Jessica L. Fetterman, PhD
Assistant Professor
Boston University School of Medicine
Dept of Medicine
Vascular Biology

PhD, University of Alabama at Birmingham




Dr. Fetterman is a basic and translational scientist studying the intersections of mitochondrial physiology, mitochondrial genetic epidemiology, and cardiovascular disease. Her work focuses on the contribution of mitochondrial genetic variation and abnormalities to cardiovascular disease in the presence of risk factors, including tobacco product use and diabetes.

Using bioinformatics methods, Dr. Fetterman discovered that several select mitochondrial genetic variants are associated with non-invasive measures of vascular function within the Framingham Heart Study (FHS). Additionally, she has applied similar methodology to select mitochondrial single variant data within Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) to determine the associations of select mitochondrial genetic variants with cardiometabolic measures in collaboration with members of the mitochondrial genetics working group. Recently, Dr. Fetterman was awarded the competitive Trans-Omics Precision Medicine (TOPMed) Analytical Support Award for early career investigators to perform comprehensive bioinformatic annotation of the mitochondrial genetic variants within the TOPMed cohorts.

Dr. Fetterman also conducts research on the impact of new and emerging tobacco products on the vasculature, particularly studies designed to inform tobacco product regulation. Some of her recent work demonstrated that tobacco product flavoring additives induce vascular endothelial dysfunction, an early indicator of cardiovascular injury. She serves as an Associate Director of Education and Training within American Heart Association Tobacco Regulation and Addiction Center. Additionally, she is the Director for the Boston University Tobacco Regulatory Science Affinity Research Collaborative, which is designed to bring together multi-disciplinary teams of scientists within Boston University to increase our understanding of tobacco product use patterns and the impact of new and emerging tobacco products on human health and disease.

Investigator
Framingham Heart Study


Member
Boston University
Whitaker Cardiovascular Institute


Member
Boston University
Evans Center for Interdisciplinary Biomedical Research



2019 Boston University : Junior Faculty Mentoring Award
2010 University of Alabama at Birmingham: Center for Free Radical Biology Travel Award
2010 University of Alabama at Birmingham: Ireland Research Travel Award
2009 University of Alabama at Birmingham: Center for Free Radical Biology Travel Award
2009 University of Alabama in Birmingham: 2nd Place at the Vascular Biology and Hypertension Symposium


Relations of Mitochondrial Genetic Variation and Function with Atrial Fibrillation
04/01/2019 - 03/31/2024 (PI)
NIH/National Heart, Lung, and Blood Institute
5K01HL143142-02

E-cigarette-Induced Endothelial Dysfunction in Human Participants
01/01/2017 - 12/31/2018 (PI)
American Heart Association


AHA Tobacco Regulation and Addiction Center: Vascular Core Laboratory
07/01/2016 - 08/31/2018 (PI of Sub-Project / SP)
American Heart Association NIH NHLBI
5P50HL120163-05

TOPMed Informatics Resource Center - Data and Working Group Support
04/01/2017 - 04/30/2018 (Subcontract PI)
University of Michigan NIH NHLBI
5R01HL117626-05

American Heart Association Tobacco Regulation and Addiction Center (A-TRACT) - Project 2: Cardiovascular Injury due to Tobacco Use
09/19/2013 - 06/30/2017 (PI of Sub-Project / SP)
American Heart Association NIH NHLBI
5P50HL120163-03



Title


Yr Title Project-Sub Proj Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Harlow AF, Fetterman JL, Ross CS, Robertson RM, Bhatnagar A, Benjamin EJ, Stokes AC. Association of device type, flavours and vaping behaviour with tobacco product transitions among adult electronic cigarette users in the USA. Tob Control. 2021 Jan 21.View Related Profiles. PMID: 33479031
     
  2. Hong T, Wu J, Wijaya D, Xuan Z, Fetterman JL. JUUL the heartbreaker: Twitter analysis of cardiovascular health perceptions of vaping. Tob Induc Dis. 2021; 19:01.View Related Profiles. PMID: 33437228; DOI: 10.18332/tid/130961;
     
  3. Stokes AC, Xie W, Wilson AE, Yang H, Orimoloye OA, Harlow AF, Fetterman JL, DeFilippis AP, Benjamin EJ, Robertson RM, Bhatnagar A, Hamburg NM, Blaha MJ. Association of Cigarette and Electronic Cigarette Use Patterns With Levels of Inflammatory and Oxidative Stress Biomarkers Among US Adults: Population Assessment of Tobacco and Health Study. Circulation. 2021 Feb 23; 143(8):869-871.View Related Profiles. PMID: 33390037
     
  4. Hughes WE, Chabowski DS, Ait-Aissa K, Fetterman JL, Hockenberry J, Beyer AM, Gutterman DD. Critical Interaction Between Telomerase and Autophagy in Mediating Flow-Induced Human Arteriolar Vasodilation. Arterioscler Thromb Vasc Biol. 2021 01; 41(1):446-457. PMID: 33232201
     
  5. Stokes A, Wilson AE, Lundberg DJ, Xie W, Berry KM, Fetterman JL, Harlow AF, Cozier YC, Barrington-Trimis JL, Sterling KL, Benjamin EJ, Blaha MJ, Hamburg NM, Bhatnagar A, Robertson RM. Racial/Ethnic Differences in Associations of Noncigarette Tobacco Product Use with Subsequent Initiation of Cigarettes in US Youths. Nicotine Tob Res. 2020 Sep 19.View Related Profiles. PMID: 32948872
     
  6. Masaki N, Feng B, Bretón-Romero R, Inagaki E, Weisbrod RM, Fetterman JL, Hamburg NM. O-GlcNAcylation Mediates Glucose-Induced Alterations in Endothelial Cell Phenotype in Human Diabetes Mellitus. J Am Heart Assoc. 2020 06 16; 9(12):e014046.View Related Profiles. PMID: 32508185
     
  7. Di Frances CD, Childs E, Fetterman JL, Villanti AC, Stanton CA, Russo AR, Hirsch GA, Solis AC, Benjamin EJ. Implementing and Evaluating a Mentor Training to Improve Support for Early-Career Scholars in Tobacco Regulatory Science. Nicotine Tob Res. 2020 05 26; 22(6):1041-1045.View Related Profiles. PMID: 31095330
     
  8. Fetterman JL, Keith RJ, Palmisano JN, McGlasson KL, Weisbrod RM, Majid S, Bastin R, Stathos MM, Stokes AC, Robertson RM, Bhatnagar A, Hamburg NM. Alterations in Vascular Function Associated With the Use of Combustible and Electronic Cigarettes. J Am Heart Assoc. 2020 05 05; 9(9):e014570.View Related Profiles. PMID: 32345096
     
  9. Keith RJ, Fetterman JL, Orimoloye OA, Dardari Z, Lorkiewicz PK, Hamburg NM, DeFilippis AP, Blaha MJ, Bhatnagar A. Characterization of Volatile Organic Compound Metabolites in Cigarette Smokers, Electronic Nicotine Device Users, Dual Users, and Nonusers of Tobacco. Nicotine Tob Res. 2020 02 06; 22(2):264-272.View Related Profiles. PMID: 30759242
     
  10. Fetterman JL, Ballinger SW. Mitochondrial genetics regulate nuclear gene expression through metabolites. Proc Natl Acad Sci U S A. 2019 08 06; 116(32):15763-15765. PMID: 31308238
     
Showing 10 of 35 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 35 publications over 10 distinct years, with a maximum of 8 publications in 2018

YearPublications
20111
20121
20134
20142
20165
20172
20188
20193
20206
20213


Survey data indicating teen e-cig use is down may be flawed due to a loophole in flavor ban

Legal Reader 9/23/2020

Vaping Has Same Heart Disease Risk as Smoking

The Star Online 5/9/2020

E-cigarette Use Causes as Much Vascular Damage as Smoking cigarettes

Cardiovascular Business 4/30/2020

New Study Suggests Vaping Can Damage Our Heart The Same Way Smoking Does

Medical Daily 4/30/2020

Study: E-Cigarettes as Bad for Arteries as Regular Cigarettes

Newsmax 4/30/2020

Like Tobacco, Long-term E-Cigarettes Harm Vascular Function

TctMD 4/30/2020

E-Cigarette, Traditional Cigarette Use Result in Similar Vascular Damage

MD Magazine 4/30/2020

Vaping may damage the heart just as smoking does

Science News 4/29/2020

Vaping is just as bad as smoking cigarettes for increasing the risk of heart disease ‘because it stiffens blood vessels in the same way’

Daily Mail 4/29/2020

New Study Finds E-cigarette May Cause Similar Damage to the Arteries as Tobacco Cigarettes

Yahoo News 4/29/2020

Vaping is just as bad as smoking cigarettes for increasing the risk of heart disease 'because it stiffens blood vessels in the same way’

The Daily Mail 4/29/2020

E-cigarettes fail to improve vascular profile vs. combustible cigarettes

Healio 4/29/2020

E-Cigarettes as Bad for Arteries as Regular Smokes, Study Finds

Health Day 4/29/2020

Study: E-cigarettes damage vascular function much like traditional cigarettes

News Medical: 4/29/2020

E-cig flavorings may damage lining of blood vessels

Community Health 2/15/2019

‘Fine, I’ll just vape without the nicotine.’ Not so fast! E-cig flavorings may cause damage all by themselves

Dentistry IQ 1/24/2019

E-Cigarettes Aren't Any Safer Than Regular Cigarettes, Especially With Kids Around

Moms 11/29/2018

E-cigarette flavorings may damage blood vessels and heart

WHBL 7/11/2018

E-Cigarette Flavorings May Harm Blood Vessels

MedPage Today 6/14/2018
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Mitochondria
Mitochondrial DNA
Tobacco Smoking
E-cigarettes
Tobacco Regulatory Science
Vascular Endothelium

Dr. Fetterman is willing to mentor fellows, graduate students, and undergraduates interested in either mitochondrial physiology or tobacco regulatory science.

Available to Mentor as: (Review Mentor Role Definitions):
  • Advisor
  • Career Mentor
  • Co-Mentor or Peer Mentor
  • Diversity Mentor
  • Project Mentor
  • Research / Scholarly Mentor
  • Work / Life Integration Mentor
Contact for Mentoring:
  • Email (see 'Contact Info')

75 E. Newton St Evans Building
Boston MA 02118
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