Hirohide Asai

Postdoctoral Fellow (previously held)

Boston University Chobanian & Avedisian School of Medicine

BU Research

The cellular mechanism of tau dissemination
07/01/2013 - 06/30/2015 (PI)
Bright Focus Foundation

Title

Yr	Title	Project-Sub Proj	Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis Copy PMIDs To Clipboard

Imamura T, Yanagihara YT, Ohyagi Y, Nakamura N, Iinuma KM, Yamasaki R, Asai H, Maeda M, Murakami K, Irie K, Kira JI. Insulin deficiency promotes formation of toxic amyloid-ß42 conformer co-aggregating with hyper-phosphorylated tau oligomer in an Alzheimer's disease model. Neurobiol Dis. 2020 04; 137:104739. PMID: 31927145

Zhou Q, Yen A, Rymarczyk G, Asai H, Trengrove C, Aziz N, Kirber MT, Mostoslavsky G, Ikezu T, Wolozin B, Bolotina VM. Impairment of PARK14-dependent Ca(2+) signalling is a novel determinant of Parkinson's disease. Nat Commun. 2016; 7:10332.View Related Profiles.

Yen, Allen
Wolozin, Benjamin
Trengrove, Chelsea
Mostoslavsky, Gustavo
Asai, Hirohide
Kirber, Michael
Aziz, Nadine
Zhou, Qingde
Ikezu, Tsuneya
Bolotina, Victoria

PMID: 26755131; PMCID: PMC4729940; DOI: 10.1038/ncomms10332;

Asai H, Ikezu S, Tsunoda S, Medalla M, Luebke J, Haydar T, Wolozin B, Butovsky O, Kügler S, Ikezu T. Depletion of microglia and inhibition of exosome synthesis halt tau propagation. Nat Neurosci. 2015 Nov; 18(11):1584-93.View Related Profiles.

Wolozin, Benjamin
Asai, Hirohide
Luebke, Jennifer
Medalla, Maria
Ikezu, Seiko
Haydar, Tarik
Ikezu, Tsuneya

PMID: 26436904; PMCID: PMC4694577; DOI: 10.1038/nn.4132;

Woodbury ME, Freilich RW, Cheng CJ, Asai H, Ikezu S, Boucher JD, Slack F, Ikezu T. miR-155 Is Essential for Inflammation-Induced Hippocampal Neurogenic Dysfunction. J Neurosci. 2015 Jul 1; 35(26):9764-81.View Related Profiles.

Asai, Hirohide
Woodbury, Maya
Freilich, Robert
Ikezu, Seiko
Ikezu, Tsuneya

PMID: 26134658; PMCID: PMC4571507; DOI: 10.1523/JNEUROSCI.4790-14.2015;

Jun G, Asai H, Zeldich E, Drapeau E, Chen C, Chung J, Park JH, Kim S, Haroutunian V, Foroud T, Kuwano R, Haines JL, Pericak-Vance MA, Schellenberg GD, Lunetta KL, Kim JW, Buxbaum JD, Mayeux R, Ikezu T, Abraham CR, Farrer LA. PLXNA4 is associated with Alzheimer disease and modulates tau phosphorylation. Ann Neurol. 2014 Sep; 76(3):379-92.View Related Profiles.

Abraham, Carmela
Chen, Ci-Di
Zeldich, Ella
Jun, Gyungah
Asai, Hirohide
Chung, Jaeyoon
Lunetta, Kathryn
Farrer, Lindsay
Ikezu, Tsuneya

PMID: 25043464; PMCID: PMC4830273; DOI: 10.1002/ana.24219;

Asai H, Ikezu S, Woodbury ME, Yonemoto GM, Cui L, Ikezu T. Accelerated neurodegeneration and neuroinflammation in transgenic mice expressing P301L tau mutant and tau-tubulin kinase 1. Am J Pathol. 2014 Mar; 184(3):808-18.View Related Profiles.

Asai, Hirohide
Woodbury, Maya
Ikezu, Seiko
Ikezu, Tsuneya

PMID: 24418258; PMCID: PMC3936332; DOI: 10.1016/j.ajpath.2013.11.026;

Asai H, Hirano M, Kiriyama T, Ikeda M, Ueno S. Naturally- and experimentally-designed restorations of the Parkin gene deficit in autosomal recessive juvenile parkinsonism. Biochem Biophys Res Commun. 2010 Jan 1; 391(1):800-5. PMID: 19945426

Asai H, Hirano M, Shimada K, Kiriyama T, Furiya Y, Ikeda M, Iwamoto T, Mori T, Nishinaka K, Konishi N, Udaka F, Ueno S. Protein kinase C gamma, a protein causative for dominant ataxia, negatively regulates nuclear import of recessive-ataxia-related aprataxin. Hum Mol Genet. 2009 Oct 1; 18(19):3533-43. PMID: 19561170

Asai H, Hirano M, Furiya Y, Udaka F, Morikawa M, Kanbayashi T, Shimizu T, Ueno S. Cerebrospinal fluid-orexin levels and sleep attacks in four patients with Parkinson's disease. Clin Neurol Neurosurg. 2009 May; 111(4):341-4. PMID: 19097685

Tonomura Y, Hirano M, Shimada K, Asai H, Ikeda M, Kataoka H, Tanaka I, Konishi N, Ueno S. Treatable fluctuating mental impairment in a patient with Bardet-Biedl syndrome. Clin Neurol Neurosurg. 2009 Jan; 111(1):102-4. PMID: 18938027

Showing 10 of 34 results. Show More

Kiriyama T, Hirano M, Asai H, Ikeda M, Furiya Y, Ueno S. Restoration of nuclear-import failure caused by triple A syndrome and oxidative stress. Biochem Biophys Res Commun. 2008 Oct 3; 374(4):631-4. PMID: 18662670

Asai H, Udaka F, Hirano M, Ueno S. Odor abnormalities caused by bilateral thalamic infarction. Clin Neurol Neurosurg. 2008 May; 110(5):500-1. PMID: 18329165

Furiya Y, Hirano M, Nomura M, Asai H, Kiriyama T, Ueno S. Peripheral neuropathy in chromosome16q22.1 linked autosomal dominant cerebellar ataxia. J Neurol Neurosurg Psychiatry. 2007 Sep; 78(9):1009-11. PMID: 17702787; PMCID: PMC2117868; DOI: 10.1136/jnnp.2006.103895;

Kiriyama T, Tanizawa E, Hirano M, Shinkai T, Asai H, Furiya Y, Ueno S. SPECT revealed cortical dysfunction in a patient who had genetically definite megalencephalic leukoencephalopathy with subcortical cysts. Clin Neurol Neurosurg. 2007 Jul; 109(6):526-30. PMID: 17507156

Hirano M, Asai H, Kiriyama T, Furiya Y, Iwamoto T, Nishiwaki T, Yamamoto A, Mori T, Ueno S. Short half-lives of ataxia-associated aprataxin proteins in neuronal cells. Neurosci Lett. 2007 May 29; 419(2):184-7. PMID: 17485165

Asai H, Hirano M, Udaka F, Shimada K, Oda M, Kubori T, Nishinaka K, Tsujimura T, Izumi Y, Konishi N, Matsumoto S, Kameyama M, Ueno S. Sympathetic disturbances increase risk of sudden cardiac arrest in sporadic ALS. J Neurol Sci. 2007 Mar 15; 254(1-2):78-83. PMID: 17303172

Hirano M, Yamamoto A, Mori T, Lan L, Iwamoto TA, Aoki M, Shimada K, Furiya Y, Kariya S, Asai H, Yasui A, Nishiwaki T, Imoto K, Kobayashi N, Kiriyama T, Nagata T, Konishi N, Itoyama Y, Ueno S. DNA single-strand break repair is impaired in aprataxin-related ataxia. Ann Neurol. 2007 Feb; 61(2):162-74. PMID: 17315206

Hirano M, Furiya Y, Asai H, Yasui A, Ueno S. ALADINI482S causes selective failure of nuclear protein import and hypersensitivity to oxidative stress in triple A syndrome. Proc Natl Acad Sci U S A. 2006 Feb 14; 103(7):2298-303. PMID: 16467144; PMCID: PMC1413683; DOI: 10.1073/pnas.0505598103;

Asai H, Udaka F, Hirano M, Minami T, Oda M, Kubori T, Nishinaka K, Kameyama M, Ueno S. Increased gastric motility during 5-HT4 agonist therapy reduces response fluctuations in Parkinson's disease. Parkinsonism Relat Disord. 2005 Dec; 11(8):499-502. PMID: 16263322

Kariya S, Hirano M, Uesato S, Nagai Y, Nagaoka Y, Furiya Y, Asai H, Fujikake N, Toda T, Ueno S. Cytoprotective effect of novel histone deacetylase inhibitors against polyglutamine toxicity. Neurosci Lett. 2006 Jan 16; 392(3):213-5. PMID: 16199124

Asai H, Udaka F, Oishi N, Kubori T, Kameyama M. [A case of familial essential myoclonus and epilepsy with suspected focus in the hemisphere ipsilateral to myoclonus limbs]. No To Shinkei. 2004 Jun; 56(6):509-13. PMID: 15328840

Hirano M, Kusunoki S, Asai H, Tonomura Y, Morita D, Ueno S. A family with Campylobacter enteritis: anti-GD1a antibody with/without Guillain-Barré syndrome. Neurology. 2003 May 27; 60(10):1719-20. PMID: 12771281

Morimoto M, Kanno H, Asai H, Tsujimura T, Fujii H, Moriyama Y, Kasugai T, Hirono A, Ohba Y, Miwa S, Kitamura Y. Pyruvate kinase deficiency of mice associated with nonspherocytic hemolytic anemia and cure of the anemia by marrow transplantation without host irradiation. Blood. 1995 Dec 1; 86(11):4323-30. PMID: 7492793

Kanno H, Morimoto M, Fujii H, Tsujimura T, Asai H, Noguchi T, Kitamura Y, Miwa S. Primary structure of murine red blood cell-type pyruvate kinase (PK) and molecular characterization of PK deficiency identified in the CBA strain. Blood. 1995 Oct 15; 86(8):3205-10. PMID: 7579416

Kubo T, Matsunaga T, Asai H, Kawamoto K, Kusakari J, Nomura Y, Oda M, Yanagita N, Niwa H, Uemura T, et al. Efficacy of defibrinogenation and steroid therapies on sudden deafness. Arch Otolaryngol Head Neck Surg. 1988 Jun; 114(6):649-52. PMID: 3284549

Kagawa H, Nagai Y, Asai H. An analysis of the hyper-sharp phenomenon of myosin diffusion in an F-actin/ATP solution by computer simulation. Biophys Chem. 1988 Apr; 29(3):327-39. PMID: 3390528

Kanakura Y, Sonoda S, Nakano T, Fujita J, Kuriu A, Asai H, Kitamura Y. Formation of mast-cell colonies in methylcellulose by mouse skin cells and development of mucosal-like mast cells from the cloned cells in the gastric mucosa of W/Wv mice. Am J Pathol. 1987 Oct; 129(1):168-76. PMID: 3661676; PMCID: PMC1899697

Inao S, Furuse M, Hotta T, Asai H, Yoshida K, Saso K, Kaneoke Y, Motegi Y. [Hemodilutional therapy in raised intracranial pressure; observations in a case of cerebral infarction associated with polycythemia vera]. No To Shinkei. 1986 Mar; 38(3):219-24. PMID: 3707772

Hagiwara S, Konno T, Sugiyama S, Asai H, Sugiyama E, Nakamoto H, Izumi Y, Watanabe H, Noguchi T, Ishikawa I. [Epidemiological survey on dental prophylaxis and treatment by questionnaire. Primary report]. Kokubyo Gakkai Zasshi. 1985 Dec; 52(4):643-57. PMID: 3868671

Yokoyama M, Tomoi M, Taguchi T, Nakano T, Asai H, Ono T, Kitamura Y. Fatal antral ulcer in conventionally fed W/Wv mutant mice given indomethacin by injection. Am J Pathol. 1985 Jun; 119(3):367-75. PMID: 3860014; PMCID: PMC1888014

Ishikawa I, Honma S, Hagiwara S, Asai H, Osada Y, Izumi Y, Watanabe H, Izumizawa K, Noguchi T. [Epidemiological survey on periodontal disease in the employees of two banks with CPITN (Community Periodontal Index of Treatment Needs)--the primary report]. Nihon Shishubyo Gakkai Kaishi. 1984 Dec; 26(4):767-78. PMID: 6600130

Nagai Y, Asai H, Tsuchiya T. Polydispersity effects on head-to-tail polymerization of F-actin. A theoretical treatment. Biophys Chem. 1984 Nov; 20(4):319-31. PMID: 6509152

Nagai Y, Asai H, Tsuchiya T. The average number of distinct sites visited by a one-dimensional random walker and its application to isotope exchange in polypeptides. Biophys Chem. 1981 Jun; 13(3):213-22. PMID: 17000168

Asai H, Takagi H, Tsunoda S. Some characteristics of erythrocyte membrane and its ATPase from lamprey, Entosphenus japonicus. Comp Biochem Physiol B. 1976; 55(1):69-75. PMID: 7430

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 33 publications over 18 distinct years, with a maximum of 5 publications in 2007

Bar chart showing 33 publications over 18 distinct years, with a maximum of 5 publications in 2007

Year	Publications
1981	1
1984	2
1985	2
1986	1
1987	1
1988	2
1995	2
2003	1
2004	1
2005	2
2006	1
2007	5
2008	4
2009	2
2014	2
2015	2
2016	1
2020	1

Contact for Mentoring:

85 E. Concord St
Boston MA 02118
Google Map

617.638.4300

Download vCard

Asai's Networks

Click the "See All" links for more information and interactive visualizations

Concepts

See all (300) concept(s)

Co-Authors

See all (18) people

Similar People

See all (60) people