Keywords
Last Name

Shi Yang, MD

TitleAssociate Professor
InstitutionBoston University School of Medicine
DepartmentPathology & Laboratory Medicine
DivisionAnatomic Pathology
Address670 Albany St Biosquare III
Boston MA 02118
Phone(617) 414-5057
ORCID ORCID Icon0000-0001-8316-6484
Other Positions
TitleGraduate Faculty (Primary Mentor of Grad Students)
InstitutionBoston University School of Medicine, Division of Graduate Medical Sciences

 Research Expertise & Professional Interests
Expertise in molecular pathology.

 Self-Described Keywords
  • Association for Molecular pathology
  • Diagnostic Molecular Pathology
  • Molecular Pathology testing
 Publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
List All   |   Timeline
  1. Yang S, Leone D, Frydenlund N, Hoang M, Deng A, Hernandez-Perez M, Biswas A, Singh R, Yaar R, Mahalingam M. Frequency of telomerase reverse transcripter promoter mutations in desmoplastic melanoma subtypes: analyses of 76 cases. Melanoma Res. 2016 Aug; 26(4):361-6. PMID: 27244099.
    View in: PubMed
  2. Kadokura A, Frydenlund N, Leone DA, Yang S, Hoang MP, Deng A, Hernandez-Perez M, Biswas A, Singh R, Yaar R, Mahalingam M. Neurofibromin protein loss in desmoplastic melanoma subtypes: implicating NF1 allelic loss as a distinct genetic driver? Hum Pathol. 2016 Jul; 53:82-90. PMID: 26980030.
    View in: PubMed
  3. Chung HJ, Yang S, Succaria F, Bhawan J. Telomerase (TERT) promoter mutations are infrequent in Merkel cell carcinomas. J Am Acad Dermatol. 2015 Nov; 73(5):864-5. PMID: 26475538.
    View in: PubMed
  4. Frydenlund N, Leone DA, Mitchell B, Yang S, Deng A, Hoang MP, Mahalingam M. Neurotrophin receptors and perineural invasion in desmoplastic melanoma. J Am Acad Dermatol. 2015 May; 72(5):851-8. PMID: 25752716.
    View in: PubMed
  5. Mitchell B, Leone D, Feller JK, Bondzie P, Yang S, Park HY, Mahalingam M. Correlation of chemokine receptor CXCR4 mRNA in primary cutaneous melanoma with established histopathologic prognosticators and the BRAF status. Melanoma Res. 2014 Dec; 24(6):621-5. PMID: 25211166.
    View in: PubMed
  6. O'Brien MJ, Zhao Q, Yang S. Colorectal serrated pathway cancers and precursors. Histopathology. 2015 Jan; 66(1):49-65. PMID: 25263173.
    View in: PubMed
  7. Aung PP, Leone D, Feller JK, Yang S, Hernandez M, Yaar R, Singh R, Helm T, Mahalingam M. Microvessel density, lymphovascular density, and lymphovascular invasion in primary cutaneous melanoma-correlation with histopathologic prognosticators and BRAF status. Hum Pathol. 2015 Feb; 46(2):304-12. PMID: 25537974.
    View in: PubMed
  8. Brogly SB, Perkins RB, Zepf D, Longtine J, Yang S. Human papillomavirus vaccination and cervical cytology in young minority women. Sex Transm Dis. 2014 Aug; 41(8):511-4. PMID: 25013981.
    View in: PubMed
  9. Mitchell B, Leone D, Feller K, Menon S, Bondzie P, Yang S, Park HY, Mahalingam M. Protein expression of the chemokine receptor CXCR4 and its ligand CXCL12 in primary cutaneous melanoma--biomarkers of potential utility? Hum Pathol. 2014 Oct; 45(10):2094-100. PMID: 25130395.
    View in: PubMed
  10. Aung PP, Batrani M, Yang S, Mahalingam M. Apoptosis and in situ and invasive squamous cell carcinoma in sun-exposed sites. Am J Dermatopathol. 2013 Dec; 35(8):797-803. PMID: 23455334.
    View in: PubMed
  11. Zhao Y, Kumbrink J, Lin BT, Bouton AH, Yang S, Toselli PA, Kirsch KH. Expression of a phosphorylated substrate domain of p130Cas promotes PyMT-induced c-Src-dependent murine breast cancer progression. Carcinogenesis. 2013 Dec; 34(12):2880-90. PMID: 23825155.
    View in: PubMed
  12. Feller JK, Yang S, Mahalingam M. Immunohistochemistry with a mutation-specific monoclonal antibody as a screening tool for the BRAFV600E mutational status in primary cutaneous malignant melanoma. Mod Pathol. 2013 Mar; 26(3):414-20. PMID: 23041829.
    View in: PubMed
  13. Park E, Yang S, Emley A, DeCarlo K, Richards J, Mahalingam M. Lack of correlation between immunohistochemical expression of CKIT and KIT mutations in atypical acral nevi. Am J Dermatopathol. 2012 Feb; 34(1):41-6. PMID: 22094233.
    View in: PubMed
  14. Miller DD, Emley A, Yang S, Richards JE, Lee JE, Deng A, Hoang MP, Mahalingam M. Mixed versus pure variants of desmoplastic melanoma: a genetic and immunohistochemical appraisal. Mod Pathol. 2012 Apr; 25(4):505-15. PMID: 22157936.
    View in: PubMed
  15. Emley A, Nguyen LP, Yang S, Mahalingam M. Somatic mutations in GNAQ in amelanotic/hypomelanotic blue nevi. Hum Pathol. 2011 Jan; 42(1):136-40. PMID: 21056896.
    View in: PubMed
  16. Huang CS, Farraye FA, Yang S, O'Brien MJ. The clinical significance of serrated polyps. Am J Gastroenterol. 2011 Feb; 106(2):229-40; quiz 241. PMID: 21045813.
    View in: PubMed
  17. Hetzel JT, Huang CS, Coukos JA, Omstead K, Cerda SR, Yang S, O'Brien MJ, Farraye FA. Variation in the detection of serrated polyps in an average risk colorectal cancer screening cohort. Am J Gastroenterol. 2010 Dec; 105(12):2656-64. PMID: 20717107.
    View in: PubMed
  18. Decarlo K, Yang S, Emley A, Wajapeyee N, Green M, Mahalingam M. Oncogenic BRAF-positive dysplastic nevi and the tumor suppressor IGFBP7--challenging the concept of dysplastic nevi as precursor lesions? Hum Pathol. 2010 Jun; 41(6):886-94. PMID: 20233623.
    View in: PubMed
  19. Emley A, Yang S, Wajapeyee N, Green MR, Mahalingam M. Oncogenic BRAF and the tumor suppressor IGFBP7 in the genesis of atypical spitzoid nevomelanocytic proliferations. J Cutan Pathol. 2010 Mar; 37(3):344-9. PMID: 19788444.
    View in: PubMed
  20. Lee JC, Yang S, Zou Y, Joseph L. Erythroid/B-cell biphenotypic acute leukemia first case report. Leukemia. 2009 Oct; 23(10):1920-3. PMID: 19458630.
    View in: PubMed
  21. Kovacheva VP, Davison JM, Mellott TJ, Rogers AE, Yang S, O'Brien MJ, Blusztajn JK. Raising gestational choline intake alters gene expression in DMBA-evoked mammary tumors and prolongs survival. FASEB J. 2009 Apr; 23(4):1054-63. PMID: 19047067.
    View in: PubMed
  22. Dadzie OE, Yang S, Emley A, Keady M, Bhawan J, Mahalingam M. RAS and RAF mutations in banal melanocytic aggregates contiguous with primary cutaneous melanoma: clues to melanomagenesis. Br J Dermatol. 2009 Feb; 160(2):368-75. PMID: 18945298.
    View in: PubMed
  23. Belguise K, Guo S, Yang S, Rogers AE, Seldin DC, Sherr DH, Sonenshein GE. Green tea polyphenols reverse cooperation between c-Rel and CK2 that induces the aryl hydrocarbon receptor, slug, and an invasive phenotype. Cancer Res. 2007 Dec 15; 67(24):11742-50. PMID: 18089804.
    View in: PubMed
  24. Evolutionary and biomedical insights from the rhesus macaque genome. Science. 2007 Apr 13; 316(5822):222-34. PMID: 17431167.
    View in: PubMed
  25. O'Brien MJ, Yang S, Mack C, Xu H, Huang CS, Mulcahy E, Amorosino M, Farraye FA. Comparison of microsatellite instability, CpG island methylation phenotype, BRAF and KRAS status in serrated polyps and traditional adenomas indicates separate pathways to distinct colorectal carcinoma end points. Am J Surg Pathol. 2006 Dec; 30(12):1491-501. PMID: 17122504.
    View in: PubMed
  26. Sharov AA, Sharova TY, Mardaryev AN, Tommasi di Vignano A, Atoyan R, Weiner L, Yang S, Brissette JL, Dotto GP, Botchkarev VA. Bone morphogenetic protein signaling regulates the size of hair follicles and modulates the expression of cell cycle-associated genes. Proc Natl Acad Sci U S A. 2006 Nov 28; 103(48):18166-71. PMID: 17114283.
    View in: PubMed
  27. Murray SA, Yang S, Demicco E, Ying H, Sherr DH, Hafer LJ, Rogers AE, Sonenshein GE, Xiao ZX. Increased expression of MDM2, cyclin D1, and p27Kip1 in carcinogen-induced rat mammary tumors. J Cell Biochem. 2005 Aug 1; 95(5):875-84. PMID: 15844214.
    View in: PubMed
  28. Huang CS, O'brien MJ, Yang S, Farraye FA. Hyperplastic polyps, serrated adenomas, and the serrated polyp neoplasia pathway. Am J Gastroenterol. 2004 Nov; 99(11):2242-55. PMID: 15555008.
    View in: PubMed
  29. Yang S, Farraye FA, Mack C, Posnik O, O'Brien MJ. BRAF and KRAS Mutations in hyperplastic polyps and serrated adenomas of the colorectum: relationship to histology and CpG island methylation status. Am J Surg Pathol. 2004 Nov; 28(11):1452-9. PMID: 15489648.
    View in: PubMed
  30. O'Brien MJ, Yang S, Clebanoff JL, Mulcahy E, Farraye FA, Amorosino M, Swan N. Hyperplastic (serrated) polyps of the colorectum: relationship of CpG island methylator phenotype and K-ras mutation to location and histologic subtype. Am J Surg Pathol. 2004 Apr; 28(4):423-34. PMID: 15087661.
    View in: PubMed
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