan D, Trackman P, Abrams W, Rosenbloom J, Kagan H. Oxidation, cross-linking, and insolubilization of recombinant tropoelastin by purified lysyl oxidase. J Biol Chem. 1993 May 15; 268(14):10345-50.View Related Profiles.

Kagan, Herbert
Trackman, Philip

PMID: 8098038

Wu Y, Rich CB, Lincecum J, Trackman PC, Kagan HM, Foster JA. Characterization and developmental expression of chick aortic lysyl oxidase. J Biol Chem. 1992 Dec 5; 267(34):24199-206.View Related Profiles.

Kagan, Herbert
Trackman, Philip

PMID: 1360009

Mariani TJ, Trackman PC, Kagan HM, Eddy RL, Shows TB, Boyd CD, Deak SB. The complete derived amino acid sequence of human lysyl oxidase and assignment of the gene to chromosome 5 (extensive sequence homology with the murine ras recision gene). Matrix. 1992 Jun; 12(3):242-8.View Related Profiles.

Kagan, Herbert
Trackman, Philip

PMID: 1357535

Trackman PC, Bedell-Hogan D, Tang J, Kagan HM. Post-translational glycosylation and proteolytic processing of a lysyl oxidase precursor. J Biol Chem. 1992 Apr 25; 267(12):8666-71.View Related Profiles.

Kagan, Herbert
Trackman, Philip

PMID: 1349020

Kagan HM, Trackman PC. Properties and function of lysyl oxidase. Am J Respir Cell Mol Biol. 1991 Sep; 5(3):206-10.View Related Profiles.

Kagan, Herbert
Trackman, Philip

PMID: 1680355

Trackman PC, Pratt AM, Wolanski A, Tang SS, Offner GD, Troxler RF, Kagan HM. Cloning of rat aorta lysyl oxidase cDNA: complete codons and predicted amino acid sequence. Biochemistry. 1991 Aug 20; 30(33):8282.View Related Profiles.

Offner, Gwynneth
Kagan, Herbert
Trackman, Philip

PMID: 1678281

Kenyon K, Contente S, Trackman PC, Tang J, Kagan HM, Friedman RM. Lysyl oxidase and rrg messenger RNA. Science. 1991 Aug 16; 253(5021):802.View Related Profiles.

Kagan, Herbert
Trackman, Philip

PMID: 1678898

Almassian B, Trackman PC, Iguchi H, Boak A, Calvaresi D, Kagan HM. Induction of lung lysyl oxidase activity and lysyl oxidase protein by exposure of rats to cadmium chloride: properties of the induced enzyme. Connect Tissue Res. 1991; 25(3-4):197-208.View Related Profiles.

Kagan, Herbert
Trackman, Philip

PMID: 1676359

Gacheru SN, Trackman PC, Shah MA, O'Gara CY, Spacciapoli P, Greenaway FT, Kagan HM. Structural and catalytic properties of copper in lysyl oxidase. J Biol Chem. 1990 Nov 5; 265(31):19022-7.View Related Profiles.

Kagan, Herbert
Trackman, Philip

PMID: 1977746

Offner, Gwynneth
Kagan, Herbert
Trackman, Philip

PMID: 1973052

Gacheru SN, Trackman PC, Calaman SD, Greenaway FT, Kagan HM. Vicinal diamines as pyrroloquinoline quinone-directed irreversible inhibitors of lysyl oxidase. J Biol Chem. 1989 Aug 5; 264(22):12963-9.View Related Profiles.

Kagan, Herbert
Trackman, Philip

PMID: 2568990

Gacheru SN, Trackman PC, Kagan HM. Evidence for a functional role for histidine in lysyl oxidase catalysis. J Biol Chem. 1988 Nov 15; 263(32):16704-8.View Related Profiles.

Kagan, Herbert
Trackman, Philip

PMID: 2903154

Ghoda LY, Savarese TM, Dexter DL, Parks RE, Trackman PC, Abeles RH. Characterization of a defect in the pathway for converting 5'-deoxy-5'-methylthioadenosine to methionine in a subline of a cultured heterogeneous human colon carcinoma. J Biol Chem. 1984 Jun 10; 259(11):6715-9. PMID: 6725268

Trackman PC, Abeles RH. Methionine synthesis from 5'-S-Methylthioadenosine. Resolution of enzyme activities and identification of 1-phospho-5-S methylthioribulose. J Biol Chem. 1983 Jun 10; 258(11):6717-20. PMID: 6853500

Tang SS, Trackman PC, Kagan HM. Reaction of aortic lysyl oxidase with beta-aminopropionitrile. J Biol Chem. 1983 Apr 10; 258(7):4331-8.View Related Profiles.

Kagan, Herbert
Trackman, Philip

PMID: 6131892

Trackman PC, Abeles RH. The metabolism of 1-phospho-5-methylthioribose. Biochem Biophys Res Commun. 1981 Dec 31; 103(4):1238-44. PMID: 7037002

Trackman PC, Zoski CG, Kagan HM. Development of a peroxidase-coupled fluorometric assay for lysyl oxidase. Anal Biochem. 1981 May 15; 113(2):336-42.View Related Profiles.

Kagan, Herbert
Trackman, Philip

PMID: 6116464

Kagan HM, Tseng L, Trackman PC, Okamoto K, Rapaka RS, Urry DW. Repeat polypeptide models of elastin as substrates for lysyl oxidase. J Biol Chem. 1980 Apr 25; 255(8):3656-9.View Related Profiles.

Kagan, Herbert
Trackman, Philip

PMID: 6102568

Trackman PC, Kagan HM. Nonpeptidyl amine inhibitors are substrates of lysyl oxidase. J Biol Chem. 1979 Aug 25; 254(16):7831-6.View Related Profiles.

Kagan, Herbert
Trackman, Philip

PMID: 38246

Jordan RE, Milbury P, Sullivan KA, Trackman PC, Kagan HM. Studies on lysyl oxidase of bovine ligamentum nuchae and bovine aorta. Adv Exp Med Biol. 1977; 79:531-42.View Related Profiles.

Kagan, Herbert
Trackman, Philip

PMID: 17272

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 115 publications over 37 distinct years, with a maximum of 7 publications in 2006 and 2007 and 2010 and 2015

Bar chart showing 115 publications over 37 distinct years, with a maximum of 7 publications in 2006 and 2007 and 2010 and 2015

Year	Publications
1980	1
1981	2
1983	2
1984	1
1988	1
1989	1
1990	2
1991	4
1992	3
1993	3
1995	2
1996	2
1998	1
1999	2
2000	1
2001	2
2002	2
2003	3
2004	6
2005	3
2006	7
2007	7
2008	4
2009	3
2010	7
2011	5
2012	2
2013	5
2014	4
2015	7
2016	3
2017	6
2018	3
2019	4
2021	1
2022	1
2023	2