Seiko   Ikezu, MD
Research Assistant Professor
Boston University School of Medicine
Dept of Pharmacology & Experimental Therapeutics

MD, Gunma University





Characterization of Microglial Signaling in Maternal Immune Activation-related Autism
08/01/2018 - 07/31/2020 (Co-PI)
PI: Tsuneya Ikezu, MD, PhD
Landreth Family Foundation




Title


Yr Title Project-Sub Proj Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. Muraoka S, DeLeo AM, Sethi MK, Yukawa-Takamatsu K, Yang Z, Ko J, Hogan JD, Ruan Z, You Y, Wang Y, Medalla M, Ikezu S, Chen M, Xia W, Gorantla S, Gendelman HE, Issadore D, Zaia J, Ikezu T. Proteomic and biological profiling of extracellular vesicles from Alzheimer's disease human brain tissues. Alzheimers Dement. 2020 06; 16(6):896-907.View Related Profiles. PMID: 32301581
     
  2. Ikezu S, Yeh H, Delpech JC, Woodbury ME, Van Enoo AA, Ruan Z, Sivakumaran S, You Y, Holland C, Guillamon-Vivancos T, Yoshii-Kitahara A, Botros MB, Madore C, Chao PH, Desani A, Manimaran S, Kalavai SV, Johnson WE, Butovsky O, Medalla M, Luebke JI, Ikezu T. Inhibition of colony stimulating factor 1 receptor corrects maternal inflammation-induced microglial and synaptic dysfunction and behavioral abnormalities. Mol Psychiatry. 2020 Feb 18.View Related Profiles. PMID: 32071385
     
  3. Ikezu S, Ingraham Dixie KL, Koro L, Watanabe T, Kaibuchi K, Ikezu T. Tau-tubulin kinase 1 and amyloid-ß peptide induce phosphorylation of collapsin response mediator protein-2 and enhance neurite degeneration in Alzheimer disease mouse models. Acta Neuropathol Commun. 2020 02 04; 8(1):12.View Related Profiles. PMID: 32019603
     
  4. Muraoka S, Jedrychowski MP, Tatebe H, DeLeo AM, Ikezu S, Tokuda T, Gygi SP, Stern RA, Ikezu T. Proteomic Profiling of Extracellular Vesicles Isolated From Cerebrospinal Fluid of Former National Football League Players at Risk for Chronic Traumatic Encephalopathy. Front Neurosci. 2019; 13:1059.View Related Profiles. PMID: 31649498
     
  5. Varnum MM, Clayton KA, Yoshii-Kitahara A, Yonemoto G, Koro L, Ikezu S, Ikezu T. A split-luciferase complementation, real-time reporting assay enables monitoring of the disease-associated transmembrane protein TREM2 in live cells. J Biol Chem. 2017 Jun 23; 292(25):10651-10663.View Related Profiles. PMID: 28490631
     
  6. Asai H, Ikezu S, Tsunoda S, Medalla M, Luebke J, Haydar T, Wolozin B, Butovsky O, Kügler S, Ikezu T. Depletion of microglia and inhibition of exosome synthesis halt tau propagation. Nat Neurosci. 2015 Nov; 18(11):1584-93.View Related Profiles. PMID: 26436904; PMCID: PMC4694577; DOI: 10.1038/nn.4132;
     
  7. Varnum MM, Kiyota T, Ingraham KL, Ikezu S, Ikezu T. The anti-inflammatory glycoprotein, CD200, restores neurogenesis and enhances amyloid phagocytosis in a mouse model of Alzheimer's disease. Neurobiol Aging. 2015 Nov; 36(11):2995-3007.View Related Profiles. PMID: 26315370; PMCID: PMC4772879; DOI: 10.1016/j.neurobiolaging.2015.07.027;
     
  8. Woodbury ME, Freilich RW, Cheng CJ, Asai H, Ikezu S, Boucher JD, Slack F, Ikezu T. miR-155 Is Essential for Inflammation-Induced Hippocampal Neurogenic Dysfunction. J Neurosci. 2015 Jul 1; 35(26):9764-81.View Related Profiles. PMID: 26134658; PMCID: PMC4571507; DOI: 10.1523/JNEUROSCI.4790-14.2015;
     
  9. Ikezu S, Ikezu T. Tau-tubulin kinase. Front Mol Neurosci. 2014; 7:33.View Related Profiles. PMID: 24808823; DOI: 10.3389/fnmol.2014.00033;
     
  10. Asai H, Ikezu S, Woodbury ME, Yonemoto GM, Cui L, Ikezu T. Accelerated neurodegeneration and neuroinflammation in transgenic mice expressing P301L tau mutant and tau-tubulin kinase 1. Am J Pathol. 2014 Mar; 184(3):808-18.View Related Profiles. PMID: 24418258; PMCID: PMC3936332; DOI: 10.1016/j.ajpath.2013.11.026;
     

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 10 publications over 5 distinct years, with a maximum of 3 publications in 2015 and 2020

YearPublications
20142
20153
20171
20191
20203

Contact for Mentoring:

72 E. Concord St Instructional (L)
Boston MA 02118
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