Seung Hoan Choi, PhD
Research Assistant Professor
Boston University School of Public Health

PhD, Boston University
MA, Boston University
BS, Stony Brook University

Pronouns: he/him/his

Dr. Choi's work is at the interface of statistics and genetics, developing and applying statistical methods to further our understanding of the genetics of complex diseases. He has developed his analytic capabilities in genetics, statistics, and large-scale data processing. Dr. Choi’s recent work has used this foundation to elucidate the genetic basis of a common and complex disease, atrial fibrillation. He has led or contributed to many important findings in cardiometabolic genetics and is considered a key investigator in the field.

Dr. Choi received his PhD in Biostatistics from Boston University School of Public Health in 2016 with his focused research in statistical genetics. He then completed a postdoctoral fellowship at the Broad Institute of MIT and Harvard. He also previously held the position of Computational Scientist II at the Broad Institute of MIT and Harvard.

Understanding airway mucus dysfunction in population-based studies
08/15/2022 - 07/31/2026 (Subcontract PI)
The Brigham and Women's Hospital, Inc. NIH NHLBI

Nutritional Omics of Pulmonary Function Decline
11/15/2019 - 07/31/2024 (Subcontract PI)
RTI International NIH NHLBI


Yr Title Project-Sub Proj Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. Wang B, Dron JS, Wang Y, Choi SH, Huffman JE, Cho K, Wilson PWF, Natarajan P, Peloso GM. Lipid levels and risk of acute pancreatitis using bidirectional Mendelian randomization. Sci Rep. 2024 Mar 15; 14(1):6267.View Related Profiles. PMID: 38491158; PMCID: PMC10942988; DOI: 10.1038/s41598-024-56946-x;
  2. Lee WP, Choi SH, Shea MG, Cheng PL, Dombroski BA, Pitsillides AN, Heard-Costa NL, Wang H, Bulekova K, Kuzma AB, Leung YY, Farrell JJ, Lin H, Naj A, Blue EE, Nusetor F, Wang D, Boerwinkle E, Bush WS, Zhang X, De Jager PL, Dupuis J, Farrer LA, Fornage M, Martin E, Pericak-Vance M, Seshadri S, Wijsman EM, Wang LS, Schellenberg GD, Destefano AL, Haines JL, Peloso GM. Association of Common and Rare Variants with Alzheimer's Disease in over 13,000 Diverse Individuals with Whole-Genome Sequencing from the Alzheimer's Disease Sequencing Project. medRxiv. 2023 Sep 02.View Related Profiles. PMID: 37693521; PMCID: PMC10491367; DOI: 10.1101/2023.09.01.23294953;
  3. Wang Y, Sarnowski C, Lin H, Pitsillides AN, Heard-Costa NL, Choi SH, Wang D, Bis JC, Blue EE, Boerwinkle E, De Jager PL, Fornage M, Wijsman EM, Seshadri S, Dupuis J, Peloso GM, DeStefano AL. Key variants via Alzheimer's Disease Sequencing Project whole genome sequence data. medRxiv. 2023 Aug 29.View Related Profiles. PMID: 37693453; PMCID: PMC10491364; DOI: 10.1101/2023.08.28.23294631;
  4. Wang X, Khurshid S, Choi SH, Friedman S, Weng LC, Reeder C, Pirruccello JP, Singh P, Lau ES, Venn R, Diamant N, Di Achille P, Philippakis A, Anderson CD, Ho JE, Ellinor PT, Batra P, Lubitz SA. Genetic Susceptibility to Atrial Fibrillation Identified via Deep Learning of 12-Lead Electrocardiograms. Circ Genom Precis Med. 2023 Aug; 16(4):340-349. PMID: 37278238; PMCID: PMC10524395; DOI: 10.1161/CIRCGEN.122.003808;
  5. Pham C, Andrzejczyk K, Jurgens SJ, Lekanne Deprez R, Palm KCA, Vermeer AMC, Nijman J, Christiaans I, Barge-Schaapveld DQCM, van Dessel PFHM, Beekman L, Choi SH, Lubitz SA, Skoric-Milosavljevic D, van den Bersselaar L, Jansen PR, Copier JS, Ellinor PT, Wilde AAM, Bezzina CR, Lodder EM. Genetic Burden of TNNI3K in Diagnostic Testing of Patients With Dilated Cardiomyopathy and Supraventricular Arrhythmias. Circ Genom Precis Med. 2023 Aug; 16(4):328-336. PMID: 37199186; PMCID: PMC10426786; DOI: 10.1161/CIRCGEN.122.003975;
  6. Rämö JT, Abner E, van Dijk EHC, Wang X, Brinks J, Nikopensius T, Nõukas M, Marjonen H, Silander K, Jukarainen S, Kiiskinen T, Choi SH, Kajanne R, Mehtonen J, Palta P, Lubitz SA, Kaarniranta K, Sobrin L, Kurki M, Yzer S, Ellinor PT, Esko T, Daly MJ, den Hollander AI, Palotie A, Turunen JA, Boon CJF, Rossin EJ. Overlap of Genetic Loci for Central Serous Chorioretinopathy With Age-Related Macular Degeneration. JAMA Ophthalmol. 2023 May 01; 141(5):449-457. PMID: 37079300; PMCID: PMC10119776; DOI: 10.1001/jamaophthalmol.2023.0706;
  7. Nauffal V, Di Achille P, Klarqvist MDR, Cunningham JW, Hill MC, Pirruccello JP, Weng LC, Morrill VN, Choi SH, Khurshid S, Friedman SF, Nekoui M, Roselli C, Ng K, Philippakis AA, Batra P, Ellinor PT, Lubitz SA. Genetics of myocardial interstitial fibrosis in the human heart and association with disease. Nat Genet. 2023 May; 55(5):777-786. PMID: 37081215; DOI: 10.1038/s41588-023-01371-5;
  8. Wang X, Ryu J, Kim J, Ramirez A, Mayo KR, Condon H, Vaitinadin NS, Ohno-Machado L, Talavera GA, Ellinor PT, Lubitz SA, Choi SH. Common and rare variants associated with cardiometabolic traits across 98,622 whole-genome sequences in the All of Us research program. J Hum Genet. 2023 Aug; 68(8):565-570. PMID: 37072623; PMCID: PMC10524735; DOI: 10.1038/s10038-023-01147-z;
  9. Pirruccello JP, Rämö JT, Choi SH, Chaffin MD, Kany S, Nekoui M, Chou EL, Jurgens SJ, Friedman SF, Juric D, Stone JR, Batra P, Ng K, Philippakis AA, Lindsay ME, Ellinor PT. The Genetic Determinants of Aortic Distention. J Am Coll Cardiol. 2023 Apr 11; 81(14):1320-1335. PMID: 37019578; DOI: 10.1016/j.jacc.2023.01.044;
  10. Jurgens SJ, Pirruccello JP, Choi SH, Morrill VN, Chaffin M, Lubitz SA, Lunetta KL, Ellinor PT. Adjusting for common variant polygenic scores improves yield in rare variant association analyses. Nat Genet. 2023 Mar 23. PMID: 36959364
Showing 10 of 69 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 68 publications over 15 distinct years, with a maximum of 10 publications in 2022 and 2023


2021 Broad Institute of MIT and Harvard: CHARGE Seattle Meeting Travel Award
2013 Framingham Heart Study: CHARGE Rotterdam Meeting Travel Award
2012 Framingham Heart Study: CHARGE Reykjavik Meeting Travel Award
2009-2016 Boston University: Graduate Research Assistant Scholarship Program
2008 The State University of New York at Stony Brook: Cum Laude
Contact for Mentoring:

801 Massachusetts Ave
Boston MA 02118
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