John H. Schwartz, MD
Emeritus Professor
Boston University School of Medicine
Dept of Medicine

MD, New York University

John H. Schwartz, M.D. is a Professor of Medicine and has been a member of the Renal Section at BUSM since 1977. In addition to teaching and conducting research, Dr. Schwartz also mentors physician scientists at GMS. Dr. Schwartz grew up in Fall River, Ma and attended BU for his undergraduate degree in Biology. As an undergraduate, Dr. Schwartz became interested in basic research and was involved in an NSF sponsorship program for undergraduates. He went on to earn his MD at the New York University School of Medicine. He then completed an internship-residency in Internal Medicine and a Post Doctoral Fellowship in Nephrology at the Beth Israel Hospital in Boston. He trained in the laboratory of Dr. Philip Steinmetz at Harvard Medical School. In 1971 he became a staff member of the renal unit at the Walter Reed Army Institute of Research, eventually acting as chief of the unit from 1973 to 1977. Dr. Schwartz has made research contributions in a number of areas including the cellular regulation of H+ transport in renal epithelia, coupling in excitable cells and pathogenesis of acute renal failure. His research is supported by grants from NIH.

Graduate Faculty (Primary Mentor of Grad Students)
Boston University School of Medicine, Division of Graduate Medical Sciences

Active Staff Privileges
Boston Medical Center

H+-ATPase and AQP2: Regulation of targeting and recycling in IMCD cells
07/01/2008 - 06/30/2014 (PI)

Snares in Trafficking of IMCD Ht
03/01/2002 - 12/31/2007 (PI)

Mechanism Of Renal Tubular Epi
07/01/1998 - 05/31/2007 (PI)

Default Pathway Of Apoptosis
01/01/1992 - 08/31/2004 (PI)
Univ of Chicago DHHS

Function of SNAP-23 inHt-AT
07/01/2003 - 06/30/2004 (PI)

Career Enhancement Grant
06/01/2001 - 06/30/2003 (PI)
Amer Soc Nephrology

Yr Title Project-Sub Proj Pubs
2011 H+-ATPase And AQP2: Regulation Of Targeting And Recycling In IMCD Cells 5R01DK059529-09 10
2010 H+-ATPase And AQP2: Regulation Of Targeting And Recycling In IMCD Cells 5R01DK059529-08 10
2009 H+-ATPase And AQP2: Regulation Of Targeting And Recycling In IMCD Cells 5R01DK059529-07 10
2008 H+-ATPase And AQP2: Regulation Of Targeting And Recycling In IMCD Cells 2R01DK059529-06A2 10
2006 SNAREs In The Trafficking Of IMCD H+-Atpase And AQP2 5R01DK059529-05 10
2005 SNAREs In The Trafficking Of IMCD H+-Atpase And AQP2 5R01DK059529-04 10
2005 Mechanism Of Renal Tubular Cell Injury 5R01DK052898-08 25
2004 SNAREs In The Trafficking Of IMCD H+-Atpase And AQP2 5R01DK059529-03 10
2004 Mechanism Of Renal Tubular Cell Injury 5R01DK052898-07 25
2003 SNAREs In The Trafficking Of IMCD H+-Atpase And AQP2 5R01DK059529-02 10
Showing 10 of 16 results. Show All Results
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Wang Z, Gall JM, Bonegio R, Havasi A, Illanes K, Schwartz JH, Borkan SC. Correction for Wang et al., "Nucleophosmin, a Critical Bax Cofactor in Ischemia-Induced Cell Death". Mol Cell Biol. 2017 Oct 01; 37(19).View Related Profiles. PMID: 28899998.
  2. Arafa E, Bondzie PA, Rezazadeh K, Meyer RD, Hartsough E, Henderson JM, Schwartz JH, Chitalia V, Rahimi N. TMIGD1 is a novel adhesion molecule that protects epithelial cells from oxidative cell injury. Am J Pathol. 2015 Oct; 185(10):2757-67.View Related Profiles. PMID: 26342724; PMCID: PMC4607757; DOI: 10.1016/j.ajpath.2015.06.006;.
  3. Coon SD, Rajendran VM, Schwartz JH, Singh SK. Glucose-dependent insulinotropic polypeptide-mediated signaling pathways enhance apical PepT1 expression in intestinal epithelial cells. Am J Physiol Gastrointest Liver Physiol. 2015 Jan 1; 308(1):G56-62.View Related Profiles. PMID: 25377315; PMCID: PMC4281688; DOI: 10.1152/ajpgi.00168.2014;.
  4. Coon SD, Schwartz JH, Rajendran VM, Jepeal L, Singh SK. Glucose-dependent insulinotropic polypeptide regulates dipeptide absorption in mouse jejunum. Am J Physiol Gastrointest Liver Physiol. 2013 Nov 15; 305(10):G678-84.View Related Profiles. PMID: 24072682; PMCID: PMC3840233; DOI: 10.1152/ajpgi.00098.2013;.
  5. Wang Z, Gall JM, Bonegio R, Havasi A, Illanes K, Schwartz JH, Borkan SC. Nucleophosmin, a critical Bax cofactor in ischemia-induced cell death. Mol Cell Biol. 2013 May; 33(10):1916-24.View Related Profiles. PMID: 23459946; PMCID: PMC3647959; DOI: 10.1128/MCB.00015-13;.
  6. Patel VA, Feng L, Lee DJ, Massenburg D, Pattabiraman G, Antoni A, Schwartz JH, Lieberthal W, Rauch J, Ucker DS, Levine JS. Recognition-dependent signaling events in response to apoptotic targets inhibit epithelial cell viability by multiple mechanisms: implications for non-immune tissue homeostasis. J Biol Chem. 2012 Apr 20; 287(17):13761-77. PMID: 22396534; PMCID: PMC3340168; DOI: 10.1074/jbc.M112.350843;.
  7. Gall JM, Wang Z, Liesa M, Molina A, Havasi A, Schwartz JH, Shirihai O, Borkan SC, Bonegio RG. Role of mitofusin 2 in the renal stress response. PLoS One. 2012; 7(1):e31074.View Related Profiles. PMID: 22292091; PMCID: PMC3266928; DOI: 10.1371/journal.pone.0031074;.
  8. Gall JM, Wong V, Pimental DR, Havasi A, Wang Z, Pastorino JG, Bonegio RG, Schwartz JH, Borkan SC. Hexokinase regulates Bax-mediated mitochondrial membrane injury following ischemic stress. Kidney Int. 2011 Jun; 79(11):1207-16.View Related Profiles. PMID: 21430642; PMCID: PMC3361076; DOI: 10.1038/ki.2010.532;.
  9. Wang Z, Gall JM, Bonegio RG, Havasi A, Hunt CR, Sherman MY, Schwartz JH, Borkan SC. Induction of heat shock protein 70 inhibits ischemic renal injury. Kidney Int. 2011 Apr; 79(8):861-70.View Related Profiles. PMID: 21270764; DOI: 10.1038/ki.2010.527;.
  10. Schwartz JH, Alexander EA. Adaptation of intercalated cells along the collecting duct to systemic acid/base changes. Kidney Int. 2010 Nov; 78(10):949-51.View Related Profiles. PMID: 21030969; DOI: 10.1038/ki.2010.343;.
Showing 10 of 124 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 105 publications over 36 distinct years, with a maximum of 8 publications in 1989 and 1990

In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Acid-Base Balance
Cell Polarity

Available to Mentor as: (Review Mentor Role Definitions):
  • Advisor
  • Career Mentor
  • Co-Mentor or Peer Mentor
Contact for Mentoring:

650 Albany St Evans Biomed Research Ctr
Boston MA 02118
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