Karen Jacobson | Profiles RNS

Karen R. Jacobson, MD, MPH

Associate Professor

Boston University Chobanian & Avedisian School of Medicine

Medicine

Infectious Diseases

MD, Johns Hopkins University School of Medicine
MPH, Harvard School of Public Health
BS, Yale University

Websites

	Infectious Diseases Faculty
	Boston Medical Center Provider Profile
	Jacobson Research Group
	LinkedIn

ORCID : 0000-0003-4239-3685

Dr. Karen Jacobson is an Associate Professor of Medicine in the Section of Infectious Diseases, Chobanian and Avedisian School of Medicine, with a secondary appointment in the Department of Epidemiology, Boston University School of Public Health. Dr. Jacobson’s research focuses on the epidemiology of tuberculosis, including identification of biological and social determinants of and risk factors for tuberculosis infection and disease (including drug resistant tuberculosis) and approaches for improving tuberculosis outcomes in resource-limited settings. Dr. Jacobson is the Medical Director of the Boston Medical Center Tuberculosis Clinic and has established a highly productive collaboration with researchers in Cape Town, South Africa. Her work has particular emphasis in understanding how substance use impacts on tuberculosis transmission and response to therapy.

Diversity, Equity, Inclusion and Accessibility

I am an infectious disease physician and researcher committed to improving health outcomes for historically underrepresented populations in resource-limited high-burden settings and in our BMC community around Boston.

As a clinician, I serve as the Medical Director of the BMC Tuberculosis (TB) Clinic where I guide and provide direct patient care for a population primarily made up of recent immigrants from many parts of the world. I am part of a group of clinicians committed to offering and
developing standard operating procedures for cutting edge regimens and offering this to all who come for care.

As a researcher, my work focuses on the epidemiology of TB, including identification of biological and social determinants of and risk factors for TB infection and disease and approaches for improving TB outcomes in resource-limited, high-burden settings. Through two ongoing studies based in Worcester, South Africa, my team’s research has been able to investigate the interplay between illicit smoked substances and TB transmission and alcohol use and TB treatment outcomes, focusing on two key populations who are vulnerable to stigma and marginalization. I aim to treat our participants with respect and inclusion and to learn from them as partners.

My commitment to diversity, equity, inclusion and accessibility is visible through my interest in training and mentoring new investigators in our BU/BMC community, including helping trainees and junior faculty identify their own niches and grow a diverse workforce committed to focusing on research that will improve healthcare outcomes and equity.

Associate Professor
Boston University School of Public Health
Epidemiology

Member
Boston University
Evans Center for Interdisciplinary Biomedical Research

Assessing the effects of HIV disease on TB and type 2 diabetes mellitus in a TB patient cohort in Western Cape Province, South Africa
01/01/2021 - 12/31/2021 (Key Person / Mentor)
Providence/Boston Center for AIDS Research NIH NIAID

Using care coordination to support vulnerable patients with risk of Tuberculosis Disease RENEWAL
07/01/2024 - 06/30/2027 (PI)
Massachusetts Dept. of Public Health / DPH

Using care coordination to support vulnerable patients with risk of Tuberculosis Disease
10/01/2023 - 06/30/2026 (PI)
Massachusetts Dept. of Public Health / DPH

Core L - The Providence/Boston Center for AIDS Research (CFAR) competitive renewal
07/01/2023 - 06/30/2026 (Subcontract PI)
PI: Karen R. Jacobson, MD, MPH
The Miriam Hospital NIH NIAID

An RNA nanosensor for the diagnosis of antibiotic resistance in M. tuberculosis
09/13/2023 - 08/31/2025 (Subcontract PI)
PI: Karen R. Jacobson, MD, MPH
Harvard Medical School NIH NIAID
1R01AI176498-01

Administrative Supplement to Transmission Of Tuberculosis Among illicit drug use Linkages (TOTAL)
08/01/2023 - 07/31/2025 (PI)
National Institute of Allergy and Infectious Diseases/NIH/DHHS
5R01AI147316-05

Transmission Of Tuberculosis Among illicit drug use Linkages (TOTAL)
08/01/2019 - 07/31/2025 (PI)
National Institute of Allergy and Infectious Diseases/NIH/DHHS
1R01AI147316-01

Investigating bacterial contributions to TB treatment response: a focus on in-host pathogen dynamics
09/22/2020 - 06/04/2025 (Subcontract PI)
PI: Karen R. Jacobson, MD, MPH
Harvard Medical School NIH NIAID
5R01AI155765-05

Evaluating the tuberculosis epidemic in South Africa using a novel ten year national cohort
04/13/2020 - 03/31/2025 (Multi-PI)
PI: Karen R. Jacobson, MD, MPH
DMMH - A Division of WITS Health Consortium NIH NIAID
1R01AI152126-01

MassCPR COVID biorepository work
10/01/2021 - 12/31/2024 (Subcontract PI)
PI: Karen R. Jacobson, MD, MPH
Harvard Medical School China Evergrande Gr

An RNA Based Phenotypic Assay for the Diagnosis of Antibiotic Resistance in M. Tuberculosis
09/13/2023 - 09/12/2024 (Subcontract PI)
PI: Karen R. Jacobson, MD, MPH
Harvard Medical School NIH NIAID
1R01AI176498-01

Showing 10 of 23 results. Show All Results

Title

Yr	Title	Project-Sub Proj	Pubs
2023	Transmission Of Tuberculosis Among illicit drug use Linkages (TOTAL)	5R01AI147316-05
2022	Transmission Of Tuberculosis Among illicit drug use Linkages (TOTAL)	5R01AI147316-04
2022	SWG1: HIV/TB Scientific Working Group	5P30AI042853-24-7401
2021	Transmission Of Tuberculosis Among illicit drug use Linkages (TOTAL)	5R01AI147316-03
2021	SWG1: HIV/TB Scientific Working Group	5P30AI042853-23-7401	905
2020	Transmission Of Tuberculosis Among illicit drug use Linkages (TOTAL)	5R01AI147316-02
2020	The impact of alcohol consumption on TB treatment outcomes	5R01AI119037-05	3
2020	SWG1: HIV/TB Scientific Working Group	5P30AI042853-22-7401	905
2019	Transmission Of Tuberculosis Among illicit drug use Linkages (TOTAL)	1R01AI147316-01
2019	The impact of alcohol consumption on TB treatment outcomes	5R01AI119037-04	3

Showing 10 of 21 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis Copy PMIDs To Clipboard

Campbell JI, Brooks MB, Dankovchik J, Giebultowicz S, Falkenstein A, Angier H, Horsburgh CR, Tschampl CA, Haberer JE, Bressler J, Epstein RL, Jenkins HE, Jacobson K. Uncovering household tuberculosis infection testing and care patterns using a novel bioinformatics linkage strategy. Clin Infect Dis. 2026 Feb 11.View Related Profiles.

Horsburgh, C.
Jenkins, Helen
Campbell, Jeffrey
Jacobson, Karen
Brooks, Meredith
Epstein, Rachel

PMID: 41668263; DOI: 10.1093/cid/ciag079;

Tabackman A, Acuña-Villaorduña C, Canning M, Karoly M, Dauphinais MR, Michaud R, Bouton TC, Bourque DL, Reifler KA, Sabharwal V, Traber K, Gupte AN, Jacobson KR, Sinha P. Low TB1 and TB2 antigen-nil is associated with increased QuantiFERON Gold Plus reversions. Int J Tuberc Lung Dis. 2026 Jan 30; 30(2):88-89.View Related Profiles.

Gupte, Akshay
Bourque, Daniel
Jacobson, Karen
Reifler, Katherine
Traber, Katrina
Bouton, Tara

PMID: 41618115

Mann BC, Loubser J, Omar S, Glanz C, Ektefaie Y, Jacobson KR, Warren RM, Farhat MR. Systematic review and meta-analysis of protocols and sequencing yield for whole genome sequencing of Mycobacterium tuberculosis directly from sputum samples. Tuberculosis (Edinb). 2026 Mar; 157:102743. PMID: 41633150

Carney T, Mpisane N, Magidson JF, Drainoni ML, Niemand N, Weber S, Meade CS, Jacobson KR, Myers B. "They Call Us Amaphara (Junkies)": Intersectional Tuberculosis, Alcohol, and Drug Stigma in South Africa. Stigma Health. 2025 Dec 15.View Related Profiles.

Jacobson, Karen
Drainoni, Mari-Lynn

PMID: 41693957; PMCID: PMC12900165; DOI: 10.1037/sah0000670;

Malatesta S, Jacobson KR, Horsburgh CR, Farhat M, Carney T, Gile KJ, Kolaczyk ED, White LF. An Integrated Data-Driven Model for Clinical Phenotyping of Tuberculosis Disease Severity. medRxiv. 2025 Nov 27.View Related Profiles.

Horsburgh, C.
Jacobson, Karen
White, Laura

PMID: 41358303; PMCID: PMC12676405; DOI: 10.1101/2025.11.25.25341018;

Wijk M, Denti P, Gausi K, Myers B, Carney T, White LF, Theron D, Parry CDH, Horsburgh CR, Rawoot N, Warren RM, Court R, Kulkarni SG, Farhat MR, Buys C, Malatesta S, Weber SE, Kulkarni S, McIlleron H, Jacobson KR, Kloprogge F. Insights into the Role of Rifampicin Exposure and Clinical Baseline Covariates on the Response to Pulmonary Tuberculosis Treatment. Clin Infect Dis. 2025 Oct 24. PMID: 41133922; DOI: 10.1093/cid/ciaf586;

Malatesta S, Carney T, Niemand Wolhuter N, Overbeck V, Theron D, Weber SE, Meade CS, Thomson S, Bouton TC, Farhat M, Myers B, Wood R, Ratangee F, Horsburgh CR, White LF, Warren RM, Jacobson KR. Tuberculosis Disease Prevalence Among People Who Smoke Illicit Drugs: A Respondent- Driven Sampling Study in the Western Cape, South Africa. J Infect Dis. 2025 Oct 08.View Related Profiles.

Jacobson, Karen
Bouton, Tara

PMID: 41060285; DOI: 10.1093/infdis/jiaf481;

Cohodes M, Fernandez A, Ashkin D, Reed C, Park S, Banaei N, Fung M, Jacobson K, Goswami ND. Curated cases from the TB expert network: Unplugged! Series: Use of plasma microbial cell-free DNA metagenomic sequencing to diagnose Mycobacterium tuberculosis. J Clin Tuberc Other Mycobact Dis. 2025 Dec; 41:100563. PMID: 41049022; PMCID: PMC12495230; DOI: 10.1016/j.jctube.2025.100563;

Niemand N, Rooney JA, Malatesta S, Rawoot N, Bouton TC, Ragan EJ, Carney T, White LF, Farhat M, Horsburgh CR, Myers B, Warren RM, Jacobson KR. Contamination rates in serially sampled sputum specimens obtained during tuberculosis treatment to capture culture conversion. Microbiol Spectr. 2025 Oct 07; 13(10):e0096925.View Related Profiles.

Horsburgh, C.
Jacobson, Karen
White, Laura
Bouton, Tara

PMID: 40879468; PMCID: PMC12502799; DOI: 10.1128/spectrum.00969-25;

Martins MF, Teran Plasencia JM, Jacobson KR, Bouton TC, Traber KE, Canning M, Bourque DL, Sabharwal V, Michaud R, Sinha P, Acuña-Villaorduña CJ. Rifampin versus isoniazid completion rates for TB infection. Int J Tuberc Lung Dis. 2025 Aug 29; 29(9):425-427.View Related Profiles.

Bourque, Daniel
Jacobson, Karen
Traber, Katrina
Sinha, Pranay
Bouton, Tara
Sabharwal, Vishakha

PMID: 40883884; DOI: 10.5588/ijtld.25.0237;

Showing 10 of 103 results. Show More

Tzelios CA, Malatesta S, Carney T, White LF, Weber SE, Thomson S, Theron D, Myers B, Parry CDH, Warren RM, Horsburgh CR, Farhat MR, Jacobson KR. Patient Determinants and Effects on Adherence of Adverse Drug Reactions to Tuberculosis Treatment: A Prospective Cohort Analysis. Clin Infect Dis. 2025 Aug 01; 81(1):167-175.View Related Profiles.

Horsburgh, C.
Jacobson, Karen
White, Laura

PMID: 39973802; PMCID: PMC12314496; DOI: 10.1093/cid/ciae642;

Carney T, Johnson K, Meade C, Niemand N, Rooney J, Weber S, Lambrechts T, Mpisane N, Horsburgh CR, Theron D, Warren R, Thomson S, Overbeck V, Myers B, Jacobson K. The feasibility of respondent-driven sampling with people who use drugs in rural Western Cape, South Africa: A qualitative study. PLOS Glob Public Health. 2025; 5(6):e0004065.View Related Profiles.

Horsburgh, C.
Jacobson, Karen

PMID: 40569934; PMCID: PMC12200662; DOI: 10.1371/journal.pgph.0004065;

Campbell JI, Garing A, Lavache D, Bahad S, Hofman M, Haberer JE, Brooks MB, Sinha P, White LF, Sabharwal V, Tschampl CA, Horsburgh CR, Jenkins HE, Jacobson KR. Social Vulnerability Modifies the Effects of Geographic Proximity on Engagement in Latent Tuberculosis Infection Care in a United States Safety Net Healthcare Network. Open Forum Infect Dis. 2025 Jul; 12(7):ofaf347.View Related Profiles.

Horsburgh, C.
Jenkins, Helen
Campbell, Jeffrey
Jacobson, Karen
White, Laura
Brooks, Meredith
Sinha, Pranay
Bahad, Sophia
Sabharwal, Vishakha

PMID: 40606058; PMCID: PMC12216903; DOI: 10.1093/ofid/ofaf347;

Marin MG, Quinones-Olvera N, Wippel C, Behruznia M, Jeffrey BM, Harris M, Mann BC, Rosenthal A, Jacobson KR, Warren RM, Li H, Meehan CJ, Farhat MR. Pitfalls of bacterial pan-genome analysis approaches: a case study of Mycobacterium tuberculosis and two less clonal bacterial species. Bioinformatics. 2025 May 06; 41(5). PMID: 40341387; PMCID: PMC12119186; DOI: 10.1093/bioinformatics/btaf219;

Thomson SJ, Mistry R, Bayly H, Overbeck V, Sagar M, Schechter-Perkins EM, White LF, Jacobson KR, Bouton TC. Barriers to recruitment of an observational SARS-CoV-2 emergency department cohort at Boston Medical Center. BMC Emerg Med. 2025 Apr 20; 25(1):68.View Related Profiles.

Schechter-Perkins, Elissa
Jacobson, Karen
White, Laura
Sagar, Manish
Bouton, Tara

PMID: 40254607; PMCID: PMC12010546; DOI: 10.1186/s12873-025-01224-w;

Horsburgh, C.
Jacobson, Karen
Bouton, Tara

PMID: 40196277; PMCID: PMC11974994; DOI: 10.1101/2025.03.26.25324668;

Shapiro AN, Moultrie H, Jacobson KR, Bor J, da Silva P, Scott L, Jenkins HE. The risk of rifampicin-resistant TB after drug-susceptible TB treatment. IJTLD Open. 2025 Mar; 2(3):173-175.View Related Profiles.

Jenkins, Helen
Bor, Jacob
Jacobson, Karen

PMID: 40092522; PMCID: PMC11906027; DOI: 10.5588/ijtldopen.24.0552;

Wijk M, Wasmann RE, Jacobson KR, Svensson EM, Denti P. A Pragmatic Approach to Handling Censored Data Below the Lower Limit of Quantification in Pharmacokinetic Modeling. CPT Pharmacometrics Syst Pharmacol. 2025 Jun; 14(6):1042-1049. PMID: 40067154; PMCID: PMC12167912; DOI: 10.1002/psp4.70015;

Mann BC, Loubser J, Omar S, Glanz C, Ektefaie Y, Jacobson KR, Warren RM, Farhat MR. Systematic review and meta-analysis of protocols and yield of direct from sputum sequencing of Mycobacterium tuberculosis. bioRxiv. 2024 Dec 04. PMID: 39677639; PMCID: PMC11642866; DOI: 10.1101/2024.12.04.625621;

Malatesta S, Jacobson KR, Carney T, Kolaczyk ED, Gile KJ, White LF. Inferring bivariate associations with continuous data from studies using respondent-driven sampling. J R Stat Soc Ser C Appl Stat. 2025 Mar; 74(2):429-446.View Related Profiles.

Jacobson, Karen
White, Laura

PMID: 40092669; PMCID: PMC11905883; DOI: 10.1093/jrsssc/qlae061;

Shapiro AN, Scott L, Moultrie H, Jacobson KR, Bor J, Conradie F, da Silva P, Mlisana K, Jenkins HE, Stevens WS. Risk factors for and timing of presumptive recurrent TB. Int J Tuberc Lung Dis. 2024 Nov 01; 28(11):527-533.View Related Profiles.

Jenkins, Helen
Bor, Jacob
Jacobson, Karen

PMID: 39468024

Murnane PM, Afshar M, Chamie G, Cook RL, Ferguson T, Haque LY, Jacobson KR, Justice AC, Kim TW, Khalili M, Krupitsky E, McGinnis KA, Molina P, Muyindike WR, Myers B, Richards VL, So-Armah K, Stewart S, Sulkowski MS, Tien PC, Hahn JA. Using Phosphatidylethanol as an Adjunct to Self-Reported Alcohol Use Improves Identification of Liver Fibrosis Risk. Am J Gastroenterol. 2024 Oct 31; 120(7):1567-1575.View Related Profiles.

So-Armah, Kaku
Jacobson, Karen
Kim, Theresa

PMID: 39480054; PMCID: PMC12041314; DOI: 10.14309/ajg.0000000000003178;

Overbeck V, Malatesta S, Carney T, Myers B, Parry CDH, Horsburgh CR, Theron D, White LF, Warren RM, Jacobson KR, Bouton TC. Understanding the impact of pandemics on long-term medication adherence: directly observed therapy in a tuberculosis treatment cohort pre- and post-COVID-19 lockdowns. BMC Infect Dis. 2024 Oct 14; 24(1):1154.View Related Profiles.

Horsburgh, C.
Jacobson, Karen
White, Laura
Bouton, Tara

PMID: 39396938; PMCID: PMC11475609; DOI: 10.1186/s12879-024-09994-7;

Campbell JI, Lavache D, Garing A, Sabharwal V, Haberer JE, Dubois M, Jenkins HE, Brooks MB, Joseph NT, Kissler K, Horsburgh CR, Jacobson KR. Evaluation of the Tuberculosis Infection Care Cascade Among Pregnant Individuals in a Low-Tuberculosis-Burden Setting. Open Forum Infect Dis. 2024 Sep; 11(9):ofae494.View Related Profiles.

Horsburgh, C.
Jenkins, Helen
Campbell, Jeffrey
Jacobson, Karen
Brooks, Meredith
Joseph, Naima
Sabharwal, Vishakha

PMID: 39238842; PMCID: PMC11376066; DOI: 10.1093/ofid/ofae494;

Ghanem M, Srivastava R, Ektefaie Y, Hoppes D, Rosenfeld G, Yaniv Z, Grinev A, Xu AY, Yang E, Velásquez GE, Harrison L, Rosenthal A, Savic RM, Jacobson KR, Farhat MR. Percent of lung involved in disease on chest X-ray predicts unfavorable treatment outcome in pulmonary tuberculosis. medRxiv. 2024 Aug 20. PMID: 39228708; PMCID: PMC11370523; DOI: 10.1101/2024.08.19.24311411;

Kulkarni S, Weber SE, Buys C, Lambrechts T, Myers B, Drainoni ML, Jacobson KR, Theron D, Carney T. Patient and provider perceptions of the relationship between alcohol use and TB and readiness for treatment: a qualitative study in South Africa. BMC Public Health. 2024 Aug 14; 24(1):2216.View Related Profiles.

Jacobson, Karen
Drainoni, Mari-Lynn

PMID: 39143513; PMCID: PMC11325746; DOI: 10.1186/s12889-024-19570-y;

Wijk M, Gausi K, Malatesta S, Weber SE, Court R, Myers B, Carney T, Parry CDH, Horsburgh CR, White LF, Wiesner L, Warren RM, Uren C, McIlleron H, Kloprogge F, Denti P, Jacobson KR. The impact of alcohol and illicit substance use on the pharmacokinetics of first-line TB drugs. J Antimicrob Chemother. 2024 Aug 01; 79(8):2022-2030.View Related Profiles.

Horsburgh, C.
Jacobson, Karen
White, Laura

PMID: 38985541; PMCID: PMC11290884; DOI: 10.1093/jac/dkae206;

Savinkina A, Muyindike W, Hahn JA, Emenyonu NI, Fatch R, Ngabirano C, Adong J, Jacobson KR, Linas BP. Strategies for isoniazid preventive therapy in HIV-positive patients who consume alcohol. Int J Tuberc Lung Dis. 2024 Jul 01; 28(7):335-342.View Related Profiles.

Linas, Benjamin
Jacobson, Karen

PMID: 38961548; PMCID: PMC11875055; DOI: 10.5588/ijtld.23.0303;

Farhat MR, Jacobson KR. For Tuberculosis, Not "To Screen or Not to Screen?" but "Who?" and "How?". Clin Infect Dis. 2024 Jun 14; 78(6):1677-1679. PMID: 38636953; PMCID: PMC11175681; DOI: 10.1093/cid/ciae058;

Marin MG, Wippel C, Quinones-Olvera N, Behruznia M, Jeffrey BM, Harris M, Mann BC, Rosenthal A, Jacobson KR, Warren RM, Li H, Meehan CJ, Farhat MR. Analysis of the limited M. tuberculosis accessory genome reveals potential pitfalls of pan-genome analysis approaches. bioRxiv. 2024 Mar 25. PMID: 38585972; PMCID: PMC10996470; DOI: 10.1101/2024.03.21.586149;

Shapiro AN, Scott L, Moultrie H, Jacobson KR, Bor J, Fofana AM, Dor G, Ndjeka NO, da Silva P, Mlisana K, Jenkins HE, Stevens WS. Tuberculosis testing patterns in South Africa to identify groups that would benefit from increased investigation. Sci Rep. 2023 Nov 27; 13(1):20875.View Related Profiles.

Jenkins, Helen
Bor, Jacob
Jacobson, Karen

PMID: 38012266; PMCID: PMC10682361; DOI: 10.1038/s41598-023-47148-y;

Scott LE, Shapiro AN, Da Silva MP, Tsoka J, Jacobson KR, Emch M, Moultrie H, Jenkins HE, Moore D, Van Rie A, Stevens WS. Integrating Molecular Diagnostics and GIS Mapping: A Multidisciplinary Approach to Understanding Tuberculosis Disease Dynamics in South Africa Using Xpert MTB/RIF. Diagnostics (Basel). 2023 Oct 10; 13(20).View Related Profiles.

Jenkins, Helen
Jacobson, Karen

PMID: 37891984; PMCID: PMC10606157; DOI: 10.3390/diagnostics13203163;

Jacobson, Karen
Drainoni, Mari-Lynn

PMID: 37841852; PMCID: PMC10571641; DOI: 10.21203/rs.3.rs-3290185/v1;

Mann BC, Jacobson KR, Ghebrekristos Y, Warren RM, Farhat MR. Assessment and validation of enrichment and target capture approaches to improve Mycobacterium tuberculosis WGS from direct patient samples. J Clin Microbiol. 2023 Oct 24; 61(10):e0038223. PMID: 37728909; PMCID: PMC10595060; DOI: 10.1128/jcm.00382-23;

Acuña-Villaorduña C, Jacobson KR, Horsburgh CR, Canning M, Sinha P. Initial experience with BPaL-based regimens to treat multidrug-resistant TB. Int J Tuberc Lung Dis. 2023 Aug 01; 27(8):649-650.View Related Profiles.

Jacobson, Karen
Sinha, Pranay

PMID: 37491751; PMCID: PMC10365559; DOI: 10.5588/ijtld.23.0185;

Esmail H, Coussens AK, Thienemann F, Sossen B, Mukasa SL, Warwick J, Goliath RT, Davies NO, Douglass E, Jackson A, Lakay F, Streicher E, Munro JE, Barrios MH, Heinsohn T, Macpherson L, Sheerin D, Aziz S, Serole K, Daroowala R, Taliep A, Ahlers P, Malherbe ST, Bowden R, Warren R, Walzl G, Via LE, Bahlo M, Jacobson KR, Horsburgh CR, Salgame P, Alland D, Barry CE, Flynn JL, Ellner JJ, Wilkinson RJ. High resolution imaging and five-year tuberculosis contact outcomes. medRxiv. 2023 Jul 03. PMID: 37461515; PMCID: PMC10350144; DOI: 10.1101/2023.07.03.23292111;

Myers B, Carney T, Rooney J, Malatesta S, Ragan EJ, White LF, Natcheva H, Bouton TC, Weber SE, Farhat M, McIlleron H, Theron D, Parry CDH, Horsburgh CR, Warren RM, Jacobson KR. Smoked drug use in patients with TB is associated with higher bacterial burden. Int J Tuberc Lung Dis. 2023 Jun 01; 27(6):444-450.View Related Profiles.

Jacobson, Karen
White, Laura
Bouton, Tara

PMID: 37231597; PMCID: PMC10407961; DOI: 10.5588/ijtld.22.0650;

Hahn JA, Ngabirano C, Fatch R, Emenyonu NI, Cheng DM, Adong J, Tumwegamire A, Terrault NA, Linas BP, Jacobson KR, Muyindike WR. Safety and tolerability of isoniazid preventive therapy for tuberculosis for persons with HIV with and without alcohol use. AIDS. 2023 Aug 01; 37(10):1535-1543.View Related Profiles.

Linas, Benjamin
Cheng, Debbie
Jacobson, Karen

PMID: 37260251; PMCID: PMC10355800; DOI: 10.1097/QAD.0000000000003613;

Adeoye B, Nakiyingi L, Moreau Y, Nankya E, Olson AJ, Zhang M, Jacobson KR, Gupta A, Manabe YC, Hosseinipour MC, Kumwenda J, Sagar M. Mycobacterium tuberculosis disease associates with higher HIV-1-specific antibody responses. iScience. 2023 May 19; 26(5):106631.View Related Profiles.

Olson, Alex
Jacobson, Karen
Sagar, Manish

PMID: 37168567; PMCID: PMC10165194; DOI: 10.1016/j.isci.2023.106631;

Sinha P, Jacobson KR, Horsburgh CR, Acuña-Villaorduña C. At Long Last: Short, All-Oral Regimens for Multidrug-Resistant Tuberculosis in the United States. Open Forum Infect Dis. 2023 Apr; 10(4):ofad177.View Related Profiles.

Horsburgh, C.
Jacobson, Karen
Sinha, Pranay

PMID: 37125228; PMCID: PMC10135426; DOI: 10.1093/ofid/ofad177;

Fofana AM, Moultrie H, Scott L, Jacobson KR, Shapiro AN, Dor G, Crankshaw B, Silva PD, Jenkins HE, Bor J, Stevens WS. Cross-municipality migration and spread of tuberculosis in South Africa. Sci Rep. 2023 Feb 15; 13(1):2674.View Related Profiles.

Jenkins, Helen
Bor, Jacob
Jacobson, Karen

PMID: 36792792; PMCID: PMC9930008; DOI: 10.1038/s41598-023-29804-5;

Bouton TC, Atarere J, Turcinovic J, Seitz S, Sher-Jan C, Gilbert M, White L, Zhou Z, Hossain MM, Overbeck V, Doucette-Stamm L, Platt J, Landsberg HE, Hamer DH, Klapperich C, Jacobson KR, Connor JH. Viral Dynamics of Omicron and Delta Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Variants With Implications for Timing of Release from Isolation: A Longitudinal Cohort Study. Clin Infect Dis. 2023 Feb 08; 76(3):e227-e233.View Related Profiles.

Klapperich, Catherine
Hamer, Davidson
Connor, John
Platt, Judy
Jacobson, Karen
White, Laura
Seitz, Scott
Bouton, Tara

PMID: 35737948; PMCID: PMC9278204; DOI: 10.1093/cid/ciac510;

Petros BA, Turcinovic J, Welch NL, White LF, Kolaczyk ED, Bauer MR, Cleary M, Dobbins ST, Doucette-Stamm L, Gore M, Nair P, Nguyen TG, Rose S, Taylor BP, Tsang D, Wendlandt E, Hope M, Platt JT, Jacobson KR, Bouton T, Yune S, Auclair JR, Landaverde L, Klapperich CM, Hamer DH, Hanage WP, MacInnis BL, Sabeti PC, Connor JH, Springer M. Early Introduction and Rise of the Omicron Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Variant in Highly Vaccinated University Populations. Clin Infect Dis. 2023 Feb 08; 76(3):e400-e408.View Related Profiles.

Klapperich, Catherine
Hamer, Davidson
Connor, John
Platt, Judy
Jacobson, Karen
White, Laura
Bouton, Tara

PMID: 35616119; PMCID: PMC9213864; DOI: 10.1093/cid/ciac413;

Muyindike WR, Fatch R, Cheng DM, Emenyonu NI, Forman L, Ngabirano C, Adong J, Linas B, Jacobson KR, Hahn JA. Unhealthy Alcohol Use Is Associated With Suboptimal Adherence to Isoniazid Preventive Therapy in Persons With HIV in Southwestern Uganda. J Acquir Immune Defic Syndr. 2022 Dec 15; 91(5):460-468.View Related Profiles.

Linas, Benjamin
Cheng, Debbie
Jacobson, Karen

PMID: 36044285; PMCID: PMC9649866; DOI: 10.1097/QAI.0000000000003082;

Malatesta S, Weir IR, Weber SE, Bouton TC, Carney T, Theron D, Myers B, Horsburgh CR, Warren RM, Jacobson KR, White LF. Methods for handling missing data in serially sampled sputum specimens for mycobacterial culture conversion calculation. BMC Med Res Methodol. 2022 Nov 19; 22(1):297.View Related Profiles.

Jacobson, Karen
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Forman LS, Lodi S, Fatch R, Emenyonu NI, Adong J, Ngabirano C, Jacobson KR, Gerona R, Reckers AR, Gandhi M, Muyindike WR, Hahn JA. Agreement Between Measures of Adherence to Isoniazid Preventive Therapy Among People With HIV in Uganda. Open Forum Infect Dis. 2022 Oct; 9(10):ofac516.View Related Profiles.

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Barocas JA, Savinkina A, Lodi S, Epstein RL, Bouton TC, Sperring H, Hsu HE, Jacobson KR, Schechter-Perkins EM, Linas BP, White LF. Projected Long-Term Impact of the Coronavirus Disease 2019 (COVID-19) Pandemic on Hepatitis C Outcomes in the United States: A Modeling Study. Clin Infect Dis. 2022 Aug 24; 75(1):e1112-e1119.View Related Profiles.

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Sy KTL, Leavitt SV, de Vos M, Dolby T, Bor J, Horsburgh CR, Warren RM, Streicher EM, Jenkins HE, Jacobson KR. Spatial heterogeneity of extensively drug resistant-tuberculosis in Western Cape Province, South Africa. Sci Rep. 2022 Jun 27; 12(1):10844.View Related Profiles.

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Wigger GW, Bouton TC, Jacobson KR, Auld SC, Yeligar SM, Staitieh BS. The Impact of Alcohol Use Disorder on Tuberculosis: A Review of the Epidemiology and Potential Immunologic Mechanisms. Front Immunol. 2022; 13:864817.View Related Profiles.

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Carney T, Rooney JA, Niemand N, Myers B, Theron D, Wood R, White LF, Meade CS, Chegou NN, Ragan E, Walzl G, Horsburgh R, Warren RM, Jacobson KR. Transmission Of Tuberculosis Among illicit drug use Linkages (TOTAL): A cross-sectional observational study protocol using respondent driven sampling. PLoS One. 2022; 17(2):e0262440.View Related Profiles.

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Hu Z, van der Ploeg K, Chakraborty S, Arunachalam P, Mori D, Jacobson K, Bonilla H, Parsonnet J, Andrews J, Hedlin H, de la Parte L, Dantzler K, Ty M, Tan G, Blish C, Takahashi S, Rodriguez-Barraquer I, Greenhouse B, Butte A, Singh U, Pulendran B, Wang T, Jagannathan P. Early immune responses have long-term associations with clinical, virologic, and immunologic outcomes in patients with COVID-19. Res Sq. 2022 Feb 02. PMID: 35132407; PMCID: PMC8820672; DOI: 10.21203/rs.3.rs-847082/v1;

Ragan EJ, McCallum C, Marathe J, Cole M, Hofman M, Henderson AJ, Flack T, Miller NS, Burks EJ, Zhao GQ, Denis R, Lin NH, Jacobson KR, Andry CD, Pelton SI, Duffy ER, Bhadelia N. Pandemic Response Requires Research Samples: A U.S. Safety-Net Hospital's Experience and Call for National Action. Ann Intern Med. 2021 12; 174(12):1727-1732.View Related Profiles.

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Bouton TC, Lodi S, Turcinovic J, Schaeffer B, Weber SE, Quinn E, Korn C, Steiner J, Schechter-Perkins EM, Duffy E, Ragan EJ, Taylor BP, Miller N, Davidoff R, Hanage WP, Connor J, Pierre C, Jacobson KR. Coronavirus Disease 2019 Vaccine Impact on Rates of Severe Acute Respiratory Syndrome Coronavirus 2 Cases and Postvaccination Strain Sequences Among Health Care Workers at an Urban Academic Medical Center: A Prospective Cohort Study. Open Forum Infect Dis. 2021 Oct; 8(10):ofab465.View Related Profiles.

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Berhanu RH, Jacobson KR. Tuberculosis Preventive Therapy for People With HIV Infection in High Tuberculosis Burden Settings: How Much Is Enough? Ann Intern Med. 2021 10; 174(10):1462-1463.View Related Profiles.

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Freiman JM, Fatch R, Cheng D, Emenyonu N, Ngabirano C, Geadas C, Adong J, Muyindike WR, Linas BP, Jacobson KR, Hahn JA. Prevalence of elevated liver transaminases and their relationship with alcohol use in people living with HIV on anti-retroviral therapy in Uganda. PLoS One. 2021; 16(6):e0250368.View Related Profiles.

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Hahn JA, Murnane PM, Vittinghoff E, Muyindike WR, Emenyonu NI, Fatch R, Chamie G, Haberer JE, Francis JM, Kapiga S, Jacobson K, Myers B, Couture MC, DiClemente RJ, Brown JL, So-Armah K, Sulkowski M, Marcus GM, Woolf-King S, Cook RL, Richards VL, Molina P, Ferguson T, Welsh D, Piano MR, Phillips SA, Stewart S, Afshar M, Page K, McGinnis K, Fiellin DA, Justice AC, Bryant K, Saitz R. Factors associated with phosphatidylethanol (PEth) sensitivity for detecting unhealthy alcohol use: An individual patient data meta-analysis. Alcohol Clin Exp Res. 2021 06; 45(6):1166-1187.View Related Profiles.

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Kataria Y, Cole M, Duffy E, de la Cena K, Schechter-Perkins EM, Bouton TC, Werler MM, Pierre C, Ragan EJ, Weber SE, Jacobson KR, Andry C. Seroprevalence of SARS-CoV-2 IgG antibodies and risk factors in health care workers at an academic medical center in Boston, Massachusetts. Sci Rep. 2021 05 06; 11(1):9694.View Related Profiles.

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Bouton TC, Lodi S, Turcinovic J, Weber SE, Quinn E, Korn C, Steiner J, Schechter-Perkins EM, Duffy E, Ragan EJ, Taylor BP, Schaeffer B, Miller N, Davidoff R, Hanage WP, Connor J, Pierre C, Jacobson KR. COVID-19 vaccine impact on rates of SARS-CoV-2 cases and post vaccination strain sequences among healthcare workers at an urban academic medical center: a prospective cohort study. medRxiv. 2021 Mar 31.View Related Profiles.

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Barocas JA, Jacobson KR, Hamer DH. Addressing the COVID-19 Pandemic Among Persons Experiencing Homelessness: Steps to Protect a Vulnerable Population. J Gen Intern Med. 2021 05; 36(5):1416-1417.View Related Profiles.

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Leavitt SV, Jacobson KR, Ragan EJ, Bor J, Hughes J, Bouton TC, Dolby T, Warren RM, Jenkins HE. Decentralized Care for Rifampin-Resistant Tuberculosis, Western Cape, South Africa. Emerg Infect Dis. 2021; 27(3):728-739.View Related Profiles.

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Kan CK, Ragan EJ, Sarkar S, Knudsen S, Forsyth M, Muthuraj M, Vinod K, Jenkins HE, Horsburgh CR, Salgame P, Roy G, Ellner JJ, Jacobson KR, Sahu S, Hochberg NS. Alcohol use and tuberculosis clinical presentation at the time of diagnosis in Puducherry and Tamil Nadu, India. PLoS One. 2020; 15(12):e0240595.View Related Profiles.

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He X, Eddy JJ, Jacobson KR, Henderson AJ, Agosto LM. Enhanced Human Immunodeficiency Virus-1 Replication in CD4+ T Cells Derived From Individuals With Latent Mycobacterium tuberculosis Infection. J Infect Dis. 2020 10 01; 222(9):1550-1560.View Related Profiles.

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Eddy JJ, Gadani KM, Tibbs A, Bernardo J, Cochran J, White LF, Horsburgh CR, Jacobson KR. Increasing Drug Resistance Among Persons With Tuberculosis in Massachusetts, 2009-2018. Open Forum Infect Dis. 2020 Aug; 7(8):ofaa300.View Related Profiles.

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Hsu HE, Ashe EM, Silverstein M, Hofman M, Lange SJ, Razzaghi H, Mishuris RG, Davidoff R, Parker EM, Penman-Aguilar A, Clarke KEN, Goldman A, James TL, Jacobson K, Lasser KE, Xuan Z, Peacock G, Dowling NF, Goodman AB. Race/Ethnicity, Underlying Medical Conditions, Homelessness, and Hospitalization Status of Adult Patients with COVID-19 at an Urban Safety-Net Medical Center - Boston, Massachusetts, 2020. MMWR Morb Mortal Wkly Rep. 2020 Jul 10; 69(27):864-869.View Related Profiles.

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Muyindike WR, Fatch R, Cheng DM, Emenyonu NI, Ngabirano C, Adong J, Linas BP, Jacobson KR, Hahn JA. Tuberculin skin test positivity among HIV-infected alcohol drinkers on antiretrovirals in south-western Uganda. PLoS One. 2020; 15(7):e0235261.View Related Profiles.

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Ragan EJ, Kleinman MB, Sweigart B, Gnatienko N, Parry CD, Horsburgh CR, LaValley MP, Myers B, Jacobson KR. The impact of alcohol use on tuberculosis treatment outcomes: a systematic review and meta-analysis. Int J Tuberc Lung Dis. 2020 01 01; 24(1):73-82.View Related Profiles.

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Bouton TC, de Vos M, Ragan EJ, White LF, Van Zyl L, Theron D, Horsburgh CR, Warren RM, Jacobson KR. Switching to bedaquiline for treatment of rifampicin-resistant tuberculosis in South Africa: A retrospective cohort analysis. PLoS One. 2019; 14(10):e0223308.View Related Profiles.

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Bulabula ANH, Nelson JA, Musafiri EM, Machekano R, Sam-Agudu NA, Diacon AH, Shah M, Creswell J, Theron G, Warren RM, Jacobson KR, Chirambiza JP, Kalumuna D, Bisimwa BC, Katoto PDMC, Kaswa MK, Birembano FM, Kitete L, Grobusch MP, Kashongwe ZM, Nachega JB. Prevalence, Predictors, and Successful Treatment Outcomes of Xpert MTB/RIF-identified Rifampicin-resistant Tuberculosis in Post-conflict Eastern Democratic Republic of the Congo, 2012-2017: A Retrospective Province-Wide Cohort Study. Clin Infect Dis. 2019 09 27; 69(8):1278-1287. PMID: 30759187; PMCID: PMC6763636; DOI: 10.1093/cid/ciy1105;

van der Heijden YF, Hughes J, Dowdy DW, Streicher E, Chihota V, Jacobson KR, Warren R, Theron G. Overcoming limitations of tuberculosis information systems: researcher and clinician perspectives. Public Health Action. 2019 Sep 21; 9(3):120-127. PMID: 31803584; PMCID: PMC6827492; DOI: 10.5588/pha.19.0014;

Bouton TC, Forson A, Kudzawu S, Zigah F, Jenkins H, Bamfo TD, Carter J, Jacobson K, Kwara A. High mortality during tuberculosis retreatment at a Ghanaian tertiary center: a retrospective cohort study. Pan Afr Med J. 2019; 33:111.View Related Profiles.

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Berhanu RH, Schnippel K, Kularatne R, Firnhaber C, Jacobson KR, Horsburgh CR, Lippincott CK. Discordant rifampicin susceptibility results are associated with Xpert® MTB/RIF probe B and probe binding delay. Int J Tuberc Lung Dis. 2019 03 01; 23(3):358-362.View Related Profiles.

Horsburgh, C.
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Olson A, Ragan EJ, Nakiyingi L, Lin N, Jacobson KR, Ellner JJ, Manabe YC, Sagar M. Brief Report: Pulmonary Tuberculosis Is Associated With Persistent Systemic Inflammation and Decreased HIV-1 Reservoir Markers in Coinfected Ugandans. J Acquir Immune Defic Syndr. 2018 11 01; 79(3):407-411.View Related Profiles.

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Myers B, Bouton TC, Ragan EJ, White LF, McIlleron H, Theron D, Parry CDH, Horsburgh CR, Warren RM, Jacobson KR. Impact of alcohol consumption on tuberculosis treatment outcomes: a prospective longitudinal cohort study protocol. BMC Infect Dis. 2018 Sep 29; 18(1):488.View Related Profiles.

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McIntosh AI, Jenkins HE, White LF, Barnard M, Thomson DR, Dolby T, Simpson J, Streicher EM, Kleinman MB, Ragan EJ, van Helden PD, Murray MB, Warren RM, Jacobson KR. Using routinely collected laboratory data to identify high rifampicin-resistant tuberculosis burden communities in the Western Cape Province, South Africa: A retrospective spatiotemporal analysis. PLoS Med. 2018 08; 15(8):e1002638.View Related Profiles.

Jenkins, Helen
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PMID: 30130377; PMCID: PMC6103505; DOI: 10.1371/journal.pmed.1002638;

Berhanu RH, Schnippel K, Kularatne R, Firnhaber C, Jacobson KR, Horsburgh CR, Lippincott CK. Can patients afford the cost of treatment for multidrug-resistant tuberculosis in Ethiopia? Int J Tuberc Lung Dis. 2018 08 01; 22(8):358-362.View Related Profiles.

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Geadas C, Acuna-Villaorduna C, Mercier G, Kleinman MB, Horsburgh CR, Ellner JJ, Jacobson KR. FDG-PET/CT activity leads to the diagnosis of unsuspected TB: a retrospective study. BMC Res Notes. 2018 Jul 13; 11(1):464.View Related Profiles.

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PMID: 30001743; PMCID: PMC6044021; DOI: 10.1186/s13104-018-3564-6;

Fregonese F, Ahuja SD, Akkerman OW, Arakaki-Sanchez D, Ayakaka I, Baghaei P, Bang D, Bastos M, Benedetti A, Bonnet M, Cattamanchi A, Cegielski P, Chien JY, Cox H, Dedicoat M, Erkens C, Escalante P, Falzon D, Garcia-Prats AJ, Gegia M, Gillespie SH, Glynn JR, Goldberg S, Griffith D, Jacobson KR, Johnston JC, Jones-López EC, Khan A, Koh WJ, Kritski A, Lan ZY, Lee JH, Li PZ, Maciel EL, Galliez RM, Merle CSC, Munang M, Narendran G, Nguyen VN, Nunn A, Ohkado A, Park JS, Phillips PPJ, Ponnuraja C, Reves R, Romanowski K, Seung K, Schaaf HS, Skrahina A, Soolingen DV, Tabarsi P, Trajman A, Trieu L, Banurekha VV, Viiklepp P, Wang JY, Yoshiyama T, Menzies D. Comparison of different treatments for isoniazid-resistant tuberculosis: an individual patient data meta-analysis. Lancet Respir Med. 2018 04; 6(4):265-275. PMID: 29595509; PMCID: PMC9017096; DOI: 10.1016/S2213-2600(18)30078-X;

Freiman JM, Jacobson KR, Muyindike WR, Horsburgh CR, Ellner JJ, Hahn JA, Linas BP. Isoniazid Preventive Therapy for People With HIV Who Are Heavy Alcohol Drinkers in High TB-/HIV-Burden Countries: A Risk-Benefit Analysis. J Acquir Immune Defic Syndr. 2018 04 01; 77(4):405-412.View Related Profiles.

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PMID: 29239900; PMCID: PMC5825241; DOI: 10.1097/QAI.0000000000001610;

Brooks-Pollock E, Jacobson KR. Rethinking tuberculosis control by targeting previously treated individuals. Lancet Glob Health. 2018 04; 6(4):e361-e362. PMID: 29472017

Farhat MR, Jacobson KR, Franke MF, Kaur D, Murray M, Mitnick CD. Fluoroquinolone Resistance Mutation Detection Is Equivalent to Culture-Based Drug Sensitivity Testing for Predicting Multidrug-Resistant Tuberculosis Treatment Outcome: A Retrospective Cohort Study. Clin Infect Dis. 2017 Oct 15; 65(8):1364-1370. PMID: 29017248; PMCID: PMC5850426; DOI: 10.1093/cid/cix556;

Jacobson KR, Barnard M, Kleinman MB, Streicher EM, Ragan EJ, White LF, Shapira O, Dolby T, Simpson J, Scott L, Stevens W, van Helden PD, Van Rie A, Warren RM. Implications of Failure to Routinely Diagnose Resistance to Second-Line Drugs in Patients With Rifampicin-Resistant Tuberculosis on Xpert MTB/RIF: A Multisite Observational Study. Clin Infect Dis. 2017 Jun 01; 64(11):1502-1508.View Related Profiles.

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PMID: 28199520; PMCID: PMC5434334; DOI: 10.1093/cid/cix128;

Jacobson KR. Tuberculosis. Ann Intern Med. 2017 Feb 07; 166(3):ITC17-ITC32. PMID: 28166561; DOI: 10.7326/AITC201702070;

Farhat MR, Sultana R, Iartchouk O, Bozeman S, Galagan J, Sisk P, Stolte C, Nebenzahl-Guimaraes H, Jacobson K, Sloutsky A, Kaur D, Posey J, Kreiswirth BN, Kurepina N, Rigouts L, Streicher EM, Victor TC, Warren RM, van Soolingen D, Murray M. Genetic Determinants of Drug Resistance in Mycobacterium tuberculosis and Their Diagnostic Value. Am J Respir Crit Care Med. 2016 Sep 01; 194(5):621-30.View Related Profiles.

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PMID: 26910495; PMCID: PMC5027209; DOI: 10.1164/rccm.201510-2091OC;

Farhat MR, Jacobson KR, Franke MF, Kaur D, Sloutsky A, Mitnick CD, Murray M. Gyrase Mutations Are Associated with Variable Levels of Fluoroquinolone Resistance in Mycobacterium tuberculosis. J Clin Microbiol. 2016 Mar; 54(3):727-33. PMID: 26763957; PMCID: PMC4767988; DOI: 10.1128/JCM.02775-15;

Jacobson KR, Sabin LL. Scaling up multidrug-resistant tuberculosis care in China. Lancet Glob Health. 2015 Apr; 3(4):e183-4.View Related Profiles.

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Farhat MR, Mitnick CD, Franke MF, Kaur D, Sloutsky A, Murray M, Jacobson KR. Concordance of Mycobacterium tuberculosis fluoroquinolone resistance testing: implications for treatment. Int J Tuberc Lung Dis. 2015 Mar; 19(3):339-41. PMID: 25686144; PMCID: PMC4486051; DOI: 10.5588/ijtld.14.0814;

Kendall EA, Theron D, Franke MF, van Helden P, Victor TC, Murray MB, Warren RM, Jacobson KR. Alcohol, hospital discharge, and socioeconomic risk factors for default from multidrug resistant tuberculosis treatment in rural South Africa: a retrospective cohort study. PLoS One. 2013; 8(12):e83480. PMID: 24349518; PMCID: PMC3862731; DOI: 10.1371/journal.pone.0083480;

Nebenzahl-Guimaraes H, Jacobson KR, Farhat MR, Murray MB. Systematic review of allelic exchange experiments aimed at identifying mutations that confer drug resistance in Mycobacterium tuberculosis. J Antimicrob Chemother. 2014 Feb; 69(2):331-42. PMID: 24055765; PMCID: PMC3886931; DOI: 10.1093/jac/dkt358;

Farhat MR, Shapiro BJ, Kieser KJ, Sultana R, Jacobson KR, Victor TC, Warren RM, Streicher EM, Calver A, Sloutsky A, Kaur D, Posey JE, Plikaytis B, Oggioni MR, Gardy JL, Johnston JC, Rodrigues M, Tang PK, Kato-Maeda M, Borowsky ML, Muddukrishna B, Kreiswirth BN, Kurepina N, Galagan J, Gagneux S, Birren B, Rubin EJ, Lander ES, Sabeti PC, Murray M. Genomic analysis identifies targets of convergent positive selection in drug-resistant Mycobacterium tuberculosis. Nat Genet. 2013 Oct; 45(10):1183-9.View Related Profiles.

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Jacobson KR, Theron D, Kendall EA, Franke MF, Barnard M, van Helden PD, Victor TC, Streicher EM, Murray MB, Warren RM. Implementation of genotype MTBDRplus reduces time to multidrug-resistant tuberculosis therapy initiation in South Africa. Clin Infect Dis. 2013 Feb; 56(4):503-8. PMID: 23090928; PMCID: PMC3552527; DOI: 10.1093/cid/cis920;

Mukinda FK, Theron D, van der Spuy GD, Jacobson KR, Roscher M, Streicher EM, Musekiwa A, Coetzee GJ, Victor TC, Marais BJ, Nachega JB, Warren RM, Schaaf HS. Rise in rifampicin-monoresistant tuberculosis in Western Cape, South Africa. Int J Tuberc Lung Dis. 2012 Feb; 16(2):196-202. PMID: 22236920; PMCID: PMC3712259; DOI: 10.5588/ijtld.11.0116;

Jacobson KR, Theron D, Victor TC, Streicher EM, Warren RM, Murray MB. Treatment outcomes of isoniazid-resistant tuberculosis patients, Western Cape Province, South Africa. Clin Infect Dis. 2011 Aug; 53(4):369-72. PMID: 21810750; PMCID: PMC3202325; DOI: 10.1093/cid/cir406;

Wang HE, Mann NC, Mears G, Jacobson K, Yealy DM. Out-of-hospital airway management in the United States. Resuscitation. 2011 Apr; 82(4):378-85. PMID: 21288624; DOI: 10.1016/j.resuscitation.2010.12.014;

Jacobson KR, Tierney DB, Jeon CY, Mitnick CD, Murray MB. Treatment outcomes among patients with extensively drug-resistant tuberculosis: systematic review and meta-analysis. Clin Infect Dis. 2010 Jul 1; 51(1):6-14. PMID: 20504231; PMCID: PMC4013786; DOI: 10.1086/653115;

Jacobson KR, Murray K, Zellos A, Schwarz KB. An analysis of published trials of interferon monotherapy in children with chronic hepatitis C. J Pediatr Gastroenterol Nutr. 2002 Jan; 34(1):52-8. PMID: 11753165

Altemus M, Greenberg BD, Keuler D, Jacobson KR, Murphy DL. Open trial of flutamide for treatment of obsessive-compulsive disorder. J Clin Psychiatry. 1999 Jul; 60(7):442-5. PMID: 10453797

Altemus M, Jacobson KR, Debellis M, Kling M, Pigott T, Murphy DL, Gold PW. Normal CSF oxytocin and NPY levels in OCD. Biol Psychiatry. 1999 Apr 1; 45(7):931-3. PMID: 10202583

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 103 publications over 18 distinct years, with a maximum of 15 publications in 2025

Bar chart showing 103 publications over 18 distinct years, with a maximum of 15 publications in 2025

Year	Publications
1999	2
2002	1
2010	1
2011	2
2012	2
2013	3
2015	2
2016	2
2017	3
2018	8
2019	5
2020	6
2021	12
2022	11
2023	13
2024	12
2025	15
2026	3

Media Mentions

Best of The Brink 2022: BU’s Most-Read Science and Research Stories

BU Today 12/13/2022

The One COVID Taboo Left

Slate 7/20/2022

Still testing positive after day 10? How to decide when to end your COVID isolation

NPR 6/30/2022

Dr. Karen Jacobson from Boston University School of Medicine discusses a new study into how long vaccinated people with COVID remain infectious

Boston 25 News 6/27/2022

A Bellwether for COVID-19

Harvard Medical School 6/8/2022

Is Five Days of COVID Isolation Enough? New BU Study Has Some Answers

BU Today 4/12/2022

BU Scientists Are Prepared to Detect Omicron—and Other Variants

BU Today 12/9/2021

Scientists race to define Omicron threat, worried about ‘surge upon a surge’

The Harvard Gazette 12/9/2021

Experts: Current tests detect Omicron variant, but transmissibility a concern

UPI 12/7/2021

Projected Long-Term Impact of the COVID-19 Pandemic on Outcomes Associated With Hepatitis C Virus

Infection Disease Advisor 10/7/2021

Councilors, medical experts push for more in-person learning at Newton schools

Wicked Local 1/11/2021

COVID-19 Biorepository Builds Opportunity for Care Equity

HealthCity 12/17/2020

CDC Director Appointee Rochelle Walensky “Won’t Be Susceptible to Political Pressure”

The Brink 12/8/2020

The Superspreading Presidency of Donald Trump

Wired 10/7/2020

New method may allow real-time surveillance of drug-resistant TB

The Daily Star 8/19/2018

In addition to these self-described keywords below, a list of MeSH based concepts is available here.

alcohol
drug resistant tuberculosis
global health
spatial mapping
tuberculosis

Available to Mentor as: (Review Mentor Role Definitions):